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Sequences

Sequence XM_929312

GTCCCCGGCCGGCCGGAGCGGCGGCGGTGGCGGCGCGAGGCGGCATGAGGGAGCCGCTCGTGCTGGGTCCTGCCACCACCATGGTTCCAGTGGTTGAGCT
TTGCTGAAGCCCAGGCATCATGTACAGTGTAGAAGACCTCCTGATCTCTCATGGATACAAGCTGTCAAGAGACCCCCCAGCATCACGCGAGGATAACCCC
AAGGGGCGCCAGGCAGCGAGGACTGGGACACGAGCAGGCCAGGGCCTGCAGAACGGGCATGAGGATGGCCCTGCGGCCCTCGCACATCGTAAGACGTCCG
CGGGGAAAGGACATGTGAGTGACTCCGAAAGCCGCCGCAGCACACCGAGAGGCCACGGGGAGCCCCAGAGCACTTCTGCTTCCAGAACCTCGGAGGCGGG
GTTTTGTAATCAACCCCCCTCAGCATGGTCCTCTCATCCCCCGACTGGTAACGACCAAGCCTACCGGAGAAGAGGACGGCAAGAAGCCAGGAGCCAGAAG
CCGAGGGAGCACGAAAACCTGGAGGCCAGAGGAATGGCCCAAGCCCACAGCCTGCCTGTCCACGTGAGGGAGGGTCCATGGGAAGTTGGAGGAAGGTCAG
AGCATGTGATGAAGAAGCCAGTTTGGGAAGAAGAATTGCGAATGTCAGGTCCTGCCAAGTGGCAGAACGTCAGCCTGGAAAGCTGGAACCAGCCAAGGAA
ATTAGGGAGGCAGATGTCTGATGGAGATGGGGAGAGACTGTTTCAAGACCTGTACCCATTCATTCAAGGAGAACATGTGTTGAATTCTCAAAACAAAGGG
AAGTCTCGCTCACTGCCTAGAGTTCTTTCCCCCGAGAGCCTGAGTTGCACGGAAATTCCCATTCCATTAAATGAAAGACATTCACCTAAAATGCCACCGT
ATCCTCCCACTTGCGCACCAAATTTGGACTCCACGAGGAATTCTGAGAAGAGTGGCTGCTCAGCCCCATTTCCCCGGCCTAAGTTTGGGAGGCCCCTCAA
GCCCCCATCTTACAGCTCGCACCAGCAGTCTAGGGGAGGAGCGGACAGCAGTGACTCTCAGGACAGCCAGCAGATGGACGCCTATGTCCCCAGGCATGAG
CTCTGCCTGTCAGACCCTGGATTGGAACCTCCAGTGTACGTGCCTCCGCCCTCATACAGATCGCCCCCGCAGAACATCCCAAACCCCTACTTGGAAGACA
CGGTGCCCATAAATGTGTGTGGCGGTCACAGTCAACAGCAGTCTCCGACCGAGAAGGCTGGGGCCAGCGGTCAGCCTCCTTCAGGCCCCCCTGGAACTGG
GAATGAGTATGGTGTGAGCCCCCGCTTGCCTCAGGGGCTCCCCGCACATCCCCGACCTGTCACTGCCTATGACGGCTTCGTTCAGTACATTCCCTTTGAT
GATCCACGGTTACGACATTTTAAACTAGCTCAGCCCCAGGGTTTCTGTGAAGACATAAAGCTTGACGATAAATCATATAACTCCAGTCCTGTCACTGCTC
AAGAGCCGGCTCATGGAGGAATGCAGCCTGATGGTGCCATTTGGAATCCACAGAGCTTAATACCCCCGTCGGGGGATGAGAGAGGCCTGGTCTTGGCCGA
TTCCAGCCCCCGGTGGCTGTGGGGCCAGCCCCCCGGGGATGGGGAAAACAGTGGCCTCCCCAACCAGAGAGACCGCTGTGTGGCAAGGGGACAGTGGCCT
GATGTGAGAGGCAGCCAGCACGGGCACACTGGAAGACAAGTTTCCTCCCCTTACTCACAGGGCGAGAGCACCTGCGAAACTCAAACCAAGCTCAAAAAGT
TCCAAACTGGGACTCGGACCAAGAAAAGTTCAAAGAAAAAAATGAACGAGACTATATTTTGCTTGGTTTCTATCCCAGTGAAATCAGAATCACATCTGCC
AGATAGAGATATGGACAACAATGACTTAAAGCCCAGTGCTGATCAAAAGAATGGGTCTGATAAGAGCCCGGCTCTGCAAGAACAGAGTCTGCTGAGCATG
TCTTCCACCGACCTGGAGCTGCAGGCCCTCACAGGAAGCATGGGTGGGAGAACGGAGTTCCAAAAACAAGATCTAGGGGAACCAGAAGAAGACAGACAAA
CAAATGACCTCAGTTTCATCCACCTTACAAAGCACAGAGAACTCAAGCATTCTGGCTCTTGGCCAGGGCACCGGTACAGAGATCAGCAAACACAAACCAG
TTTCTCCGAGGAGCCCCAAAGTTCGCAGCTGCTCCCTGGTGCAAAGCTGGGAGGGCCGAGTCGTGCAGCATTGAGTCCAAAATGTTCAGACCCTGCTGCC
TCCGAAGCTCAGACGCACACAGCATTCCCTACCGGTGATCACAAACAGAGGCCAAGTGCCCGTAACCTGAAAGGTCACAGGTCCCTCAGCCCATCCAGCA
ACAGTGCGTTCTCAAGGACTTCCTTGTCCGTGGACCAGGCACCGACGCCAAAAGCAGGCCGAAGTCAGCCCTGCGTGGATGTCCACGGGCTTGGAGCCCA
CCCTGGGCCTAAGCGGGAGGTGGTGAAGGGGGAGCCCACGGGCCCTTGCAACAGTAAACAACTCTTTGGGCAGTTTCTCCTGAAACCGGTCAGCCGTCGT
CCCTGGGATTTGATCAGTCAGTTAGAAAGTTTTAACAAGGAGCTCCAGGAAGAGGAAGAAAGCAGCAGTAGCAGCAGCAGCAGCAGCAGCAGCAGTGAGG
AGAGTGAGGCGGAGCCGCAGCAGGAGAACCGTGCTCACTGCAGACAGGAGGATGTGGGCTTCCGCGGAAACAGCCCGGAAATGAGGGTTGAGCCACAGCC
GAGGATGTGGGTGCCGGAGAGCCCTGTGTGTAGGTCGGGAAGAGGTGAGAGTAAGTCTGAGAGCTGGAGTGAGGAGCTGCAGCCTGGCCACCCACGTGCC
TGGCCTCCATCCCCGGGCCGCTTTCGCGTGGAAGAAGGTGGCGGTGCACCTTTCTGCTCAGCAGATGGAAGCACGAGTGCAGAGAAGAGACACCTGGAGG
TTAGCAACGGAATGGACGAGCTGGCAGGTAGCCCATTTCCTGTGACGAGAATGTCTTCAAGATCAAGTGACGCAAAACCACTGCCCGCGTCCTATCCAGC
TGAACCTAGGGAGCCCCAGGAAAGTCCGAAAATCACCAGTGCTTTCAGCTCTGTGAAACCAAGTGAAGCGGTCCCTCGGAAGTTTGACAGTGGTGGAGAG
AGGGGGGCAGGGCTCCCACTGTCCCTGTCTAACAAGAACCGAGGGCTCTCAGCTCCAGACTTACGGTCTGTGGGGCTCACCCCTGGGCAAGAACAGGGTG
CCAGTGAGCTAGAGGGGTCTTTGGGTGAAGCAAGCACAATAGAAATCCCCCCAGGTGAGTCCTTGCAAGCCAGGGCTGCAAGGATCCTGGGCATTGAGGT
GGCGGTGGAGTCCCTCCTGCCGGGCATCCGGAGAGCGGGACAGAACCAGCCTGCTGAGCCCGATGCAAGTGCCTGCACCCCAGAGTCCCCCCAGGAAGAG
TTGCTATCTCGCCCAGCACCGGCAGATGTCCCCAGGGTGTCCACTGATGCCTTTTATGGCAGGAGGAAGTGCGGCTGGACCAAGAGCCCTCTCTTTGTAG
GGGACAGGGACAGTGCCAGGCGGGCTCCTCAGGCTTTTGAGCACTCAGATGTGGACGGGGTTGTCACCAGCACAGACCCTGTCCCTGAGCCTGAGCCCAG
CCCCTTGGAGTCCAAGTTCTTCGAACAAAAGGATGTGGAAACAAAACCACCCTTCAGGTCCACTTTATTCCATTTTGTAGAAAGAACCCCAAGTGTGGCA
GGCTCTGAAAAGAGACTTAGAAGCCCTTCCAAAGTGATTGAAAGTTTACAAGAGAAACTGGCCTCCCCGCCTAGGAGAGCAGACCCTGACCGCCTGATGA
GAATGAAAGAGGTGAGCTCAGTGTCACGGATGAGAGTCCTGAGCTTCAGGAATGCCGACTCCCAGGAGGACGCCGAGGAATTGAAGGCCACCACAAGGGG
CCAGGCCGGGCTCCCGGGAGGCCTTGTGTCTCCTGGCAGTGGGGACCGTGCCCAGAGATTGGGCCACTCACTCTCTGTGTCCAAGGACAGCATCTCCAGG
GAAGAGAAGGAGCATCCGGCAGCACAAAAGGAGAAGAGCATGGATCAAGACTTCTGGTGCCCAGATTCCTATGACCCTAGCAGAGTGGAGAGGGTGTGAT
GAAATGCCGGTGGAGCTTGCATTCCGTTGCGAATTGAGTATTCTCAAGTAGCTGGTAGATTTAGTCTATCAGCCCCACTTCCCCATGTAGAAGCTGGAAG
CTGCTGAGTTTTTAGCATCCTGATAACATTCTTTACCACTGCCACTAGGAAACTTGCCATCCTCTCAGAATTGCTTTGTGGCGATAAAGCAATCGTCCGT
TGAAACCATCTGTTTTTATAGCATGAAGATTTAATGCCTATAATTAGGAAGGAGTTTTCACAGAAACCCTCCCTCATGACAGATTTGACTAAGCTGGTAA
ATAGTTTGGTGTTGCTCTCATTCTGGGTGAAGATTTCAATGTGGAAGATCTAGCAAATGCTTTGGAAAGGCCTGTGAATGGTGTGCTCCCCTCTGTGTCT
CCATGGCCTGCAGTCCATGCTCTTGTGAAGGAGTTTGGGACACTGGCTGTTGCCCGGTGTTTCAGCACTTTCAGTTTAGGGGAAATGTGAATCAATAGGT
ATGATCCATTTCTAATCAATTTGGCCTTCTGCTGCTGGAAGTAACTTTACTTATAAGTAACTTGCCATCAGAGAATAAAAGCAATATCTTTTAAGTTCCT
GAAAAATTAAAACTTGTACTGTAATATACTAAGAGTATTATTTATCTGGCAGTGAAATATTTTGATCATTTGCAAACACGCCATTGTCTGCTTTGCACTC
AGTATTATCTATTTTTATTTTCTGTATGGGTATTTAGAAATTCTTTATATGAAAAATAATTGCTGGTTTAAAATAGACCATTTTAACAAAGTGACTATAT
TTCTTTTTACGAAAATGCTATTTTTCTATGATGTAAACAATTGTTAGGCGGCAGATTTTTAAGGAAGTATTATTTTATTTAAGAGTCTGTATCCCTTTGT
GTGAGAGGAACCCAAAGAGGGTTCACTTTTGCTTTAAAGCTCTGTCCCTTACCCACTGACAACTCTGCTACTTTTATTTTATCTTAGAAAATGTCAATAT
AGACATATCACAGGGTTAATAAAAGAAACTTTTCACAAAGATTTTTGTACAAGTGTAGCTATCAGGTTATATTTGAAAATAACCCTCTGAAAACCAGCCA
ACATTGTCATGACAATTTTTGCTGCCGTATCAACTAGAATTACCAAAAAACATAGTTTTATCTTTGTATGTGTGTGGGGATCTACCCTGAGACCATGCTT
TTCTTCCCACCCTGCCACCCCACCCCTTTAAAGAAATACGTATTTTTATCTAGAATGATCTTGAATTAGTCTCTGCATATTTTTAGAAAGTGCTTGGGGA
CATTATATATATGCCATTACAAAAGCATTATGAGGCCTATGTATTCTACTGTGTTTAATACTGCATTAACCTGCACAAAGTTTATGCATTTTTTCATGCA
TTTTTTTCCTTCTTTCTAAGTAAGGTATTCCTGACAACTAACATTCCCTAAATCATTTCCCCTCCCTCCCTCCCTCCCTCCCTTCCTTTCTTCCTTCCTT
CTGTCCTCCCTCCCTTGCTACCTCTTGCCCTCCTTCCTTCACCCTGTCCTCCTTTTCCCTTTTATTTTTTCCCCTTCTCTTTCATTTTATTTTCTTTTAG
AGAAACCACCTTATCTATTTTTAGACATTTCGAATTCCTAAAATGTGAACCGTTGGGTGATCTGTCCTTTGGCCCTAAAACGGCTGGCCGGGCTGTCCCG
GCCTGTTCTCATCTGTACCGTATGATTTTATTTCATAATAACTTTATGTATTTGGACTGTAACAAACAAAACAGAACCTAAGTCGCCCCGAAAAATCTTT
CCAAGCCTTTTCAAAACACTTATCTGCAGTCCAGAATTCAGCTCTTATGAAAAGTGAGAGTGCACTCCAGTTTTCACAGCAGCAATAAGTGCGGGAAACA
AAAAGATCCTCTTCCCAGGAAAAGTTGAGTGGGGAAGAGTTCAGACACTGTTGTAGCTGGTGAATCATTGAAGTCACCTGGTAGTACCAAATAAGGGCTG
AGGCGCCTGGAGGTCTTTGTGGGGTCTTCCCTCTTTAAATGCAAACGTAAGAAGGTATATGTGTATATACATTTATATACGTGCACATGTATACTCGTAC
ATGTATGCACACATACCCATACATGTATATGAACTCCGTTCTGATTTCCTCTGAAATTTTGTTGATACCATCTAAATACCTCTTTGAATCAAAATAACTT
AATTTTAGCTCATTCCTCAAGAGAAAGAGAAGGATCCCCAAGGAAGAAAAACTGTTGTACCTTCTGTGATTCTCAAACCAAAATGTGATGCGCTTCTGTT
TTGTTATCTTAAATTGTTGTATCATATCTTTCTGAAACCATTCTGAATTAAGTTGAAATTTTCAACATTTATACTTTAACTGTTCTAAATTTAAGCCTAC
ATGTAAATCTTTTTTGGGGGGAAGGTAACTTGAAAAGTTTAACTTGAAAATTTGACCTTTAAACTTTCATATTCTAAGGTAAATAATAGCCTATAACCAA
CAACAGCTTTCCCAGAGGTCTTGAATTTAACACTAATTGTTTAGTTATTGTTTCTATTTCTCATACATACATAACTTCGTTTTTTGTGGCTGGAAGAAAA
AGTTTCTATATTTTGTATTTGTCTTTGTTCTTCTCATGCACACAATTTACTGTTGGTGTTTAATAATTTGGAGCTCATAAAATTAAAAGTTGTAATTTTG
ACCATTTGGGCTAAAAATTATATGAGGGATTACATATGCAATGGATTAGTATTTCTTGATTTGCAAAAGAAGGGAAAATGATGGTAATTTAGCTCAAATT
GCCTTTCTTTGAAGAAAATTTCTGAATGACTGAAAACCAAATATCTATATTATCACTTTCAACCTCATGTTTCTGCAAAGTACAGAAAAACTCCTCACTG
ACAGTGCACCCAGCCCCTGACTGGGTTTTCAGGATTATGTCCATGTGCATAACTGCTTGGATTTCTTCTTTTAAAGTCCCTAAAACATGAATCTGTTCTT
TGAGATCCTGGTTTCCTTAGCAGAGTTGTAGGTTGCGGGTTTCATTCACGTGGAAATTCTAAGTAGAACTTTTGCTGCCCCATTTTACTGTTGGTGAAGG
GCCGTTGTTAATGGAAGTTTACGTTTTAAAACTCAGATGACTCAGAAACCAGACTGTGATCATTTTTTGCAGCAGCAAAATGACTTATTCTGACAGCATC
TCGGTTTGGGGCTTCTGAAGAAAAAGGATGAAGCTGATCTGTTGAAACAACTACTTTCCCAACTCGGAGGCAAAAGGGGCTGATAGAAGATAACATTCAC
CTACCATTTCATCTTGTGACCCCCAGAGATCACGTTTGCGTGTTCTGGCTGAGTTTTTTATTATTGTTTGTTTTAAATGATTAAATAATACACAATTAAA
TGTCAGGATAGCATCTCTTGCAAAGTGACCAGTGCAGCAGAATTGTCTTTCTATCCATATTTGAGCTTAGAGAAACATTTCCCATGTCCTAAGTTCTTAG
AAGCAATTACTTTAGCGTTGGGGAGCATTGTTCTACCAGACCCATTTATGCAGGGGAGATGAAGCTTAAAAGACGGGATGTGGGGTGGGAGTGTGTTTCT
TAAGCCGAAGCTGTTGCAGGCTGGGGGATTTTTGCATTTTCTTTTTGTTTTGTTTTTGACTGCAGATTCTGTACATCTGTCTGTGGGAGGAGAGTTGCTA
CTCAGGACAGGATTTAAGAGACACATTCCAGTGACCTTTAAGAATCTGCATGGCGGGAGGTCCTTCTCCAGGAGTGTGGGTTGGTCCACTCTGGGACCCA
CCACACTAAGAAGGGGGAGATGATAAAATAACATTAAAGGAAGAATGGCCTCCAGCCTGCAGGTTTTGTTGGAAAGAAATAAAAAGGGAGTCATTAAGAC
CATAAATTCAGATTGAGGCCTCTTGAAAAGGTTGATGTGGGCTAGCAACCTGCCTGTCGAAACAGTCCTTGGTTCATCAGCAGTGTGGGAAGGCAGCCAA
GGCTCCTGCAGATTCCTGGCATCGACCTTGGAAAGCCTCTGCGATACTTGTGTGTACGAATACAGCAGAGGACAGGGAGGTCCTTGTTCTGTGGTCTCTG
TTTAGTGACTGAAACTTAAACCCAAAGGCAAGCCCAGATTGTCTGGCCGTTCATCCCCATGCTTTGATAGGGGTTAGGAGGAACCCTTTCCGTATGAAAG
ACAGGCCCTACTAGGGCTTACAACCAAGCCAAAGGACCATCTCTTCTTTCTTCCACCTCCCTTCACCCCTGCCCCGCAGCAGAGCCGAGATGTGAGACAT
TCATTGTCACGGAGCAAGGAGACAAAGGCAAGTTCAAGTTGAGAAGCATATGGCAGCAAACAGAAATGAAAACCATATGTCCCAGCAAGGGGAAAAGCAG
TCATTTCCAGATTATAAAAATCAATGAAGTACTCTCCACCTAGGTCAGCTGAAATTCGAGCCCTCACAGTCAGGCCTGTCAGAGAAGTTAAGCAGAAACA
TCTCGGGGGGACTTCTAAAATTTAGTGAAGACAAGGCCTTGCAACTCCAAAGAAACTTTTTTTCCCCCCCTTGAAACAGGGTCTTGCTCTGTTGCCCAGC
CTGGAGTGCAGTGGTGCAGTCACGGCTCACTGCAGCCTCAAGCTCCTGGGCTCAAGCACTATCCCCACCTCAACCTCCTTAGTAGCTGGGACTACAGGTG
CACACCACCATGCCCAGCTAACCACAGAAACTTTCATCTCTTCATTTTTTCTTTGGGCACCATTAATACCTAAGACAGGTAGAAAGGGTCCCAGAAAGAC
ACCATTGGTAATGGCCGATTGCCGGCTGCAGTCATCGCCCCCAGATCAGGCTGGTACAGGATGCCTTAAGGTGATGAGAGGTGAGGGTGCATGAAGAATA
ATGAGCACAGGGAAGAGAGAAGCAGGACAAAGTAGCAGATAAAATGCCGGCAAAGCACAGATGAATGTCTTCAAGAAGCTCTTGTATTTCTCTGCACAGT
GTAAATATCCTTGCTATTTCAGGATGGCGGCTGGCCTGCTCAGTAACATACATGTTCCAAATAAAGATTTTGCATGAAAGTA
  • refseq_KIAA1462.F2 (forward primer)
  • refseq_KIAA1462.R2 (reverse primer)
  • Single exon skipping

Frame 0

VPGRPERRRWRREAA*GSRSCWVLPPPWFQWLS
FAEAQASCTV*KTS*SLMDTSCQETPQHHARITP
RGARQRGLGHEQARACRTGMRMALRPSHIVRRP
RGKDM*VTPKAAAAHREATGSPRALLLPEPRRR
GFVINPPQHGPLIPRLVTTKPTGEEDGKKPGARS
RGSTKTWRPEEWPKPTACLST*GRVHGKLEEGQ
SM**RSQFGKKNCECQVLPSGRTSAWKAGTSQG
N*GGRCLMEMGRDCFKTCTHSFKENMC*ILKTKG
SLAHCLEFFPPRA*VARKFPFH*MKDIHLKCHR
ILPLAHQIWTPRGILRRVAAQPHFPGLSLGGPS
SPHLTARTSSLGEERTAVTLRTASRWTPMSPGMS
SACQTLDWNLQCTCLRPHTDRPRRTSQTPTWKT
RCP*MCVAVTVNSSLRPRRLGPAVSLLQAPLEL
GMSMV*APACLRGSPHIPDLSLPMTASFSTFPLM
IHGYDILN*LSPRVSVKT*SLTINHITPVLSLL
KSRLMEECSLMVPFGIHRA*YPRRGMREAWSWP
IPAPGGCGASPPGMGKTVASPTRETAVWQGDSGL
M*EAASTGTLEDKFPPLTHRARAPAKLKPSSKS
SKLGLGPRKVQRKK*TRLYFAWFLSQ*NQNHIC
QIEIWTTMT*SPVLIKRMGLIRARLCKNRVC*AC
LPPTWSCRPSQEAWVGERSSKNKI*GNQKKTDK
QMTSVSSTLQSTENSSILALGQGTGTEISKHKP
VSPRSPKVRSCSLVQSWEGRVVQH*VQNVQTLLP
PKLRRTQHSLPVITNRGQVPVT*KVTGPSAHPA
TVRSQGLPCPWTRHRRQKQAEVSPAWMSTGLEP
TLGLSGRW*RGSPRALATVNNSLGSFS*NRSAVV
PGI*SVS*KVLTRSSRKRKKAAVAAAAAAAAVR
RVRRSRSRRTVLTADRRMWASAETARK*GLSHS
RGCGCRRALCVGREEVRVSLRAGVRSCSLATHVP
GLHPRAAFAWKKVAVHLSAQQMEARVQRRDTWR
LATEWTSWQVAHFL*RECLQDQVTQNHCPRPIQ
LNLGSPRKVRKSPVLSAL*NQVKRSLGSLTVVER
GGQGSHCPCLTRTEGSQLQTYGLWGSPLGKNRV
PVS*RGLWVKQAQ*KSPQVSPCKPGLQGSWALR
WRWSPSCRASGERDRTSLLSPMQVPAPQSPPRKS
CYLAQHRQMSPGCPLMPFMAGGSAAGPRALSL*
GTGTVPGGLLRLLSTQMWTGLSPAQTLSLSLSP
APWSPSSSNKRMWKQNHPSGPLYSIL*KEPQVWQ
ALKRDLEALPK*LKVYKRNWPPRLGEQTLTA**
E*KR*AQCHG*ES*ASGMPTPRRTPRN*RPPQG
ARPGSREALCLLAVGTVPRDWATHSLCPRTASPG
KRRSIRQHKRRRAWIKTSGAQIPMTLAEWRGCD
EMPVELAFRCELSILK*LVDLVYQPHFPM*KLE
AAEFLAS**HSLPLPLGNLPSSQNCFVAIKQSSV
ETICFYSMKI*CL*LGRSFHRNPPS*QI*LSW*
IVWCCSHSG*RFQCGRSSKCFGKACEWCAPLCV
SMACSPCSCEGVWDTGCCPVFQHFQFRGNVNQ*V
*SISNQFGLLLLEVTLLISNLPSENKSNIF*VP
EKLKLVL*YTKSIIYLAVKYFDHLQTRHCLLCT
QYYLFLFSVWVFRNSLYEK*LLV*NRPF*QSDYI
SFYENAIFL*CKQLLGGRFLRKYYFI*ESVSLC
VRGTQRGFTFALKLCPLPTDNSATFILS*KMSI
*TYHRVNKRNFSQRFLYKCSYQVIFENNPLKTSQ
HCHDNFCCRIN*NYQKT*FYLCMCVGIYPETML
FFPPCHPTPLKKYVFLSRMILN*SLHIFRKCLG
TLYICHYKSIMRPMYSTVFNTALTCTKFMHFFMH
FFPSF*VRYS*QLTFPKSFPLPPSLPPFLSSFL
LSSLPCYLLPSFLHPVLLFPFIFSPSLSFYFLL
EKPPYLFLDISNS*NVNRWVICPLALKRLAGLSR
PVLICTV*FYFIITLCIWTVTNKTEPKSPRKIF
PSLFKTLICSPEFSSYEK*ECTPVFTAAISAGN
KKILFPGKVEWGRVQTLL*LVNH*SHLVVPNKG*
GAWRSLWGLPSLNANVRRYMCIYIYIRAHVYSY
MYAHIPIHVYELRSDFL*NFVDTI*IPL*IKIT
*F*LIPQEKEKDPQGRKTVVPSVILKPKCDALLF
CYLKLLYHIFLKPF*IKLKFSTFIL*LF*I*AY
M*IFFGGKVT*KV*LENLTFKLSYSKVNNSL*P
TTAFPEVLNLTLIV*LLFLFLIHT*LRFLWLEEK
VSIFCICLCSSHAHNLLLVFNNLELIKLKVVIL
TIWAKNYMRDYICNGLVFLDLQKKGK*W*FSSN
CLSLKKISE*LKTKYLYYHFQPHVSAKYRKTPH*
QCTQPLTGFSGLCPCA*LLGFLLLKSLKHESVL
*DPGFLSRVVGCGFHSRGNSK*NFCCPILLLVK
GRC*WKFTF*NSDDSETRL*SFFAAAK*LILTAS
RFGASEEKG*S*SVETTTFPTRRQKGLIEDNIH
LPFHLVTPRDHVCVFWLSFLLLFVLND*IIHN*
MSG*HLLQSDQCSRIVFLSIFELRETFPMS*VLR
SNYFSVGEHCSTRPIYAGEMKLKRRDVGWECVS
*AEAVAGWGIFAFSFCFVFDCRFCTSVCGRRVA
TQDRI*ETHSSDL*ESAWREVLLQECGLVHSGTH
HTKKGEMIK*H*RKNGLQPAGFVGKK*KGSH*D
HKFRLRPLEKVDVG*QPACRNSPWFISSVGRQP
RLLQIPGIDLGKPLRYLCVRIQQRTGRSLFCGLC
LVTET*TQRQAQIVWPFIPML**GLGGTLSV*K
TGPTRAYNQAKGPSLLSSTSLHPCPAAEPRCET
FIVTEQGDKGKFKLRSIWQQTEMKTICPSKGKSS
HFQIIKINEVLST*VS*NSSPHSQACQRS*AET
SRGDF*NLVKTRPCNSKETFFPPLETGSCSVAQ
PGVQWCSHGSLQPQAPGLKHYPHLNLLSSWDYRC
TPPCPANHRNFHLFIFSLGTINT*DR*KGSQKD
TIGNGRLPAAVIAPRSGWYRMP*GDER*GCMKN
NEHREERSRTK*QIKCRQSTDECLQEALVFLCTV
*ISLLFQDGGWPAQ*HTCSK*RFCMKV

Frame 1

SPAGRSGGGGGARRHEGAARAGSCHHHGSSG*A
LLKPRHHVQCRRPPDLSWIQAVKRPPSITRG*P
QGAPGSEDWDTSRPGPAERA*GWPCGPRTS*DVR
GERTCE*LRKPPQHTERPRGAPEHFCFQNLGGG
VL*STPLSMVLSSPDW*RPSLPEKRTARSQEPE
AEGARKPGGQRNGPSPQPACPREGGSMGSWRKVR
ACDEEASLGRRIANVRSCQVAERQPGKLEPAKE
IREADV*WRWGETVSRPVPIHSRRTCVEFSKQR
EVSLTA*SSFPREPELHGNSHSIK*KTFT*NATV
SSHLRTKFGLHEEF*EEWLLSPISPA*VWEAPQ
APILQLAPAV*GRSGQQ*LSGQPADGRLCPQA*
ALPVRPWIGTSSVRASALIQIAPAEHPKPLLGRH
GAHKCVWRSQSTAVSDREGWGQRSASFRPPWNW
E*VWCEPPLASGAPRTSPTCHCL*RLRSVHSL*
*STVTTF*TSSAPGFL*RHKA*R*II*LQSCHCS
RAGSWRNAA*WCHLESTELNTPVGG*ERPGLGR
FQPPVAVGPAPRGWGKQWPPQPERPLCGKGTVA
*CERQPARAHWKTSFLPLLTGREHLRNSNQAQKV
PNWDSDQEKFKEKNERDYILLGFYPSEIRITSA
R*RYGQQ*LKAQC*SKEWV**EPGSARTESAEH
VFHRPGAAGPHRKHGWENGVPKTRSRGTRRRQTN
K*PQFHPPYKAQRTQAFWLLARAPVQRSANTNQ
FLRGAPKFAAAPWCKAGRAESCSIESKMFRPCC
LRSSDAHSIPYR*SQTEAKCP*PERSQVPQPIQQ
QCVLKDFLVRGPGTDAKSRPKSALRGCPRAWSP
PWA*AGGGEGGAHGPLQQ*TTLWAVSPETGQPS
SLGFDQSVRKF*QGAPGRGRKQQ*QQQQQQQQ*G
E*GGAAAGEPCSLQTGGCGLPRKQPGNEG*ATA
EDVGAGEPCV*VGKR*E*V*ELE*GAAAWPPTC
LASIPGPLSRGRRWRCTFLLSRWKHECREETPGG
*QRNGRAGR*PISCDENVFKIK*RKTTARVLSS
*T*GAPGKSENHQCFQLCETK*SGPSEV*QWWR
EGGRAPTVPV*QEPRALSSRLTVCGAHPWARTGC
Q*ARGVFG*SKHNRNPPR*VLASQGCKDPGH*G
GGGVPPAGHPESGTEPAC*ARCKCLHPRVPPGR
VAISPSTGRCPQGVH*CLLWQEEVRLDQEPSLCR
GQGQCQAGSSGF*ALRCGRGCHQHRPCP*A*AQ
PLGVQVLRTKGCGNKTTLQVHFIPFCRKNPKCG
RL*KET*KPFQSD*KFTRETGLPA*ESRP*PPDE
NERGELSVTDESPELQECRLPGGRRGIEGHHKG
PGRAPGRPCVSWQWGPCPEIGPLTLCVQGQHLQ
GREGASGSTKGEEHGSRLLVPRFL*P*QSGEGVM
KCRWSLHSVAN*VFSSSW*I*SISPTSPCRSWK
LLSF*HPDNILYHCH*ETCHPLRIALWR*SNRP
LKPSVFIA*RFNAYN*EGVFTETLPHDRFD*AGK
*FGVALILGEDFNVEDLANALERPVNGVLPSVS
PWPAVHALVKEFGTLAVARCFSTFSLGEM*INR
YDPFLINLAFCCWK*LYL*VTCHQRIKAISFKFL
KN*NLYCNILRVLFIWQ*NILIICKHAIVCFAL
SIIYFYFLYGYLEILYMKNNCWFKIDHFNKVTI
FLFTKMLFFYDVNNC*AADF*GSIILFKSLYPFV
*EEPKEGSLLL*SSVPYPLTTLLLLFYLRKCQY
RHITGLIKETFHKDFCTSVAIRLYLKITL*KPA
NIVMTIFAAVSTRITKKHSFIFVCVWGSTLRPCF
SSHPATPPL*RNTYFYLE*S*ISLCIFLESAWG
HYIYAITKAL*GLCILLCLILH*PAQSLCIFSC
IFFLLSK*GIPDN*HSLNHFPSLPPSLPSFLPSF
CPPSLATSCPPSFTLSSFSLLFFPLLFHFIFF*
RNHLIYF*TFRIPKM*TVG*SVLWP*NGWPGCP
GLFSSVPYDFIS**LYVFGL*QTKQNLSRPEKSF
QAFSKHLSAVQNSALMKSESALQFSQQQ*VRET
KRSSSQEKLSGEEFRHCCSW*IIEVTW*YQIRA
EAPGGLCGVFPL*MQT*EGICVYTFIYVHMYTRT
CMHTYPYMYMNSVLISSEILLIPSKYLFESK*L
NFSSFLKRKRRIPKEEKLLYLL*FSNQNVMRFC
FVILNCCIISF*NHSELS*NFQHLYFNCSKFKPT
CKSFLGGR*LEKFNLKI*PLNFHILR*IIAYNQ
QQLSQRS*I*H*LFSYCFYFSYIHNFVFCGWKK
KFLYFVFVFVLLMHTIYCWCLIIWSS*N*KL*F*
PFGLKII*GITYAMD*YFLICKRRENDGNLAQI
AFL*RKFLND*KPNIYIITFNLMFLQSTEKLLT
DSAPSP*LGFQDYVHVHNCLDFFF*SP*NMNLFF
EILVSLAEL*VAGFIHVEILSRTFAAPFYCW*R
AVVNGSLRFKTQMTQKPDCDHFLQQQNDLF*QH
LGLGLLKKKDEADLLKQLLSQLGGKRG**KITFT
YHFIL*PPEITFACSG*VFYYCLF*MIK*YTIK
CQDSISCKVTSAAELSFYPYLSLEKHFPCPKFL
EAITLALGSIVLPDPFMQGR*SLKDGMWGGSVFL
KPKLLQAGGFLHFLFVLFLTADSVHLSVGGELL
LRTGFKRHIPVTFKNLHGGRSFSRSVGWSTLGP
TTLRRGR**NNIKGRMASSLQVLLERNKKGVIKT
INSD*GLLKRLMWASNLPVETVLGSSAVWEGSQ
GSCRFLASTLESLCDTCVYEYSRGQGGPCSVVS
V**LKLKPKGKPRLSGRSSPCFDRG*EEPFPYER
QALLGLTTKPKDHLFFLPPPFTPAPQQSRDVRH
SLSRSKETKASSS*EAYGSKQK*KPYVPARGKA
VISRL*KSMKYSPPRSAEIRALTVRPVREVKQKH
LGGTSKI**RQGLATPKKLFFPPLKQGLALLPS
LECSGAVTAHCSLKLLGSSTIPTSTSLVAGTTG
AHHHAQLTTETFISSFFLWAPLIPKTGRKGPRKT
PLVMADCRLQSSPPDQAGTGCLKVMRGEGA*RI
MSTGKREAGQSSR*NAGKAQMNVFKKLLYFSAQ
CKYPCYFRMAAGLLSNIHVPNKDFA*K

Frame 2

PRPAGAAAVAARGGMREPLVLGPATTMVPVVEL
C*SPGIMYSVEDLLISHGYKLSRDPPASREDNP
KGRQAARTGTRAGQGLQNGHEDGPAALAHRKTS
AGKGHVSDSESRRSTPRGHGEPQSTSASRTSEAG
FCNQPPSAWSSHPPTGNDQAYRRRGRQEARSQK
PREHENLEARGMAQAHSLPVHVREGPWEVGGRS
EHVMKKPVWEEELRMSGPAKWQNVSLESWNQPRK
LGRQMSDGDGERLFQDLYPFIQGEHVLNSQNKG
KSRSLPRVLSPESLSCTEIPIPLNERHSPKMPP
YPPTCAPNLDSTRNSEKSGCSAPFPRPKFGRPLK
PPSYSSHQQSRGGADSSDSQDSQQMDAYVPRHE
LCLSDPGLEPPVYVPPPSYRSPPQNIPNPYLED
TVPINVCGGHSQQQSPTEKAGASGQPPSGPPGTG
NEYGVSPRLPQGLPAHPRPVTAYDGFVQYIPFD
DPRLRHFKLAQPQGFCEDIKLDDKSYNSSPVTA
QEPAHGGMQPDGAIWNPQSLIPPSGDERGLVLAD
SSPRWLWGQPPGDGENSGLPNQRDRCVARGQWP
DVRGSQHGHTGRQVSSPYSQGESTCETQTKLKK
FQTGTRTKKSSKKKMNETIFCLVSIPVKSESHLP
DRDMDNNDLKPSADQKNGSDKSPALQEQSLLSM
SSTDLELQALTGSMGGRTEFQKQDLGEPEEDRQ
TNDLSFIHLTKHRELKHSGSWPGHRYRDQQTQTS
FSEEPQSSQLLPGAKLGGPSRAALSPKCSDPAA
SEAQTHTAFPTGDHKQRPSARNLKGHRSLSPSS
NSAFSRTSLSVDQAPTPKAGRSQPCVDVHGLGAH
PGPKREVVKGEPTGPCNSKQLFGQFLLKPVSRR
PWDLISQLESFNKELQEEEESSSSSSSSSSSSE
ESEAEPQQENRAHCRQEDVGFRGNSPEMRVEPQP
RMWVPESPVCRSGRGESKSESWSEELQPGHPRA
WPPSPGRFRVEEGGGAPFCSADGSTSAEKRHLE
VSNGMDELAGSPFPVTRMSSRSSDAKPLPASYPA
EPREPQESPKITSAFSSVKPSEAVPRKFDSGGE
RGAGLPLSLSNKNRGLSAPDLRSVGLTPGQEQG
ASELEGSLGEASTIEIPPGESLQARAARILGIEV
AVESLLPGIRRAGQNQPAEPDASACTPESPQEE
LLSRPAPADVPRVSTDAFYGRRKCGWTKSPLFV
GDRDSARRAPQAFEHSDVDGVVTSTDPVPEPEPS
PLESKFFEQKDVETKPPFRSTLFHFVERTPSVA
GSEKRLRSPSKVIESLQEKLASPPRRADPDRLM
RMKEVSSVSRMRVLSFRNADSQEDAEELKATTRG
QAGLPGGLVSPGSGDRAQRLGHSLSVSKDSISR
EEKEHPAAQKEKSMDQDFWCPDSYDPSRVERV*
*NAGGACIPLRIEYSQVAGRFSLSAPLPHVEAGS
C*VFSILITFFTTATRKLAILSELLCGDKAIVR
*NHLFL*HEDLMPIIRKEFSQKPSLMTDLTKLV
NSLVLLSFWVKISMWKI*QMLWKGL*MVCSPLCL
HGLQSMLL*RSLGHWLLPGVSALSV*GKCESIG
MIHF*SIWPSAAGSNFTYK*LAIRE*KQYLLSS
*KIKTCTVIY*EYYLSGSEIF*SFANTPLSALHS
VLSIFIFCMGI*KFFI*KIIAGLK*TILTK*LY
FFLRKCYFSMM*TIVRRQIFKEVLFYLRVCIPL
CERNPKRVHFCFKALSLTH*QLCYFYFILENVNI
DISQG**KKLFTKIFVQV*LSGYI*K*PSENQP
TLS*QFLLPYQLELPKNIVLSLYVCGDLP*DHA
FLPTLPPHPFKEIRIFI*NDLELVSAYF*KVLGD
IIYMPLQKHYEAYVFYCV*YCINLHKVYAFFHA
FFSFFLSKVFLTTNIP*IISPPSLPPSLPFFLP
SVLPPLLPLALLPSPCPPFPFYFFPFSFILFSFR
ETTLSIFRHFEFLKCEPLGDLSFGPKTAGRAVP
ACSHLYRMILFHNNFMYLDCNKQNRT*VAPKNL
SKPFQNTYLQSRIQLL*KVRVHSSFHSSNKCGKQ
KDPLPRKS*VGKSSDTVVAGESLKSPGSTK*GL
RRLEVFVGSSLFKCKRKKVYVYIHLYTCTCILV
HVCTHTHTCI*TPF*FPLKFC*YHLNTSLNQNNL
ILAHSSREREGSPRKKNCCTFCDSQTKM*CASV
LLS*IVVSYLSETILN*VEIFNIYTLTVLNLSL
HVNLFWGEGNLKSLT*KFDL*TFIF*GK**PITN
NSFPRGLEFNTNCLVIVSISHTYITSFFVAGRK
SFYILYLSLFFSCTQFTVGV**FGAHKIKSCNF
DHLG*KLYEGLHMQWISIS*FAKEGKMMVI*LKL
PFFEENF*MTENQISILSLSTSCFCKVQKNSSL
TVHPAPDWVFRIMSMCITAWISSFKVPKT*ICS
LRSWFP*QSCRLRVSFTWKF*VELLLPHFTVGEG
PLLMEVYVLKLR*LRNQTVIIFCSSKMTYSDSI
SVWGF*RKRMKLIC*NNYFPNSEAKGADRR*HS
PTISSCDPQRSRLRVLAEFFIIVCFK*LNNTQLN
VRIASLAK*PVQQNCLSIHI*A*RNISHVLSS*
KQLL*RWGALFYQTHLCRGDEA*KTGCGVGVCF
LSRSCCRLGDFCIFFLFCF*LQILYICLWEESCY
SGQDLRDTFQ*PLRICMAGGPSPGVWVGPLWDP
PH*EGGDDKITLKEEWPPACRFCWKEIKRESLR
P*IQIEAS*KG*CGLATCLSKQSLVHQQCGKAAK
APADSWHRPWKASAILVCTNTAEDREVLVLWSL
FSD*NLNPKASPDCLAVHPHALIGVRRNPFRMK
DRPY*GLQPSQRTISSFFHLPSPLPRSRAEM*DI
HCHGARRQRQVQVEKHMAANRNENHMSQQGEKQ
SFPDYKNQ*STLHLGQLKFEPSQSGLSEKLSRN
ISGGLLKFSEDKALQLQRNFFSPP*NRVLLCCPA
WSAVVQSRLTAASSSWAQALSPPQPP**LGLQV
HTTMPS*PQKLSSLHFFFGHH*YLRQVERVPER
HHW*WPIAGCSHRPQIRLVQDALR**EVRVHEE*
*AQGREKQDKVADKMPAKHR*MSSRSSCISLHS
VNILAISGWRLACSVTYMFQIKILHES

Sequence XM_166132

GAGCTCAAACTTAGAGCTGCTATCGGAGGAGGATTTTAGATTTAGGAAATTCTCAGCAGAGCATCCGAGGGGCTTTTGAAAAATTCAATTCTTTAGACGC
TCATGAAGAAATCAGGGATTTCCTCAGTGCTGGGTCCTGCCACCACCATGGTTCCAGTGGTTGAGCTTTGCTGAAGCCCAGGCATCATGTACAGTGTAGA
AGACCTCCTGATCTCTCATGGATACAAGCTGTCAAGAGACCCCCCAGCATCACGCGAGGATAACCCCAAGGGGCGCCAGGCAGCGAGGACTGGGACACGA
GCAGGCCAGGGCCTGCAGAACGGGCATGAGGATGGCCCTGCGGCCCTCGCACATCGTAAGACGTCCGCGGGGAAAGGACATGTGAGTGACTCCGAAAGCC
GC
CGCAGCACACCGAGAGGCCACGGGGAGCCCCAGAGCACTTCTGCTTCCAGAACCTCGGAGGCGGGGTGCCCAATAGAGAACTGAAAATTGGAGGGAAA
CAGAAAG
GTTTTGTAATCAACCCCCCTCAGCATGGTCCTCTCATCCCCCGACTGGTAACGACCAAGCCTACCGGAGAAGAGGACGGCAAGAAGCCAGGAG
CCAGAAGCCGAGGGAGCACGAAAACCTGGAGGCCAGAGGAATGGCCCAAGCCCACAGCCTGCCTGTCCACGTGAGGGAGGGTCCATGGGAAGTTGGAGGA
AGGTCAGAGCATGTGATGAAGAAGCCAGTTTGGGAAGAAGAATTGCGAATGTCAGGTCCTGCCAAGTGGCAGAACGTCAGCCTGGAAAGCTGGAACCAGC
CAAGGAAATTAGGGAGGCAGATGTCTGATGGAGATGGGGAGAGACTGTTTCAAGACCTGTACCCATTCATTCAAGGAGAACATGTGTTGAATTCTCAAAA
CAAAGGGAAGTCTCGCTCACTGCCTAGAGTTCTTTCCCCCGAGAGCCTGAGTTGCACGGAAATTCCCATTCCATTAAATGAAAGACATTCACCTAAAATG
CCACCGTATCCTCCCACTTGCGCACCAAATTTGGACTCCACGAGGAATTCTGAGAAGAGTGGCTGCTCAGCCCCATTTCCCCGGCCTAAGTTTGGGAGGC
CCCTCAAGCCCCCATCTTACAGCTCGCACCAGCAGTCTAGGGGAGGAGCGGACAGCAGTGACTCTCAGGACAGCCAGCAGATGGACGCCTATGTCCCCAG
GCATGAGCTCTGCCTGTCAGACCCTGGATTGGAACCTCCAGTGTACGTGCCTCCGCCCTCATACAGATCGCCCCCGCAGAACATCCCAAACCCCTACTTG
GAAGACACGGTGCCCATAAATGTGTGTGGCGGTCACAGTCAACAGCAGTCTCCGACCGAGAAGGCTGGGGCCAGCGGTCAGCCTCCTTCAGGCCCCCCTG
GAACTGGGAATGAGTATGGTGTGAGCCCCCGCTTGCCTCAGGGGCTCCCCGCACATCCCCGACCTGTCACTGCCTATGACGGCTTCGTTCAGTACATTCC
CTTTGATGATCCACGGTTACGACATTTTAAACTAGCTCAGCCCCAGGGTTTCTGTGAAGACATAAAGCTTGACGATAAATCATATAACTCCAGTCCTGTC
ACTGCTCAAGAGCCGGCTCATGGAGGAATGCAGCCTGATGGTGCCATTTGGAATCCACAGAGCTTAATACCCCCGTCGGGGGATGAGAGAGGCCTGGTCT
TGGCCGATTCCAGCCCCCGGTGGCTGTGGGGCCAGCCCCCCGGGGATGGGGAAAACAGTGGCCTCCCCAACCAGAGAGACCGCTGTGTGGCAAGGGGACA
GTGGCCTGATGTGAGAGGCAGCCAGCACGGGCACACTGGAAGACAAGTTTCCTCCCCTTACTCACAGGGCGAGAGCACCTGCGAAACTCAAACCAAGCTC
AAAAAGTTCCAAACTGGGACTCGGACCAAGAAAAGTTCAAAGAAAAAAATGAACGAGACTATATTTTGCTTGGTTTCTATCCCAGTGAAATCAGAATCAC
ATCTGCCAGATAGAGATATGGACAACAATGACTTAAAGCCCAGTGCTGATCAAAAGAATGGGTCTGATAAGAGCCCGGCTCTGCAAGAACAGAGTCTGCT
GAGCATGTCTTCCACCGACCTGGAGCTGCAGGCCCTCACAGGAAGCATGGGTGGGAGAACGGAGTTCCAAAAACAAGATCTAGGGGAACCAGAAGAAGAC
AGACAAACAAATGACCTCAGTTTCATCCACCTTACAAAGCACAGAGAACTCAAGCATTCTGGCTCTTGGCCAGGGCACCGGTACAGAGATCAGCAAACAC
AAACCAGTTTCTCCGAGGAGCCCCAAAGTTCGCAGCTGCTCCCTGGTGCAAAGCTGGGAGGGCCGAGTCGTGCAGCATTGAGTCCAAAATGTTCAGACCC
TGCTGCCTCCGAAGCTCAGACGCACACAGCATTCCCTACCGGTGATCACAAACAGAGGCCAAGTGCCCGTAACCTGAAAGGTCACAGGTCCCTCAGCCCA
TCCAGCAACAGTGCGTTCTCAAGGACTTCCTTGTCCGTGGACCAGGCACCGACGCCAAAAGCAGGCCGAAGTCAGCCCTGCGTGGATGTCCACGGGCTTG
GAGCCCACCCTGGGCCTAAGCGGGAGGTGGTGAAGGGGGAGCCCACGGGCCCTTGCAACAGTAAACAACTCTTTGGGCAGTTTCTCCTGAAACCGGTCAG
CCGTCGTCCCTGGGATTTGATCAGTCAGTTAGAAAGTTTTAACAAGGAGCTCCAGGAAGAGGAAGAAAGCAGCAGTAGCAGCAGCAGCAGCAGCAGCAGC
AGTGAGGAGAGTGAGGCGGAGCCGCAGCAGGAGAACCGTGCTCACTGCAGACAGGAGGATGTGGGCTTCCGCGGAAACAGCCCGGAAATGAGGGTTGAGC
CACAGCCGAGGATGTGGGTGCCGGAGAGCCCTGTGTGTAGGTCGGGAAGAGGTGAGAGTAAGTCTGAGAGCTGGAGTGAGGAGCTGCAGCCTGGCCACCC
ACGTGCCTGGCCTCCATCCCCGGGCCGCTTTCGCGTGGAAGAAGGTGGCGGTGCACCTTTCTGCTCAGCAGATGGAAGCACGAGTGCAGAGAAGAGACAC
CTGGAGGTTAGCAACGGAATGGACGAGCTGGCAGGTAGCCCATTTCCTGTGACGAGAATGTCTTCAAGATCAAGTGACGCAAAACCACTGCCCGCGTCCT
ATCCAGCTGAACCTAGGGAGCCCCAGGAAAGTCCGAAAATCACCAGTGCTTTCAGCTCTGTGAAACCAAGTGAAGCGGTCCCTCGGAAGTTTGACAGTGG
TGGAGAGAGGGGGGCAGGGCTCCCACTGTCCCTGTCTAACAAGAACCGAGGGCTCTCAGCTCCAGACTTACGGTCTGTGGGGCTCACCCCTGGGCAAGAA
CAGGGTGCCAGTGAGCTAGAGGGGTCTTTGGGTGAAGCAAGCACAATAGAAATCCCCCCAGGTGAGTCCTTGCAAGCCAGGGCTGCAAGGATCCTGGGCA
TTGAGGTGGCGGTGGAGTCCCTCCTGCCGGGCATCCGGAGAGCGGGACAGAACCAGCCTGCTGAGCCCGATGCAAGTGCCTGCACCCCAGAGTCCCCCCA
GGAAGAGTTGCTATCTCGCCCAGCACCGGCAGATGTCCCCAGGGTGTCCACTGATGCCTTTTATGGCAGGAGGAAGTGCGGCTGGACCAAGAGCCCTCTC
TTTGTAGGGGACAGGGACAGTGCCAGGCGGGCTCCTCAGGCTTTTGAGCACTCAGATGTGGACGGGGTTGTCACCAGCACAGACCCTGTCCCTGAGCCTG
AGCCCAGCCCCTTGGAGTCCAAGTTCTTCGAACAAAAGGATGTGGAAACAAAACCACCCTTCAGGTCCACTTTATTCCATTTTGTAGAAAGAACCCCAAG
TGTGGCAGGCTCTGAAAAGAGACTTAGAAGCCCTTCCAAAGTGATTGAAAGTTTACAAGAGAAACTGGCCTCCCCGCCTAGGAGAGCAGACCCTGACCGC
CTGATGAGAATGAAAGAGGTGAGCTCAGTGTCACGGATGAGAGTCCTGAGCTTCAGGAATGCCGACTCCCAGGAGGACGCCGAGGAATTGAAGGCCACCA
CAAGGGGCCAGGCCGGGCTCCCGGGAGGCCTTGTGTCTCCTGGCAGTGGGGACCGTGCCCAGAGATTGGGCCACTCACTCTCTGTGTCCAAGGACAGCAT
CTCCAGGGAAGAGAAGGAGCATCCGGCAGCACAAAAGGAGAAGAGCATGGATCAAGACTTCTGGTGCCCAGATTCCTATGACCCTAGCAGAGTGGAGAGG
GTGTGATGAAATGCCGGTGGAGCTTGCATTCCGTTGCGAATTGAGTATTCTCAAGTAGCTGGTAGATTTAGTCTATCAGCCCCACTTCCCCATGTAGAAG
CTGGAAGCTGCTGAGTTTTTAGCATCCTGATAACATTCTTTACCACTGCCACTAGGAAACTTGCCATCCTCTCAGAATTGCTTTGTGGCGATAAAGCAAT
CGTCCGTTGAAACCATCTGTTTTTATAGCATGAAGATTTAATGCCTATAATTAGGAAGGAGTTTTCACAGAAACCCTCCCTCATGACAGATTTGACTAAG
CTGGTAAATAGTTTGGTGTTGCTCTCATTCTGGGTGAAGATTTCAATGTGGAAGATCTAGCAAATGCTTTGGAAAGGCCTGTGAATGGTGTGCTCCCCTC
TGTGTCTCCATGGCCTGCAGTCCATGCTCTTGTGAAGGAGTTTGGGACACTGGCTGTTGCCCGGTGTTTCAGCACTTTCAGTTTAGGGGAAATGTGAATC
AATAGGTATGATCCATTTCTAATCAATTTGGCCTTCTGCTGCTGGAAGTAACTTTACTTATAAGTAACTTGCCATCAGAGAATAAAAGCAATATCTTTTA
AGTTCCTGAAAAATTAAAACTTGTACTGTAATATACTAAGAGTATTATTTATCTGGCAGTGAAATATTTTGATCATTTGCAAACACGCCATTGTCTGCTT
TGCACTCAGTATTATCTATTTTTATTTTCTGTATGGGTATTTAGAAATTCTTTATATGAAAAATAATTGCTGGTTTAAAATAGACCATTTTAACAAAGTG
ACTATATTTCTTTTTACGAAAATGCTATTTTTCTATGATGTAAACAATTGTTAGGCGGCAGATTTTTAAGGAAGTATTATTTTATTTAAGAGTCTGTATC
CCTTTGTGTGAGAGGAACCCAAAGAGGGTTCACTTTTGCTTTAAAGCTCTGTCCCTTACCCACTGACAACTCTGCTACTTTTATTTTATCTTAGAAAATG
TCAATATAGACATATCACAGGGTTAATAAAAGAAACTTTTCACAAAGATTTTTGTACAAGTGTAGCTATCAGGTTATATTTGAAAATAACCCTCTGAAAA
CCAGCCAACATTGTCATGACAATTTTTGCTGCCGTATCAACTAGAATTACCAAAAAACATAGTTTTATCTTTGTATGTGTGTGGGGATCTACCCTGAGAC
CATGCTTTTCTTCCCACCCTGCCACCCCACCCCTTTAAAGAAATACGTATTTTTATCTAGAATGATCTTGAATTAGTCTCTGCATATTTTTAGAAAGTGC
TTGGGGACATTATATATATGCCATTACAAAAGCATTATGAGGCCTATGTATTCTACTGTGTTTAATACTGCATTAACCTGCACAAAGTTTATGCATTTTT
TCATGCATTTTTTTCCTTCTTTCTAAGTAAGGTATTCCTGACAACTAACATTCCCTAAATCATTTCCCCTCCCTCCCTCCCTCCCTCCCTTCCTTTCTTC
CTTCCTTCTGTCCTCCCTCCCTTGCTACCTCTTGCCCTCCTTCCTTCACCCTGTCCTCCTTTTCCCTTTTATTTTTTCCCCTTCTCTTTCATTTTATTTT
CTTTTAGAGAAACCACCTTATCTATTTTTAGACATTTCGAATTCCTAAAATGTGAACCGTTGGGTGATCTGTCCTTTGGCCCTAAAACGGCTGGCCGGGC
TGTCCCGGCCTGTTCTCATCTGTACCGTATGATTTTATTTCATAATAACTTTATGTATTTGGACTGTAACAAACAAAACAGAACCTAAGTCGCCCCGAAA
AATCTTTCCAAGCCTTTTCAAAACACTTATCTGCAGTCCAGAATTCAGCTCTTATGAAAAGTGAGAGTGCACTCCAGTTTTCACAGCAGCAATAAGTGCG
GGAAACAAAAAGATCCTCTTCCCAGGAAAAGTTGAGTGGGGAAGAGTTCAGACACTGTTGTAGCTGGTGAATCATTGAAGTCACCTGGTAGTACCAAATA
AGGGCTGAGGCGCCTGGAGGTCTTTGTGGGGTCTTCCCTCTTTAAATGCAAACGTAAGAAGGTATATGTGTATATACATTTATATACGTGCACATGTATA
CTCGTACATGTATGCACACATACCCATACATGTATATGAACTCCGTTCTGATTTCCTCTGAAATTTTGTTGATACCATCTAAATACCTCTTTGAATCAAA
ATAACTTAATTTTAGCTCATTCCTCAAGAGAAAGAGAAGGATCCCCAAGGAAGAAAAACTGTTGTACCTTCTGTGATTCTCAAACCAAAATGTGATGCGC
TTCTGTTTTGTTATCTTAAATTGTTGTATCATATCTTTCTGAAACCATTCTGAATTAAGTTGAAATTTTCAACATTTATACTTTAACTGTTCTAAATTTA
AGCCTACATGTAAATCTTTTTTGGGGGGAAGGTAACTTGAAAAGTTTAACTTGAAAATTTGACCTTTAAACTTTCATATTCTAAGGTAAATAATAGCCTA
TAACCAACAACAGCTTTCCCAGAGGTCTTGAATTTAACACTAATTGTTTAGTTATTGTTTCTATTTCTCATACATACATAACTTCGTTTTTTGTGGCTGG
AAGAAAAAGTTTCTATATTTTGTATTTGTCTTTGTTCTTCTCATGCACACAATTTACTGTTGGTGTTTAATAATTTGGAGCTCATAAAATTAAAAGTTGT
AATTTTGACCATTTGGGCTAAAAATTATATGAGGGATTACATATGCAATGGATTAGTATTTCTTGATTTGCAAAAGAAGGGAAAATGATGGTAATTTAGC
TCAAATTGCCTTTCTTTGAAGAAAATTTCTGAATGACTGAAAACCAAATATCTATATTATCACTTTCAACCTCATGTTTCTGCAAAGTACAGAAAAACTC
CTCACTGACAGTGCACCCAGCCCCTGACTGGGTTTTCAGGATTATGTCCATGTGCATAACTGCTTGGATTTCTTCTTTTAAAGTCCCTAAAACATGAATC
TGTTCTTTGAGATCCTGGTTTCCTTAGCAGAGTTGTAGGTTGCGGGTTTCATTCACGTGGAAATTCTAAGTAGAACTTTTGCTGCCCCATTTTACTGTTG
GTGAAGGGCCGTTGTTAATGGAAGTTTACGTTTTAAAACTCAGATGACTCAGAAACCAGACTGTGATCATTTTTTGCAGCAGCAAAATGACTTATTCTGA
CAGCATCTCGGTTTGGGGCTTCTGAAGAAAAAGGATGAAGCTGATCTGTTGAAACAACTACTTTCCCAACTCGGAGGCAAAAGGGGCTGATAGAAGATAA
CATTCACCTACCATTTCATCTTGTGACCCCCAGAGATCACGTTTGCGTGTTCTGGCTGAGTTTTTTATTATTGTTTGTTTTAAATGATTAAATAATACAC
AATTAAATGTCAGGATAGCATCTCTTGCAAAGTGACCAGTGCAGCAGAATTGTCTTTCTATCCATATTTGAGCTTAGAGAAACATTTCCCATGTCCTAAG
TTCTTAGAAGCAATTACTTTAGCGTTGGGGAGCATTGTTCTACCAGACCCATTTATGCAGGGGAGATGAAGCTTAAAAGACGGGATGTGGGGTGGGAGTG
TGTTTCTTAAGCCGAAGCTGTTGCAGGCTGGGGGATTTTTGCATTTTCTTTTTGTTTTGTTTTTGACTGCAGATTCTGTACATCTGTCTGTGGGAGGAGA
GTTGCTACTCAGGACAGGATTTAAGAGACACATTCCAGTGACCTTTAAGAATCTGCATGGCGGGAGGTCCTTCTCCAGGAGTGTGGGTTGGTCCACTCTG
GGACCCACCACACTAAGAAGGGGGAGATGATAAAATAACATTAAAGGAAGAATGGCCTCCAGCCTGCAGGTTTTGTTGGAAAGAAATAAAAAGGGAGTCA
TTAAGACCATAAATTCAGATTGAGGCCTCTTGAAAAGGTTGATGTGGGCTAGCAACCTGCCTGTCGAAACAGTCCTTGGTTCATCAGCAGTGTGGGAAGG
CAGCCAAGGCTCCTGCAGATTCCTGGCATCGACCTTGGAAAGCCTCTGCGATACTTGTGTGTACGAATACAGCAGAGGACAGGGAGGTCCTTGTTCTGTG
GTCTCTGTTTAGTGACTGAAACTTAAACCCAAAGGCAAGCCCAGATTGTCTGGCCGTTCATCCCCATGCTTTGATAGGGGTTAGGAGGAACCCTTTCCGT
ATGAAAGACAGGCCCTACTAGGGCTTACAACCAAGCCAAAGGACCATCTCTTCTTTCTTCCACCTCCCTTCACCCCTGCCCCGCAGCAGAGCCGAGATGT
GAGACATTCATTGTCACGGAGCAAGGAGACAAAGGCAAGTTCAAGTTGAGAAGCATATGGCAGCAAACAGAAATGAAAACCATATGTCCCAGCAAGGGGA
AAAGCAGTCATTTCCAGATTATAAAAATCAATGAAGTACTCTCCACCTAGGTCAGCTGAAATTCGAGCCCTCACAGTCAGGCCTGTCAGAGAAGTTAAGC
AGAAACATCTCGGGGGGACTTCTAAAATTTAGTGAAGACAAGGCCTTGCAACTCCAAAGAAACTTTTTTTCCCCCCCTTGAAACAGGGTCTTGCTCTGTT
GCCCAGCCTGGAGTGCAGTGGTGCAGTCACGGCTCACTGCAGCCTCAAGCTCCTGGGCTCAAGCACTATCCCCACCTCAACCTCCTTAGTAGCTGGGACT
ACAGGTGCACACCACCATGCCCAGCTAACCACAGAAACTTTCATCTCTTCATTTTTTCTTTGGGCACCATTAATACCTAAGACAGGTAGAAAGGGTCCCA
GAAAGACACCATTGGTAATGGCCGATTGCCGGCTGCAGTCATCGCCCCCAGATCAGGCTGGTACAGGATGCCTTAAGGTGATGAGAGGTGAGGGTGCATG
AAGAATAATGAGCACAGGGAAGAGAGAAGCAGGACAAAGTAGCAGATAAAATGCCGGCAAAGCACAGATGAATGTCTTCAAGAAGCTCTTGTATTTCTCT
GCACAGTGTAAATATCCTTGCTATTTCAGGATGGCGGCTGGCCTGCTCAGTAACATACATGTTCCAAATAAAGATTTTGCATGAAAGTA
  • refseq_KIAA1462.F2 (forward primer)
  • refseq_KIAA1462.R2 (reverse primer)
  • Single exon skipping

Frame 0

ELKLRAAIGGGF*I*EILSRASEGLLKNSIL*T
LMKKSGISSVLGPATTMVPVVELC*SPGIMYSVE
DLLISHGYKLSRDPPASREDNPKGRQAARTGTR
AGQGLQNGHEDGPAALAHRKTSAGKGHVSDSES
R
RSTPRGHGEPQSTSASRTSEAGCPIEN*KLEGN
RK
VL*STPLSMVLSSPDW*RPSLPEKRTARSQE
PEAEGARKPGGQRNGPSPQPACPREGGSMGSWR
KVRACDEEASLGRRIANVRSCQVAERQPGKLEPA
KEIREADV*WRWGETVSRPVPIHSRRTCVEFSK
QREVSLTA*SSFPREPELHGNSHSIK*KTFT*N
ATVSSHLRTKFGLHEEF*EEWLLSPISPA*VWEA
PQAPILQLAPAV*GRSGQQ*LSGQPADGRLCPQ
A*ALPVRPWIGTSSVRASALIQIAPAEHPKPLL
GRHGAHKCVWRSQSTAVSDREGWGQRSASFRPPW
NWE*VWCEPPLASGAPRTSPTCHCL*RLRSVHS
L**STVTTF*TSSAPGFL*RHKA*R*II*LQSC
HCSRAGSWRNAA*WCHLESTELNTPVGG*ERPGL
GRFQPPVAVGPAPRGWGKQWPPQPERPLCGKGT
VA*CERQPARAHWKTSFLPLLTGREHLRNSNQA
QKVPNWDSDQEKFKEKNERDYILLGFYPSEIRIT
SAR*RYGQQ*LKAQC*SKEWV**EPGSARTESA
EHVFHRPGAAGPHRKHGWENGVPKTRSRGTRRR
QTNK*PQFHPPYKAQRTQAFWLLARAPVQRSANT
NQFLRGAPKFAAAPWCKAGRAESCSIESKMFRP
CCLRSSDAHSIPYR*SQTEAKCP*PERSQVPQP
IQQQCVLKDFLVRGPGTDAKSRPKSALRGCPRAW
SPPWA*AGGGEGGAHGPLQQ*TTLWAVSPETGQ
PSSLGFDQSVRKF*QGAPGRGRKQQ*QQQQQQQ
Q*GE*GGAAAGEPCSLQTGGCGLPRKQPGNEG*A
TAEDVGAGEPCV*VGKR*E*V*ELE*GAAAWPP
TCLASIPGPLSRGRRWRCTFLLSRWKHECREET
PGG*QRNGRAGR*PISCDENVFKIK*RKTTARVL
SS*T*GAPGKSENHQCFQLCETK*SGPSEV*QW
WREGGRAPTVPV*QEPRALSSRLTVCGAHPWAR
TGCQ*ARGVFG*SKHNRNPPR*VLASQGCKDPGH
*GGGGVPPAGHPESGTEPAC*ARCKCLHPRVPP
GRVAISPSTGRCPQGVH*CLLWQEEVRLDQEPS
LCRGQGQCQAGSSGF*ALRCGRGCHQHRPCP*A*
AQPLGVQVLRTKGCGNKTTLQVHFIPFCRKNPK
CGRL*KET*KPFQSD*KFTRETGLPA*ESRP*P
PDENERGELSVTDESPELQECRLPGGRRGIEGHH
KGPGRAPGRPCVSWQWGPCPEIGPLTLCVQGQH
LQGREGASGSTKGEEHGSRLLVPRFL*P*QSGE
GVMKCRWSLHSVAN*VFSSSW*I*SISPTSPCRS
WKLLSF*HPDNILYHCH*ETCHPLRIALWR*SN
RPLKPSVFIA*RFNAYN*EGVFTETLPHDRFD*
AGK*FGVALILGEDFNVEDLANALERPVNGVLPS
VSPWPAVHALVKEFGTLAVARCFSTFSLGEM*I
NRYDPFLINLAFCCWK*LYL*VTCHQRIKAISF
KFLKN*NLYCNILRVLFIWQ*NILIICKHAIVCF
ALSIIYFYFLYGYLEILYMKNNCWFKIDHFNKV
TIFLFTKMLFFYDVNNC*AADF*GSIILFKSLY
PFV*EEPKEGSLLL*SSVPYPLTTLLLLFYLRKC
QYRHITGLIKETFHKDFCTSVAIRLYLKITL*K
PANIVMTIFAAVSTRITKKHSFIFVCVWGSTLR
PCFSSHPATPPL*RNTYFYLE*S*ISLCIFLESA
WGHYIYAITKAL*GLCILLCLILH*PAQSLCIF
SCIFFLLSK*GIPDN*HSLNHFPSLPPSLPSFL
PSFCPPSLATSCPPSFTLSSFSLLFFPLLFHFIF
F*RNHLIYF*TFRIPKM*TVG*SVLWP*NGWPG
CPGLFSSVPYDFIS**LYVFGL*QTKQNLSRPE
KSFQAFSKHLSAVQNSALMKSESALQFSQQQ*VR
ETKRSSSQEKLSGEEFRHCCSW*IIEVTW*YQI
RAEAPGGLCGVFPL*MQT*EGICVYTFIYVHMY
TRTCMHTYPYMYMNSVLISSEILLIPSKYLFESK
*LNFSSFLKRKRRIPKEEKLLYLL*FSNQNVMR
FCFVILNCCIISF*NHSELS*NFQHLYFNCSKF
KPTCKSFLGGR*LEKFNLKI*PLNFHILR*IIAY
NQQQLSQRS*I*H*LFSYCFYFSYIHNFVFCGW
KKKFLYFVFVFVLLMHTIYCWCLIIWSS*N*KL
*F*PFGLKII*GITYAMD*YFLICKRRENDGNLA
QIAFL*RKFLND*KPNIYIITFNLMFLQSTEKL
LTDSAPSP*LGFQDYVHVHNCLDFFF*SP*NMN
LFFEILVSLAEL*VAGFIHVEILSRTFAAPFYCW
*RAVVNGSLRFKTQMTQKPDCDHFLQQQNDLF*
QHLGLGLLKKKDEADLLKQLLSQLGGKRG**KI
TFTYHFIL*PPEITFACSG*VFYYCLF*MIK*YT
IKCQDSISCKVTSAAELSFYPYLSLEKHFPCPK
FLEAITLALGSIVLPDPFMQGR*SLKDGMWGGS
VFLKPKLLQAGGFLHFLFVLFLTADSVHLSVGGE
LLLRTGFKRHIPVTFKNLHGGRSFSRSVGWSTL
GPTTLRRGR**NNIKGRMASSLQVLLERNKKGV
IKTINSD*GLLKRLMWASNLPVETVLGSSAVWEG
SQGSCRFLASTLESLCDTCVYEYSRGQGGPCSV
VSV**LKLKPKGKPRLSGRSSPCFDRG*EEPFP
YERQALLGLTTKPKDHLFFLPPPFTPAPQQSRDV
RHSLSRSKETKASSS*EAYGSKQK*KPYVPARG
KAVISRL*KSMKYSPPRSAEIRALTVRPVREVK
QKHLGGTSKI**RQGLATPKKLFFPPLKQGLALL
PSLECSGAVTAHCSLKLLGSSTIPTSTSLVAGT
TGAHHHAQLTTETFISSFFLWAPLIPKTGRKGP
RKTPLVMADCRLQSSPPDQAGTGCLKVMRGEGA*
RIMSTGKREAGQSSR*NAGKAQMNVFKKLLYFS
AQCKYPCYFRMAAGLLSNIHVPNKDFA*K

Frame 1

SSNLELLSEEDFRFRKFSAEHPRGF*KIQFFRR
S*RNQGFPQCWVLPPPWFQWLSFAEAQASCTV*
KTS*SLMDTSCQETPQHHARITPRGARQRGLGHE
QARACRTGMRMALRPSHIVRRPRGKDM*VTPKA
A
AAHREATGSPRALLLPEPRRRGAQ*RTENWRE
TER
FCNQPPSAWSSHPPTGNDQAYRRRGRQEARS
QKPREHENLEARGMAQAHSLPVHVREGPWEVGG
RSEHVMKKPVWEEELRMSGPAKWQNVSLESWNQ
PRKLGRQMSDGDGERLFQDLYPFIQGEHVLNSQN
KGKSRSLPRVLSPESLSCTEIPIPLNERHSPKM
PPYPPTCAPNLDSTRNSEKSGCSAPFPRPKFGR
PLKPPSYSSHQQSRGGADSSDSQDSQQMDAYVPR
HELCLSDPGLEPPVYVPPPSYRSPPQNIPNPYL
EDTVPINVCGGHSQQQSPTEKAGASGQPPSGPP
GTGNEYGVSPRLPQGLPAHPRPVTAYDGFVQYIP
FDDPRLRHFKLAQPQGFCEDIKLDDKSYNSSPV
TAQEPAHGGMQPDGAIWNPQSLIPPSGDERGLV
LADSSPRWLWGQPPGDGENSGLPNQRDRCVARGQ
WPDVRGSQHGHTGRQVSSPYSQGESTCETQTKL
KKFQTGTRTKKSSKKKMNETIFCLVSIPVKSES
HLPDRDMDNNDLKPSADQKNGSDKSPALQEQSLL
SMSSTDLELQALTGSMGGRTEFQKQDLGEPEED
RQTNDLSFIHLTKHRELKHSGSWPGHRYRDQQT
QTSFSEEPQSSQLLPGAKLGGPSRAALSPKCSDP
AASEAQTHTAFPTGDHKQRPSARNLKGHRSLSP
SSNSAFSRTSLSVDQAPTPKAGRSQPCVDVHGL
GAHPGPKREVVKGEPTGPCNSKQLFGQFLLKPVS
RRPWDLISQLESFNKELQEEEESSSSSSSSSSS
SEESEAEPQQENRAHCRQEDVGFRGNSPEMRVE
PQPRMWVPESPVCRSGRGESKSESWSEELQPGHP
RAWPPSPGRFRVEEGGGAPFCSADGSTSAEKRH
LEVSNGMDELAGSPFPVTRMSSRSSDAKPLPAS
YPAEPREPQESPKITSAFSSVKPSEAVPRKFDSG
GERGAGLPLSLSNKNRGLSAPDLRSVGLTPGQE
QGASELEGSLGEASTIEIPPGESLQARAARILG
IEVAVESLLPGIRRAGQNQPAEPDASACTPESPQ
EELLSRPAPADVPRVSTDAFYGRRKCGWTKSPL
FVGDRDSARRAPQAFEHSDVDGVVTSTDPVPEP
EPSPLESKFFEQKDVETKPPFRSTLFHFVERTPS
VAGSEKRLRSPSKVIESLQEKLASPPRRADPDR
LMRMKEVSSVSRMRVLSFRNADSQEDAEELKAT
TRGQAGLPGGLVSPGSGDRAQRLGHSLSVSKDSI
SREEKEHPAAQKEKSMDQDFWCPDSYDPSRVER
V**NAGGACIPLRIEYSQVAGRFSLSAPLPHVE
AGSC*VFSILITFFTTATRKLAILSELLCGDKAI
VR*NHLFL*HEDLMPIIRKEFSQKPSLMTDLTK
LVNSLVLLSFWVKISMWKI*QMLWKGL*MVCSP
LCLHGLQSMLL*RSLGHWLLPGVSALSV*GKCES
IGMIHF*SIWPSAAGSNFTYK*LAIRE*KQYLL
SS*KIKTCTVIY*EYYLSGSEIF*SFANTPLSA
LHSVLSIFIFCMGI*KFFI*KIIAGLK*TILTK*
LYFFLRKCYFSMM*TIVRRQIFKEVLFYLRVCI
PLCERNPKRVHFCFKALSLTH*QLCYFYFILEN
VNIDISQG**KKLFTKIFVQV*LSGYI*K*PSEN
QPTLS*QFLLPYQLELPKNIVLSLYVCGDLP*D
HAFLPTLPPHPFKEIRIFI*NDLELVSAYF*KV
LGDIIYMPLQKHYEAYVFYCV*YCINLHKVYAFF
HAFFSFFLSKVFLTTNIP*IISPPSLPPSLPFF
LPSVLPPLLPLALLPSPCPPFPFYFFPFSFILF
SFRETTLSIFRHFEFLKCEPLGDLSFGPKTAGRA
VPACSHLYRMILFHNNFMYLDCNKQNRT*VAPK
NLSKPFQNTYLQSRIQLL*KVRVHSSFHSSNKC
GKQKDPLPRKS*VGKSSDTVVAGESLKSPGSTK*
GLRRLEVFVGSSLFKCKRKKVYVYIHLYTCTCI
LVHVCTHTHTCI*TPF*FPLKFC*YHLNTSLNQ
NNLILAHSSREREGSPRKKNCCTFCDSQTKM*CA
SVLLS*IVVSYLSETILN*VEIFNIYTLTVLNL
SLHVNLFWGEGNLKSLT*KFDL*TFIF*GK**P
ITNNSFPRGLEFNTNCLVIVSISHTYITSFFVAG
RKSFYILYLSLFFSCTQFTVGV**FGAHKIKSC
NFDHLG*KLYEGLHMQWISIS*FAKEGKMMVI*
LKLPFFEENF*MTENQISILSLSTSCFCKVQKNS
SLTVHPAPDWVFRIMSMCITAWISSFKVPKT*I
CSLRSWFP*QSCRLRVSFTWKF*VELLLPHFTV
GEGPLLMEVYVLKLR*LRNQTVIIFCSSKMTYSD
SISVWGF*RKRMKLIC*NNYFPNSEAKGADRR*
HSPTISSCDPQRSRLRVLAEFFIIVCFK*LNNT
QLNVRIASLAK*PVQQNCLSIHI*A*RNISHVLS
S*KQLL*RWGALFYQTHLCRGDEA*KTGCGVGV
CFLSRSCCRLGDFCIFFLFCF*LQILYICLWEE
SCYSGQDLRDTFQ*PLRICMAGGPSPGVWVGPLW
DPPH*EGGDDKITLKEEWPPACRFCWKEIKRES
LRP*IQIEAS*KG*CGLATCLSKQSLVHQQCGK
AAKAPADSWHRPWKASAILVCTNTAEDREVLVLW
SLFSD*NLNPKASPDCLAVHPHALIGVRRNPFR
MKDRPY*GLQPSQRTISSFFHLPSPLPRSRAEM
*DIHCHGARRQRQVQVEKHMAANRNENHMSQQGE
KQSFPDYKNQ*STLHLGQLKFEPSQSGLSEKLS
RNISGGLLKFSEDKALQLQRNFFSPP*NRVLLC
CPAWSAVVQSRLTAASSSWAQALSPPQPP**LGL
QVHTTMPS*PQKLSSLHFFFGHH*YLRQVERVP
ERHHW*WPIAGCSHRPQIRLVQDALR**EVRVH
EE**AQGREKQDKVADKMPAKHR*MSSRSSCISL
HSVNILAISGWRLACSVTYMFQIKILHES

Frame 2

AQT*SCYRRRILDLGNSQQSIRGAFEKFNSLDA
HEEIRDFLSAGSCHHHGSSG*ALLKPRHHVQCR
RPPDLSWIQAVKRPPSITRG*PQGAPGSEDWDT
SRPGPAERA*GWPCGPRTS*DVRGERTCE*LRKP
PQHTERPRGAPEHFCFQNLGGGVPNRELKIGGK
QK
GFVINPPQHGPLIPRLVTTKPTGEEDGKKPG
ARSRGSTKTWRPEEWPKPTACLST*GRVHGKLEE
GQSM**RSQFGKKNCECQVLPSGRTSAWKAGTS
QGN*GGRCLMEMGRDCFKTCTHSFKENMC*ILK
TKGSLAHCLEFFPPRA*VARKFPFH*MKDIHLKC
HRILPLAHQIWTPRGILRRVAAQPHFPGLSLGG
PSSPHLTARTSSLGEERTAVTLRTASRWTPMSP
GMSSACQTLDWNLQCTCLRPHTDRPRRTSQTPTW
KTRCP*MCVAVTVNSSLRPRRLGPAVSLLQAPL
ELGMSMV*APACLRGSPHIPDLSLPMTASFSTF
PLMIHGYDILN*LSPRVSVKT*SLTINHITPVLS
LLKSRLMEECSLMVPFGIHRA*YPRRGMREAWS
WPIPAPGGCGASPPGMGKTVASPTRETAVWQGD
SGLM*EAASTGTLEDKFPPLTHRARAPAKLKPSS
KSSKLGLGPRKVQRKK*TRLYFAWFLSQ*NQNH
ICQIEIWTTMT*SPVLIKRMGLIRARLCKNRVC
*ACLPPTWSCRPSQEAWVGERSSKNKI*GNQKKT
DKQMTSVSSTLQSTENSSILALGQGTGTEISKH
KPVSPRSPKVRSCSLVQSWEGRVVQH*VQNVQT
LLPPKLRRTQHSLPVITNRGQVPVT*KVTGPSAH
PATVRSQGLPCPWTRHRRQKQAEVSPAWMSTGL
EPTLGLSGRW*RGSPRALATVNNSLGSFS*NRS
AVVPGI*SVS*KVLTRSSRKRKKAAVAAAAAAAA
VRRVRRSRSRRTVLTADRRMWASAETARK*GLS
HSRGCGCRRALCVGREEVRVSLRAGVRSCSLAT
HVPGLHPRAAFAWKKVAVHLSAQQMEARVQRRDT
WRLATEWTSWQVAHFL*RECLQDQVTQNHCPRP
IQLNLGSPRKVRKSPVLSAL*NQVKRSLGSLTV
VERGGQGSHCPCLTRTEGSQLQTYGLWGSPLGKN
RVPVS*RGLWVKQAQ*KSPQVSPCKPGLQGSWA
LRWRWSPSCRASGERDRTSLLSPMQVPAPQSPP
RKSCYLAQHRQMSPGCPLMPFMAGGSAAGPRALS
L*GTGTVPGGLLRLLSTQMWTGLSPAQTLSLSL
SPAPWSPSSSNKRMWKQNHPSGPLYSIL*KEPQ
VWQALKRDLEALPK*LKVYKRNWPPRLGEQTLTA
**E*KR*AQCHG*ES*ASGMPTPRRTPRN*RPP
QGARPGSREALCLLAVGTVPRDWATHSLCPRTA
SPGKRRSIRQHKRRRAWIKTSGAQIPMTLAEWRG
CDEMPVELAFRCELSILK*LVDLVYQPHFPM*K
LEAAEFLAS**HSLPLPLGNLPSSQNCFVAIKQ
SSVETICFYSMKI*CL*LGRSFHRNPPS*QI*LS
W*IVWCCSHSG*RFQCGRSSKCFGKACEWCAPL
CVSMACSPCSCEGVWDTGCCPVFQHFQFRGNVN
Q*V*SISNQFGLLLLEVTLLISNLPSENKSNIF*
VPEKLKLVL*YTKSIIYLAVKYFDHLQTRHCLL
CTQYYLFLFSVWVFRNSLYEK*LLV*NRPF*QS
DYISFYENAIFL*CKQLLGGRFLRKYYFI*ESVS
LCVRGTQRGFTFALKLCPLPTDNSATFILS*KM
SI*TYHRVNKRNFSQRFLYKCSYQVIFENNPLK
TSQHCHDNFCCRIN*NYQKT*FYLCMCVGIYPET
MLFFPPCHPTPLKKYVFLSRMILN*SLHIFRKC
LGTLYICHYKSIMRPMYSTVFNTALTCTKFMHF
FMHFFPSF*VRYS*QLTFPKSFPLPPSLPPFLSS
FLLSSLPCYLLPSFLHPVLLFPFIFSPSLSFYF
LLEKPPYLFLDISNS*NVNRWVICPLALKRLAG
LSRPVLICTV*FYFIITLCIWTVTNKTEPKSPRK
IFPSLFKTLICSPEFSSYEK*ECTPVFTAAISA
GNKKILFPGKVEWGRVQTLL*LVNH*SHLVVPN
KG*GAWRSLWGLPSLNANVRRYMCIYIYIRAHVY
SYMYAHIPIHVYELRSDFL*NFVDTI*IPL*IK
IT*F*LIPQEKEKDPQGRKTVVPSVILKPKCDA
LLFCYLKLLYHIFLKPF*IKLKFSTFIL*LF*I*
AYM*IFFGGKVT*KV*LENLTFKLSYSKVNNSL
*PTTAFPEVLNLTLIV*LLFLFLIHT*LRFLWL
EEKVSIFCICLCSSHAHNLLLVFNNLELIKLKVV
ILTIWAKNYMRDYICNGLVFLDLQKKGK*W*FS
SNCLSLKKISE*LKTKYLYYHFQPHVSAKYRKT
PH*QCTQPLTGFSGLCPCA*LLGFLLLKSLKHES
VL*DPGFLSRVVGCGFHSRGNSK*NFCCPILLL
VKGRC*WKFTF*NSDDSETRL*SFFAAAK*LIL
TASRFGASEEKG*S*SVETTTFPTRRQKGLIEDN
IHLPFHLVTPRDHVCVFWLSFLLLFVLND*IIH
N*MSG*HLLQSDQCSRIVFLSIFELRETFPMS*
VLRSNYFSVGEHCSTRPIYAGEMKLKRRDVGWEC
VS*AEAVAGWGIFAFSFCFVFDCRFCTSVCGRR
VATQDRI*ETHSSDL*ESAWREVLLQECGLVHS
GTHHTKKGEMIK*H*RKNGLQPAGFVGKK*KGSH
*DHKFRLRPLEKVDVG*QPACRNSPWFISSVGR
QPRLLQIPGIDLGKPLRYLCVRIQQRTGRSLFC
GLCLVTET*TQRQAQIVWPFIPML**GLGGTLSV
*KTGPTRAYNQAKGPSLLSSTSLHPCPAAEPRC
ETFIVTEQGDKGKFKLRSIWQQTEMKTICPSKG
KSSHFQIIKINEVLST*VS*NSSPHSQACQRS*A
ETSRGDF*NLVKTRPCNSKETFFPPLETGSCSV
AQPGVQWCSHGSLQPQAPGLKHYPHLNLLSSWD
YRCTPPCPANHRNFHLFIFSLGTINT*DR*KGSQ
KDTIGNGRLPAAVIAPRSGWYRMP*GDER*GCM
KNNEHREERSRTK*QIKCRQSTDECLQEALVFL
CTV*ISLLFQDGGWPAQ*HTCSK*RFCMKV

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