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Sequences

Sequence NM_031488

GGCAGGCCAATATGGCTTCCTGCACCTGGTGACGCTTGGCGAAACTGAGGTCTCATGGAGAAGCCCCGGAGTATTGAGGAGACCCCATCTTCAGAACCAA
TGGAGGAAGAGGAAGATGACGACTTGGAGCTGTTTGGTGGCTATGATAGTTTCCGGAGTTATAACAGCAGTGTGGGCAGTGAGAGCAGCTCCTATCTGGA
GGAGTCAAGTGAAGCAGAAAATGAGGATCGGGAAGCAGGGGAACTGCCGACCTCCCCGCTGCATTTGCTCAGCCCTGGGACTCCTCGCTCCTTGGATGGC
AGTGGTTCTGAGCCAGCTGTCTGTGAGATGTGTGGTATCGTGGGTACAAGGGAAGCCTTCTTCTCCAAGACCAAGAGGTTCTGCAGCGTCTCCTGCTCCA
GGAGCTACTCCTCCAACTCCAAGAAAGCCAGTATCTTGGCTAGGTTACAGGGAAAACCACCGACCAAAAAAGCCAAAGTCCTGCACAAGGCTGCCTGGTC
TGCCAAAATTGGAGCCTTCCTCCACTCTCAAGGGACAGGACAGCTGGCAGATGGGACACCAACAGGACAAGACGCTCTGGTCTTGGGCTTCGACTGGGGG
AAGTTCCTGAAGGATCACAGTTACAAGGCTGCTCCCGTCAGCTGTTTCAAGCACGTCCCACTCTATGACCAGTGGGAGGATGTGATGAAAGGGATGAAGG
TGGAGGTGCTCAACAGTGATGCTGTGCTCCCCAGCCGGGTGTACTGGATCGCCTCTGTCATCCAGACAGCAGGGTATCGGGTGCTGCTTCGGTATGAAGG
CTTTGAAAATGACGCCAGCCATGACTTCTGGTGCAACCTGGGAACAGTGGATGTCCACCCCATTGGCTGGTGTGCCATCAACAGCAAGATCCTAGTGCCC
CCACGGACCATCCATGCCAAGTTCACCGACTGGAAGGGCTACCTCATGAAACGGCTGGTGGGCTCCAGGACGCTTCCCGTGGATTTCCACATCAAGATGG
TGGAGAGCATGAAGTACCCCTTTAGGCAGGGCATGCGGCTGGAAGTGGTGGACAAGTCCCAGGTGTCACGCACTCGCATGGCTGTGGTGGACACAGTAAT
CGGGGGTCGCCTACGGCTCCTCTACGAGGATGGTGACAGTGACGACGACTTCTGGTGCCACATGTGGAGCCCCCTGATCCACCCAGTGGGTTGGTCACGA
CGTGTGGGCCACGGCATCAAGATGTCAGAGAGGCGAAGTGACATGGCCCATCACCCCACCTTCCGGAAGATCTACTGTGATGCCGTTCCTTACCTCTTCA
AGAAGGTACGAGCAGTCTACACAGAAGGCGGTTGGTTTGAGGAAGGGATGAAGCTGGAGGCCATTGACCCCCTGAATCTGGGCAACATCTGCGTGGCAAC
TGTCTGTAAGGTTCTCCTGGATGGATACCTGATGATCTGTGTGGACGGGGGGCCCTCCACAGATGGCTTGGACTGGTTCTGCTACCATGCCTCTTCCCAC
GCCATCTTCCCGGCCACCTTCTGTCAGAAGAATGACATTGAGCTCACACCGCCAAAAGGTTATGAGGCACAGACTTTCAACTGGGAGAACTACTTGGAGA
AGACCAAGTCGAAAGCCGCTCCATCGAGACTCTTTAACATGGATTGCCCAAACCATGGCTTCAAGGTGGGCATGAAGCTGGAGGCCGTGGACCTGATGGA
GCCCCGGCTCATCTGTGTGGCCACGGTGAAACGAGTGGTGCATCGGCTCCTCAGCATCCACTTTGACGGCTGGGACAGCGAGTACGACCAGTGGGTGGAC
TGCGAGTC
CCCAGACATCTACCCCGTCGGCTGGTGTGAGCTCACCGGCTACCAGCTCCAGCCTCCTGTGGCCGCAGAACCGGCCACACCGCTGAAGGCCA
AAGAGGCCACAAAGAAGAAAAAGAAACAGTTTGGGAAGAAAAGGAAAAGAATCCCGCCCACTAAGACGCGACCCCTCAGACAGGGGTCCAAGAAGCCCCT
GCTGGAGGACGACCCTCAGGGTGCCAGGAAGATCTCGTCGGAGCCTGTTCCTGGCGAGATCATTGCTGTGCGTGTGAAGGAAGAGCATCTAGACGTGGCC
TCGCCCGACAAGGCTTCAAGTCCAGAGCTGCCTGTCTCCGTCGAGAACATCAAGCAGGAAACAGACGACTGAGCCTTCCTGCCTCCAGCCTGGCTTCTAG
CTGGAAGCCAGCCCAGCGTTTCTCTACCACCACCACCATGCCTCCACCTGACTTTGGCTTGGAGACTGATCCTCTCTGTGTAAATTCTGCCCGGTGCTGT
GAAGGCTGGACGGTGGAGGACCTGCTGGGGTCTCCTGGGACCCGCCTGTTGCTTCTGCCCTCCCCTGTGGAAAGGTCTATATGACGGGCCGCCTGAGGCC
CCAGAACTCGTCTGTGAACCACCTTTTCCAGCCAGAGTTCCCAAAGCTGGAACGCTAGCTGCCTGCTCTTCCTTAAGATGGCCTCCCCCCGACCCGCCAC
GGCCCTCAGTTGCCAGGGATGGGGCCACCACTGTCACACTGTGGAATACAAGACAGTGAACTCTGTCTGCCTGAACGAGCCATGTAAATTAAGTTCTAGA
GCAGCTCTCTGAGCAGGATAAGGTCCCCTGACAGTGAGTTGTGTGGTGGGGGCAGCCTCTGCCTCAAAAATTCACCAAGCAGAATGCCTCTCAGCCTCAT
GTGTTGGTCCTCTGCTCCTCCTAGCTCCCCAGGGATGTTGGGGACCCAGCTTGTCTCGGCAGCTAAGAAGCAGTGACCAGGATGTGGATTTTGGCGACCT
GTGTGGTGGCCTTGAGCTGCTTTCTGTGTTTGTGAGGACTGACTCCCATTTCCTAAAGGAAATGCCCCCGGGGAGGACATTGGGAGGAAGATGGCCTGAG
TGTGCACTTTGGCTCTGCTACCTGCTCCTGAAGCCCCGCTAAAAATAATTCATCCAAGATTCCTTTGTAGTTAAAGGGTCCAGTTCTGACTGGAGCCTCT
AGAGAGCTGGGCTTGTATGTTCTTTTGGCCTTTTGTTCCTACCTAAATGAAGAAACCATGCCTGGAGGGGCCGTGAACACAGAACCCTCAAGACAAGGAT
GACAGAGCTGGAGGACACATCTAGCTGCCATTGCAACCTCACTGGGCTCCCCAGACTCTGTGTGTGAGAAATTAAACCCCCTGCTTGCTTGA
  • refseq_L3MBTL2.F2 (forward primer)
  • refseq_L3MBTL2.R2 (reverse primer)
  • Single exon skipping

Frame 0

GRPIWLPAPGDAWRN*GLMEKPRSIEETPSSEP
MEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLE
ESSEAENEDREAGELPTSPLHLLSPGTPRSLDG
SGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCS
RSYSSNSKKASILARLQGKPPTKKAKVLHKAAWS
AKIGAFLHSQGTGQLADGTPTGQDALVLGFDWG
KFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMK
VEVLNSDAVLPSRVYWIASVIQTAGYRVLLRYEG
FENDASHDFWCNLGTVDVHPIGWCAINSKILVP
PRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKM
VESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVI
GGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSR
RVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLF
KKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVAT
VCKVLLDGYLMICVDGGPSTDGLDWFCYHASSH
AIFPATFCQKNDIELTPPKGYEAQTFNWENYLE
KTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLME
PRLICVATVKRVVHRLLSIHFDGWDSEYDQWVD
CES
PDIYPVGWCELTGYQLQPPVAAEPATPLKA
KEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPL
LEDDPQGARKISSEPVPGEIIAVRVKEEHLDVA
SPDKASSPELPVSVENIKQETDD*AFLPPAWLL
AGSQPSVSLPPPPCLHLTLAWRLILSV*ILPGAV
KAGRWRTCWGLLGPACCFCPPLWKGLYDGPPEA
PELVCEPPFPARVPKAGTLAACSSLRWPPPDPP
RPSVARDGATTVTLWNTRQ*TLSA*TSHVN*VLE
QLSEQDKVP*Q*VVWWGQPLPQKFTKQNASQPH
VLVLCSS*LPRDVGDPACLGS*EAVTRMWILAT
CVVALSCFLCL*GLTPIS*RKCPRGGHWEEDGLS
VHFGSATCS*SPAKNNSSKIPL*LKGPVLTGAS
RELGLYVLLAFCSYLNEETMPGGAVNTEPSRQG
*QSWRTHLAAIATSLGSPDSVCEKLNPLLA*

Frame 1

AGQYGFLHLVTLGETEVSWRSPGVLRRPHLQNQ
WRKRKMTTWSCLVAMIVSGVITAVWAVRAAPIW
RSQVKQKMRIGKQGNCRPPRCICSALGLLAPWMA
VVLSQLSVRCVVSWVQGKPSSPRPRGSAASPAP
GATPPTPRKPVSWLGYRENHRPKKPKSCTRLPG
LPKLEPSSTLKGQDSWQMGHQQDKTLWSWASTGG
SS*RITVTRLLPSAVSSTSHSMTSGRM**KG*R
WRCSTVMLCSPAGCTGSPLSSRQQGIGCCFGMK
ALKMTPAMTSGATWEQWMSTPLAGVPSTARS*CP
HGPSMPSSPTGRATS*NGWWAPGRFPWISTSRW
WRA*STPLGRACGWKWWTSPRCHALAWLWWTQ*
SGVAYGSSTRMVTVTTTSGATCGAP*STQWVGHD
VWATASRCQRGEVTWPITPPSGRSTVMPFLTSS
RRYEQSTQKAVGLRKG*SWRPLTP*IWATSAWQ
LSVRFSWMDT**SVWTGGPPQMAWTGSATMPLPT
PSSRPPSVRRMTLSSHRQKVMRHRLSTGRTTWR
RPSRKPLHRDSLTWIAQTMASRWA*SWRPWT*W
SPGSSVWPR*NEWCIGSSASTLTAGTASTTSGWT
AS
PQTSTPSAGVSSPATSSSLLWPQNRPHR*RP
KRPQRRKRNSLGRKGKESRPLRRDPSDRGPRSP
CWRTTLRVPGRSRRSLFLARSLLCV*RKSI*TWP
RPTRLQVQSCLSPSRTSSRKQTTEPSCLQPGF*
LEASPAFLYHHHHAST*LWLGD*SSLCKFCPVL
*RLDGGGPAGVSWDPPVASALPCGKVYMTGRLRP
QNSSVNHLFQPEFPKLER*LPALP*DGLPPTRH
GPQLPGMGPPLSHCGIQDSELCLPERAM*IKF*
SSSLSRIRSPDSELCGGGSLCLKNSPSRMPLSLM
CWSSAPPSSPGMLGTQLVSAAKKQ*PGCGFWRP
VWWP*AAFCVCED*LPFPKGNAPGEDIGRKMA*
VCTLALLPAPEAPLKIIHPRFLCS*RVQF*LEPL
ESWACMFFWPFVPT*MKKPCLEGP*TQNPQDKD
DRAGGHI*LPLQPHWAPQTLCVRN*TPCLL

Frame 2

QANMASCTW*RLAKLRSHGEAPEY*GDPIFRTN
GGRGR*RLGAVWWL**FPEL*QQCGQ*EQLLSG
GVK*SRK*GSGSRGTADLPAAFAQPWDSSLLGW
QWF*ASCL*DVWYRGYKGSLLLQDQEVLQRLLLQ
ELLLQLQESQYLG*VTGKTTDQKSQSPAQGCLV
CQNWSLPPLSRDRTAGRWDTNRTRRSGLGLRLG
EVPEGSQLQGCSRQLFQARPTL*PVGGCDERDEG
GGAQQ*CCAPQPGVLDRLCHPDSRVSGAASV*R
L*K*RQP*LLVQPGNSGCPPHWLVCHQQQDPSA
PTDHPCQVHRLEGLPHETAGGLQDASRGFPHQDG
GEHEVPL*AGHAAGSGGQVPGVTHSHGCGGHSN
RGSPTAPLRGW*Q*RRLLVPHVEPPDPPSGLVT
TCGPRHQDVREAK*HGPSPHLPEDLL*CRSLPLQ
EGTSSLHRRRLV*GRDEAGGH*PPESGQHLRGN
CL*GSPGWIPDDLCGRGALHRWLGLVLLPCLFP
RHLPGHLLSEE*H*AHTAKRL*GTDFQLGELLGE
DQVESRSIETL*HGLPKPWLQGGHEAGGRGPDG
APAHLCGHGETSGASAPQHPL*RLGQRVRPVGG
LRV
PRHLPRRLV*AHRLPAPASCGRRTGHTAEGQ
RGHKEEKETVWEEKEKNPAH*DATPQTGVQEAP
AGGRPSGCQEDLVGACSWRDHCCACEGRASRRG
LARQGFKSRAACLRREHQAGNRRLSLPASSLASS
WKPAQRFSTTTTMPPPDFGLETDPLCVNSARCC
EGWTVEDLLGSPGTRLLLLPSPVERSI*RAA*G
PRTRL*TTFSSQSSQSWNASCLLFLKMASPRPAT
ALSCQGWGHHCHTVEYKTVNSVCLNEPCKLSSR
AAL*AG*GPLTVSCVVGAASASKIHQAECLSAS
CVGPLLLLAPQGCWGPSLSRQLRSSDQDVDFGDL
CGGLELLSVFVRTDSHFLKEMPPGRTLGGRWPE
CALWLCYLLLKPR*K*FIQDSFVVKGSSSDWSL
*RAGLVCSFGLLFLPK*RNHAWRGREHRTLKTRM
TELEDTSSCHCNLTGLPRLCV*EIKPPACL

Sequence NM_001003689

GGCAGGCCAATATGGCTTCCTGCACCTGGTGACGCTTGGCGAAACTGAGGTCTCATGGAGAAGCCCCGGAGTATTGAGGAGACCCCATCTTCAGAACCAA
TGGAGGAAGAGGAAGATGACGACTTGGAGCTGTTTGGTGGCTATGATAGTTTCCGGAGTTATAACAGCAGTGTGGGCAGTGAGAGCAGCTCCTATCTGGA
GGAGTCAAGTGAAGCAGAAAATGAGGATCGGGAAGCAGGGGAACTGCCGACCTCCCCGCTGCATTTGCTCAGCCCTGGGACTCCTCGCTCCTTGGATGGC
AGTGGTTCTGAGCCAGCTGTCTGTGAGATGTGTGGTATCGTGGGTACAAGGGAAGCCTTCTTCTCCAAGACCAAGAGGTTCTGCAGCGTCTCCTGCTCCA
GGAGCTACTCCTCCAACTCCAAGAAAGCCAGTATCTTGGCTAGGTTACAGGGAAAACCACCGACCAAAAAAGCCAAAGTCCTGCACAAGGCTGCCTGGTC
TGCCAAAATTGGAGCCTTCCTCCACTCTCAAGGGACAGGACAGCTGGCAGATGGGACACCAACAGGACAAGACGCTCTGGTCTTGGGCTTCGACTGGGGG
AAGTTCCTGAAGGATCACAGTTACAAGGCTGCTCCCGTCAGCTGTTTCAAGCACGTCCCACTCTATGACCAGTGGGAGGATGTGATGAAAGGGATGAAGG
TGGAGGTGCTCAACAGTGATGCTGTGCTCCCCAGCCGGGTGTACTGGATCGCCTCTGTCATCCAGACAGCAGGGTATCGGGTGCTGCTTCGGTATGAAGG
CTTTGAAAATGACGCCAGCCATGACTTCTGGTGCAACCTGGGAACAGTGGATGTCCACCCCATTGGCTGGTGTGCCATCAACAGCAAGATCCTAGTGCCC
CCACGGACCATCCATGCCAAGTTCACCGACTGGAAGGGCTACCTCATGAAACGGCTGGTGGGCTCCAGGACGCTTCCCGTGGATTTCCACATCAAGATGG
TGGAGAGCATGAAGTACCCCTTTAGGCAGGGCATGCGGCTGGAAGTGGTGGACAAGTCCCAGGTGTCACGCACTCGCATGGCTGTGGTGGACACAGTAAT
CGGGGGTCGCCTACGGCTCCTCTACGAGGATGGTGACAGTGACGACGACTTCTGGTGCCACATGTGGAGCCCCCTGATCCACCCAGTGGGTTGGTCACGA
CGTGTGGGCCACGGCATCAAGATGTCAGAGAGGCGAAGTGACATGGCCCATCACCCCACCTTCCGGAAGATCTACTGTGATGCCGTTCCTTACCTCTTCA
AGAAGGTACGAGCAGTCTACACAGAAGGCGGTTGGTTTGAGGAAGGGATGAAGCTGGAGGCCATTGACCCCCTGAATCTGGGCAACATCTGCGTGGCAAC
TGTCTGTAAGGTTCTCCTGGATGGATACCTGATGATCTGTGTGGACGGGGGGCCCTCCACAGATGGCTTGGACTGGTTCTGCTACCATGCCTCTTCCCAC
GCCATCTTCCCGGCCACCTTCTGTCAGAAGAATGACATTGAGCTCACACCGCCAAAAGGTTATGAGGCACAGACTTTCAACTGGGAGAACTACTTGGAGA
AGACCAAGTCGAAAGCCGCTCCATCGAGACTCTTTAACATGGATTGCCCAAACCATGGCTTCAAGGTGGGCATGAAGCTGGAGGCCGTGGACCTGATGGA
GCCCCGGCTCATCTGTGTGGCCACGGTGAAACGAGTGGTGCATCGGCTCCTCAGCATCCACTTTGACGGCTGGGACAGCGAGTACGACCAGTGGGTGGAC
TGCGAGTC
CCCAGACATCTACCCCGTCGGCTGGTGTGAGCTCACCGGCTACCAGCTCCAGCCTCCTGTGGCCGCAGGTAAACTACCCAGGTCCCTCTGAG
CAGCCCTGGTAACAAGGGTGGGAAGAAGGGACAGCTGTTCTCCGGCCCCTCCTCCAGCCCCGCCCTCTCCTCATTGCCCAG
AACCGGCCACACCGCTGAA
GGCCAAAGAGGCCACAAAGAAGAAAAAGAAACAGTTTGGGAAGAAAAGGAAAAGAATCCCGCCCACTAAGACGCGACCCCTCAGACAGGGGTCCAAGAAG
CCCCTGCTGGAGGACGACCCTCAGGGTGCCAGGAAGATCTCGTCGGAGCCTGTTCCTGGCGAGATCATTGCTGTGCGTGTGAAGGAAGAGCATCTAGACG
TGGCCTCGCCCGACAAGGCTTCAAGTCCAGAGCTGCCTGTCTCCGTCGAGAACATCAAGCAGGAAACAGACGACTGAGCCTTCCTGCCTCCAGCCTGGCT
TCTAGCTGGAAGCCAGCCCAGCGTTTCTCTACCACCACCACCATGCCTCCACCTGACTTTGGCTTGGAGACTGATCCTCTCTGTGTAAATTCTGCCCGGT
GCTGTGAAGGCTGGACGGTGGAGGACCTGCTGGGGTCTCCTGGGACCCGCCTGTTGCTTCTGCCCTCCCCTGTGGAAAGGTCTATATGACGGGCCGCCTG
AGGCCCCAGAACTCGTCTGTGAACCACCTTTTCCAGCCAGAGTTCCCAAAGCTGGAACGCTAGCTGCCTGCTCTTCCTTAAGATGGCCTCCCCCCGACCC
GCCACGGCCCTCAGTTGCCAGGGATGGGGCCACCACTGTCACACTGTGGAATACAAGACAGTGAACTCTGTCTGCCTGAACGAGCCATGTAAATTAAGTT
CTAGAGCAGCTCTCTGAGCAGGATAAGGTCCCCTGACAGTGAGTTGTGTGGTGGGGGCAGCCTCTGCCTCAAAAATTCACCAAGCAGAATGCCTCTCAGC
CTCATGTGTTGGTCCTCTGCTCCTCCTAGCTCCCCAGGGATGTTGGGGACCCAGCTTGTCTCGGCAGCTAAGAAGCAGTGACCAGGATGTGGATTTTGGC
GACCTGTGTGGTGGCCTTGAGCTGCTTTCTGTGTTTGTGAGGACTGACTCCCATTTCCTAAAGGAAATGCCCCCGGGGAGGACATTGGGAGGAAGATGGC
CTGAGTGTGCACTTTGGCTCTGCTACCTGCTCCTGAAGCCCCGCTAAAAATAATTCATCCAAGATTCCTTTGTAGTTAAAGGGTCCAGTTCTGACTGGAG
CCTCTAGAGAGCTGGGCTTGTATGTTCTTTTGGCCTTTTGTTCCTACCTAAATGAAGAAACCATGCCTGGAGGGGCCGTGAACACAGAACCCTCAAGACA
AGGATGACAGAGCTGGAGGACACATCTAGCTGCCATTGCAACCTCACTGGGCTCCCCAGACTCTGTGTGTGAGAAATTAAACCCCCTGCTTGCTTGA
  • refseq_L3MBTL2.F2 (forward primer)
  • refseq_L3MBTL2.R2 (reverse primer)
  • Single exon skipping

Frame 0

GRPIWLPAPGDAWRN*GLMEKPRSIEETPSSEP
MEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLE
ESSEAENEDREAGELPTSPLHLLSPGTPRSLDG
SGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCS
RSYSSNSKKASILARLQGKPPTKKAKVLHKAAWS
AKIGAFLHSQGTGQLADGTPTGQDALVLGFDWG
KFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMK
VEVLNSDAVLPSRVYWIASVIQTAGYRVLLRYEG
FENDASHDFWCNLGTVDVHPIGWCAINSKILVP
PRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKM
VESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVI
GGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSR
RVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLF
KKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVAT
VCKVLLDGYLMICVDGGPSTDGLDWFCYHASSH
AIFPATFCQKNDIELTPPKGYEAQTFNWENYLE
KTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLME
PRLICVATVKRVVHRLLSIHFDGWDSEYDQWVD
CES
PDIYPVGWCELTGYQLQPPVAAGKLPRSL*
AALVTRVGRRDSCSPAPPPAPPSPHCP
EPATPLK
AKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKK
PLLEDDPQGARKISSEPVPGEIIAVRVKEEHLD
VASPDKASSPELPVSVENIKQETDD*AFLPPAWL
LAGSQPSVSLPPPPCLHLTLAWRLILSV*ILPG
AVKAGRWRTCWGLLGPACCFCPPLWKGLYDGPP
EAPELVCEPPFPARVPKAGTLAACSSLRWPPPDP
PRPSVARDGATTVTLWNTRQ*TLSA*TSHVN*V
LEQLSEQDKVP*Q*VVWWGQPLPQKFTKQNASQ
PHVLVLCSS*LPRDVGDPACLGS*EAVTRMWILA
TCVVALSCFLCL*GLTPIS*RKCPRGGHWEEDG
LSVHFGSATCS*SPAKNNSSKIPL*LKGPVLTG
ASRELGLYVLLAFCSYLNEETMPGGAVNTEPSRQ
G*QSWRTHLAAIATSLGSPDSVCEKLNPLLA*

Frame 1

AGQYGFLHLVTLGETEVSWRSPGVLRRPHLQNQ
WRKRKMTTWSCLVAMIVSGVITAVWAVRAAPIW
RSQVKQKMRIGKQGNCRPPRCICSALGLLAPWMA
VVLSQLSVRCVVSWVQGKPSSPRPRGSAASPAP
GATPPTPRKPVSWLGYRENHRPKKPKSCTRLPG
LPKLEPSSTLKGQDSWQMGHQQDKTLWSWASTGG
SS*RITVTRLLPSAVSSTSHSMTSGRM**KG*R
WRCSTVMLCSPAGCTGSPLSSRQQGIGCCFGMK
ALKMTPAMTSGATWEQWMSTPLAGVPSTARS*CP
HGPSMPSSPTGRATS*NGWWAPGRFPWISTSRW
WRA*STPLGRACGWKWWTSPRCHALAWLWWTQ*
SGVAYGSSTRMVTVTTTSGATCGAP*STQWVGHD
VWATASRCQRGEVTWPITPPSGRSTVMPFLTSS
RRYEQSTQKAVGLRKG*SWRPLTP*IWATSAWQ
LSVRFSWMDT**SVWTGGPPQMAWTGSATMPLPT
PSSRPPSVRRMTLSSHRQKVMRHRLSTGRTTWR
RPSRKPLHRDSLTWIAQTMASRWA*SWRPWT*W
SPGSSVWPR*NEWCIGSSASTLTAGTASTTSGWT
AS
PQTSTPSAGVSSPATSSSLLWPQVNYPGPSE
QPW*QGWEEGTAVLRPLLQPRPLLIAQ
NRPHR*
RPKRPQRRKRNSLGRKGKESRPLRRDPSDRGPRS
PCWRTTLRVPGRSRRSLFLARSLLCV*RKSI*T
WPRPTRLQVQSCLSPSRTSSRKQTTEPSCLQPG
F*LEASPAFLYHHHHAST*LWLGD*SSLCKFCPV
L*RLDGGGPAGVSWDPPVASALPCGKVYMTGRL
RPQNSSVNHLFQPEFPKLER*LPALP*DGLPPT
RHGPQLPGMGPPLSHCGIQDSELCLPERAM*IKF
*SSSLSRIRSPDSELCGGGSLCLKNSPSRMPLS
LMCWSSAPPSSPGMLGTQLVSAAKKQ*PGCGFW
RPVWWP*AAFCVCED*LPFPKGNAPGEDIGRKMA
*VCTLALLPAPEAPLKIIHPRFLCS*RVQF*LE
PLESWACMFFWPFVPT*MKKPCLEGP*TQNPQD
KDDRAGGHI*LPLQPHWAPQTLCVRN*TPCLL

Frame 2

QANMASCTW*RLAKLRSHGEAPEY*GDPIFRTN
GGRGR*RLGAVWWL**FPEL*QQCGQ*EQLLSG
GVK*SRK*GSGSRGTADLPAAFAQPWDSSLLGW
QWF*ASCL*DVWYRGYKGSLLLQDQEVLQRLLLQ
ELLLQLQESQYLG*VTGKTTDQKSQSPAQGCLV
CQNWSLPPLSRDRTAGRWDTNRTRRSGLGLRLG
EVPEGSQLQGCSRQLFQARPTL*PVGGCDERDEG
GGAQQ*CCAPQPGVLDRLCHPDSRVSGAASV*R
L*K*RQP*LLVQPGNSGCPPHWLVCHQQQDPSA
PTDHPCQVHRLEGLPHETAGGLQDASRGFPHQDG
GEHEVPL*AGHAAGSGGQVPGVTHSHGCGGHSN
RGSPTAPLRGW*Q*RRLLVPHVEPPDPPSGLVT
TCGPRHQDVREAK*HGPSPHLPEDLL*CRSLPLQ
EGTSSLHRRRLV*GRDEAGGH*PPESGQHLRGN
CL*GSPGWIPDDLCGRGALHRWLGLVLLPCLFP
RHLPGHLLSEE*H*AHTAKRL*GTDFQLGELLGE
DQVESRSIETL*HGLPKPWLQGGHEAGGRGPDG
APAHLCGHGETSGASAPQHPL*RLGQRVRPVGG
LRV
PRHLPRRLV*AHRLPAPASCGRR*TTQVPLS
SPGNKGGKKGQLFSGPSSSPALSSLPR
TGHTAE
GQRGHKEEKETVWEEKEKNPAH*DATPQTGVQE
APAGGRPSGCQEDLVGACSWRDHCCACEGRASRR
GLARQGFKSRAACLRREHQAGNRRLSLPASSLA
SSWKPAQRFSTTTTMPPPDFGLETDPLCVNSAR
CCEGWTVEDLLGSPGTRLLLLPSPVERSI*RAA*
GPRTRL*TTFSSQSSQSWNASCLLFLKMASPRP
ATALSCQGWGHHCHTVEYKTVNSVCLNEPCKLS
SRAAL*AG*GPLTVSCVVGAASASKIHQAECLSA
SCVGPLLLLAPQGCWGPSLSRQLRSSDQDVDFG
DLCGGLELLSVFVRTDSHFLKEMPPGRTLGGRW
PECALWLCYLLLKPR*K*FIQDSFVVKGSSSDWS
L*RAGLVCSFGLLFLPK*RNHAWRGREHRTLKT
RMTELEDTSSCHCNLTGLPRLCV*EIKPPACL

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