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Sequences

Sequence NM_198883

AAGCCCCAGCCCGGCCTCCGCTCCGGCCGCCGCCACCGCCCCTGTTTTGTTTCCATGGCGACAGGCGGCGCAGGGCCCGCTCCAAACATAACGCGCTGTG GAAAACATGCTGCTCGGGGGACCCCCCCGCAGTCCCCGCTCGGGGACGAGCCCCAAGGGGCCCTGGAGCAGTACAGGCCACGTGCAGTTTGGCAAGAGCC CCCAGACCTGGCCCAGGCGCACAAGACCCCGCTCTCCAGAGCCTGCCGCGCCTTCAGGGGTTCGGGGCTCCACTTGGACGAGGCGCCGTGACACTCCGAG GCGCGCCGGGCCGACAGCGCTGTCCCGCTACGTGGGCCACCTCTGGATGGGCCGGCGGCCGCCCTCCCCCGAGGCCCGCGGCCCAGTCCCCCGCAGTTCA GCTGCCAGTCGGGCCAGAAGAAGCCTCGCCTCCCCGGGGATCTCCCCAGGCCCCCTGACCGCAACGATCGGAGGGGCGGTGGCGGGGGGCGGGCCCAGGC AGGGGAGGGCAGAAGCACACAAGGAAGTGTTTCCGGGACAGAGGGTGGGCAAGATGGCGGCGCCCATGGAGCTGTTCTGCTGGTCAGGGGGCTGGGGGCT GCCGTCAGTGGACCTGGACAGCCTGGCCGTGCTGACCTATGCCAGATTTACTGGTGCTCCACTGAAGGTACACAAGATCAGCAACCCCTGGCAGAGCCCT TCAGGAACTCTGCCTGCCCTTCGGACCAGTCATGGAGAGGTCATCTCAGTTCCACACAAGATCATCACCCACCTTCGAAAAGAGGTACATACTTTTTGGA TAGACACCAAGAACTACGTGGAAGTGACCCGGAAGTGGTATGCAGAGGCTATGCCCTTTCCCCTCAACTTCTTCCTGCCTGGCCGCATGCAGCGGCAGTA CATGGAACGGCTACAGCTGCTGACTGGGGAGCACAGGCCTGAGGACGAGGAAGAGCTGGAGAAGGAGCTGTACCGAGAGGCTCGGGAGTGTCTGACCCTG CTCTCTCAGCGCCTGGGCTCTCAAAAGTTCTTCTTTGGAGATGCCCCTGCCTCCTTGGACGCCTTCGTCTTCAGCTACTTGGCCCTGCTGCTGCAGGCAA AGCTGCCCAGTGGGAAGCTGCAGGTCCACCTGCGTGGGCTGCACAACCTCTGTGCCTATTGTACCCACATTCTCAGTCTCTACTTCCCCTGGGATGGAGC TGAGGTACCACCGCAACGCCAGACACCAGCAGGCCCAGAGACTGAGGAGGAGCCATACCGGCGCCGGAACCAGATCCTATCTGTGCTGGCAGGACTGGCA GCCATGGTGGGCTACGCCTTGCTCAGCGGCATTGTCTCCATCCAGCGGGCAACGCCTGCTCGGGCCCCAGGCACCCGGACCCTGGGCATGGCTGAGGAGG ATGAAGAGGAATGATTTGTCCTCACGCTCCCAAGACTGGTTTTTCTACTCTCATGCATTCCAGAGGCCCCCGTGCCTCCTCGTTGTTGGTACAGCCGGAC ACGGGGTGCTGCCACCCAGAATAAAGCCACTCACACTGACTGGGCTCAAA

refseq_MTX1.F1 (forward primer)
refseq_MTX1.R1 (reverse primer)
Single exon skipping

Frame 0

KPQPGLRSGRRHRPCFVSMATGGAGPAPNITRC GKHAARGTPPQSPLGDEPQGALEQYRPRAVWQEP PDLAQAHKTPLSRACRAFRGSGLHLDEAP*HSE ARRADSAVPLRGPPLDGPAAALPRGPRPSPPQF SCQSGQKKPRLPGDLPRPPDRNDRRGGGGGRAQA GEGRSTQGSVSGTEGGQDGGAHGAVLLVRGLGA AVSGPGQPGRADLCQIYWCSTEGTQDQQPLAEP FRNSACPSDQSWRGHLSSTQDHHPPSKRGTYFLD RHQELRGSDPEVVCRGYALSPQLLPAWPHAAAV HGTATAADWGAQA*GRGRAGEGAVPRGSGVSDP ALSAPGLSKVLLWRCPCLLGRLRLQLLGPAAAGK AAQWEAAGPPAWAAQPLCLLYPHSQSLLPLGWS *GTTATPDTSRPRD*GGAIPAPEPDPICAGRTG SHGGLRLAQRHCLHPAGNACSGPRHPDPGHG*GG *RGMICPHAPKTGFSTLMHSRGPRASSLLVQPD TGCCHPE*SHSH*LGS

Frame 1

SPSPASAPAAATAPVLFPWRQAAQGPLQT*RAV ENMLLGGPPRSPRSGTSPKGPWSSTGHVQFGKS PQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDTPR RAGPTALSRYVGHLWMGRRPPSPEARGPVPRSS AASRARRSLASPGISPGPLTATIGGAVAGGGPR QGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGL PSVDLDSLAVLTYARFTGAPLKVHKISNPWQSP SGTLPALRTSHGEVISVPHKIITHLRKEVHTFW IDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQY MERLQLLTGEHRPEDEEELEKELYREARECLTL LSQRLGSQKFFFGDAPASLDAFVFSYLALLLQA KLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGA EVPPQRQTPAGPETEEEPYRRRNQILSVLAGLA AMVGYALLSGIVSIQRATPARAPGTRTLGMAEE DEEE*FVLTLPRLVFLLSCIPEAPVPPRCWYSRT RGAATQNKATHTDWAQ

Frame 2

APARPPLRPPPPPLFCFHGDRRRRARSKHNALW KTCCSGDPPAVPARGRAPRGPGAVQATCSLARA PRPGPGAQDPALQSLPRLQGFGAPLGRGAVTLR GAPGRQRCPATWATSGWAGGRPPPRPAAQSPAVQ LPVGPEEASPPRGSPQAP*PQRSEGRWRGAGPG RGGQKHTRKCFRDRGWARWRRPWSCSAGQGAGG CRQWTWTAWPC*PMPDLLVLH*RYTRSATPGRAL QELCLPFGPVMERSSQFHTRSSPTFEKRYILFG *TPRTTWK*PGSGMQRLCPFPSTSSCLAACSGS TWNGYSC*LGSTGLRTRKSWRRSCTERLGSV*PC SLSAWALKSSSLEMPLPPWTPSSSATWPCCCRQ SCPVGSCRSTCVGCTTSVPIVPTFSVSTSPGME LRYHRNARHQQAQRLRRSHTGAGTRSYLCWQDWQ PWWATPCSAALSPSSGQRLLGPQAPGPWAWLRR MKRNDLSSRSQDWFFYSHAFQRPPCLLVVGTAG HGVLPPRIKPLTLTGLK

Sequence NM_002455

AAGCCCCAGCCCGGCCTCCGCTCCGGCCGCCGCCACCGCCCCTGTTTTGTTTCCATGGCGACAGGCGGCGCAGGGCCCGCTCCAAACATAACGCGCTGTG GAAAACATGCTGCTCGGGGGACCCCCCCGCAGTCCCCGCTCGGGGACGAGCCCCAAGGGGCCCTGGAGCAGTACAGGCCACGTGCAGTTTGGCAAGAGCC CCCAGACCTGGCCCAGGCGCACAAGACCCCGCTCTCCAGAGCCTGCCGCGCCTTCAGGGGTTCGGGGCTCCACTTGGACGAGGCGCCGTGACACTCCGAG GCGCGCCGGGCCGACAGCGCTGTCCCGCTACGTGGGCCACCTCTGGATGGGCCGGCGGCCGCCCTCCCCCGAGGCCCGCGGCCCAGTCCCCCGCAGTTCA GCTGCCAGTCGGGCCAGAAGAAGCCTCGCCTCCCCGGGGATCTCCCCAGGCCCCCTGACCGCAACGATCGGAGGGGCGGTGGCGGGGGGCGGGCCCAGGC AGGGGAGGGCAGAAGCACACAAGGAAGTGTTTCCGGGACAGAGGGTGGGCAAGATGGCGGCGCCCATGGAGCTGTTCTGCTGGTCAGGGGGCTGGGGGCT GCCGTCAGTGGACCTGGACAGCCTGGCCGTGCTGACCTATGCCAGATTTACTGGTGCTCCACTGAAGGTACACAAGATCAGCAACCCCTGGCAGAGCCCT TCAGGAACTCTGCCTGCCCTTCGGACCAGTCATGGAGAGGTCATCTCAGTTCCACACAAGATCATCACCCACCTTCGAAAAGAGAAGTACAATGCTGATT ATGATCTGTCAGCTCGGCAAGGGGCAGACACCCTGGCCTTCATGTCTCTCCTGGAGGAGAAGTTGCTCCCGGTGCTGGTACATACTTTTTGGATAGACAC CAAGAACTACGTGGAAGTGACCCGGAAGTGGTATGCAGAGGCTATGCCCTTTCCCCTCAACTTCTTCCTGCCTGGCCGCATGCAGCGGCAGTACATGGAA CGGCTACAGCTGCTGACTGGGGAGCACAGGCCTGAGGACGAGGAAGAGCTGGAGAAGGAGCTGTACCGAGAGGCTCGGGAGTGTCTGACCCTGCTCTCTC AGCGCCTGGGCTCTCAAAAGTTCTTCTTTGGAGATGCCCCTGCCTCCTTGGACGCCTTCGTCTTCAGCTACTTGGCCCTGCTGCTGCAGGCAAAGCTGCC CAGTGGGAAGCTGCAGGTCCACCTGCGTGGGCTGCACAACCTCTGTGCCTATTGTACCCACATTCTCAGTCTCTACTTCCCCTGGGATGGAGCTGAGGTA CCACCGCAACGCCAGACACCAGCAGGCCCAGAGACTGAGGAGGAGCCATACCGGCGCCGGAACCAGATCCTATCTGTGCTGGCAGGACTGGCAGCCATGG TGGGCTACGCCTTGCTCAGCGGCATTGTCTCCATCCAGCGGGCAACGCCTGCTCGGGCCCCAGGCACCCGGACCCTGGGCATGGCTGAGGAGGATGAAGA GGAATGATTTGTCCTCACGCTCCCAAGACTGGTTTTTCTACTCTCATGCATTCCAGAGGCCCCCGTGCCTCCTCGTTGTTGGTACAGCCGGACACGGGGT GCTGCCACCCAGAATAAAGCCACTCACACTGACTGGGCTCAAA

refseq_MTX1.F1 (forward primer)
refseq_MTX1.R1 (reverse primer)
Single exon skipping

Frame 0

KPQPGLRSGRRHRPCFVSMATGGAGPAPNITRC GKHAARGTPPQSPLGDEPQGALEQYRPRAVWQEP PDLAQAHKTPLSRACRAFRGSGLHLDEAP*HSE ARRADSAVPLRGPPLDGPAAALPRGPRPSPPQF SCQSGQKKPRLPGDLPRPPDRNDRRGGGGGRAQA GEGRSTQGSVSGTEGGQDGGAHGAVLLVRGLGA AVSGPGQPGRADLCQIYWCSTEGTQDQQPLAEP FRNSACPSDQSWRGHLSSTQDHHPPSKREVQC*L *SVSSARGRHPGLHVSPGGEVAPGAGTYFLDRH QELRGSDPEVVCRGYALSPQLLPAWPHAAAVHG TATAADWGAQA*GRGRAGEGAVPRGSGVSDPALS APGLSKVLLWRCPCLLGRLRLQLLGPAAAGKAA QWEAAGPPAWAAQPLCLLYPHSQSLLPLGWS*G TTATPDTSRPRD*GGAIPAPEPDPICAGRTGSHG GLRLAQRHCLHPAGNACSGPRHPDPGHG*GG*R GMICPHAPKTGFSTLMHSRGPRASSLLVQPDTG CCHPE*SHSH*LGS

Frame 1

SPSPASAPAAATAPVLFPWRQAAQGPLQT*RAV ENMLLGGPPRSPRSGTSPKGPWSSTGHVQFGKS PQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDTPR RAGPTALSRYVGHLWMGRRPPSPEARGPVPRSS AASRARRSLASPGISPGPLTATIGGAVAGGGPR QGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGL PSVDLDSLAVLTYARFTGAPLKVHKISNPWQSP SGTLPALRTSHGEVISVPHKIITHLRKEKYNAD YDLSARQGADTLAFMSLLEEKLLPVLVHTFWIDT KNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYME RLQLLTGEHRPEDEEELEKELYREARECLTLLS QRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLP SGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEV PPQRQTPAGPETEEEPYRRRNQILSVLAGLAAM VGYALLSGIVSIQRATPARAPGTRTLGMAEEDEE E*FVLTLPRLVFLLSCIPEAPVPPRCWYSRTRG AATQNKATHTDWAQ

Frame 2

APARPPLRPPPPPLFCFHGDRRRRARSKHNALW KTCCSGDPPAVPARGRAPRGPGAVQATCSLARA PRPGPGAQDPALQSLPRLQGFGAPLGRGAVTLR GAPGRQRCPATWATSGWAGGRPPPRPAAQSPAVQ LPVGPEEASPPRGSPQAP*PQRSEGRWRGAGPG RGGQKHTRKCFRDRGWARWRRPWSCSAGQGAGG CRQWTWTAWPC*PMPDLLVLH*RYTRSATPGRAL QELCLPFGPVMERSSQFHTRSSPTFEKRSTMLI MICQLGKGQTPWPSCLSWRRSCSRCWYILFG*T PRTTWK*PGSGMQRLCPFPSTSSCLAACSGSTWN GYSC*LGSTGLRTRKSWRRSCTERLGSV*PCSL SAWALKSSSLEMPLPPWTPSSSATWPCCCRQSC PVGSCRSTCVGCTTSVPIVPTFSVSTSPGMELRY HRNARHQQAQRLRRSHTGAGTRSYLCWQDWQPW WATPCSAALSPSSGQRLLGPQAPGPWAWLRRMK RNDLSSRSQDWFFYSHAFQRPPCLLVVGTAGHGV LPPRIKPLTLTGLK