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Sequences

Sequence NM_194456

GCTCCGGCTCAGCCGCTGGCACCCCCACCGCCACCACCCTAGTCTCCTAGTCGCCTGCCACCAGCCCCTGAGAGACTGCAGGTCCAGTGAAAAGGAGCAG GAACGGCAGCAGCCCGGCCGCCGACCCGGAAGCTCTTTCACCGCCAACCGCGAGGCTGCAAAGGGTGTGAACCCGGAAGCGATTTCATAGCCACGGTGAC TGTCCCACCCATTTAGTTGAATGTAGCGGCCAGAGAGGCACTCGCGGCAGCCCGTACGGGTGGGACCTCTCGGTGTCCTTCGGGAAACAGGAGGAGCAAG TTCGACTCCAGCGAGGGAAAACGGAGGTGGGAGACTGAACCATCTCCACATCTAGTTGCCCCAGGTTTTTGGCTTTCATCGCTTTTTCTACATGTTTTTA GCCTCACCAGAAGTCTTTCATCTCGGTGGTCCAACTCAGGATCTCAGCCTCATTATTTTCTTACCCTTCTGGAGTGCATATGTGCCTTTACAGTTTCTGT TTGCAAACGCTGTCTAGCATACTAAGAGGATGTTAGCAAACCTGTTCCATGGACACTAAATGGCAGTTGTACATCTCCCCTCATCAGTCATAGTGACAAC CAGAAATGCCCTCCATATTTTCCAGTGATCCCAGTCTTCAATGCGTCTGTCTCATAATTTGTAAACGTTTATTATCTTGAAGTCATTGTTAATCTGTGGT GAAAAGTAATTGCTAAATAGAAATTCTGAGAAGAAAAAGGCCTCATCCTTTTCACATGATGTAGGAAGGTCTGTTGCATGAGCAATGGGAAATCCAGAAA ACATAGAAGATGCATATGTTGCTGTTATTCGTCCAAAGAATACTGCCAGTCTCAATTCTCGGGAATACAGAGCTAAGTCATATGAAATTTTGTTGCATGA AGTTCCCATTGAAGGACAGAAAAAAAAGAGAAAGAAAGTTTTATTGGAAACGAAACTTCAAGGCAACAGTGAAATAACACAAGGCATATTGGATTACGTA GTAGAAACCACCAAACCAATTTCTCCTGCAAACCAGGGTATCAGAGGAAAACGAGTTGTACTAATGAAAAAATTTCCTCTGGATGGAGAGAAGATGGGCA GAGAAGCATCATTATTTATTGTTCCATCAGTTGTCAAAGATAATACTAAATACACATATACCCCAGGATGCCCAATTTTTTACTGCTTACAAGATATTAT GCGAGTCTGTAGTGAATCCAGTACTCATTTTGCTACACTTACAGCAAGGATGTTAATAGCCTTGGATAAGTGGTTAGATGAACGTCATGCACAATCTCAC TTTATTCCAGCTTTATTCCGACCTTCTCCTCTTGAGCGGATAAAAACTAATGTCATAAATCCTGCATATGCTACTGAATCAGGTCAGACAGAAAACTCAC TACATATGGGCTATAGTGCACTAGAAATAAAGAGTAAAATGTTAGCCCTAGAGAAAGCAGATACCTGTATTTACAACCCTTTGTTTGGATCAGATCTTCA GTATACAAATCGGGTAGATAAAGTGGTAATAAATCCATACTTTGGTCTAGGAGCTCCAGACTACTCAAAAATCCAAATACCTAAACAGGAAAAATGGCAG AGAAGCATGAGCAGTGTCACAGAAGACAAGGAACGACAGTGGGTAGATGATTTTCCTCTCCACCGAAGCGCCTGTGAAGGAGATTCAGAATTACTAAGCC GTCTTCTCAGTGAAAGATTTTCAGTCAACCAGTTAGATAGTGACCACTGGGCACCCATTCATTATGCATGCTGGTATGGAAAAGTTGAGGCCACTCGCAT ATTGTTAGAGAAAGGAAAGTGCAATCCAAACCTTTTAAATGGACAACTTAGTTCTCCTCTTCATTTTGCTGCTGGAGGAGGACATGCTGAAATAGTACAG ATTCTCCTAAACCACCCAGAAACGGATAGACATATAACAGACCAACAAGGAAGATCTCCATTAAATATTTGTGAAGAAAACAAACAAAACAACTGGGAAG AAGCTGCAAAATTGTTGAAGGAAGCAATTAACAAACCATATGAAAAAGTTCGAATATACAGAATGGATGGGTCATATCGTTCTGTTGAATTGAAGCATGG AAATAATACCACAGTGCAGCAGATAATGGAAGGAATGCGTCTCTCTCAAGAAACTCAGCAATATTTCACTATATGGATTTGTTCAGAAAACCTCAGCCTT CAACTCAAACCATATCATAAACCCTTGCAACATGTTCGTGACTGGCCAGAAATACTTGCTGAATTGACTAATCTGGATCCTCAAAGGGAAACACCTCAGC TTTTTCTAAGAAGAGATGTGAGACTTCCCTTGGAAGTTGAAAAACAGATTGAAGACCCACTAGCTATTCTTATTCTCTTTGATGAAGCCAGATATAATTT ATTGAAGGGCTTTTATACAGCTCCTGATGCTAAGCTGATAACATTGGCAAGTCTGCTTTTGCAAATAGTCTATGGAAATTATGAGAGTAAAAAACACAAG CAAGGTTTCCTAAATGAAGAAAATCTAAAATCCATCGTACCTGTTACCAAACTGAAAAGTAAGGCACCTCACTGGACAAATCGCATACTTCATGAATACA AGAATCTCAGTACAAGTGAAGGTGTCAGTAAAGAAATGCATCACCTTCAGCGCATGTTCTTACAGAATTGCTGGGAAATTCCTACTTATGGAGCAGCATT TTTCACAGGACAGATATTTACAAAGGCAAGCCCCAGCAATCATAAAGTCATCCCTGTGTATGTAGGAGTGAATATAAAAGGACTTCATCTCCTCAACATG GAAACTAAGGCTTTACTCATCAGTCTTAAGTATGGTTGTTTTATGTGGCAATTGGGAGATACTGATACTTGTTTTCAGATCCATAGCATGGAAAATAAAA TGAGCTTTATAGTACATACAAAACAGGCTGGTCTCGTGGTAAAACTGTTAATGAAGCTAAATGGACAGTTAATGCCCACTGAAAGAAATTCATGAAAGAG AAGTAACTGTTACTCAAGCCACCACATTTTGTAATGCAGAGTTTTTTTTCCGTGAAAGATTTCTTAAAATATTACTTTTGGCCGAGCATGGTGGCTCACC CCTGTAATTCCAGCACTTTGGGAGGCTGGGGCAGGCGGATCACCTGAAGTCAGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACAAA AATACAAAAATTAGCTGGGTGTGGTGGCGGGCGCCTATAATCCTAGCTACTAGGGAGGCCAAGGTGGGAGATCGCTTAAACCCAGGAGGTGGAGGTTGTA GTGAGCCAAGATTGCACCACGGCACGCTAGCCTGGGTGACACAGCAAGACTCCATCTCAAAAAAAAAAAAAAATTACTTTCAACAAGGCATATAGTCTCT TGTAATATATATGTATACTATTACATTGTACAGAATCTGTACTTATGTTTGGTGTGTAATATACCAATTAGTTTTATATAATATCCTCATAAGCTATTCT AATTTTTGAGAGAAACACAAAAAGTTATAGATTGATAGTCTGTATAATATTAGACAAAATAGTAAGCTTTATAAAAAGTTATTTTTGGTAAATGGTAAGG AATTTGGGGTGGAATGTGATGAGATTAAAATGTAGCTTTGGTATAACTTCATGTGTATTTCAAAATATACTGAACGTCAACATGATTTGAATAAAGAAAA TGTATTTTCTACTTGAACCACATAACACTGTTATTTAAAACAGTTTTCTGCAGTCTATAAACATTTCTCAACATTTTTTTAAAAGTCTTAGTTAAAATGT AAATCTGATATACAGTAGTGTTTCTCAAAGTATAGTTCATGAACTCCTTGCATCATAATTACCTAGATGCCTCTTAAAAATGAAGATTTCAGAGACCCAT TCTAAACAAGGGCATTCACTCTCTGGAAGTAGCATGGCCTTGTGAACTTAAATTTGGTTTTGTTTTTTCTTTTTTGCTGTTAGAATAATTTCAGACCCAA TAAGGAATTTCGATTATTAAAGTTGAGAAATTTCACAAAACTGCCTGGCACACAAGCACACACATACATAGACACATTTTAAGTGATAATCTCTTGATAT TAGAAGTTGCATTTGTTAAATACATGCTGTATTTTTTATGAGTTGACTTAATAGTTTATGTATATTGACTTTGCTTTGTAGGAAGTAAATCACCAGATAT CTTATTGTTTCATTTAGGAAAGTAGTGATATAGATGAAGAGCCAACTTGATGAATGTGCTATTCATAAGCTAGAAACTACAGTTTTTCCAAACTAATAAA CTGATGAATTCTAAATAAGTTCAGAGATATAGTCATATTTAAAGTTGTCCTACAGTTTGCAGATAATTTTTATATTACTATTCTTCACATTAACTTCTGC TTATTTTTAATGGTACTATATGTAGGCCTTATTAAAATTAAGATTGTATGGTTAAGTAAAGTTAACAAGAAAGCCTGATTTATCTTTAATTCTGTGCTAG GTACTTTTGATTCTACATGAACAATACCCTTTTCAGTTCCCTTCATTCTAATGTCCTCAACTGTTACCAAATACCCTGTTGACTCCCAAACCTAAGATTT TAGCCTCAACTTCTTTTCTGAACTTCAAATCTTAATTTCCAAGTTATACTTGTTCTAGGTCCATCTAAATGGTCTACAGAGAACTTCAGTTGAATCATAG CTGGAAACAGAATTTATTTCCTCTATTTGCTTCATTCTGTCCTTCCACTATATTCCCTATTT

refseq_KRIT1.F7 (forward primer)
refseq_KRIT1.R7 (reverse primer)
Intron retention

Frame 0

APAQPLAPPPPPP*SPSRLPPAPERLQVQ*KGA GTAAARPPTRKLFHRQPRGCKGCEPGSDFIATVT VPPI*LNVAAREALAAARTGGTSRCPSGNRRSK FDSSEGKRRWETEPSPHLVAPGFWLSSLFLHVF SLTRSLSSRWSNSGSQPHYFLTLLECICAFTVSV CKRCLAY*EDVSKPVPWTLNGSCTSPLISHSDN QKCPPYFPVIPVFNASVS*FVNVYYLEVIVNLW *KVIAK*KF*EEKGLILFT*CRKVCCMSNGKSRK HRRCICCCYSSKEYCQSQFSGIQS*VI*NFVA* SSH*RTEKKEKESFIGNETSRQQ*NNTRHIGLR SRNHQTNFSCKPGYQRKTSCTNEKISSGWREDGQ RSIIIYCSISCQR*Y*IHIYPRMPNFLLLTRYY ASL**IQYSFCYTYSKDVNSLG*VVR*TSCTIS LYSSFIPTFSS*ADKN*CHKSCICY*IRSDRKLT TYGL*CTRNKE*NVSPRESRYLYLQPFVWIRSS VYKSGR*SGNKSILWSRSSRLLKNPNT*TGKMA EKHEQCHRRQGTTVGR*FSSPPKRL*RRFRITKP SSQ*KIFSQPVR**PLGTHSLCMLVWKS*GHSH IVRERKVQSKPFKWTT*FSSSFCCWRRTC*NST DSPKPPRNG*TYNRPTRKISIKYL*RKQTKQLGR SCKIVEGSN*QTI*KSSNIQNGWVISFC*IEAW K*YHSAADNGRNASLSRNSAIFHYMDLFRKPQP STQTIS*TLATCS*LARNTC*ID*SGSSKGNTSA FSKKRCETSLGS*KTD*RPTSYSYSL**SQI*F IEGLLYSS*C*ADNIGKSAFANSLWKL*E*KTQ ARFPK*RKSKIHRTCYQTEK*GTSLDKSHTS*IQ ESQYK*RCQ*RNASPSAHVLTELLGNSYLWSSI FHRTDIYKGKPQQS*SHPCVCRSEYKRTSSPQH GN*GFTHQS*VWLFYVAIGRY*YLFSDP*HGK*N ELYSTYKTGWSRGKTVNEAKWTVNAH*KKFMKE K*LLLKPPHFVMQSFFSVKDFLKYYFWPSMVAH PCNSSTLGGWGRRIT*SQSSRPAWPTW*NPVSTK IQKLAGCGGGRL*S*LLGRPRWEIA*TQEVEVV VSQDCTTAR*PG*HSKTPSQKKKKITFNKAYSL L*YICILLHCTESVLMFGV*YTN*FYIISS*AIL IFERNTKSYRLIVCIILDKIVSFIKSYFW*MVR NLGWNVMRLKCSFGITSCVFQNILNVNMI*IKK MYFLLEPHNTVI*NSFLQSINISQHFFKSLS*NV NLIYSSVSQSIVHELLAS*LPRCLLKMKISETH SKQGHSLSGSSMAL*T*IWFCFFFFAVRIISDP IRNFDY*S*EISQNCLAHKHTHT*THFK**SLDI RSCIC*IHAVFFMS*LNSLCILTLLCRK*ITRY LIVSFRKVVI*MKSQLDECAIHKLETTVFPN** TDEF*ISSEI*SYLKLSYSLQIIFILLFFTLTSA YF*WYYM*ALLKLRLYG*VKLTRKPDLSLILC* VLLILHEQYPFQFPSF*CPQLLPNTLLTPKPKI LASTSFLNFKS*FPSYTCSRSI*MVYRELQLNHS WKQNLFPLFASFCPSTIFPI

Frame 1

LRLSRWHPHRHHPSLLVACHQPLRDCRSSEKEQ ERQQPGRRPGSSFTANREAAKGVNPEAIS*PR* LSHPFS*M*RPERHSRQPVRVGPLGVLRETGGAS STPARENGGGRLNHLHI*LPQVFGFHRFFYMFL ASPEVFHLGGPTQDLSLIIFLPFWSAYVPLQFL FANAV*HTKRMLANLFHGH*MAVVHLPSSVIVTT RNALHIFQ*SQSSMRLSHNL*TFIILKSLLICG EK*LLNRNSEKKKASSFSHDVGRSVA*AMGNPE NIEDAYVAVIRPKNTASLNSREYRAKSYEILLHE VPIEGQKKKRKKVLLETKLQGNSEITQGILDYV VETTKPISPANQGIRGKRVVLMKKFPLDGEKMG REASLFIVPSVVKDNTKYTYTPGCPIFYCLQDIM RVCSESSTHFATLTARMLIALDKWLDERHAQSH FIPALFRPSPLERIKTNVINPAYATESGQTENS LHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQ YTNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQ RSMSSVTEDKERQWVDDFPLHRSACEGDSELLS RLLSERFSVNQLDSDHWAPIHYACWYGKVEATRI LLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQ ILLNHPETDRHITDQQGRSPLNICEENKQNNWE EAAKLLKEAINKPYEKVRIYRMDGSYRSVELKHG NNTTVQQIMEGMRLSQETQQYFTIWICSENLSL QLKPYHKPLQHVRDWPEILAELTNLDPQRETPQ LFLRRDVRLPLEVEKQIEDPLAILILFDEARYNL LKGFYTAPDAKLITLASLLLQIVYGNYESKKHK QGFLNEENLKSIVPVTKLKSKAPHWTNRILHEY KNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAF FTGQIFTKASPSNHKVIPVYVGVNIKGLHLLNM ETKALLISLKYGCFMWQLGDTDTCFQIHSMENK MSFIVHTKQAGLVVKLLMKLNGQLMPTERNS*KR SNCYSSHHIL*CRVFFP*KIS*NITFGRAWWLT PVIPALWEAGAGGSPEVRVQDQPGQHGETLSLQ KYKN*LGVVAGAYNPSY*GGQGGRSLKPRRWRL* *AKIAPRHASLGDTARLHLKKKKKLLSTRHIVS CNIYVYYYIVQNLYLCLVCNIPISFI*YPHKLF *FLRETQKVID**SV*Y*TK**AL*KVIFGKW*G IWGGM**D*NVALV*LHVYFKIY*TST*FE*RK CIFYLNHITLLFKTVFCSL*TFLNIFLKVLVKM *I*YTVVFLKV*FMNSLHHNYLDAS*K*RFQRPI LNKGIHSLEVAWPCELKFGFVFSFLLLE*FQTQ *GISIIKVEKFHKTAWHTSTHIHRHILSDNLLI LEVAFVKYMLYFL*VDLIVYVY*LCFVGSKSPDI LLFHLGK**YR*RANLMNVLFIS*KLQFFQTNK LMNSK*VQRYSHI*SCPTVCR*FLYYYSSH*LL LIFNGTICRPY*N*DCMVK*S*QESLIYL*FCAR YF*FYMNNTLFSSLHSNVLNCYQIPC*LPNLRF *PQLLF*TSNLNFQVILVLGPSKWSTENFS*II AGNRIYFLYLLHSVLPLYSLF

Frame 2

SGSAAGTPTATTLVS*SPATSP*ETAGPVKRSR NGSSPAADPEALSPPTARLQRV*TRKRFHSHGD CPTHLVECSGQRGTRGSPYGWDLSVSFGKQEEQ VRLQRGKTEVGD*TISTSSCPRFLAFIAFSTCF* PHQKSFISVVQLRISASLFSYPSGVHMCLYSFC LQTLSSILRGC*QTCSMDTKWQLYISPHQS**Q PEMPSIFSSDPSLQCVCLIICKRLLS*SHC*SVV KSNC*IEILRRKRPHPFHMM*EGLLHEQWEIQK T*KMHMLLLFVQRILPVSILGNTELSHMKFCCM KFPLKDRKKRERKFYWKRNFKATVK*HKAYWIT* *KPPNQFLLQTRVSEENELY**KNFLWMERRWA EKHHYLLFHQLSKIILNTHIPQDAQFFTAYKIL CESVVNPVLILLHLQQGC**PWISG*MNVMHNLT LFQLYSDLLLLSG*KLMS*ILHMLLNQVRQKTH YIWAIVH*K*RVKC*P*RKQIPVFTTLCLDQIF SIQIG*IKW**IHTLV*ELQTTQKSKYLNRKNGR EA*AVSQKTRNDSG*MIFLSTEAPVKEIQNY*A VFSVKDFQSTS*IVTTGHPFIMHAGMEKLRPLA YC*RKESAIQTF*MDNLVLLFILLLEEDMLK*YR FS*TTQKRIDI*QTNKEDLH*IFVKKTNKTTGK KLQNC*RKQLTNHMKKFEYTEWMGHIVLLN*SM EIIPQCSR*WKECVSLKKLSNISLYGFVQKTSAF NSNHIINPCNMFVTGQKYLLN*LIWILKGKHLS FF*EEM*DFPWKLKNRLKTH*LFLFSLMKPDII Y*RAFIQLLMLS**HWQVCFCK*SMEIMRVKNTS KVS*MKKI*NPSYLLPN*KVRHLTGQIAYFMNT RISVQVKVSVKKCITFSACSYRIAGKFLLMEQH FSQDRYLQRQAPAIIKSSLCM*E*I*KDFISSTW KLRLYSSVLSMVVLCGNWEILILVFRSIAWKIK *AL*YIQNRLVSW*NC**S*MDS*CPLKEIHER EVTVTQATTFCNAEFFFRERFLKILLLAEHGGSP L*FQHFGRLGQADHLKSEFKTSLANMVKPCLYK NTKISWVWWRAPIILATREAKVGDRLNPGGGGC SEPRLHHGTLAWVTQQDSISKKKKNYFQQGI*SL VIYMYTITLYRICTYVWCVIYQLVLYNILISYS NF*EKHKKL*IDSLYNIRQNSKLYKKLFLVNGK EFGVECDEIKM*LWYNFMCISKYTERQHDLNKEN VFST*TT*HCYLKQFSAVYKHFSTFF*KS*LKC KSDIQ*CFSKYSS*TPCIIIT*MPLKNEDFRDP F*TRAFTLWK*HGLVNLNLVLFFLFCC*NNFRPN KEFRLLKLRNFTKLPGTQAHTYIDTF*VIIS*Y *KLHLLNTCCIFYELT**FMYIDFAL*EVNHQI SYCFI*ESSDIDEEPT**MCYS*ARNYSFSKLIN **ILNKFRDIVIFKVVLQFADNFYITILHINFC LFLMVLYVGLIKIKIVWLSKVNKKA*FIFNSVL GTFDST*TIPFSVPFILMSSTVTKYPVDSQT*DF SLNFFSELQILISKLYLF*VHLNGLQRTSVES* LETEFISSICFILSFHYIPY

Sequence NM_194455

GCTCCGGCTCAGCCGCTGGCACCCCCACCGCCACCACCCTAGTCTCCTAGTCGCCTGCCACCAGCCCCTGAGAGACTGCAGGTCCAGTGAAAAGGAGCAG GAACGGCAGCAGCCCGGCCGCCGACCCGGAAGCTCTTTCACCGCCAACCGCGAGGCTGCAAAGGGTGTGAACCCGGAAGCGATTTCATAGCCACGGTAAC GGCGGGGTGGAAAGCTAAGGCCTTTGAAGACCTGGGACCCCGTAGTTTCGGGAGAGGGTGAGGGGTGAATGGTGCTGAGGTGCGAGGAGAGGGAAGGACA GTAAAGAGCAGGTGGGCAGGAGGGTCTCCGACTCCAGAGACCTGAGCTTTTGGGGCGCGGGTGGGAGCGCGGGGGAACCCTCAAGACGGCTTTCTTTTGG CGACTGAGGGTTTTTCTGCCACAGGAAGCTGGGCCGGGCTGCTGTGCCTGGGAGGAGGGAAGGAGGAATGAGAAAGCGGTGACGGTCCCTGCCCCCCCTC GCCAGGTGACTGTCCCACCCATTTAGTTGAATGTAGCGGCCAGAGAGGCACTCGCGGCAGCCCGTACGGGTGGGACCTCTCGGTGTCCTTCGGGAAACAG GAGGAGCAAGTTCGACTCCAGCGAGGGAAAACGGAGCCTCACCAGAAGTCTTTCATCTCGGTGGTCCAACTCAGGATCTCAGCCTCATTATTTTCTTACC CTTCTGGAGTGCATATGTGCCTTTACAGTTTCTGTTTGCAAACGCTGTCTAGCATACTAAGAGGATGTTAGCAAACCTGTTCCATGGACACTAAATGGCA GTTGTACATCTCCCCTCATCAGTCATAGTGACAACCAGAAATGCCCTCCATATTTTCCAGTGATCCCAGTCTTCAATGCGTCTGTCTCATAATTTGTAAA CGTTTATTATCTTGAAGTCATTGTTAATCTGTGGTGAAAAGTAATTGCTAAATAGAAATTCTGAGAAGAAAAAGGCCTCATCCTTTTCACATGATGTAGG AAGGTCTGTTGCATGAGCAATGGGAAATCCAGAAAACATAGAAGATGCATATGTTGCTGTTATTCGTCCAAAGAATACTGCCAGTCTCAATTCTCGGGAA TACAGAGCTAAGTCATATGAAATTTTGTTGCATGAAGTTCCCATTGAAGGACAGAAAAAAAAGAGAAAGAAAGTTTTATTGGAAACGAAACTTCAAGGCA ACAGTGAAATAACACAAGGCATATTGGATTACGTAGTAGAAACCACCAAACCAATTTCTCCTGCAAACCAGGGTATCAGAGGAAAACGAGTTGTACTAAT GAAAAAATTTCCTCTGGATGGAGAGAAGATGGGCAGAGAAGCATCATTATTTATTGTTCCATCAGTTGTCAAAGATAATACTAAATACACATATACCCCA GGATGCCCAATTTTTTACTGCTTACAAGATATTATGCGAGTCTGTAGTGAATCCAGTACTCATTTTGCTACACTTACAGCAAGGATGTTAATAGCCTTGG ATAAGTGGTTAGATGAACGTCATGCACAATCTCACTTTATTCCAGCTTTATTCCGACCTTCTCCTCTTGAGCGGATAAAAACTAATGTCATAAATCCTGC ATATGCTACTGAATCAGGTCAGACAGAAAACTCACTACATATGGGCTATAGTGCACTAGAAATAAAGAGTAAAATGTTAGCCCTAGAGAAAGCAGATACC TGTATTTACAACCCTTTGTTTGGATCAGATCTTCAGTATACAAATCGGGTAGATAAAGTGGTAATAAATCCATACTTTGGTCTAGGAGCTCCAGACTACT CAAAAATCCAAATACCTAAACAGGAAAAATGGCAGAGAAGCATGAGCAGTGTCACAGAAGACAAGGAACGACAGTGGGTAGATGATTTTCCTCTCCACCG AAGCGCCTGTGAAGGAGATTCAGAATTACTAAGCCGTCTTCTCAGTGAAAGATTTTCAGTCAACCAGTTAGATAGTGACCACTGGGCACCCATTCATTAT GCATGCTGGTATGGAAAAGTTGAGGCCACTCGCATATTGTTAGAGAAAGGAAAGTGCAATCCAAACCTTTTAAATGGACAACTTAGTTCTCCTCTTCATT TTGCTGCTGGAGGAGGACATGCTGAAATAGTACAGATTCTCCTAAACCACCCAGAAACGGATAGACATATAACAGACCAACAAGGAAGATCTCCATTAAA TATTTGTGAAGAAAACAAACAAAACAACTGGGAAGAAGCTGCAAAATTGTTGAAGGAAGCAATTAACAAACCATATGAAAAAGTTCGAATATACAGAATG GATGGGTCATATCGTTCTGTTGAATTGAAGCATGGAAATAATACCACAGTGCAGCAGATAATGGAAGGAATGCGTCTCTCTCAAGAAACTCAGCAATATT TCACTATATGGATTTGTTCAGAAAACCTCAGCCTTCAACTCAAACCATATCATAAACCCTTGCAACATGTTCGTGACTGGCCAGAAATACTTGCTGAATT GACTAATCTGGATCCTCAAAGGGAAACACCTCAGCTTTTTCTAAGAAGAGATGTGAGACTTCCCTTGGAAGTTGAAAAACAGATTGAAGACCCACTAGCT ATTCTTATTCTCTTTGATGAAGCCAGATATAATTTATTGAAGGGCTTTTATACAGCTCCTGATGCTAAGCTGATAACATTGGCAAGTCTGCTTTTGCAAA TAGTCTATGGAAATTATGAGAGTAAAAAACACAAGCAAGGTTTCCTAAATGAAGAAAATCTAAAATCCATCGTACCTGTTACCAAACTGAAAAGTAAGGC ACCTCACTGGACAAATCGCATACTTCATGAATACAAGAATCTCAGTACAAGTGAAGGTGTCAGTAAAGAAATGCATCACCTTCAGCGCATGTTCTTACAG AATTGCTGGGAAATTCCTACTTATGGAGCAGCATTTTTCACAGGACAGATATTTACAAAGGCAAGCCCCAGCAATCATAAAGTCATCCCTGTGTATGTAG GAGTGAATATAAAAGGACTTCATCTCCTCAACATGGAAACTAAGGCTTTACTCATCAGTCTTAAGTATGGTTGTTTTATGTGGCAATTGGGAGATACTGA TACTTGTTTTCAGATCCATAGCATGGAAAATAAAATGAGCTTTATAGTACATACAAAACAGGCTGGTCTCGTGGTAAAACTGTTAATGAAGCTAAATGGA CAGTTAATGCCCACTGAAAGAAATTCATGAAAGAGAAGTAACTGTTACTCAAGCCACCACATTTTGTAATGCAGAGTTTTTTTTCCGTGAAAGATTTCTT AAAATATTACTTTTGGCCGAGCATGGTGGCTCACCCCTGTAATTCCAGCACTTTGGGAGGCTGGGGCAGGCGGATCACCTGAAGTCAGAGTTCAAGACCA GCCTGGCCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAATTAGCTGGGTGTGGTGGCGGGCGCCTATAATCCTAGCTACTAGGGAGGCCAAGGT GGGAGATCGCTTAAACCCAGGAGGTGGAGGTTGTAGTGAGCCAAGATTGCACCACGGCACGCTAGCCTGGGTGACACAGCAAGACTCCATCTCAAAAAAA AAAAAAAATTACTTTCAACAAGGCATATAGTCTCTTGTAATATATATGTATACTATTACATTGTACAGAATCTGTACTTATGTTTGGTGTGTAATATACC AATTAGTTTTATATAATATCCTCATAAGCTATTCTAATTTTTGAGAGAAACACAAAAAGTTATAGATTGATAGTCTGTATAATATTAGACAAAATAGTAA GCTTTATAAAAAGTTATTTTTGGTAAATGGTAAGGAATTTGGGGTGGAATGTGATGAGATTAAAATGTAGCTTTGGTATAACTTCATGTGTATTTCAAAA TATACTGAACGTCAACATGATTTGAATAAAGAAAATGTATTTTCTACTTGAACCACATAACACTGTTATTTAAAACAGTTTTCTGCAGTCTATAAACATT TCTCAACATTTTTTTAAAAGTCTTAGTTAAAATGTAAATCTGATATACAGTAGTGTTTCTCAAAGTATAGTTCATGAACTCCTTGCATCATAATTACCTA GATGCCTCTTAAAAATGAAGATTTCAGAGACCCATTCTAAACAAGGGCATTCACTCTCTGGAAGTAGCATGGCCTTGTGAACTTAAATTTGGTTTTGTTT TTTCTTTTTTGCTGTTAGAATAATTTCAGACCCAATAAGGAATTTCGATTATTAAAGTTGAGAAATTTCACAAAACTGCCTGGCACACAAGCACACACAT ACATAGACACATTTTAAGTGATAATCTCTTGATATTAGAAGTTGCATTTGTTAAATACATGCTGTATTTTTTATGAGTTGACTTAATAGTTTATGTATAT TGACTTTGCTTTGTAGGAAGTAAATCACCAGATATCTTATTGTTTCATTTAGGAAAGTAGTGATATAGATGAAGAGCCAACTTGATGAATGTGCTATTCA TAAGCTAGAAACTACAGTTTTTCCAAACTAATAAACTGATGAATTCTAAATAAGTTCAGAGATATAGTCATATTTAAAGTTGTCCTACAGTTTGCAGATA ATTTTTATATTACTATTCTTCACATTAACTTCTGCTTATTTTTAATGGTACTATATGTAGGCCTTATTAAAATTAAGATTGTATGGTTAAGTAAAGTTAA CAAGAAAGCCTGATTTATCTTTAATTCTGTGCTAGGTACTTTTGATTCTACATGAACAATACCCTTTTCAGTTCCCTTCATTCTAATGTCCTCAACTGTT ACCAAATACCCTGTTGACTCCCAAACCTAAGATTTTAGCCTCAACTTCTTTTCTGAACTTCAAATCTTAATTTCCAAGTTATACTTGTTCTAGGTCCATC TAAATGGTCTACAGAGAACTTCAGTTGAATCATAGCTGGAAACAGAATTTATTTCCTCTATTTGCTTCATTCTGTCCTTCCACTATATTCCCTATTT

refseq_KRIT1.F7 (forward primer)
refseq_KRIT1.R7 (reverse primer)
Intron retention

Frame 0

APAQPLAPPPPPP*SPSRLPPAPERLQVQ*KGA GTAAARPPTRKLFHRQPRGCKGCEPGSDFIATVT AGWKAKAFEDLGPRSFGRG*GVNGAEVRGEGRT VKSRWAGGSPTPET*AFGARVGARGNPQDGFLL ATEGFSATGSWAGLLCLGGGKEE*ESGDGPCPPS PGDCPTHLVECSGQRGTRGSPYGWDLSVSFGKQ EEQVRLQRGKTEPHQKSFISVVQLRISASLFSY PSGVHMCLYSFCLQTLSSILRGC*QTCSMDTKWQ LYISPHQS**QPEMPSIFSSDPSLQCVCLIICK RLLS*SHC*SVVKSNC*IEILRRKRPHPFHMM* EGLLHEQWEIQKT*KMHMLLLFVQRILPVSILGN TELSHMKFCCMKFPLKDRKKRERKFYWKRNFKA TVK*HKAYWIT**KPPNQFLLQTRVSEENELY* *KNFLWMERRWAEKHHYLLFHQLSKIILNTHIPQ DAQFFTAYKILCESVVNPVLILLHLQQGC**PW ISG*MNVMHNLTLFQLYSDLLLLSG*KLMS*IL HMLLNQVRQKTHYIWAIVH*K*RVKC*P*RKQIP VFTTLCLDQIFSIQIG*IKW**IHTLV*ELQTT QKSKYLNRKNGREA*AVSQKTRNDSG*MIFLST EAPVKEIQNY*AVFSVKDFQSTS*IVTTGHPFIM HAGMEKLRPLAYC*RKESAIQTF*MDNLVLLFI LLLEEDMLK*YRFS*TTQKRIDI*QTNKEDLH* IFVKKTNKTTGKKLQNC*RKQLTNHMKKFEYTEW MGHIVLLN*SMEIIPQCSR*WKECVSLKKLSNI SLYGFVQKTSAFNSNHIINPCNMFVTGQKYLLN *LIWILKGKHLSFF*EEM*DFPWKLKNRLKTH*L FLFSLMKPDIIY*RAFIQLLMLS**HWQVCFCK *SMEIMRVKNTSKVS*MKKI*NPSYLLPN*KVR HLTGQIAYFMNTRISVQVKVSVKKCITFSACSYR IAGKFLLMEQHFSQDRYLQRQAPAIIKSSLCM* E*I*KDFISSTWKLRLYSSVLSMVVLCGNWEIL ILVFRSIAWKIK*AL*YIQNRLVSW*NC**S*MD S*CPLKEIHEREVTVTQATTFCNAEFFFRERFL KILLLAEHGGSPL*FQHFGRLGQADHLKSEFKT SLANMVKPCLYKNTKISWVWWRAPIILATREAKV GDRLNPGGGGCSEPRLHHGTLAWVTQQDSISKK KKNYFQQGI*SLVIYMYTITLYRICTYVWCVIY QLVLYNILISYSNF*EKHKKL*IDSLYNIRQNSK LYKKLFLVNGKEFGVECDEIKM*LWYNFMCISK YTERQHDLNKENVFST*TT*HCYLKQFSAVYKH FSTFF*KS*LKCKSDIQ*CFSKYSS*TPCIIIT* MPLKNEDFRDPF*TRAFTLWK*HGLVNLNLVLF FLFCC*NNFRPNKEFRLLKLRNFTKLPGTQAHT YIDTF*VIIS*Y*KLHLLNTCCIFYELT**FMYI DFAL*EVNHQISYCFI*ESSDIDEEPT**MCYS *ARNYSFSKLIN**ILNKFRDIVIFKVVLQFAD NFYITILHINFCLFLMVLYVGLIKIKIVWLSKVN KKA*FIFNSVLGTFDST*TIPFSVPFILMSSTV TKYPVDSQT*DFSLNFFSELQILISKLYLF*VH LNGLQRTSVES*LETEFISSICFILSFHYIPY

Frame 1

LRLSRWHPHRHHPSLLVACHQPLRDCRSSEKEQ ERQQPGRRPGSSFTANREAAKGVNPEAIS*PR* RRGGKLRPLKTWDPVVSGEGEG*MVLRCEEREGQ *RAGGQEGLRLQRPELLGRGWERGGTLKTAFFW RLRVFLPQEAGPGCCAWEEGRRNEKAVTVPAPP RQVTVPPI*LNVAAREALAAARTGGTSRCPSGNR RSKFDSSEGKRSLTRSLSSRWSNSGSQPHYFLT LLECICAFTVSVCKRCLAY*EDVSKPVPWTLNG SCTSPLISHSDNQKCPPYFPVIPVFNASVS*FVN VYYLEVIVNLW*KVIAK*KF*EEKGLILFT*CR KVCCMSNGKSRKHRRCICCCYSSKEYCQSQFSG IQS*VI*NFVA*SSH*RTEKKEKESFIGNETSRQ Q*NNTRHIGLRSRNHQTNFSCKPGYQRKTSCTN EKISSGWREDGQRSIIIYCSISCQR*Y*IHIYP RMPNFLLLTRYYASL**IQYSFCYTYSKDVNSLG *VVR*TSCTISLYSSFIPTFSS*ADKN*CHKSC ICY*IRSDRKLTTYGL*CTRNKE*NVSPRESRY LYLQPFVWIRSSVYKSGR*SGNKSILWSRSSRLL KNPNT*TGKMAEKHEQCHRRQGTTVGR*FSSPP KRL*RRFRITKPSSQ*KIFSQPVR**PLGTHSL CMLVWKS*GHSHIVRERKVQSKPFKWTT*FSSSF CCWRRTC*NSTDSPKPPRNG*TYNRPTRKISIK YL*RKQTKQLGRSCKIVEGSN*QTI*KSSNIQN GWVISFC*IEAWK*YHSAADNGRNASLSRNSAIF HYMDLFRKPQPSTQTIS*TLATCS*LARNTC*I D*SGSSKGNTSAFSKKRCETSLGS*KTD*RPTS YSYSL**SQI*FIEGLLYSS*C*ADNIGKSAFAN SLWKL*E*KTQARFPK*RKSKIHRTCYQTEK*G TSLDKSHTS*IQESQYK*RCQ*RNASPSAHVLT ELLGNSYLWSSIFHRTDIYKGKPQQS*SHPCVCR SEYKRTSSPQHGN*GFTHQS*VWLFYVAIGRY* YLFSDP*HGK*NELYSTYKTGWSRGKTVNEAKW TVNAH*KKFMKEK*LLLKPPHFVMQSFFSVKDFL KYYFWPSMVAHPCNSSTLGGWGRRIT*SQSSRP AWPTW*NPVSTKIQKLAGCGGGRL*S*LLGRPR WEIA*TQEVEVVVSQDCTTAR*PG*HSKTPSQKK KKITFNKAYSLL*YICILLHCTESVLMFGV*YT N*FYIISS*AILIFERNTKSYRLIVCIILDKIV SFIKSYFW*MVRNLGWNVMRLKCSFGITSCVFQN ILNVNMI*IKKMYFLLEPHNTVI*NSFLQSINI SQHFFKSLS*NVNLIYSSVSQSIVHELLAS*LP RCLLKMKISETHSKQGHSLSGSSMAL*T*IWFCF FFFAVRIISDPIRNFDY*S*EISQNCLAHKHTH T*THFK**SLDIRSCIC*IHAVFFMS*LNSLCI LTLLCRK*ITRYLIVSFRKVVI*MKSQLDECAIH KLETTVFPN**TDEF*ISSEI*SYLKLSYSLQI IFILLFFTLTSAYF*WYYM*ALLKLRLYG*VKL TRKPDLSLILC*VLLILHEQYPFQFPSF*CPQLL PNTLLTPKPKILASTSFLNFKS*FPSYTCSRSI *MVYRELQLNHSWKQNLFPLFASFCPSTIFPI

Frame 2

SGSAAGTPTATTLVS*SPATSP*ETAGPVKRSR NGSSPAADPEALSPPTARLQRV*TRKRFHSHGN GGVES*GL*RPGTP*FRERVRGEWC*GARRGKD SKEQVGRRVSDSRDLSFWGAGGSAGEPSRRLSFG D*GFFCHRKLGRAAVPGRREGGMRKR*RSLPPL AR*LSHPFS*M*RPERHSRQPVRVGPLGVLRET GGASSTPARENGASPEVFHLGGPTQDLSLIIFLP FWSAYVPLQFLFANAV*HTKRMLANLFHGH*MA VVHLPSSVIVTTRNALHIFQ*SQSSMRLSHNL* TFIILKSLLICGEK*LLNRNSEKKKASSFSHDVG RSVA*AMGNPENIEDAYVAVIRPKNTASLNSRE YRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG NSEITQGILDYVVETTKPISPANQGIRGKRVVLM KKFPLDGEKMGREASLFIVPSVVKDNTKYTYTP GCPIFYCLQDIMRVCSESSTHFATLTARMLIAL DKWLDERHAQSHFIPALFRPSPLERIKTNVINPA YATESGQTENSLHMGYSALEIKSKMLALEKADT CIYNPLFGSDLQYTNRVDKVVINPYFGLGAPDY SKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHR SACEGDSELLSRLLSERFSVNQLDSDHWAPIHY ACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN ICEENKQNNWEEAAKLLKEAINKPYEKVRIYRM DGSYRSVELKHGNNTTVQQIMEGMRLSQETQQY FTIWICSENLSLQLKPYHKPLQHVRDWPEILAEL TNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLA ILILFDEARYNLLKGFYTAPDAKLITLASLLLQ IVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKA PHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQ NCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTD TCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNG QLMPTERNS*KRSNCYSSHHIL*CRVFFP*KIS *NITFGRAWWLTPVIPALWEAGAGGSPEVRVQDQ PGQHGETLSLQKYKN*LGVVAGAYNPSY*GGQG GRSLKPRRWRL**AKIAPRHASLGDTARLHLKK KKKLLSTRHIVSCNIYVYYYIVQNLYLCLVCNIP ISFI*YPHKLF*FLRETQKVID**SV*Y*TK** AL*KVIFGKW*GIWGGM**D*NVALV*LHVYFK IY*TST*FE*RKCIFYLNHITLLFKTVFCSL*TF LNIFLKVLVKM*I*YTVVFLKV*FMNSLHHNYL DAS*K*RFQRPILNKGIHSLEVAWPCELKFGFV FSFLLLE*FQTQ*GISIIKVEKFHKTAWHTSTHI HRHILSDNLLILEVAFVKYMLYFL*VDLIVYVY *LCFVGSKSPDILLFHLGK**YR*RANLMNVLF IS*KLQFFQTNKLMNSK*VQRYSHI*SCPTVCR* FLYYYSSH*LLLIFNGTICRPY*N*DCMVK*S* QESLIYL*FCARYF*FYMNNTLFSSLHSNVLNC YQIPC*LPNLRF*PQLLF*TSNLNFQVILVLGPS KWSTENFS*IIAGNRIYFLYLLHSVLPLYSLF