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Sequences

Sequence NM_016250

CGGCCCCCCGCATTCCCCGCCCCCACCTCCCCGCCTTGTTGTCCAACTTCTCCCGGAGCAGCCGGAGAGCAGGCGTCGGGACGCAGCAAAGAGAGGAGAG
ACCCCAGAGTCAGAAGGAGTGAGAACCCTGACCCCTAATCCCACTGCATCCAGCCAATAGGAGCCCAGCCACCATGGCGGAGCTGCAGGAGGTGCAGATC
ACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGACTCACTCTGTGGAGACACCATACGGCTCTGTCACTTTCACTGTCTATGGCA
CCCCCAAACCCAAACGCCCAGCGATCCTTACCTACCACGATGTGGGACTCAACTATAAATCTTGCTTCCAGCCACTGTTTCAGTTCGAGGACATGCAGGA
AATCATTCAGAACTTTGTGCGGGTTCATGTGGATGCCCCTGGAATGGAAGAGGGAGCCCCTGTGTTCCCTTTGGGATATCAGTACCCATCTCTGGACCAG
CTTGCAGACATGATCCCTTGCGTCCTGCAGTACCTAAATTTCTCTACAATAATTGGAGTTGGTGTTGGAGCTGGAGCCTACATCCTGGCGAGATATGCTC
TTAACCACCCGGACACTGTTGAAGGTCTTGTCCTCATCAACATTGATCCCAATGCCAAGGGTTGGATGGATTGGGCAGCCCACAAGCTAACAGGCCTCAC
CTCTTCCATTCCGGAGATGATCCTTGGACATCTTTTCAGCCAGGAAGAGCTCTCTGGAAATTCTGAGTTGATACAAAAGTACAGAAATATCATTACACAT
GCACCCAACCTGGATAACATTGAATTGTACTGGAACAGCTACAACAACCGCCGAGACCTGAACTTTGAGCGTGGAGGTGATATCACCCTCAGGTGTCCTG
TGATGCTGGTGGTAGGAGACCAAGCACCTCATGAAGATGCAGTGGTGGAATGTAACTCAAAACTGGACCCCACCCAGACCTCGTTCCTCAAGATGGCTGA
CTCCGGAGGTCAGCCCCAGCTGACTCAGCCAGGCAAGCTGACCGAGGCCTTCAAGTACTTCCTGCAAGGCATGGGCTACATGGCCTCATCCTGCATGACT
CGCCTGTCCCGGTCTCGTACAGCCTCTCTGACCAGTGCAGCATCCGTTGATGGCAACCGGTCCCGCTCTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAA
CTCTTTCTTCGGGGCCCCCGGGGCACACCATGGAGGTCTCCTGTTGAATGGCCCTTGTTGCCCTAGAGTGGGACCCAGCCCTCACCTCCCCCAGAGCTAA
CCTGGGAGGTGCTGAAGGGGCATTGGGCCACCGTAAGCAAGGGAAAAAGGGCAGATCATGCGGGGAGATGACCTTGATCTTTGATTGCTACCCTAACCTT
GACCTTTAACCCGTGATTCCCCCCAGCTCCTGGAAGAGATGTCCTAATATCTCTTAGGGACCCAGACCCCTAAATTCTCCTCCTCCCCCATTTTGATGTT
AAGGTGGAGAGGGCATATGCATCCTCTGTCCTGATCTAGGTGTCTATAGCTGAGGGGTAAGAGGTTGTTGTAGTTGTCCTGGTGCCTCCATCAGACTCTC
CCTACTTGTCCCATATTTGCAAGGGGAGGGGATTTGGGGCTGGGGCTCCATTCACCAAAGCTGAGGTGGCTTCTCATTAACCCTTTAGGACTCTGAAGGG
TATGGACCTACGTGAATGTGTGTCAGGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCAGGATGTGATAGAAACATCCAGTGTAAAAAGGAAGTTGGAATG
GGAGTTGGCGGGCAGTGAACGAGTGTGGGGAAGGATTGGTGCTGGGGCAACAGGAAGGGGCCTGGGGCCGTTTGGCTGCACTAACTTTGGTAGCTCAGTG
TGCATCTAGAGTGGGACTGGGGAGGGAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTGGCATAGGGTGGAAAGGGCTACCCTGGGGCTCTGACCACACTG
TAGTATGTGTGGAGGGTGCCCTCCCGTCTCCCACAACTTCTGCTATAACAATAAACTGTAGAGGAATCTGAGTACCGTTA
  • refseq_NDRG2.F1 (forward primer)
  • refseq_NDRG2.R1 (reverse primer)
  • Single exon skipping

Frame 0

RPPAFPAPTSPPCCPTSPGAAGEQASGRSKERR
DPRVRRSENPDP*SHCIQPIGAQPPWRSCRRCRS
QRRSHCCQDRRLRRPRLTLWRHHTALSLSLSMA
PPNPNAQRSLPTTMWDSTINLASSHCFSSRTCR
KSFRTLCGFMWMPLEWKREPLCSLWDISTHLWTS
LQT*SLASCST*ISLQ*LELVLELEPTSWRDML
LTTRTLLKVLSSSTLIPMPRVGWIGQPTS*QAS
PLPFRR*SLDIFSARKSSLEILS*YKSTEISLHM
HPTWITLNCTGTATTTAET*TLSVEVISPSGVL
*CWW*ETKHLMKMQWWNVTQNWTPPRPRSSRWL
TPEVSPS*LSQAS*PRPSSTSCKAWATWPHPA*L
ACPGLVQPL*PVQHPLMATGPALAPCPRAASLE
LFLRGPRGTPWRSPVEWPLLP*SGTQPSPPPEL
TWEVLKGHWATVSKGKRADHAGR*P*SLIATLTL
TFNP*FPPAPGRDVLISLRDPDP*ILLLPHFDV
KVERAYASSVLI*VSIAEG*EVVVVVLVPPSDS
PYLSHICKGRGFGAGAPFTKAEVASH*PFRTLKG
MDLRECVSGGDLLVG*WSSGCDRNIQCKKEVGM
GVGGQ*TSVGKDWCWGNRKGPGAVWLH*LW*LS
VHLEWDWGGS*AWAGLLGAWHRVERATLGL*PHC
SMCGGCPPVSHNFCYNNKL*RNLSTV

Frame 1

GPPHSPPPPPRLVVQLLPEQPESRRRDAAKRGE
TPESEGVRTLTPNPTASSQ*EPSHHGGAAGGAD
HRGEATVARTDA*GGQDSLCGDTIRLCHFHCLWH
PQTQTPSDPYLPRCGTQL*ILLPATVSVRGHAG
NHSELCAGSCGCPWNGRGSPCVPFGISVPISGP
ACRHDPLRPAVPKFLYNNWSWCWSWSLHPGEICS
*PPGHC*RSCPHQH*SQCQGLDGLGSPQANRPH
LFHSGDDPWTSFQPGRALWKF*VDTKVQKYHYT
CTQPG*H*IVLEQLQQPPRPEL*AWR*YHPQVSC
DAGGRRPSTS*RCSGGM*LKTGPHPDLVPQDG*
LRRSAPADSARQADRGLQVLPARHGLHGLILHD
SPVPVSYSLSDQCSIR*WQPVPLSHPVPEQRVWN
SFFGAPGAHHGGLLLNGPCCPRVGPSPHLPQS*
PGRC*RGIGPP*AREKGQIMRGDDLDL*LLP*P
*PLTRDSPQLLEEMS*YLLGTQTPKFSSSPILML
RWRGHMHPLS*SRCL*LRGKRLL*LSWCLHQTL
PTCPIFARGGDLGLGLHSPKLRWLLINPLGL*R
VWTYVNVCQGETCWWVSGPQDVIETSSVKRKLEW
ELAGSERVWGRIGAGATGRGLGPFGCTNFGSSV
CI*SGTGEGAKLGLGCLGLGIGWKGLPWGSDHT
VVCVEGALPSPTTSAITINCRGI*VPL

Frame 2

APRIPRPHLPALLSNFSRSSRRAGVGTQQREER
PQSQKE*EP*PLIPLHPANRSPATMAELQEVQI
TEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYG
TPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQE
IIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQ
LADMIPCVLQYLNFSTIIGVGVGAGAYILARYA
LNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLT
SSIPEMILGHLFSQEELSGNSELIQKYRNIITH
APNLDNIELYWNSYNNRRDLNFERGGDITLRCP
VMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMAD
SGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMT
RLSRSRTASLTSAASVDGNRSRSRTLSQSSESG
TLSSGPPGHTMEVSC*MALVALEWDPALTSPRAN
LGGAEGALGHRKQGKKGRSCGEMTLIFDCYPNL
DL*PVIPPSSWKRCPNIS*GPRPLNSPPPPF*C
*GGEGICILCPDLGVYS*GVRGCCSCPGASIRLS
LLVPYLQGEGIWGWGSIHQS*GGFSLTL*DSEG
YGPT*MCVRGRLAGGLVVLRM**KHPV*KGSWN
GSWRAVNECGEGLVLGQQEGAWGRLAALTLVAQC
ASRVGLGRELSLGWAAWGLA*GGKGYPGALTTL
*YVWRVPSRLPQLLL*Q*TVEESEYR

Sequence NM_201541

GGGTCTGCGGGAAGCCCGAGCCGGGGCGGGCCCGAGTCAAAGGCAAGTGAAGGTGGAAGCGGCCGCGGCGGCAGCAGACCCCAGAGTCAGAAGGAGTGAG
AACCCTGACCCCTAATCCCACTGCATCCAGCCAATAGGAGCCCAGCCACCATGGCGGAGCTGCAGGAGGTGCAGATCACAGAGGAGAAGCCACTGTTGCC
AGGACAGACGCCTGAGGCGGCCAAGACTCACTCTGTGGAGACACCATACGGCTCTGTCACTTTCACTGTCTATGGCACCCCCAAACCCAAACGCCCAGCG
ATCCTTACCTACCACGATGTGGGACTCAACTATAAATCTTGCTTCCAGCCACTGTTTCAGTTCGAGGACATGCAGGAAATCATTCAGAACTTTGTGCGGG
TTCATGTGGATGCCCCTGGAATGGAAGAGGGAGCCCCTGTGTTCCCTTTGGGATATCAGTACCCATCTCTGGACCAGCTTGCAGACATGATCCCTTGCGT
CCTGCAGTACCTAAATTTCTCTACAATAATTGGAGTTGGTGTTGGAGCTGGAGCCTACATCCTGGCGAGATATGCTCTTAACCACCCGGACACTGTTGAA
GGTCTTGTCCTCATCAACATTGATCCCAATGCCAAGGGTTGGATGGATTGGGCAGCCCACAAGCTAACAGGCCTCACCTCTTCCATTCCGGAGATGATCC
TTGGACATCTTTTCAGCCAGGAAGAGCTCTCTGGAAATTCTGAGTTGATACAAAAGTACAGAAATATCATTACACATGCACCCAACCTGGATAACATTGA
ATTGTACTGGAACAGCTACAACAACCGCCGAGACCTGAACTTTGAGCGTGGAGGTGATATCACCCTCAGGTGTCCTGTGATGCTGGTGGTAGGAGACCAA
GCACCTCATGAAGATGCAGTGGTGGAATGTAACTCAAAACTGGACCCCACCCAGACCTCGTTCCTCAAGATGGCTGACTCCGGAGGTCAGCCCCAGCTGA
CTCAGCCAGGCAAGCTGACCGAGGCCTTCAAGTACTTCCTGCAAGGCATGGGCTACATGGCCTCATCCTGCATGACTCGCCTGTCCCGGTCTCGTACAGC
CTCTCTGACCAGTGCAGCATCCGTTGATGGCAACCGGTCCCGCTCTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGG
CACACCATGGAGGTCTCCTGTTGAATGGCCCTTGTTGCCCTAGAGTGGGACCCAGCCCTCACCTCCCCCAGAGCTAACCTGGGAGGTGCTGAAGGGGCAT
TGGGCCACCGTAAGCAAGGGAAAAAGGGCAGATCATGCGGGGAGATGACCTTGATCTTTGATTGCTACCCTAACCTTGACCTTTAACCCGTGATTCCCCC
CAGCTCCTGGAAGAGATGTCCTAATATCTCTTAGGGACCCAGACCCCTAAATTCTCCTCCTCCCCCATTTTGATGTTAAGGTGGAGAGGGCATATGCATC
CTCTGTCCTGATCTAGGTGTCTATAGCTGAGGGGTAAGAGGTTGTTGTAGTTGTCCTGGTGCCTCCATCAGACTCTCCCTACTTGTCCCATATTTGCAAG
GGGAGGGGATTTGGGGCTGGGGCTCCATTCACCAAAGCTGAGGTGGCTTCTCATTAACCCTTTAGGACTCTGAAGGGTATGGACCTACGTGAATGTGTGT
CAGGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCAGGATGTGATAGAAACATCCAGTGTAAAAAGGAAGTTGGAATGGGAGTTGGCGGGCAGTGAACGAG
TGTGGGGAAGGATTGGTGCTGGGGCAACAGGAAGGGGCCTGGGGCCGTTTGGCTGCACTAACTTTGGTAGCTCAGTGTGCATCTAGAGTGGGACTGGGGA
GGGAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTGGCATAGGGTGGAAAGGGCTACCCTGGGGCTCTGACCACACTGTAGTATGTGTGGAGGGTGCCCTC
CCGTCTCCCACAACTTCTGCTATAACAATAAACTGTAGAGGAATCTGAGTACCGTTA
  • refseq_NDRG2.F1 (forward primer)
  • refseq_NDRG2.R1 (reverse primer)
  • Single exon skipping

Frame 0

GSAGSPSRGGPESKASEGGSGRGGSRPQSQKE*
EP*PLIPLHPANRSPATMAELQEVQITEEKPLLP
GQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPA
ILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVR
VHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCV
LQYLNFSTIIGVGVGAGAYILARYALNHPDTVE
GLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMI
LGHLFSQEELSGNSELIQKYRNIITHAPNLDNIE
LYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQ
APHEDAVVECNSKLDPTQTSFLKMADSGGQPQL
TQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTA
SLTSAASVDGNRSRSRTLSQSSESGTLSSGPPG
HTMEVSC*MALVALEWDPALTSPRANLGGAEGA
LGHRKQGKKGRSCGEMTLIFDCYPNLDL*PVIPP
SSWKRCPNIS*GPRPLNSPPPPF*C*GGEGICI
LCPDLGVYS*GVRGCCSCPGASIRLSLLVPYLQ
GEGIWGWGSIHQS*GGFSLTL*DSEGYGPT*MCV
RGRLAGGLVVLRM**KHPV*KGSWNGSWRAVNE
CGEGLVLGQQEGAWGRLAALTLVAQCASRVGLG
RELSLGWAAWGLA*GGKGYPGALTTL*YVWRVPS
RLPQLLL*Q*TVEESEYR

Frame 1

GLREARAGAGPSQRQVKVEAAAAAADPRVRRSE
NPDP*SHCIQPIGAQPPWRSCRRCRSQRRSHCC
QDRRLRRPRLTLWRHHTALSLSLSMAPPNPNAQR
SLPTTMWDSTINLASSHCFSSRTCRKSFRTLCG
FMWMPLEWKREPLCSLWDISTHLWTSLQT*SLA
SCST*ISLQ*LELVLELEPTSWRDMLLTTRTLLK
VLSSSTLIPMPRVGWIGQPTS*QASPLPFRR*S
LDIFSARKSSLEILS*YKSTEISLHMHPTWITL
NCTGTATTTAET*TLSVEVISPSGVL*CWW*ETK
HLMKMQWWNVTQNWTPPRPRSSRWLTPEVSPS*
LSQAS*PRPSSTSCKAWATWPHPA*LACPGLVQ
PL*PVQHPLMATGPALAPCPRAASLELFLRGPRG
TPWRSPVEWPLLP*SGTQPSPPPELTWEVLKGH
WATVSKGKRADHAGR*P*SLIATLTLTFNP*FP
PAPGRDVLISLRDPDP*ILLLPHFDVKVERAYAS
SVLI*VSIAEG*EVVVVVLVPPSDSPYLSHICK
GRGFGAGAPFTKAEVASH*PFRTLKGMDLRECV
SGGDLLVG*WSSGCDRNIQCKKEVGMGVGGQ*TS
VGKDWCWGNRKGPGAVWLH*LW*LSVHLEWDWG
GS*AWAGLLGAWHRVERATLGL*PHCSMCGGCP
PVSHNFCYNNKL*RNLSTV

Frame 2

VCGKPEPGRARVKGK*RWKRPRRQQTPESEGVR
TLTPNPTASSQ*EPSHHGGAAGGADHRGEATVA
RTDA*GGQDSLCGDTIRLCHFHCLWHPQTQTPS
DPYLPRCGTQL*ILLPATVSVRGHAGNHSELCAG
SCGCPWNGRGSPCVPFGISVPISGPACRHDPLR
PAVPKFLYNNWSWCWSWSLHPGEICS*PPGHC*
RSCPHQH*SQCQGLDGLGSPQANRPHLFHSGDDP
WTSFQPGRALWKF*VDTKVQKYHYTCTQPG*H*
IVLEQLQQPPRPEL*AWR*YHPQVSCDAGGRRP
STS*RCSGGM*LKTGPHPDLVPQDG*LRRSAPAD
SARQADRGLQVLPARHGLHGLILHDSPVPVSYS
LSDQCSIR*WQPVPLSHPVPEQRVWNSFFGAPG
AHHGGLLLNGPCCPRVGPSPHLPQS*PGRC*RGI
GPP*AREKGQIMRGDDLDL*LLP*P*PLTRDSP
QLLEEMS*YLLGTQTPKFSSSPILMLRWRGHMH
PLS*SRCL*LRGKRLL*LSWCLHQTLPTCPIFAR
GGDLGLGLHSPKLRWLLINPLGL*RVWTYVNVC
QGETCWWVSGPQDVIETSSVKRKLEWELAGSER
VWGRIGAGATGRGLGPFGCTNFGSSVCI*SGTGE
GAKLGLGCLGLGIGWKGLPWGSDHTVVCVEGAL
PSPTTSAITINCRGI*VPL

Sequence NM_201538

GGGTCTGCGGGAAGCCCGAGCCGGGGCGGGCCCGAGTCAAAGGCAAGTGAAGGTGGAAGCGGCCGCGGCGGCAGCAGGCCACCATGGCGGAGCTGCAGGA
GGTGCAGATCACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGACTCACTCTGTGGAGACACCATACGGCTCTGTCACTTTCACT
GTCTATGGCACCCCCAAACCCAAACGCCCAGCGATCCTTACCTACCACGATGTGGGACTCAACTATAAATCTTGCTTCCAGCCACTGTTTCAGTTCGAGG
ACATGCAGGAAATCATTCAGAACTTTGTGCGGGTTCATGTGGATGCCCCTGGAATGGAAGAGGGAGCCCCTGTGTTCCCTTTGGGATATCAGTACCCATC
TCTGGACCAGCTTGCAGACATGATCCCTTGCGTCCTGCAGTACCTAAATTTCTCTACAATAATTGGAGTTGGTGTTGGAGCTGGAGCCTACATCCTGGCG
AGATATGCTCTTAACCACCCGGACACTGTTGAAGGTCTTGTCCTCATCAACATTGATCCCAATGCCAAGGGTTGGATGGATTGGGCAGCCCACAAGCTAA
CAGGCCTCACCTCTTCCATTCCGGAGATGATCCTTGGACATCTTTTCAGCCAGGAAGAGCTCTCTGGAAATTCTGAGTTGATACAAAAGTACAGAAATAT
CATTACACATGCACCCAACCTGGATAACATTGAATTGTACTGGAACAGCTACAACAACCGCCGAGACCTGAACTTTGAGCGTGGAGGTGATATCACCCTC
AGGTGTCCTGTGATGCTGGTGGTAGGAGACCAAGCACCTCATGAAGATGCAGTGGTGGAATGTAACTCAAAACTGGACCCCACCCAGACCTCGTTCCTCA
AGATGGCTGACTCCGGAGGTCAGCCCCAGCTGACTCAGCCAGGCAAGCTGACCGAGGCCTTCAAGTACTTCCTGCAAGGCATGGGCTACATGGCCTCATC
CTGCATGACTCGCCTGTCCCGGTCTCGTACAGCCTCTCTGACCAGTGCAGCATCCGTTGATGGCAACCGGTCCCGCTCTCGCACCCTGTCCCAGAGCAGC
GAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGGCACACCATGGAGGTCTCCTGTTGAATGGCCCTTGTTGCCCTAGAGTGGGACCCAGCCCTCACCTCCC
CCAGAGCTAACCTGGGAGGTGCTGAAGGGGCATTGGGCCACCGTAAGCAAGGGAAAAAGGGCAGATCATGCGGGGAGATGACCTTGATCTTTGATTGCTA
CCCTAACCTTGACCTTTAACCCGTGATTCCCCCCAGCTCCTGGAAGAGATGTCCTAATATCTCTTAGGGACCCAGACCCCTAAATTCTCCTCCTCCCCCA
TTTTGATGTTAAGGTGGAGAGGGCATATGCATCCTCTGTCCTGATCTAGGTGTCTATAGCTGAGGGGTAAGAGGTTGTTGTAGTTGTCCTGGTGCCTCCA
TCAGACTCTCCCTACTTGTCCCATATTTGCAAGGGGAGGGGATTTGGGGCTGGGGCTCCATTCACCAAAGCTGAGGTGGCTTCTCATTAACCCTTTAGGA
CTCTGAAGGGTATGGACCTACGTGAATGTGTGTCAGGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCAGGATGTGATAGAAACATCCAGTGTAAAAAGGA
AGTTGGAATGGGAGTTGGCGGGCAGTGAACGAGTGTGGGGAAGGATTGGTGCTGGGGCAACAGGAAGGGGCCTGGGGCCGTTTGGCTGCACTAACTTTGG
TAGCTCAGTGTGCATCTAGAGTGGGACTGGGGAGGGAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTGGCATAGGGTGGAAAGGGCTACCCTGGGGCTCT
GACCACACTGTAGTATGTGTGGAGGGTGCCCTCCCGTCTCCCACAACTTCTGCTATAACAATAAACTGTAGAGGAATCTGAGTACCGTTA
  • refseq_NDRG2.F1 (forward primer)
  • refseq_NDRG2.R1 (reverse primer)
  • Single exon skipping

Frame 0

GSAGSPSRGGPESKASEGGSGRGGSRPPWRSCR
RCRSQRRSHCCQDRRLRRPRLTLWRHHTALSLSL
SMAPPNPNAQRSLPTTMWDSTINLASSHCFSSR
TCRKSFRTLCGFMWMPLEWKREPLCSLWDISTH
LWTSLQT*SLASCST*ISLQ*LELVLELEPTSWR
DMLLTTRTLLKVLSSSTLIPMPRVGWIGQPTS*
QASPLPFRR*SLDIFSARKSSLEILS*YKSTEI
SLHMHPTWITLNCTGTATTTAET*TLSVEVISPS
GVL*CWW*ETKHLMKMQWWNVTQNWTPPRPRSS
RWLTPEVSPS*LSQAS*PRPSSTSCKAWATWPH
PA*LACPGLVQPL*PVQHPLMATGPALAPCPRAA
SLELFLRGPRGTPWRSPVEWPLLP*SGTQPSPP
PELTWEVLKGHWATVSKGKRADHAGR*P*SLIA
TLTLTFNP*FPPAPGRDVLISLRDPDP*ILLLPH
FDVKVERAYASSVLI*VSIAEG*EVVVVVLVPP
SDSPYLSHICKGRGFGAGAPFTKAEVASH*PFR
TLKGMDLRECVSGGDLLVG*WSSGCDRNIQCKKE
VGMGVGGQ*TSVGKDWCWGNRKGPGAVWLH*LW
*LSVHLEWDWGGS*AWAGLLGAWHRVERATLGL
*PHCSMCGGCPPVSHNFCYNNKL*RNLSTV

Frame 1

GLREARAGAGPSQRQVKVEAAAAAAGHHGGAAG
GADHRGEATVARTDA*GGQDSLCGDTIRLCHFH
CLWHPQTQTPSDPYLPRCGTQL*ILLPATVSVRG
HAGNHSELCAGSCGCPWNGRGSPCVPFGISVPI
SGPACRHDPLRPAVPKFLYNNWSWCWSWSLHPG
EICS*PPGHC*RSCPHQH*SQCQGLDGLGSPQAN
RPHLFHSGDDPWTSFQPGRALWKF*VDTKVQKY
HYTCTQPG*H*IVLEQLQQPPRPEL*AWR*YHP
QVSCDAGGRRPSTS*RCSGGM*LKTGPHPDLVPQ
DG*LRRSAPADSARQADRGLQVLPARHGLHGLI
LHDSPVPVSYSLSDQCSIR*WQPVPLSHPVPEQ
RVWNSFFGAPGAHHGGLLLNGPCCPRVGPSPHLP
QS*PGRC*RGIGPP*AREKGQIMRGDDLDL*LL
P*P*PLTRDSPQLLEEMS*YLLGTQTPKFSSSP
ILMLRWRGHMHPLS*SRCL*LRGKRLL*LSWCLH
QTLPTCPIFARGGDLGLGLHSPKLRWLLINPLG
L*RVWTYVNVCQGETCWWVSGPQDVIETSSVKR
KLEWELAGSERVWGRIGAGATGRGLGPFGCTNFG
SSVCI*SGTGEGAKLGLGCLGLGIGWKGLPWGS
DHTVVCVEGALPSPTTSAITINCRGI*VPL

Frame 2

VCGKPEPGRARVKGK*RWKRPRRQQATMAELQE
VQITEEKPLLPGQTPEAAKTHSVETPYGSVTFT
VYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFE
DMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPS
LDQLADMIPCVLQYLNFSTIIGVGVGAGAYILA
RYALNHPDTVEGLVLINIDPNAKGWMDWAAHKL
TGLTSSIPEMILGHLFSQEELSGNSELIQKYRNI
ITHAPNLDNIELYWNSYNNRRDLNFERGGDITL
RCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFL
KMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASS
CMTRLSRSRTASLTSAASVDGNRSRSRTLSQSS
ESGTLSSGPPGHTMEVSC*MALVALEWDPALTS
PRANLGGAEGALGHRKQGKKGRSCGEMTLIFDCY
PNLDL*PVIPPSSWKRCPNIS*GPRPLNSPPPP
F*C*GGEGICILCPDLGVYS*GVRGCCSCPGAS
IRLSLLVPYLQGEGIWGWGSIHQS*GGFSLTL*D
SEGYGPT*MCVRGRLAGGLVVLRM**KHPV*KG
SWNGSWRAVNECGEGLVLGQQEGAWGRLAALTL
VAQCASRVGLGRELSLGWAAWGLA*GGKGYPGAL
TTL*YVWRVPSRLPQLLL*Q*TVEESEYR

Sequence NM_201536

CGGCCCCCCGCATTCCCCGCCCCCACCTCCCCGCCTTGTTGTCCAACTTCTCCCGGAGCAGCCGGAGAGCAGGCGTCGGGACGCAGCAAAGAGAGGAGAG
GCCACCATGGCGGAGCTGCAGGAGGTGCAGATCACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGACTCACTCTGTGGAGACAC
CATACGGCTCTGTCACTTTCACTGTCTATGGCACCCCCAAACCCAAACGCCCAGCGATCCTTACCTACCACGATGTGGGACTCAACTATAAATCTTGCTT
CCAGCCACTGTTTCAGTTCGAGGACATGCAGGAAATCATTCAGAACTTTGTGCGGGTTCATGTGGATGCCCCTGGAATGGAAGAGGGAGCCCCTGTGTTC
CCTTTGGGATATCAGTACCCATCTCTGGACCAGCTTGCAGACATGATCCCTTGCGTCCTGCAGTACCTAAATTTCTCTACAATAATTGGAGTTGGTGTTG
GAGCTGGAGCCTACATCCTGGCGAGATATGCTCTTAACCACCCGGACACTGTTGAAGGTCTTGTCCTCATCAACATTGATCCCAATGCCAAGGGTTGGAT
GGATTGGGCAGCCCACAAGCTAACAGGCCTCACCTCTTCCATTCCGGAGATGATCCTTGGACATCTTTTCAGCCAGGAAGAGCTCTCTGGAAATTCTGAG
TTGATACAAAAGTACAGAAATATCATTACACATGCACCCAACCTGGATAACATTGAATTGTACTGGAACAGCTACAACAACCGCCGAGACCTGAACTTTG
AGCGTGGAGGTGATATCACCCTCAGGTGTCCTGTGATGCTGGTGGTAGGAGACCAAGCACCTCATGAAGATGCAGTGGTGGAATGTAACTCAAAACTGGA
CCCCACCCAGACCTCGTTCCTCAAGATGGCTGACTCCGGAGGTCAGCCCCAGCTGACTCAGCCAGGCAAGCTGACCGAGGCCTTCAAGTACTTCCTGCAA
GGCATGGGCTACATGGCCTCATCCTGCATGACTCGCCTGTCCCGGTCTCGTACAGCCTCTCTGACCAGTGCAGCATCCGTTGATGGCAACCGGTCCCGCT
CTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGGCACACCATGGAGGTCTCCTGTTGAATGGCCCTTGTTGCCCTAGA
GTGGGACCCAGCCCTCACCTCCCCCAGAGCTAACCTGGGAGGTGCTGAAGGGGCATTGGGCCACCGTAAGCAAGGGAAAAAGGGCAGATCATGCGGGGAG
ATGACCTTGATCTTTGATTGCTACCCTAACCTTGACCTTTAACCCGTGATTCCCCCCAGCTCCTGGAAGAGATGTCCTAATATCTCTTAGGGACCCAGAC
CCCTAAATTCTCCTCCTCCCCCATTTTGATGTTAAGGTGGAGAGGGCATATGCATCCTCTGTCCTGATCTAGGTGTCTATAGCTGAGGGGTAAGAGGTTG
TTGTAGTTGTCCTGGTGCCTCCATCAGACTCTCCCTACTTGTCCCATATTTGCAAGGGGAGGGGATTTGGGGCTGGGGCTCCATTCACCAAAGCTGAGGT
GGCTTCTCATTAACCCTTTAGGACTCTGAAGGGTATGGACCTACGTGAATGTGTGTCAGGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCAGGATGTGAT
AGAAACATCCAGTGTAAAAAGGAAGTTGGAATGGGAGTTGGCGGGCAGTGAACGAGTGTGGGGAAGGATTGGTGCTGGGGCAACAGGAAGGGGCCTGGGG
CCGTTTGGCTGCACTAACTTTGGTAGCTCAGTGTGCATCTAGAGTGGGACTGGGGAGGGAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTGGCATAGGGT
GGAAAGGGCTACCCTGGGGCTCTGACCACACTGTAGTATGTGTGGAGGGTGCCCTCCCGTCTCCCACAACTTCTGCTATAACAATAAACTGTAGAGGAAT
CTGAGTACCGTTA
  • refseq_NDRG2.F1 (forward primer)
  • refseq_NDRG2.R1 (reverse primer)
  • Single exon skipping

Frame 0

RPPAFPAPTSPPCCPTSPGAAGEQASGRSKERR
GHHGGAAGGADHRGEATVARTDA*GGQDSLCGDT
IRLCHFHCLWHPQTQTPSDPYLPRCGTQL*ILL
PATVSVRGHAGNHSELCAGSCGCPWNGRGSPCV
PFGISVPISGPACRHDPLRPAVPKFLYNNWSWCW
SWSLHPGEICS*PPGHC*RSCPHQH*SQCQGLD
GLGSPQANRPHLFHSGDDPWTSFQPGRALWKF*
VDTKVQKYHYTCTQPG*H*IVLEQLQQPPRPEL*
AWR*YHPQVSCDAGGRRPSTS*RCSGGM*LKTG
PHPDLVPQDG*LRRSAPADSARQADRGLQVLPA
RHGLHGLILHDSPVPVSYSLSDQCSIR*WQPVPL
SHPVPEQRVWNSFFGAPGAHHGGLLLNGPCCPR
VGPSPHLPQS*PGRC*RGIGPP*AREKGQIMRG
DDLDL*LLP*P*PLTRDSPQLLEEMS*YLLGTQT
PKFSSSPILMLRWRGHMHPLS*SRCL*LRGKRL
L*LSWCLHQTLPTCPIFARGGDLGLGLHSPKLR
WLLINPLGL*RVWTYVNVCQGETCWWVSGPQDVI
ETSSVKRKLEWELAGSERVWGRIGAGATGRGLG
PFGCTNFGSSVCI*SGTGEGAKLGLGCLGLGIG
WKGLPWGSDHTVVCVEGALPSPTTSAITINCRGI
*VPL

Frame 1

GPPHSPPPPPRLVVQLLPEQPESRRRDAAKRGE
ATMAELQEVQITEEKPLLPGQTPEAAKTHSVET
PYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCF
QPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVF
PLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGV
GAGAYILARYALNHPDTVEGLVLINIDPNAKGWM
DWAAHKLTGLTSSIPEMILGHLFSQEELSGNSE
LIQKYRNIITHAPNLDNIELYWNSYNNRRDLNF
ERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLD
PTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQ
GMGYMASSCMTRLSRSRTASLTSAASVDGNRSR
SRTLSQSSESGTLSSGPPGHTMEVSC*MALVALE
WDPALTSPRANLGGAEGALGHRKQGKKGRSCGE
MTLIFDCYPNLDL*PVIPPSSWKRCPNIS*GPR
PLNSPPPPF*C*GGEGICILCPDLGVYS*GVRGC
CSCPGASIRLSLLVPYLQGEGIWGWGSIHQS*G
GFSLTL*DSEGYGPT*MCVRGRLAGGLVVLRM*
*KHPV*KGSWNGSWRAVNECGEGLVLGQQEGAWG
RLAALTLVAQCASRVGLGRELSLGWAAWGLA*G
GKGYPGALTTL*YVWRVPSRLPQLLL*Q*TVEE
SEYR

Frame 2

APRIPRPHLPALLSNFSRSSRRAGVGTQQREER
PPWRSCRRCRSQRRSHCCQDRRLRRPRLTLWRH
HTALSLSLSMAPPNPNAQRSLPTTMWDSTINLA
SSHCFSSRTCRKSFRTLCGFMWMPLEWKREPLCS
LWDISTHLWTSLQT*SLASCST*ISLQ*LELVL
ELEPTSWRDMLLTTRTLLKVLSSSTLIPMPRVG
WIGQPTS*QASPLPFRR*SLDIFSARKSSLEILS
*YKSTEISLHMHPTWITLNCTGTATTTAET*TL
SVEVISPSGVL*CWW*ETKHLMKMQWWNVTQNW
TPPRPRSSRWLTPEVSPS*LSQAS*PRPSSTSCK
AWATWPHPA*LACPGLVQPL*PVQHPLMATGPA
LAPCPRAASLELFLRGPRGTPWRSPVEWPLLP*
SGTQPSPPPELTWEVLKGHWATVSKGKRADHAGR
*P*SLIATLTLTFNP*FPPAPGRDVLISLRDPD
P*ILLLPHFDVKVERAYASSVLI*VSIAEG*EV
VVVVLVPPSDSPYLSHICKGRGFGAGAPFTKAEV
ASH*PFRTLKGMDLRECVSGGDLLVG*WSSGCD
RNIQCKKEVGMGVGGQ*TSVGKDWCWGNRKGPG
AVWLH*LW*LSVHLEWDWGGS*AWAGLLGAWHRV
ERATLGL*PHCSMCGGCPPVSHNFCYNNKL*RN
LSTV

Sequence NM_201539

GGGTCTGCGGGAAGCCCGAGCCGGGGCGGGCCCGAGTCAAAGGCAAGTGAAGGTGGAAGCGGCCGCGGCGGCAGCAGGCCACCATGGCGGAGCTGCAGGA
GGTGCAGATCACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGGAGGCTGAGTTAGCTGCCCGAATCCTCCTGGACCAGGGACAG
ACTCACTCTGTGGAGACACCATACGGCTCTGTCACTTTCACTGTCTATGGCACCCCCAAACCCAAACGCCCAGCGATCCTTACCTACCACGATGTGGGAC
TCAACTATAAATCTTGCTTCCAGCCACTGTTTCAGTTCGAGGACATGCAGGAAATCATTCAGAACTTTGTGCGGGTTCATGTGGATGCCCCTGGAATGGA
AGAGGGAGCCCCTGTGTTCCCTTTGGGATATCAGTACCCATCTCTGGACCAGCTTGCAGACATGATCCCTTGCGTCCTGCAGTACCTAAATTTCTCTACA
ATAATTGGAGTTGGTGTTGGAGCTGGAGCCTACATCCTGGCGAGATATGCTCTTAACCACCCGGACACTGTTGAAGGTCTTGTCCTCATCAACATTGATC
CCAATGCCAAGGGTTGGATGGATTGGGCAGCCCACAAGCTAACAGGCCTCACCTCTTCCATTCCGGAGATGATCCTTGGACATCTTTTCAGCCAGGAAGA
GCTCTCTGGAAATTCTGAGTTGATACAAAAGTACAGAAATATCATTACACATGCACCCAACCTGGATAACATTGAATTGTACTGGAACAGCTACAACAAC
CGCCGAGACCTGAACTTTGAGCGTGGAGGTGATATCACCCTCAGGTGTCCTGTGATGCTGGTGGTAGGAGACCAAGCACCTCATGAAGATGCAGTGGTGG
AATGTAACTCAAAACTGGACCCCACCCAGACCTCGTTCCTCAAGATGGCTGACTCCGGAGGTCAGCCCCAGCTGACTCAGCCAGGCAAGCTGACCGAGGC
CTTCAAGTACTTCCTGCAAGGCATGGGCTACATGGCCTCATCCTGCATGACTCGCCTGTCCCGGTCTCGTACAGCCTCTCTGACCAGTGCAGCATCCGTT
GATGGCAACCGGTCCCGCTCTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGGCACACCATGGAGGTCTCCTGTTGAA
TGGCCCTTGTTGCCCTAGAGTGGGACCCAGCCCTCACCTCCCCCAGAGCTAACCTGGGAGGTGCTGAAGGGGCATTGGGCCACCGTAAGCAAGGGAAAAA
GGGCAGATCATGCGGGGAGATGACCTTGATCTTTGATTGCTACCCTAACCTTGACCTTTAACCCGTGATTCCCCCCAGCTCCTGGAAGAGATGTCCTAAT
ATCTCTTAGGGACCCAGACCCCTAAATTCTCCTCCTCCCCCATTTTGATGTTAAGGTGGAGAGGGCATATGCATCCTCTGTCCTGATCTAGGTGTCTATA
GCTGAGGGGTAAGAGGTTGTTGTAGTTGTCCTGGTGCCTCCATCAGACTCTCCCTACTTGTCCCATATTTGCAAGGGGAGGGGATTTGGGGCTGGGGCTC
CATTCACCAAAGCTGAGGTGGCTTCTCATTAACCCTTTAGGACTCTGAAGGGTATGGACCTACGTGAATGTGTGTCAGGGGGAGACTTGCTGGTGGGTTA
GTGGTCCTCAGGATGTGATAGAAACATCCAGTGTAAAAAGGAAGTTGGAATGGGAGTTGGCGGGCAGTGAACGAGTGTGGGGAAGGATTGGTGCTGGGGC
AACAGGAAGGGGCCTGGGGCCGTTTGGCTGCACTAACTTTGGTAGCTCAGTGTGCATCTAGAGTGGGACTGGGGAGGGAGCTAAGCTTGGGCTGGGCTGC
TTGGGGCTTGGCATAGGGTGGAAAGGGCTACCCTGGGGCTCTGACCACACTGTAGTATGTGTGGAGGGTGCCCTCCCGTCTCCCACAACTTCTGCTATAA
CAATAAACTGTAGAGGAATCTGAGTACCGTTA
  • refseq_NDRG2.F1 (forward primer)
  • refseq_NDRG2.R1 (reverse primer)
  • Single exon skipping

Frame 0

GSAGSPSRGGPESKASEGGSGRGGSRPPWRSCR
RCRSQRRSHCCQDRRLRRPRRLS*LPESSWTRDR
LTLWRHHTALSLSLSMAPPNPNAQRSLPTTMWD
STINLASSHCFSSRTCRKSFRTLCGFMWMPLEW
KREPLCSLWDISTHLWTSLQT*SLASCST*ISLQ
*LELVLELEPTSWRDMLLTTRTLLKVLSSSTLI
PMPRVGWIGQPTS*QASPLPFRR*SLDIFSARK
SSLEILS*YKSTEISLHMHPTWITLNCTGTATTT
AET*TLSVEVISPSGVL*CWW*ETKHLMKMQWW
NVTQNWTPPRPRSSRWLTPEVSPS*LSQAS*PR
PSSTSCKAWATWPHPA*LACPGLVQPL*PVQHPL
MATGPALAPCPRAASLELFLRGPRGTPWRSPVE
WPLLP*SGTQPSPPPELTWEVLKGHWATVSKGK
RADHAGR*P*SLIATLTLTFNP*FPPAPGRDVLI
SLRDPDP*ILLLPHFDVKVERAYASSVLI*VSI
AEG*EVVVVVLVPPSDSPYLSHICKGRGFGAGA
PFTKAEVASH*PFRTLKGMDLRECVSGGDLLVG*
WSSGCDRNIQCKKEVGMGVGGQ*TSVGKDWCWG
NRKGPGAVWLH*LW*LSVHLEWDWGGS*AWAGL
LGAWHRVERATLGL*PHCSMCGGCPPVSHNFCYN
NKL*RNLSTV

Frame 1

GLREARAGAGPSQRQVKVEAAAAAAGHHGGAAG
GADHRGEATVARTDA*GGQGG*VSCPNPPGPGT
DSLCGDTIRLCHFHCLWHPQTQTPSDPYLPRCGT
QL*ILLPATVSVRGHAGNHSELCAGSCGCPWNG
RGSPCVPFGISVPISGPACRHDPLRPAVPKFLY
NNWSWCWSWSLHPGEICS*PPGHC*RSCPHQH*S
QCQGLDGLGSPQANRPHLFHSGDDPWTSFQPGR
ALWKF*VDTKVQKYHYTCTQPG*H*IVLEQLQQ
PPRPEL*AWR*YHPQVSCDAGGRRPSTS*RCSGG
M*LKTGPHPDLVPQDG*LRRSAPADSARQADRG
LQVLPARHGLHGLILHDSPVPVSYSLSDQCSIR
*WQPVPLSHPVPEQRVWNSFFGAPGAHHGGLLLN
GPCCPRVGPSPHLPQS*PGRC*RGIGPP*AREK
GQIMRGDDLDL*LLP*P*PLTRDSPQLLEEMS*
YLLGTQTPKFSSSPILMLRWRGHMHPLS*SRCL*
LRGKRLL*LSWCLHQTLPTCPIFARGGDLGLGL
HSPKLRWLLINPLGL*RVWTYVNVCQGETCWWV
SGPQDVIETSSVKRKLEWELAGSERVWGRIGAGA
TGRGLGPFGCTNFGSSVCI*SGTGEGAKLGLGC
LGLGIGWKGLPWGSDHTVVCVEGALPSPTTSAI
TINCRGI*VPL

Frame 2

VCGKPEPGRARVKGK*RWKRPRRQQATMAELQE
VQITEEKPLLPGQTPEAAKEAELAARILLDQGQ
THSVETPYGSVTFTVYGTPKPKRPAILTYHDVG
LNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGME
EGAPVFPLGYQYPSLDQLADMIPCVLQYLNFST
IIGVGVGAGAYILARYALNHPDTVEGLVLINID
PNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEE
LSGNSELIQKYRNIITHAPNLDNIELYWNSYNN
RRDLNFERGGDITLRCPVMLVVGDQAPHEDAVV
ECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEA
FKYFLQGMGYMASSCMTRLSRSRTASLTSAASV
DGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC*
MALVALEWDPALTSPRANLGGAEGALGHRKQGKK
GRSCGEMTLIFDCYPNLDL*PVIPPSSWKRCPN
IS*GPRPLNSPPPPF*C*GGEGICILCPDLGVY
S*GVRGCCSCPGASIRLSLLVPYLQGEGIWGWGS
IHQS*GGFSLTL*DSEGYGPT*MCVRGRLAGGL
VVLRM**KHPV*KGSWNGSWRAVNECGEGLVLG
QQEGAWGRLAALTLVAQCASRVGLGRELSLGWAA
WGLA*GGKGYPGALTTL*YVWRVPSRLPQLLL*
Q*TVEESEYR

Sequence NM_201540

GGGTCTGCGGGAAGCCCGAGCCGGGGCGGGCCCGAGTCAAAGGCAAGTGAAGGTGGAAGCGGCCGCGGCGGCAGCAGACCCCAGAGTCAGAAGGAGTGAG
AACCCTGACCCCTAATCCCACTGCATCCAGCCAATAGGAGCCCAGCCACCATGGCGGAGCTGCAGGAGGTGCAGATCACAGAGGAGAAGCCACTGTTGCC
AGGACAGACGCCTGAGGCGGCCAAGGAGGCTGAGTTAGCTGCCCGAATCCTCCTGGACCAGGGACAGACTCACTCTGTGGAGACACCATACGGCTCTGTC
ACTTTCACTGTCTATGGCACCCCCAAACCCAAACGCCCAGCGATCCTTACCTACCACGATGTGGGACTCAACTATAAATCTTGCTTCCAGCCACTGTTTC
AGTTCGAGGACATGCAGGAAATCATTCAGAACTTTGTGCGGGTTCATGTGGATGCCCCTGGAATGGAAGAGGGAGCCCCTGTGTTCCCTTTGGGATATCA
GTACCCATCTCTGGACCAGCTTGCAGACATGATCCCTTGCGTCCTGCAGTACCTAAATTTCTCTACAATAATTGGAGTTGGTGTTGGAGCTGGAGCCTAC
ATCCTGGCGAGATATGCTCTTAACCACCCGGACACTGTTGAAGGTCTTGTCCTCATCAACATTGATCCCAATGCCAAGGGTTGGATGGATTGGGCAGCCC
ACAAGCTAACAGGCCTCACCTCTTCCATTCCGGAGATGATCCTTGGACATCTTTTCAGCCAGGAAGAGCTCTCTGGAAATTCTGAGTTGATACAAAAGTA
CAGAAATATCATTACACATGCACCCAACCTGGATAACATTGAATTGTACTGGAACAGCTACAACAACCGCCGAGACCTGAACTTTGAGCGTGGAGGTGAT
ATCACCCTCAGGTGTCCTGTGATGCTGGTGGTAGGAGACCAAGCACCTCATGAAGATGCAGTGGTGGAATGTAACTCAAAACTGGACCCCACCCAGACCT
CGTTCCTCAAGATGGCTGACTCCGGAGGTCAGCCCCAGCTGACTCAGCCAGGCAAGCTGACCGAGGCCTTCAAGTACTTCCTGCAAGGCATGGGCTACAT
GGCCTCATCCTGCATGACTCGCCTGTCCCGGTCTCGTACAGCCTCTCTGACCAGTGCAGCATCCGTTGATGGCAACCGGTCCCGCTCTCGCACCCTGTCC
CAGAGCAGCGAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGGCACACCATGGAGGTCTCCTGTTGAATGGCCCTTGTTGCCCTAGAGTGGGACCCAGCCC
TCACCTCCCCCAGAGCTAACCTGGGAGGTGCTGAAGGGGCATTGGGCCACCGTAAGCAAGGGAAAAAGGGCAGATCATGCGGGGAGATGACCTTGATCTT
TGATTGCTACCCTAACCTTGACCTTTAACCCGTGATTCCCCCCAGCTCCTGGAAGAGATGTCCTAATATCTCTTAGGGACCCAGACCCCTAAATTCTCCT
CCTCCCCCATTTTGATGTTAAGGTGGAGAGGGCATATGCATCCTCTGTCCTGATCTAGGTGTCTATAGCTGAGGGGTAAGAGGTTGTTGTAGTTGTCCTG
GTGCCTCCATCAGACTCTCCCTACTTGTCCCATATTTGCAAGGGGAGGGGATTTGGGGCTGGGGCTCCATTCACCAAAGCTGAGGTGGCTTCTCATTAAC
CCTTTAGGACTCTGAAGGGTATGGACCTACGTGAATGTGTGTCAGGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCAGGATGTGATAGAAACATCCAGTG
TAAAAAGGAAGTTGGAATGGGAGTTGGCGGGCAGTGAACGAGTGTGGGGAAGGATTGGTGCTGGGGCAACAGGAAGGGGCCTGGGGCCGTTTGGCTGCAC
TAACTTTGGTAGCTCAGTGTGCATCTAGAGTGGGACTGGGGAGGGAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTGGCATAGGGTGGAAAGGGCTACCC
TGGGGCTCTGACCACACTGTAGTATGTGTGGAGGGTGCCCTCCCGTCTCCCACAACTTCTGCTATAACAATAAACTGTAGAGGAATCTGAGTACCGTTA
  • refseq_NDRG2.F1 (forward primer)
  • refseq_NDRG2.R1 (reverse primer)
  • Single exon skipping

Frame 0

GSAGSPSRGGPESKASEGGSGRGGSRPQSQKE*
EP*PLIPLHPANRSPATMAELQEVQITEEKPLLP
GQTPEAAKEAELAARILLDQGQTHSVETPYGSV
TFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLF
QFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQ
YPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAY
ILARYALNHPDTVEGLVLINIDPNAKGWMDWAA
HKLTGLTSSIPEMILGHLFSQEELSGNSELIQKY
RNIITHAPNLDNIELYWNSYNNRRDLNFERGGD
ITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQT
SFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYM
ASSCMTRLSRSRTASLTSAASVDGNRSRSRTLS
QSSESGTLSSGPPGHTMEVSC*MALVALEWDPA
LTSPRANLGGAEGALGHRKQGKKGRSCGEMTLIF
DCYPNLDL*PVIPPSSWKRCPNIS*GPRPLNSP
PPPF*C*GGEGICILCPDLGVYS*GVRGCCSCP
GASIRLSLLVPYLQGEGIWGWGSIHQS*GGFSLT
L*DSEGYGPT*MCVRGRLAGGLVVLRM**KHPV
*KGSWNGSWRAVNECGEGLVLGQQEGAWGRLAA
LTLVAQCASRVGLGRELSLGWAAWGLA*GGKGYP
GALTTL*YVWRVPSRLPQLLL*Q*TVEESEYR

Frame 1

GLREARAGAGPSQRQVKVEAAAAAADPRVRRSE
NPDP*SHCIQPIGAQPPWRSCRRCRSQRRSHCC
QDRRLRRPRRLS*LPESSWTRDRLTLWRHHTALS
LSLSMAPPNPNAQRSLPTTMWDSTINLASSHCF
SSRTCRKSFRTLCGFMWMPLEWKREPLCSLWDI
STHLWTSLQT*SLASCST*ISLQ*LELVLELEPT
SWRDMLLTTRTLLKVLSSSTLIPMPRVGWIGQP
TS*QASPLPFRR*SLDIFSARKSSLEILS*YKS
TEISLHMHPTWITLNCTGTATTTAET*TLSVEVI
SPSGVL*CWW*ETKHLMKMQWWNVTQNWTPPRP
RSSRWLTPEVSPS*LSQAS*PRPSSTSCKAWAT
WPHPA*LACPGLVQPL*PVQHPLMATGPALAPCP
RAASLELFLRGPRGTPWRSPVEWPLLP*SGTQP
SPPPELTWEVLKGHWATVSKGKRADHAGR*P*S
LIATLTLTFNP*FPPAPGRDVLISLRDPDP*ILL
LPHFDVKVERAYASSVLI*VSIAEG*EVVVVVL
VPPSDSPYLSHICKGRGFGAGAPFTKAEVASH*
PFRTLKGMDLRECVSGGDLLVG*WSSGCDRNIQC
KKEVGMGVGGQ*TSVGKDWCWGNRKGPGAVWLH
*LW*LSVHLEWDWGGS*AWAGLLGAWHRVERAT
LGL*PHCSMCGGCPPVSHNFCYNNKL*RNLSTV

Frame 2

VCGKPEPGRARVKGK*RWKRPRRQQTPESEGVR
TLTPNPTASSQ*EPSHHGGAAGGADHRGEATVA
RTDA*GGQGG*VSCPNPPGPGTDSLCGDTIRLC
HFHCLWHPQTQTPSDPYLPRCGTQL*ILLPATVS
VRGHAGNHSELCAGSCGCPWNGRGSPCVPFGIS
VPISGPACRHDPLRPAVPKFLYNNWSWCWSWSL
HPGEICS*PPGHC*RSCPHQH*SQCQGLDGLGSP
QANRPHLFHSGDDPWTSFQPGRALWKF*VDTKV
QKYHYTCTQPG*H*IVLEQLQQPPRPEL*AWR*
YHPQVSCDAGGRRPSTS*RCSGGM*LKTGPHPDL
VPQDG*LRRSAPADSARQADRGLQVLPARHGLH
GLILHDSPVPVSYSLSDQCSIR*WQPVPLSHPV
PEQRVWNSFFGAPGAHHGGLLLNGPCCPRVGPSP
HLPQS*PGRC*RGIGPP*AREKGQIMRGDDLDL
*LLP*P*PLTRDSPQLLEEMS*YLLGTQTPKFS
SSPILMLRWRGHMHPLS*SRCL*LRGKRLL*LSW
CLHQTLPTCPIFARGGDLGLGLHSPKLRWLLIN
PLGL*RVWTYVNVCQGETCWWVSGPQDVIETSS
VKRKLEWELAGSERVWGRIGAGATGRGLGPFGCT
NFGSSVCI*SGTGEGAKLGLGCLGLGIGWKGLP
WGSDHTVVCVEGALPSPTTSAITINCRGI*VPL

Sequence NM_201535

CGGCCCCCCGCATTCCCCGCCCCCACCTCCCCGCCTTGTTGTCCAACTTCTCCCGGAGCAGCCGGAGAGCAGGCGTCGGGACGCAGCAAAGAGAGGAGAG
ACCCCAGAGTCAGAAGGAGTGAGAACCCTGACCCCTAATCCCACTGCATCCAGCCAATAGGAGCCCAGCCACCATGGCGGAGCTGCAGGAGGTGCAGATC
ACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGGAGGCTGAGTTAGCTGCCCGAATCCTCCTGGACCAGGGACAGACTCACTCTG
TGGAGACACCATACGGCTCTGTCACTTTCACTGTCTATGGCACCCCCAAACCCAAACGCCCAGCGATCCTTACCTACCACGATGTGGGACTCAACTATAA
ATCTTGCTTCCAGCCACTGTTTCAGTTCGAGGACATGCAGGAAATCATTCAGAACTTTGTGCGGGTTCATGTGGATGCCCCTGGAATGGAAGAGGGAGCC
CCTGTGTTCCCTTTGGGATATCAGTACCCATCTCTGGACCAGCTTGCAGACATGATCCCTTGCGTCCTGCAGTACCTAAATTTCTCTACAATAATTGGAG
TTGGTGTTGGAGCTGGAGCCTACATCCTGGCGAGATATGCTCTTAACCACCCGGACACTGTTGAAGGTCTTGTCCTCATCAACATTGATCCCAATGCCAA
GGGTTGGATGGATTGGGCAGCCCACAAGCTAACAGGCCTCACCTCTTCCATTCCGGAGATGATCCTTGGACATCTTTTCAGCCAGGAAGAGCTCTCTGGA
AATTCTGAGTTGATACAAAAGTACAGAAATATCATTACACATGCACCCAACCTGGATAACATTGAATTGTACTGGAACAGCTACAACAACCGCCGAGACC
TGAACTTTGAGCGTGGAGGTGATATCACCCTCAGGTGTCCTGTGATGCTGGTGGTAGGAGACCAAGCACCTCATGAAGATGCAGTGGTGGAATGTAACTC
AAAACTGGACCCCACCCAGACCTCGTTCCTCAAGATGGCTGACTCCGGAGGTCAGCCCCAGCTGACTCAGCCAGGCAAGCTGACCGAGGCCTTCAAGTAC
TTCCTGCAAGGCATGGGCTACATGGCCTCATCCTGCATGACTCGCCTGTCCCGGTCTCGTACAGCCTCTCTGACCAGTGCAGCATCCGTTGATGGCAACC
GGTCCCGCTCTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGGCACACCATGGAGGTCTCCTGTTGAATGGCCCTTGT
TGCCCTAGAGTGGGACCCAGCCCTCACCTCCCCCAGAGCTAACCTGGGAGGTGCTGAAGGGGCATTGGGCCACCGTAAGCAAGGGAAAAAGGGCAGATCA
TGCGGGGAGATGACCTTGATCTTTGATTGCTACCCTAACCTTGACCTTTAACCCGTGATTCCCCCCAGCTCCTGGAAGAGATGTCCTAATATCTCTTAGG
GACCCAGACCCCTAAATTCTCCTCCTCCCCCATTTTGATGTTAAGGTGGAGAGGGCATATGCATCCTCTGTCCTGATCTAGGTGTCTATAGCTGAGGGGT
AAGAGGTTGTTGTAGTTGTCCTGGTGCCTCCATCAGACTCTCCCTACTTGTCCCATATTTGCAAGGGGAGGGGATTTGGGGCTGGGGCTCCATTCACCAA
AGCTGAGGTGGCTTCTCATTAACCCTTTAGGACTCTGAAGGGTATGGACCTACGTGAATGTGTGTCAGGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCA
GGATGTGATAGAAACATCCAGTGTAAAAAGGAAGTTGGAATGGGAGTTGGCGGGCAGTGAACGAGTGTGGGGAAGGATTGGTGCTGGGGCAACAGGAAGG
GGCCTGGGGCCGTTTGGCTGCACTAACTTTGGTAGCTCAGTGTGCATCTAGAGTGGGACTGGGGAGGGAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTG
GCATAGGGTGGAAAGGGCTACCCTGGGGCTCTGACCACACTGTAGTATGTGTGGAGGGTGCCCTCCCGTCTCCCACAACTTCTGCTATAACAATAAACTG
TAGAGGAATCTGAGTACCGTTA
  • refseq_NDRG2.F1 (forward primer)
  • refseq_NDRG2.R1 (reverse primer)
  • Single exon skipping

Frame 0

RPPAFPAPTSPPCCPTSPGAAGEQASGRSKERR
DPRVRRSENPDP*SHCIQPIGAQPPWRSCRRCRS
QRRSHCCQDRRLRRPRRLS*LPESSWTRDRLTL
WRHHTALSLSLSMAPPNPNAQRSLPTTMWDSTI
NLASSHCFSSRTCRKSFRTLCGFMWMPLEWKREP
LCSLWDISTHLWTSLQT*SLASCST*ISLQ*LE
LVLELEPTSWRDMLLTTRTLLKVLSSSTLIPMP
RVGWIGQPTS*QASPLPFRR*SLDIFSARKSSLE
ILS*YKSTEISLHMHPTWITLNCTGTATTTAET
*TLSVEVISPSGVL*CWW*ETKHLMKMQWWNVT
QNWTPPRPRSSRWLTPEVSPS*LSQAS*PRPSST
SCKAWATWPHPA*LACPGLVQPL*PVQHPLMAT
GPALAPCPRAASLELFLRGPRGTPWRSPVEWPL
LP*SGTQPSPPPELTWEVLKGHWATVSKGKRADH
AGR*P*SLIATLTLTFNP*FPPAPGRDVLISLR
DPDP*ILLLPHFDVKVERAYASSVLI*VSIAEG
*EVVVVVLVPPSDSPYLSHICKGRGFGAGAPFTK
AEVASH*PFRTLKGMDLRECVSGGDLLVG*WSS
GCDRNIQCKKEVGMGVGGQ*TSVGKDWCWGNRK
GPGAVWLH*LW*LSVHLEWDWGGS*AWAGLLGAW
HRVERATLGL*PHCSMCGGCPPVSHNFCYNNKL
*RNLSTV

Frame 1

GPPHSPPPPPRLVVQLLPEQPESRRRDAAKRGE
TPESEGVRTLTPNPTASSQ*EPSHHGGAAGGAD
HRGEATVARTDA*GGQGG*VSCPNPPGPGTDSLC
GDTIRLCHFHCLWHPQTQTPSDPYLPRCGTQL*
ILLPATVSVRGHAGNHSELCAGSCGCPWNGRGS
PCVPFGISVPISGPACRHDPLRPAVPKFLYNNWS
WCWSWSLHPGEICS*PPGHC*RSCPHQH*SQCQ
GLDGLGSPQANRPHLFHSGDDPWTSFQPGRALW
KF*VDTKVQKYHYTCTQPG*H*IVLEQLQQPPRP
EL*AWR*YHPQVSCDAGGRRPSTS*RCSGGM*L
KTGPHPDLVPQDG*LRRSAPADSARQADRGLQV
LPARHGLHGLILHDSPVPVSYSLSDQCSIR*WQP
VPLSHPVPEQRVWNSFFGAPGAHHGGLLLNGPC
CPRVGPSPHLPQS*PGRC*RGIGPP*AREKGQI
MRGDDLDL*LLP*P*PLTRDSPQLLEEMS*YLLG
TQTPKFSSSPILMLRWRGHMHPLS*SRCL*LRG
KRLL*LSWCLHQTLPTCPIFARGGDLGLGLHSP
KLRWLLINPLGL*RVWTYVNVCQGETCWWVSGPQ
DVIETSSVKRKLEWELAGSERVWGRIGAGATGR
GLGPFGCTNFGSSVCI*SGTGEGAKLGLGCLGL
GIGWKGLPWGSDHTVVCVEGALPSPTTSAITINC
RGI*VPL

Frame 2

APRIPRPHLPALLSNFSRSSRRAGVGTQQREER
PQSQKE*EP*PLIPLHPANRSPATMAELQEVQI
TEEKPLLPGQTPEAAKEAELAARILLDQGQTHS
VETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYK
SCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGA
PVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIG
VGVGAGAYILARYALNHPDTVEGLVLINIDPNAK
GWMDWAAHKLTGLTSSIPEMILGHLFSQEELSG
NSELIQKYRNIITHAPNLDNIELYWNSYNNRRD
LNFERGGDITLRCPVMLVVGDQAPHEDAVVECNS
KLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKY
FLQGMGYMASSCMTRLSRSRTASLTSAASVDGN
RSRSRTLSQSSESGTLSSGPPGHTMEVSC*MALV
ALEWDPALTSPRANLGGAEGALGHRKQGKKGRS
CGEMTLIFDCYPNLDL*PVIPPSSWKRCPNIS*
GPRPLNSPPPPF*C*GGEGICILCPDLGVYS*GV
RGCCSCPGASIRLSLLVPYLQGEGIWGWGSIHQ
S*GGFSLTL*DSEGYGPT*MCVRGRLAGGLVVL
RM**KHPV*KGSWNGSWRAVNECGEGLVLGQQEG
AWGRLAALTLVAQCASRVGLGRELSLGWAAWGL
A*GGKGYPGALTTL*YVWRVPSRLPQLLL*Q*T
VEESEYR

Sequence NM_201537

CGGCCCCCCGCATTCCCCGCCCCCACCTCCCCGCCTTGTTGTCCAACTTCTCCCGGAGCAGCCGGAGAGCAGGCGTCGGGACGCAGCAAAGAGAGGAGAG
GCCACCATGGCGGAGCTGCAGGAGGTGCAGATCACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGGAGGCTGAGTTAGCTGCCC
GAATCCTCCTGGACCAGGGACAGACTCACTCTGTGGAGACACCATACGGCTCTGTCACTTTCACTGTCTATGGCACCCCCAAACCCAAACGCCCAGCGAT
CCTTACCTACCACGATGTGGGACTCAACTATAAATCTTGCTTCCAGCCACTGTTTCAGTTCGAGGACATGCAGGAAATCATTCAGAACTTTGTGCGGGTT
CATGTGGATGCCCCTGGAATGGAAGAGGGAGCCCCTGTGTTCCCTTTGGGATATCAGTACCCATCTCTGGACCAGCTTGCAGACATGATCCCTTGCGTCC
TGCAGTACCTAAATTTCTCTACAATAATTGGAGTTGGTGTTGGAGCTGGAGCCTACATCCTGGCGAGATATGCTCTTAACCACCCGGACACTGTTGAAGG
TCTTGTCCTCATCAACATTGATCCCAATGCCAAGGGTTGGATGGATTGGGCAGCCCACAAGCTAACAGGCCTCACCTCTTCCATTCCGGAGATGATCCTT
GGACATCTTTTCAGCCAGGAAGAGCTCTCTGGAAATTCTGAGTTGATACAAAAGTACAGAAATATCATTACACATGCACCCAACCTGGATAACATTGAAT
TGTACTGGAACAGCTACAACAACCGCCGAGACCTGAACTTTGAGCGTGGAGGTGATATCACCCTCAGGTGTCCTGTGATGCTGGTGGTAGGAGACCAAGC
ACCTCATGAAGATGCAGTGGTGGAATGTAACTCAAAACTGGACCCCACCCAGACCTCGTTCCTCAAGATGGCTGACTCCGGAGGTCAGCCCCAGCTGACT
CAGCCAGGCAAGCTGACCGAGGCCTTCAAGTACTTCCTGCAAGGCATGGGCTACATGGCCTCATCCTGCATGACTCGCCTGTCCCGGTCTCGTACAGCCT
CTCTGACCAGTGCAGCATCCGTTGATGGCAACCGGTCCCGCTCTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGGCA
CACCATGGAGGTCTCCTGTTGAATGGCCCTTGTTGCCCTAGAGTGGGACCCAGCCCTCACCTCCCCCAGAGCTAACCTGGGAGGTGCTGAAGGGGCATTG
GGCCACCGTAAGCAAGGGAAAAAGGGCAGATCATGCGGGGAGATGACCTTGATCTTTGATTGCTACCCTAACCTTGACCTTTAACCCGTGATTCCCCCCA
GCTCCTGGAAGAGATGTCCTAATATCTCTTAGGGACCCAGACCCCTAAATTCTCCTCCTCCCCCATTTTGATGTTAAGGTGGAGAGGGCATATGCATCCT
CTGTCCTGATCTAGGTGTCTATAGCTGAGGGGTAAGAGGTTGTTGTAGTTGTCCTGGTGCCTCCATCAGACTCTCCCTACTTGTCCCATATTTGCAAGGG
GAGGGGATTTGGGGCTGGGGCTCCATTCACCAAAGCTGAGGTGGCTTCTCATTAACCCTTTAGGACTCTGAAGGGTATGGACCTACGTGAATGTGTGTCA
GGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCAGGATGTGATAGAAACATCCAGTGTAAAAAGGAAGTTGGAATGGGAGTTGGCGGGCAGTGAACGAGTG
TGGGGAAGGATTGGTGCTGGGGCAACAGGAAGGGGCCTGGGGCCGTTTGGCTGCACTAACTTTGGTAGCTCAGTGTGCATCTAGAGTGGGACTGGGGAGG
GAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTGGCATAGGGTGGAAAGGGCTACCCTGGGGCTCTGACCACACTGTAGTATGTGTGGAGGGTGCCCTCCC
GTCTCCCACAACTTCTGCTATAACAATAAACTGTAGAGGAATCTGAGTACCGTTA
  • refseq_NDRG2.F1 (forward primer)
  • refseq_NDRG2.R1 (reverse primer)
  • Single exon skipping

Frame 0

RPPAFPAPTSPPCCPTSPGAAGEQASGRSKERR
GHHGGAAGGADHRGEATVARTDA*GGQGG*VSCP
NPPGPGTDSLCGDTIRLCHFHCLWHPQTQTPSD
PYLPRCGTQL*ILLPATVSVRGHAGNHSELCAG
SCGCPWNGRGSPCVPFGISVPISGPACRHDPLRP
AVPKFLYNNWSWCWSWSLHPGEICS*PPGHC*R
SCPHQH*SQCQGLDGLGSPQANRPHLFHSGDDP
WTSFQPGRALWKF*VDTKVQKYHYTCTQPG*H*I
VLEQLQQPPRPEL*AWR*YHPQVSCDAGGRRPS
TS*RCSGGM*LKTGPHPDLVPQDG*LRRSAPAD
SARQADRGLQVLPARHGLHGLILHDSPVPVSYSL
SDQCSIR*WQPVPLSHPVPEQRVWNSFFGAPGA
HHGGLLLNGPCCPRVGPSPHLPQS*PGRC*RGI
GPP*AREKGQIMRGDDLDL*LLP*P*PLTRDSPQ
LLEEMS*YLLGTQTPKFSSSPILMLRWRGHMHP
LS*SRCL*LRGKRLL*LSWCLHQTLPTCPIFAR
GGDLGLGLHSPKLRWLLINPLGL*RVWTYVNVCQ
GETCWWVSGPQDVIETSSVKRKLEWELAGSERV
WGRIGAGATGRGLGPFGCTNFGSSVCI*SGTGE
GAKLGLGCLGLGIGWKGLPWGSDHTVVCVEGALP
SPTTSAITINCRGI*VPL

Frame 1

GPPHSPPPPPRLVVQLLPEQPESRRRDAAKRGE
ATMAELQEVQITEEKPLLPGQTPEAAKEAELAA
RILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAI
LTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRV
HVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCV
LQYLNFSTIIGVGVGAGAYILARYALNHPDTVEG
LVLINIDPNAKGWMDWAAHKLTGLTSSIPEMIL
GHLFSQEELSGNSELIQKYRNIITHAPNLDNIE
LYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQA
PHEDAVVECNSKLDPTQTSFLKMADSGGQPQLT
QPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTA
SLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGH
TMEVSC*MALVALEWDPALTSPRANLGGAEGAL
GHRKQGKKGRSCGEMTLIFDCYPNLDL*PVIPP
SSWKRCPNIS*GPRPLNSPPPPF*C*GGEGICIL
CPDLGVYS*GVRGCCSCPGASIRLSLLVPYLQG
EGIWGWGSIHQS*GGFSLTL*DSEGYGPT*MCV
RGRLAGGLVVLRM**KHPV*KGSWNGSWRAVNEC
GEGLVLGQQEGAWGRLAALTLVAQCASRVGLGR
ELSLGWAAWGLA*GGKGYPGALTTL*YVWRVPS
RLPQLLL*Q*TVEESEYR

Frame 2

APRIPRPHLPALLSNFSRSSRRAGVGTQQREER
PPWRSCRRCRSQRRSHCCQDRRLRRPRRLS*LP
ESSWTRDRLTLWRHHTALSLSLSMAPPNPNAQR
SLPTTMWDSTINLASSHCFSSRTCRKSFRTLCGF
MWMPLEWKREPLCSLWDISTHLWTSLQT*SLAS
CST*ISLQ*LELVLELEPTSWRDMLLTTRTLLK
VLSSSTLIPMPRVGWIGQPTS*QASPLPFRR*SL
DIFSARKSSLEILS*YKSTEISLHMHPTWITLN
CTGTATTTAET*TLSVEVISPSGVL*CWW*ETK
HLMKMQWWNVTQNWTPPRPRSSRWLTPEVSPS*L
SQAS*PRPSSTSCKAWATWPHPA*LACPGLVQP
L*PVQHPLMATGPALAPCPRAASLELFLRGPRG
TPWRSPVEWPLLP*SGTQPSPPPELTWEVLKGHW
ATVSKGKRADHAGR*P*SLIATLTLTFNP*FPP
APGRDVLISLRDPDP*ILLLPHFDVKVERAYAS
SVLI*VSIAEG*EVVVVVLVPPSDSPYLSHICKG
RGFGAGAPFTKAEVASH*PFRTLKGMDLRECVS
GGDLLVG*WSSGCDRNIQCKKEVGMGVGGQ*TS
VGKDWCWGNRKGPGAVWLH*LW*LSVHLEWDWGG
S*AWAGLLGAWHRVERATLGL*PHCSMCGGCPP
VSHNFCYNNKL*RNLSTV

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