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Sequences

Sequence NM_053029

GGCGCTGAGCGAGCTCGGAGCCCGCGCTGTGCGCCTGCGGCCGGGGCGCCCCGCCGAGCGCCGGTGCCCCGGCTCCCGGGCCGCCTTCGCCGCGCGGGAA
GGATTCTTCAAAATTAACAGAAACCAATTCGGGCCAGCTGAAGAGAAAAAATAAAGGTGGCTCCCGGCTGCCTCTGCTGCAGTTCAGAGCAACTTCAGGA
GCTTCCCAGCCGAGAGCTTCAGGACGCCTTTCCTGTCCCACTGGCCCAGTTGCCACAACAAACAACAGAGAAGACGGTGACCATGGGGGATGTGAAGCTG
GTTGCCTCGTCACACATTTCCAAAACCTCCCTCAGTGTGGATCCCTCAAGAGTTGACTCCATGCCCCTGACAGAGGCCCCTGCTTTCATTTTGCCCCCTC
GGAACCTCTGCATCAAAGAAGGAGCCACCGCCAAGTTCGAAGGGCGGGTCCGGGGTTACCCAGAGCCCCAGGTGACATGGCACAGAAACGGGCAACCCAT
CACCAGCGGGGGCCGCTTCCTGCTGGATTGCGGCATCCGGGGGACTTTCAGCCTTGTGATTCATGCTGTCCATGAGGAGGACAGGGGAAAGTATACCTGT
GAAGCCACCAATGGCAGTGGTGCTCGCCAGGTGACAGTGGAGTTGACAGTAGAAGGAAGTTTTGCGAAGCAGCTTGGTCAGCCTGTTGTTTCCAAAACCT
TAGGGGATAGATTTTCAGCTCCAGCAGTGGAGACCCGTCCTAGCATCTGGGGGGAGTGCCCACCAAAGTTTGCTACCAAGCTGGGCCGAGTTGTGGTCAA
AGAAGGACAGATGGGACGATTCTCCTGCAAGATCACTGGCCGGCCCCAACCGCAGGTCACCTGGCTCAAGGGAAATGTTCCACTGCAGCCGAGTGCCCGT
GTGTCTGTGTCTGAGAAGAACGGCATGCAGGTTCTGGAAATCCATGGAGTCAACCAAGATGACGTGGGAGTGTACACGTGCCTGGTGGTGAACGGGTCGG
GGAAGGCCTCGATGTCAGCTGAACTTTCCATCCAAGGTTTGGACAGTGCCAATAGGTCATTTGTGAGAGAAACAAAAGCCACCAATTCAGATGTCAGGAA
AGAGGTGACCAATGTAATCTCAAAGGAGTCGAAGCTGGACAGTCTGGAGGCTGCAGCCAAAAGCAAGAACTGCTCCAGCCCCCAGAGAGGTGGCTCCCCA
CCCTGGGCTGCAAACAGCCAGCCTCAGCCCCCAAGGGAGTCCAAGCTGGAGTCATGCAAGGACTCGCCCAGAACGGCCCCGCAGACCCCGGTCCTTCAGA
AGACTTCCAGCTCCATCACCCTGCAGGCCGCAAGAGTTCAGCCGGAACCAAGAGCACCAGGCCTGGGGGTCCTATCACCTTCTGGAGAAGAGAGGAAGAG
GCCAGCTCCTCCCCGTCCAGCCACCTTCCCCACCAGGCAGCCTGGCCTGGGGAGCCAAGATGTTGTGAGCAAGGCTGCTAACAGGAGAATCCCCATGGAG
GGCCAGAGGGATTCAGCATTCCCCAAATTTGAGAGCAAGCCCCAAAGCCAGGAGGTCAAGGAAAATCAAACTGTCAAGTTCAGATGTGAAGTTTCCGGGA
TTCCAAAGCCTGAAGTGGCCTGGTTCCTGGAAGGCACCCCCGTGAGGAGACAGGAAGGCAGCATTGAGGTTTATGAAGATGCTGGCTCCCATTACCTCTG
CCTGCTGAAAGCCCGGACCAGGGACAGTGGGACATACAGCTGCACTGCTTCCAACGCCCAAGGCCAGCTGTCCTGTAGCTGGACCCTCCAAGTGGAAAGG
CTTGCCGTGATGGAGGTGGCCCCCTCCTTCTCCAGTGTCCTGAAGGACTGCGCTGTTATTGAGGGCCAGGATTTTGTGCTGCAGTGCTCCGTACGGGGGA
CCCCAGTGCCCCGGATCACTTGGCTGCTGAATGGGCAGCCCATCCAGTACGCTCGCTCCACCTGCGAGGCCGGCGTGGCTGAGCTCCACATCCAGGATGC
CCTGCCGGAGGACCATGGCACCTACACCTGCCTAGCTGAGAATGCCTTGGGGCAGGTGTCCTGCAGCGCCTGGGTCACCGTCCATGAAAAGAAGAGTAGC
AGGAAGAGTGAGTACCTTCTGCCTGTGGCTCCCAGCAAGCCCACTGCACCCATCTTCCTGCAGGGCCTCTCTGATCTCAAAGTCATGGATGGAAGCCAGG
TCACTATGACTGTCCAAGTGTCAGGGAATCCACCCCCTGAAGTCATCTGGCTGCACAATGGGAATGAGATCCAAGAGTCAGAGGACTTCCACTTTGAACA
GAGAGGAACTCAGCACAGCCTTTGTATCCAGGAAGTGTTCCCGGAGGACACGGGCACGTACACCTGCGAGGCCTGGAACAGCGCTGGAGAGGTCCGCACC
CAGGCCGTGCTCACGGTACAAGAGCCTCACGATGGCACCCAGCCCTGGTTCATCAGTAAGCCTCGCTCAGTGACAGCCTCCCTGGGCCAGAGTGTCCTCA
TCTCCTGCGCCATAGCTGGTGACCCCTTTCCTACCGTGCACTGGCTCAGAGATGGCAAAGCCCTCTGCAAAGACACTGGCCACTTCGAGGTGCTTCAGAA
TGAGGACGTGTTCACCCTGGTTCTAAAGAAGGTGCAGCCCTGGCATGCCGGCCAGTATGAGATCCTGCTCAAGAACCGGGTTGGCGAATGCAGTTGCCAG
GTGTCACTGATGCTACAGAACAGCTCTGCCAGAGCCCTTCCACGGGGGAGGGAGCCTGCCAGCTGCGAGGACCTCTGTGGTGGAGGAGTTGGTGCTGATG
GTGGTGGTAGTGACCGCTATGGGTCCCTGAGGCCTGGCTGGCCAGCAAGAGGGCAGGGTTGGCTAGAGGAGGAAGACGGCGAGGACGTGCGAGGGGTGCT
GAAGAGGCGCGTGGAGACGAGGCAGCACACTGAGGAGGCGATCCGCCAGCAGGAGGTGGAGCAGCTGGACTTCCGAGACCTCCTGGGGAAGAAGGTGAGT
ACAAAGACCCTATCGGAAGACGACCTGAAGGAGATCCCAGCCGAGCAGATGGATTTCCGTGCCAACCTGCAGCGGCAAGTGAAGCCAAAGACTGTGTCTG
AGGAAGAGAGGAAGGTGCACAGCCCCCAGCAGGTCGATTTTCGCTCTGTCCTGGCCAAGAAGGGGACTTCCAAGACCCCCGTGCCTGAGAAGGTGCCACC
GCCAAAACCTGCCACCCCGGATTTTCGCTCAGTGCTGGGTGGCAAGAAGAAATTACCAGCAGAGAATGGCAGCAGCAGTGCCGAGACCCTGAATGCCAAG
GCAGTGGAGAGTTCCAAGCCCCTGAGCAATGCACAGCCTTCAGGGCCCTTGAAACCCGTGGGCAACGCCAAGCCTGCTGAGACCCTGAAGCCAATGGGCA
ACGCCAAGCCTGCCGAGACCCTGAAGCCCATGGGCAATGCCAAGCCTGATGAGAACCTGAAATCCGCTAGCAAAGAAGAACTCAAGAAAGACGTTAAGAA
TGATGTGAACTGCAAGAGAGGCCATGCAGGGACCACAGATAATGAAAAGAGATCAGAGAGCCAGGGGACAGCCCCAGCCTTCAAGCAGAAGCTGCAAGAT
GTTCATGTGGCAGAGGGCAAGAAGCTGCTGCTCCAGTGCCAGGTGTCTTCTGACCCCCCAGCCACCATCATCTGGACGCTGAACGGAAAGACCCTCAAGA
CCACCAAGTTCATCATCCTCTCCCAGGAAGGCTCACTCTGCTCCGTCTCCATCGAGAAGGCACTGCCTGAGGACAGAGGCTTATACAAGTGTGTAGCCAA
GAATGACGCTGGCCAGGCGGAGTGCTCCTGCCAAGTCACCGTGGATGATGCTCCAGCCAGTGAGAACACCAAGGCCCCAGAGATGAAATCCCGGAGGCCC
AAGAGCTCTCTTCCTCCCGTGCTAGGAACTGAGAGTGATGCGACTGTGAAAAAGAAACCTGCCCCCAAGACACCTCCGAAGGCAGCAATGCCCCCTCAGA
TCATCCAGTTCCCTGAGGACCAGAAGGTACGCGCAGGAGAGTCAGTGGAGCTGTTTGGCAAAGTGACAGGCACTCAGCCCATCACCTGTACCTGGATGAA
GTTCCGAAAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGAGAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGC
TGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCAGGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTG
CCTCTGACATTCGGAGCTCCTCACTGACCCTGTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTC
AGCCAACAAGACGTGGAAGGAACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCA
ATCAACGTGTATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATG
ATGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGATTAGGATCCTG
TTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGCGTGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTACATCCACAAGCAGG
GCATCGTGCACCTGGACCTCAAGCCGGAGAACATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGGCCAGGAGGCTGGA
GAATGCGGGGTCTCTGAAGGTCCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCACAGACATGTGGAGC
ATCGGGGTCATCTGCTACATCCTAGTCAGTGGCCTTTCCCCCTTCATGGGAGACAACGATAACGAAACCTTGGCCAACGTTACCTCAGCCACCTGGGACT
TCGACGACGAGGCATTCGATGAGATCTCCGACGATGCCAAGGATTTCATCAGCAATCTGCTGAAGAAAGATATGAAAAACCGCCTGGACTGCACGCAGTG
CCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCAAGAAACTCTCCAAGGACCGGATGAAGAAGTACATGGCAAGAAGGAAATGGCAG
AAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTATGGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGGTCACCAACCAGCC
CGCTCAATGCAGAAAAACTAGAATCTGAAGAAGATGTGTCCCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAA
GACCATTCGCGATTTAGAAGTTGTGGAGGGAAGTGCTGCTAGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGAC
CAGTCAATCAGGGAGTCCCGCCACTTCCAGATAGACTACGATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGT
ACACCTGCAAGGCTGTCAACAGTCTTGGAGAAGCCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAGAGGAAGA
AGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAACTCAAGATAGTAAAAGC
ACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGCGTTATTGATGGGCATTAATCTATGTT
AGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCAGTAACTTGACTGACCAATTGATTTTAGAGAGAAAGTAACCAAACCAA
ATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAAAAATAAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCCAGAGGGTTC
CTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGAGAACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACT
TTATTCCAAAGTACACTGCAGATGTTCAAACTCTCCATTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATT
AAGGACATTATGCTTCTTCGATTCTGAAGACAGGTCCCTGCTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATC
TAAACTTATCCCCTCTTTGCAGATGTCTAGCAGCTTCAGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAA
CCAGGATTCTTATTTGTGCTGTTATAGAATATCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAAAAGTTAG
TCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAAGATAGCCAGAGTTTAA
TACATCTTCATTCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTGCATCAATCATGCCTTGCCCCCAACCT
TTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGGAATTTTTAACTTTCTTTCACTACATTGGCACTTAAATTTTTTCTTTATAA
AGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATACATTTCCTCTGTGTGTGTGTGTAACATTCCAAATACTTTTTTTTTCTTTT
CCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACTTTTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTA
TCAACATTAGAATTTTGATATTAGTCTTATGTTATCTTCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCT
TTTAAAATAGTTACAATATTTTTCATGATAGCCACAGTATTGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTC
TATCACTTTTGTGTTCAGAATATAACCTTTGTGTGCGTGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAAT
TGTGTTAATGTTCTCTTGGTTTATTATGCCATCAGAATGGTAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTTAAATAAAGGATACCACAGTG
CATGCTGTTTGTTCAA
  • refseq_MYLK.F2 (forward primer)
  • refseq_MYLK.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

GAERARSPRCAPAAGAPRRAPVPRLPGRLRRAG
RILQN*QKPIRAS*REKIKVAPGCLCCSSEQLQE
LPSRELQDAFPVPLAQLPQQTTEKTVTMGDVKL
VASSHISKTSLSVDPSRVDSMPLTEAPAFILPP
RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI
TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC
EATNGSGARQVTVELTVEGSFAKQLGQPVVSKT
LGDRFSAPAVETRPSIWGECPPKFATKLGRVVVK
EGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR
VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS
GKASMSAELSIQGLDSANRSFVRETKATNSDVRK
EVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP
PWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ
KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR
PAPPRPATFPTRQPGLGSQDVVSKAANRRIPME
GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSG
IPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC
LLKARTRDSGTYSCTASNAQGQLSCSWTLQVER
LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG
TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA
LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS
RKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ
VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ
RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT
QAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL
ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN
EDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ
VSLMLQNSSARALPRGREPASCEDLCGGGVGAD
GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVL
KRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVS
TKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVS
EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP
PKPATPDFRSVLGGKKKLPAENGSSSAETLNAK
AVESSKPLSNAQPSGPLKPVGNAKPAETLKPMG
NAKPAETLKPMGNAKPDENLKSASKEELKKDVKN
DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQD
VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK
TTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAK
NDAGQAECSCQVTVDDAPASENTKAPEMKSRRP
KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQ
IIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK
FRKQIQESEHMKVENSENGSKLTILAARQEHCG
CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC
ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDS
ANKTWKELATCRSTSFNVQDLLPDHEYKFRVRA
INVYGTSEPSQESELTTVGEKPEEPKDEVEVSD
DDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSC
LSASLTRTLS*RSVSASSTCGRSRREWSTSTSR
ASCTWTSSRRTSCVSTRRAPGSSSSTLVWPGGW
RMRGL*RSSLAPQNLWLLK*STMSPSATPQTCGA
SGSSATS*SVAFPPSWETTITKPWPTLPQPPGT
STTRHSMRSPTMPRISSAIC*RKI*KTAWTARS
AFSIHG**KIPRTWRPRNSPRTG*RSTWQEGNGR
KRAML*EPLEDCPLWQ*SQGSVAGNPQQGHQPA
RSMQKN*NLKKMCPKLSLRLLLRKSLM*NPISL
RPFAI*KLWREVLLDLTARLKDTQTPRLSGSKMT
SQSGSPATSR*TTMRTGTAL*LLVMFAGMTMPS
TPARLSTVLEKPPAQQSSLWKRWRKVKGKGKRK
KSETKPEKSSF*VILKGLFL*NSKKKKKLKIVKA
PSVIDYRLGHLWVDSSETAVDT*QRY*WALIYV
SWHLKILVQLDFI*GNHQ*LD*PIDFREKVTKP
NIYLGKVINSPLECAHEK*GQNKSSGPQLSPEGS
WGWEASLSPPPDSRELGFLPVLQQFISESS*AT
LFQSTLQMFKLSISLSPSTCQFC*LSTCHECKH
*GHYASSILKTGPCSWMTLASLGKYFSSKISRKS
KLIPSLQMSSSFRHLVKNPWEKKNPC*CGFLCK
PGFLFVLL*NISSERVVKIFVFEYRRNQFAEKL
VLIIYWPR*NRFQLIKSWRTPCTLESPPR*PEFN
TSSFSTLSKELDLPYGFHIFLLKCASIMPCPQP
LNIFLDLVNALRLASLGIFNFLSLHWHLNFFFI
KLFEGHKQRP*LMIDLIHFLCVCV*HSKYFFFLF
HCL*GATI*YF*GTF*EFLKNQFKITSVQSYTV
STLEF*Y*SYVIFHSIFICFLLLVSNCQYFSFC
F*NSYNIFHDSHSIATVYYNKGFLFDLAHSKLFS
ITFVFRI*PLCACMLCVCMCGVYVCYRLMPSWN
CVNVLLVYYAIRMVNENTTTVVSSQFLNKGYHS
ACCLF

Frame 1

ALSELGARAVRLRPGRPAERRCPGSRAAFAARE
GFFKINRNQFGPAEEKK*RWLPAASAAVQSNFR
SFPAESFRTPFLSHWPSCHNKQQRRR*PWGM*SW
LPRHTFPKPPSVWIPQELTPCP*QRPLLSFCPL
GTSASKKEPPPSSKGGSGVTQSPR*HGTETGNP
SPAGAASCWIAASGGLSAL*FMLSMRRTGESIPV
KPPMAVVLAR*QWS*Q*KEVLRSSLVSLLFPKP
*GIDFQLQQWRPVLASGGSAHQSLLPSWAELWS
KKDRWDDSPARSLAGPNRRSPGSREMFHCSRVPV
CLCLRRTACRFWKSMESTKMTWECTRAWW*TGR
GRPRCQLNFPSKVWTVPIGHL*EKQKPPIQMSG
KR*PM*SQRSRSWTVWRLQPKARTAPAPREVAPH
PGLQTASLSPQGSPSWSHARTRPERPRRPRSFR
RLPAPSPCRPQEFSRNQEHQAWGSYHLLEKRGR
GQLLPVQPPSPPGSLAWGAKML*ARLLTGESPWR
ARGIQHSPNLRASPKARRSRKIKLSSSDVKFPG
FQSLKWPGSWKAPP*GDRKAALRFMKMLAPITS
AC*KPGPGTVGHTAALLPTPKASCPVAGPSKWKG
LP*WRWPPPSPVS*RTALLLRARILCCSAPYGG
PQCPGSLGC*MGSPSSTLAPPARPAWLSSTSRM
PCRRTMAPTPA*LRMPWGRCPAAPGSPSMKRRVA
GRVSTFCLWLPASPLHPSSCRASLISKSWMEAR
SL*LSKCQGIHPLKSSGCTMGMRSKSQRTSTLN
REELSTAFVSRKCSRRTRARTPARPGTALERSAP
RPCSRYKSLTMAPSPGSSVSLAQ*QPPWARVSS
SPAP*LVTPFLPCTGSEMAKPSAKTLATSRCFR
MRTCSPWF*RRCSPGMPASMRSCSRTGLANAVAR
CH*CYRTALPEPFHGGGSLPAARTSVVEELVLM
VVVVTAMGP*GLAGQQEGRVG*RRKTARTCEGC
*RGAWRRGSTLRRRSASRRWSSWTSETSWGRR*V
QRPYRKTT*RRSQPSRWISVPTCSGK*SQRLCL
RKRGRCTAPSRSIFALSWPRRGLPRPPCLRRCH
RQNLPPRIFAQCWVARRNYQQRMAAAVPRP*MPR
QWRVPSP*AMHSLQGP*NPWATPSLLRP*SQWA
TPSLPRP*SPWAMPSLMRT*NPLAKKNSRKTLR
MM*TAREAMQGPQIMKRDQRARGQPQPSSRSCKM
FMWQRARSCCSSARCLLTPQPPSSGR*TERPSR
PPSSSSSPRKAHSAPSPSRRHCLRTEAYTSV*P
RMTLARRSAPAKSPWMMLQPVRTPRPQR*NPGGP
RALFLPC*ELRVMRL*KRNLPPRHLRRQQCPLR
SSSSLRTRRYAQESQWSCLAK*QALSPSPVPG*
SSESRSRKAST*RWRTARMAASSPSWPRARSTAA
ATHCWWRTSWAAGRPRSTSLSWISQTPQLAHLV
PLTFGAPH*PCPGMAPHMMGAVLYSPTASRSGT
QPTRRGRN*PHAAAPLSTSRTCCLTTNISSVYVQ
STCMEPVSQARSLNSQR*ERNLKSRRMKWRCQM
MMRRSPRLITGQ*QSILNKKYLTSTTLRRD*DP
V*AHH*RGL*ADGA*VHQVHAADLGGSGVHPQAG
HRAPGPQAGEHHVCQQDGHQDQAHRLWSGQEAG
ECGVSEGPLWHPRICGS*SDQL*AHRLRHRHVE
HRGHLLHPSQWPFPLHGRQR*RNLGQRYLSHLGL
RRRGIR*DLRRCQGFHQQSAEERYEKPPGLHAV
PSASMANERYQEHGGQETLQGPDEEVHGKKEMA
ENGQCCESHWKTVLYGNDLRAQWQEILNRVTNQP
AQCRKTRI*RRCVPSFP*GCC*GKASCKTLFL*
DHSRFRSCGGKCC*I*LQD*RIPRPRGCLVQR*
PVNQGVPPLPDRLR*GRELLFNY**CLRG*RCQV
HLQGCQQSWRSHLHSRAHCGNDGGR*RGRGRGR
RVKQSQRKAVSKSY*KDYFSKTQKKKKNSR**K
HLV**IIG*VICGLILQKQQLIPSSVIDGH*SML
VGTLRY*CS*ISFREITSNLTDQLILERK*PNQ
IFIWAKS*ILHLNALMKNKAKTRVLGHSSAQRV
PGDGRPLSPHPLTLENWVFSQYSSNSFLKAVEPL
YSKVHCRCSNSPFLFPLPPASFADSQLVMSVSI
KDIMLLRF*RQVPAHG*LWLP*ENIFLPKSVGN
LNLSPLCRCLAASDIWLRTHGKKKILANVVSFVN
QDSYLCCYRISALNVW*RFLCLNIGEISLLKS*
S*LSIGHDETDFN**RAGELHVLWNLLQDSQSL
IHLHSQHSPKNLTYLMGSIFFFLNVHQSCLAPNL
*IYS*TW*MHSDLRL*EFLTFFHYIGT*IFSL*
SFLKVINKDHN***T*YISSVCVCNIPNTFFFF
STVCKVQQFNIFKGLFKSSLRTNLKLLQCNPTQY
QH*NFDISLMLSSILFLSAFCC*FQTASIFPFA
FKIVTIFFMIATVLPQFIIIKGFYLI*RIQSFF
LSLLCSEYNLCVRVCCVCACVAYMCVTG*CLLGI
VLMFSWFIMPSEW*MRTLQL*SAHNF*IKDTTV
HAVCS

Frame 2

R*ASSEPALCACGRGAPPSAGAPAPGPPSPRGK
DSSKLTETNSGQLKRKNKGGSRLPLLQFRATSG
ASQPRASGRLSCPTGPVATTNNREDGDHGGCEA
GCLVTHFQNLPQCGSLKS*LHAPDRGPCFHFAPS
EPLHQRRSHRQVRRAGPGLPRAPGDMAQKRATH
HQRGPLPAGLRHPGDFQPCDSCCP*GGQGKVYL
*SHQWQWCSPGDSGVDSRRKFCEAAWSACCFQNL
RG*IFSSSSGDPS*HLGGVPTKVCYQAGPSCGQ
RRTDGTILLQDHWPAPTAGHLAQGKCSTAAECP
CVCV*EERHAGSGNPWSQPR*RGSVHVPGGERVG
EGLDVS*TFHPRFGQCQ*VICERNKSHQFRCQE
RGDQCNLKGVEAGQSGGCSQKQELLQPPERWLP
TLGCKQPASAPKGVQAGVMQGLAQNGPADPGPSE
DFQLHHPAGRKSSAGTKSTRPGGPITFWRREEE
ASSSPSSHLPHQAAWPGEPRCCEQGC*QENPHG
GPEGFSIPQI*EQAPKPGGQGKSNCQVQM*SFRD
SKA*SGLVPGRHPREETGRQH*GL*RCWLPLPL
PAESPDQGQWDIQLHCFQRPRPAVL*LDPPSGK
ACRDGGGPLLLQCPEGLRCY*GPGFCAAVLRTGD
PSAPDHLAAEWAAHPVRSLHLRGRRG*APHPGC
PAGGPWHLHLPS*ECLGAGVLQRLGHRP*KEE*
QEE*VPSACGSQQAHCTHLPAGPL*SQSHGWKPG
HYDCPSVRESTP*SHLAAQWE*DPRVRGLPL*T
ERNSAQPLYPGSVPGGHGHVHLRGLEQRWRGPH
PGRAHGTRASRWHPALVHQ*ASLSDSLPGPECPH
LLRHSW*PLSYRALAQRWQSPLQRHWPLRGASE
*GRVHPGSKEGAALACRPV*DPAQEPGWRMQLP
GVTDATEQLCQSPSTGEGACQLRGPLWWRSWC*W
WW**PLWVPEAWLASKRAGLARGGRRRGRARGA
EEARGDEAAH*GGDPPAGGGAAGLPRPPGEEGE
YKDPIGRRPEGDPSRADGFPCQPAAASEAKDCV*
GREEGAQPPAGRFSLCPGQEGDFQDPRA*EGAT
AKTCHPGFSLSAGWQEEITSREWQQQCRDPECQ
GSGEFQAPEQCTAFRALETRGQRQAC*DPEANGQ
RQACRDPEAHGQCQA**EPEIR*QRRTQERR*E
*CELQERPCRDHR**KEIREPGDSPSLQAEAAR
CSCGRGQEAAAPVPGVF*PPSHHHLDAERKDPQD
HQVHHPLPGRLTLLRLHREGTA*GQRLIQVCSQ
E*RWPGGVLLPSHRG*CSSQ*EHQGPRDEIPEA
QELSSSRARN*E*CDCEKETCPQDTSEGSNAPSD
HPVP*GPEGTRRRVSGAVWQSDRHSAHHLYLDE
VPKADPGKRAHEGGEQREWQQAHHPGRAPGALR
LLHTAGGEQAGQQAGPGQPHCRG*ARPPSWHTLC
L*HSELLTDPVLVWLLI*WGQCCTVLQHRDLGL
SQQDVEGTSHMPQHLFQRPGPAA*PRI*VPCTC
NQRVWNQ*AKPGV*THNGRRET*RAEG*SGGVR*
**EGARG*LPDSDNQY*TKSI*LLRH*GEIRIL
FERIIDEDFELTERECIKYMRQISEGVEYIHKQ
GIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLE
NAGSLKVLFGTPEFVAPEVINYEPIGYATDMWS
IGVICYILVSGLSPFMGDNDNETLANVTSATWD
FDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQC
LQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQ
KTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTS
PLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK
TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD
QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK
YTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE
E*NKAREKQFLSHIKRTISLKLKKKKKTQDSKS
T*CDRLSVRSFVG*FFRNSS*YLAALLMGINLC
*LAP*DTSAARFHLGKSPVT*LTN*F*RESNQTK
YLSGQSHKFST*MRS*KIRPKQEFWATAQPRGF
LGMGGLSLPTP*L*RTGFSPSTPAIHF*KQLSH
FIPKYTADVQTLHFSFPFHLPVLLTLNLS*V*AL
RTLCFFDSEDRSLLMDDSGFLRKIFFFQNQ*EI
*TYPLFADV*QLQTFG*EPMGKKKSLLMWFPL*
TRILICAVIEYQL*TCGKDFCV*I*EKSVC*KVS
LNYLLATMKQISTDKELENSMYFGISSKIARV*
YIFILNTLQRT*PTLWVPYFSS*MCINHALPPT
FKYILRPGKCTQTCVFRNF*LSFTTLALKFFLYK
AF*RS*TKTIIDDRPNTFPLCVCVTFQILFFSF
PLFVRCNNLIFLRDFLRVP*EPI*NYFSAILHS
INIRILILVLCYLPFYFYLLFAASFKLPVFFLLL
LK*LQYFS**PQYCHSLL**RVFI*FSAFKAFF
YHFCVQNITFVCVYVVCVHVWRICVLQVNAFLE
LC*CSLGLLCHQNGK*EHYNCSQLTIFK*RIPQC
MLFVQ

Sequence NM_053030

CTCAGGGATTTGCTCTCCCCTGAAGTTTCTTTCTTACCCAGCCCCTTTTCCTCCTGCTACTTTCCTTTTTCCCTACACTGGTTGCAGGGGGAGGGAGCCT
GCCAGCTGCGAGGACCTCTGTGGTGGAGGAGTTGGTGCTGATGGTGGTGGTAGTGACCGCTATGGGTCCCTGAGGCCTGGCTGGCCAGCAAGAGGGCAGG
GTTGGCTAGAGGAGGAAGACGGCGAGGACGTGCGAGGGGTGCTGAAGAGGCGCGTGGAGACGAGGCAGCACACTGAGGAGGCGATCCGCCAGCAGGAGGT
GGAGCAGCTGGACTTCCGAGACCTCCTGGGGAAGAAGGTGAGTACAAAGACCCTATCGGAAGACGACCTGAAGGAGATCCCAGCCGAGCAGATGGATTTC
CGTGCCAACCTGCAGCGGCAAGTGAAGCCAAAGACTGTGTCTGAGGAAGAGAGGAAGGTGCACAGCCCCCAGCAGGTCGATTTTCGCTCTGTCCTGGCCA
AGAAGGGGACTTCCAAGACCCCCGTGCCTGAGAAGGTGCCACCGCCAAAACCTGCCACCCCGGATTTTCGCTCAGTGCTGGGTGGCAAGAAGAAATTACC
AGCAGAGAATGGCAGCAGCAGTGCCGAGACCCTGAATGCCAAGGCAGTGGAGAGTTCCAAGCCCCTGAGCAATGCACAGCCTTCAGGGCCCTTGAAACCC
GTGGGCAACGCCAAGCCTGCTGAGACCCTGAAGCCAATGGGCAACGCCAAGCCTGCCGAGACCCTGAAGCCCATGGGCAATGCCAAGCCTGATGAGAACC
TGAAATCCGCTAGCAAAGAAGAACTCAAGAAAGACGTTAAGAATGATGTGAACTGCAAGAGAGGCCATGCAGGGACCACAGATAATGAAAAGAGATCAGA
GAGCCAGGGGACAGCCCCAGCCTTCAAGCAGAAGCTGCAAGATGTTCATGTGGCAGAGGGCAAGAAGCTGCTGCTCCAGTGCCAGGTGTCTTCTGACCCC
CCAGCCACCATCATCTGGACGCTGAACGGAAAGACCCTCAAGACCACCAAGTTCATCATCCTCTCCCAGGAAGGCTCACTCTGCTCCGTCTCCATCGAGA
AGGCACTGCCTGAGGACAGAGGCTTATACAAGTGTGTAGCCAAGAATGACGCTGGCCAGGCGGAGTGCTCCTGCCAAGTCACCGTGGATGATGCTCCAGC
CAGTGAGAACACCAAGGCCCCAGAGATGAAATCCCGGAGGCCCAAGAGCTCTCTTCCTCCCGTGCTAGGAACTGAGAGTGATGCGACTGTGAAAAAGAAA
CCTGCCCCCAAGACACCTCCGAAGGCAGCAATGCCCCCTCAGATCATCCAGTTCCCTGAGGACCAGAAGGTACGCGCAGGAGAGTCAGTGGAGCTGTTTG
GCAAAGTGACAGGCACTCAGCCCATCACCTGTACCTGGATGAAGTTCCGAAAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGAGAATGG
CAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCAGGCCCAGGTCAACCTC
ACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGACATTCGGAGCTCCTCACTGACCCTGTCCTGGTATGGCTCCTCATATGATG
GGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAACAAGACGTGGAAGGAACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCA
GGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACGTGTATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGA
GAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATGATGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAA
AAGTATCTGACTTCTACGACATTGAGGAGAGATTAGGATCTGGGAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGG
GAAGTTCTTCAAGGCATATTCAGCAAAAGAGAAAGAGAATATCCGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTG
GATGCCTTTGAAGAAAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTCAGGAGGGGAG
CTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGG
AGCGTGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGAACATCAT
GTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGGTCCTCTTTGGCACCCCA
GAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCACAGACATGTGGAGCATCGGGGTCATCTGCTACATCCTAGTCAGTGGCCTTT
CCCCCTTCATGGGAGACAACGATAACGAAACCTTGGCCAACGTTACCTCAGCCACCTGGGACTTCGACGACGAGGCATTCGATGAGATCTCCGACGATGC
CAAGGATTTCATCAGCAATCTGCTGAAGAAAGATATGAAAAACCGCCTGGACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAAC
ATGGAGGCCAAGAAACTCTCCAAGGACCGGATGAAGAAGTACATGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGT
CCTCTATGGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAGATGT
GTCCCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGTGGAGGGAAGTGCT
GCTAGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGGAGTCCCGCCACTTCCAGATAGACT
ACGATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACACCTGCAAGGCTGTCAACAGTCTTGGAGAAGCCAC
CTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAGAGGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGT
CATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAACTCAAGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGG
GTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGCGTTATTGATGGGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCA
TTTAGGGAAATCACCAGTAACTTGACTGACCAATTGATTTTAGAGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGA
ATGCGCTCATGAAAAATAAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGAC
TCTAGAGAACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTCTCCA
TTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTCTGAAGACAGGTCC
CTGCTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCCTCTTTGCAGATGTCTAGCAGCTTC
AGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCAGGATTCTTATTTGTGCTGTTATAGAATATCAGCT
CTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAAAAGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCA
ACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAAGATAGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACTTGAC
CTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTGCATCAATCATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGAC
TTGCGTCTTTAGGAATTTTTAACTTTCTTTCACTACATTGGCACTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGAT
GATAGACCTAATACATTTCCTCTGTGTGTGTGTGTAACATTCCAAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAA
GGGACTTTTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTTATCT
TCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTCATGATAGCCACAG
TATTGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTGTTCAGAATATAACCTTTGTGTGCG
TGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGTGTTAATGTTCTCTTGGTTTATTATGCCATCAGAA
TGGTAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTTAAATAAAGGATACCACAGTGCATGCTGTTTGTTCAA
  • refseq_MYLK.F2 (forward primer)
  • refseq_MYLK.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

LRDLLSPEVSFLPSPFSSCYFPFSLHWLQGEGA
CQLRGPLWWRSWC*WWW**PLWVPEAWLASKRAG
LARGGRRRGRARGAEEARGDEAAH*GGDPPAGG
GAAGLPRPPGEEGEYKDPIGRRPEGDPSRADGF
PCQPAAASEAKDCV*GREEGAQPPAGRFSLCPGQ
EGDFQDPRA*EGATAKTCHPGFSLSAGWQEEIT
SREWQQQCRDPECQGSGEFQAPEQCTAFRALET
RGQRQAC*DPEANGQRQACRDPEAHGQCQA**EP
EIR*QRRTQERR*E*CELQERPCRDHR**KEIR
EPGDSPSLQAEAARCSCGRGQEAAAPVPGVF*P
PSHHHLDAERKDPQDHQVHHPLPGRLTLLRLHRE
GTA*GQRLIQVCSQE*RWPGGVLLPSHRG*CSS
Q*EHQGPRDEIPEAQELSSSRARN*E*CDCEKE
TCPQDTSEGSNAPSDHPVP*GPEGTRRRVSGAVW
QSDRHSAHHLYLDEVPKADPGKRAHEGGEQREW
QQAHHPGRAPGALRLLHTAGGEQAGQQAGPGQP
HCRG*ARPPSWHTLCL*HSELLTDPVLVWLLI*W
GQCCTVLQHRDLGLSQQDVEGTSHMPQHLFQRP
GPAA*PRI*VPCTCNQRVWNQ*AKPGV*THNGR
RET*RAEG*SGGVR***EGARG*LPDSDNQY*TK
SI*LLRH*GEIRIWEIWTGLSTCRKENSKSLGR
EVLQGIFSKREREYPAGD*HHELPPPP*AGPVC
GCL*RKGQHRHGPGDRVRRG
AV*AHH*RGL*ADG
A*VHQVHAADLGGSGVHPQAGHRAPGPQAGEHH
VCQQDGHQDQAHRLWSGQEAGECGVSEGPLWHP
RICGS*SDQL*AHRLRHRHVEHRGHLLHPSQWPF
PLHGRQR*RNLGQRYLSHLGLRRRGIR*DLRRC
QGFHQQSAEERYEKPPGLHAVPSASMANERYQE
HGGQETLQGPDEEVHGKKEMAENGQCCESHWKTV
LYGNDLRAQWQEILNRVTNQPAQCRKTRI*RRC
VPSFP*GCC*GKASCKTLFL*DHSRFRSCGGKC
C*I*LQD*RIPRPRGCLVQR*PVNQGVPPLPDRL
R*GRELLFNY**CLRG*RCQVHLQGCQQSWRSH
LHSRAHCGNDGGR*RGRGRGRRVKQSQRKAVSK
SY*KDYFSKTQKKKKNSR**KHLV**IIG*VICG
LILQKQQLIPSSVIDGH*SMLVGTLRY*CS*IS
FREITSNLTDQLILERK*PNQIFIWAKS*ILHL
NALMKNKAKTRVLGHSSAQRVPGDGRPLSPHPLT
LENWVFSQYSSNSFLKAVEPLYSKVHCRCSNSP
FLFPLPPASFADSQLVMSVSIKDIMLLRF*RQV
PAHG*LWLP*ENIFLPKSVGNLNLSPLCRCLAAS
DIWLRTHGKKKILANVVSFVNQDSYLCCYRISA
LNVW*RFLCLNIGEISLLKS*S*LSIGHDETDF
N**RAGELHVLWNLLQDSQSLIHLHSQHSPKNLT
YLMGSIFFFLNVHQSCLAPNL*IYS*TW*MHSD
LRL*EFLTFFHYIGT*IFSL*SFLKVINKDHN*
**T*YISSVCVCNIPNTFFFFSTVCKVQQFNIFK
GLFKSSLRTNLKLLQCNPTQYQH*NFDISLMLS
SILFLSAFCC*FQTASIFPFAFKIVTIFFMIAT
VLPQFIIIKGFYLI*RIQSFFLSLLCSEYNLCVR
VCCVCACVAYMCVTG*CLLGIVLMFSWFIMPSE
W*MRTLQL*SAHNF*IKDTTVHAVCS

Frame 1

SGICSPLKFLSYPAPFPPATFLFPYTGCRGREP
ASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQ
GWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEV
EQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDF
RANLQRQVKPKTVSEEERKVHSPQQVDFRSVLA
KKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLP
AENGSSSAETLNAKAVESSKPLSNAQPSGPLKP
VGNAKPAETLKPMGNAKPAETLKPMGNAKPDEN
LKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSE
SQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDP
PATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE
KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA
SENTKAPEMKSRRPKSSLPPVLGTESDATVKKK
PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELF
GKVTGTQPITCTWMKFRKQIQESEHMKVENSENG
SKLTILAARQEHCGCYTLLVENKLGSRQAQVNL
TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYD
GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQ
DLLPDHEYKFRVRAINVYGTSEPSQESELTTVG
EKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQ
KVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAG
KFFKAYSAKEKENIRQEISIMNCLHHPKLVQCV
DAFEEKANIVMVLEIVSGGE
LFERIIDEDFELT
ERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM
CVNKTGTRIKLIDFGLARRLENAGSLKVLFGTP
EFVAPEVINYEPIGYATDMWSIGVICYILVSGL
SPFMGDNDNETLANVTSATWDFDDEAFDEISDDA
KDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKN
MEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRL
SSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDV
SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSA
ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID
YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEAT
CTAELIVETMEEGEGEGEEEEE*NKAREKQFLS
HIKRTISLKLKKKKKTQDSKST*CDRLSVRSFV
G*FFRNSS*YLAALLMGINLC*LAP*DTSAARFH
LGKSPVT*LTN*F*RESNQTKYLSGQSHKFST*
MRS*KIRPKQEFWATAQPRGFLGMGGLSLPTP*
L*RTGFSPSTPAIHF*KQLSHFIPKYTADVQTLH
FSFPFHLPVLLTLNLS*V*ALRTLCFFDSEDRS
LLMDDSGFLRKIFFFQNQ*EI*TYPLFADV*QL
QTFG*EPMGKKKSLLMWFPL*TRILICAVIEYQL
*TCGKDFCV*I*EKSVC*KVSLNYLLATMKQIS
TDKELENSMYFGISSKIARV*YIFILNTLQRT*
PTLWVPYFSS*MCINHALPPTFKYILRPGKCTQT
CVFRNF*LSFTTLALKFFLYKAF*RS*TKTIID
DRPNTFPLCVCVTFQILFFSFPLFVRCNNLIFL
RDFLRVP*EPI*NYFSAILHSINIRILILVLCYL
PFYFYLLFAASFKLPVFFLLLLK*LQYFS**PQ
YCHSLL**RVFI*FSAFKAFFYHFCVQNITFVC
VYVVCVHVWRICVLQVNAFLELC*CSLGLLCHQN
GK*EHYNCSQLTIFK*RIPQCMLFVQ

Frame 2

QGFALP*SFFLTQPLFLLLLSFFPTLVAGGGSL
PAARTSVVEELVLMVVVVTAMGP*GLAGQQEGR
VG*RRKTARTCEGC*RGAWRRGSTLRRRSASRR
WSSWTSETSWGRR*VQRPYRKTT*RRSQPSRWIS
VPTCSGK*SQRLCLRKRGRCTAPSRSIFALSWP
RRGLPRPPCLRRCHRQNLPPRIFAQCWVARRNY
QQRMAAAVPRP*MPRQWRVPSP*AMHSLQGP*NP
WATPSLLRP*SQWATPSLPRP*SPWAMPSLMRT
*NPLAKKNSRKTLRMM*TAREAMQGPQIMKRDQ
RARGQPQPSSRSCKMFMWQRARSCCSSARCLLTP
QPPSSGR*TERPSRPPSSSSSPRKAHSAPSPSR
RHCLRTEAYTSV*PRMTLARRSAPAKSPWMMLQ
PVRTPRPQR*NPGGPRALFLPC*ELRVMRL*KRN
LPPRHLRRQQCPLRSSSSLRTRRYAQESQWSCL
AK*QALSPSPVPG*SSESRSRKAST*RWRTARM
AASSPSWPRARSTAAATHCWWRTSWAAGRPRSTS
LSWISQTPQLAHLVPLTFGAPH*PCPGMAPHMM
GAVLYSPTASRSGTQPTRRGRN*PHAAAPLSTS
RTCCLTTNISSVYVQSTCMEPVSQARSLNSQR*E
RNLKSRRMKWRCQMMMRRSPRLITGQ*QSILNK
KYLTSTTLRRD*DLGNLDRSFDL*KRKLEKSGQ
GSSSRHIQQKRKRISGRRLAS*TASTTLSWSSVW
MPLKKRPTSSWSWRSCQEGS
CLSASLTRTLS*R
SVSASSTCGRSRREWSTSTSRASCTWTSSRRTS
CVSTRRAPGSSSSTLVWPGGWRMRGL*RSSLAPQ
NLWLLK*STMSPSATPQTCGASGSSATS*SVAF
PPSWETTITKPWPTLPQPPGTSTTRHSMRSPTM
PRISSAIC*RKI*KTAWTARSAFSIHG**KIPRT
WRPRNSPRTG*RSTWQEGNGRKRAML*EPLEDC
PLWQ*SQGSVAGNPQQGHQPARSMQKN*NLKKM
CPKLSLRLLLRKSLM*NPISLRPFAI*KLWREVL
LDLTARLKDTQTPRLSGSKMTSQSGSPATSR*T
TMRTGTAL*LLVMFAGMTMPSTPARLSTVLEKP
PAQQSSLWKRWRKVKGKGKRKKSETKPEKSSF*V
ILKGLFL*NSKKKKKLKIVKAPSVIDYRLGHLW
VDSSETAVDT*QRY*WALIYVSWHLKILVQLDF
I*GNHQ*LD*PIDFREKVTKPNIYLGKVINSPLE
CAHEK*GQNKSSGPQLSPEGSWGWEASLSPPPD
SRELGFLPVLQQFISESS*ATLFQSTLQMFKLS
ISLSPSTCQFC*LSTCHECKH*GHYASSILKTGP
CSWMTLASLGKYFSSKISRKSKLIPSLQMSSSF
RHLVKNPWEKKNPC*CGFLCKPGFLFVLL*NIS
SERVVKIFVFEYRRNQFAEKLVLIIYWPR*NRFQ
LIKSWRTPCTLESPPR*PEFNTSSFSTLSKELD
LPYGFHIFLLKCASIMPCPQPLNIFLDLVNALR
LASLGIFNFLSLHWHLNFFFIKLFEGHKQRP*LM
IDLIHFLCVCV*HSKYFFFLFHCL*GATI*YF*
GTF*EFLKNQFKITSVQSYTVSTLEF*Y*SYVI
FHSIFICFLLLVSNCQYFSFCF*NSYNIFHDSHS
IATVYYNKGFLFDLAHSKLFSITFVFRI*PLCA
CMLCVCMCGVYVCYRLMPSWNCVNVLLVYYAIR
MVNENTTTVVSSQFLNKGYHSACCLF

Sequence NM_053028

GGCGCTGAGCGAGCTCGGAGCCCGCGCTGTGCGCCTGCGGCCGGGGCGCCCCGCCGAGCGCCGGTGCCCCGGCTCCCGGGCCGCCTTCGCCGCGCGGGAA
GGATTCTTCAAAATTAACAGAAACCAATTCGGGCCAGCTGAAGAGAAAAAATAAAGGTGGCTCCCGGCTGCCTCTGCTGCAGTTCAGAGCAACTTCAGGA
GCTTCCCAGCCGAGAGCTTCAGGACGCCTTTCCTGTCCCACTGGCCCAGTTGCCACAACAAACAACAGAGAAGACGGTGACCATGGGGGATGTGAAGCTG
GTTGCCTCGTCACACATTTCCAAAACCTCCCTCAGTGTGGATCCCTCAAGAGTTGACTCCATGCCCCTGACAGAGGCCCCTGCTTTCATTTTGCCCCCTC
GGAACCTCTGCATCAAAGAAGGAGCCACCGCCAAGTTCGAAGGGCGGGTCCGGGGTTACCCAGAGCCCCAGGTGACATGGCACAGAAACGGGCAACCCAT
CACCAGCGGGGGCCGCTTCCTGCTGGATTGCGGCATCCGGGGGACTTTCAGCCTTGTGATTCATGCTGTCCATGAGGAGGACAGGGGAAAGTATACCTGT
GAAGCCACCAATGGCAGTGGTGCTCGCCAGGTGACAGTGGAGTTGACAGTAGAAGGAAGTTTTGCGAAGCAGCTTGGTCAGCCTGTTGTTTCCAAAACCT
TAGGGGATAGATTTTCAGCTCCAGCAGTGGAGACCCGTCCTAGCATCTGGGGGGAGTGCCCACCAAAGTTTGCTACCAAGCTGGGCCGAGTTGTGGTCAA
AGAAGGACAGATGGGACGATTCTCCTGCAAGATCACTGGCCGGCCCCAACCGCAGGTCACCTGGCTCAAGGGAAATGTTCCACTGCAGCCGAGTGCCCGT
GTGTCTGTGTCTGAGAAGAACGGCATGCAGGTTCTGGAAATCCATGGAGTCAACCAAGATGACGTGGGAGTGTACACGTGCCTGGTGGTGAACGGGTCGG
GGAAGGCCTCGATGTCAGCTGAACTTTCCATCCAAGGTTTGGACAGTGCCAATAGGTCATTTGTGAGAGAAACAAAAGCCACCAATTCAGATGTCAGGAA
AGAGGTGACCAATGTAATCTCAAAGGAGTCGAAGCTGGACAGTCTGGAGGCTGCAGCCAAAAGCAAGAACTGCTCCAGCCCCCAGAGAGGTGGCTCCCCA
CCCTGGGCTGCAAACAGCCAGCCTCAGCCCCCAAGGGAGTCCAAGCTGGAGTCATGCAAGGACTCGCCCAGAACGGCCCCGCAGACCCCGGTCCTTCAGA
AGACTTCCAGCTCCATCACCCTGCAGGCCGCAAGAGTTCAGCCGGAACCAAGAGCACCAGGCCTGGGGGTCCTATCACCTTCTGGAGAAGAGAGGAAGAG
GCCAGCTCCTCCCCGTCCAGCCACCTTCCCCACCAGGCAGCCTGGCCTGGGGAGCCAAGATGTTGTGAGCAAGGCTGCTAACAGGAGAATCCCCATGGAG
GGCCAGAGGGATTCAGCATTCCCCAAATTTGAGAGCAAGCCCCAAAGCCAGGAGGTCAAGGAAAATCAAACTGTCAAGTTCAGATGTGAAGGGCTTGCCG
TGATGGAGGTGGCCCCCTCCTTCTCCAGTGTCCTGAAGGACTGCGCTGTTATTGAGGGCCAGGATTTTGTGCTGCAGTGCTCCGTACGGGGGACCCCAGT
GCCCCGGATCACTTGGCTGCTGAATGGGCAGCCCATCCAGTACGCTCGCTCCACCTGCGAGGCCGGCGTGGCTGAGCTCCACATCCAGGATGCCCTGCCG
GAGGACCATGGCACCTACACCTGCCTAGCTGAGAATGCCTTGGGGCAGGTGTCCTGCAGCGCCTGGGTCACCGTCCATGAAAAGAAGAGTAGCAGGAAGA
GTGAGTACCTTCTGCCTGTGGCTCCCAGCAAGCCCACTGCACCCATCTTCCTGCAGGGCCTCTCTGATCTCAAAGTCATGGATGGAAGCCAGGTCACTAT
GACTGTCCAAGTGTCAGGGAATCCACCCCCTGAAGTCATCTGGCTGCACAATGGGAATGAGATCCAAGAGTCAGAGGACTTCCACTTTGAACAGAGAGGA
ACTCAGCACAGCCTTTGTATCCAGGAAGTGTTCCCGGAGGACACGGGCACGTACACCTGCGAGGCCTGGAACAGCGCTGGAGAGGTCCGCACCCAGGCCG
TGCTCACGGTACAAGAGCCTCACGATGGCACCCAGCCCTGGTTCATCAGTAAGCCTCGCTCAGTGACAGCCTCCCTGGGCCAGAGTGTCCTCATCTCCTG
CGCCATAGCTGGTGACCCCTTTCCTACCGTGCACTGGCTCAGAGATGGCAAAGCCCTCTGCAAAGACACTGGCCACTTCGAGGTGCTTCAGAATGAGGAC
GTGTTCACCCTGGTTCTAAAGAAGGTGCAGCCCTGGCATGCCGGCCAGTATGAGATCCTGCTCAAGAACCGGGTTGGCGAATGCAGTTGCCAGGTGTCAC
TGATGCTACAGAACAGCTCTGCCAGAGCCCTTCCACGGGGGAGGGAGCCTGCCAGCTGCGAGGACCTCTGTGGTGGAGGAGTTGGTGCTGATGGTGGTGG
TAGTGACCGCTATGGGTCCCTGAGGCCTGGCTGGCCAGCAAGAGGGCAGGGTTGGCTAGAGGAGGAAGACGGCGAGGACGTGCGAGGGGTGCTGAAGAGG
CGCGTGGAGACGAGGCAGCACACTGAGGAGGCGATCCGCCAGCAGGAGGTGGAGCAGCTGGACTTCCGAGACCTCCTGGGGAAGAAGGTGAGTACAAAGA
CCCTATCGGAAGACGACCTGAAGGAGATCCCAGCCGAGCAGATGGATTTCCGTGCCAACCTGCAGCGGCAAGTGAAGCCAAAGACTGTGTCTGAGGAAGA
GAGGAAGGTGCACAGCCCCCAGCAGGTCGATTTTCGCTCTGTCCTGGCCAAGAAGGGGACTTCCAAGACCCCCGTGCCTGAGAAGGTGCCACCGCCAAAA
CCTGCCACCCCGGATTTTCGCTCAGTGCTGGGTGGCAAGAAGAAATTACCAGCAGAGAATGGCAGCAGCAGTGCCGAGACCCTGAATGCCAAGGCAGTGG
AGAGTTCCAAGCCCCTGAGCAATGCACAGCCTTCAGGGCCCTTGAAACCCGTGGGCAACGCCAAGCCTGCTGAGACCCTGAAGCCAATGGGCAACGCCAA
GCCTGCCGAGACCCTGAAGCCCATGGGCAATGCCAAGCCTGATGAGAACCTGAAATCCGCTAGCAAAGAAGAACTCAAGAAAGACGTTAAGAATGATGTG
AACTGCAAGAGAGGCCATGCAGGGACCACAGATAATGAAAAGAGATCAGAGAGCCAGGGGACAGCCCCAGCCTTCAAGCAGAAGCTGCAAGATGTTCATG
TGGCAGAGGGCAAGAAGCTGCTGCTCCAGTGCCAGGTGTCTTCTGACCCCCCAGCCACCATCATCTGGACGCTGAACGGAAAGACCCTCAAGACCACCAA
GTTCATCATCCTCTCCCAGGAAGGCTCACTCTGCTCCGTCTCCATCGAGAAGGCACTGCCTGAGGACAGAGGCTTATACAAGTGTGTAGCCAAGAATGAC
GCTGGCCAGGCGGAGTGCTCCTGCCAAGTCACCGTGGATGATGCTCCAGCCAGTGAGAACACCAAGGCCCCAGAGATGAAATCCCGGAGGCCCAAGAGCT
CTCTTCCTCCCGTGCTAGGAACTGAGAGTGATGCGACTGTGAAAAAGAAACCTGCCCCCAAGACACCTCCGAAGGCAGCAATGCCCCCTCAGATCATCCA
GTTCCCTGAGGACCAGAAGGTACGCGCAGGAGAGTCAGTGGAGCTGTTTGGCAAAGTGACAGGCACTCAGCCCATCACCTGTACCTGGATGAAGTTCCGA
AAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGAGAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACA
CACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCAGGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGA
CATTCGGAGCTCCTCACTGACCCTGTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAAC
AAGACGTGGAAGGAACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACG
TGTATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATGATGATGA
GAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGATTAGGATCTGGGAAATTT
GGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAGCAAAAGAGAAAGAGAATATCCGGCAGG
AGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAGAAAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTC
AGGAGGGGAG
CTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGCGTGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTAC
ATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGAACATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGG
CCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGGTCCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCAC
AGACATGTGGAGCATCGGGGTCATCTGCTACATCCTAAACCGCCTGGACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATG
GAGGCCAAGAAACTCTCCAAGGACCGGATGAAGAAGTACATGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCT
CTATGGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAGATGTGTC
CCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGTGGAGGGAAGTGCTGCT
AGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGGAGTCCCGCCACTTCCAGATAGACTACG
ATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACACCTGCAAGGCTGTCAACAGTCTTGGAGAAGCCACCTG
CACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAGAGGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCAT
ATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAACTCAAGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGGGTT
GATTCTTCAGAAACAGCAGTTGATACCTAGCAGCGTTATTGATGGGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTT
AGGGAAATCACCAGTAACTTGACTGACCAATTGATTTTAGAGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATG
CGCTCATGAAAAATAAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCT
AGAGAACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTCTCCATTT
CTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTCTGAAGACAGGTCCCTG
CTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCCTCTTTGCAGATGTCTAGCAGCTTCAGA
CATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCAGGATTCTTATTTGTGCTGTTATAGAATATCAGCTCTG
AACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAAAAGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACT
GATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAAGATAGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACTTGACCTA
CCTTATGGGTTCCATATTTTTCTTCTTAAATGTGCATCAATCATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTG
CGTCTTTAGGAATTTTTAACTTTCTTTCACTACATTGGCACTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGAT
AGACCTAATACATTTCCTCTGTGTGTGTGTGTAACATTCCAAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGG
ACTTTTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTTATCTTCC
ATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTCATGATAGCCACAGTAT
TGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTGTTCAGAATATAACCTTTGTGTGCGTGT
ATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGTGTTAATGTTCTCTTGGTTTATTATGCCATCAGAATGG
TAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTTAAATAAAGGATACCACAGTGCATGCTGTTTGTTCAA
  • refseq_MYLK.F2 (forward primer)
  • refseq_MYLK.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

GAERARSPRCAPAAGAPRRAPVPRLPGRLRRAG
RILQN*QKPIRAS*REKIKVAPGCLCCSSEQLQE
LPSRELQDAFPVPLAQLPQQTTEKTVTMGDVKL
VASSHISKTSLSVDPSRVDSMPLTEAPAFILPP
RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI
TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC
EATNGSGARQVTVELTVEGSFAKQLGQPVVSKT
LGDRFSAPAVETRPSIWGECPPKFATKLGRVVVK
EGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR
VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS
GKASMSAELSIQGLDSANRSFVRETKATNSDVRK
EVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP
PWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ
KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR
PAPPRPATFPTRQPGLGSQDVVSKAANRRIPME
GQRDSAFPKFESKPQSQEVKENQTVKFRCEGLA
VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV
PRITWLLNGQPIQYARSTCEAGVAELHIQDALP
EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK
SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM
TVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRG
TQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA
VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC
AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED
VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS
LMLQNSSARALPRGREPASCEDLCGGGVGADGGG
SDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKR
RVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTK
TLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEE
RKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPK
PATPDFRSVLGGKKKLPAENGSSSAETLNAKAV
ESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAK
PAETLKPMGNAKPDENLKSASKEELKKDVKNDV
NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVH
VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK
FIILSQEGSLCSVSIEKALPEDRGLYKCVAKND
AGQAECSCQVTVDDAPASENTKAPEMKSRRPKS
SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQ
FPEDQKVRAGESVELFGKVTGTQPITCTWMKFR
KQIQESEHMKVENSENGSKLTILAARQEHCGCY
TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD
IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSAN
KTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN
VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE
KEPEVDYRTVTINTEQKVSDFYDIEERLGSGKF
GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQ
EISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVS
GGE
LFERIIDEDFELTERECIKYMRQISEGVEY
IHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGL
ARRLENAGSLKVLFGTPEFVAPEVINYEPIGYAT
DMWSIGVICYILNRLDCTQCLQHPWLMKDTKNM
EAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLS
SMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVS
QAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAA
RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY
DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATC
TAELIVETMEEGEGEGEEEEE*NKAREKQFLSH
IKRTISLKLKKKKKTQDSKST*CDRLSVRSFVG
*FFRNSS*YLAALLMGINLC*LAP*DTSAARFHL
GKSPVT*LTN*F*RESNQTKYLSGQSHKFST*M
RS*KIRPKQEFWATAQPRGFLGMGGLSLPTP*L
*RTGFSPSTPAIHF*KQLSHFIPKYTADVQTLHF
SFPFHLPVLLTLNLS*V*ALRTLCFFDSEDRSL
LMDDSGFLRKIFFFQNQ*EI*TYPLFADV*QLQ
TFG*EPMGKKKSLLMWFPL*TRILICAVIEYQL*
TCGKDFCV*I*EKSVC*KVSLNYLLATMKQIST
DKELENSMYFGISSKIARV*YIFILNTLQRT*P
TLWVPYFSS*MCINHALPPTFKYILRPGKCTQTC
VFRNF*LSFTTLALKFFLYKAF*RS*TKTIIDD
RPNTFPLCVCVTFQILFFSFPLFVRCNNLIFLR
DFLRVP*EPI*NYFSAILHSINIRILILVLCYLP
FYFYLLFAASFKLPVFFLLLLK*LQYFS**PQY
CHSLL**RVFI*FSAFKAFFYHFCVQNITFVCV
YVVCVHVWRICVLQVNAFLELC*CSLGLLCHQNG
K*EHYNCSQLTIFK*RIPQCMLFVQ

Frame 1

ALSELGARAVRLRPGRPAERRCPGSRAAFAARE
GFFKINRNQFGPAEEKK*RWLPAASAAVQSNFR
SFPAESFRTPFLSHWPSCHNKQQRRR*PWGM*SW
LPRHTFPKPPSVWIPQELTPCP*QRPLLSFCPL
GTSASKKEPPPSSKGGSGVTQSPR*HGTETGNP
SPAGAASCWIAASGGLSAL*FMLSMRRTGESIPV
KPPMAVVLAR*QWS*Q*KEVLRSSLVSLLFPKP
*GIDFQLQQWRPVLASGGSAHQSLLPSWAELWS
KKDRWDDSPARSLAGPNRRSPGSREMFHCSRVPV
CLCLRRTACRFWKSMESTKMTWECTRAWW*TGR
GRPRCQLNFPSKVWTVPIGHL*EKQKPPIQMSG
KR*PM*SQRSRSWTVWRLQPKARTAPAPREVAPH
PGLQTASLSPQGSPSWSHARTRPERPRRPRSFR
RLPAPSPCRPQEFSRNQEHQAWGSYHLLEKRGR
GQLLPVQPPSPPGSLAWGAKML*ARLLTGESPWR
ARGIQHSPNLRASPKARRSRKIKLSSSDVKGLP
*WRWPPPSPVS*RTALLLRARILCCSAPYGGPQ
CPGSLGC*MGSPSSTLAPPARPAWLSSTSRMPCR
RTMAPTPA*LRMPWGRCPAAPGSPSMKRRVAGR
VSTFCLWLPASPLHPSSCRASLISKSWMEARSL
*LSKCQGIHPLKSSGCTMGMRSKSQRTSTLNREE
LSTAFVSRKCSRRTRARTPARPGTALERSAPRP
CSRYKSLTMAPSPGSSVSLAQ*QPPWARVSSSP
AP*LVTPFLPCTGSEMAKPSAKTLATSRCFRMRT
CSPWF*RRCSPGMPASMRSCSRTGLANAVARCH
*CYRTALPEPFHGGGSLPAARTSVVEELVLMVV
VVTAMGP*GLAGQQEGRVG*RRKTARTCEGC*RG
AWRRGSTLRRRSASRRWSSWTSETSWGRR*VQR
PYRKTT*RRSQPSRWISVPTCSGK*SQRLCLRK
RGRCTAPSRSIFALSWPRRGLPRPPCLRRCHRQN
LPPRIFAQCWVARRNYQQRMAAAVPRP*MPRQW
RVPSP*AMHSLQGP*NPWATPSLLRP*SQWATP
SLPRP*SPWAMPSLMRT*NPLAKKNSRKTLRMM*
TAREAMQGPQIMKRDQRARGQPQPSSRSCKMFM
WQRARSCCSSARCLLTPQPPSSGR*TERPSRPP
SSSSSPRKAHSAPSPSRRHCLRTEAYTSV*PRMT
LARRSAPAKSPWMMLQPVRTPRPQR*NPGGPRA
LFLPC*ELRVMRL*KRNLPPRHLRRQQCPLRSS
SSLRTRRYAQESQWSCLAK*QALSPSPVPG*SSE
SRSRKAST*RWRTARMAASSPSWPRARSTAAAT
HCWWRTSWAAGRPRSTSLSWISQTPQLAHLVPL
TFGAPH*PCPGMAPHMMGAVLYSPTASRSGTQPT
RRGRN*PHAAAPLSTSRTCCLTTNISSVYVQST
CMEPVSQARSLNSQR*ERNLKSRRMKWRCQMMM
RRSPRLITGQ*QSILNKKYLTSTTLRRD*DLGNL
DRSFDL*KRKLEKSGQGSSSRHIQQKRKRISGR
RLAS*TASTTLSWSSVWMPLKKRPTSSWSWRSC
QEGS
CLSASLTRTLS*RSVSASSTCGRSRREWST
STSRASCTWTSSRRTSCVSTRRAPGSSSSTLVW
PGGWRMRGL*RSSLAPQNLWLLK*STMSPSATP
QTCGASGSSATS*TAWTARSAFSIHG**KIPRTW
RPRNSPRTG*RSTWQEGNGRKRAML*EPLEDCP
LWQ*SQGSVAGNPQQGHQPARSMQKN*NLKKMC
PKLSLRLLLRKSLM*NPISLRPFAI*KLWREVLL
DLTARLKDTQTPRLSGSKMTSQSGSPATSR*TT
MRTGTAL*LLVMFAGMTMPSTPARLSTVLEKPP
AQQSSLWKRWRKVKGKGKRKKSETKPEKSSF*VI
LKGLFL*NSKKKKKLKIVKAPSVIDYRLGHLWV
DSSETAVDT*QRY*WALIYVSWHLKILVQLDFI
*GNHQ*LD*PIDFREKVTKPNIYLGKVINSPLEC
AHEK*GQNKSSGPQLSPEGSWGWEASLSPPPDS
RELGFLPVLQQFISESS*ATLFQSTLQMFKLSI
SLSPSTCQFC*LSTCHECKH*GHYASSILKTGPC
SWMTLASLGKYFSSKISRKSKLIPSLQMSSSFR
HLVKNPWEKKNPC*CGFLCKPGFLFVLL*NISS
ERVVKIFVFEYRRNQFAEKLVLIIYWPR*NRFQL
IKSWRTPCTLESPPR*PEFNTSSFSTLSKELDL
PYGFHIFLLKCASIMPCPQPLNIFLDLVNALRL
ASLGIFNFLSLHWHLNFFFIKLFEGHKQRP*LMI
DLIHFLCVCV*HSKYFFFLFHCL*GATI*YF*G
TF*EFLKNQFKITSVQSYTVSTLEF*Y*SYVIF
HSIFICFLLLVSNCQYFSFCF*NSYNIFHDSHSI
ATVYYNKGFLFDLAHSKLFSITFVFRI*PLCAC
MLCVCMCGVYVCYRLMPSWNCVNVLLVYYAIRM
VNENTTTVVSSQFLNKGYHSACCLF

Frame 2

R*ASSEPALCACGRGAPPSAGAPAPGPPSPRGK
DSSKLTETNSGQLKRKNKGGSRLPLLQFRATSG
ASQPRASGRLSCPTGPVATTNNREDGDHGGCEA
GCLVTHFQNLPQCGSLKS*LHAPDRGPCFHFAPS
EPLHQRRSHRQVRRAGPGLPRAPGDMAQKRATH
HQRGPLPAGLRHPGDFQPCDSCCP*GGQGKVYL
*SHQWQWCSPGDSGVDSRRKFCEAAWSACCFQNL
RG*IFSSSSGDPS*HLGGVPTKVCYQAGPSCGQ
RRTDGTILLQDHWPAPTAGHLAQGKCSTAAECP
CVCV*EERHAGSGNPWSQPR*RGSVHVPGGERVG
EGLDVS*TFHPRFGQCQ*VICERNKSHQFRCQE
RGDQCNLKGVEAGQSGGCSQKQELLQPPERWLP
TLGCKQPASAPKGVQAGVMQGLAQNGPADPGPSE
DFQLHHPAGRKSSAGTKSTRPGGPITFWRREEE
ASSSPSSHLPHQAAWPGEPRCCEQGC*QENPHG
GPEGFSIPQI*EQAPKPGGQGKSNCQVQM*RACR
DGGGPLLLQCPEGLRCY*GPGFCAAVLRTGDPS
APDHLAAEWAAHPVRSLHLRGRRG*APHPGCPA
GGPWHLHLPS*ECLGAGVLQRLGHRP*KEE*QEE
*VPSACGSQQAHCTHLPAGPL*SQSHGWKPGHY
DCPSVRESTP*SHLAAQWE*DPRVRGLPL*TER
NSAQPLYPGSVPGGHGHVHLRGLEQRWRGPHPGR
AHGTRASRWHPALVHQ*ASLSDSLPGPECPHLL
RHSW*PLSYRALAQRWQSPLQRHWPLRGASE*G
RVHPGSKEGAALACRPV*DPAQEPGWRMQLPGVT
DATEQLCQSPSTGEGACQLRGPLWWRSWC*WWW
**PLWVPEAWLASKRAGLARGGRRRGRARGAEE
ARGDEAAH*GGDPPAGGGAAGLPRPPGEEGEYKD
PIGRRPEGDPSRADGFPCQPAAASEAKDCV*GR
EEGAQPPAGRFSLCPGQEGDFQDPRA*EGATAK
TCHPGFSLSAGWQEEITSREWQQQCRDPECQGSG
EFQAPEQCTAFRALETRGQRQAC*DPEANGQRQ
ACRDPEAHGQCQA**EPEIR*QRRTQERR*E*C
ELQERPCRDHR**KEIREPGDSPSLQAEAARCSC
GRGQEAAAPVPGVF*PPSHHHLDAERKDPQDHQ
VHHPLPGRLTLLRLHREGTA*GQRLIQVCSQE*
RWPGGVLLPSHRG*CSSQ*EHQGPRDEIPEAQEL
SSSRARN*E*CDCEKETCPQDTSEGSNAPSDHP
VP*GPEGTRRRVSGAVWQSDRHSAHHLYLDEVP
KADPGKRAHEGGEQREWQQAHHPGRAPGALRLLH
TAGGEQAGQQAGPGQPHCRG*ARPPSWHTLCL*
HSELLTDPVLVWLLI*WGQCCTVLQHRDLGLSQ
QDVEGTSHMPQHLFQRPGPAA*PRI*VPCTCNQR
VWNQ*AKPGV*THNGRRET*RAEG*SGGVR***
EGARG*LPDSDNQY*TKSI*LLRH*GEIRIWEI
WTGLSTCRKENSKSLGREVLQGIFSKREREYPAG
D*HHELPPPP*AGPVCGCL*RKGQHRHGPGDRV
RRG
AV*AHH*RGL*ADGA*VHQVHAADLGGSGV
HPQAGHRAPGPQAGEHHVCQQDGHQDQAHRLWSG
QEAGECGVSEGPLWHPRICGS*SDQL*AHRLRH
RHVEHRGHLLHPKPPGLHAVPSASMANERYQEH
GGQETLQGPDEEVHGKKEMAENGQCCESHWKTVL
YGNDLRAQWQEILNRVTNQPAQCRKTRI*RRCV
PSFP*GCC*GKASCKTLFL*DHSRFRSCGGKCC
*I*LQD*RIPRPRGCLVQR*PVNQGVPPLPDRLR
*GRELLFNY**CLRG*RCQVHLQGCQQSWRSHL
HSRAHCGNDGGR*RGRGRGRRVKQSQRKAVSKS
Y*KDYFSKTQKKKKNSR**KHLV**IIG*VICGL
ILQKQQLIPSSVIDGH*SMLVGTLRY*CS*ISF
REITSNLTDQLILERK*PNQIFIWAKS*ILHLN
ALMKNKAKTRVLGHSSAQRVPGDGRPLSPHPLTL
ENWVFSQYSSNSFLKAVEPLYSKVHCRCSNSPF
LFPLPPASFADSQLVMSVSIKDIMLLRF*RQVP
AHG*LWLP*ENIFLPKSVGNLNLSPLCRCLAASD
IWLRTHGKKKILANVVSFVNQDSYLCCYRISAL
NVW*RFLCLNIGEISLLKS*S*LSIGHDETDFN
**RAGELHVLWNLLQDSQSLIHLHSQHSPKNLTY
LMGSIFFFLNVHQSCLAPNL*IYS*TW*MHSDL
RL*EFLTFFHYIGT*IFSL*SFLKVINKDHN**
*T*YISSVCVCNIPNTFFFFSTVCKVQQFNIFKG
LFKSSLRTNLKLLQCNPTQYQH*NFDISLMLSS
ILFLSAFCC*FQTASIFPFAFKIVTIFFMIATV
LPQFIIIKGFYLI*RIQSFFLSLLCSEYNLCVRV
CCVCACVAYMCVTG*CLLGIVLMFSWFIMPSEW
*MRTLQL*SAHNF*IKDTTVHAVCS

Sequence NM_053026

GGCGCTGAGCGAGCTCGGAGCCCGCGCTGTGCGCCTGCGGCCGGGGCGCCCCGCCGAGCGCCGGTGCCCCGGCTCCCGGGCCGCCTTCGCCGCGCGGGAA
GGATTCTTCAAAATTAACAGAAACCAATTCGGGCCAGCTGAAGAGAAAAAATAAAGGTGGCTCCCGGCTGCCTCTGCTGCAGTTCAGAGCAACTTCAGGA
GCTTCCCAGCCGAGAGCTTCAGGACGCCTTTCCTGTCCCACTGGCCCAGTTGCCACAACAAACAACAGAGAAGACGGTGACCATGGGGGATGTGAAGCTG
GTTGCCTCGTCACACATTTCCAAAACCTCCCTCAGTGTGGATCCCTCAAGAGTTGACTCCATGCCCCTGACAGAGGCCCCTGCTTTCATTTTGCCCCCTC
GGAACCTCTGCATCAAAGAAGGAGCCACCGCCAAGTTCGAAGGGCGGGTCCGGGGTTACCCAGAGCCCCAGGTGACATGGCACAGAAACGGGCAACCCAT
CACCAGCGGGGGCCGCTTCCTGCTGGATTGCGGCATCCGGGGGACTTTCAGCCTTGTGATTCATGCTGTCCATGAGGAGGACAGGGGAAAGTATACCTGT
GAAGCCACCAATGGCAGTGGTGCTCGCCAGGTGACAGTGGAGTTGACAGTAGAAGGAAGTTTTGCGAAGCAGCTTGGTCAGCCTGTTGTTTCCAAAACCT
TAGGGGATAGATTTTCAGCTCCAGCAGTGGAGACCCGTCCTAGCATCTGGGGGGAGTGCCCACCAAAGTTTGCTACCAAGCTGGGCCGAGTTGTGGTCAA
AGAAGGACAGATGGGACGATTCTCCTGCAAGATCACTGGCCGGCCCCAACCGCAGGTCACCTGGCTCAAGGGAAATGTTCCACTGCAGCCGAGTGCCCGT
GTGTCTGTGTCTGAGAAGAACGGCATGCAGGTTCTGGAAATCCATGGAGTCAACCAAGATGACGTGGGAGTGTACACGTGCCTGGTGGTGAACGGGTCGG
GGAAGGCCTCGATGTCAGCTGAACTTTCCATCCAAGGTTTGGACAGTGCCAATAGGTCATTTGTGAGAGAAACAAAAGCCACCAATTCAGATGTCAGGAA
AGAGGTGACCAATGTAATCTCAAAGGAGTCGAAGCTGGACAGTCTGGAGGCTGCAGCCAAAAGCAAGAACTGCTCCAGCCCCCAGAGAGGTGGCTCCCCA
CCCTGGGCTGCAAACAGCCAGCCTCAGCCCCCAAGGGAGTCCAAGCTGGAGTCATGCAAGGACTCGCCCAGAACGGCCCCGCAGACCCCGGTCCTTCAGA
AGACTTCCAGCTCCATCACCCTGCAGGCCGCAAGAGTTCAGCCGGAACCAAGAGCACCAGGCCTGGGGGTCCTATCACCTTCTGGAGAAGAGAGGAAGAG
GCCAGCTCCTCCCCGTCCAGCCACCTTCCCCACCAGGCAGCCTGGCCTGGGGAGCCAAGATGTTGTGAGCAAGGCTGCTAACAGGAGAATCCCCATGGAG
GGCCAGAGGGATTCAGCATTCCCCAAATTTGAGAGCAAGCCCCAAAGCCAGGAGGTCAAGGAAAATCAAACTGTCAAGTTCAGATGTGAAGGGCTTGCCG
TGATGGAGGTGGCCCCCTCCTTCTCCAGTGTCCTGAAGGACTGCGCTGTTATTGAGGGCCAGGATTTTGTGCTGCAGTGCTCCGTACGGGGGACCCCAGT
GCCCCGGATCACTTGGCTGCTGAATGGGCAGCCCATCCAGTACGCTCGCTCCACCTGCGAGGCCGGCGTGGCTGAGCTCCACATCCAGGATGCCCTGCCG
GAGGACCATGGCACCTACACCTGCCTAGCTGAGAATGCCTTGGGGCAGGTGTCCTGCAGCGCCTGGGTCACCGTCCATGAAAAGAAGAGTAGCAGGAAGA
GTGAGTACCTTCTGCCTGTGGCTCCCAGCAAGCCCACTGCACCCATCTTCCTGCAGGGCCTCTCTGATCTCAAAGTCATGGATGGAAGCCAGGTCACTAT
GACTGTCCAAGTGTCAGGGAATCCACCCCCTGAAGTCATCTGGCTGCACAATGGGAATGAGATCCAAGAGTCAGAGGACTTCCACTTTGAACAGAGAGGA
ACTCAGCACAGCCTTTGTATCCAGGAAGTGTTCCCGGAGGACACGGGCACGTACACCTGCGAGGCCTGGAACAGCGCTGGAGAGGTCCGCACCCAGGCCG
TGCTCACGGTACAAGAGCCTCACGATGGCACCCAGCCCTGGTTCATCAGTAAGCCTCGCTCAGTGACAGCCTCCCTGGGCCAGAGTGTCCTCATCTCCTG
CGCCATAGCTGGTGACCCCTTTCCTACCGTGCACTGGCTCAGAGATGGCAAAGCCCTCTGCAAAGACACTGGCCACTTCGAGGTGCTTCAGAATGAGGAC
GTGTTCACCCTGGTTCTAAAGAAGGTGCAGCCCTGGCATGCCGGCCAGTATGAGATCCTGCTCAAGAACCGGGTTGGCGAATGCAGTTGCCAGGTGTCAC
TGATGCTACAGAACAGCTCTGCCAGAGCCCTTCCACGGGGGAGGGAGCCTGCCAGCTGCGAGGACCTCTGTGGTGGAGGAGTTGGTGCTGATGGTGGTGG
TAGTGACCGCTATGGGTCCCTGAGGCCTGGCTGGCCAGCAAGAGGGCAGGGTTGGCTAGAGGAGGAAGACGGCGAGGACGTGCGAGGGGTGCTGAAGAGG
CGCGTGGAGACGAGGCAGCACACTGAGGAGGCGATCCGCCAGCAGGAGGTGGAGCAGCTGGACTTCCGAGACCTCCTGGGGAAGAAGGTGAGTACAAAGA
CCCTATCGGAAGACGACCTGAAGGAGATCCCAGCCGAGCAGATGGATTTCCGTGCCAACCTGCAGCGGCAAGTGAAGCCAAAGACTGTGTCTGAGGAAGA
GAGGAAGGTGCACAGCCCCCAGCAGGTCGATTTTCGCTCTGTCCTGGCCAAGAAGGGGACTTCCAAGACCCCCGTGCCTGAGAAGGTGCCACCGCCAAAA
CCTGCCACCCCGGATTTTCGCTCAGTGCTGGGTGGCAAGAAGAAATTACCAGCAGAGAATGGCAGCAGCAGTGCCGAGACCCTGAATGCCAAGGCAGTGG
AGAGTTCCAAGCCCCTGAGCAATGCACAGCCTTCAGGGCCCTTGAAACCCGTGGGCAACGCCAAGCCTGCTGAGACCCTGAAGCCAATGGGCAACGCCAA
GCCTGCCGAGACCCTGAAGCCCATGGGCAATGCCAAGCCTGATGAGAACCTGAAATCCGCTAGCAAAGAAGAACTCAAGAAAGACGTTAAGAATGATGTG
AACTGCAAGAGAGGCCATGCAGGGACCACAGATAATGAAAAGAGATCAGAGAGCCAGGGGACAGCCCCAGCCTTCAAGCAGAAGCTGCAAGATGTTCATG
TGGCAGAGGGCAAGAAGCTGCTGCTCCAGTGCCAGGTGTCTTCTGACCCCCCAGCCACCATCATCTGGACGCTGAACGGAAAGACCCTCAAGACCACCAA
GTTCATCATCCTCTCCCAGGAAGGCTCACTCTGCTCCGTCTCCATCGAGAAGGCACTGCCTGAGGACAGAGGCTTATACAAGTGTGTAGCCAAGAATGAC
GCTGGCCAGGCGGAGTGCTCCTGCCAAGTCACCGTGGATGATGCTCCAGCCAGTGAGAACACCAAGGCCCCAGAGATGAAATCCCGGAGGCCCAAGAGCT
CTCTTCCTCCCGTGCTAGGAACTGAGAGTGATGCGACTGTGAAAAAGAAACCTGCCCCCAAGACACCTCCGAAGGCAGCAATGCCCCCTCAGATCATCCA
GTTCCCTGAGGACCAGAAGGTACGCGCAGGAGAGTCAGTGGAGCTGTTTGGCAAAGTGACAGGCACTCAGCCCATCACCTGTACCTGGATGAAGTTCCGA
AAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGAGAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACA
CACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCAGGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGA
CATTCGGAGCTCCTCACTGACCCTGTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAAC
AAGACGTGGAAGGAACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACG
TGTATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATGATGATGA
GAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGATTAGGATCTGGGAAATTT
GGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAGCAAAAGAGAAAGAGAATATCCGGCAGG
AGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAGAAAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTC
AGGAGGGGAG
CTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGCGTGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGTGGAGTAC
ATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGAACATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGG
CCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGGTCCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCAC
AGACATGTGGAGCATCGGGGTCATCTGCTACATCCTAGTCAGTGGCCTTTCCCCCTTCATGGGAGACAACGATAACGAAACCTTGGCCAACGTTACCTCA
GCCACCTGGGACTTCGACGACGAGGCATTCGATGAGATCTCCGACGATGCCAAGGATTTCATCAGCAATCTGCTGAAGAAAGATATGAAAAACCGCCTGG
ACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCAAGAAACTCTCCAAGGACCGGATGAAGAAGTACATGGCAAG
AAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTATGGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGG
TCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAGATGTGTCCCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAAC
CCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGTGGAGGGAAGTGCTGCTAGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTG
GTTCAAAGATGACCAGTCAATCAGGGAGTCCCGCCACTTCCAGATAGACTACGATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGAT
GACGATGCCAAGTACACCTGCAAGGCTGTCAACAGTCTTGGAGAAGCCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAG
GGGAAGAGGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAACTCA
AGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGCGTTATTGATGGGC
ATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCAGTAACTTGACTGACCAATTGATTTTAGAGAGAAA
GTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAAAAATAAGGCCAAAACAAGAGTTCTGGGCCACAGCTCA
GCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGAGAACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAG
CAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTCTCCATTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCAT
GAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTCTGAAGACAGGTCCCTGCTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAA
TCAGTAGGAAATCTAAACTTATCCCCTCTTTGCAGATGTCTAGCAGCTTCAGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGG
TTTCCTTTGTAAACCAGGATTCTTATTTGTGCTGTTATAGAATATCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTT
GCTGAAAAGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAAGAT
AGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTGCATCAATCATGCC
TTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGGAATTTTTAACTTTCTTTCACTACATTGGCACTTAAAT
TTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATACATTTCCTCTGTGTGTGTGTGTAACATTCCAAATACT
TTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACTTTTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCA
ATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTTATCTTCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTAT
TTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTCATGATAGCCACAGTATTGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTAGCGCATT
CAAAGCTTTTTTCTATCACTTTTGTGTTCAGAATATAACCTTTGTGTGCGTGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAAT
GCCTTCTTGGAATTGTGTTAATGTTCTCTTGGTTTATTATGCCATCAGAATGGTAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTTAAATAAA
GGATACCACAGTGCATGCTGTTTGTTCAA
  • refseq_MYLK.F2 (forward primer)
  • refseq_MYLK.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

GAERARSPRCAPAAGAPRRAPVPRLPGRLRRAG
RILQN*QKPIRAS*REKIKVAPGCLCCSSEQLQE
LPSRELQDAFPVPLAQLPQQTTEKTVTMGDVKL
VASSHISKTSLSVDPSRVDSMPLTEAPAFILPP
RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI
TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC
EATNGSGARQVTVELTVEGSFAKQLGQPVVSKT
LGDRFSAPAVETRPSIWGECPPKFATKLGRVVVK
EGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR
VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS
GKASMSAELSIQGLDSANRSFVRETKATNSDVRK
EVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP
PWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ
KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR
PAPPRPATFPTRQPGLGSQDVVSKAANRRIPME
GQRDSAFPKFESKPQSQEVKENQTVKFRCEGLA
VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV
PRITWLLNGQPIQYARSTCEAGVAELHIQDALP
EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK
SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM
TVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRG
TQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA
VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC
AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED
VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS
LMLQNSSARALPRGREPASCEDLCGGGVGADGGG
SDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKR
RVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTK
TLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEE
RKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPK
PATPDFRSVLGGKKKLPAENGSSSAETLNAKAV
ESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAK
PAETLKPMGNAKPDENLKSASKEELKKDVKNDV
NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVH
VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK
FIILSQEGSLCSVSIEKALPEDRGLYKCVAKND
AGQAECSCQVTVDDAPASENTKAPEMKSRRPKS
SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQ
FPEDQKVRAGESVELFGKVTGTQPITCTWMKFR
KQIQESEHMKVENSENGSKLTILAARQEHCGCY
TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD
IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSAN
KTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN
VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE
KEPEVDYRTVTINTEQKVSDFYDIEERLGSGKF
GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQ
EISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVS
GGE
LFERIIDEDFELTERECIKYMRQISEGVEY
IHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGL
ARRLENAGSLKVLFGTPEFVAPEVINYEPIGYAT
DMWSIGVICYILVSGLSPFMGDNDNETLANVTS
ATWDFDDEAFDEISDDAKDFISNLLKKDMKNRL
DCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMAR
RKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTG
SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK
PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW
FKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD
DDAKYTCKAVNSLGEATCTAELIVETMEEGEGE
GEEEEE*NKAREKQFLSHIKRTISLKLKKKKKTQ
DSKST*CDRLSVRSFVG*FFRNSS*YLAALLMG
INLC*LAP*DTSAARFHLGKSPVT*LTN*F*RE
SNQTKYLSGQSHKFST*MRS*KIRPKQEFWATAQ
PRGFLGMGGLSLPTP*L*RTGFSPSTPAIHF*K
QLSHFIPKYTADVQTLHFSFPFHLPVLLTLNLS
*V*ALRTLCFFDSEDRSLLMDDSGFLRKIFFFQN
Q*EI*TYPLFADV*QLQTFG*EPMGKKKSLLMW
FPL*TRILICAVIEYQL*TCGKDFCV*I*EKSV
C*KVSLNYLLATMKQISTDKELENSMYFGISSKI
ARV*YIFILNTLQRT*PTLWVPYFSS*MCINHA
LPPTFKYILRPGKCTQTCVFRNF*LSFTTLALK
FFLYKAF*RS*TKTIIDDRPNTFPLCVCVTFQIL
FFSFPLFVRCNNLIFLRDFLRVP*EPI*NYFSA
ILHSINIRILILVLCYLPFYFYLLFAASFKLPV
FFLLLLK*LQYFS**PQYCHSLL**RVFI*FSAF
KAFFYHFCVQNITFVCVYVVCVHVWRICVLQVN
AFLELC*CSLGLLCHQNGK*EHYNCSQLTIFK*
RIPQCMLFVQ

Frame 1

ALSELGARAVRLRPGRPAERRCPGSRAAFAARE
GFFKINRNQFGPAEEKK*RWLPAASAAVQSNFR
SFPAESFRTPFLSHWPSCHNKQQRRR*PWGM*SW
LPRHTFPKPPSVWIPQELTPCP*QRPLLSFCPL
GTSASKKEPPPSSKGGSGVTQSPR*HGTETGNP
SPAGAASCWIAASGGLSAL*FMLSMRRTGESIPV
KPPMAVVLAR*QWS*Q*KEVLRSSLVSLLFPKP
*GIDFQLQQWRPVLASGGSAHQSLLPSWAELWS
KKDRWDDSPARSLAGPNRRSPGSREMFHCSRVPV
CLCLRRTACRFWKSMESTKMTWECTRAWW*TGR
GRPRCQLNFPSKVWTVPIGHL*EKQKPPIQMSG
KR*PM*SQRSRSWTVWRLQPKARTAPAPREVAPH
PGLQTASLSPQGSPSWSHARTRPERPRRPRSFR
RLPAPSPCRPQEFSRNQEHQAWGSYHLLEKRGR
GQLLPVQPPSPPGSLAWGAKML*ARLLTGESPWR
ARGIQHSPNLRASPKARRSRKIKLSSSDVKGLP
*WRWPPPSPVS*RTALLLRARILCCSAPYGGPQ
CPGSLGC*MGSPSSTLAPPARPAWLSSTSRMPCR
RTMAPTPA*LRMPWGRCPAAPGSPSMKRRVAGR
VSTFCLWLPASPLHPSSCRASLISKSWMEARSL
*LSKCQGIHPLKSSGCTMGMRSKSQRTSTLNREE
LSTAFVSRKCSRRTRARTPARPGTALERSAPRP
CSRYKSLTMAPSPGSSVSLAQ*QPPWARVSSSP
AP*LVTPFLPCTGSEMAKPSAKTLATSRCFRMRT
CSPWF*RRCSPGMPASMRSCSRTGLANAVARCH
*CYRTALPEPFHGGGSLPAARTSVVEELVLMVV
VVTAMGP*GLAGQQEGRVG*RRKTARTCEGC*RG
AWRRGSTLRRRSASRRWSSWTSETSWGRR*VQR
PYRKTT*RRSQPSRWISVPTCSGK*SQRLCLRK
RGRCTAPSRSIFALSWPRRGLPRPPCLRRCHRQN
LPPRIFAQCWVARRNYQQRMAAAVPRP*MPRQW
RVPSP*AMHSLQGP*NPWATPSLLRP*SQWATP
SLPRP*SPWAMPSLMRT*NPLAKKNSRKTLRMM*
TAREAMQGPQIMKRDQRARGQPQPSSRSCKMFM
WQRARSCCSSARCLLTPQPPSSGR*TERPSRPP
SSSSSPRKAHSAPSPSRRHCLRTEAYTSV*PRMT
LARRSAPAKSPWMMLQPVRTPRPQR*NPGGPRA
LFLPC*ELRVMRL*KRNLPPRHLRRQQCPLRSS
SSLRTRRYAQESQWSCLAK*QALSPSPVPG*SSE
SRSRKAST*RWRTARMAASSPSWPRARSTAAAT
HCWWRTSWAAGRPRSTSLSWISQTPQLAHLVPL
TFGAPH*PCPGMAPHMMGAVLYSPTASRSGTQPT
RRGRN*PHAAAPLSTSRTCCLTTNISSVYVQST
CMEPVSQARSLNSQR*ERNLKSRRMKWRCQMMM
RRSPRLITGQ*QSILNKKYLTSTTLRRD*DLGNL
DRSFDL*KRKLEKSGQGSSSRHIQQKRKRISGR
RLAS*TASTTLSWSSVWMPLKKRPTSSWSWRSC
QEGS
CLSASLTRTLS*RSVSASSTCGRSRREWST
STSRASCTWTSSRRTSCVSTRRAPGSSSSTLVW
PGGWRMRGL*RSSLAPQNLWLLK*STMSPSATP
QTCGASGSSATS*SVAFPPSWETTITKPWPTLPQ
PPGTSTTRHSMRSPTMPRISSAIC*RKI*KTAW
TARSAFSIHG**KIPRTWRPRNSPRTG*RSTWQ
EGNGRKRAML*EPLEDCPLWQ*SQGSVAGNPQQG
HQPARSMQKN*NLKKMCPKLSLRLLLRKSLM*N
PISLRPFAI*KLWREVLLDLTARLKDTQTPRLS
GSKMTSQSGSPATSR*TTMRTGTAL*LLVMFAGM
TMPSTPARLSTVLEKPPAQQSSLWKRWRKVKGK
GKRKKSETKPEKSSF*VILKGLFL*NSKKKKKL
KIVKAPSVIDYRLGHLWVDSSETAVDT*QRY*WA
LIYVSWHLKILVQLDFI*GNHQ*LD*PIDFREK
VTKPNIYLGKVINSPLECAHEK*GQNKSSGPQL
SPEGSWGWEASLSPPPDSRELGFLPVLQQFISES
S*ATLFQSTLQMFKLSISLSPSTCQFC*LSTCH
ECKH*GHYASSILKTGPCSWMTLASLGKYFSSK
ISRKSKLIPSLQMSSSFRHLVKNPWEKKNPC*CG
FLCKPGFLFVLL*NISSERVVKIFVFEYRRNQF
AEKLVLIIYWPR*NRFQLIKSWRTPCTLESPPR
*PEFNTSSFSTLSKELDLPYGFHIFLLKCASIMP
CPQPLNIFLDLVNALRLASLGIFNFLSLHWHLN
FFFIKLFEGHKQRP*LMIDLIHFLCVCV*HSKY
FFFLFHCL*GATI*YF*GTF*EFLKNQFKITSVQ
SYTVSTLEF*Y*SYVIFHSIFICFLLLVSNCQY
FSFCF*NSYNIFHDSHSIATVYYNKGFLFDLAH
SKLFSITFVFRI*PLCACMLCVCMCGVYVCYRLM
PSWNCVNVLLVYYAIRMVNENTTTVVSSQFLNK
GYHSACCLF

Frame 2

R*ASSEPALCACGRGAPPSAGAPAPGPPSPRGK
DSSKLTETNSGQLKRKNKGGSRLPLLQFRATSG
ASQPRASGRLSCPTGPVATTNNREDGDHGGCEA
GCLVTHFQNLPQCGSLKS*LHAPDRGPCFHFAPS
EPLHQRRSHRQVRRAGPGLPRAPGDMAQKRATH
HQRGPLPAGLRHPGDFQPCDSCCP*GGQGKVYL
*SHQWQWCSPGDSGVDSRRKFCEAAWSACCFQNL
RG*IFSSSSGDPS*HLGGVPTKVCYQAGPSCGQ
RRTDGTILLQDHWPAPTAGHLAQGKCSTAAECP
CVCV*EERHAGSGNPWSQPR*RGSVHVPGGERVG
EGLDVS*TFHPRFGQCQ*VICERNKSHQFRCQE
RGDQCNLKGVEAGQSGGCSQKQELLQPPERWLP
TLGCKQPASAPKGVQAGVMQGLAQNGPADPGPSE
DFQLHHPAGRKSSAGTKSTRPGGPITFWRREEE
ASSSPSSHLPHQAAWPGEPRCCEQGC*QENPHG
GPEGFSIPQI*EQAPKPGGQGKSNCQVQM*RACR
DGGGPLLLQCPEGLRCY*GPGFCAAVLRTGDPS
APDHLAAEWAAHPVRSLHLRGRRG*APHPGCPA
GGPWHLHLPS*ECLGAGVLQRLGHRP*KEE*QEE
*VPSACGSQQAHCTHLPAGPL*SQSHGWKPGHY
DCPSVRESTP*SHLAAQWE*DPRVRGLPL*TER
NSAQPLYPGSVPGGHGHVHLRGLEQRWRGPHPGR
AHGTRASRWHPALVHQ*ASLSDSLPGPECPHLL
RHSW*PLSYRALAQRWQSPLQRHWPLRGASE*G
RVHPGSKEGAALACRPV*DPAQEPGWRMQLPGVT
DATEQLCQSPSTGEGACQLRGPLWWRSWC*WWW
**PLWVPEAWLASKRAGLARGGRRRGRARGAEE
ARGDEAAH*GGDPPAGGGAAGLPRPPGEEGEYKD
PIGRRPEGDPSRADGFPCQPAAASEAKDCV*GR
EEGAQPPAGRFSLCPGQEGDFQDPRA*EGATAK
TCHPGFSLSAGWQEEITSREWQQQCRDPECQGSG
EFQAPEQCTAFRALETRGQRQAC*DPEANGQRQ
ACRDPEAHGQCQA**EPEIR*QRRTQERR*E*C
ELQERPCRDHR**KEIREPGDSPSLQAEAARCSC
GRGQEAAAPVPGVF*PPSHHHLDAERKDPQDHQ
VHHPLPGRLTLLRLHREGTA*GQRLIQVCSQE*
RWPGGVLLPSHRG*CSSQ*EHQGPRDEIPEAQEL
SSSRARN*E*CDCEKETCPQDTSEGSNAPSDHP
VP*GPEGTRRRVSGAVWQSDRHSAHHLYLDEVP
KADPGKRAHEGGEQREWQQAHHPGRAPGALRLLH
TAGGEQAGQQAGPGQPHCRG*ARPPSWHTLCL*
HSELLTDPVLVWLLI*WGQCCTVLQHRDLGLSQ
QDVEGTSHMPQHLFQRPGPAA*PRI*VPCTCNQR
VWNQ*AKPGV*THNGRRET*RAEG*SGGVR***
EGARG*LPDSDNQY*TKSI*LLRH*GEIRIWEI
WTGLSTCRKENSKSLGREVLQGIFSKREREYPAG
D*HHELPPPP*AGPVCGCL*RKGQHRHGPGDRV
RRG
AV*AHH*RGL*ADGA*VHQVHAADLGGSGV
HPQAGHRAPGPQAGEHHVCQQDGHQDQAHRLWSG
QEAGECGVSEGPLWHPRICGS*SDQL*AHRLRH
RHVEHRGHLLHPSQWPFPLHGRQR*RNLGQRYL
SHLGLRRRGIR*DLRRCQGFHQQSAEERYEKPPG
LHAVPSASMANERYQEHGGQETLQGPDEEVHGK
KEMAENGQCCESHWKTVLYGNDLRAQWQEILNR
VTNQPAQCRKTRI*RRCVPSFP*GCC*GKASCKT
LFL*DHSRFRSCGGKCC*I*LQD*RIPRPRGCL
VQR*PVNQGVPPLPDRLR*GRELLFNY**CLRG
*RCQVHLQGCQQSWRSHLHSRAHCGNDGGR*RGR
GRGRRVKQSQRKAVSKSY*KDYFSKTQKKKKNS
R**KHLV**IIG*VICGLILQKQQLIPSSVIDG
H*SMLVGTLRY*CS*ISFREITSNLTDQLILERK
*PNQIFIWAKS*ILHLNALMKNKAKTRVLGHSS
AQRVPGDGRPLSPHPLTLENWVFSQYSSNSFLK
AVEPLYSKVHCRCSNSPFLFPLPPASFADSQLVM
SVSIKDIMLLRF*RQVPAHG*LWLP*ENIFLPK
SVGNLNLSPLCRCLAASDIWLRTHGKKKILANV
VSFVNQDSYLCCYRISALNVW*RFLCLNIGEISL
LKS*S*LSIGHDETDFN**RAGELHVLWNLLQD
SQSLIHLHSQHSPKNLTYLMGSIFFFLNVHQSC
LAPNL*IYS*TW*MHSDLRL*EFLTFFHYIGT*I
FSL*SFLKVINKDHN***T*YISSVCVCNIPNT
FFFFSTVCKVQQFNIFKGLFKSSLRTNLKLLQC
NPTQYQH*NFDISLMLSSILFLSAFCC*FQTASI
FPFAFKIVTIFFMIATVLPQFIIIKGFYLI*RI
QSFFLSLLCSEYNLCVRVCCVCACVAYMCVTG*
CLLGIVLMFSWFIMPSEW*MRTLQL*SAHNF*IK
DTTVHAVCS

Sequence NM_053027

GGCGCTGAGCGAGCTCGGAGCCCGCGCTGTGCGCCTGCGGCCGGGGCGCCCCGCCGAGCGCCGGTGCCCCGGCTCCCGGGCCGCCTTCGCCGCGCGGGAA
GGATTCTTCAAAATTAACAGAAACCAATTCGGGCCAGCTGAAGAGAAAAAATAAAGGTGGCTCCCGGCTGCCTCTGCTGCAGTTCAGAGCAACTTCAGGA
GCTTCCCAGCCGAGAGCTTCAGGACGCCTTTCCTGTCCCACTGGCCCAGTTGCCACAACAAACAACAGAGAAGACGGTGACCATGGGGGATGTGAAGCTG
GTTGCCTCGTCACACATTTCCAAAACCTCCCTCAGTGTGGATCCCTCAAGAGTTGACTCCATGCCCCTGACAGAGGCCCCTGCTTTCATTTTGCCCCCTC
GGAACCTCTGCATCAAAGAAGGAGCCACCGCCAAGTTCGAAGGGCGGGTCCGGGGTTACCCAGAGCCCCAGGTGACATGGCACAGAAACGGGCAACCCAT
CACCAGCGGGGGCCGCTTCCTGCTGGATTGCGGCATCCGGGGGACTTTCAGCCTTGTGATTCATGCTGTCCATGAGGAGGACAGGGGAAAGTATACCTGT
GAAGCCACCAATGGCAGTGGTGCTCGCCAGGTGACAGTGGAGTTGACAGTAGAAGGAAGTTTTGCGAAGCAGCTTGGTCAGCCTGTTGTTTCCAAAACCT
TAGGGGATAGATTTTCAGCTCCAGCAGTGGAGACCCGTCCTAGCATCTGGGGGGAGTGCCCACCAAAGTTTGCTACCAAGCTGGGCCGAGTTGTGGTCAA
AGAAGGACAGATGGGACGATTCTCCTGCAAGATCACTGGCCGGCCCCAACCGCAGGTCACCTGGCTCAAGGGAAATGTTCCACTGCAGCCGAGTGCCCGT
GTGTCTGTGTCTGAGAAGAACGGCATGCAGGTTCTGGAAATCCATGGAGTCAACCAAGATGACGTGGGAGTGTACACGTGCCTGGTGGTGAACGGGTCGG
GGAAGGCCTCGATGTCAGCTGAACTTTCCATCCAAGGTTTGGACAGTGCCAATAGGTCATTTGTGAGAGAAACAAAAGCCACCAATTCAGATGTCAGGAA
AGAGGTGACCAATGTAATCTCAAAGGAGTCGAAGCTGGACAGTCTGGAGGCTGCAGCCAAAAGCAAGAACTGCTCCAGCCCCCAGAGAGGTGGCTCCCCA
CCCTGGGCTGCAAACAGCCAGCCTCAGCCCCCAAGGGAGTCCAAGCTGGAGTCATGCAAGGACTCGCCCAGAACGGCCCCGCAGACCCCGGTCCTTCAGA
AGACTTCCAGCTCCATCACCCTGCAGGCCGCAAGAGTTCAGCCGGAACCAAGAGCACCAGGCCTGGGGGTCCTATCACCTTCTGGAGAAGAGAGGAAGAG
GCCAGCTCCTCCCCGTCCAGCCACCTTCCCCACCAGGCAGCCTGGCCTGGGGAGCCAAGATGTTGTGAGCAAGGCTGCTAACAGGAGAATCCCCATGGAG
GGCCAGAGGGATTCAGCATTCCCCAAATTTGAGAGCAAGCCCCAAAGCCAGGAGGTCAAGGAAAATCAAACTGTCAAGTTCAGATGTGAAGTTTCCGGGA
TTCCAAAGCCTGAAGTGGCCTGGTTCCTGGAAGGCACCCCCGTGAGGAGACAGGAAGGCAGCATTGAGGTTTATGAAGATGCTGGCTCCCATTACCTCTG
CCTGCTGAAAGCCCGGACCAGGGACAGTGGGACATACAGCTGCACTGCTTCCAACGCCCAAGGCCAGCTGTCCTGTAGCTGGACCCTCCAAGTGGAAAGG
CTTGCCGTGATGGAGGTGGCCCCCTCCTTCTCCAGTGTCCTGAAGGACTGCGCTGTTATTGAGGGCCAGGATTTTGTGCTGCAGTGCTCCGTACGGGGGA
CCCCAGTGCCCCGGATCACTTGGCTGCTGAATGGGCAGCCCATCCAGTACGCTCGCTCCACCTGCGAGGCCGGCGTGGCTGAGCTCCACATCCAGGATGC
CCTGCCGGAGGACCATGGCACCTACACCTGCCTAGCTGAGAATGCCTTGGGGCAGGTGTCCTGCAGCGCCTGGGTCACCGTCCATGAAAAGAAGAGTAGC
AGGAAGAGTGAGTACCTTCTGCCTGTGGCTCCCAGCAAGCCCACTGCACCCATCTTCCTGCAGGGCCTCTCTGATCTCAAAGTCATGGATGGAAGCCAGG
TCACTATGACTGTCCAAGTGTCAGGGAATCCACCCCCTGAAGTCATCTGGCTGCACAATGGGAATGAGATCCAAGAGTCAGAGGACTTCCACTTTGAACA
GAGAGGAACTCAGCACAGCCTTTGTATCCAGGAAGTGTTCCCGGAGGACACGGGCACGTACACCTGCGAGGCCTGGAACAGCGCTGGAGAGGTCCGCACC
CAGGCCGTGCTCACGGTACAAGAGCCTCACGATGGCACCCAGCCCTGGTTCATCAGTAAGCCTCGCTCAGTGACAGCCTCCCTGGGCCAGAGTGTCCTCA
TCTCCTGCGCCATAGCTGGTGACCCCTTTCCTACCGTGCACTGGCTCAGAGATGGCAAAGCCCTCTGCAAAGACACTGGCCACTTCGAGGTGCTTCAGAA
TGAGGACGTGTTCACCCTGGTTCTAAAGAAGGTGCAGCCCTGGCATGCCGGCCAGTATGAGATCCTGCTCAAGAACCGGGTTGGCGAATGCAGTTGCCAG
GTGTCACTGATGCTACAGAACAGCTCTGCCAGAGCCCTTCCACGGGGGAGGGAGCCTGCCAGCTGCGAGGACCTCTGTGGTGGAGGAGTTGGTGCTGATG
GTGGTGGTAGTGACCGCTATGGGTCCCTGAGGCCTGGCTGGCCAGCAAGAGGGCAGGGTTGGCTAGAGGAGGAAGACGGCGAGGACGTGCGAGGGGTGCT
GAAGAGGCGCGTGGAGACGAGGCAGCACACTGAGGAGGCGATCCGCCAGCAGGAGGTGGAGCAGCTGGACTTCCGAGACCTCCTGGGGAAGAAGGTGAGT
ACAAAGACCCTATCGGAAGACGACCTGAAGGAGATCCCAGCCGAGCAGATGGATTTCCGTGCCAACCTGCAGCGGCAAGTGAAGCCAAAGACTGTGTCTG
AGGAAGAGAGGAAGGTGCACAGCCCCCAGCAGGTCGATTTTCGCTCTGTCCTGGCCAAGAAGGGGACTTCCAAGACCCCCGTGCCTGAGAAGGTGCCACC
GCCAAAACCTGCCACCCCGGATTTTCGCTCAGTGCTGGGTGGCAAGAAGAAATTACCAGCAGAGAATGGCAGCAGCAGTGCCGAGACCCTGAATGCCAAG
GCAGTGGAGAGTTCCAAGCCCCTGAGCAATGCACAGCCTTCAGGGCCCTTGAAACCCGTGGGCAACGCCAAGCCTGCTGAGACCCTGAAGCCAATGGGCA
ACGCCAAGCCTGCCGAGACCCTGAAGCCCATGGGCAATGCCAAGCCTGATGAGAACCTGAAATCCGCTAGCAAAGAAGAACTCAAGAAAGACGTTAAGAA
TGATGTGAACTGCAAGAGAGGCCATGCAGGGACCACAGATAATGAAAAGAGATCAGAGAGCCAGGGGACAGCCCCAGCCTTCAAGCAGAAGCTGCAAGAT
GTTCATGTGGCAGAGGGCAAGAAGCTGCTGCTCCAGTGCCAGGTGTCTTCTGACCCCCCAGCCACCATCATCTGGACGCTGAACGGAAAGACCCTCAAGA
CCACCAAGTTCATCATCCTCTCCCAGGAAGGCTCACTCTGCTCCGTCTCCATCGAGAAGGCACTGCCTGAGGACAGAGGCTTATACAAGTGTGTAGCCAA
GAATGACGCTGGCCAGGCGGAGTGCTCCTGCCAAGTCACCGTGGATGATGCTCCAGCCAGTGAGAACACCAAGGCCCCAGAGATGAAATCCCGGAGGCCC
AAGAGCTCTCTTCCTCCCGTGCTAGGAACTGAGAGTGATGCGACTGTGAAAAAGAAACCTGCCCCCAAGACACCTCCGAAGGCAGCAATGCCCCCTCAGA
TCATCCAGTTCCCTGAGGACCAGAAGGTACGCGCAGGAGAGTCAGTGGAGCTGTTTGGCAAAGTGACAGGCACTCAGCCCATCACCTGTACCTGGATGAA
GTTCCGAAAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGAGAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGC
TGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCAGGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTG
CCTCTGACATTCGGAGCTCCTCACTGACCCTGTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTC
AGCCAACAAGACGTGGAAGGAACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCA
ATCAACGTGTATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATG
ATGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGATTAGGATCTGG
GAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAGCAAAAGAGAAAGAGAATATC
CGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAGAAAAGGCCAACATCGTCATGGTCCTGGAGA
TCGTGTCAGGAGGGGAG
CTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGCGTGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGT
GGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGAACATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTT
GGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGGTCCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCT
ACGCCACAGACATGTGGAGCATCGGGGTCATCTGCTACATCCTAAACCGCCTGGACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAA
GAACATGGAGGCCAAGAAACTCTCCAAGGACCGGATGAAGAAGTACATGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGA
CTGTCCTCTATGGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAG
ATGTGTCCCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGTGGAGGGAAG
TGCTGCTAGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGGAGTCCCGCCACTTCCAGATA
GACTACGATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACACCTGCAAGGCTGTCAACAGTCTTGGAGAAG
CCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAGAGGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCT
AAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAAAAACTCAAGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTT
GTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGCGTTATTGATGGGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGAT
TTCATTTAGGGAAATCACCAGTAACTTGACTGACCAATTGATTTTAGAGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCAC
TTGAATGCGCTCATGAAAAATAAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCC
TGACTCTAGAGAACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTC
TCCATTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTCTGAAGACAG
GTCCCTGCTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCCTCTTTGCAGATGTCTAGCAG
CTTCAGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCAGGATTCTTATTTGTGCTGTTATAGAATATC
AGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAAAAGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGAT
TTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCTCCAAGATAGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACT
TGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTGCATCAATCATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTC
AGACTTGCGTCTTTAGGAATTTTTAACTTTCTTTCACTACATTGGCACTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAAT
TGATGATAGACCTAATACATTTCCTCTGTGTGTGTGTGTAACATTCCAAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTT
TTAAGGGACTTTTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTT
ATCTTCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTCATGATAGCC
ACAGTATTGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTGTTCAGAATATAACCTTTGTG
TGCGTGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGTGTTAATGTTCTCTTGGTTTATTATGCCATC
AGAATGGTAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTTAAATAAAGGATACCACAGTGCATGCTGTTTGTTCAA
  • refseq_MYLK.F2 (forward primer)
  • refseq_MYLK.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

GAERARSPRCAPAAGAPRRAPVPRLPGRLRRAG
RILQN*QKPIRAS*REKIKVAPGCLCCSSEQLQE
LPSRELQDAFPVPLAQLPQQTTEKTVTMGDVKL
VASSHISKTSLSVDPSRVDSMPLTEAPAFILPP
RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI
TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC
EATNGSGARQVTVELTVEGSFAKQLGQPVVSKT
LGDRFSAPAVETRPSIWGECPPKFATKLGRVVVK
EGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR
VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS
GKASMSAELSIQGLDSANRSFVRETKATNSDVRK
EVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP
PWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ
KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR
PAPPRPATFPTRQPGLGSQDVVSKAANRRIPME
GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSG
IPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC
LLKARTRDSGTYSCTASNAQGQLSCSWTLQVER
LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG
TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA
LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS
RKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ
VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ
RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT
QAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL
ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN
EDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ
VSLMLQNSSARALPRGREPASCEDLCGGGVGAD
GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVL
KRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVS
TKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVS
EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP
PKPATPDFRSVLGGKKKLPAENGSSSAETLNAK
AVESSKPLSNAQPSGPLKPVGNAKPAETLKPMG
NAKPAETLKPMGNAKPDENLKSASKEELKKDVKN
DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQD
VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK
TTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAK
NDAGQAECSCQVTVDDAPASENTKAPEMKSRRP
KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQ
IIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK
FRKQIQESEHMKVENSENGSKLTILAARQEHCG
CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC
ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDS
ANKTWKELATCRSTSFNVQDLLPDHEYKFRVRA
INVYGTSEPSQESELTTVGEKPEEPKDEVEVSD
DDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSG
KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENI
RQEISIMNCLHHPKLVQCVDAFEEKANIVMVLE
IVSGGE
LFERIIDEDFELTERECIKYMRQISEGV
EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDF
GLARRLENAGSLKVLFGTPEFVAPEVINYEPIG
YATDMWSIGVICYILNRLDCTQCLQHPWLMKDTK
NMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGR
LSSMAMISGLSGRKSSTGSPTSPLNAEKLESEE
DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGS
AARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI
DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE
ATCTAELIVETMEEGEGEGEEEEE*NKAREKQFL
SHIKRTISLKLKKKKKTQDSKST*CDRLSVRSF
VG*FFRNSS*YLAALLMGINLC*LAP*DTSAAR
FHLGKSPVT*LTN*F*RESNQTKYLSGQSHKFST
*MRS*KIRPKQEFWATAQPRGFLGMGGLSLPTP
*L*RTGFSPSTPAIHF*KQLSHFIPKYTADVQT
LHFSFPFHLPVLLTLNLS*V*ALRTLCFFDSEDR
SLLMDDSGFLRKIFFFQNQ*EI*TYPLFADV*Q
LQTFG*EPMGKKKSLLMWFPL*TRILICAVIEY
QL*TCGKDFCV*I*EKSVC*KVSLNYLLATMKQI
STDKELENSMYFGISSKIARV*YIFILNTLQRT
*PTLWVPYFSS*MCINHALPPTFKYILRPGKCT
QTCVFRNF*LSFTTLALKFFLYKAF*RS*TKTII
DDRPNTFPLCVCVTFQILFFSFPLFVRCNNLIF
LRDFLRVP*EPI*NYFSAILHSINIRILILVLC
YLPFYFYLLFAASFKLPVFFLLLLK*LQYFS**P
QYCHSLL**RVFI*FSAFKAFFYHFCVQNITFV
CVYVVCVHVWRICVLQVNAFLELC*CSLGLLCH
QNGK*EHYNCSQLTIFK*RIPQCMLFVQ

Frame 1

ALSELGARAVRLRPGRPAERRCPGSRAAFAARE
GFFKINRNQFGPAEEKK*RWLPAASAAVQSNFR
SFPAESFRTPFLSHWPSCHNKQQRRR*PWGM*SW
LPRHTFPKPPSVWIPQELTPCP*QRPLLSFCPL
GTSASKKEPPPSSKGGSGVTQSPR*HGTETGNP
SPAGAASCWIAASGGLSAL*FMLSMRRTGESIPV
KPPMAVVLAR*QWS*Q*KEVLRSSLVSLLFPKP
*GIDFQLQQWRPVLASGGSAHQSLLPSWAELWS
KKDRWDDSPARSLAGPNRRSPGSREMFHCSRVPV
CLCLRRTACRFWKSMESTKMTWECTRAWW*TGR
GRPRCQLNFPSKVWTVPIGHL*EKQKPPIQMSG
KR*PM*SQRSRSWTVWRLQPKARTAPAPREVAPH
PGLQTASLSPQGSPSWSHARTRPERPRRPRSFR
RLPAPSPCRPQEFSRNQEHQAWGSYHLLEKRGR
GQLLPVQPPSPPGSLAWGAKML*ARLLTGESPWR
ARGIQHSPNLRASPKARRSRKIKLSSSDVKFPG
FQSLKWPGSWKAPP*GDRKAALRFMKMLAPITS
AC*KPGPGTVGHTAALLPTPKASCPVAGPSKWKG
LP*WRWPPPSPVS*RTALLLRARILCCSAPYGG
PQCPGSLGC*MGSPSSTLAPPARPAWLSSTSRM
PCRRTMAPTPA*LRMPWGRCPAAPGSPSMKRRVA
GRVSTFCLWLPASPLHPSSCRASLISKSWMEAR
SL*LSKCQGIHPLKSSGCTMGMRSKSQRTSTLN
REELSTAFVSRKCSRRTRARTPARPGTALERSAP
RPCSRYKSLTMAPSPGSSVSLAQ*QPPWARVSS
SPAP*LVTPFLPCTGSEMAKPSAKTLATSRCFR
MRTCSPWF*RRCSPGMPASMRSCSRTGLANAVAR
CH*CYRTALPEPFHGGGSLPAARTSVVEELVLM
VVVVTAMGP*GLAGQQEGRVG*RRKTARTCEGC
*RGAWRRGSTLRRRSASRRWSSWTSETSWGRR*V
QRPYRKTT*RRSQPSRWISVPTCSGK*SQRLCL
RKRGRCTAPSRSIFALSWPRRGLPRPPCLRRCH
RQNLPPRIFAQCWVARRNYQQRMAAAVPRP*MPR
QWRVPSP*AMHSLQGP*NPWATPSLLRP*SQWA
TPSLPRP*SPWAMPSLMRT*NPLAKKNSRKTLR
MM*TAREAMQGPQIMKRDQRARGQPQPSSRSCKM
FMWQRARSCCSSARCLLTPQPPSSGR*TERPSR
PPSSSSSPRKAHSAPSPSRRHCLRTEAYTSV*P
RMTLARRSAPAKSPWMMLQPVRTPRPQR*NPGGP
RALFLPC*ELRVMRL*KRNLPPRHLRRQQCPLR
SSSSLRTRRYAQESQWSCLAK*QALSPSPVPG*
SSESRSRKAST*RWRTARMAASSPSWPRARSTAA
ATHCWWRTSWAAGRPRSTSLSWISQTPQLAHLV
PLTFGAPH*PCPGMAPHMMGAVLYSPTASRSGT
QPTRRGRN*PHAAAPLSTSRTCCLTTNISSVYVQ
STCMEPVSQARSLNSQR*ERNLKSRRMKWRCQM
MMRRSPRLITGQ*QSILNKKYLTSTTLRRD*DL
GNLDRSFDL*KRKLEKSGQGSSSRHIQQKRKRIS
GRRLAS*TASTTLSWSSVWMPLKKRPTSSWSWR
SCQEGS
CLSASLTRTLS*RSVSASSTCGRSRRE
WSTSTSRASCTWTSSRRTSCVSTRRAPGSSSSTL
VWPGGWRMRGL*RSSLAPQNLWLLK*STMSPSA
TPQTCGASGSSATS*TAWTARSAFSIHG**KIP
RTWRPRNSPRTG*RSTWQEGNGRKRAML*EPLED
CPLWQ*SQGSVAGNPQQGHQPARSMQKN*NLKK
MCPKLSLRLLLRKSLM*NPISLRPFAI*KLWRE
VLLDLTARLKDTQTPRLSGSKMTSQSGSPATSR*
TTMRTGTAL*LLVMFAGMTMPSTPARLSTVLEK
PPAQQSSLWKRWRKVKGKGKRKKSETKPEKSSF
*VILKGLFL*NSKKKKKLKIVKAPSVIDYRLGHL
WVDSSETAVDT*QRY*WALIYVSWHLKILVQLD
FI*GNHQ*LD*PIDFREKVTKPNIYLGKVINSP
LECAHEK*GQNKSSGPQLSPEGSWGWEASLSPPP
DSRELGFLPVLQQFISESS*ATLFQSTLQMFKL
SISLSPSTCQFC*LSTCHECKH*GHYASSILKT
GPCSWMTLASLGKYFSSKISRKSKLIPSLQMSSS
FRHLVKNPWEKKNPC*CGFLCKPGFLFVLL*NI
SSERVVKIFVFEYRRNQFAEKLVLIIYWPR*NR
FQLIKSWRTPCTLESPPR*PEFNTSSFSTLSKEL
DLPYGFHIFLLKCASIMPCPQPLNIFLDLVNAL
RLASLGIFNFLSLHWHLNFFFIKLFEGHKQRP*
LMIDLIHFLCVCV*HSKYFFFLFHCL*GATI*YF
*GTF*EFLKNQFKITSVQSYTVSTLEF*Y*SYV
IFHSIFICFLLLVSNCQYFSFCF*NSYNIFHDS
HSIATVYYNKGFLFDLAHSKLFSITFVFRI*PLC
ACMLCVCMCGVYVCYRLMPSWNCVNVLLVYYAI
RMVNENTTTVVSSQFLNKGYHSACCLF

Frame 2

R*ASSEPALCACGRGAPPSAGAPAPGPPSPRGK
DSSKLTETNSGQLKRKNKGGSRLPLLQFRATSG
ASQPRASGRLSCPTGPVATTNNREDGDHGGCEA
GCLVTHFQNLPQCGSLKS*LHAPDRGPCFHFAPS
EPLHQRRSHRQVRRAGPGLPRAPGDMAQKRATH
HQRGPLPAGLRHPGDFQPCDSCCP*GGQGKVYL
*SHQWQWCSPGDSGVDSRRKFCEAAWSACCFQNL
RG*IFSSSSGDPS*HLGGVPTKVCYQAGPSCGQ
RRTDGTILLQDHWPAPTAGHLAQGKCSTAAECP
CVCV*EERHAGSGNPWSQPR*RGSVHVPGGERVG
EGLDVS*TFHPRFGQCQ*VICERNKSHQFRCQE
RGDQCNLKGVEAGQSGGCSQKQELLQPPERWLP
TLGCKQPASAPKGVQAGVMQGLAQNGPADPGPSE
DFQLHHPAGRKSSAGTKSTRPGGPITFWRREEE
ASSSPSSHLPHQAAWPGEPRCCEQGC*QENPHG
GPEGFSIPQI*EQAPKPGGQGKSNCQVQM*SFRD
SKA*SGLVPGRHPREETGRQH*GL*RCWLPLPL
PAESPDQGQWDIQLHCFQRPRPAVL*LDPPSGK
ACRDGGGPLLLQCPEGLRCY*GPGFCAAVLRTGD
PSAPDHLAAEWAAHPVRSLHLRGRRG*APHPGC
PAGGPWHLHLPS*ECLGAGVLQRLGHRP*KEE*
QEE*VPSACGSQQAHCTHLPAGPL*SQSHGWKPG
HYDCPSVRESTP*SHLAAQWE*DPRVRGLPL*T
ERNSAQPLYPGSVPGGHGHVHLRGLEQRWRGPH
PGRAHGTRASRWHPALVHQ*ASLSDSLPGPECPH
LLRHSW*PLSYRALAQRWQSPLQRHWPLRGASE
*GRVHPGSKEGAALACRPV*DPAQEPGWRMQLP
GVTDATEQLCQSPSTGEGACQLRGPLWWRSWC*W
WW**PLWVPEAWLASKRAGLARGGRRRGRARGA
EEARGDEAAH*GGDPPAGGGAAGLPRPPGEEGE
YKDPIGRRPEGDPSRADGFPCQPAAASEAKDCV*
GREEGAQPPAGRFSLCPGQEGDFQDPRA*EGAT
AKTCHPGFSLSAGWQEEITSREWQQQCRDPECQ
GSGEFQAPEQCTAFRALETRGQRQAC*DPEANGQ
RQACRDPEAHGQCQA**EPEIR*QRRTQERR*E
*CELQERPCRDHR**KEIREPGDSPSLQAEAAR
CSCGRGQEAAAPVPGVF*PPSHHHLDAERKDPQD
HQVHHPLPGRLTLLRLHREGTA*GQRLIQVCSQ
E*RWPGGVLLPSHRG*CSSQ*EHQGPRDEIPEA
QELSSSRARN*E*CDCEKETCPQDTSEGSNAPSD
HPVP*GPEGTRRRVSGAVWQSDRHSAHHLYLDE
VPKADPGKRAHEGGEQREWQQAHHPGRAPGALR
LLHTAGGEQAGQQAGPGQPHCRG*ARPPSWHTLC
L*HSELLTDPVLVWLLI*WGQCCTVLQHRDLGL
SQQDVEGTSHMPQHLFQRPGPAA*PRI*VPCTC
NQRVWNQ*AKPGV*THNGRRET*RAEG*SGGVR*
**EGARG*LPDSDNQY*TKSI*LLRH*GEIRIW
EIWTGLSTCRKENSKSLGREVLQGIFSKREREY
PAGD*HHELPPPP*AGPVCGCL*RKGQHRHGPGD
RVRRG
AV*AHH*RGL*ADGA*VHQVHAADLGGS
GVHPQAGHRAPGPQAGEHHVCQQDGHQDQAHRL
WSGQEAGECGVSEGPLWHPRICGS*SDQL*AHRL
RHRHVEHRGHLLHPKPPGLHAVPSASMANERYQ
EHGGQETLQGPDEEVHGKKEMAENGQCCESHWK
TVLYGNDLRAQWQEILNRVTNQPAQCRKTRI*RR
CVPSFP*GCC*GKASCKTLFL*DHSRFRSCGGK
CC*I*LQD*RIPRPRGCLVQR*PVNQGVPPLPD
RLR*GRELLFNY**CLRG*RCQVHLQGCQQSWRS
HLHSRAHCGNDGGR*RGRGRGRRVKQSQRKAVS
KSY*KDYFSKTQKKKKNSR**KHLV**IIG*VI
CGLILQKQQLIPSSVIDGH*SMLVGTLRY*CS*I
SFREITSNLTDQLILERK*PNQIFIWAKS*ILH
LNALMKNKAKTRVLGHSSAQRVPGDGRPLSPHP
LTLENWVFSQYSSNSFLKAVEPLYSKVHCRCSNS
PFLFPLPPASFADSQLVMSVSIKDIMLLRF*RQ
VPAHG*LWLP*ENIFLPKSVGNLNLSPLCRCLA
ASDIWLRTHGKKKILANVVSFVNQDSYLCCYRIS
ALNVW*RFLCLNIGEISLLKS*S*LSIGHDETD
FN**RAGELHVLWNLLQDSQSLIHLHSQHSPKN
LTYLMGSIFFFLNVHQSCLAPNL*IYS*TW*MHS
DLRL*EFLTFFHYIGT*IFSL*SFLKVINKDHN
***T*YISSVCVCNIPNTFFFFSTVCKVQQFNI
FKGLFKSSLRTNLKLLQCNPTQYQH*NFDISLML
SSILFLSAFCC*FQTASIFPFAFKIVTIFFMIA
TVLPQFIIIKGFYLI*RIQSFFLSLLCSEYNLC
VRVCCVCACVAYMCVTG*CLLGIVLMFSWFIMPS
EW*MRTLQL*SAHNF*IKDTTVHAVCS

Sequence NM_005965

TTCAGGAACCGGGTTGGCGAATGCAGTTGCCAGGTGTCACTGATGCTACAGAACAGCTCTGCCAGAGCCCTTCCACGGGGGAGGGAGCCTGCCAGCTGCG
AGGACCTCTGTGGTGGAGGAGTTGGTGCTGATGGTGGTGGTAGTGACCGCTATGGGTCCCTGAGGCCTGGCTGGCCAGCAAGAGGGCAGGGTTGGCTAGA
GGAGGAAGACGGCGAGGACGTGCGAGGGGTGCTGAAGAGGCGCGTGGAGACGAGGCAGCACACTGAGGAGGCGATCCGCCAGCAGGAGGTGGAGCAGCTG
GACTTCCGAGACCTCCTGGGGAAGAAGGTGAGTACAAAGACCCTATCGGAAGACGACCTGAAGGAGATCCCAGCCGAGCAGATGGATTTCCGTGCCAACC
TGCAGCGGCAAGTGAAGCCAAAGACTGTGTCTGAGGAAGAGAGGAAGGTGCACAGCCCCCAGCAGGTCGATTTTCGCTCTGTCCTGGCCAAGAAGGGGAC
TTCCAAGACCCCCGTGCCTGAGAAGGTGCCACCGCCAAAACCTGCCACCCCGGATTTTCGCTCAGTGCTGGGTGGCAAGAAGAAATTACCAGCAGAGAAT
GGCAGCAGCAGTGCCGAGACCCTGAATGCCAAGGCAGTGGAGAGTTCCAAGCCCCTGAGCAATGCACAGCCTTCAGGGCCCTTGAAACCCGTGGGCAACG
CCAAGCCTGCTGAGACCCTGAAGCCAATGGGCAACGCCAAGCCTGCCGAGACCCTGAAGCCCATGGGCAATGCCAAGCCTGATGAGAACCTGAAATCCGC
TAGCAAAGAAGAACTCAAGAAAGACGTTAAGAATGATGTGAACTGCAAGAGAGGCCATGCAGGGACCACAGATAATGAAAAGAGATCAGAGAGCCAGGGG
ACAGCCCCAGCCTTCAAGCAGAAGCTGCAAGATGTTCATGTGGCAGAGGGCAAGAAGCTGCTGCTCCAGTGCCAGGTGTCTTCTGACCCCCCAGCCACCA
TCATCTGGACGCTGAACGGAAAGACCCTCAAGACCACCAAGTTCATCATCCTCTCCCAGGAAGGCTCACTCTGCTCCGTCTCCATCGAGAAGGCACTGCC
TGAGGACAGAGGCTTATACAAGTGTGTAGCCAAGAATGACGCTGGCCAGGCGGAGTGCTCCTGCCAAGTCACCGTGGATGATGCTCCAGCCAGTGAGAAC
ACCAAGGCCCCAGAGATGAAATCCCGGAGGCCCAAGAGCTCTCTTCCTCCCGTGCTAGGAACTGAGAGTGATGCGACTGTGAAAAAGAAACCTGCCCCCA
AGACACCTCCGAAGGCAGCAATGCCCCCTCAGATCATCCAGTTCCCTGAGGACCAGAAGGTACGCGCAGGAGAGTCAGTGGAGCTGTTTGGCAAAGTGAC
AGGCACTCAGCCCATCACCTGTACCTGGATGAAGTTCCGAAAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGAGAATGGCAGCAAGCTC
ACCATCCTGGCCGCGCGCCAGGAGCACTGCGGCTGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCAGGCCCAGGTCAACCTCACTGTCGTGG
ATAAGCCAGACCCCCCAGCTGGCACACCTTGTGCCTCTGACATTCGGAGCTCCTCACTGACCCTGTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGC
TGTACAGTCCTACAGCATCGAGATCTGGGACTCAGCCAACAAGACGTGGAAGGAACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTG
CCTGACCACGAATATAAGTTCCGTGTACGTGCAATCAACGTGTATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTG
AAGAGCCGAAGGATGAAGTGGAGGTGTCAGATGATGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGA
CTTCTACGACATTGAGGAGAGATTAGGATCTGGGAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTC
AAGGCATATTCAGCAAAAGAGAAAGAGAATATCCGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTG
AAGAAAAGGCCAACATCGTCATGGTCCTGGAGATCGTGTCAGGAGGGGAG
CTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGCGTGAGTG
CATCAAGTACATGCGG
CAGATCTCGGAGGGAGTGGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGAACATCATGTGTGTCAAC
AAGACGGGCACCAGGATCAAGCTCATCGACTTTGGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGGTCCTCTTTGGCACCCCAGAATTTGTGG
CTCCTGAAGTGATCAACTATGAGCCCATCGGCTACGCCACAGACATGTGGAGCATCGGGGTCATCTGCTACATCCTAGTCAGTGGCCTTTCCCCCTTCAT
GGGAGACAACGATAACGAAACCTTGGCCAACGTTACCTCAGCCACCTGGGACTTCGACGACGAGGCATTCGATGAGATCTCCGACGATGCCAAGGATTTC
ATCAGCAATCTGCTGAAGAAAGATATGAAAAACCGCCTGGACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCA
AGAAACTCTCCAAGGACCGGATGAAGAAGTACATGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTATGGC
AATGATCTCAGGGCTCAGTGGCAGGAAATCCTCAACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGATGTGTCCCAAGCTTTC
CTTGAGGCTGTTGCTGAGGAAAAGCCTCATGTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGTGGAGGGAAGTGCTGCTAGATTTGACT
GCAAGATTGAAGGATACCCAGACCCCGAGGTTGTCTGGTTCAAAGATGACCAGTCAATCAGGGAGTCCCGCCACTTCCAGATAGACTACGATGAGGACGG
GAACTGCTCTTTAATTATTAGTGATGTTTGCGGGGATGACGATGCCAAGTACACCTGCAAGGCTGTCAACAGTCTTGGAGAAGCCACCTGCACAGCAGAG
CTCATTGTGGAAACGATGGAGGAAGGTGAAGGGGAAGGGGAAGAGGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCATATTAAAAGGA
CTATTTCTCTAAAACTCAAAAAAAAAAAAAAAACTCAAGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAG
AAACAGCAGTTGATACCTAGCAGCGTTATTGATGGGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCA
CCAGTAACTTGACTGACCAATTGATTTTAGAGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAA
AAATAAGGCCAAAACAAGAGTTCTGGGCCACAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGAGAACTGG
GTTTTCTCCCAGTACTCCAGCAATTCATTTCTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTCTCCATTTCTCTTTCCCC
TTCCACCTGCCAGTTTTGCTGACTCTCAACTTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTCTGAAGACAGGTCCCTGCTCATGGATG
ACTCTGGCTTCCTTAGGAAAATATTTTTCTTCCAAAATCAGTAGGAAATCTAAACTTATCCCCTCTTTGCAGATGTCTAGCAGCTTCAGACATTTGGTTA
AGAACCCATGGGAAAAAAAAAATCCTTGCTAATGTGGTTTCCTTTGTAAACCAGGATTCTTATTTGTGCTGTTATAGAATATCAGCTCTGAACGTGTGGT
AAAGATTTTTGTGTTTGAATATAGGAGAAATCAGTTTGCTGAAAAGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACTGATAAAGAGC
TGGAGAACTCCATGTACTTTGGAATCTCCTCCAAGATAGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGT
TCCATATTTTTCTTCTTAAATGTGCATCAATCATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGG
AATTTTTAACTTTCTTTCACTACATTGGCACTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATA
CATTTCCTCTGTGTGTGTGTGTAACATTCCAAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACTTTTTAAG
AGTTCCTTAAGAACCAATTTAAAATTACTTCAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTTATCTTCCATTCTATTTT
TATCTGCTTTTTGCTGCTAGTTTCAAACTGCCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTCATGATAGCCACAGTATTGCCACAGTT
TATTATAATAAAGGGTTTTTATTTGATTTAGCGCATTCAAAGCTTTTTTCTATCACTTTTGTGTTCAGAATATAACCTTTGTGTGCGTGTATGTTGTGTG
TGTGCATGTGTGGCGTATATGTGTGTTACAGGTTAATGCCTTCTTGGAATTGTGTTAATGTTCTCTTGGTTTATTATGCCATCAGAATGGTAAATGAGAA
CACTACAACTGTAGTCAGCTCACAATTTTTAAATAAAGGATACCACAGTGCATGCTGTTTGTTCAA
  • refseq_MYLK.F2 (forward primer)
  • refseq_MYLK.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

FRNRVGECSCQVSLMLQNSSARALPRGREPASC
EDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLE
EEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQL
DFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRAN
LQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT
SKTPVPEKVPPPKPATPDFRSVLGGKKKLPAEN
GSSSAETLNAKAVESSKPLSNAQPSGPLKPVGN
AKPAETLKPMGNAKPAETLKPMGNAKPDENLKSA
SKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG
TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPAT
IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALP
EDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN
TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP
KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT
GTQPITCTWMKFRKQIQESEHMKVENSENGSKL
TILAARQEHCGCYTLLVENKLGSRQAQVNLTVV
DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA
VQSYSIEIWDSANKTWKELATCRSTSFNVQDLL
PDHEYKFRVRAINVYGTSEPSQESELTTVGEKP
EEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD
FYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFF
KAYSAKEKENIRQEISIMNCLHHPKLVQCVDAF
EEKANIVMVLEIVSGGE
LFERIIDEDFELTEREC
IKYMR
QISEGVEYIHKQGIVHLDLKPENIMCVN
KTGTRIKLIDFGLARRLENAGSLKVLFGTPEFV
APEVINYEPIGYATDMWSIGVICYILVSGLSPFM
GDNDNETLANVTSATWDFDDEAFDEISDDAKDF
ISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEA
KKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMA
MISGLSGRKSSTGSPTSPLNAEKLESEDVSQAF
LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFD
CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG
NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE
LIVETMEEGEGEGEEEEE*NKAREKQFLSHIKR
TISLKLKKKKKTQDSKST*CDRLSVRSFVG*FFR
NSS*YLAALLMGINLC*LAP*DTSAARFHLGKS
PVT*LTN*F*RESNQTKYLSGQSHKFST*MRS*
KIRPKQEFWATAQPRGFLGMGGLSLPTP*L*RTG
FSPSTPAIHF*KQLSHFIPKYTADVQTLHFSFP
FHLPVLLTLNLS*V*ALRTLCFFDSEDRSLLMD
DSGFLRKIFFFQNQ*EI*TYPLFADV*QLQTFG*
EPMGKKKSLLMWFPL*TRILICAVIEYQL*TCG
KDFCV*I*EKSVC*KVSLNYLLATMKQISTDKE
LENSMYFGISSKIARV*YIFILNTLQRT*PTLWV
PYFSS*MCINHALPPTFKYILRPGKCTQTCVFR
NF*LSFTTLALKFFLYKAF*RS*TKTIIDDRPN
TFPLCVCVTFQILFFSFPLFVRCNNLIFLRDFLR
VP*EPI*NYFSAILHSINIRILILVLCYLPFYF
YLLFAASFKLPVFFLLLLK*LQYFS**PQYCHS
LL**RVFI*FSAFKAFFYHFCVQNITFVCVYVVC
VHVWRICVLQVNAFLELC*CSLGLLCHQNGK*E
HYNCSQLTIFK*RIPQCMLFVQ

Frame 1

SGTGLANAVARCH*CYRTALPEPFHGGGSLPAA
RTSVVEELVLMVVVVTAMGP*GLAGQQEGRVG*
RRKTARTCEGC*RGAWRRGSTLRRRSASRRWSSW
TSETSWGRR*VQRPYRKTT*RRSQPSRWISVPT
CSGK*SQRLCLRKRGRCTAPSRSIFALSWPRRG
LPRPPCLRRCHRQNLPPRIFAQCWVARRNYQQRM
AAAVPRP*MPRQWRVPSP*AMHSLQGP*NPWAT
PSLLRP*SQWATPSLPRP*SPWAMPSLMRT*NP
LAKKNSRKTLRMM*TAREAMQGPQIMKRDQRARG
QPQPSSRSCKMFMWQRARSCCSSARCLLTPQPP
SSGR*TERPSRPPSSSSSPRKAHSAPSPSRRHC
LRTEAYTSV*PRMTLARRSAPAKSPWMMLQPVRT
PRPQR*NPGGPRALFLPC*ELRVMRL*KRNLPP
RHLRRQQCPLRSSSSLRTRRYAQESQWSCLAK*
QALSPSPVPG*SSESRSRKAST*RWRTARMAASS
PSWPRARSTAAATHCWWRTSWAAGRPRSTSLSW
ISQTPQLAHLVPLTFGAPH*PCPGMAPHMMGAV
LYSPTASRSGTQPTRRGRN*PHAAAPLSTSRTCC
LTTNISSVYVQSTCMEPVSQARSLNSQR*ERNL
KSRRMKWRCQMMMRRSPRLITGQ*QSILNKKYL
TSTTLRRD*DLGNLDRSFDL*KRKLEKSGQGSSS
RHIQQKRKRISGRRLAS*TASTTLSWSSVWMPL
KKRPTSSWSWRSCQEGS
CLSASLTRTLS*RSVS
ASSTCG
RSRREWSTSTSRASCTWTSSRRTSCVST
RRAPGSSSSTLVWPGGWRMRGL*RSSLAPQNLW
LLK*STMSPSATPQTCGASGSSATS*SVAFPPS
WETTITKPWPTLPQPPGTSTTRHSMRSPTMPRIS
SAIC*RKI*KTAWTARSAFSIHG**KIPRTWRP
RNSPRTG*RSTWQEGNGRKRAML*EPLEDCPLW
Q*SQGSVAGNPQQGHQPARSMQKN*NLKMCPKLS
LRLLLRKSLM*NPISLRPFAI*KLWREVLLDLT
ARLKDTQTPRLSGSKMTSQSGSPATSR*TTMRT
GTAL*LLVMFAGMTMPSTPARLSTVLEKPPAQQS
SLWKRWRKVKGKGKRKKSETKPEKSSF*VILKG
LFL*NSKKKKKLKIVKAPSVIDYRLGHLWVDSS
ETAVDT*QRY*WALIYVSWHLKILVQLDFI*GNH
Q*LD*PIDFREKVTKPNIYLGKVINSPLECAHE
K*GQNKSSGPQLSPEGSWGWEASLSPPPDSREL
GFLPVLQQFISESS*ATLFQSTLQMFKLSISLSP
STCQFC*LSTCHECKH*GHYASSILKTGPCSWM
TLASLGKYFSSKISRKSKLIPSLQMSSSFRHLV
KNPWEKKNPC*CGFLCKPGFLFVLL*NISSERVV
KIFVFEYRRNQFAEKLVLIIYWPR*NRFQLIKS
WRTPCTLESPPR*PEFNTSSFSTLSKELDLPYG
FHIFLLKCASIMPCPQPLNIFLDLVNALRLASLG
IFNFLSLHWHLNFFFIKLFEGHKQRP*LMIDLI
HFLCVCV*HSKYFFFLFHCL*GATI*YF*GTF*
EFLKNQFKITSVQSYTVSTLEF*Y*SYVIFHSIF
ICFLLLVSNCQYFSFCF*NSYNIFHDSHSIATV
YYNKGFLFDLAHSKLFSITFVFRI*PLCACMLC
VCMCGVYVCYRLMPSWNCVNVLLVYYAIRMVNEN
TTTVVSSQFLNKGYHSACCLF

Frame 2

QEPGWRMQLPGVTDATEQLCQSPSTGEGACQLR
GPLWWRSWC*WWW**PLWVPEAWLASKRAGLAR
GGRRRGRARGAEEARGDEAAH*GGDPPAGGGAA
GLPRPPGEEGEYKDPIGRRPEGDPSRADGFPCQP
AAASEAKDCV*GREEGAQPPAGRFSLCPGQEGD
FQDPRA*EGATAKTCHPGFSLSAGWQEEITSRE
WQQQCRDPECQGSGEFQAPEQCTAFRALETRGQR
QAC*DPEANGQRQACRDPEAHGQCQA**EPEIR
*QRRTQERR*E*CELQERPCRDHR**KEIREPG
DSPSLQAEAARCSCGRGQEAAAPVPGVF*PPSHH
HLDAERKDPQDHQVHHPLPGRLTLLRLHREGTA
*GQRLIQVCSQE*RWPGGVLLPSHRG*CSSQ*E
HQGPRDEIPEAQELSSSRARN*E*CDCEKETCPQ
DTSEGSNAPSDHPVP*GPEGTRRRVSGAVWQSD
RHSAHHLYLDEVPKADPGKRAHEGGEQREWQQA
HHPGRAPGALRLLHTAGGEQAGQQAGPGQPHCRG
*ARPPSWHTLCL*HSELLTDPVLVWLLI*WGQC
CTVLQHRDLGLSQQDVEGTSHMPQHLFQRPGPA
A*PRI*VPCTCNQRVWNQ*AKPGV*THNGRRET*
RAEG*SGGVR***EGARG*LPDSDNQY*TKSI*
LLRH*GEIRIWEIWTGLSTCRKENSKSLGREVL
QGIFSKREREYPAGD*HHELPPPP*AGPVCGCL*
RKGQHRHGPGDRVRRG
AV*AHH*RGL*ADGA*V
HQVHA
ADLGGSGVHPQAGHRAPGPQAGEHHVCQ
QDGHQDQAHRLWSGQEAGECGVSEGPLWHPRICG
S*SDQL*AHRLRHRHVEHRGHLLHPSQWPFPLH
GRQR*RNLGQRYLSHLGLRRRGIR*DLRRCQGF
HQQSAEERYEKPPGLHAVPSASMANERYQEHGGQ
ETLQGPDEEVHGKKEMAENGQCCESHWKTVLYG
NDLRAQWQEILNRVTNQPAQCRKTRI*RCVPSF
P*GCC*GKASCKTLFL*DHSRFRSCGGKCC*I*L
QD*RIPRPRGCLVQR*PVNQGVPPLPDRLR*GR
ELLFNY**CLRG*RCQVHLQGCQQSWRSHLHSR
AHCGNDGGR*RGRGRGRRVKQSQRKAVSKSY*KD
YFSKTQKKKKNSR**KHLV**IIG*VICGLILQ
KQQLIPSSVIDGH*SMLVGTLRY*CS*ISFREI
TSNLTDQLILERK*PNQIFIWAKS*ILHLNALMK
NKAKTRVLGHSSAQRVPGDGRPLSPHPLTLENW
VFSQYSSNSFLKAVEPLYSKVHCRCSNSPFLFP
LPPASFADSQLVMSVSIKDIMLLRF*RQVPAHG*
LWLP*ENIFLPKSVGNLNLSPLCRCLAASDIWL
RTHGKKKILANVVSFVNQDSYLCCYRISALNVW
*RFLCLNIGEISLLKS*S*LSIGHDETDFN**RA
GELHVLWNLLQDSQSLIHLHSQHSPKNLTYLMG
SIFFFLNVHQSCLAPNL*IYS*TW*MHSDLRL*
EFLTFFHYIGT*IFSL*SFLKVINKDHN***T*Y
ISSVCVCNIPNTFFFFSTVCKVQQFNIFKGLFK
SSLRTNLKLLQCNPTQYQH*NFDISLMLSSILF
LSAFCC*FQTASIFPFAFKIVTIFFMIATVLPQF
IIIKGFYLI*RIQSFFLSLLCSEYNLCVRVCCV
CACVAYMCVTG*CLLGIVLMFSWFIMPSEW*MR
TLQL*SAHNF*IKDTTVHAVCS

Sequence NM_053025

GGCGCTGAGCGAGCTCGGAGCCCGCGCTGTGCGCCTGCGGCCGGGGCGCCCCGCCGAGCGCCGGTGCCCCGGCTCCCGGGCCGCCTTCGCCGCGCGGGAA
GGATTCTTCAAAATTAACAGAAACCAATTCGGGCCAGCTGAAGAGAAAAAATAAAGGTGGCTCCCGGCTGCCTCTGCTGCAGTTCAGAGCAACTTCAGGA
GCTTCCCAGCCGAGAGCTTCAGGACGCCTTTCCTGTCCCACTGGCCCAGTTGCCACAACAAACAACAGAGAAGACGGTGACCATGGGGGATGTGAAGCTG
GTTGCCTCGTCACACATTTCCAAAACCTCCCTCAGTGTGGATCCCTCAAGAGTTGACTCCATGCCCCTGACAGAGGCCCCTGCTTTCATTTTGCCCCCTC
GGAACCTCTGCATCAAAGAAGGAGCCACCGCCAAGTTCGAAGGGCGGGTCCGGGGTTACCCAGAGCCCCAGGTGACATGGCACAGAAACGGGCAACCCAT
CACCAGCGGGGGCCGCTTCCTGCTGGATTGCGGCATCCGGGGGACTTTCAGCCTTGTGATTCATGCTGTCCATGAGGAGGACAGGGGAAAGTATACCTGT
GAAGCCACCAATGGCAGTGGTGCTCGCCAGGTGACAGTGGAGTTGACAGTAGAAGGAAGTTTTGCGAAGCAGCTTGGTCAGCCTGTTGTTTCCAAAACCT
TAGGGGATAGATTTTCAGCTCCAGCAGTGGAGACCCGTCCTAGCATCTGGGGGGAGTGCCCACCAAAGTTTGCTACCAAGCTGGGCCGAGTTGTGGTCAA
AGAAGGACAGATGGGACGATTCTCCTGCAAGATCACTGGCCGGCCCCAACCGCAGGTCACCTGGCTCAAGGGAAATGTTCCACTGCAGCCGAGTGCCCGT
GTGTCTGTGTCTGAGAAGAACGGCATGCAGGTTCTGGAAATCCATGGAGTCAACCAAGATGACGTGGGAGTGTACACGTGCCTGGTGGTGAACGGGTCGG
GGAAGGCCTCGATGTCAGCTGAACTTTCCATCCAAGGTTTGGACAGTGCCAATAGGTCATTTGTGAGAGAAACAAAAGCCACCAATTCAGATGTCAGGAA
AGAGGTGACCAATGTAATCTCAAAGGAGTCGAAGCTGGACAGTCTGGAGGCTGCAGCCAAAAGCAAGAACTGCTCCAGCCCCCAGAGAGGTGGCTCCCCA
CCCTGGGCTGCAAACAGCCAGCCTCAGCCCCCAAGGGAGTCCAAGCTGGAGTCATGCAAGGACTCGCCCAGAACGGCCCCGCAGACCCCGGTCCTTCAGA
AGACTTCCAGCTCCATCACCCTGCAGGCCGCAAGAGTTCAGCCGGAACCAAGAGCACCAGGCCTGGGGGTCCTATCACCTTCTGGAGAAGAGAGGAAGAG
GCCAGCTCCTCCCCGTCCAGCCACCTTCCCCACCAGGCAGCCTGGCCTGGGGAGCCAAGATGTTGTGAGCAAGGCTGCTAACAGGAGAATCCCCATGGAG
GGCCAGAGGGATTCAGCATTCCCCAAATTTGAGAGCAAGCCCCAAAGCCAGGAGGTCAAGGAAAATCAAACTGTCAAGTTCAGATGTGAAGTTTCCGGGA
TTCCAAAGCCTGAAGTGGCCTGGTTCCTGGAAGGCACCCCCGTGAGGAGACAGGAAGGCAGCATTGAGGTTTATGAAGATGCTGGCTCCCATTACCTCTG
CCTGCTGAAAGCCCGGACCAGGGACAGTGGGACATACAGCTGCACTGCTTCCAACGCCCAAGGCCAGCTGTCCTGTAGCTGGACCCTCCAAGTGGAAAGG
CTTGCCGTGATGGAGGTGGCCCCCTCCTTCTCCAGTGTCCTGAAGGACTGCGCTGTTATTGAGGGCCAGGATTTTGTGCTGCAGTGCTCCGTACGGGGGA
CCCCAGTGCCCCGGATCACTTGGCTGCTGAATGGGCAGCCCATCCAGTACGCTCGCTCCACCTGCGAGGCCGGCGTGGCTGAGCTCCACATCCAGGATGC
CCTGCCGGAGGACCATGGCACCTACACCTGCCTAGCTGAGAATGCCTTGGGGCAGGTGTCCTGCAGCGCCTGGGTCACCGTCCATGAAAAGAAGAGTAGC
AGGAAGAGTGAGTACCTTCTGCCTGTGGCTCCCAGCAAGCCCACTGCACCCATCTTCCTGCAGGGCCTCTCTGATCTCAAAGTCATGGATGGAAGCCAGG
TCACTATGACTGTCCAAGTGTCAGGGAATCCACCCCCTGAAGTCATCTGGCTGCACAATGGGAATGAGATCCAAGAGTCAGAGGACTTCCACTTTGAACA
GAGAGGAACTCAGCACAGCCTTTGTATCCAGGAAGTGTTCCCGGAGGACACGGGCACGTACACCTGCGAGGCCTGGAACAGCGCTGGAGAGGTCCGCACC
CAGGCCGTGCTCACGGTACAAGAGCCTCACGATGGCACCCAGCCCTGGTTCATCAGTAAGCCTCGCTCAGTGACAGCCTCCCTGGGCCAGAGTGTCCTCA
TCTCCTGCGCCATAGCTGGTGACCCCTTTCCTACCGTGCACTGGCTCAGAGATGGCAAAGCCCTCTGCAAAGACACTGGCCACTTCGAGGTGCTTCAGAA
TGAGGACGTGTTCACCCTGGTTCTAAAGAAGGTGCAGCCCTGGCATGCCGGCCAGTATGAGATCCTGCTCAAGAACCGGGTTGGCGAATGCAGTTGCCAG
GTGTCACTGATGCTACAGAACAGCTCTGCCAGAGCCCTTCCACGGGGGAGGGAGCCTGCCAGCTGCGAGGACCTCTGTGGTGGAGGAGTTGGTGCTGATG
GTGGTGGTAGTGACCGCTATGGGTCCCTGAGGCCTGGCTGGCCAGCAAGAGGGCAGGGTTGGCTAGAGGAGGAAGACGGCGAGGACGTGCGAGGGGTGCT
GAAGAGGCGCGTGGAGACGAGGCAGCACACTGAGGAGGCGATCCGCCAGCAGGAGGTGGAGCAGCTGGACTTCCGAGACCTCCTGGGGAAGAAGGTGAGT
ACAAAGACCCTATCGGAAGACGACCTGAAGGAGATCCCAGCCGAGCAGATGGATTTCCGTGCCAACCTGCAGCGGCAAGTGAAGCCAAAGACTGTGTCTG
AGGAAGAGAGGAAGGTGCACAGCCCCCAGCAGGTCGATTTTCGCTCTGTCCTGGCCAAGAAGGGGACTTCCAAGACCCCCGTGCCTGAGAAGGTGCCACC
GCCAAAACCTGCCACCCCGGATTTTCGCTCAGTGCTGGGTGGCAAGAAGAAATTACCAGCAGAGAATGGCAGCAGCAGTGCCGAGACCCTGAATGCCAAG
GCAGTGGAGAGTTCCAAGCCCCTGAGCAATGCACAGCCTTCAGGGCCCTTGAAACCCGTGGGCAACGCCAAGCCTGCTGAGACCCTGAAGCCAATGGGCA
ACGCCAAGCCTGCCGAGACCCTGAAGCCCATGGGCAATGCCAAGCCTGATGAGAACCTGAAATCCGCTAGCAAAGAAGAACTCAAGAAAGACGTTAAGAA
TGATGTGAACTGCAAGAGAGGCCATGCAGGGACCACAGATAATGAAAAGAGATCAGAGAGCCAGGGGACAGCCCCAGCCTTCAAGCAGAAGCTGCAAGAT
GTTCATGTGGCAGAGGGCAAGAAGCTGCTGCTCCAGTGCCAGGTGTCTTCTGACCCCCCAGCCACCATCATCTGGACGCTGAACGGAAAGACCCTCAAGA
CCACCAAGTTCATCATCCTCTCCCAGGAAGGCTCACTCTGCTCCGTCTCCATCGAGAAGGCACTGCCTGAGGACAGAGGCTTATACAAGTGTGTAGCCAA
GAATGACGCTGGCCAGGCGGAGTGCTCCTGCCAAGTCACCGTGGATGATGCTCCAGCCAGTGAGAACACCAAGGCCCCAGAGATGAAATCCCGGAGGCCC
AAGAGCTCTCTTCCTCCCGTGCTAGGAACTGAGAGTGATGCGACTGTGAAAAAGAAACCTGCCCCCAAGACACCTCCGAAGGCAGCAATGCCCCCTCAGA
TCATCCAGTTCCCTGAGGACCAGAAGGTACGCGCAGGAGAGTCAGTGGAGCTGTTTGGCAAAGTGACAGGCACTCAGCCCATCACCTGTACCTGGATGAA
GTTCCGAAAGCAGATCCAGGAAAGCGAGCACATGAAGGTGGAGAACAGCGAGAATGGCAGCAAGCTCACCATCCTGGCCGCGCGCCAGGAGCACTGCGGC
TGCTACACACTGCTGGTGGAGAACAAGCTGGGCAGCAGGCAGGCCCAGGTCAACCTCACTGTCGTGGATAAGCCAGACCCCCCAGCTGGCACACCTTGTG
CCTCTGACATTCGGAGCTCCTCACTGACCCTGTCCTGGTATGGCTCCTCATATGATGGGGGCAGTGCTGTACAGTCCTACAGCATCGAGATCTGGGACTC
AGCCAACAAGACGTGGAAGGAACTAGCCACATGCCGCAGCACCTCTTTCAACGTCCAGGACCTGCTGCCTGACCACGAATATAAGTTCCGTGTACGTGCA
ATCAACGTGTATGGAACCAGTGAGCCAAGCCAGGAGTCTGAACTCACAACGGTAGGAGAGAAACCTGAAGAGCCGAAGGATGAAGTGGAGGTGTCAGATG
ATGATGAGAAGGAGCCCGAGGTTGATTACCGGACAGTGACAATCAATACTGAACAAAAAGTATCTGACTTCTACGACATTGAGGAGAGATTAGGATCTGG
GAAATTTGGACAGGTCTTTCGACTTGTAGAAAAGAAAACTCGAAAAGTCTGGGCAGGGAAGTTCTTCAAGGCATATTCAGCAAAAGAGAAAGAGAATATC
CGGCAGGAGATTAGCATCATGAACTGCCTCCACCACCCTAAGCTGGTCCAGTGTGTGGATGCCTTTGAAGAAAAGGCCAACATCGTCATGGTCCTGGAGA
TCGTGTCAGGAGGGGAG
CTGTTTGAGCGCATCATTGACGAGGACTTTGAGCTGACGGAGCGTGAGTGCATCAAGTACATGCGGCAGATCTCGGAGGGAGT
GGAGTACATCCACAAGCAGGGCATCGTGCACCTGGACCTCAAGCCGGAGAACATCATGTGTGTCAACAAGACGGGCACCAGGATCAAGCTCATCGACTTT
GGTCTGGCCAGGAGGCTGGAGAATGCGGGGTCTCTGAAGGTCCTCTTTGGCACCCCAGAATTTGTGGCTCCTGAAGTGATCAACTATGAGCCCATCGGCT
ACGCCACAGACATGTGGAGCATCGGGGTCATCTGCTACATCCTAGTCAGTGGCCTTTCCCCCTTCATGGGAGACAACGATAACGAAACCTTGGCCAACGT
TACCTCAGCCACCTGGGACTTCGACGACGAGGCATTCGATGAGATCTCCGACGATGCCAAGGATTTCATCAGCAATCTGCTGAAGAAAGATATGAAAAAC
CGCCTGGACTGCACGCAGTGCCTTCAGCATCCATGGCTAATGAAAGATACCAAGAACATGGAGGCCAAGAAACTCTCCAAGGACCGGATGAAGAAGTACA
TGGCAAGAAGGAAATGGCAGAAAACGGGCAATGCTGTGAGAGCCATTGGAAGACTGTCCTCTATGGCAATGATCTCAGGGCTCAGTGGCAGGAAATCCTC
AACAGGGTCACCAACCAGCCCGCTCAATGCAGAAAAACTAGAATCTGAAGAAGATGTGTCCCAAGCTTTCCTTGAGGCTGTTGCTGAGGAAAAGCCTCAT
GTAAAACCCTATTTCTCTAAGACCATTCGCGATTTAGAAGTTGTGGAGGGAAGTGCTGCTAGATTTGACTGCAAGATTGAAGGATACCCAGACCCCGAGG
TTGTCTGGTTCAAAGATGACCAGTCAATCAGGGAGTCCCGCCACTTCCAGATAGACTACGATGAGGACGGGAACTGCTCTTTAATTATTAGTGATGTTTG
CGGGGATGACGATGCCAAGTACACCTGCAAGGCTGTCAACAGTCTTGGAGAAGCCACCTGCACAGCAGAGCTCATTGTGGAAACGATGGAGGAAGGTGAA
GGGGAAGGGGAAGAGGAAGAAGAGTGAAACAAAGCCAGAGAAAAGCAGTTTCTAAGTCATATTAAAAGGACTATTTCTCTAAAACTCAAAAAAAAAAAAA
AAACTCAAGATAGTAAAAGCACCTAGTGTGATAGATTATCGGTTAGGTCATTTGTGGGTTGATTCTTCAGAAACAGCAGTTGATACCTAGCAGCGTTATT
GATGGGCATTAATCTATGTTAGTTGGCACCTTAAGATACTAGTGCAGCTAGATTTCATTTAGGGAAATCACCAGTAACTTGACTGACCAATTGATTTTAG
AGAGAAAGTAACCAAACCAAATATTTATCTGGGCAAAGTCATAAATTCTCCACTTGAATGCGCTCATGAAAAATAAGGCCAAAACAAGAGTTCTGGGCCA
CAGCTCAGCCCAGAGGGTTCCTGGGGATGGGAGGCCTCTCTCTCCCCACCCCCTGACTCTAGAGAACTGGGTTTTCTCCCAGTACTCCAGCAATTCATTT
CTGAAAGCAGTTGAGCCACTTTATTCCAAAGTACACTGCAGATGTTCAAACTCTCCATTTCTCTTTCCCCTTCCACCTGCCAGTTTTGCTGACTCTCAAC
TTGTCATGAGTGTAAGCATTAAGGACATTATGCTTCTTCGATTCTGAAGACAGGTCCCTGCTCATGGATGACTCTGGCTTCCTTAGGAAAATATTTTTCT
TCCAAAATCAGTAGGAAATCTAAACTTATCCCCTCTTTGCAGATGTCTAGCAGCTTCAGACATTTGGTTAAGAACCCATGGGAAAAAAAAAATCCTTGCT
AATGTGGTTTCCTTTGTAAACCAGGATTCTTATTTGTGCTGTTATAGAATATCAGCTCTGAACGTGTGGTAAAGATTTTTGTGTTTGAATATAGGAGAAA
TCAGTTTGCTGAAAAGTTAGTCTTAATTATCTATTGGCCACGATGAAACAGATTTCAACTGATAAAGAGCTGGAGAACTCCATGTACTTTGGAATCTCCT
CCAAGATAGCCAGAGTTTAATACATCTTCATTCTCAACACTCTCCAAAGAACTTGACCTACCTTATGGGTTCCATATTTTTCTTCTTAAATGTGCATCAA
TCATGCCTTGCCCCCAACCTTTAAATATATTCTTAGACCTGGTAAATGCACTCAGACTTGCGTCTTTAGGAATTTTTAACTTTCTTTCACTACATTGGCA
CTTAAATTTTTTCTTTATAAAGCTTTTTGAAGGTCATAAACAAAGACCATAATTGATGATAGACCTAATACATTTCCTCTGTGTGTGTGTGTAACATTCC
AAATACTTTTTTTTTCTTTTCCACTGTTTGTAAGGTGCAACAATTTAATATTTTTAAGGGACTTTTTAAGAGTTCCTTAAGAACCAATTTAAAATTACTT
CAGTGCAATCCTACACAGTATCAACATTAGAATTTTGATATTAGTCTTATGTTATCTTCCATTCTATTTTTATCTGCTTTTTGCTGCTAGTTTCAAACTG
CCAGTATTTTTCCTTTTGCTTTTAAAATAGTTACAATATTTTTCATGATAGCCACAGTATTGCCACAGTTTATTATAATAAAGGGTTTTTATTTGATTTA
GCGCATTCAAAGCTTTTTTCTATCACTTTTGTGTTCAGAATATAACCTTTGTGTGCGTGTATGTTGTGTGTGTGCATGTGTGGCGTATATGTGTGTTACA
GGTTAATGCCTTCTTGGAATTGTGTTAATGTTCTCTTGGTTTATTATGCCATCAGAATGGTAAATGAGAACACTACAACTGTAGTCAGCTCACAATTTTT
AAATAAAGGATACCACAGTGCATGCTGTTTGTTCAA
  • refseq_MYLK.F2 (forward primer)
  • refseq_MYLK.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

GAERARSPRCAPAAGAPRRAPVPRLPGRLRRAG
RILQN*QKPIRAS*REKIKVAPGCLCCSSEQLQE
LPSRELQDAFPVPLAQLPQQTTEKTVTMGDVKL
VASSHISKTSLSVDPSRVDSMPLTEAPAFILPP
RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI
TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC
EATNGSGARQVTVELTVEGSFAKQLGQPVVSKT
LGDRFSAPAVETRPSIWGECPPKFATKLGRVVVK
EGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR
VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS
GKASMSAELSIQGLDSANRSFVRETKATNSDVRK
EVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP
PWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ
KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR
PAPPRPATFPTRQPGLGSQDVVSKAANRRIPME
GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSG
IPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC
LLKARTRDSGTYSCTASNAQGQLSCSWTLQVER
LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG
TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA
LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS
RKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ
VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ
RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT
QAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL
ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN
EDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ
VSLMLQNSSARALPRGREPASCEDLCGGGVGAD
GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVL
KRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVS
TKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVS
EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP
PKPATPDFRSVLGGKKKLPAENGSSSAETLNAK
AVESSKPLSNAQPSGPLKPVGNAKPAETLKPMG
NAKPAETLKPMGNAKPDENLKSASKEELKKDVKN
DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQD
VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK
TTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAK
NDAGQAECSCQVTVDDAPASENTKAPEMKSRRP
KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQ
IIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK
FRKQIQESEHMKVENSENGSKLTILAARQEHCG
CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC
ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDS
ANKTWKELATCRSTSFNVQDLLPDHEYKFRVRA
INVYGTSEPSQESELTTVGEKPEEPKDEVEVSD
DDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSG
KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENI
RQEISIMNCLHHPKLVQCVDAFEEKANIVMVLE
IVSGGE
LFERIIDEDFELTERECIKYMRQISEGV
EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDF
GLARRLENAGSLKVLFGTPEFVAPEVINYEPIG
YATDMWSIGVICYILVSGLSPFMGDNDNETLANV
TSATWDFDDEAFDEISDDAKDFISNLLKKDMKN
RLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKY
MARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSS
TGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPH
VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE
VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC
GDDDAKYTCKAVNSLGEATCTAELIVETMEEGE
GEGEEEEE*NKAREKQFLSHIKRTISLKLKKKK
KTQDSKST*CDRLSVRSFVG*FFRNSS*YLAALL
MGINLC*LAP*DTSAARFHLGKSPVT*LTN*F*
RESNQTKYLSGQSHKFST*MRS*KIRPKQEFWA
TAQPRGFLGMGGLSLPTP*L*RTGFSPSTPAIHF
*KQLSHFIPKYTADVQTLHFSFPFHLPVLLTLN
LS*V*ALRTLCFFDSEDRSLLMDDSGFLRKIFF
FQNQ*EI*TYPLFADV*QLQTFG*EPMGKKKSLL
MWFPL*TRILICAVIEYQL*TCGKDFCV*I*EK
SVC*KVSLNYLLATMKQISTDKELENSMYFGIS
SKIARV*YIFILNTLQRT*PTLWVPYFSS*MCIN
HALPPTFKYILRPGKCTQTCVFRNF*LSFTTLA
LKFFLYKAF*RS*TKTIIDDRPNTFPLCVCVTF
QILFFSFPLFVRCNNLIFLRDFLRVP*EPI*NYF
SAILHSINIRILILVLCYLPFYFYLLFAASFKL
PVFFLLLLK*LQYFS**PQYCHSLL**RVFI*F
SAFKAFFYHFCVQNITFVCVYVVCVHVWRICVLQ
VNAFLELC*CSLGLLCHQNGK*EHYNCSQLTIF
K*RIPQCMLFVQ

Frame 1

ALSELGARAVRLRPGRPAERRCPGSRAAFAARE
GFFKINRNQFGPAEEKK*RWLPAASAAVQSNFR
SFPAESFRTPFLSHWPSCHNKQQRRR*PWGM*SW
LPRHTFPKPPSVWIPQELTPCP*QRPLLSFCPL
GTSASKKEPPPSSKGGSGVTQSPR*HGTETGNP
SPAGAASCWIAASGGLSAL*FMLSMRRTGESIPV
KPPMAVVLAR*QWS*Q*KEVLRSSLVSLLFPKP
*GIDFQLQQWRPVLASGGSAHQSLLPSWAELWS
KKDRWDDSPARSLAGPNRRSPGSREMFHCSRVPV
CLCLRRTACRFWKSMESTKMTWECTRAWW*TGR
GRPRCQLNFPSKVWTVPIGHL*EKQKPPIQMSG
KR*PM*SQRSRSWTVWRLQPKARTAPAPREVAPH
PGLQTASLSPQGSPSWSHARTRPERPRRPRSFR
RLPAPSPCRPQEFSRNQEHQAWGSYHLLEKRGR
GQLLPVQPPSPPGSLAWGAKML*ARLLTGESPWR
ARGIQHSPNLRASPKARRSRKIKLSSSDVKFPG
FQSLKWPGSWKAPP*GDRKAALRFMKMLAPITS
AC*KPGPGTVGHTAALLPTPKASCPVAGPSKWKG
LP*WRWPPPSPVS*RTALLLRARILCCSAPYGG
PQCPGSLGC*MGSPSSTLAPPARPAWLSSTSRM
PCRRTMAPTPA*LRMPWGRCPAAPGSPSMKRRVA
GRVSTFCLWLPASPLHPSSCRASLISKSWMEAR
SL*LSKCQGIHPLKSSGCTMGMRSKSQRTSTLN
REELSTAFVSRKCSRRTRARTPARPGTALERSAP
RPCSRYKSLTMAPSPGSSVSLAQ*QPPWARVSS
SPAP*LVTPFLPCTGSEMAKPSAKTLATSRCFR
MRTCSPWF*RRCSPGMPASMRSCSRTGLANAVAR
CH*CYRTALPEPFHGGGSLPAARTSVVEELVLM
VVVVTAMGP*GLAGQQEGRVG*RRKTARTCEGC
*RGAWRRGSTLRRRSASRRWSSWTSETSWGRR*V
QRPYRKTT*RRSQPSRWISVPTCSGK*SQRLCL
RKRGRCTAPSRSIFALSWPRRGLPRPPCLRRCH
RQNLPPRIFAQCWVARRNYQQRMAAAVPRP*MPR
QWRVPSP*AMHSLQGP*NPWATPSLLRP*SQWA
TPSLPRP*SPWAMPSLMRT*NPLAKKNSRKTLR
MM*TAREAMQGPQIMKRDQRARGQPQPSSRSCKM
FMWQRARSCCSSARCLLTPQPPSSGR*TERPSR
PPSSSSSPRKAHSAPSPSRRHCLRTEAYTSV*P
RMTLARRSAPAKSPWMMLQPVRTPRPQR*NPGGP
RALFLPC*ELRVMRL*KRNLPPRHLRRQQCPLR
SSSSLRTRRYAQESQWSCLAK*QALSPSPVPG*
SSESRSRKAST*RWRTARMAASSPSWPRARSTAA
ATHCWWRTSWAAGRPRSTSLSWISQTPQLAHLV
PLTFGAPH*PCPGMAPHMMGAVLYSPTASRSGT
QPTRRGRN*PHAAAPLSTSRTCCLTTNISSVYVQ
STCMEPVSQARSLNSQR*ERNLKSRRMKWRCQM
MMRRSPRLITGQ*QSILNKKYLTSTTLRRD*DL
GNLDRSFDL*KRKLEKSGQGSSSRHIQQKRKRIS
GRRLAS*TASTTLSWSSVWMPLKKRPTSSWSWR
SCQEGS
CLSASLTRTLS*RSVSASSTCGRSRRE
WSTSTSRASCTWTSSRRTSCVSTRRAPGSSSSTL
VWPGGWRMRGL*RSSLAPQNLWLLK*STMSPSA
TPQTCGASGSSATS*SVAFPPSWETTITKPWPT
LPQPPGTSTTRHSMRSPTMPRISSAIC*RKI*KT
AWTARSAFSIHG**KIPRTWRPRNSPRTG*RST
WQEGNGRKRAML*EPLEDCPLWQ*SQGSVAGNP
QQGHQPARSMQKN*NLKKMCPKLSLRLLLRKSLM
*NPISLRPFAI*KLWREVLLDLTARLKDTQTPR
LSGSKMTSQSGSPATSR*TTMRTGTAL*LLVMF
AGMTMPSTPARLSTVLEKPPAQQSSLWKRWRKVK
GKGKRKKSETKPEKSSF*VILKGLFL*NSKKKK
KLKIVKAPSVIDYRLGHLWVDSSETAVDT*QRY
*WALIYVSWHLKILVQLDFI*GNHQ*LD*PIDFR
EKVTKPNIYLGKVINSPLECAHEK*GQNKSSGP
QLSPEGSWGWEASLSPPPDSRELGFLPVLQQFI
SESS*ATLFQSTLQMFKLSISLSPSTCQFC*LST
CHECKH*GHYASSILKTGPCSWMTLASLGKYFS
SKISRKSKLIPSLQMSSSFRHLVKNPWEKKNPC
*CGFLCKPGFLFVLL*NISSERVVKIFVFEYRRN
QFAEKLVLIIYWPR*NRFQLIKSWRTPCTLESP
PR*PEFNTSSFSTLSKELDLPYGFHIFLLKCAS
IMPCPQPLNIFLDLVNALRLASLGIFNFLSLHWH
LNFFFIKLFEGHKQRP*LMIDLIHFLCVCV*HS
KYFFFLFHCL*GATI*YF*GTF*EFLKNQFKIT
SVQSYTVSTLEF*Y*SYVIFHSIFICFLLLVSNC
QYFSFCF*NSYNIFHDSHSIATVYYNKGFLFDL
AHSKLFSITFVFRI*PLCACMLCVCMCGVYVCY
RLMPSWNCVNVLLVYYAIRMVNENTTTVVSSQFL
NKGYHSACCLF

Frame 2

R*ASSEPALCACGRGAPPSAGAPAPGPPSPRGK
DSSKLTETNSGQLKRKNKGGSRLPLLQFRATSG
ASQPRASGRLSCPTGPVATTNNREDGDHGGCEA
GCLVTHFQNLPQCGSLKS*LHAPDRGPCFHFAPS
EPLHQRRSHRQVRRAGPGLPRAPGDMAQKRATH
HQRGPLPAGLRHPGDFQPCDSCCP*GGQGKVYL
*SHQWQWCSPGDSGVDSRRKFCEAAWSACCFQNL
RG*IFSSSSGDPS*HLGGVPTKVCYQAGPSCGQ
RRTDGTILLQDHWPAPTAGHLAQGKCSTAAECP
CVCV*EERHAGSGNPWSQPR*RGSVHVPGGERVG
EGLDVS*TFHPRFGQCQ*VICERNKSHQFRCQE
RGDQCNLKGVEAGQSGGCSQKQELLQPPERWLP
TLGCKQPASAPKGVQAGVMQGLAQNGPADPGPSE
DFQLHHPAGRKSSAGTKSTRPGGPITFWRREEE
ASSSPSSHLPHQAAWPGEPRCCEQGC*QENPHG
GPEGFSIPQI*EQAPKPGGQGKSNCQVQM*SFRD
SKA*SGLVPGRHPREETGRQH*GL*RCWLPLPL
PAESPDQGQWDIQLHCFQRPRPAVL*LDPPSGK
ACRDGGGPLLLQCPEGLRCY*GPGFCAAVLRTGD
PSAPDHLAAEWAAHPVRSLHLRGRRG*APHPGC
PAGGPWHLHLPS*ECLGAGVLQRLGHRP*KEE*
QEE*VPSACGSQQAHCTHLPAGPL*SQSHGWKPG
HYDCPSVRESTP*SHLAAQWE*DPRVRGLPL*T
ERNSAQPLYPGSVPGGHGHVHLRGLEQRWRGPH
PGRAHGTRASRWHPALVHQ*ASLSDSLPGPECPH
LLRHSW*PLSYRALAQRWQSPLQRHWPLRGASE
*GRVHPGSKEGAALACRPV*DPAQEPGWRMQLP
GVTDATEQLCQSPSTGEGACQLRGPLWWRSWC*W
WW**PLWVPEAWLASKRAGLARGGRRRGRARGA
EEARGDEAAH*GGDPPAGGGAAGLPRPPGEEGE
YKDPIGRRPEGDPSRADGFPCQPAAASEAKDCV*
GREEGAQPPAGRFSLCPGQEGDFQDPRA*EGAT
AKTCHPGFSLSAGWQEEITSREWQQQCRDPECQ
GSGEFQAPEQCTAFRALETRGQRQAC*DPEANGQ
RQACRDPEAHGQCQA**EPEIR*QRRTQERR*E
*CELQERPCRDHR**KEIREPGDSPSLQAEAAR
CSCGRGQEAAAPVPGVF*PPSHHHLDAERKDPQD
HQVHHPLPGRLTLLRLHREGTA*GQRLIQVCSQ
E*RWPGGVLLPSHRG*CSSQ*EHQGPRDEIPEA
QELSSSRARN*E*CDCEKETCPQDTSEGSNAPSD
HPVP*GPEGTRRRVSGAVWQSDRHSAHHLYLDE
VPKADPGKRAHEGGEQREWQQAHHPGRAPGALR
LLHTAGGEQAGQQAGPGQPHCRG*ARPPSWHTLC
L*HSELLTDPVLVWLLI*WGQCCTVLQHRDLGL
SQQDVEGTSHMPQHLFQRPGPAA*PRI*VPCTC
NQRVWNQ*AKPGV*THNGRRET*RAEG*SGGVR*
**EGARG*LPDSDNQY*TKSI*LLRH*GEIRIW
EIWTGLSTCRKENSKSLGREVLQGIFSKREREY
PAGD*HHELPPPP*AGPVCGCL*RKGQHRHGPGD
RVRRG
AV*AHH*RGL*ADGA*VHQVHAADLGGS
GVHPQAGHRAPGPQAGEHHVCQQDGHQDQAHRL
WSGQEAGECGVSEGPLWHPRICGS*SDQL*AHRL
RHRHVEHRGHLLHPSQWPFPLHGRQR*RNLGQR
YLSHLGLRRRGIR*DLRRCQGFHQQSAEERYEK
PPGLHAVPSASMANERYQEHGGQETLQGPDEEVH
GKKEMAENGQCCESHWKTVLYGNDLRAQWQEIL
NRVTNQPAQCRKTRI*RRCVPSFP*GCC*GKAS
CKTLFL*DHSRFRSCGGKCC*I*LQD*RIPRPRG
CLVQR*PVNQGVPPLPDRLR*GRELLFNY**CL
RG*RCQVHLQGCQQSWRSHLHSRAHCGNDGGR*
RGRGRGRRVKQSQRKAVSKSY*KDYFSKTQKKKK
NSR**KHLV**IIG*VICGLILQKQQLIPSSVI
DGH*SMLVGTLRY*CS*ISFREITSNLTDQLIL
ERK*PNQIFIWAKS*ILHLNALMKNKAKTRVLGH
SSAQRVPGDGRPLSPHPLTLENWVFSQYSSNSF
LKAVEPLYSKVHCRCSNSPFLFPLPPASFADSQ
LVMSVSIKDIMLLRF*RQVPAHG*LWLP*ENIFL
PKSVGNLNLSPLCRCLAASDIWLRTHGKKKILA
NVVSFVNQDSYLCCYRISALNVW*RFLCLNIGE
ISLLKS*S*LSIGHDETDFN**RAGELHVLWNLL
QDSQSLIHLHSQHSPKNLTYLMGSIFFFLNVHQ
SCLAPNL*IYS*TW*MHSDLRL*EFLTFFHYIG
T*IFSL*SFLKVINKDHN***T*YISSVCVCNIP
NTFFFFSTVCKVQQFNIFKGLFKSSLRTNLKLL
QCNPTQYQH*NFDISLMLSSILFLSAFCC*FQT
ASIFPFAFKIVTIFFMIATVLPQFIIIKGFYLI*
RIQSFFLSLLCSEYNLCVRVCCVCACVAYMCVT
G*CLLGIVLMFSWFIMPSEW*MRTLQL*SAHNF
*IKDTTVHAVCS

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