Sequences - Rnomics 📊 Palace

        ☰
    
        Rnomics 📊 Palace
    
                       Back to Rnomics Platform
            
                       Open Session

1 warning:

Access restricted to public data.
Please sign in at Rnomics Platform to access your data.

Navigation

Home

Sequences

Sequence NM_001001924

CGTGGGCCAGCGCAGAGCCTGCGGAAGGGACGGATGCGGATCTCGTCGCTGTCACCTTGAAAGTGACCGAGGGGCTTGACTGTGGACTCCTTACGCCGCC CACCCGGGCCCGGCGGTCCCAGCCTTCTCGCAGGGCCCCTTCTCAGCAGAAGCAAGCGGGGCCGAGAAAGCGGGTGGAATAGGGTTGCTGCAGGTCCCAA AGACCCCTCGTGGCGCCTCGCTACTTTCTGCAGCTTGTTTGCACTTTTTCACGCTCTAGAAAAATCTCATCTTAATTAAGGGAACAACAAATCATTTAAT CTTCAGAGCATCTTAGACTGAAAACCTTTCAACTGTGCTGAAAAACCTAGAAGACAGACCATTTTGCCCACCCTCTCATTTAAAAGGAATTGAAGAAGAA ATAAAATGGCAGAGGTTTAAGGTTACTATTCAGGATGACTGATGATAATTCAGATGATAAAATAGAAGATGAATTGCAAACCTTCTTTACCAGTGATAAA GATGGAAATACACATGCATACAACCCGAAATCACCACCTACACAAAACTCTTCAGCCAGCAGTGTGAACTGGAATTCTGCCAACCCAGATGACATGGTGG TTGATTATGAAACTGACCCTGCTGTAGTTACTGGTGAAAATATTTCTTTAAGCCTTCAGGGTGTTGAAGTATTTGGTCATGAAAAGTCTTCTAGTGATTT CATTAGTAAGCAGGTGTTAGATATGCATAAAGATTCTATTTGTCAGTGTCCTGCACTTGTAGGTACTGAGAAGCCCAAATATCTGCAACACAGTTGTCAT TCCCTAGAAGCAGTTGAGGGCCAGAGTGTTGAGCCATCTTTGCCTTTTGTGTGGAAGCCTAATGACAATTTGAACTGTGCAGGCTACTGTGATGCCTTGG AGCTAAACCAAACATTTGACATGACAGTGGATAAAGTTAACTGCACCTTTATATCACATCATGCCATCGGAAAGAGTCAGTCCTTCCATACTGCTGGAAG CCTGCCACCAACTGGTAGGAGAAGTGGAAGTACATCTTCTTTATCCTATTCCACTTGGACATCTTCCCATTCTGATAAGACGCATGCAAGAGAAACTACT TATGATAGAGAAAGCTTTGAAAACCCTCAAGTCACACCATCAGAAGCCCAAGACATGACTTACACAGCATTTTCTGATGTGGTGATGCAAAGTGAGGTTT TTGTTTCAGATATTGGAAATCAGTGTGCATGTTCTTCAGGAAAGGTCACCAGTGAGTACACAGATGGATCACAACAAAGACTAGTTGGAGAAAAGGAGAC ACAAGCACTAACACCAGTTTCTGATGGCATGGAAGTCCCCAATGATTCTGCATTACAAGAGTTCTTTTGTTTATCCCATGATGAATCCAATAGCGAACCA CATTCACAGAGCTCATACAGGCACAAGGAAATGGGCCAAAATCTGAGAGAGACAGTGTCCTATTGTCTTATTGATGATGAATGCCCTTTAATGGTGCCAG CTTTTGATAAGAGCGAAGCTCAAGTGCTGAACCCAGAGCATAAAGTCACTGAGACTGAAGACACACAAATGGTCTCCAAAGGAAAGGATTTGGGAACCCA AAATCATACCTCAGAATTGATTCTAAGTAGCCCGCCAGGACAAAAGGTGGGCTCGTCATTTGGACTGACTTGGGATGCAAATGATATGGTCATTAGCACA GACAAAACGATGTGCATGTCAACACCAGTCCTAGAACCCACAAAAGTAACCTTTTCTGTTTCACCGATTGAAGCGACGGAGAAATGTAAGAAAGTGGAGA AGGGTAATCGAGGGCTTAAAAACATACCAGACTCGAAGGAGGCACCTGTGAACCTGTGTAAACCCAGTTTAGGAAAATCAACAATCAAAACGAATACCCC AATAGGCTGCAAAGTTAGAAAAACTGAAATTATAAGTTACCCAAGACCAAACTTCAAGAATGTCAAAGCAAAAGTTATGTCTAGAGCAGTGTTGCAGCCC AAAGATGCTGCTTTATCAAAGGTCACGCCCAGACCTCAGCAGACCAGTGCCTCATCACCCTCATCAGTGAATTCAAGACAACAAACAGTCTTGAGCAGAA CACCGAGATCTGACTTGAATGCAGACAAAAAAGCAGAAATTCTAATTAACAAGACACATAAGCAGCAGTTTAATAAACTCATTACTAGCCAGGCTGTGCA TGTTACAACTCATTCTAAAAATGCTTCACACAGGGTTCCAAGAACAACATCTGCCGTGAAATCGAATCAGGAAGATGTTGACAAAGCCAGTTCTTCTAAC TCAGCATGCGAGACCGGGTCCGTTTCTGCGTTGTTTCAGAAGATCAAAGGCATACTCCCTGTTAAAATGGAAAGTGCAGAATGTTTGGAAATGACCTATG TTCCCAACATTGATAGGATTAGCCCTGAAAAGAAGGGTGAAAAAGAAAATGGGACATCTATGGAAAAACAAGAGCTGAAACAAGAGATTATGAATGAGAC TTTTGAATATGGTTCTCTGTTTTTGGGCTCTGCTTCAAAAACAACGACCACCTCAGGTAGGAATATATCCAAGCCTGACTCCTGCGGTTTGAGGCAAATA GCTGCTCCAAAAGCCAAAGTGGGGCCCCCTGTTTCCTGTTTGAGGCGGAACAGTGACAATAGAAATCCCAGTGCTGATCGAGCCGTATCTCCTCAGAGGA TCAGGCGTGTGTCCAGTTCTGGAAAGCCTACATCCTTGAAAACTGCACAGTCGTCATGGGTGAATTTGCCTAGACCACTTCCTAAATCCAAAGCATCTTT GAAAAGTCCTGCGCTGCGGAGGACAGGAAGCACCCCCTCAATAGCCAGCACCCACAGTGAGCTGAGCACTTACAGCAACAATTCTGGTAATGCCGCTGTC ATCAAATATGAGGAGAAACCTCCAAAACCAGCATTTCAGAATGGTTCCTCAGGATCCTTTTATTTGAAGCCTTTGGTATCCAGGGCTCATGTTCACTTGA TGAAAACTCCTCCAAAAGGTCCTTCGAGAAAAAATTTATTTACAGCTCTTAATGCAGTTGAAAAGAGCAGGCAAAAGAATCCTCGAAGCTTATGTATCCA GCCACAGACAGCTCCCGATGCGCTGCCCCCTGAGAAAACACTTGAATTGACGCAATATAAAACAAAATGTGAAAACCAAAGTGGATTTATCCTGCAGCTC AAGCAGCTTCTTGCCTGTGGTAATACCAAGTTTGAGGCATTGACAGTTGTGATTCAGCACCTGCTGTCTGAGCGGGAGGAAGCACTGAAACAACACAAAA CCCTATCTCAAGAACTTGTTAACCTCCGGGGAGAGCTAGTCACTGCTTCAACCACCTGTGAGAAATTAGAAAAAGCCAGGAATGAGTTACAAACAGTGTA TGAAGCATTCGTCCAGCAGCACCAGGCTGAAAAAACAGAACGAGAGAATCGGCTTAAAGAGTTTTACACCAGGGAGTATGAAAAGCTTCGGGACACTTAC ATTGAAGAAGCAGAGAAGTACAAAATGCAATTGCAAGAGCAGTTTGACAACTTAAATGCTGCGCATGAAACCTCTAAGTTGGAAATTGAAGCTAGCCACT CAGAGAAACTTGAATTGCTAAAGAAGGCCTATGAAGCCTCCCTTTCAGAAATTAAGAAAGGCCATGAAATAGAAAAGAAATCGCTTGAAGATTTACTTTC TGAGAAGCAGGAATCGCTAGAGAAGCAAATCAATGATCTGAAGAGTGAAAATGATGCTTTAAATGAAAAATTGAAATCAGAAGAACAAAAAAGAAGAGCA AGAGAAAAAGCAAATTTGAAAAATCCTCAGATCATGTATCTAGAACAGGAGTTAGAAAGCCTGAAAGCTGTGTTAGAGATCAAGAATGAGAAACTGCATC AACAGGACATCAAGTTAATGAAAATGGAGAAACTGGTGGACAACAACACAGCATTGGTTGACAAATTGAAGCGTTTCCAGCAGGAGAATGAAGAATTGAA AGCTCGGATGGACAAGCACATGGCAATCTCAAGGCAGCTTTCCACGGAGCAGGCTGTTCTGCAAGAGTCGCTGGAGAAGGAGTCGAAAGTCAACAAGCGA CTCTCTATGGAAAACGAGGAGCTTCTGTGGAAACTGCACAATGGGGACCTGTGTAGCCCCAAGAGATCCCCCACATCCTCCGCCATCCCTTTGCAGTCAC CAAGGAATTCGGGCTCCTTCCCTAGCCCCAGCATTTCACCCAGATGACACCTCCCCAAAGTCCACAGACTCTCTGAAAGCATTTTGATGCAGGTCTGCAG GACTGACCCCAAGGAGGAACGTGGGCACAAGAGGTATATCAGCACACGTGTGATCACCGTAGGGTAACTGGAGCGTCACCACCGGCGGAATCGCAGCTTC TGAGACTGGAACTCTGGAGGAAGACTTTTGCCTCCGTCCAAAAGATTCCTCCAAAAAAAGATTTAAAAAAAGATTTCGGCATCGACACGGACGTTGTTGC ACAAAGCACTTAAAGAACGAGAGCATCTTGTTCATTGCCTTTTTCACCTAAGCATAGGGGGAAAAACTCTCAGGGCCCTATTAAGATTTATAACCTTTGT AATGTTCTTCACCACAGACACCTTCTTGTGAGTTTTCAGTCTGACTGTGGGGGTGGGGGGTGTGAATGAAATGGATGTCACAGAGTGTCATGTGTCTGAT GCAGCCTCCTCTGCTGTGTATTAAATGTCAAAATCTGAATATATCTGGATATGTACTAATCAAATAATAATCAATCAATCAGCATATACATTTCAGCCAA AGCCATAGAAGAAAAAGCAATAGTTGCTTGAATTATGATCATCTACCACCAACTCTGCTCAGCCCTGTAACAGGGTAGGGAGAGGGTATAACAGGAAGAG CTTTGACTTGTCCCTGTCTATACATTCTCTGTATCTTTTGGGGGTAACTTCTTGGCAGTTTTTCAGTGTTCAGCCATGTCAGTTGAAACTAGATTTTTCT GTAGATTTTTTACTTACCCATGTGAGCCTAACACTATCCTGTAATTCATTTTCTCAGGCTATGTGTAAATGTAGAACCCTAATTTTTCTATAAAAAAACA AACTAACTAACTAACTGTGTAAAGAAAGAAAAAGGGAAGTACCAATGGGTTTTTCCACCTTATTTTTACCTTTGATCTACCCTTGCAGATTTAACCTGTC TTCTTCCCTCCCATTATTCTCATTTTCCTTTTACCTTTCTCCACCATCCAGAGCCACAAAAGCAAACCTTCTACCTCCTACCTACTTTTCTCTGGGACAA GGATAAAGGAATATGATTTTCCAGAGCCCCAGAGCCAGCTCATCTTCCAGGTGCTGAAACCACTTTCCAAATAAACTAAAGCCTGGATTTGATATTACAA ATTTTGGGAAATCTTAGAATAAAGAACGAGAACAAGGAAGTCATTGGCTAGTATAATTAAGAAAGGTAGGATTCAGTGCTTACCGATGATGCAGTACTTG ATAGAAGAAAACAGTCTGGGAGGATAGCGCTCATTTTTCAGTTACCCTTTAAGGAGTCCCTTTGTCTTTGGGAAAGTAGCAGAATGGTCCGCTTCTTTCC CATGAGTGGAAAATGTGGCTTGTCCAACTCTCCTCCAGGTTGCATTTCAGTTTCTTTCCAAAACTTATTACCTCCCCTAATCCTGAGACTTTGGAAAAGG TGGAAGGAAGAACTGTTGCTTTATCTCCCCCTCCCTGCATGTGTCAACATTGTGATGTCAGTATTTACTAATCTACATTCAGTGGCTGTACAAATAACAG CTGTAGTAAGAAGAGATTCAGGATGCTAGAGGTGAATATTTGGGTCATTTACATGTACACTACATAGCAAGTTGATACTCATGTTGCATGTTCTTTTAAA TTAGTGATTTTGTGTCTTAAGTCTTTAACTTCCAATACTTCATCATGTATGTAACCTTCCATGTTTGCTTCTGATAAATGGAAATGTAGGTTCACTGCCA CTTCATGAGATATCTCTGCTCACGCTTCCAAGTTGTTCTCAATGACATTAGCCAAAGTTGGGTTTGCCATTCATCCCCTAGGCATGGTAAATCTTGTGTT GTTCCCTGCTGTCCTCCGTATTACGTGACCGGCAAATAAATCTCATAGCAGTTAATATAAAACATCTTTGGAGGATGGGAGAGAACAGGAGGGAAGATGG GAAACAAAATAGAGAATTCTTAAGATTTTGTTTAAACCAAATGTTTCATGTAGAATGCAAAATGTTGGCACGTCAAAAATATGAATGTGTAGACAACTGT AGTTGTGCTCAGTTTGTAGTGATGGGAAGTGTATTTTACTCTGATCAAATAAATAATGCTGGAATACTCAAGAATTGCA

refseq_MTUS1.F2 (forward primer)
refseq_MTUS1.R2 (reverse primer)
Single exon skipping

Frame 0

RGPAQSLRKGRMRISSLSP*K*PRGLTVDSLRR PPGPGGPSLLAGPLLSRSKRGRESGWNRVAAGPK DPSWRLATFCSLFALFHALEKSHLN*GNNKSFN LQSILD*KPFNCAEKPRRQTILPTLSFKRN*RR NKMAEV*GYYSG*LMIIQMIK*KMNCKPSLPVIK MEIHMHTTRNHHLHKTLQPAV*TGILPTQMTWW LIMKLTLL*LLVKIFL*AFRVLKYLVMKSLLVI SLVSRC*ICIKILFVSVLHL*VLRSPNICNTVVI P*KQLRARVLSHLCLLCGSLMTI*TVQATVMPW S*TKHLT*QWIKLTAPLYHIMPSERVSPSILLE ACHQLVGEVEVHLLYPIPLGHLPILIRRMQEKLL MIEKALKTLKSHHQKPKT*LTQHFLMW*CKVRF LFQILEISVHVLQERSPVSTQMDHNKD*LEKRR HKH*HQFLMAWKSPMILHYKSSFVYPMMNPIANH IHRAHTGTRKWAKI*ERQCPIVLLMMNAL*WCQ LLIRAKLKC*TQSIKSLRLKTHKWSPKERIWEP KIIPQN*F*VARQDKRWARHLD*LGMQMIWSLAQ TKRCACQHQS*NPQK*PFLFHRLKRRRNVRKWR RVIEGLKTYQTRRRHL*TCVNPV*ENQQSKRIP Q*AAKLEKLKL*VTQDQTSRMSKQKLCLEQCCSP KMLLYQRSRPDLSRPVPHHPHQ*IQDNKQS*AE HRDLT*MQTKKQKF*LTRHISSSLINSLLARLC MLQLILKMLHTGFQEQHLP*NRIRKMLTKPVLLT QHARPGPFLRCFRRSKAYSLLKWKVQNVWK*PM FPTLIGLALKRRVKKKMGHLWKNKS*NKRL*MR LLNMVLCFWALLQKQRPPQVGIYPSLTPAV*GK* LLQKPKWGPLFPV*GGTVTIEIPVLIEPYLLRG SGVCPVLESLHP*KLHSRHG*ICLDHFLNPKHL *KVLRCGGQEAPPQ*PAPTVS*ALTATILVMPLS SNMRRNLQNQHFRMVPQDPFI*SLWYPGLMFT* *KLLQKVLREKIYLQLLMQLKRAGKRILEAYVS SHRQLPMRCPLRKHLN*RNIKQNVKTKVDLSCSS SSFLPVVIPSLRH*QL*FSTCCLSGRKH*NNTK PYLKNLLTSGES*SLLQPPVRN*KKPGMSYKQC MKHSSSSTRLKKQNERIGLKSFTPGSMKSFGTLT LKKQRSTKCNCKSSLTT*MLRMKPLSWKLKLAT QRNLNC*RRPMKPPFQKLRKAMK*KRNRLKIYF LRSRNR*RSKSMI*RVKMML*MKN*NQKNKKEEQ EKKQI*KILRSCI*NRS*KA*KLC*RSRMRNCI NRTSS**KWRNWWTTTQHWLTN*SVSSRRMKN* KLGWTSTWQSQGSFPRSRLFCKSRWRRSRKSTSD SLWKTRSFCGNCTMGTCVAPRDPPHPPPSLCSH QGIRAPSLAPAFHPDDTSPKSTDSLKAF*CRSA GLTPRRNVGTRGISAHV*SP*GNWSVTTGGIAAS ETGTLEEDFCLRPKDSSKKRFKKRFRHRHGRCC TKHLKNESILFIAFFT*A*GEKLSGPY*DL*PL *CSSPQTPSCEFSV*LWGWGV*MKWMSQSVMCLM QPPLLCIKCQNLNISGYVLIK**SINQHIHFSQ SHRRKSNSCLNYDHLPPTLLSPVTG*GEGITGR ALTCPCLYILCIFWG*LLGSFSVFSHVS*N*IFL *IFYLPM*A*HYPVIHFLRLCVNVEP*FFYKKT N*LTNCVKKEKGKYQWVFPPYFYL*STLADLTC LLPSHYSHFPFTFLHHPEPQKQTFYLLPTFLWDK DKGI*FSRAPEPAHLPGAETTFQIN*SLDLILQ ILGNLRIKNENKEVIG*YN*ER*DSVLTDDAVL DRRKQSGRIALIFQLPFKESLCLWESSRMVRFFP MSGKCGLSNSPPGCISVSFQNLLPPLILRLWKR WKEELLLYLPLPACVNIVMSVFTNLHSVAVQIT AVVRRDSGC*R*IFGSFTCTLHSKLILMLHVLLN **FCVLSL*LPILHHVCNLPCLLLINGNVGSLP LHEISLLTLPSCSQ*H*PKLGLPFIP*AW*ILC CSLLSSVLRDRQINLIAVNIKHLWRMGENRREDG KQNREFLRFCLNQMFHVECKMLARQKYECVDNC SCAQFVVMGSVFYSDQINNAGILKNC

Frame 1

VGQRRACGRDGCGSRRCHLESDRGA*LWTPYAA HPGPAVPAFSQGPFSAEASGAEKAGGIGLLQVP KTPRGASLLSAACLHFFTL*KNLILIKGTTNHLI FRAS*TENLSTVLKNLEDRPFCPPSHLKGIEEE IKWQRFKVTIQDD***FR**NRR*IANLLYQ** RWKYTCIQPEITTYTKLFSQQCELEFCQPR*HGG *L*N*PCCSYW*KYFFKPSGC*SIWS*KVF**F H**AGVRYA*RFYLSVSCTCRY*EAQISATQLS FPRSS*GPEC*AIFAFCVEA**QFELCRLL*CLG AKPNI*HDSG*S*LHLYITSCHRKESVLPYCWK PATNW*EKWKYIFFILFHLDIFPF**DACKRNY L**RKL*KPSSHTIRSPRHDLHSIF*CGDAK*GF CFRYWKSVCMFFRKGHQ*VHRWITTKTSWRKGD TSTNTSF*WHGSPQ*FCITRVLLFIP**IQ*RT TFTELIQAQGNGPKSERDSVLLSY***MPFNGAS F**ERSSSAEPRA*SH*D*RHTNGLQRKGFGNP KSYLRIDSK*PARTKGGLVIWTDLGCK*YGH*H RQNDVHVNTSPRTHKSNLFCFTD*SDGEM*ESGE G*SRA*KHTRLEGGTCEPV*TQFRKINNQNEYP NRLQS*KN*NYKLPKTKLQECQSKSYV*SSVAA QRCCFIKGHAQTSADQCLITLISEFKTTNSLEQN TEI*LECRQKSRNSN*QDT*AAV**THY*PGCA CYNSF*KCFTQGSKNNICREIESGRC*QSQFF* LSMRDRVRFCVVSEDQRHTPC*NGKCRMFGNDLC SQH**D*P*KEG*KRKWDIYGKTRAETRDYE*D F*IWFSVFGLCFKNNDHLR*EYIQA*LLRFEAN SCSKSQSGAPCFLFEAEQ*Q*KSQC*SSRISSED QACVQFWKAYILENCTVVMGEFA*TTS*IQSIF EKSCAAEDRKHPLNSQHPQ*AEHLQQQFW*CRC HQI*GETSKTSISEWFLRILLFEAFGIQGSCSLD ENSSKRSFEKKFIYSS*CS*KEQAKESSKLMYP ATDSSRCAAP*ENT*IDAI*NKM*KPKWIYPAA QAASCLW*YQV*GIDSCDSAPAV*AGGSTETTQN PISRTC*PPGRASHCFNHL*EIRKSQE*VTNSV *SIRPAAPG*KNRTRESA*RVLHQGV*KASGHL H*RSREVQNAIARAV*QLKCCA*NL*VGN*S*PL RET*IAKEGL*SLPFRN*ERP*NRKEIA*RFTF *EAGIAREANQ*SEE*K*CFK*KIEIRRTKKKS KRKSKFEKSSDHVSRTGVRKPESCVRDQE*ETAS TGHQVNENGETGGQQHSIG*QIEAFPAGE*RIE SSDGQAHGNLKAAFHGAGCSARVAGEGVESQQA TLYGKRGASVETAQWGPV*PQEIPHILRHPFAVT KEFGLLP*PQHFTQMTPPQSPQTL*KHFDAGLQ D*PQGGTWAQEVYQHTCDHRRVTGASPPAESQL LRLELWRKTFASVQKIPPKKDLKKDFGIDTDVVA QST*RTRASCSLPFSPKHRGKNSQGPIKIYNLC NVLHHRHLLVSFQSDCGGGGCE*NGCHRVSCV* CSLLCCVLNVKI*IYLDMY*SNNNQSISIYISAK AIEEKAIVA*IMIIYHQLCSAL*QGRERV*QEE L*LVPVYTFSVSFGGNFLAVFQCSAMSVETRFF CRFFTYPCEPNTIL*FIFSGYV*M*NPNFSIKKQ TN*LTV*RKKKGSTNGFFHLIFTFDLPLQI*PV FFPPIILIFLLPFSTIQSHKSKPSTSYLLFSGT RIKEYDFPEPQSQLIFQVLKPLSK*TKAWI*YYK FWEILE*RTRTRKSLASIIKKGRIQCLPMMQYL IEENSLGG*RSFFSYPLRSPFVFGKVAEWSASF P*VENVACPTLLQVAFQFLSKTYYLP*S*DFGKG GRKNCCFISPSLHVSTL*CQYLLIYIQWLYK*Q L**EEIQDARGEYLGHLHVHYIAS*YSCCMFF* ISDFVS*VFNFQYFIMYVTFHVCF**MEM*VHCH FMRYLCSRFQVVLNDISQSWVCHSSPRHGKSCV VPCCPPYYVTGK*IS*QLI*NIFGGWERTGGKM GNKIENS*DFV*TKCFM*NAKCWHVKNMNV*TTV VVLSL**WEVYFTLIK*IMLEYSRIA

Frame 2

WASAEPAEGTDADLVAVTLKVTEGLDCGLLTPP TRARRSQPSRRAPSQQKQAGPRKRVE*GCCRSQ RPLVAPRYFLQLVCTFSRSRKISS*LREQQII* SSEHLRLKTFQLC*KT*KTDHFAHPLI*KELKKK *NGRGLRLLFRMTDDNSDDKIEDELQTFFTSDK DGNTHAYNPKSPPTQNSSASSVNWNSANPDDMV VDYETDPAVVTGENISLSLQGVEVFGHEKSSSDF ISKQVLDMHKDSICQCPALVGTEKPKYLQHSCH SLEAVEGQSVEPSLPFVWKPNDNLNCAGYCDAL ELNQTFDMTVDKVNCTFISHHAIGKSQSFHTAGS LPPTGRRSGSTSSLSYSTWTSSHSDKTHARETT YDRESFENPQVTPSEAQDMTYTAFSDVVMQSEV FVSDIGNQCACSSGKVTSEYTDGSQQRLVGEKET QALTPVSDGMEVPNDSALQEFFCLSHDESNSEP HSQSSYRHKEMGQNLRETVSYCLIDDECPLMVP AFDKSEAQVLNPEHKVTETEDTQMVSKGKDLGTQ NHTSELILSSPPGQKVGSSFGLTWDANDMVIST DKTMCMSTPVLEPTKVTFSVSPIEATEKCKKVE KGNRGLKNIPDSKEAPVNLCKPSLGKSTIKTNTP IGCKVRKTEIISYPRPNFKNVKAKVMSRAVLQP KDAALSKVTPRPQQTSASSPSSVNSRQQTVLSR TPRSDLNADKKAEILINKTHKQQFNKLITSQAVH VTTHSKNASHRVPRTTSAVKSNQEDVDKASSSN SACETGSVSALFQKIKGILPVKMESAECLEMTY VPNIDRISPEKKGEKENGTSMEKQELKQEIMNET FEYGSLFLGSASKTTTTSGRNISKPDSCGLRQI AAPKAKVGPPVSCLRRNSDNRNPSADRAVSPQR IRRVSSSGKPTSLKTAQSSWVNLPRPLPKSKASL KSPALRRTGSTPSIASTHSELSTYSNNSGNAAV IKYEEKPPKPAFQNGSSGSFYLKPLVSRAHVHL MKTPPKGPSRKNLFTALNAVEKSRQKNPRSLCIQ PQTAPDALPPEKTLELTQYKTKCENQSGFILQL KQLLACGNTKFEALTVVIQHLLSEREEALKQHK TLSQELVNLRGELVTASTTCEKLEKARNELQTVY EAFVQQHQAEKTERENRLKEFYTREYEKLRDTY IEEAEKYKMQLQEQFDNLNAAHETSKLEIEASH SEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLS EKQESLEKQINDLKSENDALNEKLKSEEQKRRA REKANLKNPQIMYLEQELESLKAVLEIKNEKLH QQDIKLMKMEKLVDNNTALVDKLKRFQQENEELK ARMDKHMAISRQLSTEQAVLQESLEKESKVNKR LSMENEELLWKLHNGDLCSPKRSPTSSAIPLQS PRNSGSFPSPSISPR*HLPKVHRLSESILMQVCR TDPKEERGHKRYISTRVITVG*LERHHRRNRSF *DWNSGGRLLPPSKRFLQKKI*KKISASTRTLL HKALKEREHLVHCLFHLSIGGKTLRALLRFITFV MFFTTDTFL*VFSLTVGVGGVNEMDVTECHVSD AASSAVY*MSKSEYIWICTNQIIINQSAYTFQP KP*KKKQ*LLEL*SSTTNSAQPCNRVGRGYNRKS FDLSLSIHSLYLLGVTSWQFFSVQPCQLKLDFS VDFLLTHVSLTLSCNSFSQAMCKCRTLIFL*KN KLTN*LCKERKREVPMGFSTLFLPLIYPCRFNLS SSLPLFSFSFYLSPPSRATKANLLPPTYFSLGQ G*RNMIFQSPRASSSSRC*NHFPNKLKPGFDIT NFGKS*NKEREQGSHWLV*LRKVGFSAYR*CST* *KKTVWEDSAHFSVTL*GVPLSLGK*QNGPLLS HEWKMWLVQLSSRLHFSFFPKLITSPNPETLEK VEGRTVALSPPPCMCQHCDVSIY*STFSGCTNNS CSKKRFRMLEVNIWVIYMYTT*QVDTHVACSFK LVILCLKSLTSNTSSCM*PSMFASDKWKCRFTA TS*DISAHASKLFSMTLAKVGFAIHPLGMVNLVL FPAVLRIT*PANKSHSS*YKTSLEDGREQEGRW ETK*RILKILFKPNVSCRMQNVGTSKI*MCRQL *LCSVCSDGKCILL*SNK*CWNTQEL

Sequence NM_001001927

CGTGGGCCAGCGCAGAGCCTGCGGAAGGGACGGATGCGGATCTCGTCGCTGTCACCTTGAAAGTGACCGAGGGGCTTGACTGTGGACTCCTTACGCCGCC CACCCGGGCCCGGCGGTCCCAGCCTTCTCGCAGGGCCCCTTCTCAGCAGAAGCAAGCGGGGCCGAGAAAGCGGGTGGAATAGGGTTGCTGCAGGTCCCAA AGACCCCTCGTGGCGCCTCGCTACTTTCTGCAGCTTGTTTGCACTTTTTCACGCTCTAGAAAAATCTCATCTTAATTAAGGGAACAACAAATCATTTAAT CTTCAGAGCATCTTAGACTGAAAACCTTTCAACTGTGCTGAAAAACCTAGAAGACAGACCATTTTGCCCACCCTCTCATTTAAAAGGAATTGAAGAAGAA ATAAAATGGCAGAGGTTTAAGGTTACTATTCAGGATGACTGATGATAATTCAGATGATAAAATAGAAGATGAATTGCAAACCTTCTTTACCAGTGATAAA GATGGAAATACACATGCATACAACCCGAAATCACCACCTACACAAAACTCTTCAGCCAGCAGTGTGAACTGGAATTCTGCCAACCCAGATGACATGGTGG TTGATTATGAAACTGACCCTGCTGTAGTTACTGGTGAAAATATTTCTTTAAGCCTTCAGGGTGTTGAAGTATTTGGTCATGAAAAGTCTTCTAGTGATTT CATTAGTAAGCAGGTGTTAGATATGCATAAAGATTCTATTTGTCAGTGTCCTGCACTTGTAGGTACTGAGAAGCCCAAATATCTGCAACACAGTTGTCAT TCCCTAGAAGCAGTTGAGGGCCAGAGTGTTGAGCCATCTTTGCCTTTTGTGTGGAAGCCTAATGACAATTTGAACTGTGCAGGCTACTGTGATGCCTTGG AGCTAAACCAAACATTTGACATGACAGTGGATAAAGTTAACTGCACCTTTATATCACATCATGCCATCGGAAAGAGTCAGTCCTTCCATACTGCTGGAAG CCTGCCACCAACTGGTAGGAGAAGTGGAAGTACATCTTCTTTATCCTATTCCACTTGGACATCTTCCCATTCTGATAAGACGCATGCAAGAGAAACTACT TATGATAGAGAAAGCTTTGAAAACCCTCAAGTCACACCATCAGAAGCCCAAGACATGACTTACACAGCATTTTCTGATGTGGTGATGCAAAGTGAGGTTT TTGTTTCAGATATTGGAAATCAGTGTGCATGTTCTTCAGGAAAGGTCACCAGTGAGTACACAGATGGATCACAACAAAGACTAGTTGGAGAAAAGGAGAC ACAAGCACTAACACCAGTTTCTGATGGCATGGAAGTCCCCAATGATTCTGCATTACAAGAGTTCTTTTGTTTATCCCATGATGAATCCAATAGCGAACCA CATTCACAGAGCTCATACAGGCACAAGGAAATGGGCCAAAATCTGAGAGAGACAGTGTCCTATTGTCTTATTGATGATGAATGCCCTTTAATGGTGCCAG CTTTTGATAAGAGCGAAGCTCAAGTGCTGAACCCAGAGCATAAAGTCACTGAGACTGAAGACACACAAATGGTCTCCAAAGGAAAGGATTTGGGAACCCA AAATCATACCTCAGAATTGATTCTAAGTAGCCCGCCAGGACAAAAGGTGGGCTCGTCATTTGGACTGACTTGGGATGCAAATGATATGGTCATTAGCACA GACAAAACGATGTGCATGTCAACACCAGTCCTAGAACCCACAAAAGTAACCTTTTCTGTTTCACCGATTGAAGCGACGGAGAAATGTAAGAAAGTGGAGA AGGGTAATCGAGGGCTTAAAAACATACCAGACTCGAAGGAGGCACCTGTGAACCTGTGTAAACCCAGTTTAGGAAAATCAACAATCAAAACGAATACCCC AATAGGCTGCAAAGTTAGAAAAACTGAAATTATAAGTTACCCAAGACCAAACTTCAAGAATGTCAAAGCAAAAGTTATGTCTAGAGCAGTGTTGCAGCCC AAAGATGCTGCTTTATCAAAGGTCACGCCCAGACCTCAGCAGACCAGTGCCTCATCACCCTCATCAGTGAATTCAAGACAACAAACAGTCTTGAGCAGAA CACCGAGATCTGACTTGAATGCAGACAAAAAAGCAGAAATTCTAATTAACAAGACACATAAGCAGCAGTTTAATAAACTCATTACTAGCCAGGCTGTGCA TGTTACAACTCATTCTAAAAATGCTTCACACAGGGTTCCAAGAACAACATCTGCCGTGAAATCGAATCAGGAAGATGTTGACAAAGCCAGTTCTTCTAAC TCAGCATGCGAGACCGGGTCCGTTTCTGCGTTGTTTCAGAAGATCAAAGGCATACTCCCTGTTAAAATGGAAAGTGCAGAATGTTTGGAAATGACCTATG TTCCCAACATTGATAGGATTAGCCCTGAAAAGAAGGGTGAAAAAGAAAATGGGACATCTATGGAAAAACAAGAGCTGAAACAAGAGATTATGAATGAGAC TTTTGAATATGGTTCTCTGTTTTTGGGCTCTGCTTCAAAAACAACGACCACCTCAGGTAGGAATATATCCAAGCCTGACTCCTGCGGTTTGAGGCAAATA GCTGCTCCAAAAGCCAAAGTGGGGCCCCCTGTTTCCTGTTTGAGGCGGAACAGTGACAATAGAAATCCCAGTGCTGATCGAGCCGTATCTCCTCAGAGGA TCAGGCGTGTGTCCAGTTCTGTTTTGCCAAAAGCTGCTTTCTCATGATTATTCTGATTGATCATCTCCTTCAGAGAACATGTGAAAGCCTACATCCTTGA AAACTGCACAGTCGTCATGGGTGAATTTGCCTAGACCACTTCCTAAATCCAAAGCATCTTTGAAAAGTCCTGCGCTGCGGAGGACAGGAAGCACCCCCTC AATAGCCAGCACCCACAGTGAGCTGAGCACTTACAGCAACAATTCTGGTAATGCCGCTGTCATCAAATATGAGGAGAAACCTCCAAAACCAGCATTTCAG AATGGTTCCTCAGGATCCTTTTATTTGAAGCCTTTGGTATCCAGGGCTCATGTTCACTTGATGAAAACTCCTCCAAAAGGTCCTTCGAGAAAAAATTTAT TTACAGCTCTTAATGCAGTTGAAAAGAGCAGGCAAAAGAATCCTCGAAGCTTATGTATCCAGCCACAGACAGCTCCCGATGCGCTGCCCCCTGAGAAAAC ACTTGAATTGACGCAATATAAAACAAAATGTGAAAACCAAAGTGGATTTATCCTGCAGCTCAAGCAGCTTCTTGCCTGTGGTAATACCAAGTTTGAGGCA TTGACAGTTGTGATTCAGCACCTGCTGTCTGAGCGGGAGGAAGCACTGAAACAACACAAAACCCTATCTCAAGAACTTGTTAACCTCCGGGGAGAGCTAG TCACTGCTTCAACCACCTGTGAGAAATTAGAAAAAGCCAGGAATGAGTTACAAACAGTGTATGAAGCATTCGTCCAGCAGCACCAGGCTGAAAAAACAGA ACGAGAGAATCGGCTTAAAGAGTTTTACACCAGGGAGTATGAAAAGCTTCGGGACACTTACATTGAAGAAGCAGAGAAGTACAAAATGCAATTGCAAGAG CAGTTTGACAACTTAAATGCTGCGCATGAAACCTCTAAGTTGGAAATTGAAGCTAGCCACTCAGAGAAACTTGAATTGCTAAAGAAGGCCTATGAAGCCT CCCTTTCAGAAATTAAGAAAGGCCATGAAATAGAAAAGAAATCGCTTGAAGATTTACTTTCTGAGAAGCAGGAATCGCTAGAGAAGCAAATCAATGATCT GAAGAGTGAAAATGATGCTTTAAATGAAAAATTGAAATCAGAAGAACAAAAAAGAAGAGCAAGAGAAAAAGCAAATTTGAAAAATCCTCAGATCATGTAT CTAGAACAGGAGTTAGAAAGCCTGAAAGCTGTGTTAGAGATCAAGAATGAGAAACTGCATCAACAGGACATCAAGTTAATGAAAATGGAGAAACTGGTGG ACAACAACACAGCATTGGTTGACAAATTGAAGCGTTTCCAGCAGGAGAATGAAGAATTGAAAGCTCGGATGGACAAGCACATGGCAATCTCAAGGCAGCT TTCCACGGAGCAGGCTGTTCTGCAAGAGTCGCTGGAGAAGGAGTCGAAAGTCAACAAGCGACTCTCTATGGAAAACGAGGAGCTTCTGTGGAAACTGCAC AATGGGGACCTGTGTAGCCCCAAGAGATCCCCCACATCCTCCGCCATCCCTTTGCAGTCACCAAGGAATTCGGGCTCCTTCCCTAGCCCCAGCATTTCAC CCAGATGACACCTCCCCAAAGTCCACAGACTCTCTGAAAGCATTTTGATGCAGGTCTGCAGGACTGACCCCAAGGAGGAACGTGGGCACAAGAGGTATAT CAGCACACGTGTGATCACCGTAGGGTAACTGGAGCGTCACCACCGGCGGAATCGCAGCTTCTGAGACTGGAACTCTGGAGGAAGACTTTTGCCTCCGTCC AAAAGATTCCTCCAAAAAAAGATTTAAAAAAAGATTTCGGCATCGACACGGACGTTGTTGCACAAAGCACTTAAAGAACGAGAGCATCTTGTTCATTGCC TTTTTCACCTAAGCATAGGGGGAAAAACTCTCAGGGCCCTATTAAGATTTATAACCTTTGTAATGTTCTTCACCACAGACACCTTCTTGTGAGTTTTCAG TCTGACTGTGGGGGTGGGGGGTGTGAATGAAATGGATGTCACAGAGTGTCATGTGTCTGATGCAGCCTCCTCTGCTGTGTATTAAATGTCAAAATCTGAA TATATCTGGATATGTACTAATCAAATAATAATCAATCAATCAGCATATACATTTCAGCCAAAGCCATAGAAGAAAAAGCAATAGTTGCTTGAATTATGAT CATCTACCACCAACTCTGCTCAGCCCTGTAACAGGGTAGGGAGAGGGTATAACAGGAAGAGCTTTGACTTGTCCCTGTCTATACATTCTCTGTATCTTTT GGGGGTAACTTCTTGGCAGTTTTTCAGTGTTCAGCCATGTCAGTTGAAACTAGATTTTTCTGTAGATTTTTTACTTACCCATGTGAGCCTAACACTATCC TGTAATTCATTTTCTCAGGCTATGTGTAAATGTAGAACCCTAATTTTTCTATAAAAAAACAAACTAACTAACTAACTGTGTAAAGAAAGAAAAAGGGAAG TACCAATGGGTTTTTCCACCTTATTTTTACCTTTGATCTACCCTTGCAGATTTAACCTGTCTTCTTCCCTCCCATTATTCTCATTTTCCTTTTACCTTTC TCCACCATCCAGAGCCACAAAAGCAAACCTTCTACCTCCTACCTACTTTTCTCTGGGACAAGGATAAAGGAATATGATTTTCCAGAGCCCCAGAGCCAGC TCATCTTCCAGGTGCTGAAACCACTTTCCAAATAAACTAAAGCCTGGATTTGATATTACAAATTTTGGGAAATCTTAGAATAAAGAACGAGAACAAGGAA GTCATTGGCTAGTATAATTAAGAAAGGTAGGATTCAGTGCTTACCGATGATGCAGTACTTGATAGAAGAAAACAGTCTGGGAGGATAGCGCTCATTTTTC AGTTACCCTTTAAGGAGTCCCTTTGTCTTTGGGAAAGTAGCAGAATGGTCCGCTTCTTTCCCATGAGTGGAAAATGTGGCTTGTCCAACTCTCCTCCAGG TTGCATTTCAGTTTCTTTCCAAAACTTATTACCTCCCCTAATCCTGAGACTTTGGAAAAGGTGGAAGGAAGAACTGTTGCTTTATCTCCCCCTCCCTGCA TGTGTCAACATTGTGATGTCAGTATTTACTAATCTACATTCAGTGGCTGTACAAATAACAGCTGTAGTAAGAAGAGATTCAGGATGCTAGAGGTGAATAT TTGGGTCATTTACATGTACACTACATAGCAAGTTGATACTCATGTTGCATGTTCTTTTAAATTAGTGATTTTGTGTCTTAAGTCTTTAACTTCCAATACT TCATCATGTATGTAACCTTCCATGTTTGCTTCTGATAAATGGAAATGTAGGTTCACTGCCACTTCATGAGATATCTCTGCTCACGCTTCCAAGTTGTTCT CAATGACATTAGCCAAAGTTGGGTTTGCCATTCATCCCCTAGGCATGGTAAATCTTGTGTTGTTCCCTGCTGTCCTCCGTATTACGTGACCGGCAAATAA ATCTCATAGCAGTTAATATAAAACATCTTTGGAGGATGGGAGAGAACAGGAGGGAAGATGGGAAACAAAATAGAGAATTCTTAAGATTTTGTTTAAACCA AATGTTTCATGTAGAATGCAAAATGTTGGCACGTCAAAAATATGAATGTGTAGACAACTGTAGTTGTGCTCAGTTTGTAGTGATGGGAAGTGTATTTTAC TCTGATCAAATAAATAATGCTGGAATACTCAAGAATTGCA

refseq_MTUS1.F2 (forward primer)
refseq_MTUS1.R2 (reverse primer)
Single exon skipping

Frame 0

RGPAQSLRKGRMRISSLSP*K*PRGLTVDSLRR PPGPGGPSLLAGPLLSRSKRGRESGWNRVAAGPK DPSWRLATFCSLFALFHALEKSHLN*GNNKSFN LQSILD*KPFNCAEKPRRQTILPTLSFKRN*RR NKMAEV*GYYSG*LMIIQMIK*KMNCKPSLPVIK MEIHMHTTRNHHLHKTLQPAV*TGILPTQMTWW LIMKLTLL*LLVKIFL*AFRVLKYLVMKSLLVI SLVSRC*ICIKILFVSVLHL*VLRSPNICNTVVI P*KQLRARVLSHLCLLCGSLMTI*TVQATVMPW S*TKHLT*QWIKLTAPLYHIMPSERVSPSILLE ACHQLVGEVEVHLLYPIPLGHLPILIRRMQEKLL MIEKALKTLKSHHQKPKT*LTQHFLMW*CKVRF LFQILEISVHVLQERSPVSTQMDHNKD*LEKRR HKH*HQFLMAWKSPMILHYKSSFVYPMMNPIANH IHRAHTGTRKWAKI*ERQCPIVLLMMNAL*WCQ LLIRAKLKC*TQSIKSLRLKTHKWSPKERIWEP KIIPQN*F*VARQDKRWARHLD*LGMQMIWSLAQ TKRCACQHQS*NPQK*PFLFHRLKRRRNVRKWR RVIEGLKTYQTRRRHL*TCVNPV*ENQQSKRIP Q*AAKLEKLKL*VTQDQTSRMSKQKLCLEQCCSP KMLLYQRSRPDLSRPVPHHPHQ*IQDNKQS*AE HRDLT*MQTKKQKF*LTRHISSSLINSLLARLC MLQLILKMLHTGFQEQHLP*NRIRKMLTKPVLLT QHARPGPFLRCFRRSKAYSLLKWKVQNVWK*PM FPTLIGLALKRRVKKKMGHLWKNKS*NKRL*MR LLNMVLCFWALLQKQRPPQVGIYPSLTPAV*GK* LLQKPKWGPLFPV*GGTVTIEIPVLIEPYLLRG SGVCPVLFCQKLLSHDYSD*SSPSENM*KPTSL KTAQSSWVNLPRPLPKSKASLKSPALRRTGSTPS IASTHSELSTYSNNSGNAAVIKYEEKPPKPAFQ NGSSGSFYLKPLVSRAHVHLMKTPPKGPSRKNL FTALNAVEKSRQKNPRSLCIQPQTAPDALPPEKT LELTQYKTKCENQSGFILQLKQLLACGNTKFEA LTVVIQHLLSEREEALKQHKTLSQELVNLRGEL VTASTTCEKLEKARNELQTVYEAFVQQHQAEKTE RENRLKEFYTREYEKLRDTYIEEAEKYKMQLQE QFDNLNAAHETSKLEIEASHSEKLELLKKAYEA SLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDL KSENDALNEKLKSEEQKRRAREKANLKNPQIMY LEQELESLKAVLEIKNEKLHQQDIKLMKMEKLV DNNTALVDKLKRFQQENEELKARMDKHMAISRQL STEQAVLQESLEKESKVNKRLSMENEELLWKLH NGDLCSPKRSPTSSAIPLQSPRNSGSFPSPSIS PR*HLPKVHRLSESILMQVCRTDPKEERGHKRYI STRVITVG*LERHHRRNRSF*DWNSGGRLLPPS KRFLQKKI*KKISASTRTLLHKALKEREHLVHC LFHLSIGGKTLRALLRFITFVMFFTTDTFL*VFS LTVGVGGVNEMDVTECHVSDAASSAVY*MSKSE YIWICTNQIIINQSAYTFQPKP*KKKQ*LLEL* SSTTNSAQPCNRVGRGYNRKSFDLSLSIHSLYLL GVTSWQFFSVQPCQLKLDFSVDFLLTHVSLTLS CNSFSQAMCKCRTLIFL*KNKLTN*LCKERKRE VPMGFSTLFLPLIYPCRFNLSSSLPLFSFSFYLS PPSRATKANLLPPTYFSLGQG*RNMIFQSPRAS SSSRC*NHFPNKLKPGFDITNFGKS*NKEREQG SHWLV*LRKVGFSAYR*CST**KKTVWEDSAHFS VTL*GVPLSLGK*QNGPLLSHEWKMWLVQLSSR LHFSFFPKLITSPNPETLEKVEGRTVALSPPPC MCQHCDVSIY*STFSGCTNNSCSKKRFRMLEVNI WVIYMYTT*QVDTHVACSFKLVILCLKSLTSNT SSCM*PSMFASDKWKCRFTATS*DISAHASKLF SMTLAKVGFAIHPLGMVNLVLFPAVLRIT*PANK SHSS*YKTSLEDGREQEGRWETK*RILKILFKP NVSCRMQNVGTSKI*MCRQL*LCSVCSDGKCIL L*SNK*CWNTQEL

Frame 1

VGQRRACGRDGCGSRRCHLESDRGA*LWTPYAA HPGPAVPAFSQGPFSAEASGAEKAGGIGLLQVP KTPRGASLLSAACLHFFTL*KNLILIKGTTNHLI FRAS*TENLSTVLKNLEDRPFCPPSHLKGIEEE IKWQRFKVTIQDD***FR**NRR*IANLLYQ** RWKYTCIQPEITTYTKLFSQQCELEFCQPR*HGG *L*N*PCCSYW*KYFFKPSGC*SIWS*KVF**F H**AGVRYA*RFYLSVSCTCRY*EAQISATQLS FPRSS*GPEC*AIFAFCVEA**QFELCRLL*CLG AKPNI*HDSG*S*LHLYITSCHRKESVLPYCWK PATNW*EKWKYIFFILFHLDIFPF**DACKRNY L**RKL*KPSSHTIRSPRHDLHSIF*CGDAK*GF CFRYWKSVCMFFRKGHQ*VHRWITTKTSWRKGD TSTNTSF*WHGSPQ*FCITRVLLFIP**IQ*RT TFTELIQAQGNGPKSERDSVLLSY***MPFNGAS F**ERSSSAEPRA*SH*D*RHTNGLQRKGFGNP KSYLRIDSK*PARTKGGLVIWTDLGCK*YGH*H RQNDVHVNTSPRTHKSNLFCFTD*SDGEM*ESGE G*SRA*KHTRLEGGTCEPV*TQFRKINNQNEYP NRLQS*KN*NYKLPKTKLQECQSKSYV*SSVAA QRCCFIKGHAQTSADQCLITLISEFKTTNSLEQN TEI*LECRQKSRNSN*QDT*AAV**THY*PGCA CYNSF*KCFTQGSKNNICREIESGRC*QSQFF* LSMRDRVRFCVVSEDQRHTPC*NGKCRMFGNDLC SQH**D*P*KEG*KRKWDIYGKTRAETRDYE*D F*IWFSVFGLCFKNNDHLR*EYIQA*LLRFEAN SCSKSQSGAPCFLFEAEQ*Q*KSQC*SSRISSED QACVQFCFAKSCFLMIILIDHLLQRTCESLHP* KLHSRHG*ICLDHFLNPKHL*KVLRCGGQEAPP Q*PAPTVS*ALTATILVMPLSSNMRRNLQNQHFR MVPQDPFI*SLWYPGLMFT**KLLQKVLREKIY LQLLMQLKRAGKRILEAYVSSHRQLPMRCPLRK HLN*RNIKQNVKTKVDLSCSSSSFLPVVIPSLRH *QL*FSTCCLSGRKH*NNTKPYLKNLLTSGES* SLLQPPVRN*KKPGMSYKQCMKHSSSSTRLKKQ NERIGLKSFTPGSMKSFGTLTLKKQRSTKCNCKS SLTT*MLRMKPLSWKLKLATQRNLNC*RRPMKP PFQKLRKAMK*KRNRLKIYFLRSRNR*RSKSMI *RVKMML*MKN*NQKNKKEEQEKKQI*KILRSCI *NRS*KA*KLC*RSRMRNCINRTSS**KWRNWW TTTQHWLTN*SVSSRRMKN*KLGWTSTWQSQGS FPRSRLFCKSRWRRSRKSTSDSLWKTRSFCGNCT MGTCVAPRDPPHPPPSLCSHQGIRAPSLAPAFH PDDTSPKSTDSLKAF*CRSAGLTPRRNVGTRGI SAHV*SP*GNWSVTTGGIAASETGTLEEDFCLRP KDSSKKRFKKRFRHRHGRCCTKHLKNESILFIA FFT*A*GEKLSGPY*DL*PL*CSSPQTPSCEFS V*LWGWGV*MKWMSQSVMCLMQPPLLCIKCQNLN ISGYVLIK**SINQHIHFSQSHRRKSNSCLNYD HLPPTLLSPVTG*GEGITGRALTCPCLYILCIF WG*LLGSFSVFSHVS*N*IFL*IFYLPM*A*HYP VIHFLRLCVNVEP*FFYKKTN*LTNCVKKEKGK YQWVFPPYFYL*STLADLTCLLPSHYSHFPFTF LHHPEPQKQTFYLLPTFLWDKDKGI*FSRAPEPA HLPGAETTFQIN*SLDLILQILGNLRIKNENKE VIG*YN*ER*DSVLTDDAVLDRRKQSGRIALIF QLPFKESLCLWESSRMVRFFPMSGKCGLSNSPPG CISVSFQNLLPPLILRLWKRWKEELLLYLPLPA CVNIVMSVFTNLHSVAVQITAVVRRDSGC*R*I FGSFTCTLHSKLILMLHVLLN**FCVLSL*LPIL HHVCNLPCLLLINGNVGSLPLHEISLLTLPSCS Q*H*PKLGLPFIP*AW*ILCCSLLSSVLRDRQI NLIAVNIKHLWRMGENRREDGKQNREFLRFCLNQ MFHVECKMLARQKYECVDNCSCAQFVVMGSVFY SDQINNAGILKNC

Frame 2

WASAEPAEGTDADLVAVTLKVTEGLDCGLLTPP TRARRSQPSRRAPSQQKQAGPRKRVE*GCCRSQ RPLVAPRYFLQLVCTFSRSRKISS*LREQQII* SSEHLRLKTFQLC*KT*KTDHFAHPLI*KELKKK *NGRGLRLLFRMTDDNSDDKIEDELQTFFTSDK DGNTHAYNPKSPPTQNSSASSVNWNSANPDDMV VDYETDPAVVTGENISLSLQGVEVFGHEKSSSDF ISKQVLDMHKDSICQCPALVGTEKPKYLQHSCH SLEAVEGQSVEPSLPFVWKPNDNLNCAGYCDAL ELNQTFDMTVDKVNCTFISHHAIGKSQSFHTAGS LPPTGRRSGSTSSLSYSTWTSSHSDKTHARETT YDRESFENPQVTPSEAQDMTYTAFSDVVMQSEV FVSDIGNQCACSSGKVTSEYTDGSQQRLVGEKET QALTPVSDGMEVPNDSALQEFFCLSHDESNSEP HSQSSYRHKEMGQNLRETVSYCLIDDECPLMVP AFDKSEAQVLNPEHKVTETEDTQMVSKGKDLGTQ NHTSELILSSPPGQKVGSSFGLTWDANDMVIST DKTMCMSTPVLEPTKVTFSVSPIEATEKCKKVE KGNRGLKNIPDSKEAPVNLCKPSLGKSTIKTNTP IGCKVRKTEIISYPRPNFKNVKAKVMSRAVLQP KDAALSKVTPRPQQTSASSPSSVNSRQQTVLSR TPRSDLNADKKAEILINKTHKQQFNKLITSQAVH VTTHSKNASHRVPRTTSAVKSNQEDVDKASSSN SACETGSVSALFQKIKGILPVKMESAECLEMTY VPNIDRISPEKKGEKENGTSMEKQELKQEIMNET FEYGSLFLGSASKTTTTSGRNISKPDSCGLRQI AAPKAKVGPPVSCLRRNSDNRNPSADRAVSPQR IRRVSSSVLPKAAFS*LF*LIISFREHVKAYILE NCTVVMGEFA*TTS*IQSIFEKSCAAEDRKHPL NSQHPQ*AEHLQQQFW*CRCHQI*GETSKTSIS EWFLRILLFEAFGIQGSCSLDENSSKRSFEKKFI YSS*CS*KEQAKESSKLMYPATDSSRCAAP*EN T*IDAI*NKM*KPKWIYPAAQAASCLW*YQV*G IDSCDSAPAV*AGGSTETTQNPISRTC*PPGRAS HCFNHL*EIRKSQE*VTNSV*SIRPAAPG*KNR TRESA*RVLHQGV*KASGHLH*RSREVQNAIAR AV*QLKCCA*NL*VGN*S*PLRET*IAKEGL*SL PFRN*ERP*NRKEIA*RFTF*EAGIAREANQ*S EE*K*CFK*KIEIRRTKKKSKRKSKFEKSSDHV SRTGVRKPESCVRDQE*ETASTGHQVNENGETGG QQHSIG*QIEAFPAGE*RIESSDGQAHGNLKAA FHGAGCSARVAGEGVESQQATLYGKRGASVETA QWGPV*PQEIPHILRHPFAVTKEFGLLP*PQHFT QMTPPQSPQTL*KHFDAGLQD*PQGGTWAQEVY QHTCDHRRVTGASPPAESQLLRLELWRKTFASV QKIPPKKDLKKDFGIDTDVVAQST*RTRASCSLP FSPKHRGKNSQGPIKIYNLCNVLHHRHLLVSFQ SDCGGGGCE*NGCHRVSCV*CSLLCCVLNVKI* IYLDMY*SNNNQSISIYISAKAIEEKAIVA*IMI IYHQLCSAL*QGRERV*QEEL*LVPVYTFSVSF GGNFLAVFQCSAMSVETRFFCRFFTYPCEPNTI L*FIFSGYV*M*NPNFSIKKQTN*LTV*RKKKGS TNGFFHLIFTFDLPLQI*PVFFPPIILIFLLPF STIQSHKSKPSTSYLLFSGTRIKEYDFPEPQSQ LIFQVLKPLSK*TKAWI*YYKFWEILE*RTRTRK SLASIIKKGRIQCLPMMQYLIEENSLGG*RSFF SYPLRSPFVFGKVAEWSASFP*VENVACPTLLQ VAFQFLSKTYYLP*S*DFGKGGRKNCCFISPSLH VSTL*CQYLLIYIQWLYK*QL**EEIQDARGEY LGHLHVHYIAS*YSCCMFF*ISDFVS*VFNFQY FIMYVTFHVCF**MEM*VHCHFMRYLCSRFQVVL NDISQSWVCHSSPRHGKSCVVPCCPPYYVTGK* IS*QLI*NIFGGWERTGGKMGNKIENS*DFV*T KCFM*NAKCWHVKNMNV*TTVVVLSL**WEVYFT LIK*IMLEYSRIA