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Sequences

Sequence NM_001017404

ATGCGCTTGGAGGGAGAGGGCCGCTCAGCGAGGGCGGGACAGAACCTCTCCCGGGCTGGGAGTGCACGGCGCGGTGCGCCCAGGGACCTCAGCATGAACA ACCTCACAGAGCTTCAGCCTGGCCTCTTCCACCACCTGCGCTTCTTGGAGGAGCTGCGTCTCTCTGGGAACCATCTCTCACACATCCCAGGACAAGCATT CTCTGGTCTCTACAGCCTGAAAATCCTGATGCTGCAGAACAATCAGCTGGGAGGAATCCCCGCAGAGGCGCTGTGGGAGCTGCCGAGCCTGCAGTCGCTA GACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTGGCCATCCGGACCCTGGGCAGACTGCAGGAACTGGGGTTCCATAACAACAACATCAAGGCCATCC CAGAAAAGGCCTTCATGGGGAACCCTCTGCTACAGACGATACACTTTTATGATAACCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGCCTAA ACTCCACACACTATCTCTGAATGGTGCCATGGACATCCAGGAGTTTCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGCAGGC ATCCGGCTGCTCCCATCGGGGATGTGCCAACAGCTGCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCACAGGT GTCAGAAATTGGAGGAAATCGGCCTCCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAAGCCCTGGATCTTAG CTGGAACGCCATCCGGTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGACAACCAGCTGACCACACTGCCCCTG GCTGGACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCCAAGGACAGTTTCCCAAAACTGAGGATCCTGGAGG TGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCCTCTGGGCAGTGGGAGGCTGAAGACCTTCACCTTGATGATGAGGA GTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAACCACTATGACCAGGACCTGGATGAGCTCCAGCTGGAGATGGAGGACTCAAAGCCA CACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCCTTCAAGCCCTGTGAGTACCTCTTTGAAAGCTGGGGCATCCGCCTGGCCGTGTGGGCCATCGTGT TGCTCTCCGTGCTCTGCAATGGACTGGTGCTGCTGACCGTGTTCGCTGGCGGGCCTGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTGCAGG CGCCAACACCTTGACTGGCATTTCCTGTGGCCTTCTAGCCTCAGTCGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGACGGGG CTAGGCTGCCGGGCCACTGGCTTCCTGGCAGTACTTGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTCTCCT GTGTCCGGGCCTATGGGAAGTCCCCCTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCCGCGCTGCCCCTGGC CTCAGTGGGAGAATACGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGCTTCACCGTGGCCCTGGTGATGATG AACTCCTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGCGACTTTGAGGCCGTGTGGGACTGCGCCATGGTGA GGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTCCTCAGCTTTGCCTCCATGCTGGGCCTCTTCCCTGTCACGCCCGA GGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGCCTCAACCCACTGCTGTACCTGCTCTTCAACCCCCACTTCCGGGATGACCTTCGG CGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTAGCCTATGCTGCGGCCGGGGAGCTGGAGAAGAGCTCCTGTGATTCTACCCAGGCCCTGGTAGCCT TCTCTGATGTGGATCTCATTCTGGAAGCTTCTGAAGCTGGGCGGCCCCCTGGGCTGGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTCAGCA GCCAGGGGCCCCCAGGCTGGAGGGCAGCCATTGTGTAGAGCCAGAGGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCTGAGG GCAGAGGGATCTACGCCAGCAGGTGGAGGCTTGTCAGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTCCCCA TTCTTCTCTTCCCCTCTCTTCCCTTTCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCAGTGTGATCTATAGC AGGATGGCCCAGTCCCTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCTTTCCCTTGGCCTTCCTCAGCTTCA CCTTGATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTGCTTAAGGGAAATGAGGGAAGTAAAGACAGTGAAG GGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTGGAAGGTGATTTCCCGTGTGACTCATGGATAGGATACAAAATGTG TTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCCTATTAAAATAAGCTTTGGAAGAGATTACACATGATGTCTTTTTCTTAGAGATTC ACAGTGCATGTTAGTGTAATAAAGAGATAAGTCCTACAGTA

refseq_LGR6.F1 (forward primer)
refseq_LGR6.R1 (reverse primer)
Multiple exon skipping

Frame 0

MRLEGEGRSARAGQNLSRAGSARRGAPRDLSMN NLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAF SGLYSLKILMLQNNQLGGIPAEALWELPSLQSL DLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAI PEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPK LHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG IRLLPSGMCQQLPRLRVLELSHNQIEELPSLHR CQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLS WNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPL AGLGGLMHLKLKGNLALSQAFSKDSFPKLRILE VPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEE SSKRPLGLLARQAENHYDQDLDELQLEMEDSKP HPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIV LLSVLCNGLVLLTVFAGGPVPLPPVKFVVGAIAG ANTLTGISCGLLASVDALTFGQFSEYGARWETG LGCRATGFLAVLGSEASVLLLTLAAVQCSVSVS CVRAYGKSPSLGSVRAGVLGCLALAGLAAALPLA SVGEYGASPLCLPYAPPEGQPAALGFTVALVMM NSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMV RHVAWLIFADGLLYCPVAFLSFASMLGLFPVTPE AVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLR RLRPRAGDSGPLAYAAAGELEKSSCDSTQALVA FSDVDLILEASEAGRPPGLETYGFPSVTLISCQQ PGAPRLEGSHCVEPEGNHFGNPQPSMDGELLLR AEGSTPAGGGLSGGGGFQPSGLAFASHV*ISLP ILLFPSLPFPLSPSVNDGCF*NKYNQNSAV*SIA GWPSPWLH*SPLSCDHHQRVPLGLAFPWPSSAS P*YWASSLSCLKLWTRDLDFCLLKGNEGSKDSE GVEG*SGHSGQGDLTEKGLEGDFPCDSWIGYKMC SMYH*S*HMPCIKTSY*NKLWKRLHMMSFS*RF TVHVSVIKR*VLQ

Frame 1

CAWRERAAQRGRDRTSPGLGVHGAVRPGTSA*T TSQSFSLASSTTCASWRSCVSLGTISHTSQDKH SLVSTA*KS*CCRTISWEESPQRRCGSCRACSR* T*IITSCRSSLWPSGPWADCRNWGSITTTSRPS QKRPSWGTLCYRRYTFMITQSSLWEDRHSSTCL NSTHYL*MVPWTSRSFQISKAPPAWRS*P*PAQA SGCSHRGCANSCPGSESWNCLTIKLRSCPACTG VRNWRKSASNTTASGKLELTPSAS*APCKPWIL AGTPSGPSTPRPSPPCTPWSSWT*QTTS*PHCPW LDLGA*CI*SSKGTLLSPRPSPRTVSQN*GSWR CLMPTSAVPMGCVPASSRPLGSGRLKTFTLMMR SLQKGPWASLPDKQRTTMTRTWMSSSWRWRTQSH TPVSSVALLQAPSSPVSTSLKAGASAWPCGPSC CSPCSAMDWCC*PCSLAGLSPCPRSSLW*VRLQ APTP*LAFPVAF*PQSMP*PLVSSLSTEPAGRRG *AAGPLASWQYLGRRHRCCCSLWPQCSAASPSP VSGPMGSPPPWAAFEQGS*AAWHWQGWPPRCPW PQWENTGPPHSACPTRHLRVSQQPWASPWPW*** TPSVSWSWPVPTSNCTVTCRGATLRPCGTAPW* GTWPGSSSQTGSSTVPWPSSALPPCWASSLSRP RPSSLSCWWCCPCLPASTHCCTCSSTPTSGMTFG GFGPAQGTQGP*PMLRPGSWRRAPVILPRPW*P SLMWISFWKLLKLGGPLGWRPMASPQ*PSSPVS SQGPPGWRAAIV*SQRGTTLGTPNPPWMENCC*G QRDLRQQVEACQGVAAFSPLAWPLLHTCKYPSP FFSSPLFPFLSPPR*MMAASKTNTTKTQQCDL* QDGPVPGSTDHLSPVTITNGCLLAWLSLGLPQLH LDTGPLPCHV*SCGPETWTFVCLREMREVKTVK GWRVDQGTVDRETSQRKAWKVISRVTHG*DTKC VPCTINLDICHA*RLPIKISFGRDYT*CLFLRDS QCMLV**RDKSYS

Frame 2

ALGGRGPLSEGGTEPLPGWECTARCAQGPQHEQ PHRASAWPLPPPALLGGAASLWEPSLTHPRTSI LWSLQPENPDAAEQSAGRNPRRGAVGAAEPAVA RPEL*QAAGVPCGHPDPGQTAGTGVP*QQHQGHP RKGLHGEPSATDDTLL**PNPVCGKIGIPVPA* TPHTISEWCHGHPGVSRSQRHHQPGDPDPDPRR HPAAPIGDVPTAAQAPSPGTVSQSN*GAAQPAQV SEIGGNRPPTQPHLGNWS*HLQPAELPASPGS* LERHPVHPPRGLLHPALPGQAGPDRQPADHTAP GWTWGLDASEAQREPCSLPGLLQGQFPKTEDPGG ALCLPVLSLWDVCQLLQGLWAVGG*RPSP***G VFKKAPGPPCQTSREPL*PGPG*APAGDGGLKA TPQCPV*PYSRPLQAL*VPL*KLGHPPGRVGHRV ALRALQWTGAADRVRWRACPPAPGQVCGRCDCR RQHLDWHFLWPSSLSRCPDLWSVL*VRSPLGDG ARLPGHWLPGSTWVGGIGAAAHSGRSAVQRLRLL CPGLWEVPLPGQRSSRGPRLPGTGRAGRRAAPG LSGRIRGLPTLPALRAT*GSASSPGLHRGPGDD ELLLFPGRGRCLHQTVL*PAAGRL*GRVGLRHGE ARGLAHLRRRAPLLSRGLPQLCLHAGPLPCHAR GRQVCPAGGAAPACLPQPTAVPALQPPLPG*PS AASAPRRGLRAPSLCCGRGAGEELL*FYPGPGSL L*CGSHSGSF*SWAAPWAGDLWLPLSDPHLLSA ARGPQAGGQPLCRARGEPLWEPPTLHGWRTAAE GRGIYASRWRLVRGWRLSALWLGLCFTRVNIPPH SSLPLSSLSSLPLGE*WLLLKQIQPKLSSVIYS RMAQSLAPLITSLL*PSPTGASWPGFPLAFLSF TLILGLFLVMSEAVDQRPGLLSA*GK*GK*RQ*R GGGLIRAQWTGRPHRERPGR*FPV*LMDRIQNV FHVPLILTYAMHKDFLLK*ALEEITHDVFFLEI HSAC*CNKEISPTV

Sequence NM_021636

TGAAAGGCGGTTGTGGTGCAAAGGAAAACCCACAGGCCAAGGAATGGGAAGACCAAGGTTGACACTTGTTTGTCAAGTGTCAATAATCATCTCTGCCCGG GACCTCAGCATGAACAACCTCACAGAGCTTCAGCCTGGCCTCTTCCACCACCTGCGCTTCTTGGAGGAGCTGCGTCTCTCTGGGAACCATCTCTCACACA TCCCAGGACAAGCATTCTCTGGTCTCTACAGCCTGAAAATCCTGATGCTGCAGAACAATCAGCTGGGAGGAATCCCCGCAGAGGCGCTGTGGGAGCTGCC GAGCCTGCAGTCGCTGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTGTCCTCCCTCCGCCACCTCTGGCTGGACGAC AATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATGACCCTGGCCCTCAACCGCATCAGCCACATCCCCGACTACG CGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGCATCCAGCATCTGGGGACCCACAGCTTCGAGGGGCTGCACAATCTGGAGAC ACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTGGCCATCCGGACCCTGGGCAGACTGCAGGAACTGGGGTTCCATAACAACAACATCAAGGCC ATCCCAGAAAAGGCCTTCATGGGGAACCCTCTGCTACAGACGATACACTTTTATGATAACCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGC CTAAACTCCACACACTATCTCTGAATGGTGCCATGGACATCCAGGAGTTTCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGC AGGCATCCGGCTGCTCCCATCGGGGATGTGCCAACAGCTGCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCAC AGGTGTCAGAAATTGGAGGAAATCGGCCTCCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAAGCCCTGGATC TTAGCTGGAACGCCATCCGGTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGACAACCAGCTGACCACACTGCC CCTGGCTGGACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCCAAGGACAGTTTCCCAAAACTGAGGATCCTG GAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCCTCTGGGCAGTGGGAGGCTGAAGACCTTCACCTTGATGATG AGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAACCACTATGACCAGGACCTGGATGAGCTCCAGCTGGAGATGGAGGACTCAAA GCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCCTTCAAGCCCTGTGAGTACCTCTTTGAAAGCTGGGGCATCCGCCTGGCCGTGTGGGCCATC GTGTTGCTCTCCGTGCTCTGCAATGGACTGGTGCTGCTGACCGTGTTCGCTGGCGGGCCTGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTG CAGGCGCCAACACCTTGACTGGCATTTCCTGTGGCCTTCTAGCCTCAGTCGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGAC GGGGCTAGGCTGCCGGGCCACTGGCTTCCTGGCAGTACTTGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTC TCCTGTGTCCGGGCCTATGGGAAGTCCCCCTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCCGCGCTGCCCC TGGCCTCAGTGGGAGAATACGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGCTTCACCGTGGCCCTGGTGAT GATGAACTCCTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGCGACTTTGAGGCCGTGTGGGACTGCGCCATG GTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTCCTCAGCTTTGCCTCCATGCTGGGCCTCTTCCCTGTCACGC CCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGCCTCAACCCACTGCTGTACCTGCTCTTCAACCCCCACTTCCGGGATGACCT TCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTAGCCTATGCTGCGGCCGGGGAGCTGGAGAAGAGCTCCTGTGATTCTACCCAGGCCCTGGTA GCCTTCTCTGATGTGGATCTCATTCTGGAAGCTTCTGAAGCTGGGCGGCCCCCTGGGCTGGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTC AGCAGCCAGGGGCCCCCAGGCTGGAGGGCAGCCATTGTGTAGAGCCAGAGGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCT GAGGGCAGAGGGATCTACGCCAGCAGGTGGAGGCTTGTCAGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTC CCCATTCTTCTCTTCCCCTCTCTTCCCTTTCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCAGTGTGATCTA TAGCAGGATGGCCCAGTCCCTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCTTTCCCTTGGCCTTCCTCAGC TTCACCTTGATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTGCTTAAGGGAAATGAGGGAAGTAAAGACAGT GAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTGGAAGGTGATTTCCCGTGTGACTCATGGATAGGATACAAAA TGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCCTATTAAAATAAGCTTTGGAAGAGATTACACATGATGTCTTTTTCTTAGAG ATTCACAGTGCATGTTAGTGTAATAAAGAGATAAGTCCTACAGTA

refseq_LGR6.F1 (forward primer)
refseq_LGR6.R1 (reverse primer)
Multiple exon skipping

Frame 0

*KAVVVQRKTHRPRNGKTKVDTCLSSVNNHLCP GPQHEQPHRASAWPLPPPALLGGAASLWEPSLTH PRTSILWSLQPENPDAAEQSAGRNPRRGAVGAA EPAVAAPRCQPHLPGPGEEL*GAVLPPPPLAGR QCTHGDPCQGPQQPPCPAGHDPGPQPHQPHPRLR VPESHQPCGAAFA*QPHPASGDPQLRGAAQSGD TRPEL*QAAGVPCGHPDPGQTAGTGVP*QQHQG HPRKGLHGEPSATDDTLL**PNPVCGKIGIPVPA *TPHTISEWCHGHPGVSRSQRHHQPGDPDPDPR RHPAAPIGDVPTAAQAPSPGTVSQSN*GAAQPA QVSEIGGNRPPTQPHLGNWS*HLQPAELPASPGS *LERHPVHPPRGLLHPALPGQAGPDRQPADHTA PGWTWGLDASEAQREPCSLPGLLQGQFPKTEDP GGALCLPVLSLWDVCQLLQGLWAVGG*RPSP*** GVFKKAPGPPCQTSREPL*PGPG*APAGDGGLK ATPQCPV*PYSRPLQAL*VPL*KLGHPPGRVGH RVALRALQWTGAADRVRWRACPPAPGQVCGRCDC RRQHLDWHFLWPSSLSRCPDLWSVL*VRSPLGD GARLPGHWLPGSTWVGGIGAAAHSGRSAVQRLR LLCPGLWEVPLPGQRSSRGPRLPGTGRAGRRAAP GLSGRIRGLPTLPALRAT*GSASSPGLHRGPGD DELLLFPGRGRCLHQTVL*PAAGRL*GRVGLRH GEARGLAHLRRRAPLLSRGLPQLCLHAGPLPCHA RGRQVCPAGGAAPACLPQPTAVPALQPPLPG*P SAASAPRRGLRAPSLCCGRGAGEELL*FYPGPG SLL*CGSHSGSF*SWAAPWAGDLWLPLSDPHLLS AARGPQAGGQPLCRARGEPLWEPPTLHGWRTAA EGRGIYASRWRLVRGWRLSALWLGLCFTRVNIP PHSSLPLSSLSSLPLGE*WLLLKQIQPKLSSVIY SRMAQSLAPLITSLL*PSPTGASWPGFPLAFLS FTLILGLFLVMSEAVDQRPGLLSA*GK*GK*RQ *RGGGLIRAQWTGRPHRERPGR*FPV*LMDRIQN VFHVPLILTYAMHKDFLLK*ALEEITHDVFFLE IHSAC*CNKEISPTV

Frame 1

ERRLWCKGKPTGQGMGRPRLTLVCQVSIIISAR DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH IPGQAFSGLYSLKILMLQNNQLGGIPAEALWELP SLQSLRLDANLISLVPERSFEGLSSLRHLWLDD NALTEIPVRALNNLPALQAMTLALNRISHIPDY AFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLET LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYL PKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRA GIRLLPSGMCQQLPRLRVLELSHNQIEELPSLH RCQKLEEIGLQHNRIWEIGADTFSQLSSLQALD LSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP LAGLGGLMHLKLKGNLALSQAFSKDSFPKLRIL EVPYAYQCCPYGMCASFFKASGQWEAEDLHLDD EESSKRPLGLLARQAENHYDQDLDELQLEMEDSK PHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAI VLLSVLCNGLVLLTVFAGGPVPLPPVKFVVGAI AGANTLTGISCGLLASVDALTFGQFSEYGARWET GLGCRATGFLAVLGSEASVLLLTLAAVQCSVSV SCVRAYGKSPSLGSVRAGVLGCLALAGLAAALP LASVGEYGASPLCLPYAPPEGQPAALGFTVALVM MNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAM VRHVAWLIFADGLLYCPVAFLSFASMLGLFPVT PEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDL RRLRPRAGDSGPLAYAAAGELEKSSCDSTQALV AFSDVDLILEASEAGRPPGLETYGFPSVTLISC QQPGAPRLEGSHCVEPEGNHFGNPQPSMDGELLL RAEGSTPAGGGLSGGGGFQPSGLAFASHV*ISL PILLFPSLPFPLSPSVNDGCF*NKYNQNSAV*S IAGWPSPWLH*SPLSCDHHQRVPLGLAFPWPSSA SP*YWASSLSCLKLWTRDLDFCLLKGNEGSKDS EGVEG*SGHSGQGDLTEKGLEGDFPCDSWIGYK MCSMYH*S*HMPCIKTSY*NKLWKRLHMMSFS*R FTVHVSVIKR*VLQ

Frame 2

KGGCGAKENPQAKEWEDQG*HLFVKCQ*SSLPG TSA*TTSQSFSLASSTTCASWRSCVSLGTISHT SQDKHSLVSTA*KS*CCRTISWEESPQRRCGSC RACSRCA*MPTSSPWSRRGALRGCPPSATSGWTT MHSRRSLSGPSTTSLPCRP*PWPSTASATSPTT RSRISPALWCCICITTASSIWGPTASRGCTIWR H*T*IITSCRSSLWPSGPWADCRNWGSITTTSRP SQKRPSWGTLCYRRYTFMITQSSLWEDRHSSTC LNSTHYL*MVPWTSRSFQISKAPPAWRS*P*PA QASGCSHRGCANSCPGSESWNCLTIKLRSCPACT GVRNWRKSASNTTASGKLELTPSAS*APCKPWI LAGTPSGPSTPRPSPPCTPWSSWT*QTTS*PHC PWLDLGA*CI*SSKGTLLSPRPSPRTVSQN*GSW RCLMPTSAVPMGCVPASSRPLGSGRLKTFTLMM RSLQKGPWASLPDKQRTTMTRTWMSSSWRWRTQ SHTPVSSVALLQAPSSPVSTSLKAGASAWPCGPS CCSPCSAMDWCC*PCSLAGLSPCPRSSLW*VRL QAPTP*LAFPVAF*PQSMP*PLVSSLSTEPAGR RG*AAGPLASWQYLGRRHRCCCSLWPQCSAASPS PVSGPMGSPPPWAAFEQGS*AAWHWQGWPPRCP WPQWENTGPPHSACPTRHLRVSQQPWASPWPW* **TPSVSWSWPVPTSNCTVTCRGATLRPCGTAPW *GTWPGSSSQTGSSTVPWPSSALPPCWASSLSR PRPSSLSCWWCCPCLPASTHCCTCSSTPTSGMT FGGFGPAQGTQGP*PMLRPGSWRRAPVILPRPW* PSLMWISFWKLLKLGGPLGWRPMASPQ*PSSPV SSQGPPGWRAAIV*SQRGTTLGTPNPPWMENCC *GQRDLRQQVEACQGVAAFSPLAWPLLHTCKYPS PFFSSPLFPFLSPPR*MMAASKTNTTKTQQCDL *QDGPVPGSTDHLSPVTITNGCLLAWLSLGLPQ LHLDTGPLPCHV*SCGPETWTFVCLREMREVKTV KGWRVDQGTVDRETSQRKAWKVISRVTHG*DTK CVPCTINLDICHA*RLPIKISFGRDYT*CLFLR DSQCMLV**RDKSYS

Sequence NM_001017403

ATGCCCAGCCCGCCGGGGCTCCGGGCGCTATGGCTTTGCGCCGCGCTGTGCGCTTCCCGGAGGGCCGGCGGCGCCCCCCAGCCCGGCCCGGGGCCCACCG CCTGCCCGGCCCCCTGCCACTGCCAGGAGGACGGCATCATGCTGTCTGCCGACTGCTCTGAGCTCGGGCTGTCCGCCGTTCCGGGGGACCTGGACCCCCT GACGGCTTACCTGGACCTCAGCATGAACAACCTCACAGAGCTTCAGCCTGGCCTCTTCCACCACCTGCGCTTCTTGGAGGAGCTGCGTCTCTCTGGGAAC CATCTCTCACACATCCCAGGACAAGCATTCTCTGGTCTCTACAGCCTGAAAATCCTGATGCTGCAGAACAATCAGCTGGGAGGAATCCCCGCAGAGGCGC TGTGGGAGCTGCCGAGCCTGCAGTCGCTGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTGTCCTCCCTCCGCCACCT CTGGCTGGACGACAATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATGACCCTGGCCCTCAACCGCATCAGCCAC ATCCCCGACTACGCGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGCATCCAGCATCTGGGGACCCACAGCTTCGAGGGGCTGC ACAATCTGGAGACACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTGGCCATCCGGACCCTGGGCAGACTGCAGGAACTGGGGTTCCATAACAA CAACATCAAGGCCATCCCAGAAAAGGCCTTCATGGGGAACCCTCTGCTACAGACGATACACTTTTATGATAACCCAATCCAGTTTGTGGGAAGATCGGCA TTCCAGTACCTGCCTAAACTCCACACACTATCTCTGAATGGTGCCATGGACATCCAGGAGTTTCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGA CCCTGACCCGCGCAGGCATCCGGCTGCTCCCATCGGGGATGTGCCAACAGCTGCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCT GCCCAGCCTGCACAGGTGTCAGAAATTGGAGGAAATCGGCCTCCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTG CAAGCCCTGGATCTTAGCTGGAACGCCATCCGGTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGACAACCAGC TGACCACACTGCCCCTGGCTGGACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCCAAGGACAGTTTCCCAAA ACTGAGGATCCTGGAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCCTCTGGGCAGTGGGAGGCTGAAGACCTT CACCTTGATGATGAGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAACCACTATGACCAGGACCTGGATGAGCTCCAGCTGGAGA TGGAGGACTCAAAGCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCCTTCAAGCCCTGTGAGTACCTCTTTGAAAGCTGGGGCATCCGCCTGGC CGTGTGGGCCATCGTGTTGCTCTCCGTGCTCTGCAATGGACTGGTGCTGCTGACCGTGTTCGCTGGCGGGCCTGTCCCCCTGCCCCCGGTCAAGTTTGTG GTAGGTGCGATTGCAGGCGCCAACACCTTGACTGGCATTTCCTGTGGCCTTCTAGCCTCAGTCGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAG CCCGCTGGGAGACGGGGCTAGGCTGCCGGGCCACTGGCTTCCTGGCAGTACTTGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTG CAGCGTCTCCGTCTCCTGTGTCCGGGCCTATGGGAAGTCCCCCTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCC GCCGCGCTGCCCCTGGCCTCAGTGGGAGAATACGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGCTTCACCG TGGCCCTGGTGATGATGAACTCCTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGCGACTTTGAGGCCGTGTG GGACTGCGCCATGGTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTCCTCAGCTTTGCCTCCATGCTGGGCCTC TTCCCTGTCACGCCCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGCCTCAACCCACTGCTGTACCTGCTCTTCAACCCCCACT TCCGGGATGACCTTCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTAGCCTATGCTGCGGCCGGGGAGCTGGAGAAGAGCTCCTGTGATTCTAC CCAGGCCCTGGTAGCCTTCTCTGATGTGGATCTCATTCTGGAAGCTTCTGAAGCTGGGCGGCCCCCTGGGCTGGAGACCTATGGCTTCCCCTCAGTGACC CTCATCTCCTGTCAGCAGCCAGGGGCCCCCAGGCTGGAGGGCAGCCATTGTGTAGAGCCAGAGGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATG GAGAACTGCTGCTGAGGGCAGAGGGATCTACGCCAGCAGGTGGAGGCTTGTCAGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGT GTAAATATCCCTCCCCATTCTTCTCTTCCCCTCTCTTCCCTTTCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCA GCAGTGTGATCTATAGCAGGATGGCCCAGTCCCTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCTTTCCCTT GGCCTTCCTCAGCTTCACCTTGATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTGCTTAAGGGAAATGAGGG AAGTAAAGACAGTGAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTGGAAGGTGATTTCCCGTGTGACTCATGG ATAGGATACAAAATGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCCTATTAAAATAAGCTTTGGAAGAGATTACACATGATGT CTTTTTCTTAGAGATTCACAGTGCATGTTAGTGTAATAAAGAGATAAGTCCTACAGTA

refseq_LGR6.F1 (forward primer)
refseq_LGR6.R1 (reverse primer)
Multiple exon skipping

Frame 0

MPSPPGLRALWLCAALCASRRAGGAPQPGPGPT ACPAPCHCQEDGIMLSADCSELGLSAVPGDLDPL TAYLDLSMNNLTELQPGLFHHLRFLEELRLSGN HLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEA LWELPSLQSLRLDANLISLVPERSFEGLSSLRHL WLDDNALTEIPVRALNNLPALQAMTLALNRISH IPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL HNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNN NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSA FQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEIL TLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSL QALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQ LTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPK LRILEVPYAYQCCPYGMCASFFKASGQWEAEDL HLDDEESSKRPLGLLARQAENHYDQDLDELQLE MEDSKPHPSVQCSPTPGPFKPCEYLFESWGIRLA VWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFV VGAIAGANTLTGISCGLLASVDALTFGQFSEYG ARWETGLGCRATGFLAVLGSEASVLLLTLAAVQC SVSVSCVRAYGKSPSLGSVRAGVLGCLALAGLA AALPLASVGEYGASPLCLPYAPPEGQPAALGFT VALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVW DCAMVRHVAWLIFADGLLYCPVAFLSFASMLGL FPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPH FRDDLRRLRPRAGDSGPLAYAAAGELEKSSCDST QALVAFSDVDLILEASEAGRPPGLETYGFPSVT LISCQQPGAPRLEGSHCVEPEGNHFGNPQPSMD GELLLRAEGSTPAGGGLSGGGGFQPSGLAFASHV *ISLPILLFPSLPFPLSPSVNDGCF*NKYNQNS AV*SIAGWPSPWLH*SPLSCDHHQRVPLGLAFP WPSSASP*YWASSLSCLKLWTRDLDFCLLKGNEG SKDSEGVEG*SGHSGQGDLTEKGLEGDFPCDSW IGYKMCSMYH*S*HMPCIKTSY*NKLWKRLHMM SFS*RFTVHVSVIKR*VLQ

Frame 1

CPARRGSGRYGFAPRCALPGGPAAPPSPARGPP PARPPATARRTASCCLPTALSSGCPPFRGTWTP *RLTWTSA*TTSQSFSLASSTTCASWRSCVSLGT ISHTSQDKHSLVSTA*KS*CCRTISWEESPQRR CGSCRACSRCA*MPTSSPWSRRGALRGCPPSAT SGWTTMHSRRSLSGPSTTSLPCRP*PWPSTASAT SPTTRSRISPALWCCICITTASSIWGPTASRGC TIWRH*T*IITSCRSSLWPSGPWADCRNWGSIT TTSRPSQKRPSWGTLCYRRYTFMITQSSLWEDRH SSTCLNSTHYL*MVPWTSRSFQISKAPPAWRS* P*PAQASGCSHRGCANSCPGSESWNCLTIKLRS CPACTGVRNWRKSASNTTASGKLELTPSAS*APC KPWILAGTPSGPSTPRPSPPCTPWSSWT*QTTS *PHCPWLDLGA*CI*SSKGTLLSPRPSPRTVSQ N*GSWRCLMPTSAVPMGCVPASSRPLGSGRLKTF TLMMRSLQKGPWASLPDKQRTTMTRTWMSSSWR WRTQSHTPVSSVALLQAPSSPVSTSLKAGASAW PCGPSCCSPCSAMDWCC*PCSLAGLSPCPRSSLW *VRLQAPTP*LAFPVAF*PQSMP*PLVSSLSTE PAGRRG*AAGPLASWQYLGRRHRCCCSLWPQCS AASPSPVSGPMGSPPPWAAFEQGS*AAWHWQGWP PRCPWPQWENTGPPHSACPTRHLRVSQQPWASP WPW***TPSVSWSWPVPTSNCTVTCRGATLRPC GTAPW*GTWPGSSSQTGSSTVPWPSSALPPCWAS SLSRPRPSSLSCWWCCPCLPASTHCCTCSSTPT SGMTFGGFGPAQGTQGP*PMLRPGSWRRAPVIL PRPW*PSLMWISFWKLLKLGGPLGWRPMASPQ*P SSPVSSQGPPGWRAAIV*SQRGTTLGTPNPPWM ENCC*GQRDLRQQVEACQGVAAFSPLAWPLLHT CKYPSPFFSSPLFPFLSPPR*MMAASKTNTTKTQ QCDL*QDGPVPGSTDHLSPVTITNGCLLAWLSL GLPQLHLDTGPLPCHV*SCGPETWTFVCLREMR EVKTVKGWRVDQGTVDRETSQRKAWKVISRVTHG *DTKCVPCTINLDICHA*RLPIKISFGRDYT*C LFLRDSQCMLV**RDKSYS

Frame 2

AQPAGAPGAMALRRAVRFPEGRRRPPARPGAHR LPGPLPLPGGRHHAVCRLL*ARAVRRSGGPGPP DGLPGPQHEQPHRASAWPLPPPALLGGAASLWE PSLTHPRTSILWSLQPENPDAAEQSAGRNPRRGA VGAAEPAVAAPRCQPHLPGPGEEL*GAVLPPPP LAGRQCTHGDPCQGPQQPPCPAGHDPGPQPHQP HPRLRVPESHQPCGAAFA*QPHPASGDPQLRGAA QSGDTRPEL*QAAGVPCGHPDPGQTAGTGVP*Q QHQGHPRKGLHGEPSATDDTLL**PNPVCGKIG IPVPA*TPHTISEWCHGHPGVSRSQRHHQPGDPD PDPRRHPAAPIGDVPTAAQAPSPGTVSQSN*GA AQPAQVSEIGGNRPPTQPHLGNWS*HLQPAELP ASPGS*LERHPVHPPRGLLHPALPGQAGPDRQPA DHTAPGWTWGLDASEAQREPCSLPGLLQGQFPK TEDPGGALCLPVLSLWDVCQLLQGLWAVGG*RP SP***GVFKKAPGPPCQTSREPL*PGPG*APAGD GGLKATPQCPV*PYSRPLQAL*VPL*KLGHPPG RVGHRVALRALQWTGAADRVRWRACPPAPGQVC GRCDCRRQHLDWHFLWPSSLSRCPDLWSVL*VRS PLGDGARLPGHWLPGSTWVGGIGAAAHSGRSAV QRLRLLCPGLWEVPLPGQRSSRGPRLPGTGRAG RRAAPGLSGRIRGLPTLPALRAT*GSASSPGLHR GPGDDELLLFPGRGRCLHQTVL*PAAGRL*GRV GLRHGEARGLAHLRRRAPLLSRGLPQLCLHAGP LPCHARGRQVCPAGGAAPACLPQPTAVPALQPPL PG*PSAASAPRRGLRAPSLCCGRGAGEELL*FY PGPGSLL*CGSHSGSF*SWAAPWAGDLWLPLSD PHLLSAARGPQAGGQPLCRARGEPLWEPPTLHGW RTAAEGRGIYASRWRLVRGWRLSALWLGLCFTR VNIPPHSSLPLSSLSSLPLGE*WLLLKQIQPKL SSVIYSRMAQSLAPLITSLL*PSPTGASWPGFPL AFLSFTLILGLFLVMSEAVDQRPGLLSA*GK*G K*RQ*RGGGLIRAQWTGRPHRERPGR*FPV*LM DRIQNVFHVPLILTYAMHKDFLLK*ALEEITHDV FFLEIHSAC*CNKEISPTV