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Sequences

Sequence NM_194454

GCTCCGGCTCAGCCGCTGGCACCCCCACCGCCACCACCCTAGTCTCCTAGTCGCCTGCCACCAGCCCCTGAGAGACTGCAGGTCCAGTGAAAAGGAGCAG
GAACGGCAGCAGCCCGGCCGCCGACCCGGAAGCTCTTTCACCGCCAACCGCGAGGCTGCAAAGGGTGTGAACCCGGAAGCGATTTCATAGCCACGGTAAC
GGCGGGGTGGAAAGCTAAGGCCTTTGAAGACCTGGGACCCCGTAGTTTCGGGAGAGGGTGAGGGGTGAATGGTGCTGAGGTGCGAGGAGAGGGAAGGACA
GTAAAGAGCAGGTTTTTGGCTTTCATCGCTTTTTCTACATGTTTTTAGCCTCACCAGAAGTCTTTCATCTCGGTGGTCCAACTCAGGATCTCAGCCTCAT
TATTTTCTTACCCTTCTGGAGTGCATATGTGCCTTTACAGTTTCTGTTTGCAAACGCTGTCTAGCATACTAAGAGGATGTTAGCAAACCTGTTCCATGGA
CACTAAATGGCAGTTGTACATCTCCCCTCATCAGTCATAGTGACAACCAGAAATGCCCTCCATATTTTCCAGTGATCCCAGTCTTCAATGCGTCTGTCTC
ATAATTTGTAAACGTTTATTATCTTGAAGTCATTGTTAATCTGTGGTGAAAAGTAATTGCTAAATAGAAATTCTGAGAAGAAAAAGGCCTCATCCTTTTC
ACATGATGTAGGAAGGTCTGTTGCATGAGCAATGGGAAATCCAGAAAACATAGAAGATGCATATGTTGCTGTTATTCGTCCAAAGAATACTGCCAGTCTC
AATTCTCGGGAATACAGAGCTAAGTCATATGAAATTTTGTTGCATGAAGTTCCCATTGAAGGACAGAAAAAAAAGAGAAAGAAAGTTTTATTGGAAACGA
AACTTCAAGGCAACAGTGAAATAACACAAGGCATATTGGATTACGTAGTAGAAACCACCAAACCAATTTCTCCTGCAAACCAGGGTATCAGAGGAAAACG
AGTTGTACTAATGAAAAAATTTCCTCTGGATGGAGAGAAGATGGGCAGAGAAGCATCATTATTTATTGTTCCATCAGTTGTCAAAGATAATACTAAATAC
ACATATACCCCAGGATGCCCAATTTTTTACTGCTTACAAGATATTATGCGAGTCTGTAGTGAATCCAGTACTCATTTTGCTACACTTACAGCAAGGATGT
TAATAGCCTTGGATAAGTGGTTAGATGAACGTCATGCACAATCTCACTTTATTCCAGCTTTATTCCGACCTTCTCCTCTTGAGCGGATAAAAACTAATGT
CATAAATCCTGCATATGCTACTGAATCAGGTCAGACAGAAAACTCACTACATATGGGCTATAGTGCACTAGAAATAAAGAGTAAAATGTTAGCCCTAGAG
AAAGCAGATACCTGTATTTACAACCCTTTGTTTGGATCAGATCTTCAGTATACAAATCGGGTAGATAAAGTGGTAATAAATCCATACTTTGGTCTAGGAG
CTCCAGACTACTCAAAAATCCAAATACCTAAACAGGAAAAATGGCAGAGAAGCATGAGCAGTGTCACAGAAGACAAGGAACGACAGTGGGTAGATGATTT
TCCTCTCCACCGAAGCGCCTGTGAAGGAGATTCAGAATTACTAAGCCGTCTTCTCAGTGAAAGATTTTCAGTCAACCAGTTAGATAGTGACCACTGGGCA
CCCATTCATTATGCATGCTGGTATGGAAAAGTTGAGGCCACTCGCATATTGTTAGAGAAAGGAAAGTGCAATCCAAACCTTTTAAATGGACAACTTAGTT
CTCCTCTTCATTTTGCTGCTGGAGGAGGACATGCTGAAATAGTACAGATTCTCCTAAACCACCCAGAAACGGATAGACATATAACAGACCAACAAGGAAG
ATCTCCATTAAATATTTGTGAAGAAAACAAACAAAACAACTGGGAAGAAGCTGCAAAATTGTTGAAGGAAGCAATTAACAAACCATATGAAAAAGTTCGA
ATATACAGAATGGATGGGTCATATCGTTCTGTTGAATTGAAGCATGGAAATAATACCACAGTGCAGCAGATAATGGAAGGAATGCGTCTCTCTCAAGAAA
CTCAGCAATATTTCACTATATGGATTTGTTCAGAAAACCTCAGCCTTCAACTCAAACCATATCATAAACCCTTGCAACATGTTCGTGACTGGCCAGAAAT
ACTTGCTGAATTGACTAATCTGGATCCTCAAAGGGAAACACCTCAGCTTTTTCTAAGAAGAGATGTGAGACTTCCCTTGGAAGTTGAAAAACAGATTGAA
GACCCACTAGCTATTCTTATTCTCTTTGATGAAGCCAGATATAATTTATTGAAGGGCTTTTATACAGCTCCTGATGCTAAGCTGATAACATTGGCAAGTC
TGCTTTTGCAAATAGTCTATGGAAATTATGAGAGTAAAAAACACAAGCAAGGTTTCCTAAATGAAGAAAATCTAAAATCCATCGTACCTGTTACCAAACT
GAAAAGTAAGGCACCTCACTGGACAAATCGCATACTTCATGAATACAAGAATCTCAGTACAAGTGAAGGTGTCAGTAAAGAAATGCATCACCTTCAGCGC
ATGTTCTTACAGAATTGCTGGGAAATTCCTACTTATGGAGCAGCATTTTTCACAGGACAGATATTTACAAAGGCAAGCCCCAGCAATCATAAAGTCATCC
CTGTGTATGTAGGAGTGAATATAAAAGGACTTCATCTCCTCAACATGGAAACTAAGGCTTTACTCATCAGTCTTAAGTATGGTTGTTTTATGTGGCAATT
GGGAGATACTGATACTTGTTTTCAGATCCATAGCATGGAAAATAAAATGAGCTTTATAGTACATACAAAACAGGCTGGTCTCGTGGTAAAACTGTTAATG
AAGCTAAATGGACAGTTAATGCCCACTGAAAGAAATTCATGAAAGAGAAGTAACTGTTACTCAAGCCACCACATTTTGTAATGCAGAGTTTTTTTTCCGT
GAAAGATTTCTTAAAATATTACTTTTGGCCGAGCATGGTGGCTCACCCCTGTAATTCCAGCACTTTGGGAGGCTGGGGCAGGCGGATCACCTGAAGTCAG
AGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAATTAGCTGGGTGTGGTGGCGGGCGCCTATAATCCTAGCTACTAG
GGAGGCCAAGGTGGGAGATCGCTTAAACCCAGGAGGTGGAGGTTGTAGTGAGCCAAGATTGCACCACGGCACGCTAGCCTGGGTGACACAGCAAGACTCC
ATCTCAAAAAAAAAAAAAAATTACTTTCAACAAGGCATATAGTCTCTTGTAATATATATGTATACTATTACATTGTACAGAATCTGTACTTATGTTTGGT
GTGTAATATACCAATTAGTTTTATATAATATCCTCATAAGCTATTCTAATTTTTGAGAGAAACACAAAAAGTTATAGATTGATAGTCTGTATAATATTAG
ACAAAATAGTAAGCTTTATAAAAAGTTATTTTTGGTAAATGGTAAGGAATTTGGGGTGGAATGTGATGAGATTAAAATGTAGCTTTGGTATAACTTCATG
TGTATTTCAAAATATACTGAACGTCAACATGATTTGAATAAAGAAAATGTATTTTCTACTTGAACCACATAACACTGTTATTTAAAACAGTTTTCTGCAG
TCTATAAACATTTCTCAACATTTTTTTAAAAGTCTTAGTTAAAATGTAAATCTGATATACAGTAGTGTTTCTCAAAGTATAGTTCATGAACTCCTTGCAT
CATAATTACCTAGATGCCTCTTAAAAATGAAGATTTCAGAGACCCATTCTAAACAAGGGCATTCACTCTCTGGAAGTAGCATGGCCTTGTGAACTTAAAT
TTGGTTTTGTTTTTTCTTTTTTGCTGTTAGAATAATTTCAGACCCAATAAGGAATTTCGATTATTAAAGTTGAGAAATTTCACAAAACTGCCTGGCACAC
AAGCACACACATACATAGACACATTTTAAGTGATAATCTCTTGATATTAGAAGTTGCATTTGTTAAATACATGCTGTATTTTTTATGAGTTGACTTAATA
GTTTATGTATATTGACTTTGCTTTGTAGGAAGTAAATCACCAGATATCTTATTGTTTCATTTAGGAAAGTAGTGATATAGATGAAGAGCCAACTTGATGA
ATGTGCTATTCATAAGCTAGAAACTACAGTTTTTCCAAACTAATAAACTGATGAATTCTAAATAAGTTCAGAGATATAGTCATATTTAAAGTTGTCCTAC
AGTTTGCAGATAATTTTTATATTACTATTCTTCACATTAACTTCTGCTTATTTTTAATGGTACTATATGTAGGCCTTATTAAAATTAAGATTGTATGGTT
AAGTAAAGTTAACAAGAAAGCCTGATTTATCTTTAATTCTGTGCTAGGTACTTTTGATTCTACATGAACAATACCCTTTTCAGTTCCCTTCATTCTAATG
TCCTCAACTGTTACCAAATACCCTGTTGACTCCCAAACCTAAGATTTTAGCCTCAACTTCTTTTCTGAACTTCAAATCTTAATTTCCAAGTTATACTTGT
TCTAGGTCCATCTAAATGGTCTACAGAGAACTTCAGTTGAATCATAGCTGGAAACAGAATTTATTTCCTCTATTTGCTTCATTCTGTCCTTCCACTATAT
TCCCTATTT
  • refseq_KRIT1.F7 (forward primer)
  • refseq_KRIT1.R7 (reverse primer)
  • Alternative donor and acceptor

Frame 0

APAQPLAPPPPPP*SPSRLPPAPERLQVQ*KGA
GTAAARPPTRKLFHRQPRGCKGCEPGSDFIATVT
AGWKAKAFEDLGPRSFGRG*GVNGAEVRGEGRT
VKSRFLAFIAFSTCF*PHQKSFISVVQLRISAS
LFSYPSGVHMCLYSFCLQTLSSILRGC*QTCSMD
TKWQLYISPHQS**QPEMPSIFSSDPSLQCVCL
IICKRLLS*SHC*SVVKSNC*IEILRRKRPHPF
HMM*EGLLHEQWEIQKT*KMHMLLLFVQRILPVS
ILGNTELSHMKFCCMKFPLKDRKKRERKFYWKR
NFKATVK*HKAYWIT**KPPNQFLLQTRVSEEN
ELY**KNFLWMERRWAEKHHYLLFHQLSKIILNT
HIPQDAQFFTAYKILCESVVNPVLILLHLQQGC
**PWISG*MNVMHNLTLFQLYSDLLLLSG*KLM
S*ILHMLLNQVRQKTHYIWAIVH*K*RVKC*P*R
KQIPVFTTLCLDQIFSIQIG*IKW**IHTLV*E
LQTTQKSKYLNRKNGREA*AVSQKTRNDSG*MI
FLSTEAPVKEIQNY*AVFSVKDFQSTS*IVTTGH
PFIMHAGMEKLRPLAYC*RKESAIQTF*MDNLV
LLFILLLEEDMLK*YRFS*TTQKRIDI*QTNKE
DLH*IFVKKTNKTTGKKLQNC*RKQLTNHMKKFE
YTEWMGHIVLLN*SMEIIPQCSR*WKECVSLKK
LSNISLYGFVQKTSAFNSNHIINPCNMFVTGQK
YLLN*LIWILKGKHLSFF*EEM*DFPWKLKNRLK
TH*LFLFSLMKPDIIY*RAFIQLLMLS**HWQV
CFCK*SMEIMRVKNTSKVS*MKKI*NPSYLLPN
*KVRHLTGQIAYFMNTRISVQVKVSVKKCITFSA
CSYRIAGKFLLMEQHFSQDRYLQRQAPAIIKSS
LCM*E*I*KDFISSTWKLRLYSSVLSMVVLCGN
WEILILVFRSIAWKIK*AL*YIQNRLVSW*NC**
S*MDS*CPLKEIHEREVTVTQATTFCNAEFFFR
ERFLKILLLAEHGGSPL*FQHFGRLGQADHLKS
EFKTSLANMVKPCLYKNTKISWVWWRAPIILATR
EAKVGDRLNPGGGGCSEPRLHHGTLAWVTQQDS
ISKKKKNYFQQGI*SLVIYMYTITLYRICTYVW
CVIYQLVLYNILISYSNF*EKHKKL*IDSLYNIR
QNSKLYKKLFLVNGKEFGVECDEIKM*LWYNFM
CISKYTERQHDLNKENVFST*TT*HCYLKQFSA
VYKHFSTFF*KS*LKCKSDIQ*CFSKYSS*TPCI
IIT*MPLKNEDFRDPF*TRAFTLWK*HGLVNLN
LVLFFLFCC*NNFRPNKEFRLLKLRNFTKLPGT
QAHTYIDTF*VIIS*Y*KLHLLNTCCIFYELT**
FMYIDFAL*EVNHQISYCFI*ESSDIDEEPT**
MCYS*ARNYSFSKLIN**ILNKFRDIVIFKVVL
QFADNFYITILHINFCLFLMVLYVGLIKIKIVWL
SKVNKKA*FIFNSVLGTFDST*TIPFSVPFILM
SSTVTKYPVDSQT*DFSLNFFSELQILISKLYL
F*VHLNGLQRTSVES*LETEFISSICFILSFHYI
PY

Frame 1

LRLSRWHPHRHHPSLLVACHQPLRDCRSSEKEQ
ERQQPGRRPGSSFTANREAAKGVNPEAIS*PR*
RRGGKLRPLKTWDPVVSGEGEG*MVLRCEEREGQ
*RAGFWLSSLFLHVFSLTRSLSSRWSNSGSQPH
YFLTLLECICAFTVSVCKRCLAY*EDVSKPVPW
TLNGSCTSPLISHSDNQKCPPYFPVIPVFNASVS
*FVNVYYLEVIVNLW*KVIAK*KF*EEKGLILF
T*CRKVCCMSNGKSRKHRRCICCCYSSKEYCQS
QFSGIQS*VI*NFVA*SSH*RTEKKEKESFIGNE
TSRQQ*NNTRHIGLRSRNHQTNFSCKPGYQRKT
SCTNEKISSGWREDGQRSIIIYCSISCQR*Y*I
HIYPRMPNFLLLTRYYASL**IQYSFCYTYSKDV
NSLG*VVR*TSCTISLYSSFIPTFSS*ADKN*C
HKSCICY*IRSDRKLTTYGL*CTRNKE*NVSPR
ESRYLYLQPFVWIRSSVYKSGR*SGNKSILWSRS
SRLLKNPNT*TGKMAEKHEQCHRRQGTTVGR*F
SSPPKRL*RRFRITKPSSQ*KIFSQPVR**PLG
THSLCMLVWKS*GHSHIVRERKVQSKPFKWTT*F
SSSFCCWRRTC*NSTDSPKPPRNG*TYNRPTRK
ISIKYL*RKQTKQLGRSCKIVEGSN*QTI*KSS
NIQNGWVISFC*IEAWK*YHSAADNGRNASLSRN
SAIFHYMDLFRKPQPSTQTIS*TLATCS*LARN
TC*ID*SGSSKGNTSAFSKKRCETSLGS*KTD*
RPTSYSYSL**SQI*FIEGLLYSS*C*ADNIGKS
AFANSLWKL*E*KTQARFPK*RKSKIHRTCYQT
EK*GTSLDKSHTS*IQESQYK*RCQ*RNASPSA
HVLTELLGNSYLWSSIFHRTDIYKGKPQQS*SHP
CVCRSEYKRTSSPQHGN*GFTHQS*VWLFYVAI
GRY*YLFSDP*HGK*NELYSTYKTGWSRGKTVN
EAKWTVNAH*KKFMKEK*LLLKPPHFVMQSFFSV
KDFLKYYFWPSMVAHPCNSSTLGGWGRRIT*SQ
SSRPAWPTW*NPVSTKIQKLAGCGGGRL*S*LL
GRPRWEIA*TQEVEVVVSQDCTTAR*PG*HSKTP
SQKKKKITFNKAYSLL*YICILLHCTESVLMFG
V*YTN*FYIISS*AILIFERNTKSYRLIVCIIL
DKIVSFIKSYFW*MVRNLGWNVMRLKCSFGITSC
VFQNILNVNMI*IKKMYFLLEPHNTVI*NSFLQ
SINISQHFFKSLS*NVNLIYSSVSQSIVHELLA
S*LPRCLLKMKISETHSKQGHSLSGSSMAL*T*I
WFCFFFFAVRIISDPIRNFDY*S*EISQNCLAH
KHTHT*THFK**SLDIRSCIC*IHAVFFMS*LN
SLCILTLLCRK*ITRYLIVSFRKVVI*MKSQLDE
CAIHKLETTVFPN**TDEF*ISSEI*SYLKLSY
SLQIIFILLFFTLTSAYF*WYYM*ALLKLRLYG
*VKLTRKPDLSLILC*VLLILHEQYPFQFPSF*C
PQLLPNTLLTPKPKILASTSFLNFKS*FPSYTC
SRSI*MVYRELQLNHSWKQNLFPLFASFCPSTI
FPI

Frame 2

SGSAAGTPTATTLVS*SPATSP*ETAGPVKRSR
NGSSPAADPEALSPPTARLQRV*TRKRFHSHGN
GGVES*GL*RPGTP*FRERVRGEWC*GARRGKD
SKEQVFGFHRFFYMFLASPEVFHLGGPTQDLSLI
IFLPFWSAYVPLQFLFANAV*HTKRMLANLFHG
H*MAVVHLPSSVIVTTRNALHIFQ*SQSSMRLS
HNL*TFIILKSLLICGEK*LLNRNSEKKKASSFS
HDVGRSVA*AMGNPENIEDAYVAVIRPKNTASL
NSREYRAKSYEILLHEVPIEGQKKKRKKVLLET
KLQGNSEITQGILDYVVETTKPISPANQGIRGKR
VVLMKKFPLDGEKMGREASLFIVPSVVKDNTKY
TYTPGCPIFYCLQDIMRVCSESSTHFATLTARM
LIALDKWLDERHAQSHFIPALFRPSPLERIKTNV
INPAYATESGQTENSLHMGYSALEIKSKMLALE
KADTCIYNPLFGSDLQYTNRVDKVVINPYFGLG
APDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDF
PLHRSACEGDSELLSRLLSERFSVNQLDSDHWA
PIHYACWYGKVEATRILLEKGKCNPNLLNGQLS
SPLHFAAGGGHAEIVQILLNHPETDRHITDQQGR
SPLNICEENKQNNWEEAAKLLKEAINKPYEKVR
IYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQE
TQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEI
LAELTNLDPQRETPQLFLRRDVRLPLEVEKQIE
DPLAILILFDEARYNLLKGFYTAPDAKLITLAS
LLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKL
KSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQR
MFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVI
PVYVGVNIKGLHLLNMETKALLISLKYGCFMWQL
GDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLM
KLNGQLMPTERNS*KRSNCYSSHHIL*CRVFFP
*KIS*NITFGRAWWLTPVIPALWEAGAGGSPEVR
VQDQPGQHGETLSLQKYKN*LGVVAGAYNPSY*
GGQGGRSLKPRRWRL**AKIAPRHASLGDTARL
HLKKKKKLLSTRHIVSCNIYVYYYIVQNLYLCLV
CNIPISFI*YPHKLF*FLRETQKVID**SV*Y*
TK**AL*KVIFGKW*GIWGGM**D*NVALV*LH
VYFKIY*TST*FE*RKCIFYLNHITLLFKTVFCS
L*TFLNIFLKVLVKM*I*YTVVFLKV*FMNSLH
HNYLDAS*K*RFQRPILNKGIHSLEVAWPCELK
FGFVFSFLLLE*FQTQ*GISIIKVEKFHKTAWHT
STHIHRHILSDNLLILEVAFVKYMLYFL*VDLI
VYVY*LCFVGSKSPDILLFHLGK**YR*RANLM
NVLFIS*KLQFFQTNKLMNSK*VQRYSHI*SCPT
VCR*FLYYYSSH*LLLIFNGTICRPY*N*DCMV
K*S*QESLIYL*FCARYF*FYMNNTLFSSLHSN
VLNCYQIPC*LPNLRF*PQLLF*TSNLNFQVILV
LGPSKWSTENFS*IIAGNRIYFLYLLHSVLPLY
SLF

Sequence NM_001013406

GCTCCGGCTCAGCCGCTGGCACCCCCACCGCCACCACCCTAGTCTCCTAGTCGCCTGCCACCAGCCCCTGAGAGACTGCAGGTCCAGTGAAAAGGAGCAG
GAACGGCAGCAGCCCGGCCGCCGACCCGGAAGCTCTTTCACCGCCAACCGCGAGGCTGCAAAGGGTGTGAACCCGGAAGCGATTTCATAGCCACGGTAAC
GGCGGGGTGGAAAGCTAAGGCCTTTGAAGACCTGGGACCCCGTAGTTTCGGGAGAGGGTGAGGGGTGAATGGTGCTGAGGTGCGAGGAGAGGGAAGGACA
GTAAAGAGCAGGTTTTTGGCTTTCATCGCTTTTTCTACATGTTTTTAGCCTCACCAGAAGTCTTTCATCTCGGTGGTCCAACTCAGGATCTCAGCCTCAT
TATTTTCTTACCCTTCTGGAGTGCATATGTGCCTTTACAGTTTCTGTTTGCAAACGCTGTCTAGCATACTAAGAGGATGTTAGCAAACCTGTTCCATGGA
CACTAAATGGCAGTTGTACATCTCCCCTCATCAGTCATAGTGACAACCAGAAATGCCCTCCATATTTTCCAGTGATCCCAGCAATGGGAAATCCAGAAAA
CATAGAAGATGCATATGTTGCTGTTATTCGTCCAAAGAATACTGCCAGTCTCAATTCTCGGGAATACAGAGCTAAGTCATATGAAATTTTGTTGCATGAA
GTTCCCATTGAAGGACAGAAAAAAAAGAGAAAGAAAGTTTTATTGGAAACGAAACTTCAAGGCAACAGTGAAATAACACAAGGCATATTGGATTACGTAG
TAGAAACCACCAAACCAATTTCTCCTGCAAACCAGGGTATCAGAGGAAAACGAGTTGTACTAATGAAAAAATTTCCTCTGGATGGAGAGAAGATGGGCAG
AGAAGCATCATTATTTATTGTTCCATCAGTTGTCAAAGATAATACTAAATACACATATACCCCAGGATGCCCAATTTTTTACTGCTTACAAGATATTATG
CGAGTCTGTAGTGAATCCAGTACTCATTTTGCTACACTTACAGCAAGGATGTTAATAGCCTTGGATAAGTGGTTAGATGAACGTCATGCACAATCTCACT
TTATTCCAGCTTTATTCCGACCTTCTCCTCTTGAGCGGATAAAAACTAATGTCATAAATCCTGCATATGCTACTGAATCAGGTCAGACAGAAAACTCACT
ACATATGGGCTATAGTGCACTAGAAATAAAGAGTAAAATGTTAGCCCTAGAGAAAGCAGATACCTGTATTTACAACCCTTTGTTTGGATCAGATCTTCAG
TATACAAATCGGGTAGATAAAGTGGTAATAAATCCATACTTTGGTCTAGGAGCTCCAGACTACTCAAAAATCCAAATACCTAAACAGGAAAAATGGCAGA
GAAGCATGAGCAGTGTCACAGAAGACAAGTATGGAAAAGTTGAGGCCACTCGCATATTGTTAGAGAAAGGAAAGTGCAATCCAAACCTTTTAAATGGACA
ACTTAGTTCTCCTCTTCATTTTGCTGCTGGAGGAGGACATGCTGAAATAGTACAGATTCTCCTAAACCACCCAGAAACGGATAGACATATAACAGACCAA
CAAGGAAGATCTCCATTAAATATTTGTGAAGAAAACAAACAAAACAACTGGGAAGAAGCTGCAAAATTGTTGAAGGAAGCAATTAACAAACCATATGAAA
AAGTTCGAATATACAGAATGGATGGGTCATATCGTTCTGTTGAATTGAAGCATGGAAATAATACCACAGTGCAGCAGATAATGGAAGGAATGCGTCTCTC
TCAAGAAACTCAGCAATATTTCACTATATGGATTTGTTCAGAAAACCTCAGCCTTCAACTCAAACCATATCATAAACCCTTGCAACATGTTCGTGACTGG
CCAGAAATACTTGCTGAATTGACTAATCTGGATCCTCAAAGGGAAACACCTCAGCTTTTTCTAAGAAGAGATGTGAGACTTCCCTTGGAAGTTGAAAAAC
AGATTGAAGACCCACTAGCTATTCTTATTCTCTTTGATGAAGCCAGATATAATTTATTGAAGGGCTTTTATACAGCTCCTGATGCTAAGCTGATAACATT
GGCAAGTCTGCTTTTGCAAATAGTCTATGGAAATTATGAGAGTAAAAAACACAAGCAAGGTTTCCTAAATGAAGAAAATCTAAAATCCATCGTACCTGTT
ACCAAACTGAAAAGTAAGGCACCTCACTGGACAAATCGCATACTTCATGAATACAAGAATCTCAGTACAAGTGAAGGTGTCAGTAAAGAAATGCATCACC
TTCAGCGCATGTTCTTACAGAATTGCTGGGAAATTCCTACTTATGGAGCAGCATTTTTCACAGGACAGATATTTACAAAGGCAAGCCCCAGCAATCATAA
AGTCATCCCTGTGTATGTAGGAGTGAATATAAAAGGACTTCATCTCCTCAACATGGAAACTAAGGCTTTACTCATCAGTCTTAAGTATGGTTGTTTTATG
TGGCAATTGGGAGATACTGATACTTGTTTTCAGATCCATAGCATGGAAAATAAAATGAGCTTTATAGTACATACAAAACAGGCTGGTCTCGTGGTAAAAC
TGTTAATGAAGCTAAATGGACAGTTAATGCCCACTGAAAGAAATTCATGAAAGAGAAGTAACTGTTACTCAAGCCACCACATTTTGTAATGCAGAGTTTT
TTTTCCGTGAAAGATTTCTTAAAATATTACTTTTGGCCGAGCATGGTGGCTCACCCCTGTAATTCCAGCACTTTGGGAGGCTGGGGCAGGCGGATCACCT
GAAGTCAGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAATTAGCTGGGTGTGGTGGCGGGCGCCTATAATCCTA
GCTACTAGGGAGGCCAAGGTGGGAGATCGCTTAAACCCAGGAGGTGGAGGTTGTAGTGAGCCAAGATTGCACCACGGCACGCTAGCCTGGGTGACACAGC
AAGACTCCATCTCAAAAAAAAAAAAAAATTACTTTCAACAAGGCATATAGTCTCTTGTAATATATATGTATACTATTACATTGTACAGAATCTGTACTTA
TGTTTGGTGTGTAATATACCAATTAGTTTTATATAATATCCTCATAAGCTATTCTAATTTTTGAGAGAAACACAAAAAGTTATAGATTGATAGTCTGTAT
AATATTAGACAAAATAGTAAGCTTTATAAAAAGTTATTTTTGGTAAATGGTAAGGAATTTGGGGTGGAATGTGATGAGATTAAAATGTAGCTTTGGTATA
ACTTCATGTGTATTTCAAAATATACTGAACGTCAACATGATTTGAATAAAGAAAATGTATTTTCTACTTGAACCACATAACACTGTTATTTAAAACAGTT
TTCTGCAGTCTATAAACATTTCTCAACATTTTTTTAAAAGTCTTAGTTAAAATGTAAATCTGATATACAGTAGTGTTTCTCAAAGTATAGTTCATGAACT
CCTTGCATCATAATTACCTAGATGCCTCTTAAAAATGAAGATTTCAGAGACCCATTCTAAACAAGGGCATTCACTCTCTGGAAGTAGCATGGCCTTGTGA
ACTTAAATTTGGTTTTGTTTTTTCTTTTTTGCTGTTAGAATAATTTCAGACCCAATAAGGAATTTCGATTATTAAAGTTGAGAAATTTCACAAAACTGCC
TGGCACACAAGCACACACATACATAGACACATTTTAAGTGATAATCTCTTGATATTAGAAGTTGCATTTGTTAAATACATGCTGTATTTTTTATGAGTTG
ACTTAATAGTTTATGTATATTGACTTTGCTTTGTAGGAAGTAAATCACCAGATATCTTATTGTTTCATTTAGGAAAGTAGTGATATAGATGAAGAGCCAA
CTTGATGAATGTGCTATTCATAAGCTAGAAACTACAGTTTTTCCAAACTAATAAACTGATGAATTCTAAATAAGTTCAGAGATATAGTCATATTTAAAGT
TGTCCTACAGTTTGCAGATAATTTTTATATTACTATTCTTCACATTAACTTCTGCTTATTTTTAATGGTACTATATGTAGGCCTTATTAAAATTAAGATT
GTATGGTTAAGTAAAGTTAACAAGAAAGCCTGATTTATCTTTAATTCTGTGCTAGGTACTTTTGATTCTACATGAACAATACCCTTTTCAGTTCCCTTCA
TTCTAATGTCCTCAACTGTTACCAAATACCCTGTTGACTCCCAAACCTAAGATTTTAGCCTCAACTTCTTTTCTGAACTTCAAATCTTAATTTCCAAGTT
ATACTTGTTCTAGGTCCATCTAAATGGTCTACAGAGAACTTCAGTTGAATCATAGCTGGAAACAGAATTTATTTCCTCTATTTGCTTCATTCTGTCCTTC
CACTATATTCCCTATTT
  • refseq_KRIT1.F7 (forward primer)
  • refseq_KRIT1.R7 (reverse primer)
  • Alternative donor and acceptor

Frame 0

APAQPLAPPPPPP*SPSRLPPAPERLQVQ*KGA
GTAAARPPTRKLFHRQPRGCKGCEPGSDFIATVT
AGWKAKAFEDLGPRSFGRG*GVNGAEVRGEGRT
VKSRFLAFIAFSTCF*PHQKSFISVVQLRISAS
LFSYPSGVHMCLYSFCLQTLSSILRGC*QTCSMD
TKWQLYISPHQS**QPEMPSIFSSDPSNGKSRK
HRRCICCCYSSKEYCQSQFSGIQS*VI*NFVA*
SSH*RTEKKEKESFIGNETSRQQ*NNTRHIGLRS
RNHQTNFSCKPGYQRKTSCTNEKISSGWREDGQ
RSIIIYCSISCQR*Y*IHIYPRMPNFLLLTRYY
ASL**IQYSFCYTYSKDVNSLG*VVR*TSCTISL
YSSFIPTFSS*ADKN*CHKSCICY*IRSDRKLT
TYGL*CTRNKE*NVSPRESRYLYLQPFVWIRSS
VYKSGR*SGNKSILWSRSSRLLKNPNT*TGKMAE
KHEQCHRRQVWKS*GHSHIVRERKVQSKPFKWT
T*FSSSFCCWRRTC*NSTDSPKPPRNG*TYNRP
TRKISIKYL*RKQTKQLGRSCKIVEGSN*QTI*K
SSNIQNGWVISFC*IEAWK*YHSAADNGRNASL
SRNSAIFHYMDLFRKPQPSTQTIS*TLATCS*L
ARNTC*ID*SGSSKGNTSAFSKKRCETSLGS*KT
D*RPTSYSYSL**SQI*FIEGLLYSS*C*ADNI
GKSAFANSLWKL*E*KTQARFPK*RKSKIHRTC
YQTEK*GTSLDKSHTS*IQESQYK*RCQ*RNASP
SAHVLTELLGNSYLWSSIFHRTDIYKGKPQQS*
SHPCVCRSEYKRTSSPQHGN*GFTHQS*VWLFY
VAIGRY*YLFSDP*HGK*NELYSTYKTGWSRGKT
VNEAKWTVNAH*KKFMKEK*LLLKPPHFVMQSF
FSVKDFLKYYFWPSMVAHPCNSSTLGGWGRRIT
*SQSSRPAWPTW*NPVSTKIQKLAGCGGGRL*S*
LLGRPRWEIA*TQEVEVVVSQDCTTAR*PG*HS
KTPSQKKKKITFNKAYSLL*YICILLHCTESVL
MFGV*YTN*FYIISS*AILIFERNTKSYRLIVCI
ILDKIVSFIKSYFW*MVRNLGWNVMRLKCSFGI
TSCVFQNILNVNMI*IKKMYFLLEPHNTVI*NS
FLQSINISQHFFKSLS*NVNLIYSSVSQSIVHEL
LAS*LPRCLLKMKISETHSKQGHSLSGSSMAL*
T*IWFCFFFFAVRIISDPIRNFDY*S*EISQNC
LAHKHTHT*THFK**SLDIRSCIC*IHAVFFMS*
LNSLCILTLLCRK*ITRYLIVSFRKVVI*MKSQ
LDECAIHKLETTVFPN**TDEF*ISSEI*SYLK
LSYSLQIIFILLFFTLTSAYF*WYYM*ALLKLRL
YG*VKLTRKPDLSLILC*VLLILHEQYPFQFPS
F*CPQLLPNTLLTPKPKILASTSFLNFKS*FPS
YTCSRSI*MVYRELQLNHSWKQNLFPLFASFCPS
TIFPI

Frame 1

LRLSRWHPHRHHPSLLVACHQPLRDCRSSEKEQ
ERQQPGRRPGSSFTANREAAKGVNPEAIS*PR*
RRGGKLRPLKTWDPVVSGEGEG*MVLRCEEREGQ
*RAGFWLSSLFLHVFSLTRSLSSRWSNSGSQPH
YFLTLLECICAFTVSVCKRCLAY*EDVSKPVPW
TLNGSCTSPLISHSDNQKCPPYFPVIPAMGNPEN
IEDAYVAVIRPKNTASLNSREYRAKSYEILLHE
VPIEGQKKKRKKVLLETKLQGNSEITQGILDYV
VETTKPISPANQGIRGKRVVLMKKFPLDGEKMGR
EASLFIVPSVVKDNTKYTYTPGCPIFYCLQDIM
RVCSESSTHFATLTARMLIALDKWLDERHAQSH
FIPALFRPSPLERIKTNVINPAYATESGQTENSL
HMGYSALEIKSKMLALEKADTCIYNPLFGSDLQ
YTNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQ
RSMSSVTEDKYGKVEATRILLEKGKCNPNLLNGQ
LSSPLHFAAGGGHAEIVQILLNHPETDRHITDQ
QGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLS
QETQQYFTIWICSENLSLQLKPYHKPLQHVRDW
PEILAELTNLDPQRETPQLFLRRDVRLPLEVEK
QIEDPLAILILFDEARYNLLKGFYTAPDAKLITL
ASLLLQIVYGNYESKKHKQGFLNEENLKSIVPV
TKLKSKAPHWTNRILHEYKNLSTSEGVSKEMHH
LQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHK
VIPVYVGVNIKGLHLLNMETKALLISLKYGCFM
WQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
LLMKLNGQLMPTERNS*KRSNCYSSHHIL*CRVF
FP*KIS*NITFGRAWWLTPVIPALWEAGAGGSP
EVRVQDQPGQHGETLSLQKYKN*LGVVAGAYNP
SY*GGQGGRSLKPRRWRL**AKIAPRHASLGDTA
RLHLKKKKKLLSTRHIVSCNIYVYYYIVQNLYL
CLVCNIPISFI*YPHKLF*FLRETQKVID**SV
*Y*TK**AL*KVIFGKW*GIWGGM**D*NVALV*
LHVYFKIY*TST*FE*RKCIFYLNHITLLFKTV
FCSL*TFLNIFLKVLVKM*I*YTVVFLKV*FMN
SLHHNYLDAS*K*RFQRPILNKGIHSLEVAWPCE
LKFGFVFSFLLLE*FQTQ*GISIIKVEKFHKTA
WHTSTHIHRHILSDNLLILEVAFVKYMLYFL*V
DLIVYVY*LCFVGSKSPDILLFHLGK**YR*RAN
LMNVLFIS*KLQFFQTNKLMNSK*VQRYSHI*S
CPTVCR*FLYYYSSH*LLLIFNGTICRPY*N*D
CMVK*S*QESLIYL*FCARYF*FYMNNTLFSSLH
SNVLNCYQIPC*LPNLRF*PQLLF*TSNLNFQV
ILVLGPSKWSTENFS*IIAGNRIYFLYLLHSVL
PLYSLF

Frame 2

SGSAAGTPTATTLVS*SPATSP*ETAGPVKRSR
NGSSPAADPEALSPPTARLQRV*TRKRFHSHGN
GGVES*GL*RPGTP*FRERVRGEWC*GARRGKD
SKEQVFGFHRFFYMFLASPEVFHLGGPTQDLSLI
IFLPFWSAYVPLQFLFANAV*HTKRMLANLFHG
H*MAVVHLPSSVIVTTRNALHIFQ*SQQWEIQK
T*KMHMLLLFVQRILPVSILGNTELSHMKFCCMK
FPLKDRKKRERKFYWKRNFKATVK*HKAYWIT*
*KPPNQFLLQTRVSEENELY**KNFLWMERRWA
EKHHYLLFHQLSKIILNTHIPQDAQFFTAYKILC
ESVVNPVLILLHLQQGC**PWISG*MNVMHNLT
LFQLYSDLLLLSG*KLMS*ILHMLLNQVRQKTH
YIWAIVH*K*RVKC*P*RKQIPVFTTLCLDQIFS
IQIG*IKW**IHTLV*ELQTTQKSKYLNRKNGR
EA*AVSQKTSMEKLRPLAYC*RKESAIQTF*MD
NLVLLFILLLEEDMLK*YRFS*TTQKRIDI*QTN
KEDLH*IFVKKTNKTTGKKLQNC*RKQLTNHMK
KFEYTEWMGHIVLLN*SMEIIPQCSR*WKECVS
LKKLSNISLYGFVQKTSAFNSNHIINPCNMFVTG
QKYLLN*LIWILKGKHLSFF*EEM*DFPWKLKN
RLKTH*LFLFSLMKPDIIY*RAFIQLLMLS**H
WQVCFCK*SMEIMRVKNTSKVS*MKKI*NPSYLL
PN*KVRHLTGQIAYFMNTRISVQVKVSVKKCIT
FSACSYRIAGKFLLMEQHFSQDRYLQRQAPAII
KSSLCM*E*I*KDFISSTWKLRLYSSVLSMVVLC
GNWEILILVFRSIAWKIK*AL*YIQNRLVSW*N
C**S*MDS*CPLKEIHEREVTVTQATTFCNAEF
FFRERFLKILLLAEHGGSPL*FQHFGRLGQADHL
KSEFKTSLANMVKPCLYKNTKISWVWWRAPIIL
ATREAKVGDRLNPGGGGCSEPRLHHGTLAWVTQ
QDSISKKKKNYFQQGI*SLVIYMYTITLYRICTY
VWCVIYQLVLYNILISYSNF*EKHKKL*IDSLY
NIRQNSKLYKKLFLVNGKEFGVECDEIKM*LWY
NFMCISKYTERQHDLNKENVFST*TT*HCYLKQF
SAVYKHFSTFF*KS*LKCKSDIQ*CFSKYSS*T
PCIIIT*MPLKNEDFRDPF*TRAFTLWK*HGLV
NLNLVLFFLFCC*NNFRPNKEFRLLKLRNFTKLP
GTQAHTYIDTF*VIIS*Y*KLHLLNTCCIFYEL
T**FMYIDFAL*EVNHQISYCFI*ESSDIDEEP
T**MCYS*ARNYSFSKLIN**ILNKFRDIVIFKV
VLQFADNFYITILHINFCLFLMVLYVGLIKIKI
VWLSKVNKKA*FIFNSVLGTFDST*TIPFSVPF
ILMSSTVTKYPVDSQT*DFSLNFFSELQILISKL
YLF*VHLNGLQRTSVES*LETEFISSICFILSF
HYIPY

Sequence NM_194455

GCTCCGGCTCAGCCGCTGGCACCCCCACCGCCACCACCCTAGTCTCCTAGTCGCCTGCCACCAGCCCCTGAGAGACTGCAGGTCCAGTGAAAAGGAGCAG
GAACGGCAGCAGCCCGGCCGCCGACCCGGAAGCTCTTTCACCGCCAACCGCGAGGCTGCAAAGGGTGTGAACCCGGAAGCGATTTCATAGCCACGGTAAC
GGCGGGGTGGAAAGCTAAGGCCTTTGAAGACCTGGGACCCCGTAGTTTCGGGAGAGGGTGAGGGGTGAATGGTGCTGAGGTGCGAGGAGAGGGAAGGACA
GTAAAGAGCAGGTGGGCAGGAGGGTCTCCGACTCCAGAGACCTGAGCTTTTGGGGCGCGGGTGGGAGCGCGGGGGAACCCTCAAGACGGCTTTCTTTTGG
CGACTGAGGGTTTTTCTGCCACAGGAAGCTGGGCCGGGCTGCTGTGCCTGGGAGGAGGGAAGGAGGAATGAGAAAGCGGTGACGGTCCCTGCCCCCCCTC
GCCAGGTGACTGTCCCACCCATTTAGTTGAATGTAGCGGCCAGAGAGGCACTCGCGGCAGCCCGTACGGGTGGGACCTCTCGGTGTCCTTCGGGAAACAG
GAGGAGCAAGTTCGACTCCAGCGAGGGAAAACGGAGCCTCACCAGAAGTCTTTCATCTCGGTGGTCCAACTCAGGATCTCAGCCTCATTATTTTCTTACC
CTTCTGGAGTGCATATGTGCCTTTACAGTTTCTGTTTGCAAACGCTGTCTAGCATACTAAGAGGATGTTAGCAAACCTGTTCCATGGACACTAAATGGCA
GTTGTACATCTCCCCTCATCAGTCATAGTGACAACCAGAAATGCCCTCCATATTTTCCAGTGATCCCAGTCTTCAATGCGTCTGTCTCATAATTTGTAAA
CGTTTATTATCTTGAAGTCATTGTTAATCTGTGGTGAAAAGTAATTGCTAAATAGAAATTCTGAGAAGAAAAAGGCCTCATCCTTTTCACATGATGTAGG
AAGGTCTGTTGCATGAGCAATGGGAAATCCAGAAAACATAGAAGATGCATATGTTGCTGTTATTCGTCCAAAGAATACTGCCAGTCTCAATTCTCGGGAA
TACAGAGCTAAGTCATATGAAATTTTGTTGCATGAAGTTCCCATTGAAGGACAGAAAAAAAAGAGAAAGAAAGTTTTATTGGAAACGAAACTTCAAGGCA
ACAGTGAAATAACACAAGGCATATTGGATTACGTAGTAGAAACCACCAAACCAATTTCTCCTGCAAACCAGGGTATCAGAGGAAAACGAGTTGTACTAAT
GAAAAAATTTCCTCTGGATGGAGAGAAGATGGGCAGAGAAGCATCATTATTTATTGTTCCATCAGTTGTCAAAGATAATACTAAATACACATATACCCCA
GGATGCCCAATTTTTTACTGCTTACAAGATATTATGCGAGTCTGTAGTGAATCCAGTACTCATTTTGCTACACTTACAGCAAGGATGTTAATAGCCTTGG
ATAAGTGGTTAGATGAACGTCATGCACAATCTCACTTTATTCCAGCTTTATTCCGACCTTCTCCTCTTGAGCGGATAAAAACTAATGTCATAAATCCTGC
ATATGCTACTGAATCAGGTCAGACAGAAAACTCACTACATATGGGCTATAGTGCACTAGAAATAAAGAGTAAAATGTTAGCCCTAGAGAAAGCAGATACC
TGTATTTACAACCCTTTGTTTGGATCAGATCTTCAGTATACAAATCGGGTAGATAAAGTGGTAATAAATCCATACTTTGGTCTAGGAGCTCCAGACTACT
CAAAAATCCAAATACCTAAACAGGAAAAATGGCAGAGAAGCATGAGCAGTGTCACAGAAGACAAGGAACGACAGTGGGTAGATGATTTTCCTCTCCACCG
AAGCGCCTGTGAAGGAGATTCAGAATTACTAAGCCGTCTTCTCAGTGAAAGATTTTCAGTCAACCAGTTAGATAGTGACCACTGGGCACCCATTCATTAT
GCATGCTGGTATGGAAAAGTTGAGGCCACTCGCATATTGTTAGAGAAAGGAAAGTGCAATCCAAACCTTTTAAATGGACAACTTAGTTCTCCTCTTCATT
TTGCTGCTGGAGGAGGACATGCTGAAATAGTACAGATTCTCCTAAACCACCCAGAAACGGATAGACATATAACAGACCAACAAGGAAGATCTCCATTAAA
TATTTGTGAAGAAAACAAACAAAACAACTGGGAAGAAGCTGCAAAATTGTTGAAGGAAGCAATTAACAAACCATATGAAAAAGTTCGAATATACAGAATG
GATGGGTCATATCGTTCTGTTGAATTGAAGCATGGAAATAATACCACAGTGCAGCAGATAATGGAAGGAATGCGTCTCTCTCAAGAAACTCAGCAATATT
TCACTATATGGATTTGTTCAGAAAACCTCAGCCTTCAACTCAAACCATATCATAAACCCTTGCAACATGTTCGTGACTGGCCAGAAATACTTGCTGAATT
GACTAATCTGGATCCTCAAAGGGAAACACCTCAGCTTTTTCTAAGAAGAGATGTGAGACTTCCCTTGGAAGTTGAAAAACAGATTGAAGACCCACTAGCT
ATTCTTATTCTCTTTGATGAAGCCAGATATAATTTATTGAAGGGCTTTTATACAGCTCCTGATGCTAAGCTGATAACATTGGCAAGTCTGCTTTTGCAAA
TAGTCTATGGAAATTATGAGAGTAAAAAACACAAGCAAGGTTTCCTAAATGAAGAAAATCTAAAATCCATCGTACCTGTTACCAAACTGAAAAGTAAGGC
ACCTCACTGGACAAATCGCATACTTCATGAATACAAGAATCTCAGTACAAGTGAAGGTGTCAGTAAAGAAATGCATCACCTTCAGCGCATGTTCTTACAG
AATTGCTGGGAAATTCCTACTTATGGAGCAGCATTTTTCACAGGACAGATATTTACAAAGGCAAGCCCCAGCAATCATAAAGTCATCCCTGTGTATGTAG
GAGTGAATATAAAAGGACTTCATCTCCTCAACATGGAAACTAAGGCTTTACTCATCAGTCTTAAGTATGGTTGTTTTATGTGGCAATTGGGAGATACTGA
TACTTGTTTTCAGATCCATAGCATGGAAAATAAAATGAGCTTTATAGTACATACAAAACAGGCTGGTCTCGTGGTAAAACTGTTAATGAAGCTAAATGGA
CAGTTAATGCCCACTGAAAGAAATTCATGAAAGAGAAGTAACTGTTACTCAAGCCACCACATTTTGTAATGCAGAGTTTTTTTTCCGTGAAAGATTTCTT
AAAATATTACTTTTGGCCGAGCATGGTGGCTCACCCCTGTAATTCCAGCACTTTGGGAGGCTGGGGCAGGCGGATCACCTGAAGTCAGAGTTCAAGACCA
GCCTGGCCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAATTAGCTGGGTGTGGTGGCGGGCGCCTATAATCCTAGCTACTAGGGAGGCCAAGGT
GGGAGATCGCTTAAACCCAGGAGGTGGAGGTTGTAGTGAGCCAAGATTGCACCACGGCACGCTAGCCTGGGTGACACAGCAAGACTCCATCTCAAAAAAA
AAAAAAAATTACTTTCAACAAGGCATATAGTCTCTTGTAATATATATGTATACTATTACATTGTACAGAATCTGTACTTATGTTTGGTGTGTAATATACC
AATTAGTTTTATATAATATCCTCATAAGCTATTCTAATTTTTGAGAGAAACACAAAAAGTTATAGATTGATAGTCTGTATAATATTAGACAAAATAGTAA
GCTTTATAAAAAGTTATTTTTGGTAAATGGTAAGGAATTTGGGGTGGAATGTGATGAGATTAAAATGTAGCTTTGGTATAACTTCATGTGTATTTCAAAA
TATACTGAACGTCAACATGATTTGAATAAAGAAAATGTATTTTCTACTTGAACCACATAACACTGTTATTTAAAACAGTTTTCTGCAGTCTATAAACATT
TCTCAACATTTTTTTAAAAGTCTTAGTTAAAATGTAAATCTGATATACAGTAGTGTTTCTCAAAGTATAGTTCATGAACTCCTTGCATCATAATTACCTA
GATGCCTCTTAAAAATGAAGATTTCAGAGACCCATTCTAAACAAGGGCATTCACTCTCTGGAAGTAGCATGGCCTTGTGAACTTAAATTTGGTTTTGTTT
TTTCTTTTTTGCTGTTAGAATAATTTCAGACCCAATAAGGAATTTCGATTATTAAAGTTGAGAAATTTCACAAAACTGCCTGGCACACAAGCACACACAT
ACATAGACACATTTTAAGTGATAATCTCTTGATATTAGAAGTTGCATTTGTTAAATACATGCTGTATTTTTTATGAGTTGACTTAATAGTTTATGTATAT
TGACTTTGCTTTGTAGGAAGTAAATCACCAGATATCTTATTGTTTCATTTAGGAAAGTAGTGATATAGATGAAGAGCCAACTTGATGAATGTGCTATTCA
TAAGCTAGAAACTACAGTTTTTCCAAACTAATAAACTGATGAATTCTAAATAAGTTCAGAGATATAGTCATATTTAAAGTTGTCCTACAGTTTGCAGATA
ATTTTTATATTACTATTCTTCACATTAACTTCTGCTTATTTTTAATGGTACTATATGTAGGCCTTATTAAAATTAAGATTGTATGGTTAAGTAAAGTTAA
CAAGAAAGCCTGATTTATCTTTAATTCTGTGCTAGGTACTTTTGATTCTACATGAACAATACCCTTTTCAGTTCCCTTCATTCTAATGTCCTCAACTGTT
ACCAAATACCCTGTTGACTCCCAAACCTAAGATTTTAGCCTCAACTTCTTTTCTGAACTTCAAATCTTAATTTCCAAGTTATACTTGTTCTAGGTCCATC
TAAATGGTCTACAGAGAACTTCAGTTGAATCATAGCTGGAAACAGAATTTATTTCCTCTATTTGCTTCATTCTGTCCTTCCACTATATTCCCTATTT
  • refseq_KRIT1.F7 (forward primer)
  • refseq_KRIT1.R7 (reverse primer)
  • Alternative donor and acceptor

Frame 0

APAQPLAPPPPPP*SPSRLPPAPERLQVQ*KGA
GTAAARPPTRKLFHRQPRGCKGCEPGSDFIATVT
AGWKAKAFEDLGPRSFGRG*GVNGAEVRGEGRT
VKSRWAGGSPTPET*AFGARVGARGNPQDGFLL
ATEGFSATGSWAGLLCLGGGKEE*ESGDGPCPPS
PGDCPTHLVECSGQRGTRGSPYGWDLSVSFGKQ
EEQVRLQRGKTEPHQKSFISVVQLRISASLFSY
PSGVHMCLYSFCLQTLSSILRGC*QTCSMDTKWQ
LYISPHQS**QPEMPSIFSSDPSLQCVCLIICK
RLLS*SHC*SVVKSNC*IEILRRKRPHPFHMM*
EGLLHEQWEIQKT*KMHMLLLFVQRILPVSILGN
TELSHMKFCCMKFPLKDRKKRERKFYWKRNFKA
TVK*HKAYWIT**KPPNQFLLQTRVSEENELY*
*KNFLWMERRWAEKHHYLLFHQLSKIILNTHIPQ
DAQFFTAYKILCESVVNPVLILLHLQQGC**PW
ISG*MNVMHNLTLFQLYSDLLLLSG*KLMS*IL
HMLLNQVRQKTHYIWAIVH*K*RVKC*P*RKQIP
VFTTLCLDQIFSIQIG*IKW**IHTLV*ELQTT
QKSKYLNRKNGREA*AVSQKTRNDSG*MIFLST
EAPVKEIQNY*AVFSVKDFQSTS*IVTTGHPFIM
HAGMEKLRPLAYC*RKESAIQTF*MDNLVLLFI
LLLEEDMLK*YRFS*TTQKRIDI*QTNKEDLH*
IFVKKTNKTTGKKLQNC*RKQLTNHMKKFEYTEW
MGHIVLLN*SMEIIPQCSR*WKECVSLKKLSNI
SLYGFVQKTSAFNSNHIINPCNMFVTGQKYLLN
*LIWILKGKHLSFF*EEM*DFPWKLKNRLKTH*L
FLFSLMKPDIIY*RAFIQLLMLS**HWQVCFCK
*SMEIMRVKNTSKVS*MKKI*NPSYLLPN*KVR
HLTGQIAYFMNTRISVQVKVSVKKCITFSACSYR
IAGKFLLMEQHFSQDRYLQRQAPAIIKSSLCM*
E*I*KDFISSTWKLRLYSSVLSMVVLCGNWEIL
ILVFRSIAWKIK*AL*YIQNRLVSW*NC**S*MD
S*CPLKEIHEREVTVTQATTFCNAEFFFRERFL
KILLLAEHGGSPL*FQHFGRLGQADHLKSEFKT
SLANMVKPCLYKNTKISWVWWRAPIILATREAKV
GDRLNPGGGGCSEPRLHHGTLAWVTQQDSISKK
KKNYFQQGI*SLVIYMYTITLYRICTYVWCVIY
QLVLYNILISYSNF*EKHKKL*IDSLYNIRQNSK
LYKKLFLVNGKEFGVECDEIKM*LWYNFMCISK
YTERQHDLNKENVFST*TT*HCYLKQFSAVYKH
FSTFF*KS*LKCKSDIQ*CFSKYSS*TPCIIIT*
MPLKNEDFRDPF*TRAFTLWK*HGLVNLNLVLF
FLFCC*NNFRPNKEFRLLKLRNFTKLPGTQAHT
YIDTF*VIIS*Y*KLHLLNTCCIFYELT**FMYI
DFAL*EVNHQISYCFI*ESSDIDEEPT**MCYS
*ARNYSFSKLIN**ILNKFRDIVIFKVVLQFAD
NFYITILHINFCLFLMVLYVGLIKIKIVWLSKVN
KKA*FIFNSVLGTFDST*TIPFSVPFILMSSTV
TKYPVDSQT*DFSLNFFSELQILISKLYLF*VH
LNGLQRTSVES*LETEFISSICFILSFHYIPY

Frame 1

LRLSRWHPHRHHPSLLVACHQPLRDCRSSEKEQ
ERQQPGRRPGSSFTANREAAKGVNPEAIS*PR*
RRGGKLRPLKTWDPVVSGEGEG*MVLRCEEREGQ
*RAGGQEGLRLQRPELLGRGWERGGTLKTAFFW
RLRVFLPQEAGPGCCAWEEGRRNEKAVTVPAPP
RQVTVPPI*LNVAAREALAAARTGGTSRCPSGNR
RSKFDSSEGKRSLTRSLSSRWSNSGSQPHYFLT
LLECICAFTVSVCKRCLAY*EDVSKPVPWTLNG
SCTSPLISHSDNQKCPPYFPVIPVFNASVS*FVN
VYYLEVIVNLW*KVIAK*KF*EEKGLILFT*CR
KVCCMSNGKSRKHRRCICCCYSSKEYCQSQFSG
IQS*VI*NFVA*SSH*RTEKKEKESFIGNETSRQ
Q*NNTRHIGLRSRNHQTNFSCKPGYQRKTSCTN
EKISSGWREDGQRSIIIYCSISCQR*Y*IHIYP
RMPNFLLLTRYYASL**IQYSFCYTYSKDVNSLG
*VVR*TSCTISLYSSFIPTFSS*ADKN*CHKSC
ICY*IRSDRKLTTYGL*CTRNKE*NVSPRESRY
LYLQPFVWIRSSVYKSGR*SGNKSILWSRSSRLL
KNPNT*TGKMAEKHEQCHRRQGTTVGR*FSSPP
KRL*RRFRITKPSSQ*KIFSQPVR**PLGTHSL
CMLVWKS*GHSHIVRERKVQSKPFKWTT*FSSSF
CCWRRTC*NSTDSPKPPRNG*TYNRPTRKISIK
YL*RKQTKQLGRSCKIVEGSN*QTI*KSSNIQN
GWVISFC*IEAWK*YHSAADNGRNASLSRNSAIF
HYMDLFRKPQPSTQTIS*TLATCS*LARNTC*I
D*SGSSKGNTSAFSKKRCETSLGS*KTD*RPTS
YSYSL**SQI*FIEGLLYSS*C*ADNIGKSAFAN
SLWKL*E*KTQARFPK*RKSKIHRTCYQTEK*G
TSLDKSHTS*IQESQYK*RCQ*RNASPSAHVLT
ELLGNSYLWSSIFHRTDIYKGKPQQS*SHPCVCR
SEYKRTSSPQHGN*GFTHQS*VWLFYVAIGRY*
YLFSDP*HGK*NELYSTYKTGWSRGKTVNEAKW
TVNAH*KKFMKEK*LLLKPPHFVMQSFFSVKDFL
KYYFWPSMVAHPCNSSTLGGWGRRIT*SQSSRP
AWPTW*NPVSTKIQKLAGCGGGRL*S*LLGRPR
WEIA*TQEVEVVVSQDCTTAR*PG*HSKTPSQKK
KKITFNKAYSLL*YICILLHCTESVLMFGV*YT
N*FYIISS*AILIFERNTKSYRLIVCIILDKIV
SFIKSYFW*MVRNLGWNVMRLKCSFGITSCVFQN
ILNVNMI*IKKMYFLLEPHNTVI*NSFLQSINI
SQHFFKSLS*NVNLIYSSVSQSIVHELLAS*LP
RCLLKMKISETHSKQGHSLSGSSMAL*T*IWFCF
FFFAVRIISDPIRNFDY*S*EISQNCLAHKHTH
T*THFK**SLDIRSCIC*IHAVFFMS*LNSLCI
LTLLCRK*ITRYLIVSFRKVVI*MKSQLDECAIH
KLETTVFPN**TDEF*ISSEI*SYLKLSYSLQI
IFILLFFTLTSAYF*WYYM*ALLKLRLYG*VKL
TRKPDLSLILC*VLLILHEQYPFQFPSF*CPQLL
PNTLLTPKPKILASTSFLNFKS*FPSYTCSRSI
*MVYRELQLNHSWKQNLFPLFASFCPSTIFPI

Frame 2

SGSAAGTPTATTLVS*SPATSP*ETAGPVKRSR
NGSSPAADPEALSPPTARLQRV*TRKRFHSHGN
GGVES*GL*RPGTP*FRERVRGEWC*GARRGKD
SKEQVGRRVSDSRDLSFWGAGGSAGEPSRRLSFG
D*GFFCHRKLGRAAVPGRREGGMRKR*RSLPPL
AR*LSHPFS*M*RPERHSRQPVRVGPLGVLRET
GGASSTPARENGASPEVFHLGGPTQDLSLIIFLP
FWSAYVPLQFLFANAV*HTKRMLANLFHGH*MA
VVHLPSSVIVTTRNALHIFQ*SQSSMRLSHNL*
TFIILKSLLICGEK*LLNRNSEKKKASSFSHDVG
RSVA*AMGNPENIEDAYVAVIRPKNTASLNSRE
YRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
NSEITQGILDYVVETTKPISPANQGIRGKRVVLM
KKFPLDGEKMGREASLFIVPSVVKDNTKYTYTP
GCPIFYCLQDIMRVCSESSTHFATLTARMLIAL
DKWLDERHAQSHFIPALFRPSPLERIKTNVINPA
YATESGQTENSLHMGYSALEIKSKMLALEKADT
CIYNPLFGSDLQYTNRVDKVVINPYFGLGAPDY
SKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHR
SACEGDSELLSRLLSERFSVNQLDSDHWAPIHY
ACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN
ICEENKQNNWEEAAKLLKEAINKPYEKVRIYRM
DGSYRSVELKHGNNTTVQQIMEGMRLSQETQQY
FTIWICSENLSLQLKPYHKPLQHVRDWPEILAEL
TNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLA
ILILFDEARYNLLKGFYTAPDAKLITLASLLLQ
IVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKA
PHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQ
NCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTD
TCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNG
QLMPTERNS*KRSNCYSSHHIL*CRVFFP*KIS
*NITFGRAWWLTPVIPALWEAGAGGSPEVRVQDQ
PGQHGETLSLQKYKN*LGVVAGAYNPSY*GGQG
GRSLKPRRWRL**AKIAPRHASLGDTARLHLKK
KKKLLSTRHIVSCNIYVYYYIVQNLYLCLVCNIP
ISFI*YPHKLF*FLRETQKVID**SV*Y*TK**
AL*KVIFGKW*GIWGGM**D*NVALV*LHVYFK
IY*TST*FE*RKCIFYLNHITLLFKTVFCSL*TF
LNIFLKVLVKM*I*YTVVFLKV*FMNSLHHNYL
DAS*K*RFQRPILNKGIHSLEVAWPCELKFGFV
FSFLLLE*FQTQ*GISIIKVEKFHKTAWHTSTHI
HRHILSDNLLILEVAFVKYMLYFL*VDLIVYVY
*LCFVGSKSPDILLFHLGK**YR*RANLMNVLF
IS*KLQFFQTNKLMNSK*VQRYSHI*SCPTVCR*
FLYYYSSH*LLLIFNGTICRPY*N*DCMVK*S*
QESLIYL*FCARYF*FYMNNTLFSSLHSNVLNC
YQIPC*LPNLRF*PQLLF*TSNLNFQVILVLGPS
KWSTENFS*IIAGNRIYFLYLLHSVLPLYSLF

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