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Sequences

Sequence NM_173844

CGAGGCTCCGTGCCCCGCCCCCCGGGTGCCCCGCCCCTTTGCGCGGCTGGCGCGGCCAGCAGGCCAGGCTCCCCTCGGCAAACCTGTCTAATTGGGGCGG GGAGCGGAGCTTCCTCCTCTGAGGGCCGTGCCGCGCTGCCAGATTTGTTCTTCCGCCCCTGCCTCCGCGGCTCGGAGGCGAGCGGAAGGTGCCCCGGGGC CGAGGCCCGTGACGGGGCGGGCGGGAGCCCCGGCAGTCCGGGGTCGCCGGCGAGGGCCATGTCGCTGTTGGGGGACCCGCTACAGGCCCTGCCGCCCTCG GCCGCCCCCACGGGGCCGCTGCTCGCCCCTCCGGCCGGCGCGACCCTCAACCGCCTGCGGGAGCCGCTGCTGCGGAGGCTCAGCGAGCTCCTGGATCAGG CGCCCGAGGGCCGGGGCTGGAGGAGACTGGCGGAGCTGGCGGGGAGTCGCGGGCGCCTCCGCCTCAGTTGCCTAGACCTGGAGCAGTGTTCTCTTAAGGT ACTGGAGCCTGAAGGAAGCCCCAGCCTGTGTCTGCTGAAGTTAATGGGTGAAAAAGGTTGCACAGTCACAGAATTGAGTGATTTCCTGCAGGCTATGGAA CACACTGAAGTTCTTCAGCTTCTCAGCCCCCCAGGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTT GCCGGGCAACTGGACATCCTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTAATGCAGTGCA TGTAAAAGATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATGTTTGCGACATCCCAGAGAGC TTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGCTGATGCCAGGCAGCACATTGGTTTTACAGT GTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAACACATGAGACCAAAAAGCTATACATGGTGCCTTATGTGGA TTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACAGTCAAGATAGCAAGAAGGTAGAAATCATCATAGATGAATTAAATAATCTT GGTCATCCTGATAATAAAGAGCAAACAACTGACCAGCCTTTGGCGAAGGACAAGGTTGCCCTTTTGATAGGAAATATGAATTACCGGGAGCACCCCAAGC TCAAAGCTCCTTTGGTGGATGTGTACGAATTGACTAACTTACTGAGACAGCTGGACTTCAAAGTGGTTTCACTGTTGGATCTTACTGAATATGAGATGCG TAATGCTGTGGATGAGTTTTTACTCCTTTTAGACAAGGGAGTATATGGGTTATTATATTATGCAGGACATGGTTATGAAAATTTTGGGAACAGCTTCATG GTCCCCGTTGATGCTCCAAATCCATATAGGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAATTGATGCAAGAAAAAGAAACTGGACTTAATGTGT TCTTATTGGATATGTGTAGGAAAAGAAATGACTACGATGATACCATTCCAATCTTGGATGCACTAAAAGTCACCGCCAATATTGTGTTTGGATATGCCAC GTGTCAAGGAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAAATGGAATCTTTATGAAATTTTTAAAAGACAGATTATTAGAAGATAAGAAAATC ACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTAAGTGTCACCTTACCAAAGGCAAACAGGCTCTAGAGATTCGAAGTAGTTTATCTGAGAAGAGAG CACTTACTGATCCAATACAGGGAACAGAATATTCTGCTGAATCTCTTGTGCGGAATCTACAGTGGGCCAAGGCTCATGAACTTCCAGAAAGTATGTGTCT TAAGTTTGACTGTGGTGTTCAGATTCAATTAGGATTTGCAGCTGAGTTTTCCAATGTCATGATCATCTATACAAGTATAGTTTACAAACCACCGGAGATA ATAATGTGTGATGCCTACGTTACTGATTTTCCACTTGATCTAGATATTGATCCAAAAGATGCAAATAAAGGCACACCTGAAGAAACTGGCAGCTACTTGG TATCAAAGGATCTTCCCAAGCATTGCCTCTATACCAGACTCAGTTCACTGCAAAAATTAAAGGAACATCTAGTCTTCACAGTATGTTTATCATATCAGTA CTCAGGATTGGAAGATACTGTAGAGGACAAGCAGGAAGTGAATGTTGGGAAACCTCTCATTGCTAAATTAGACATGCATCGAGGTTTGGGAAGGAAGACT TGCTTTCAAACTTGTCTTATGTCTAATGGTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAGGGCATTATCACTCATTGCAAGACCCATTCCATG GTGTTTACCATTCACATCCTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTCATTGCAGCCGGACTCCAGATGCATTTATTTCAAGTTTCGCTCA CCATGCTTCATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAACTGATGAAATACCATTTAGTTTCTCTGACAGGCTCAGAATTTCTGAAAAATGA CCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGCCTGTGAAATAGTACTGCACTTACATAAAGTGAGACATTGTGAAAAGGCAAATTTGTATATGTA GAGAAAGAATAGTAGTAACTGTTTCATAGCAAACTTCAGGACTTTGAGATGTTGAAATTACATTATTTAATTACAGACTTCCTCTTTCTAAGATTTTGTG AATTGGTTGAATAGTTCTATACAAATGAAGTATGGAGGTGTGTATGTTTATATGTATATAACAAAATATTTTCATTGTGACCACTCTGAAGTAAGAGCAA TGGGAATGGCATTATTGTAGAATAAGTCATTGTATTTTTAACACCAGAAAGAACCTTGCCGATCACCAGGCATAACCTAATTTTATCCATGGAAGAAACA CAGAAAGGCATCTAAGTTAGAGCTGGCACCAGAACTGAGACCTCCAGAAATCTATTCCAGTATTTTTTCCACTACACAACTGCCTTCCTGACAGGTTCTG AGATAAGTGTTATGTTTGTAGATAGAGTGAAATATATTTATATATATATAAATATATACAGATACATATCTGTGTATTATCTCAAGGAATGTACAAACTT TAGTTTTTGATTATAAGGACTTCACTGCAAGTTTTAGTTAAGAGGTTTGTATATAAATCTGTTATAGAACAGGCTGAAATTTCTTGTTCATAAGATTATG AAACCACATGAGAAGTGATAAAATGTTTGTTAAAGCTAGATAGAGGTTAAGAATCAAGATATAATGGATAATTTTCATAGCTGCCTATCAGAATTTCCCA AATATTTAGCATCTTCCTTGATAATATGTATTTTCTTCTTGAATTTCACTGGCCTAATGAGATAATACTCTTATCTTTGGCTCTACCTAAAAGTTGGTTA AAAATGCAATTGGCATTAACAAGGAAAAATACTGAATTAGTAATTTTAAAAGTCTCACAAAGAAAATCCCAGGCCTAGATGGCTGCATTGTTGAATTCTG CCAAACATTAAAATTAGCACTAATTTTTTGCACACTGTTTCTAAAAGTAGGAGAGGAAAGAACACTTCCCAACTTACTCTAGGTCAGTATTACCCTGATA CTAGACTAGACATCACAAGAAAACTATAAGCCAATATTCCTTATTAATACAAACACAAAAATCATTAACAAAAATATTAGCAAACTGAATCCAGCAACCT ATAAAAAGGATTCTATATCATGACCAAGTGGAATTTATCCCAGGAATTCAAGGTTGGTTCAACATCTAAAAATCAAATAAGCTAATATACAGTCAGTTCT CATTATTCACAGTAATTATGTTCTACAGAATATTCTCCCATAAACACTGAATTAAATATGGAACAACTGCTTTTAGGAGAAAGTGTATTTGTGTATATGT GTGTATACATATGTTTATCTCACACACATTATGAGCTTGAATTCTTAATTCATCCTAGCAAATTCTACCTTATTTTACAGAAGTGAAAGTGAGGTATCAG AAGTGTTAAGTGACATGCCTGAGGCACCCCCCTAACAGGTGTCAGAGCTGAAATTCAAACCCCATCCAGCTGGCCCCGGAGCCAGAGCTTCTTGTACTAC ACAGAATTGCCCCTGCCATTTCCACCCTCCAGTCATTTCTCTATGAGACTGAAGCAGGAAGGCAGAGCATCATCTTGTTCAGCCTCAGCTGGGAACATGT GTACTGGGTGACTCAAATTTTTCACCCATTTACACATATCCACAAATGACTGCAAAAGTGCCACGGATATCAATTTGAGGGTTATAAATTTTAGCAAGTT GGTAAATTCACAAATACATAACCTTGAATAATGAGGATCAACTGTACCATATTTAATAAAGCACAAAACCCACACAGATTGTCTTATTACAGCATTTGAT AAAATCCAAAACTCTTTCATAAAAACACTCAACAAACTTAGGAATAAAAGGAATCTTCCTAGATATGATAAATATAACATCTATGAAAAGCCCACACCTA ACATTATACTTCATGGTGATAGACTGAAGGCTGAATGTTTTCCCCTTAAGATTGGGAAGAAGGACAAGGATGTTCACTCGGCACTACTTCTATTCAGCAT TGTACTTGAAGTTCTAGCCACAGCAGTTAGGTTAGGAATTCAAGGTTTGTTCAACATCTAAAAATCAAATAAGCTAATAAAGAAAAGAGGTTTATACTGC AAAAGAAGTGAAACTATATGTATTCACAGTTGATACATAGTTGTATATAGAAAATGCTAAAGAATCCATAAAAAGTAATAAATGAGTTCAACAGGT

refseq_MALT1.F1 (forward primer)
refseq_MALT1.R1 (reverse primer)
Single exon skipping

Frame 0

RGSVPRPPGAPPLCAAGAASRPGSPRQTCLIGA GSGASSSEGRAALPDLFFRPCLRGSEASGRCPGA EARDGAGGSPGSPGSPARAMSLLGDPLQALPPS AAPTGPLLAPPAGATLNRLREPLLRRLSELLDQ APEGRGWRRLAELAGSRGRLRLSCLDLEQCSLKV LEPEGSPSLCLLKLMGEKGCTVTELSDFLQAME HTEVLQLLSPPGIKITVNPESKAVLAGQFVKLC CRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVH VKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPES FQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQ CVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVD LEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNL GHPDNKEQTTDQPLAKDKVALLIGNMNYREHPK LKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMR NAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFM VPVDAPNPYRSENCLCVQNILKLMQEKETGLNV FLLDMCRKRNDYDDTIPILDALKVTANIVFGYAT CQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKI TVLLDEVAEDMGKCHLTKGKQALEIRSSLSEKR ALTDPIQGTEYSAESLVRNLQWAKAHELPESMCL KFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPEI IMCDAYVTDFPLDLDIDPKDANKGTPEETGSYL VSKDLPKHCLYTRLSSLQKLKEHLVFTVCLSYQY SGLEDTVEDKQEVNVGKPLIAKLDMHRGLGRKT CFQTCLMSNGPYQSSAATSGGAGHYHSLQDPFH GVYHSHPGNPSNVTPADSCHCSRTPDAFISSFAH HASCHFSRSNVPVETTDEIPFSFSDRLRISEK* PPCF*KLA*F*MPVK*YCTYIK*DIVKRQICIC RERIVVTVS*QTSGL*DVEITLFNYRLPLSKIL* IG*IVLYK*SMEVCMFICI*QNIFIVTTLK*EQ WEWHYCRISHCIFNTRKNLADHQA*PNFIHGRN TERHLS*SWHQN*DLQKSIPVFFPLHNCLPDRF* DKCYVCR*SEIYLYIYKYIQIHICVLSQGMYKL *FLIIRTSLQVLVKRFVYKSVIEQAEISCS*DY ETT*EVIKCLLKLDRG*ESRYNG*FS*LPIRISQ IFSIFLDNMYFLLEFHWPNEIILLSLALPKSWL KMQLALTRKNTELVILKVSQRKSQA*MAALLNS AKH*N*H*FFAHCF*K*ERKEHFPTYSRSVLP*Y *TRHHKKTISQYSLLIQTQKSLTKILAN*IQQP IKRILYHDQVEFIPGIQGWFNI*KSNKLIYSQF SLFTVIMFYRIFSHKH*IKYGTTAFRRKCICVYV CIHMFISHTL*A*ILNSS*QILPYFTEVKVRYQ KC*VTCLRHPPNRCQS*NSNPIQLAPEPELLVL HRIAPAISTLQSFLYETEAGRQSIILFSLSWEHV YWVTQIFHPFTHIHK*LQKCHGYQFEGYKF*QV GKFTNT*P*IMRINCTIFNKAQNPHRLSYYSI* *NPKLFHKNTQQT*E*KESS*I**I*HL*KAHT* HYTSW**TEG*MFSP*DWEEGQGCSLGTTSIQH CT*SSSHSS*VRNSRFVQHLKIK*ANKEKRFIL QKK*NYMYSQLIHSCI*KMLKNP*KVINEFNR

Frame 1

EAPCPAPRVPRPFARLARPAGQAPLGKPV*LGR GAELPPLRAVPRCQICSSAPASAARRRAEGAPG PRPVTGRAGAPAVRGRRRGPCRCWGTRYRPCRPR PPPRGRCSPLRPARPSTACGSRCCGGSASSWIR RPRAGAGGDWRSWRGVAGASASVA*TWSSVLLR YWSLKEAPACVC*S*WVKKVAQSQN*VISCRLWN TLKFFSFSAPQE*RLL*TQSQRQSWLDSL*NCV AGQLDILLFNISGSK*IKRFQMEIHQSLFLMQC M*KMQAFMSVELITISPLNSASGHSWMFATSQRA SREVLMASLNPSCKSVLNQLPKS*CQAAHWFYS VLLLEALFLTTSGSKMNYH*HMRPKSYTWCLMW IWNTKEPTGVMYIMIETVKIARR*KSS*MN*IIL VILIIKSKQLTSLWRRTRLPF**EI*ITGSTPS SKLLWWMCTN*LTY*DSWTSKWFHCWILLNMRC VMLWMSFYSF*TREYMGYYIMQDMVMKILGTASW SPLMLQIHIGLKIVCVYKIY*N*CKKKKLDLMC SYWICVGKEMTTMIPFQSWMH*KSPPILCLDMP RVKEQKLLKSSILDWQMESL*NF*KTDY*KIRKS LCYWMKLQKIWVSVTLPKANRL*RFEVVYLRRE HLLIQYREQNILLNLLCGIYSGPRLMNFQKVCV LSLTVVFRFN*DLQLSFPMS*SSIQV*FTNHRR* *CVMPTLLIFHLI*ILIQKMQIKAHLKKLAATW YQRIFPSIASIPDSVHCKN*RNI*SSQYVYHIS TQDWKIL*RTSRK*MLGNLSLLN*TCIEVWEGRL AFKLVLCLMVLTRVLQPPQEEQGIITHCKTHSM VFTIHILVIQVMLHQQIAVIAAGLQMHLFQVSL TMLHVILVEVMCQ*RQLMKYHLVSLTGSEFLKND LLVFES*HNFRCL*NSTALT*SETL*KGKFVYV EKE***LFHSKLQDFEMLKLHYLITDFLFLRFC ELVE*FYTNEVWRCVCLYVYNKIFSL*PL*SKSN GNGIIVE*VIVFLTPERTLPITRHNLILSMEET QKGI*VRAGTRTETSRNLFQYFFHYTTAFLTGS EISVMFVDRVKYIYIYINIYRYISVYYLKECTNF SF*L*GLHCKF*LRGLYINLL*NRLKFLVHKIM KPHEK**NVC*S*IEVKNQDIMDNFHSCLSEFP KYLASSLIICIFFLNFTGLMR*YSYLWLYLKVG* KCNWH*QGKILN**F*KSHKENPRPRWLHC*IL PNIKISTNFLHTVSKSRRGKNTSQLTLGQYYPD TRLDITRKL*ANIPY*YKHKNH*QKY*QTESSNL *KGFYIMTKWNLSQEFKVGSTSKNQIS*YTVSS HYSQ*LCSTEYSPINTELNMEQLLLGESVFVYM CVYICLSHTHYELEFLIHPSKFYLILQK*K*GIR SVK*HA*GTPLTGVRAEIQTPSSWPRSQSFLYY TELPLPFPPSSHFSMRLKQEGRASSCSASAGNM CTG*LKFFTHLHISTNDCKSATDINLRVINFSKL VNSQIHNLE**GSTVPYLIKHKTHTDCLITAFD KIQNSFIKTLNKLRNKRNLPRYDKYNIYEKPTP NIILHGDRLKAECFPLKIGKKDKDVHSALLLFSI VLEVLATAVRLGIQGLFNI*KSNKLIKKRGLYC KRSETICIHS*YIVVYRKC*RIHKK**MSSTG

Frame 2

RLRAPPPGCPAPLRGWRGQQARLPSANLSNWGG ERSFLL*GPCRAARFVLPPLPPRLGGERKVPRG RGP*RGGREPRQSGVAGEGHVAVGGPATGPAAL GRPHGAAARPSGRRDPQPPAGAAAAEAQRAPGSG ARGPGLEETGGAGGESRAPPPQLPRPGAVFS*G TGA*RKPQPVSAEVNG*KRLHSHRIE*FPAGYG TH*SSSASQPPRNKDYCKPRVKGSLGWTVCETVL PGNWTSFCSISVVQNE*RDSKWKYIRAYF*CSA CKRCRLLCLSS**QFHL*IQPVVTAGCLRHPRE LPEKC*WRL*IQVANLC*TNFPKADARQHIGFTV CCCWKPYSSLPVVQK*ITINT*DQKAIHGALCG FGTPRNLLVSCI**SRQSR*QEGRNHHR*IK*S WSS***RANN*PAFGEGQGCPFDRKYELPGAPQA QSSFGGCVRID*LTETAGLQSGFTVGSY*I*DA *CCG*VFTPFRQGSIWVIILCRTWL*KFWEQLH GPR*CSKSI*V*KLSVCTKYTEIDARKRNWT*CV LIGYV*EKK*LR*YHSNLGCTKSHRQYCVWICH VSRSRSF*NPAFWIGKWNLYEIFKRQIIRR*EN HCVTG*SCRRYG*VSPYQRQTGSRDSK*FI*EES TY*SNTGNRIFC*ISCAESTVGQGS*TSRKYVS *V*LWCSDSIRICS*VFQCHDHLYKYSLQTTGD NNV*CLRY*FST*SRY*SKRCK*RHT*RNWQLLG IKGSSQALPLYQTQFTAKIKGTSSLHSMFIISV LRIGRYCRGQAGSECWETSHC*IRHASRFGKED LLSNLSYV*WSLPEFCSHLRRSRALSLIARPIPW CLPFTSW*SK*CYTSR*LSLQPDSRCIYFKFRS PCFMSF**K*CASRDN**NTI*FL*QAQNF*KM TSLFLKVSIILDACEIVLHLHKVRHCEKANLYM* RKNSSNCFIANFRTLRC*NYII*LQTSSF*DFV NWLNSSIQMKYGGVYVYMYITKYFHCDHSEVRA MGMALL*NKSLYF*HQKEPCRSPGIT*FYPWKKH RKASKLELAPELRPPEIYSSIFSTTQLPS*QVL R*VLCL*IE*NIFIYI*IYTDTYLCIISRNVQT LVFDYKDFTASFS*EVCI*ICYRTG*NFLFIRL* NHMRSDKMFVKAR*RLRIKI*WIIFIAAYQNFP NI*HLP**YVFSS*ISLA**DNTLIFGST*KLV KNAIGINKEKY*ISNFKSLTKKIPGLDGCIVEFC QTLKLALIFCTLFLKVGEERTLPNLL*VSITLI LD*TSQENYKPIFLINTNTKIINKNISKLNPAT YKKDSIS*PSGIYPRNSRLVQHLKIK*ANIQSVL IIHSNYVLQNILP*TLN*IWNNCF*EKVYLCIC VYTYVYLTHIMSLNS*FILANSTLFYRSESEVS EVLSDMPEAPP*QVSELKFKPHPAGPGARASCTT QNCPCHFHPPVISL*D*SRKAEHHLVQPQLGTC VLGDSNFSPIYTYPQMTAKVPRISI*GL*ILAS W*IHKYITLNNEDQLYHI**STKPTQIVLLQHLI KSKTLS*KHSTNLGIKGIFLDMINITSMKSPHL TLYFMVID*RLNVFPLRLGRRTRMFTRHYFYSA LYLKF*PQQLG*EFKVCSTSKNQIS**RKEVYTA KEVKLYVFTVDT*LYIENAKESIKSNK*VQQ

Sequence NM_006785

CGAGGCTCCGTGCCCCGCCCCCCGGGTGCCCCGCCCCTTTGCGCGGCTGGCGCGGCCAGCAGGCCAGGCTCCCCTCGGCAAACCTGTCTAATTGGGGCGG GGAGCGGAGCTTCCTCCTCTGAGGGCCGTGCCGCGCTGCCAGATTTGTTCTTCCGCCCCTGCCTCCGCGGCTCGGAGGCGAGCGGAAGGTGCCCCGGGGC CGAGGCCCGTGACGGGGCGGGCGGGAGCCCCGGCAGTCCGGGGTCGCCGGCGAGGGCCATGTCGCTGTTGGGGGACCCGCTACAGGCCCTGCCGCCCTCG GCCGCCCCCACGGGGCCGCTGCTCGCCCCTCCGGCCGGCGCGACCCTCAACCGCCTGCGGGAGCCGCTGCTGCGGAGGCTCAGCGAGCTCCTGGATCAGG CGCCCGAGGGCCGGGGCTGGAGGAGACTGGCGGAGCTGGCGGGGAGTCGCGGGCGCCTCCGCCTCAGTTGCCTAGACCTGGAGCAGTGTTCTCTTAAGGT ACTGGAGCCTGAAGGAAGCCCCAGCCTGTGTCTGCTGAAGTTAATGGGTGAAAAAGGTTGCACAGTCACAGAATTGAGTGATTTCCTGCAGGCTATGGAA CACACTGAAGTTCTTCAGCTTCTCAGCCCCCCAGGAATAAAGATTACTGTAAACCCAGAGTCAAAGGCAGTCTTGGCTGGACAGTTTGTGAAACTGTGTT GCCGGGCAACTGGACATCCTTTTGTTCAATATCAGTGGTTCAAAATGAATAAAGAGATTCCAAATGGAAATACATCAGAGCTTATTTTTAATGCAGTGCA TGTAAAAGATGCAGGCTTTTATGTCTGTCGAGTTAATAACAATTTCACCTTTGAATTCAGCCAGTGGTCACAGCTGGATGTTTGCGACATCCCAGAGAGC TTCCAGAGAAGTGTTGATGGCGTCTCTGAATCCAAGTTGCAAATCTGTGTTGAACCAACTTCCCAAAAGCTGATGCCAGGCAGCACATTGGTTTTACAGT GTGTTGCTGTTGGAAGCCCTATTCCTCACTACCAGTGGTTCAAAAATGAATTACCATTAACACATGAGACCAAAAAGCTATACATGGTGCCTTATGTGGA TTTGGAACACCAAGGAACCTACTGGTGTCATGTATATAATGATCGAGACAGTCAAGATAGCAAGAAGGTAGAAATCATCATAGGAAGAACAGATGAGGCA GTGGAGTGCACTGAAGATGAATTAAATAATCTTGGTCATCCTGATAATAAAGAGCAAACAACTGACCAGCCTTTGGCGAAGGACAAGGTTGCCCTTTTGA TAGGAAATATGAATTACCGGGAGCACCCCAAGCTCAAAGCTCCTTTGGTGGATGTGTACGAATTGACTAACTTACTGAGACAGCTGGACTTCAAAGTGGT TTCACTGTTGGATCTTACTGAATATGAGATGCGTAATGCTGTGGATGAGTTTTTACTCCTTTTAGACAAGGGAGTATATGGGTTATTATATTATGCAGGA CATGGTTATGAAAATTTTGGGAACAGCTTCATGGTCCCCGTTGATGCTCCAAATCCATATAGGTCTGAAAATTGTCTGTGTGTACAAAATATACTGAAAT TGATGCAAGAAAAAGAAACTGGACTTAATGTGTTCTTATTGGATATGTGTAGGAAAAGAAATGACTACGATGATACCATTCCAATCTTGGATGCACTAAA AGTCACCGCCAATATTGTGTTTGGATATGCCACGTGTCAAGGAGCAGAAGCTTTTGAAATCCAGCATTCTGGATTGGCAAATGGAATCTTTATGAAATTT TTAAAAGACAGATTATTAGAAGATAAGAAAATCACTGTGTTACTGGATGAAGTTGCAGAAGATATGGGTAAGTGTCACCTTACCAAAGGCAAACAGGCTC TAGAGATTCGAAGTAGTTTATCTGAGAAGAGAGCACTTACTGATCCAATACAGGGAACAGAATATTCTGCTGAATCTCTTGTGCGGAATCTACAGTGGGC CAAGGCTCATGAACTTCCAGAAAGTATGTGTCTTAAGTTTGACTGTGGTGTTCAGATTCAATTAGGATTTGCAGCTGAGTTTTCCAATGTCATGATCATC TATACAAGTATAGTTTACAAACCACCGGAGATAATAATGTGTGATGCCTACGTTACTGATTTTCCACTTGATCTAGATATTGATCCAAAAGATGCAAATA AAGGCACACCTGAAGAAACTGGCAGCTACTTGGTATCAAAGGATCTTCCCAAGCATTGCCTCTATACCAGACTCAGTTCACTGCAAAAATTAAAGGAACA TCTAGTCTTCACAGTATGTTTATCATATCAGTACTCAGGATTGGAAGATACTGTAGAGGACAAGCAGGAAGTGAATGTTGGGAAACCTCTCATTGCTAAA TTAGACATGCATCGAGGTTTGGGAAGGAAGACTTGCTTTCAAACTTGTCTTATGTCTAATGGTCCTTACCAGAGTTCTGCAGCCACCTCAGGAGGAGCAG GGCATTATCACTCATTGCAAGACCCATTCCATGGTGTTTACCATTCACATCCTGGTAATCCAAGTAATGTTACACCAGCAGATAGCTGTCATTGCAGCCG GACTCCAGATGCATTTATTTCAAGTTTCGCTCACCATGCTTCATGTCATTTTAGTAGAAGTAATGTGCCAGTAGAGACAACTGATGAAATACCATTTAGT TTCTCTGACAGGCTCAGAATTTCTGAAAAATGACCTCCTTGTTTTTGAAAGTTAGCATAATTTTAGATGCCTGTGAAATAGTACTGCACTTACATAAAGT GAGACATTGTGAAAAGGCAAATTTGTATATGTAGAGAAAGAATAGTAGTAACTGTTTCATAGCAAACTTCAGGACTTTGAGATGTTGAAATTACATTATT TAATTACAGACTTCCTCTTTCTAAGATTTTGTGAATTGGTTGAATAGTTCTATACAAATGAAGTATGGAGGTGTGTATGTTTATATGTATATAACAAAAT ATTTTCATTGTGACCACTCTGAAGTAAGAGCAATGGGAATGGCATTATTGTAGAATAAGTCATTGTATTTTTAACACCAGAAAGAACCTTGCCGATCACC AGGCATAACCTAATTTTATCCATGGAAGAAACACAGAAAGGCATCTAAGTTAGAGCTGGCACCAGAACTGAGACCTCCAGAAATCTATTCCAGTATTTTT TCCACTACACAACTGCCTTCCTGACAGGTTCTGAGATAAGTGTTATGTTTGTAGATAGAGTGAAATATATTTATATATATATAAATATATACAGATACAT ATCTGTGTATTATCTCAAGGAATGTACAAACTTTAGTTTTTGATTATAAGGACTTCACTGCAAGTTTTAGTTAAGAGGTTTGTATATAAATCTGTTATAG AACAGGCTGAAATTTCTTGTTCATAAGATTATGAAACCACATGAGAAGTGATAAAATGTTTGTTAAAGCTAGATAGAGGTTAAGAATCAAGATATAATGG ATAATTTTCATAGCTGCCTATCAGAATTTCCCAAATATTTAGCATCTTCCTTGATAATATGTATTTTCTTCTTGAATTTCACTGGCCTAATGAGATAATA CTCTTATCTTTGGCTCTACCTAAAAGTTGGTTAAAAATGCAATTGGCATTAACAAGGAAAAATACTGAATTAGTAATTTTAAAAGTCTCACAAAGAAAAT CCCAGGCCTAGATGGCTGCATTGTTGAATTCTGCCAAACATTAAAATTAGCACTAATTTTTTGCACACTGTTTCTAAAAGTAGGAGAGGAAAGAACACTT CCCAACTTACTCTAGGTCAGTATTACCCTGATACTAGACTAGACATCACAAGAAAACTATAAGCCAATATTCCTTATTAATACAAACACAAAAATCATTA ACAAAAATATTAGCAAACTGAATCCAGCAACCTATAAAAAGGATTCTATATCATGACCAAGTGGAATTTATCCCAGGAATTCAAGGTTGGTTCAACATCT AAAAATCAAATAAGCTAATATACAGTCAGTTCTCATTATTCACAGTAATTATGTTCTACAGAATATTCTCCCATAAACACTGAATTAAATATGGAACAAC TGCTTTTAGGAGAAAGTGTATTTGTGTATATGTGTGTATACATATGTTTATCTCACACACATTATGAGCTTGAATTCTTAATTCATCCTAGCAAATTCTA CCTTATTTTACAGAAGTGAAAGTGAGGTATCAGAAGTGTTAAGTGACATGCCTGAGGCACCCCCCTAACAGGTGTCAGAGCTGAAATTCAAACCCCATCC AGCTGGCCCCGGAGCCAGAGCTTCTTGTACTACACAGAATTGCCCCTGCCATTTCCACCCTCCAGTCATTTCTCTATGAGACTGAAGCAGGAAGGCAGAG CATCATCTTGTTCAGCCTCAGCTGGGAACATGTGTACTGGGTGACTCAAATTTTTCACCCATTTACACATATCCACAAATGACTGCAAAAGTGCCACGGA TATCAATTTGAGGGTTATAAATTTTAGCAAGTTGGTAAATTCACAAATACATAACCTTGAATAATGAGGATCAACTGTACCATATTTAATAAAGCACAAA ACCCACACAGATTGTCTTATTACAGCATTTGATAAAATCCAAAACTCTTTCATAAAAACACTCAACAAACTTAGGAATAAAAGGAATCTTCCTAGATATG ATAAATATAACATCTATGAAAAGCCCACACCTAACATTATACTTCATGGTGATAGACTGAAGGCTGAATGTTTTCCCCTTAAGATTGGGAAGAAGGACAA GGATGTTCACTCGGCACTACTTCTATTCAGCATTGTACTTGAAGTTCTAGCCACAGCAGTTAGGTTAGGAATTCAAGGTTTGTTCAACATCTAAAAATCA AATAAGCTAATAAAGAAAAGAGGTTTATACTGCAAAAGAAGTGAAACTATATGTATTCACAGTTGATACATAGTTGTATATAGAAAATGCTAAAGAATCC ATAAAAAGTAATAAATGAGTTCAACAGGT

refseq_MALT1.F1 (forward primer)
refseq_MALT1.R1 (reverse primer)
Single exon skipping

Frame 0

RGSVPRPPGAPPLCAAGAASRPGSPRQTCLIGA GSGASSSEGRAALPDLFFRPCLRGSEASGRCPGA EARDGAGGSPGSPGSPARAMSLLGDPLQALPPS AAPTGPLLAPPAGATLNRLREPLLRRLSELLDQ APEGRGWRRLAELAGSRGRLRLSCLDLEQCSLKV LEPEGSPSLCLLKLMGEKGCTVTELSDFLQAME HTEVLQLLSPPGIKITVNPESKAVLAGQFVKLC CRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVH VKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPES FQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQ CVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVD LEHQGTYWCHVYNDRDSQDSKKVEIIIGRTDEA VECTEDELNNLGHPDNKEQTTDQPLAKDKVALL IGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVV SLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAG HGYENFGNSFMVPVDAPNPYRSENCLCVQNILK LMQEKETGLNVFLLDMCRKRNDYDDTIPILDALK VTANIVFGYATCQGAEAFEIQHSGLANGIFMKF LKDRLLEDKKITVLLDEVAEDMGKCHLTKGKQA LEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWA KAHELPESMCLKFDCGVQIQLGFAAEFSNVMII YTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDAN KGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEH LVFTVCLSYQYSGLEDTVEDKQEVNVGKPLIAK LDMHRGLGRKTCFQTCLMSNGPYQSSAATSGGA GHYHSLQDPFHGVYHSHPGNPSNVTPADSCHCSR TPDAFISSFAHHASCHFSRSNVPVETTDEIPFS FSDRLRISEK*PPCF*KLA*F*MPVK*YCTYIK *DIVKRQICICRERIVVTVS*QTSGL*DVEITLF NYRLPLSKIL*IG*IVLYK*SMEVCMFICI*QN IFIVTTLK*EQWEWHYCRISHCIFNTRKNLADH QA*PNFIHGRNTERHLS*SWHQN*DLQKSIPVFF PLHNCLPDRF*DKCYVCR*SEIYLYIYKYIQIH ICVLSQGMYKL*FLIIRTSLQVLVKRFVYKSVI EQAEISCS*DYETT*EVIKCLLKLDRG*ESRYNG *FS*LPIRISQIFSIFLDNMYFLLEFHWPNEII LLSLALPKSWLKMQLALTRKNTELVILKVSQRK SQA*MAALLNSAKH*N*H*FFAHCF*K*ERKEHF PTYSRSVLP*Y*TRHHKKTISQYSLLIQTQKSL TKILAN*IQQPIKRILYHDQVEFIPGIQGWFNI *KSNKLIYSQFSLFTVIMFYRIFSHKH*IKYGTT AFRRKCICVYVCIHMFISHTL*A*ILNSS*QIL PYFTEVKVRYQKC*VTCLRHPPNRCQS*NSNPI QLAPEPELLVLHRIAPAISTLQSFLYETEAGRQS IILFSLSWEHVYWVTQIFHPFTHIHK*LQKCHG YQFEGYKF*QVGKFTNT*P*IMRINCTIFNKAQ NPHRLSYYSI**NPKLFHKNTQQT*E*KESS*I* *I*HL*KAHT*HYTSW**TEG*MFSP*DWEEGQ GCSLGTTSIQHCT*SSSHSS*VRNSRFVQHLKI K*ANKEKRFILQKK*NYMYSQLIHSCI*KMLKNP *KVINEFNR

Frame 1

EAPCPAPRVPRPFARLARPAGQAPLGKPV*LGR GAELPPLRAVPRCQICSSAPASAARRRAEGAPG PRPVTGRAGAPAVRGRRRGPCRCWGTRYRPCRPR PPPRGRCSPLRPARPSTACGSRCCGGSASSWIR RPRAGAGGDWRSWRGVAGASASVA*TWSSVLLR YWSLKEAPACVC*S*WVKKVAQSQN*VISCRLWN TLKFFSFSAPQE*RLL*TQSQRQSWLDSL*NCV AGQLDILLFNISGSK*IKRFQMEIHQSLFLMQC M*KMQAFMSVELITISPLNSASGHSWMFATSQRA SREVLMASLNPSCKSVLNQLPKS*CQAAHWFYS VLLLEALFLTTSGSKMNYH*HMRPKSYTWCLMW IWNTKEPTGVMYIMIETVKIARR*KSS*EEQMRQ WSALKMN*IILVILIIKSKQLTSLWRRTRLPF* *EI*ITGSTPSSKLLWWMCTN*LTY*DSWTSKW FHCWILLNMRCVMLWMSFYSF*TREYMGYYIMQD MVMKILGTASWSPLMLQIHIGLKIVCVYKIY*N *CKKKKLDLMCSYWICVGKEMTTMIPFQSWMH* KSPPILCLDMPRVKEQKLLKSSILDWQMESL*NF *KTDY*KIRKSLCYWMKLQKIWVSVTLPKANRL *RFEVVYLRREHLLIQYREQNILLNLLCGIYSG PRLMNFQKVCVLSLTVVFRFN*DLQLSFPMS*SS IQV*FTNHRR**CVMPTLLIFHLI*ILIQKMQI KAHLKKLAATWYQRIFPSIASIPDSVHCKN*RN I*SSQYVYHISTQDWKIL*RTSRK*MLGNLSLLN *TCIEVWEGRLAFKLVLCLMVLTRVLQPPQEEQ GIITHCKTHSMVFTIHILVIQVMLHQQIAVIAA GLQMHLFQVSLTMLHVILVEVMCQ*RQLMKYHLV SLTGSEFLKNDLLVFES*HNFRCL*NSTALT*S ETL*KGKFVYVEKE***LFHSKLQDFEMLKLHY LITDFLFLRFCELVE*FYTNEVWRCVCLYVYNKI FSL*PL*SKSNGNGIIVE*VIVFLTPERTLPIT RHNLILSMEETQKGI*VRAGTRTETSRNLFQYF FHYTTAFLTGSEISVMFVDRVKYIYIYINIYRYI SVYYLKECTNFSF*L*GLHCKF*LRGLYINLL* NRLKFLVHKIMKPHEK**NVC*S*IEVKNQDIM DNFHSCLSEFPKYLASSLIICIFFLNFTGLMR*Y SYLWLYLKVG*KCNWH*QGKILN**F*KSHKEN PRPRWLHC*ILPNIKISTNFLHTVSKSRRGKNT SQLTLGQYYPDTRLDITRKL*ANIPY*YKHKNH* QKY*QTESSNL*KGFYIMTKWNLSQEFKVGSTS KNQIS*YTVSSHYSQ*LCSTEYSPINTELNMEQ LLLGESVFVYMCVYICLSHTHYELEFLIHPSKFY LILQK*K*GIRSVK*HA*GTPLTGVRAEIQTPS SWPRSQSFLYYTELPLPFPPSSHFSMRLKQEGR ASSCSASAGNMCTG*LKFFTHLHISTNDCKSATD INLRVINFSKLVNSQIHNLE**GSTVPYLIKHK THTDCLITAFDKIQNSFIKTLNKLRNKRNLPRY DKYNIYEKPTPNIILHGDRLKAECFPLKIGKKDK DVHSALLLFSIVLEVLATAVRLGIQGLFNI*KS NKLIKKRGLYCKRSETICIHS*YIVVYRKC*RI HKK**MSSTG

Frame 2

RLRAPPPGCPAPLRGWRGQQARLPSANLSNWGG ERSFLL*GPCRAARFVLPPLPPRLGGERKVPRG RGP*RGGREPRQSGVAGEGHVAVGGPATGPAAL GRPHGAAARPSGRRDPQPPAGAAAAEAQRAPGSG ARGPGLEETGGAGGESRAPPPQLPRPGAVFS*G TGA*RKPQPVSAEVNG*KRLHSHRIE*FPAGYG TH*SSSASQPPRNKDYCKPRVKGSLGWTVCETVL PGNWTSFCSISVVQNE*RDSKWKYIRAYF*CSA CKRCRLLCLSS**QFHL*IQPVVTAGCLRHPRE LPEKC*WRL*IQVANLC*TNFPKADARQHIGFTV CCCWKPYSSLPVVQK*ITINT*DQKAIHGALCG FGTPRNLLVSCI**SRQSR*QEGRNHHRKNR*G SGVH*R*IK*SWSS***RANN*PAFGEGQGCPFD RKYELPGAPQAQSSFGGCVRID*LTETAGLQSG FTVGSY*I*DA*CCG*VFTPFRQGSIWVIILCR TWL*KFWEQLHGPR*CSKSI*V*KLSVCTKYTEI DARKRNWT*CVLIGYV*EKK*LR*YHSNLGCTK SHRQYCVWICHVSRSRSF*NPAFWIGKWNLYEI FKRQIIRR*ENHCVTG*SCRRYG*VSPYQRQTGS RDSK*FI*EESTY*SNTGNRIFC*ISCAESTVG QGS*TSRKYVS*V*LWCSDSIRICS*VFQCHDH LYKYSLQTTGDNNV*CLRY*FST*SRY*SKRCK* RHT*RNWQLLGIKGSSQALPLYQTQFTAKIKGT SSLHSMFIISVLRIGRYCRGQAGSECWETSHC* IRHASRFGKEDLLSNLSYV*WSLPEFCSHLRRSR ALSLIARPIPWCLPFTSW*SK*CYTSR*LSLQP DSRCIYFKFRSPCFMSF**K*CASRDN**NTI* FL*QAQNF*KMTSLFLKVSIILDACEIVLHLHKV RHCEKANLYM*RKNSSNCFIANFRTLRC*NYII *LQTSSF*DFVNWLNSSIQMKYGGVYVYMYITK YFHCDHSEVRAMGMALL*NKSLYF*HQKEPCRSP GIT*FYPWKKHRKASKLELAPELRPPEIYSSIF STTQLPS*QVLR*VLCL*IE*NIFIYI*IYTDT YLCIISRNVQTLVFDYKDFTASFS*EVCI*ICYR TG*NFLFIRL*NHMRSDKMFVKAR*RLRIKI*W IIFIAAYQNFPNI*HLP**YVFSS*ISLA**DN TLIFGST*KLVKNAIGINKEKY*ISNFKSLTKKI PGLDGCIVEFCQTLKLALIFCTLFLKVGEERTL PNLL*VSITLILD*TSQENYKPIFLINTNTKII NKNISKLNPATYKKDSIS*PSGIYPRNSRLVQHL KIK*ANIQSVLIIHSNYVLQNILP*TLN*IWNN CF*EKVYLCICVYTYVYLTHIMSLNS*FILANS TLFYRSESEVSEVLSDMPEAPP*QVSELKFKPHP AGPGARASCTTQNCPCHFHPPVISL*D*SRKAE HHLVQPQLGTCVLGDSNFSPIYTYPQMTAKVPR ISI*GL*ILASW*IHKYITLNNEDQLYHI**STK PTQIVLLQHLIKSKTLS*KHSTNLGIKGIFLDM INITSMKSPHLTLYFMVID*RLNVFPLRLGRRT RMFTRHYFYSALYLKF*PQQLG*EFKVCSTSKNQ IS**RKEVYTAKEVKLYVFTVDT*LYIENAKES IKSNK*VQQ