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Sequences

Sequence NM_213569

CCTGCGCGGCGGCGGCGGCGAGGCGGGGGAGCGAGTGAGCGCGAGGGGCGGGCGCGAGTGACTGTGTGAGTCACCCGTACCTGGAGTGCGAGCGACGCAG
AGCCAGCGGCGCGGAGCCGGAGCCGGAGCCGAGACCCAGCGCCTGCGAGCCCGAGAGCGCGGCCGGCCCCAGGCGCCAGGCCCCGTCGCCCTCCCCGTGC
ACTCACCCGTGGCCCGGCGCCGACTCCCTACCCGGCGCCCGCCGCCCGCAGCCCTCCCGCCTGCCAGGAGGCGGTGCGGGGCTCGCCGGGGGATGTCACA
GCGGCTCCTGGGAGCCAGCAGCCGCCGCCGCCGCCGCCCCCGGGAACCGCGATCATGAACCCCCAGTGCGCCCGTTGCGGAAAAGTCGTGTATCCCACCG
AGAAAGTCAACTGCCTGGATAAGTATTGGCATAAAGGATGTTTCCATTGTGAGGTCTGCAAGATGGCACTCAACATGAACAACTACAAAGGCTATGAAAA
GAAGCCCTATTGTAATGCACACTACCCGAAGCAGTCCTTCACCACGGTGGCAGATACACCTGAAAATCTTCGCCTGAAGCAGCAAAGTGAATTGCAGAGT
CAGGTCAAGTACAAAAGAGATTTTGAAGAAAGCAAAGGGAGGGGCTTCAGCATCGTCACGGACACTCCTGAGCTACAGAGACTGAAGAGGACTCAGGAGC
AAATCAGTAATGTAAAATACCATGAAGATTTTGAAAAAACAAAGGGGAGAGGCTTTACTCCCGTCGTGGACGATCCTGTGACAGAGAGAGTGAGGAAGAA
CACCCAGGTGGTCAGCGATGCTGCCTATAAAGGGGTCCACCCTCACATCGTGGAGATGGACAGGAGACCTGGAATCATTGTTGCACCTGTTCTTCCCGGA
GCCTATCAGCAAAGCCATTCCCAAGGCTATGGCTACATGCACCAGACCAGTGTGTCATCCATGAGATCAATGCAGCATTCACCAAATCTAAGGACCTACC
GAGCCATGTACGATTACAGTGCCCAGGATGAAGACGAGGTCTCCTTTAGAGACGGCGACTACATCGTCAACGTGCAGCCTATTGACGATGGCTGGATGTA
CGGCACAGTGCAGAGAACAGGGAGAACAGGAATGCTCCCAGCGAATTACATTGAGTTTGTTAATTAATTATTTCTCCCTGCCCTTTGAGCTTTATTCTAA
TGTATCCCAAACCTAATCTTTTTAAAAGATAGAAGATACTTTTAAGACAACTTGGCCATTATTTTACAATGATGTATCCTTCCTTTGACAATTAGACACA
CAGGTACCAGGAAGAAGGAATGACCTCTGGGCTGAAAACAGCAGCATTTTCAGTAATTCCTACAAACAAAAATCTTTGTGTCTGGACACCTGGTGCTGCT
AATTGTGTTCATGGTTTCCTTTGATTGGCTATTGAACCCTTCTGGGAAATGTATTTTTGTAGACTTTAATAGAGAAGTTGATTGTCCCTTAAATGTAGTG
TGTGTTTGAAACTTCTTAGCTGTCACTTTGGAATCACCCCAAGCCAATTCTCTTAACTCTGTAATGCAGCCAATAATTTCAAACCCGTTTTGCTTTTGAG
TCATGAGGCAATTTCCAATATTAGTGAAAATTGCCCAATATAATAAGTGTAAACAGTGGCAGAAGGACAGTCTGGTTAAAATTATATTGACTGGTGGCCT
TAGGGATCTAGAAACTTCTACTAAACAGAGAAATTTCCTTGTTCCCTAGGCTGACTGGTATCTATTTATTTCTCATTTGTACCAAGGCATCTCCTACTCT
CCATTTATATTCTATGGACCCAAGTCTATGCTCAGTTCCACAGAATGTCAGGACCAAATAACTTCACAGCTACTCTGCAAAGGGCAAATTATAATGTCAT
TGATATAATTTCCCTAGTAGCATTTACCCTGTTGCATGTCATGTAGATTCAAGCTTCTGTAACATAGGCAGCTGCACTGCGCGTTCCTATTATTGAAGCA
AAAAGGGTGACTGATACCTAAAAGCCCTTTCTTCCTCTAGTCGCCAGCTCATCAGAAAAACATACTTTGAAAAGATGCTTGAGATTTTCCTGCTGCATCG
CACTCTAGTTTTGAAGGATTTACATCTTAGGAAATAACATGTATACTCTAGTAAATAAGCGATTTAGGTGTTCCATTGAACAGCTTTGATTAACTTAATG
CCACCATTGATTTCAAAGTGAAGAAAATGTAACAGAAGCCAGTGAAGCAATGGAAGCTGGAGTGTGACTGGAAAAATACTCAGCAAACAAAGTTACCAAT
TCCATACAGAGATGATCTGGTATCTTCTTTTGGAAAATGGTATTCAAATTCTGGAATGGAAATCTAGCCACCAAAACGGGTTAATCAAAAGACGTCCTTT
TCCATTTTTTTTTGCTTTTATTTTCTAAATCATTTTTAAGGGAATGAAACAGGAATGTCATCAGAGATTTTTTAGTACAGGCCCAAGAGCCTGTTCTCTA
AGAAAGAAATTGTTGCCATGTTTTGATTTTCGAATAAGTGACTTTGCAGGCTTTATGCTAGCCCTTGCTGGTGGGTCTTGAAATTTCATCCAGAGTCTGC
AGTCCAGGTCACCAAGCCAGCGGCACCCGTCGGCAACCCTGTGTTTTTCTGATTGTGCCGTTTACTGTGACCTGCAACGGGGTGGCATTCACTTAGGGTC
TGACTTCACAGCTATGACAAAACCGAAAAAGCAAAACTGCAAAAAAGTACTAAGATGTACGGGTCTTGGGGATATCTGCCTTATATGTTATATTCAAGGA
AATTAACAAAACATCCTGTAAAACATCGTTTAAGGAAACGTTTACTAGTCCAAAGGCCAAAGCTAATTTATTTCCACTTTAGAAAAGTTAGCACATGCTT
TTGAAAATCTGTGATTTCATTTTATTAGGCTAAAAGGGTAAATAGGCTTTATTACACTGAAGCTGCATCTATATGTCACTGACATAAAGTTGAAAAAATA
AATGCAGGCAAATAACTAGAGACTTCTTTTAAGGGGGTTTGGCTGGTTTTCTCTCACTGAAATGGCCAGTCGTGATTAAAGTGATAAAACCCCATATCTG
TTTTGGTATATTGTACACAAACCTACAAAAATAAACTGAACTTGCAATATTTTTGCAAAAAAATCTGTCGTTAAAACTGAGGATAAAATACCTGCTCAAT
TTTATTTTACTAAGTATATATTTACATTTCACCCAGGCAGGCCATTTTCTTTTGTGATTATAAGAAAGAGTAGTTGTTGATTAAATTTTCAGACTAAATA
TAGGACAGGTACAATTTTGGATAAATAGCACATTTATAAGAACCGCAATGAAAACTGACTTGAAATAATGCTTGTAATCAGGAAAGTAATTTCATCCACC
GATTTCAAAACCAGATTCACTGAGCATAAAAGTCAATACATATTTGAGGAATAAGTCTCCTAAAATTTTAAGCTTCACGTAATAATGTTTGCATAGCAAA
ATATTTCTGCTTCAAGCCTTTAGGAATTAAGATCTGATCAGAATTTAACTAAAGGGTAGTTGTTTTACAATGAAGACTAAAACTGAACAAGATGTTGCAT
GCTCTTGAGGCCATAATTTGGTAGTGTTGGCAGTTGTTAATAAAGCTTGTCAGGATGTTAAGCATCTCAGGAGAAATATTGGAAAATTATATGTATAAAA
CCAAAGTGCTATTTTTAAAAGCATCATTTAAAAAAAAATGACATGCCTGAACAACTTTTCCACTTTCCACGTGCTTCCCTCCCACCTTTGGTTTGGCAAC
AGGTATCTCGTGCATGAAGCTGACAGCTAAAGAAGATTTTAAAAATTGAGTTAAAGATGACTGTGTAAATGTCCAAGCACAGAGAGCATGCACCTGACTT
TCTAAAGTTTGATGTGTTCTCAAGCCTGACAGAAGCACAAGGAACAGTTTGATACACTTTTAAAAGGTTCTGAAAACAAAGCTGTATAGGGATCCTCTCT
CTCTTGAGCAAAGTATAGCAACAGAATATATTGCTTTTGTTGTAAGCTTTTGTAGTACATGTTTTTACTAATAATTCTTGTTCTCTAGAAAGCTTTCTAT
TTCTAACCTATGGCAAAATGAATCCTTCATGTCTTCTTGTTATTGTTTACACACTTGCAGTGTAGCCCAGTTTGAAATATTTATTTGGTTATCAACTGCC
CATGGAGGAGGCTCTTGATGATCCCAGGTCTCCTCGACCTCCATACACCACACAGGCATTTGTAAGCACAGTTTCCACAAGCACCTTGTAGGAATATGGA
TAAGATTAGACCAGCCCCTCTCTGTCCACTGGGTTTATTTCTTGAAGAAGATGCAGATCTGGTTTTTCCAATGTGCCACAGTCTTTCCTTATCCTCTCCA
TGCTGAGCTTGACAACACTCTGGGAATGAGGAACAAGACTTTTTCTAAAAAGATAGTGGAAGTTCAAGGGATGTACCTCGTTTTCAGGTTCATCCATCTC
CAGTGGAATGTTTTCAATAAAAGATGAAGAAAATGTGTGTGATCTTTAATAACACATCCCTATAGAAAGTGGATAAAAGATATACCAAAACTGTAATACA
GATATATACAAATATAGGTGCCTTTTTGATTACTCTTGTTTGTCTAGTATGCTCTTGGAAAGAAAACCAAGCAAGCAAGTTGCTGCCTATTCTATAGTAA
TATTTTATTACACATGATTGATATTTTTGTGGTAGGGAAGTGGGATGCTCCTCAGATATTAAAGGTGTTAGCTGATTGTATTTTATCTCTAAAGATTTAG
AACTTTAGAAAATGCCGACTTCTTCCATCTATTTCTGAAAGGTTCTTTGTGGATTTATATAGAGTTGAGCTATATAAACATTAACTTTAGATTTGGGATT
TAAAATGCCTATTGTAAGATAGAATAATTGTGAGGCTGGATTCACTACACAAGATGAACTTCACTTCATAAATTAATTATACCTTAGCGATTTGCTTCTG
ATAATCTAAAAGTGGCTAGATTGTGGTTGTTTTGGTTAAGGTGATATGGAGGTGGGAGAGCTTTTAGTTAAGTAAGAAGCTATGTAAACTGACAAGGATG
CTAAAATAAAAGTCTCTGAAGTATTCCATGCCTTTTGGACCCTTTCCTCGCAACTAACTGTCAACTGTTGATCAAAAAAGTCAAGGCATTGTATGTTGCT
TCTGTGGTTATTATTCTGTGATGCTTAGACTACTTGAACCCATAAACTTGGAAGAATCTTTGAGCAAATTTTCTCAGTTGTCTGTATGACTTCAGTATAT
TCCTGGGAATGCCATAGGATTTTTTGTGCTTGATACATGGTATCCAGTTTGCATAGTATCACTTCTTTGTAATCCAGTTGCTGTTAAGAATGATGTACTT
TAAAGGAAAAGAGAAAACTGCATCACAGTCCCATTCTCCAGTGTCCATGCAATGAATTGCTGAGCATTTAGGAAGCAGCACCAAGTCTATTACAGGCATG
GTGTGAAACTTGATGTTTGACCTGTGATCAAAATTGAACCATTGTACAGTTTGGCTTCTGTTTGCTTCAAAATATGTAGAATTGTGGTTGATGATTAATT
TGCGAGACTAACTTTGAGAGTGTAACAGTTTTGAAGAAAACATTGAATGTTTTGCAAATGAAGGGGCTTCACGGAATGTTACAATGTTACTAATATAATT
TGGCTTTTGTTATGCAAATTGTTAACACCAGCTATTAAAATATATTTTAGTAGAAA
  • refseq_NEBL.F1 (forward primer)
  • refseq_NEBL.R1 (reverse primer)
  • Multiple exon skipping

Frame 0

PARRRRRGGGASEREGRARVTV*VTRTWSASDA
EPAARSRSRSRDPAPASPRARPAPGARPRRPPRA
LTRGPAPTPYPAPAARSPPACQEAVRGSPGDVT
AAPGSQQPPPPPPPGTAIMNPQCARCGKVVYPT
EKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEK
KPYCNAHYPKQSFTTVADTPENLRLKQQSELQS
QVKYKRDFEESKGRGFSIVTDTPELQRLKRTQE
QISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKN
TQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPG
AYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTY
RAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMY
GTVQRTGRTGMLPANYIEFVN*LFLPAL*ALF*
CIPNLIFLKDRRYF*DNLAIILQ*CILPLTIRH
TGTRKKE*PLG*KQQHFQ*FLQTKIFVSGHLVLL
IVFMVSFDWLLNPSGKCIFVDFNREVDCPLNVV
CV*NFLAVTLESPQANSLNSVMQPIISNPFCF*
VMRQFPILVKIAQYNKCKQWQKDSLVKIILTGGL
RDLETSTKQRNFLVP*ADWYLFISHLYQGISYS
PFIFYGPKSMLSSTECQDQITSQLLCKGQIIMS
LI*FP**HLPCCMSCRFKLL*HRQLHCAFLLLKQ
KG*LIPKSPFFL*SPAHQKNIL*KDA*DFPAAS
HSSFEGFTS*EITCIL**ISDLGVPLNSFD*LN
ATIDFKVKKM*QKPVKQWKLECDWKNTQQTKLPI
PYRDDLVSSFGKWYSNSGMEI*PPKRVNQKTSF
SIFFCFYFLNHF*GNETGMSSEIF*YRPKSLFS
KKEIVAMF*FSNK*LCRLYASPCWWVLKFHPESA
VQVTKPAAPVGNPVFF*LCRLL*PATGWHSLRV
*LHSYDKTEKAKLQKSTKMYGSWGYLPYMLYSR
KLTKHPVKHRLRKRLLVQRPKLIYFHFRKVSTCF
*KSVISFY*AKRVNRLYYTEAASICH*HKVEKI
NAGK*LETSFKGVWLVFSH*NGQS*LK**NPIS
VLVYCTQTYKNKLNLQYFCKKICR*N*G*NTCSI
LFY*VYIYISPRQAIFFCDYKKE*LLIKFSD*I
*DRYNFG*IAHL*EPQ*KLT*NNACNQESNFIH
RFQNQIH*A*KSIHI*GISLLKF*ASRNNVCIAK
YFCFKPLGIKI*SEFN*RVVVLQ*RLKLNKMLH
ALEAIIW*CWQLLIKLVRMLSISGEILENYMYK
TKVLFLKASFKKK*HA*TTFPLSTCFPPTFGLAT
GISCMKLTAKEDFKN*VKDDCVNVQAQRACT*L
SKV*CVLKPDRSTRNSLIHF*KVLKTKLYRDPL
SLEQSIATEYIAFVVSFCSTCFY**FLFSRKLSI
SNLWQNESFMSSCYCLHTCSVAQFEIFIWLSTA
HGGGS**SQVSSTSIHHTGICKHSFHKHLVGIW
IRLDQPLSVHWVYFLKKMQIWFFQCATVFPYPLH
AELDNTLGMRNKTFSKKIVEVQGMYLVFRFIHL
QWNVFNKR*RKCV*SLITHPYRKWIKDIPKL*Y
RYIQI*VPF*LLLFV*YALGKKTKQASCCLFYSN
ILLHMIDIFVVGKWDAPQILKVLADCILSLKI*
NFRKCRLLPSISERFFVDLYRVELYKH*L*IWD
LKCLL*DRIIVRLDSLHKMNFTS*INYTLAICF*
*SKSG*IVVVLVKVIWRWESF*LSKKLCKLTRM
LK*KSLKYSMPFGPFPRN*LSTVDQKSQGIVCC
FCGYYSVMLRLLEPINLEESLSKFSQLSV*LQYI
PGNAIGFFVLDTWYPVCIVSLLCNPVAVKNDVL
*RKRENCITVPFSSVHAMNC*AFRKQHQVYYRH
GVKLDV*PVIKIEPLYSLASVCFKICRIVVDD*F
ARLTLRV*QF*RKH*MFCK*RGFTECYNVTNII
WLLLCKLLTPAIKIYFSR

Frame 1

LRGGGGEAGERVSARGGRE*LCESPVPGVRATQ
SQRRGAGAGAETQRLRARERGRPQAPGPVALPV
HSPVARRRLPTRRPPPAALPPARRRCGARRGMSQ
RLLGASSRRRRRPREPRS*TPSAPVAEKSCIPP
RKSTAWISIGIKDVSIVRSARWHST*TTTKAMK
RSPIVMHTTRSSPSPRWQIHLKIFA*SSKVNCRV
RSSTKEILKKAKGGASASSRTLLSYRD*RGLRS
KSVM*NTMKILKKQRGEALLPSWTIL*QRE*GR
TPRWSAMLPIKGSTLTSWRWTGDLESLLHLFFPE
PISKAIPKAMATCTRPVCHP*DQCSIHQI*GPT
EPCTITVPRMKTRSPLETATTSSTCSLLTMAGC
TAQCREQGEQECSQRITLSLLINYFSLPFELYSN
VSQT*SF*KIEDTFKTTWPLFYNDVSFL*QLDT
QVPGRRNDLWAENSSIFSNSYKQKSLCLDTWCC
*LCSWFPLIGY*TLLGNVFL*TLIEKLIVP*M*C
VFETS*LSLWNHPKPILLTL*CSQ*FQTRFAFE
S*GNFQY**KLPNIISVNSGRRTVWLKLY*LVA
LGI*KLLLNREISLFPRLTGIYLFLICTKASPTL
HLYSMDPSLCSVPQNVRTK*LHSYSAKGKL*CH
*YNFPSSIYPVACHVDSSFCNIGSCTARSYY*S
KKGD*YLKALSSSSRQLIRKTYFEKMLEIFLLHR
TLVLKDLHLRK*HVYSSK*AI*VFH*TALINLM
PPLISK*RKCNRSQ*SNGSWSVTGKILSKQSYQ
FHTEMIWYLLLENGIQILEWKSSHQNGLIKRRPF
PFFFAFIF*IIFKGMKQECHQRFFSTGPRACSL
RKKLLPCFDFRISDFAGFMLALAGGS*NFIQSL
QSRSPSQRHPSATLCFSDCAVYCDLQRGGIHLGS
DFTAMTKPKKQNCKKVLRCTGLGDICLICYIQG
N*QNIL*NIV*GNVY*SKGQS*FISTLEKLAHA
FENL*FHFIRLKG*IGFITLKLHLYVTDIKLKK*
MQANN*RLLLRGFGWFSLTEMASRD*SDKTPYL
FWYIVHKPTKIN*TCNIFAKKSVVKTEDKIPAQ
FYFTKYIFTFHPGRPFSFVIIRKSSC*LNFQTKY
RTGTILDK*HIYKNRNEN*LEIMLVIRKVISST
DFKTRFTEHKSQYIFEE*VS*NFKLHVIMFA*Q
NISASSL*ELRSDQNLTKG*LFYNED*N*TRCCM
LLRP*FGSVGSC**SLSGC*ASQEKYWKIICIK
PKCYF*KHHLKKNDMPEQLFHFPRASLPPLVWQ
QVSRA*S*QLKKILKIELKMTV*MSKHREHAPDF
LKFDVFSSLTEAQGTV*YTFKRF*KQSCIGILS
LLSKV*QQNILLLL*AFVVHVFTNNSCSLESFL
FLTYGKMNPSCLLVIVYTLAV*PSLKYLFGYQLP
MEEALDDPRSPRPPYTTQAFVSTVSTSTL*EYG
*D*TSPSLSTGFIS*RRCRSGFSNVPQSFLILS
MLSLTTLWE*GTRLFLKR*WKFKGCTSFSGSSIS
SGMFSIKDEENVCDL**HIPIESG*KIYQNCNT
DIYKYRCLFDYSCLSSMLLERKPSKQVAAYSIV
IFYYT*LIFLW*GSGMLLRY*RC*LIVFYL*RFR
TLENADFFHLFLKGSLWIYIELSYININFRFGI
*NAYCKIE*L*GWIHYTR*TSLHKLIIP*RFAS
DNLKVARLWLFWLR*YGGGRAFS*VRSYVN*QGC
*NKSL*SIPCLLDPFLATNCQLLIKKVKALYVA
SVVIIL*CLDYLNP*TWKNL*ANFLSCLYDFSI
FLGMP*DFLCLIHGIQFA*YHFFVIQLLLRMMYF
KGKEKTASQSHSPVSMQ*IAEHLGSSTKSITGM
V*NLMFDL*SKLNHCTVWLLFASKYVELWLMIN
LRD*L*ECNSFEENIECFANEGASRNVTMLLI*F
GFCYANC*HQLLKYILVE

Frame 2

CAAAAARRGSE*ARGAGASDCVSHPYLECERRR
ASGAEPEPEPRPSACEPESAAGPRRQAPSPSPC
THPWPGADSLPGARRPQPSRLPGGGAGLAGGCH
SGSWEPAAAAAAAPGNRDHEPPVRPLRKSRVSHR
ESQLPG*VLA*RMFPL*GLQDGTQHEQLQRL*K
EALL*CTLPEAVLHHGGRYT*KSSPEAAK*IAE
SGQVQKRF*RKQREGLQHRHGHS*ATETEEDSGA
NQ*CKIP*RF*KNKGERLYSRRGRSCDRESEEE
HPGGQRCCL*RGPPSHRGDGQETWNHCCTCSSR
SLSAKPFPRLWLHAPDQCVIHEINAAFTKSKDLP
SHVRLQCPG*RRGLL*RRRLHRQRAAY*RWLDV
RHSAENRENRNAPSELH*VC*LIISPCPLSFIL
MYPKPNLFKR*KILLRQLGHYFTMMYPSFDN*TH
RYQEEGMTSGLKTAAFSVIPTNKNLCVWTPGAA
NCVHGFL*LAIEPFWEMYFCRL**RS*LSLKCS
VCLKLLSCHFGITPSQFS*LCNAANNFKPVLLLS
HEAISNISENCPI**V*TVAEGQSG*NYIDWWP
*GSRNFY*TEKFPCSLG*LVSIYFSFVPRHLLL
SIYILWTQVYAQFHRMSGPNNFTATLQRANYNVI
DIISLVAFTLLHVM*IQASVT*AAALRVPIIEA
KRVTDT*KPFLPLVASSSEKHTLKRCLRFSCCI
AL*F*RIYILGNNMYTLVNKRFRCSIEQL*LT*C
HH*FQSEENVTEASEAMEAGV*LEKYSANKVTN
SIQR*SGIFFWKMVFKFWNGNLATKTG*SKDVL
FHFFLLLFSKSFLRE*NRNVIRDFLVQAQEPVL*
ERNCCHVLIFE*VTLQALC*PLLVGLEISSRVC
SPGHQASGTRRQPCVFLIVPFTVTCNGVAFT*G
LTSQL*QNRKSKTAKKY*DVRVLGISALYVIFKE
INKTSCKTSFKETFTSPKAKANLFPL*KS*HML
LKICDFILLG*KGK*ALLH*SCIYMSLT*S*KN
KCRQITRDFF*GGLAGFLSLKWPVVIKVIKPHIC
FGILYTNLQK*TELAIFLQKNLSLKLRIKYLLN
FILLSIYLHFTQAGHFLL*L*ERVVVD*IFRLN
IGQVQFWINSTFIRTAMKTDLK*CL*SGK*FHPP
ISKPDSLSIKVNTYLRNKSPKILSFT**CLHSK
IFLLQAFRN*DLIRI*LKGSCFTMKTKTEQDVA
CS*GHNLVVLAVVNKACQDVKHLRRNIGKLYV*N
QSAIFKSII*KKMTCLNNFSTFHVLPSHLWFGN
RYLVHEADS*RRF*KLS*R*LCKCPSTESMHLT
F*SLMCSQA*QKHKEQFDTLLKGSENKAV*GSSL
S*AKYSNRIYCFCCKLL*YMFLLIILVL*KAFY
F*PMAK*ILHVFLLLFTHLQCSPV*NIYLVINC
PWRRLLMIPGLLDLHTPHRHL*AQFPQAPCRNMD
KIRPAPLCPLGLFLEEDADLVFPMCHSLSLSSP
C*A*QHSGNEEQDFF*KDSGSSRDVPRFQVHPS
PVECFQ*KMKKMCVIFNNTSL*KVDKRYTKTVIQ
IYTNIGAFLITLVCLVCSWKENQASKLLPIL**
YFITHD*YFCGREVGCSSDIKGVS*LYFISKDL
EL*KMPTSSIYF*KVLCGFI*S*AI*TLTLDLGF
KMPIVR*NNCEAGFTTQDELHFIN*LYLSDLLL
II*KWLDCGCFG*GDMEVGELLVK*EAM*TDKD
AKIKVSEVFHAFWTLSSQLTVNC*SKKSRHCMLL
LWLLFCDA*TT*THKLGRIFEQIFSVVCMTSVY
SWECHRIFCA*YMVSSLHSITSL*SSCC*E*CT
LKEKRKLHHSPILQCPCNELLSI*EAAPSLLQAW
CET*CLTCDQN*TIVQFGFCLLQNM*NCG**LI
CETNFESVTVLKKTLNVLQMKGLHGMLQCY*YN
LAFVMQIVNTSY*NIF**K

Sequence NM_006393

CTTGAGTGTTAGAGCTGAGTAGTTTTCCCAGAATCTCTAAGTCCTTTTTATGCTCTTTTATGAATGAATAGAATTAGTAAAAGATAAATAAATTTTTTCT
TTTGGATTTCTTAACCAGTGGAAAAAATGTTGACTTTAAAAGTTCATAAAATCAAATTTTGCTTAAGAATATGTTATTTCCACTTGTGAGGCCAGCCTGG
TAGACCTCTGGGATCCTTTTCTGTTCACTCACACACCACTGAGATAAGGAGTGAAGTGTGGGCTAAATAGGGCTGAGGCTTGGGCAAGGGCATTTCTGCC
AGAGCACCAGAGACGTCAGCATCTCAAGGGCACTGTGGTATGGAAAAGGACGCCACATGAGTAAATTTTAAAAATATAAATATTTTAAAGGGTAAAAATG
AGGGTCCCTGTATTTGAGGATATAAAAGATGAAACTGAAGAAGAAAAGATAGGGGAAGAAGAAAATGAAGAAGACCAGGTCTTCTATAAGCCTGTTATTG
AAGACTTAAGCATGGAATTGGCCAGAAAATGCACGGAACTCATTAGCGATATCCGTTATAAAGAAGAGTTTAAAAAGTCCAAGGATAAGTGTACATTTGT
GACTGACAGTCCTATGCTAAACCATGTAAAAAATATCGGTGCTTTTATTTCTGAGGCAAAATACAAAGGCACCATTAAAGCTGACCTTTCTAATTCTCTT
TATAAGCGGATGCCAGCCACAATTGACAGTGTTTTTGCAGGAGAAGTTACACAGCTCCAGAGTGAGGTGGCCTACAAGCAGAAACATGATGCTGCCAAAG
GATTCTCAGATTATGCCCACATGAAGGAGCCCCCTGAGGTTAAACATGCCATGGAGGTCAATAAACACCAGAGTAATATTTCTTATAGGAAAGACGTGCA
GGACACCCACACGTACAGTGCAGAACTTGACCGACCAGACATCAAGATGGCAACCCAGATCTCTAAGATCATAAGCAATGCAGAATACAAGAAAGGACAA
GGAATAATGAATAAAGAGCCCGCTGTAATTGGAAGACCAGATTTTGAACATGCCGTGGAAGCTTCTAAACTTTCTAGTCAAATTAAATACAAAGAAAAAT
TTGATAATGAAATGAAGGATAAGAAACATCATTACAATCCTCTTGAAAGTGCTTCTTTTAGGCAGAATCAGCTTGCTGCTACACTGGCGAGCAATGTGAA
GTACAAGAAAGACATTCAAAATATGCATGATCCAGTTTCAGATCTCCCAAATTTGTTGTTTTTAGACCATGTTTTGAAAGCCAGCAAAATGCTCAGCGGC
CGAGAATATAAAAAGCTCTTTGAGGAAAACAAAGGAATGTATCATTTTGATGCAGATGCTGTGGAACATCTGCACCATAAAGGCAATGCCGTCCTCCAAA
GTCAGGTGAAATATAAAGAAGAATATGAGAAAAATAAGGGAAAGCCAATGCTTGAATTTGTTGAGACACCATCATATCAAGCTTCAAAGGAGGCTCAAAA
GATGCAAAGTGAAAAAGTTTACAAAGAGGATTTTGAGAAGGAGATTAAAGGAAGGTCATCACTGGATTTAGACAAGACTCCAGAATTTTTACATGTAAAG
TACATCACCAACCTTCTGAGGGAGAAAGAATATAAAAAAGATTTGGAAAATGAGATAAAAGGGAAAGGAATGGAACTTAATTCAGAAGTTCTTGATATCC
AAAGAGCAAAGCGAGCCTCTGAAATGGCAAGTGAGAAAGAATACAAGAAAGACCTGGAGTCAATAATTAAAGGGAAAGGAATGCAAGCTGGCACTGACAC
CCTTGAAATGCAGCATGCCAAGAAGGCTGCAGAGATAGCGAGTGAGAAAGACTATAAAAGAGATCTGGAGACTGAAATTAAAGGGAAAGGGATGCAGGTG
AGCACAGACACTCTTGATGTCCAGAGAGCTAAGAAAGCATCCGAGATGGCCAGCCAGAAACAATACAAGAAGGACTTAGAAAATGAAATTAAAGGGAAAG
GAATGCAAGTGAGCATGGATATCCCAGATATCCTTCGAGCCAAGAGGACATCTGAAATCTATAGCCAGAGAAAGTATAAAGATGAAGCAGAGAAGATGCT
TTCTAACTATTCTACCATAGCAGATACTCCTGAAATTCAGAGAATTAAGACAACTCAACAAAACATTAGTGCGGTATTTTATAAGAAAGAAGTGGGAGCT
GGCACTGCAGTGAAAGATAGCCCAGAGATCGAACGAGTGAAGAAAAATCAGCAGAATATTAGTTCAGTGAAATACAAAGAAGAGATTAAACATGCAACAG
CCATTTCTGATCCTCCAGAACTAAAGAGAGTTAAAGAAAACCAGAAGAACATCAGCAATCTCCAGTATAAAGAGCAAAACTACAAGGCCACTCCGGTAAG
CATGACCCCGGAGATAGAGAGAGTGAGGCGAAACCAGGAGCAGCTGAGTGCGGTAAAATATAAGGGAGAACTTCAACGGGGAACTGCAATTTCTGATCCA
CCAGAGCTGAAGAGGGCAAAAGAAAACCAGAAAAACATCAGCAATGTTTATTACAGAGGTCAGCTGGGAAGAGCTACCACTTTAAGTGTAACTCCTGAAA
TGGAAAGAGTGAAGAAGAATCAAGAAAATATTAGCTCGGTAAAATATACCCAGGACCATAAACAGATGAAAGGTAGACCAAGTCTGATTTTAGATACACC
TGCTATGAGACATGTTAAAGAAGCACAAAATCATATTTCAATGGTAAAATACCATGAAGATTTTGAAAAAACAAAGGGGAGAGGCTTTACTCCCGTCGTG
GACGATCCTGTGACAGAGAGAGTGAGGAAGAACACCCAGGTGGTCAGCGATGCTGCCTATAAAGGGGTCCACCCTCACATCGTGGAGATGGACAGGAGAC
CTGGAATCATTGTTGACCTCAAAGTTTGGCGCACAGATCCTGGCTCCATCTTCGACCTTGATCCCCTGGAAGACAATATTCAGTCTAGAAGTCTCCATAT
GCTCTCTGAAAAGGCGAGTCACTATAGGCGACACTGGTCTCGATCCCATTCCAGCAGTACTTTCGGTACAGGTCTCGGAGACGACAGGTCAGAAATCTCC
GAGATTTACCCTAGCTTTTCATGCTGCAGTGAGGTAACAAGACCGTCTGATGAAGGAGCACCTGTTCTTCCCGGAGCCTATCAGCAAAGCCATTCCCAAG
GCTATGGCTACATGCACCAGACCAGTGTGTCATCCATGAGATCAATGCAGCATTCACCAAATCTAAGGACCTACCGAGCCATGTACGATTACAGTGCCCA
GGATGAAGACGAGGTCTCCTTTAGAGACGGCGACTACATCGTCAACGTGCAGCCTATTGACGATGGCTGGATGTACGGCACAGTGCAGAGAACAGGGAGA
ACAGGAATGCTCCCAGCGAATTACATTGAGTTTGTTAATTAATTATTTCTCCCTGCCCTTTGAGCTTTATTCTAATGTATCCCAAACCTAATCTTTTTAA
AAGATAGAAGATACTTTTAAGACAACTTGGCCATTATTTTACAATGATGTATCCTTCCTTTGACAATTAGACACACAGGTACCAGGAAGAAGGAATGACC
TCTGGGCTGAAAACAGCAGCATTTTCAGTAATTCCTACAAACAAAAATCTTTGTGTCTGGACACCTGGTGCTGCTAATTGTGTTCATGGTTTCCTTTGAT
TGGCTATTGAACCCTTCTGGGAAATGTATTTTTGTAGACTTTAATAGAGAAGTTGATTGTCCCTTAAATGTAGTGTGTGTTTGAAACTTCTTAGCTGTCA
CTTTGGAATCACCCCAAGCCAATTCTCTTAACTCTGTAATGCAGCCAATAATTTCAAACCCGTTTTGCTTTTGAGTCATGAGGCAATTTCCAATATTAGT
GAAAATTGCCCAATATAATAAGTGTAAACAGTGGCAGAAGGACAGTCTGGTTAAAATTATATTGACTGGTGGCCTTAGGGATCTAGAAACTTCTACTAAA
CAGAGAAATTTCCTTGTTCCCTAGGCTGACTGGTATCTATTTATTTCTCATTTGTACCAAGGCATCTCCTACTCTCCATTTATATTCTATGGACCCAAGT
CTATGCTCAGTTCCACAGAATGTCAGGACCAAATAACTTCACAGCTACTCTGCAAAGGGCAAATTATAATGTCATTGATATAATTTCCCTAGTAGCATTT
ACCCTGTTGCATGTCATGTAGATTCAAGCTTCTGTAACATAGGCAGCTGCACTGCGCGTTCCTATTATTGAAGCAAAAAGGGTGACTGATACCTAAAAGC
CCTTTCTTCCTCTAGTCGCCAGCTCATCAGAAAAACATACTTTGAAAAGATGCTTGAGATTTTCCTGCTGCATCGCACTCTAGTTTTGAAGGATTTACAT
CTTAGGAAATAACATGTATACTCTAGTAAATAAGCGATTTAGGTGTTCCATTGAACAGCTTTGATTAACTTAATGCCACCATTGATTTCAAAGTGAAGAA
AATGTAACAGAAGCCAGTGAAGCAATGGAAGCTGGAGTGTGACTGGAAAAATACTCAGCAAACAAAGTTACCAATTCCATACAGAGATGATCTGGTATCT
TCTTTTGGAAAATGGTATTCAAATTCTGGAATGGAAATCTAGCCACCAAAACGGGTTAATCAAAAGACGTCCTTTTCCATTTTTTTTTGCTTTTATTTTC
TAAATCATTTTTAAGGGAATGAAACAGGAATGTCATCAGAGATTTTTTAGTACAGGCCCAAGAGCCTGTTCTCTAAGAAAGAAATTGTTGCCATGTTTTG
ATTTTCGAATAAGTGACTTTGCAGGCTTTATGCTAGCCCTTGCTGGTGGGTCTTGAAATTTCATCCAGAGTCTGCAGTCCAGGTCACCAAGCCAGCGGCA
CCCGTCGGCAACCCTGTGTTTTTCTGATTGTGCCGTTTACTGTGACCTGCAACGGGGTGGCATTCACTTAGGGTCTGACTTCACAGCTATGACAAAACCG
AAAAAGCAAAACTGCAAAAAAGTACTAAGATGTACGGGTCTTGGGGATATCTGCCTTATATGTTATATTCAAGGAAATTAACAAAACATCCTGTAAAACA
TCGTTTAAGGAAACGTTTACTAGTCCAAAGGCCAAAGCTAATTTATTTCCACTTTAGAAAAGTTAGCACATGCTTTTGAAAATCTGTGATTTCATTTTAT
TAGGCTAAAAGGGTAAATAGGCTTTATTACACTGAAGCTGCATCTATATGTCACTGACATAAAGTTGAAAAAATAAATGCAGGCAAATAACTAGAGACTT
CTTTTAAGGGGGTTTGGCTGGTTTTCTCTCACTGAAATGGCCAGTCGTGATTAAAGTGATAAAACCCCATATCTGTTTTGGTATATTGTACACAAACCTA
CAAAAATAAACTGAACTTGCAATATTTTTGCAAAAAAATCTGTCGTTAAAACTGAGGATAAAATACCTGCTCAATTTTATTTTACTAAGTATATATTTAC
ATTTCACCCAGGCAGGCCATTTTCTTTTGTGATTATAAGAAAGAGTAGTTGTTGATTAAATTTTCAGACTAAATATAGGACAGGTACAATTTTGGATAAA
TAGCACATTTATAAGAACCGCAATGAAAACTGACTTGAAATAATGCTTGTAATCAGGAAAGTAATTTCATCCACCGATTTCAAAACCAGATTCACTGAGC
ATAAAAGTCAATACATATTTGAGGAATAAGTCTCCTAAAATTTTAAGCTTCACGTAATAATGTTTGCATAGCAAAATATTTCTGCTTCAAGCCTTTAGGA
ATTAAGATCTGATCAGAATTTAACTAAAGGGTAGTTGTTTTACAATGAAGACTAAAACTGAACAAGATGTTGCATGCTCTTGAGGCCATAATTTGGTAGT
GTTGGCAGTTGTTAATAAAGCTTGTCAGGATGTTAAGCATCTCAGGAGAAATATTGGAAAATTATATGTATAAAACCAAAGTGCTATTTTTAAAAGCATC
ATTTAAAAAAAAATGACATGCCTGAACAACTTTTCCACTTTCCACGTGCTTCCCTCCCACCTTTGGTTTGGCAACAGGTATCTCGTGCATGAAGCTGACA
GCTAAAGAAGATTTTAAAAATTGAGTTAAAGATGACTGTGTAAATGTCCAAGCACAGAGAGCATGCACCTGACTTTCTAAAGTTTGATGTGTTCTCAAGC
CTGACAGAAGCACAAGGAACAGTTTGATACACTTTTAAAAGGTTCTGAAAACAAAGCTGTATAGGGATCCTCTCTCTCTTGAGCAAAGTATAGCAACAGA
ATATATTGCTTTTGTTGTAAGCTTTTGTAGTACATGTTTTTACTAATAATTCTTGTTCTCTAGAAAGCTTTCTATTTCTAACCTATGGCAAAATGAATCC
TTCATGTCTTCTTGTTATTGTTTACACACTTGCAGTGTAGCCCAGTTTGAAATATTTATTTGGTTATCAACTGCCCATGGAGGAGGCTCTTGATGATCCC
AGGTCTCCTCGACCTCCATACACCACACAGGCATTTGTAAGCACAGTTTCCACAAGCACCTTGTAGGAATATGGATAAGATTAGACCAGCCCCTCTCTGT
CCACTGGGTTTATTTCTTGAAGAAGATGCAGATCTGGTTTTTCCAATGTGCCACAGTCTTTCCTTATCCTCTCCATGCTGAGCTTGACAACACTCTGGGA
ATGAGGAACAAGACTTTTTCTAAAAAGATAGTGGAAGTTCAAGGGATGTACCTCGTTTTCAGGTTCATCCATCTCCAGTGGAATGTTTTCAATAAAAGAT
GAAGAAAATGTGTGTGATCTTTAATAACACATCCCTATAGAAAGTGGATAAAAGATATACCAAAACTGTAATACAGATATATACAAATATAGGTGCCTTT
TTGATTACTCTTGTTTGTCTAGTATGCTCTTGGAAAGAAAACCAAGCAAGCAAGTTGCTGCCTATTCTATAGTAATATTTTATTACACATGATTGATATT
TTTGTGGTAGGGAAGTGGGATGCTCCTCAGATATTAAAGGTGTTAGCTGATTGTATTTTATCTCTAAAGATTTAGAACTTTAGAAAATGCCGACTTCTTC
CATCTATTTCTGAAAGGTTCTTTGTGGATTTATATAGAGTTGAGCTATATAAACATTAACTTTAGATTTGGGATTTAAAATGCCTATTGTAAGATAGAAT
AATTGTGAGGCTGGATTCACTACACAAGATGAACTTCACTTCATAAATTAATTATACCTTAGCGATTTGCTTCTGATAATCTAAAAGTGGCTAGATTGTG
GTTGTTTTGGTTAAGGTGATATGGAGGTGGGAGAGCTTTTAGTTAAGTAAGAAGCTATGTAAACTGACAAGGATGCTAAAATAAAAGTCTCTGAAGTATT
CCATGCCTTTTGGACCCTTTCCTCGCAACTAACTGTCAACTGTTGATCAAAAAAGTCAAGGCATTGTATGTTGCTTCTGTGGTTATTATTCTGTGATGCT
TAGACTACTTGAACCCATAAACTTGGAAGAATCTTTGAGCAAATTTTCTCAGTTGTCTGTATGACTTCAGTATATTCCTGGGAATGCCATAGGATTTTTT
GTGCTTGATACATGGTATCCAGTTTGCATAGTATCACTTCTTTGTAATCCAGTTGCTGTTAAGAATGATGTACTTTAAAGGAAAAGAGAAAACTGCATCA
CAGTCCCATTCTCCAGTGTCCATGCAATGAATTGCTGAGCATTTAGGAAGCAGCACCAAGTCTATTACAGGCATGGTGTGAAACTTGATGTTTGACCTGT
GATCAAAATTGAACCATTGTACAGTTTGGCTTCTGTTTGCTTCAAAATATGTAGAATTGTGGTTGATGATTAATTTGCGAGACTAACTTTGAGAGTGTAA
CAGTTTTGAAGAAAACATTGAATGTTTTGCAAATGAAGGGGCTTCACGGAATGTTACAATGTTACTAATATAATTTGGCTTTTGTTATGCAAATTGTTAA
CACCAGCTATTAAAATATATTTTAGTAGAAA
  • refseq_NEBL.F1 (forward primer)
  • refseq_NEBL.R1 (reverse primer)
  • Multiple exon skipping

Frame 0

LEC*S*VVFPESLSPFYALL*MNRISKR*INFF
FWIS*PVEKMLTLKVHKIKFCLRICYFHL*GQPG
RPLGSFSVHSHTTEIRSEVWAK*G*GLGKGISA
RAPETSASQGHCGMEKDAT*VNFKNINILKGKN
EGPCI*GYKR*N*RRKDRGRRK*RRPGLL*ACY*
RLKHGIGQKMHGTH*RYPL*RRV*KVQG*VYIC
D*QSYAKPCKKYRCFYF*GKIQRHH*S*PF*FS
L*ADASHN*QCFCRRSYTAPE*GGLQAET*CCQR
ILRLCPHEGAP*G*TCHGGQ*TPE*YFL*ERRA
GHPHVQCRT*PTRHQDGNPDL*DHKQCRIQERT
RNNE*RARCNWKTRF*TCRGSF*TF*SN*IQRKI
***NEG*ETSLQSS*KCFF*AESACCYTGEQCE
VQERHSKYA*SSFRSPKFVVFRPCFESQQNAQR
PRI*KAL*GKQRNVSF*CRCCGTSAP*RQCRPPK
SGEI*RRI*EK*GKANA*IC*DTIISSFKGGSK
DAK*KSLQRGF*EGD*RKVITGFRQDSRIFTCK
VHHQPSEGERI*KRFGK*DKRERNGT*FRSS*YP
KSKASL*NGK*ERIQERPGVNN*RERNASWH*H
P*NAACQEGCRDSE*ERL*KRSGD*N*RERDAG
EHRHS*CPES*ESIRDGQPETIQEGLRK*N*RER
NASEHGYPRYPSSQEDI*NL*PEKV*R*SREDA
F*LFYHSRYS*NSEN*DNSTKH*CGIL*ERSGS
WHCSER*PRDRTSEEKSAEY*FSEIQRRD*TCNS
HF*SSRTKES*RKPEEHQQSPV*RAKLQGHSGK
HDPGDRESEAKPGAAECGKI*GRTSTGNCNF*S
TRAEEGKRKPEKHQQCLLQRSAGKSYHFKCNS*N
GKSEEESRKY*LGKIYPGP*TDER*TKSDFRYT
CYETC*RSTKSYFNGKIP*RF*KNKGERLYSRR
GRSCDRESEEEHPGGQRCCL*RGPPSHRGDGQET
WNHC*PQSLAHRSWLHLRP*SPGRQYSV*KSPY
AL*KGESL*ATLVSIPFQQYFRYRSRRRQVRNL
RDLP*LFMLQ*GNKTV**RSTCSSRSLSAKPFPR
LWLHAPDQCVIHEINAAFTKSKDLPSHVRLQCP
G*RRGLL*RRRLHRQRAAY*RWLDVRHSAENRE
NRNAPSELH*VC*LIISPCPLSFILMYPKPNLFK
R*KILLRQLGHYFTMMYPSFDN*THRYQEEGMT
SGLKTAAFSVIPTNKNLCVWTPGAANCVHGFL*
LAIEPFWEMYFCRL**RS*LSLKCSVCLKLLSCH
FGITPSQFS*LCNAANNFKPVLLLSHEAISNIS
ENCPI**V*TVAEGQSG*NYIDWWP*GSRNFY*
TEKFPCSLG*LVSIYFSFVPRHLLLSIYILWTQV
YAQFHRMSGPNNFTATLQRANYNVIDIISLVAF
TLLHVM*IQASVT*AAALRVPIIEAKRVTDT*K
PFLPLVASSSEKHTLKRCLRFSCCIAL*F*RIYI
LGNNMYTLVNKRFRCSIEQL*LT*CHH*FQSEE
NVTEASEAMEAGV*LEKYSANKVTNSIQR*SGI
FFWKMVFKFWNGNLATKTG*SKDVLFHFFLLLFS
KSFLRE*NRNVIRDFLVQAQEPVL*ERNCCHVL
IFE*VTLQALC*PLLVGLEISSRVCSPGHQASG
TRRQPCVFLIVPFTVTCNGVAFT*GLTSQL*QNR
KSKTAKKY*DVRVLGISALYVIFKEINKTSCKT
SFKETFTSPKAKANLFPL*KS*HMLLKICDFIL
LG*KGK*ALLH*SCIYMSLT*S*KNKCRQITRDF
F*GGLAGFLSLKWPVVIKVIKPHICFGILYTNL
QK*TELAIFLQKNLSLKLRIKYLLNFILLSIYL
HFTQAGHFLL*L*ERVVVD*IFRLNIGQVQFWIN
STFIRTAMKTDLK*CL*SGK*FHPPISKPDSLS
IKVNTYLRNKSPKILSFT**CLHSKIFLLQAFR
N*DLIRI*LKGSCFTMKTKTEQDVACS*GHNLVV
LAVVNKACQDVKHLRRNIGKLYV*NQSAIFKSI
I*KKMTCLNNFSTFHVLPSHLWFGNRYLVHEAD
S*RRF*KLS*R*LCKCPSTESMHLTF*SLMCSQA
*QKHKEQFDTLLKGSENKAV*GSSLS*AKYSNR
IYCFCCKLL*YMFLLIILVL*KAFYF*PMAK*I
LHVFLLLFTHLQCSPV*NIYLVINCPWRRLLMIP
GLLDLHTPHRHL*AQFPQAPCRNMDKIRPAPLC
PLGLFLEEDADLVFPMCHSLSLSSPC*A*QHSG
NEEQDFF*KDSGSSRDVPRFQVHPSPVECFQ*KM
KKMCVIFNNTSL*KVDKRYTKTVIQIYTNIGAF
LITLVCLVCSWKENQASKLLPIL**YFITHD*Y
FCGREVGCSSDIKGVS*LYFISKDLEL*KMPTSS
IYF*KVLCGFI*S*AI*TLTLDLGFKMPIVR*N
NCEAGFTTQDELHFIN*LYLSDLLLII*KWLDC
GCFG*GDMEVGELLVK*EAM*TDKDAKIKVSEVF
HAFWTLSSQLTVNC*SKKSRHCMLLLWLLFCDA
*TT*THKLGRIFEQIFSVVCMTSVYSWECHRIF
CA*YMVSSLHSITSL*SSCC*E*CTLKEKRKLHH
SPILQCPCNELLSI*EAAPSLLQAWCET*CLTC
DQN*TIVQFGFCLLQNM*NCG**LICETNFESV
TVLKKTLNVLQMKGLHGMLQCY*YNLAFVMQIVN
TSY*NIF**K

Frame 1

LSVRAE*FSQNL*VLFMLFYE*IELVKDK*IFS
FGFLNQWKKC*L*KFIKSNFA*EYVISTCEASL
VDLWDPFLFTHTPLR*GVKCGLNRAEAWARAFLP
EHQRRQHLKGTVVWKRTPHE*ILKI*IF*RVKM
RVPVFEDIKDETEEEKIGEEENEEDQVFYKPVI
EDLSMELARKCTELISDIRYKEEFKKSKDKCTFV
TDSPMLNHVKNIGAFISEAKYKGTIKADLSNSL
YKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAK
GFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQ
DTHTYSAELDRPDIKMATQISKIISNAEYKKGQ
GIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEK
FDNEMKDKKHHYNPLESASFRQNQLAATLASNVK
YKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSG
REYKKLFEENKGMYHFDADAVEHLHHKGNAVLQ
SQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQK
MQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVK
YITNLLREKEYKKDLENEIKGKGMELNSEVLDI
QRAKRASEMASEKEYKKDLESIIKGKGMQAGTDT
LEMQHAKKAAEIASEKDYKRDLETEIKGKGMQV
STDTLDVQRAKKASEMASQKQYKKDLENEIKGK
GMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKML
SNYSTIADTPEIQRIKTTQQNISAVFYKKEVGA
GTAVKDSPEIERVKKNQQNISSVKYKEEIKHAT
AISDPPELKRVKENQKNISNLQYKEQNYKATPVS
MTPEIERVRRNQEQLSAVKYKGELQRGTAISDP
PELKRAKENQKNISNVYYRGQLGRATTLSVTPE
MERVKKNQENISSVKYTQDHKQMKGRPSLILDTP
AMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVV
DDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRR
PGIIVDLKVWRTDPGSIFDLDPLEDNIQSRSLHM
LSEKASHYRRHWSRSHSSSTFGTGLGDDRSEIS
EIYPSFSCCSEVTRPSDEGAPVLPGAYQQSHSQ
GYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQ
DEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGR
TGMLPANYIEFVN*LFLPAL*ALF*CIPNLIFL
KDRRYF*DNLAIILQ*CILPLTIRHTGTRKKE*P
LG*KQQHFQ*FLQTKIFVSGHLVLLIVFMVSFD
WLLNPSGKCIFVDFNREVDCPLNVVCV*NFLAV
TLESPQANSLNSVMQPIISNPFCF*VMRQFPILV
KIAQYNKCKQWQKDSLVKIILTGGLRDLETSTK
QRNFLVP*ADWYLFISHLYQGISYSPFIFYGPK
SMLSSTECQDQITSQLLCKGQIIMSLI*FP**HL
PCCMSCRFKLL*HRQLHCAFLLLKQKG*LIPKS
PFFL*SPAHQKNIL*KDA*DFPAASHSSFEGFT
S*EITCIL**ISDLGVPLNSFD*LNATIDFKVKK
M*QKPVKQWKLECDWKNTQQTKLPIPYRDDLVS
SFGKWYSNSGMEI*PPKRVNQKTSFSIFFCFYF
LNHF*GNETGMSSEIF*YRPKSLFSKKEIVAMF*
FSNK*LCRLYASPCWWVLKFHPESAVQVTKPAA
PVGNPVFF*LCRLL*PATGWHSLRV*LHSYDKT
EKAKLQKSTKMYGSWGYLPYMLYSRKLTKHPVKH
RLRKRLLVQRPKLIYFHFRKVSTCF*KSVISFY
*AKRVNRLYYTEAASICH*HKVEKINAGK*LET
SFKGVWLVFSH*NGQS*LK**NPISVLVYCTQTY
KNKLNLQYFCKKICR*N*G*NTCSILFY*VYIY
ISPRQAIFFCDYKKE*LLIKFSD*I*DRYNFG*
IAHL*EPQ*KLT*NNACNQESNFIHRFQNQIH*A
*KSIHI*GISLLKF*ASRNNVCIAKYFCFKPLG
IKI*SEFN*RVVVLQ*RLKLNKMLHALEAIIW*
CWQLLIKLVRMLSISGEILENYMYKTKVLFLKAS
FKKK*HA*TTFPLSTCFPPTFGLATGISCMKLT
AKEDFKN*VKDDCVNVQAQRACT*LSKV*CVLK
PDRSTRNSLIHF*KVLKTKLYRDPLSLEQSIATE
YIAFVVSFCSTCFY**FLFSRKLSISNLWQNES
FMSSCYCLHTCSVAQFEIFIWLSTAHGGGS**S
QVSSTSIHHTGICKHSFHKHLVGIWIRLDQPLSV
HWVYFLKKMQIWFFQCATVFPYPLHAELDNTLG
MRNKTFSKKIVEVQGMYLVFRFIHLQWNVFNKR
*RKCV*SLITHPYRKWIKDIPKL*YRYIQI*VPF
*LLLFV*YALGKKTKQASCCLFYSNILLHMIDI
FVVGKWDAPQILKVLADCILSLKI*NFRKCRLL
PSISERFFVDLYRVELYKH*L*IWDLKCLL*DRI
IVRLDSLHKMNFTS*INYTLAICF**SKSG*IV
VVLVKVIWRWESF*LSKKLCKLTRMLK*KSLKY
SMPFGPFPRN*LSTVDQKSQGIVCCFCGYYSVML
RLLEPINLEESLSKFSQLSV*LQYIPGNAIGFF
VLDTWYPVCIVSLLCNPVAVKNDVL*RKRENCI
TVPFSSVHAMNC*AFRKQHQVYYRHGVKLDV*PV
IKIEPLYSLASVCFKICRIVVDD*FARLTLRV*
QF*RKH*MFCK*RGFTECYNVTNIIWLLLCKLL
TPAIKIYFSR

Frame 2

*VLELSSFPRISKSFLCSFMNE*N**KINKFFL
LDFLTSGKNVDFKSS*NQILLKNMLFPLVRPAW
*TSGILFCSLTHH*DKE*SVG*IGLRLGQGHFC
QSTRDVSISRALWYGKGRHMSKF*KYKYFKG*K*
GSLYLRI*KMKLKKKR*GKKKMKKTRSSISLLL
KT*AWNWPENARNSLAISVIKKSLKSPRISVHL
*LTVLC*TM*KISVLLFLRQNTKAPLKLTFLILF
ISGCQPQLTVFLQEKLHSSRVRWPTSRNMMLPK
DSQIMPT*RSPLRLNMPWRSINTRVIFLIGKTC
RTPTRTVQNLTDQTSRWQPRSLRS*AMQNTRKDK
E**IKSPL*LEDQILNMPWKLLNFLVKLNTKKN
LIMK*RIRNIITILLKVLLLGRISLLLHWRAM*
STRKTFKICMIQFQISQICCF*TMF*KPAKCSAA
ENIKSSLRKTKECIILMQMLWNICTIKAMPSSK
VR*NIKKNMRKIRESQCLNLLRHHHIKLQRRLK
RCKVKKFTKRILRRRLKEGHHWI*TRLQNFYM*S
TSPTF*GRKNIKKIWKMR*KGKEWNLIQKFLIS
KEQSEPLKWQVRKNTRKTWSQ*LKGKECKLALT
PLKCSMPRRLQR*RVRKTIKEIWRLKLKGKGCR*
AQTLLMSRELRKHPRWPARNNTRRT*KMKLKGK
ECK*AWISQISFEPRGHLKSIARESIKMKQRRC
FLTILP*QILLKFRELRQLNKTLVRYFIRKKWEL
ALQ*KIAQRSNE*RKISRILVQ*NTKKRLNMQQ
PFLILQN*RELKKTRRTSAISSIKSKTTRPLR*
A*PRR*RE*GETRSS*VR*NIRENFNGELQFLIH
QS*RGQKKTRKTSAMFITEVSWEELPL*V*LLK
WKE*RRIKKILAR*NIPRTINR*KVDQV*F*IH
LL*DMLKKHKIIFQW*NTMKILKKQRGEALLPSW
TIL*QRE*GRTPRWSAMLPIKGSTLTSWRWTGD
LESLLTSKFGAQILAPSSTLIPWKTIFSLEVSI
CSLKRRVTIGDTGLDPIPAVLSVQVSETTGQKSP
RFTLAFHAAVR*QDRLMKEHLFFPEPISKAIPK
AMATCTRPVCHP*DQCSIHQI*GPTEPCTITVP
RMKTRSPLETATTSSTCSLLTMAGCTAQCREQGE
QECSQRITLSLLINYFSLPFELYSNVSQT*SF*
KIEDTFKTTWPLFYNDVSFL*QLDTQVPGRRND
LWAENSSIFSNSYKQKSLCLDTWCC*LCSWFPLI
GY*TLLGNVFL*TLIEKLIVP*M*CVFETS*LS
LWNHPKPILLTL*CSQ*FQTRFAFES*GNFQY*
*KLPNIISVNSGRRTVWLKLY*LVALGI*KLLLN
REISLFPRLTGIYLFLICTKASPTLHLYSMDPS
LCSVPQNVRTK*LHSYSAKGKL*CH*YNFPSSI
YPVACHVDSSFCNIGSCTARSYY*SKKGD*YLKA
LSSSSRQLIRKTYFEKMLEIFLLHRTLVLKDLH
LRK*HVYSSK*AI*VFH*TALINLMPPLISK*R
KCNRSQ*SNGSWSVTGKILSKQSYQFHTEMIWYL
LLENGIQILEWKSSHQNGLIKRRPFPFFFAFIF
*IIFKGMKQECHQRFFSTGPRACSLRKKLLPCF
DFRISDFAGFMLALAGGS*NFIQSLQSRSPSQRH
PSATLCFSDCAVYCDLQRGGIHLGSDFTAMTKP
KKQNCKKVLRCTGLGDICLICYIQGN*QNIL*N
IV*GNVY*SKGQS*FISTLEKLAHAFENL*FHFI
RLKG*IGFITLKLHLYVTDIKLKK*MQANN*RL
LLRGFGWFSLTEMASRD*SDKTPYLFWYIVHKP
TKIN*TCNIFAKKSVVKTEDKIPAQFYFTKYIFT
FHPGRPFSFVIIRKSSC*LNFQTKYRTGTILDK
*HIYKNRNEN*LEIMLVIRKVISSTDFKTRFTE
HKSQYIFEE*VS*NFKLHVIMFA*QNISASSL*E
LRSDQNLTKG*LFYNED*N*TRCCMLLRP*FGS
VGSC**SLSGC*ASQEKYWKIICIKPKCYF*KH
HLKKNDMPEQLFHFPRASLPPLVWQQVSRA*S*Q
LKKILKIELKMTV*MSKHREHAPDFLKFDVFSS
LTEAQGTV*YTFKRF*KQSCIGILSLLSKV*QQ
NILLLL*AFVVHVFTNNSCSLESFLFLTYGKMNP
SCLLVIVYTLAV*PSLKYLFGYQLPMEEALDDP
RSPRPPYTTQAFVSTVSTSTL*EYG*D*TSPSL
STGFIS*RRCRSGFSNVPQSFLILSMLSLTTLWE
*GTRLFLKR*WKFKGCTSFSGSSISSGMFSIKD
EENVCDL**HIPIESG*KIYQNCNTDIYKYRCL
FDYSCLSSMLLERKPSKQVAAYSIVIFYYT*LIF
LW*GSGMLLRY*RC*LIVFYL*RFRTLENADFF
HLFLKGSLWIYIELSYININFRFGI*NAYCKIE
*L*GWIHYTR*TSLHKLIIP*RFASDNLKVARLW
LFWLR*YGGGRAFS*VRSYVN*QGC*NKSL*SI
PCLLDPFLATNCQLLIKKVKALYVASVVIIL*C
LDYLNP*TWKNL*ANFLSCLYDFSIFLGMP*DFL
CLIHGIQFA*YHFFVIQLLLRMMYFKGKEKTAS
QSHSPVSMQ*IAEHLGSSTKSITGMV*NLMFDL
*SKLNHCTVWLLFASKYVELWLMINLRD*L*ECN
SFEENIECFANEGASRNVTMLLI*FGFCYANC*
HQLLKYILVE

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