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Sequences

Sequence NM_016156

TGCACTCTGGGGGAACATGGCCGCTTCCGGTCTCCCTCCCGGGCCGGCGCTGGCCTGACTGCGGCCCCGGTCCGTAGCACTCCGCCCTCCGCTTCTCCCG
CCCTGTAGCCGCGAAGACTGCTTCAGCCTTTCCCTGTGCTGCCCCTGCCGCGCGATGGAGAAGAGCTCGAGCTGCGAGAGTCTTGGCTCCCAGCCGGCGG
CGGCTCGGCCGCCCAGCGTGGACTCCTTGTCCAGTGCCTCCACTTCTCATTCAGAGAATTCAGTGCATACAAAATCAGCTTCTGTTGTATCATCAGATTC
CATTTCAACTTCTGCCGACAACTTTTCTCCTGATTTGAGGGTCCTGAGGGAGTCTAACAAGTTAGCAGAAATGGAAGAACCACCCTTGCTTCCAGGAGAA
AATATTAAAGACATGGCCAAAGATGTAACTTATATATGTCCATTCACTGGCGCTGTACGAGGAACTCTGACTGTCACGAATTATAGGTTATATTTCAAAA
GCATGGAACGGGATCCCCCATTTGTTTTAGATGCTTCCCTTGGTGTGATAAATAGAGTAGAAAAAATTGGTGGTGCTTCTAGTCGAGGTGAAAATTCTTA
TGGACTAGAAACTGTGTGTAAGGATATTAGGAATTTACGATTTGCTCATAAACCTGAGGGGCGGACAAGAAGATCCATATTTGAGAATCTAATGAAATAT
GCATTTCCTGTCTCTAATAACCTGCCTCTTTTTGCTTTTGAATACAAAGAAGTATTCCCTGAAAATGGGTGGAAGCTATATGACCCTCTTTTAGAGTATA
GAAGGCAGGGAATTCCAAATGAAAGCTGGAGAATAACAAAGATAAATGAACGATATGAACTTTGTGATACATACCCTGCCCTCCTGGTTGTGCCAGCAAA
TATTCCTGATGAAGAATTAAAGAGAGTGGCATCCTTCAGATCAAGAGGCCGTATCCCAGTTTTATCATGGATTCATCCTGAAAGTCAAGCCACAATCACT
CGGTGTAGCCAGCCCATGGTTGGAGTGAGTGGAAAGCGAAGCAAAGAAGATGAAAAATACCTTCAAGCTATCATGGATTCCAATGCCCAGTCTCACAAAA
TCTTTATATTTGATGCCCGGCCAAGTGTTAATGCTGTTGCCAACAAGGCAAAGGGTGGAGGTTATGAAAGTGAAGATGCCTATCAAAATGCTGAACTAGT
TTTCCTGGATATCCACAATATTCATGTTATGAGAGAATCATTACGAAAACTTAAGGAGATTGTGTACCCCAACATTGAGGAAACCCACTGGTTGTCTAAC
TTGGAATCTACTCATTGGCTAGAACATATTAAGCTTATTCTTGCAGGGGCTCTTAGGATTGCTGACAAGGTAGAGTCAGGGAAGACGTCTGTGGTAGTGC
ATTGCAGTGATGGTTGGGATCGCACAGCTCAGCTCACTTCCCTTGCCATGCTCATGTTGGATGGATACTATCGAACCATCCGAGGATTTGAAGTCCTTGT
GGAGAAAGAATGGCTAAGTTTTGGACATCGATTTCAACTAAGAGTTGGCCATGGAGATAAGAACCATGCAGATGCAGACAGATCGCCTGTTTTTCTTCAA
TTTATTGACTGTGTCTGGCAGATGACAAGACAGTTTCCTACCGCATTTGAATTCAATGAGTATTTTCTCATTACCATTTTGGACCACCTATACAGCTGCT
TATTCGGAACATTCCTCTGTAATAGTGAACAACAGAGAGGAAAAGAGAATCTTCCTAAAAGGACTGTGTCACTGTGGTCTTACATAAACAGCCAGCTGGA
AGACTTCACTAATCCTCTCTATGGGAGCTATTCCAATCATGTCCTTTATCCAGTAGCCAGCATGCGCCACCTAGAGCTCTGGGTGGGATATTACATAAGG
TGGAATCCACGGATGAAACCACAGGAACCTATTCACAACAGATACAAAGAACTTCTTGCTAAACGAGCAGAGCTTCAGAAAAAAGTAGAGGAACTACAGA
GAGAGATTTCTAACCGATCAACCTCATCCTCAGAGAGAGCCAGCTCTCCTGCACAGTGTGTCACTCCTGTCCAAACTGTTGTATAAAGGACTGTAAGATC
AGGGGCATCATTGCTATACACTCTTGATTACACTGGCAGCTCTATGAGTAGAAAGTCTTCGGAATTTAGAACCCATCTATGAGAGAAAGTTCAGTCACTT
TATTTATTTTAAATCTCTCTAGGATGAGTTTAGAACTGTAGCAGTGCAGGTGGCTTAAGTGAAGTAACTCCATATGTAATTACATGATTATGATACTAAT
CTTTTAAGTATCCAAAGAATATTAAAATACTTCAATCCTGGATTCACAGTGGGAACAAGTTTCTATTAAAAGGCAAATGCTGTTACAAATTTTTGGCATC
TGGTAATATTAAAACCATTTTAGAAATACACTCTGTGCTCACTGTGCAGAGGAACATCAGTTTTCAAACCAACACTGAAATTCTGTGGCATCACATATAT
TGGGCCTTGATGTCATGACAGATCAAAATCATTTGATATCCCTTTCTCCATTCTAGGTTTTTCTTTTTTTCAGTAACTGATTTACCTTGATCACTTTTCA
ACTTCCATATTCTTCATATAGTAAAAGGCAAAGTGTTGAAGATACTACGGTGTGGTAGTAGTTGAAAATTATTGCCGTCATTATTTACATACTTAAGACA
TATTAGCAAGTTGATCCAAAATGGGAGGCCTTATAGATGTGCTTGGGGGAAAATGAAGGGGAGAAAGTAGCCATACAGGAGTTCAAAGAATTCCATGCCC
TTCAGATTAGCCCAATTACCAGAAACATCATGAAAGATATTTTAAAAACTAATTATTTACTACAGTGTATTTCACTTGTCTTGTGTGTCTGAACACACAG
AAGCTAATTAGCAAGTTTTTAAGAAGTATTTAAAAATCTTACTAGGATTGACATTTTTTCTGAATTCTGTATAAATAGCTTATAGTGAGAAGTACTGTGC
TCAAATTTTACATTTTTTTCCTTTGCAAATTCTGTAATTTCACTCAACGATTAAGTCTACCAAAGAACACACTGCATGTAAAAGATGTATTACAATCTCA
AAGCCAGTAAAAGAAATCTTGCTTCACTGTTCACCTGCTACAAGTAAGAGTTTGGTGCTGGTAGAAACATTTGACTCTGATGTCTATTTTATTCTACATA
AGAGCCATATGTAATGTACTGTAACAAAGGAGCTTCTTGTCCCCTTGGTCTTTTAATTAAAAGAAATTCCAACTGACTTTTAAACTTTGTTCTTGTCCAA
AGTTGCCATTTCTTTTTTTTCCCCAGAAATATTTGGAAATTATTGGAGGAATATGCACCCCAGATGAAAATGTTCAGTTTGTACCCATTTTTCCTTAACC
AACACCCAAATCAAACAATTAAAATATACAGTGTTTTTCCACTCACTAATTCACTATACAGAGAGTCTGAACCTTAGCCTCCCTCTTGGTCTTGCAGTGA
GGAAGTTTCTATTAGTATATCCAATTTAGCAAAATTGGTACCAAAATGATTTCTTTGGTAATTGTGTGAAATATAAGCTTTTTAACAGGGCATTTAAGTG
GCTAGCAAATCAGTAATTAAAAATTAAGCTTTCTACTCCAAGTATTTCACAAACGCATCTGCCATTTTCCTCATTTAAACCTTGGTTATCTTGGCCTGAT
ACCACATAAAAGAATGTAGAATGGCTGAAGAGATCAAGAATTTAAAGCTTCTAGTCTTAACATACTTGCATCCACTTCAAATTCAAATCAAAAGCCAGGG
AAATCTAAGTGCAACCCTACCACTTCTCTGCTGAGAACCTTCCAGTGGTTCCCCTCACCTTCTGCAGAAGTCTCCAATATGGAGTACATGCACTTGGGCA
TTTAATATATACCACTGGTGTGTGTGGGAGGGAGGGAGGAGGAATACTAGCCCTTTTTATATATTTACACAAGCAAAACTTTTAAATATTTGAATTGACA
GTTACATGTTTCATAACTTTGTATGTCTATTGGTTGTGCAGGTGTAATTTTTTCCCTTTTTGATTAGGGTTACAAAATTTAGAGACCAGTATGATTAAGT
TGAAGCTCCTTAGCCTCCTTCGACCTAGTCTCTGCATACCTCAACTTTTACGTACCAATGCTACTCTGCTGTTCACAATTGCCTCATGTAATCTGCAGAT
TCCTGCCTCCCCACTTTGGTTCAGTCTGTCTTGTGCACCTGGAACAACTGTTCTCCCTTGTGACTAATTCCTATTTTCTAGAGTTTAGGCATCATCTCTT
CCTTTGGGAAGTTATCTGATTCACGACTGCCTTCTCTGACATCCCCACCTTCCTCTGTGCCCCCATAGCACTGTGTATACCGCTACTACCACTGCAATTC
ACATTATATTGGAATGAACAATTCACATGTCTACCACAAGTCTGTAAACATAACCTTATTTGAAATGAATTGCAATAAAGCTCTGTTACAACGT
  • refseq_MTMR2.F1 (forward primer)
  • refseq_MTMR2.R1 (reverse primer)
  • Single exon skipping

Frame 0

CTLGEHGRFRSPSRAGAGLTAAPVRSTPPSASP
AL*PRRLLQPFPVLPLPRDGEELELRESWLPAGG
GSAAQRGLLVQCLHFSFREFSAYKISFCCIIRF
HFNFCRQLFS*FEGPEGV*QVSRNGRTTLASRR
KY*RHGQRCNLYMSIHWRCTRNSDCHEL*VIFQK
HGTGSPICFRCFPWCDK*SRKNWWCF*SR*KFL
WTRNCV*GY*EFTICS*T*GADKKIHI*ESNEI
CISCL**PASFCF*IQRSIP*KWVEAI*PSFRV*
KAGNSK*KLENNKDK*TI*TL*YIPCPPGCASK
YS**RIKESGILQIKRPYPSFIMDSS*KSSHNH
SV*PAHGWSEWKAKQRR*KIPSSYHGFQCPVSQN
LYI*CPAKC*CCCQQGKGWRL*K*RCLSKC*TS
FPGYPQYSCYERIITKT*GDCVPQH*GNPLVV*
LGIYSLARTY*AYSCRGS*DC*QGRVREDVCGSA
LQ*WLGSHSSAHFPCHAHVGWILSNHPRI*SPC
GERMAKFWTSISTKSWPWR*EPCRCRQIACFSS
IY*LCLADDKTVSYRI*IQ*VFSHYHFGPPIQLL
IRNIPL***TTERKRESS*KDCVTVVLHKQPAG
RLH*SSLWELFQSCPLSSSQHAPPRALGGILHK
VESTDETTGTYSQQIQRTSC*TSRASEKSRGTTE
RDF*PINLILRESQLSCTVCHSCPNCCIKDCKI
RGIIAIHS*LHWQLYE*KVFGI*NPSMRESSVT
LFILNLSRMSLEL*QCRWLK*SNSICNYMIMILI
F*VSKEY*NTSILDSQWEQVSIKRQMLLQIFGI
W*Y*NHFRNTLCAHCAEEHQFSNQH*NSVASHI
LGLDVMTDQNHLISLSPF*VFLFFSN*FTLITFQ
LPYSSYSKRQSVEDTTVW**LKIIAVIIYILKT
Y*QVDPKWEAL*MCLGENEGEKVAIQEFKEFHA
LQISPITRNIMKDILKTNYLLQCISLVLCV*THR
S*LASF*EVFKNLTRIDIFSEFCINSL**EVLC
SNFTFFSFANSVISLND*VYQRTHCM*KMYYNL
KASKRNLASLFTCYK*EFGAGRNI*L*CLFYST*
EPYVMYCNKGASCPLGLLIKRNSN*LLNFVLVQ
SCHFFFFPRNIWKLLEEYAPQMKMFSLYPFFLN
QHPNQTIKIYSVFPLTNSLYRESEP*PPSWSCSE
EVSISISNLAKLVPK*FLW*LCEI*AF*QGI*V
ASKSVIKN*AFYSKYFTNASAIFLI*TLVILA*
YHIKECRMAEEIKNLKLLVLTYLHPLQIQIKSQG
NLSATLPLLC*EPSSGSPHLLQKSPIWSTCTWA
FNIYHWCVWEGGRRNTSPFYIFTQAKLLNI*ID
SYMFHNFVCLLVVQV*FFPFLIRVTKFRDQYD*V
EAP*PPST*SLHTSTFTYQCYSAVHNCLM*SAD
SCLPTLVQSVLCTWNNCSPL*LIPIF*SLGIIS
SFGKLSDSRLPSLTSPPSSVPP*HCVYRYYHCNS
HYIGMNNSHVYHKSVNITLFEMNCNKALLQR

Frame 1

ALWGNMAASGLPPGPALA*LRPRSVALRPPLLP
PCSREDCFSLSLCCPCRAMEKSSSCESLGSQPA
AARPPSVDSLSSASTSHSENSVHTKSASVVSSDS
ISTSADNFSPDLRVLRESNKLAEMEEPPLLPGE
NIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFK
SMERDPPFVLDASLGVINRVEKIGGASSRGENSY
GLETVCKDIRNLRFAHKPEGRTRRSIFENLMKY
AFPVSNNLPLFAFEYKEVFPENGWKLYDPLLEY
RRQGIPNESWRITKINERYELCDTYPALLVVPAN
IPDEELKRVASFRSRGRIPVLSWIHPESQATIT
RCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHK
IFIFDARPSVNAVANKAKGGGYESEDAYQNAELV
FLDIHNIHVMRESLRKLKEIVYPNIEETHWLSN
LESTHWLEHIKLILAGALRIADKVESGKTSVVV
HCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLV
EKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQ
FIDCVWQMTRQFPTAFEFNEYFLITILDHLYSC
LFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLE
DFTNPLYGSYSNHVLYPVASMRHLELWVGYYIR
WNPRMKPQEPIHNRYKELLAKRAELQKKVEELQ
REISNRSTSSSERASSPAQCVTPVQTVV*RTVRS
GASLLYTLDYTGSSMSRKSSEFRTHL*EKVQSL
YLF*ISLG*V*NCSSAGGLSEVTPYVIT*L*Y*
SFKYPKNIKILQSWIHSGNKFLLKGKCCYKFLAS
GNIKTILEIHSVLTVQRNISFQTNTEILWHHIY
WALMS*QIKII*YPFLHSRFFFFSVTDLP*SLF
NFHILHIVKGKVLKILRCGSS*KLLPSLFTYLRH
ISKLIQNGRPYRCAWGKMKGRK*PYRSSKNSMP
FRLAQLPETS*KIF*KLIIYYSVFHLSCVSEHT
EAN*QVFKKYLKILLGLTFFLNSV*IAYSEKYCA
QILHFFPLQIL*FHSTIKSTKEHTACKRCITIS
KPVKEILLHCSPATSKSLVLVETFDSDVYFILH
KSHM*CTVTKELLVPLVF*LKEIPTDF*TLFLSK
VAISFFSPEIFGNYWRNMHPR*KCSVCTHFSLT
NTQIKQLKYTVFFHSLIHYTESLNLSLPLGLAV
RKFLLVYPI*QNWYQNDFFGNCVKYKLFNRAFKW
LANQ*LKIKLSTPSISQTHLPFSSFKPWLSWPD
TT*KNVEWLKRSRI*SF*S*HTCIHFKFKSKAR
EI*VQPYHFSAENLPVVPLTFCRSLQYGVHALGH
LIYTTGVCGREGGGILALFIYLHKQNF*IFELT
VTCFITLYVYWLCRCNFFPF*LGLQNLETSMIK
LKLLSLLRPSLCIPQLLRTNATLLFTIASCNLQI
PASPLWFSLSCAPGTTVLPCD*FLFSRV*ASSL
PLGSYLIHDCLL*HPHLPLCPHSTVYTATTTAI
HIILE*TIHMSTTSL*T*PYLK*IAIKLCYN

Frame 2

HSGGTWPLPVSLPGRRWPDCGPGP*HSALRFSR
PVAAKTASAFPCAAPAARWRRARAARVLAPSRR
RLGRPAWTPCPVPPLLIQRIQCIQNQLLLYHQI
PFQLLPTTFLLI*GS*GSLTS*QKWKNHPCFQEK
ILKTWPKM*LIYVHSLALYEEL*LSRIIGYISK
AWNGIPHLF*MLPLV**IE*KKLVVLLVEVKIL
MD*KLCVRILGIYDLLINLRGGQEDPYLRI**NM
HFLSLITCLFLLLNTKKYSLKMGGSYMTLF*SI
EGREFQMKAGE*QR*MNDMNFVIHTLPSWLCQQ
IFLMKN*REWHPSDQEAVSQFYHGFILKVKPQSL
GVASPWLE*VESEAKKMKNTFKLSWIPMPSLTK
SLYLMPGQVLMLLPTRQRVEVMKVKMPIKMLN*
FSWISTIFML*ENHYENLRRLCTPTLRKPTGCLT
WNLLIG*NILSLFLQGLLGLLTR*SQGRRLW*C
IAVMVGIAQLSSLPLPCSCWMDTIEPSEDLKSL
WRKNG*VLDIDFN*ELAMEIRTMQMQTDRLFFFN
LLTVSGR*QDSFLPHLNSMSIFSLPFWTTYTAA
YSEHSSVIVNNREEKRIFLKGLCHCGLT*TASW
KTSLILSMGAIPIMSFIQ*PACAT*SSGWDIT*G
GIHG*NHRNLFTTDTKNFLLNEQSFRKK*RNYR
ERFLTDQPHPQREPALLHSVSLLSKLLYKGL*D
QGHHCYTLLITLAAL*VESLRNLEPIYERKFSHF
IYFKSL*DEFRTVAVQVA*VK*LHM*LHDYDTN
LLSIQRILKYFNPGFTVGTSFY*KANAVTNFWH
LVILKPF*KYTLCSLCRGTSVFKPTLKFCGITYI
GP*CHDRSKSFDIPFSILGFSFFQ*LIYLDHFS
TSIFFI**KAKC*RYYGVVVVENYCRHYLHT*D
ILAS*SKMGGLIDVLGGK*RGESSHTGVQRIPCP
SD*PNYQKHHERYFKN*LFTTVYFTCLVCLNTQ
KLISKFLRSI*KSY*D*HFF*ILYK*LIVRSTV
LKFYIFFLCKFCNFTQRLSLPKNTLHVKDVLQSQ
SQ*KKSCFTVHLLQVRVWCW*KHLTLMSILFYI
RAICNVL*QRSFLSPWSFN*KKFQLTFKLCSCP
KLPFLFFPQKYLEIIGGICTPDENVQFVPIFP*P
TPKSNN*NIQCFSTH*FTIQRV*TLASLLVLQ*
GSFY*YIQFSKIGTKMISLVIV*NISFLTGHLS
G*QISN*KLSFLLQVFHKRICHFPHLNLGYLGLI
PHKRM*NG*RDQEFKASSLNILASTSNSNQKPG
KSKCNPTTSLLRTFQWFPSPSAEVSNMEYMHLG
I*YIPLVCVGGREEEY*PFLYIYTSKTFKYLN*Q
LHVS*LCMSIGCAGVIFSLFD*GYKI*RPV*LS
*SSLASFDLVSAYLNFYVPMLLCCSQLPHVICR
FLPPHFGSVCLVHLEQLFSLVTNSYFLEFRHHLF
LWEVI*FTTAFSDIPTFLCAPIALCIPLLPLQF
TLYWNEQFTCLPQVCKHNLI*NELQ*SSVTT

Sequence NM_201281

TGCACTCTGGGGGAACATGGCCGCTTCCGGTCTCCCTCCCGGGCCGGCGCTGGCCTGACTGCGGCCCCGGTCCGTAGCACTCCGCCCTCCGCTTCTCCCG
CCCTGTAGCCGCGAAGACTGCTTCAGCCTTTCCCTGTGCTGCCCCTGCCGCGCGATGGAGAAGAGCTCGAGCTGCGAGAGTCTTGGCTCCCAGCCGGCGG
CGGCTCGGCCGCCCAGCGTGGACTCCTTGTCCAGTTAATGTGTTAAGAGCCATTGACATTTGAAGATCATCAGAAGTGAAGATAAAACATCTCAAAAATT
ATAATTGCCTCCACTTCTCATTCAGAGAATTCAGTGCATACAAAATCAGCTTCTGTTGTATCATCAGATTCCATTTCAACTTCTGCCGACAACTTTTCTC
CTGATTTGAGGGTCCTGAGGGAGTCTAACAAGTTAGCAGAAATGGAAGAACCACCCTTGCTTCCAGGAGAAAATATTAAAGACATGGCCAAAGATGTAAC
TTATATATGTCCATTCACTGGCGCTGTACGAGGAACTCTGACTGTCACGAATTATAGGTTATATTTCAAAAGCATGGAACGGGATCCCCCATTTGTTTTA
GATGCTTCCCTTGGTGTGATAAATAGAGTAGAAAAAATTGGTGGTGCTTCTAGTCGAGGTGAAAATTCTTATGGACTAGAAACTGTGTGTAAGGATATTA
GGAATTTACGATTTGCTCATAAACCTGAGGGGCGGACAAGAAGATCCATATTTGAGAATCTAATGAAATATGCATTTCCTGTCTCTAATAACCTGCCTCT
TTTTGCTTTTGAATACAAAGAAGTATTCCCTGAAAATGGGTGGAAGCTATATGACCCTCTTTTAGAGTATAGAAGGCAGGGAATTCCAAATGAAAGCTGG
AGAATAACAAAGATAAATGAACGATATGAACTTTGTGATACATACCCTGCCCTCCTGGTTGTGCCAGCAAATATTCCTGATGAAGAATTAAAGAGAGTGG
CATCCTTCAGATCAAGAGGCCGTATCCCAGTTTTATCATGGATTCATCCTGAAAGTCAAGCCACAATCACTCGGTGTAGCCAGCCCATGGTTGGAGTGAG
TGGAAAGCGAAGCAAAGAAGATGAAAAATACCTTCAAGCTATCATGGATTCCAATGCCCAGTCTCACAAAATCTTTATATTTGATGCCCGGCCAAGTGTT
AATGCTGTTGCCAACAAGGCAAAGGGTGGAGGTTATGAAAGTGAAGATGCCTATCAAAATGCTGAACTAGTTTTCCTGGATATCCACAATATTCATGTTA
TGAGAGAATCATTACGAAAACTTAAGGAGATTGTGTACCCCAACATTGAGGAAACCCACTGGTTGTCTAACTTGGAATCTACTCATTGGCTAGAACATAT
TAAGCTTATTCTTGCAGGGGCTCTTAGGATTGCTGACAAGGTAGAGTCAGGGAAGACGTCTGTGGTAGTGCATTGCAGTGATGGTTGGGATCGCACAGCT
CAGCTCACTTCCCTTGCCATGCTCATGTTGGATGGATACTATCGAACCATCCGAGGATTTGAAGTCCTTGTGGAGAAAGAATGGCTAAGTTTTGGACATC
GATTTCAACTAAGAGTTGGCCATGGAGATAAGAACCATGCAGATGCAGACAGATCGCCTGTTTTTCTTCAATTTATTGACTGTGTCTGGCAGATGACAAG
ACAGTTTCCTACCGCATTTGAATTCAATGAGTATTTTCTCATTACCATTTTGGACCACCTATACAGCTGCTTATTCGGAACATTCCTCTGTAATAGTGAA
CAACAGAGAGGAAAAGAGAATCTTCCTAAAAGGACTGTGTCACTGTGGTCTTACATAAACAGCCAGCTGGAAGACTTCACTAATCCTCTCTATGGGAGCT
ATTCCAATCATGTCCTTTATCCAGTAGCCAGCATGCGCCACCTAGAGCTCTGGGTGGGATATTACATAAGGTGGAATCCACGGATGAAACCACAGGAACC
TATTCACAACAGATACAAAGAACTTCTTGCTAAACGAGCAGAGCTTCAGAAAAAAGTAGAGGAACTACAGAGAGAGATTTCTAACCGATCAACCTCATCC
TCAGAGAGAGCCAGCTCTCCTGCACAGTGTGTCACTCCTGTCCAAACTGTTGTATAAAGGACTGTAAGATCAGGGGCATCATTGCTATACACTCTTGATT
ACACTGGCAGCTCTATGAGTAGAAAGTCTTCGGAATTTAGAACCCATCTATGAGAGAAAGTTCAGTCACTTTATTTATTTTAAATCTCTCTAGGATGAGT
TTAGAACTGTAGCAGTGCAGGTGGCTTAAGTGAAGTAACTCCATATGTAATTACATGATTATGATACTAATCTTTTAAGTATCCAAAGAATATTAAAATA
CTTCAATCCTGGATTCACAGTGGGAACAAGTTTCTATTAAAAGGCAAATGCTGTTACAAATTTTTGGCATCTGGTAATATTAAAACCATTTTAGAAATAC
ACTCTGTGCTCACTGTGCAGAGGAACATCAGTTTTCAAACCAACACTGAAATTCTGTGGCATCACATATATTGGGCCTTGATGTCATGACAGATCAAAAT
CATTTGATATCCCTTTCTCCATTCTAGGTTTTTCTTTTTTTCAGTAACTGATTTACCTTGATCACTTTTCAACTTCCATATTCTTCATATAGTAAAAGGC
AAAGTGTTGAAGATACTACGGTGTGGTAGTAGTTGAAAATTATTGCCGTCATTATTTACATACTTAAGACATATTAGCAAGTTGATCCAAAATGGGAGGC
CTTATAGATGTGCTTGGGGGAAAATGAAGGGGAGAAAGTAGCCATACAGGAGTTCAAAGAATTCCATGCCCTTCAGATTAGCCCAATTACCAGAAACATC
ATGAAAGATATTTTAAAAACTAATTATTTACTACAGTGTATTTCACTTGTCTTGTGTGTCTGAACACACAGAAGCTAATTAGCAAGTTTTTAAGAAGTAT
TTAAAAATCTTACTAGGATTGACATTTTTTCTGAATTCTGTATAAATAGCTTATAGTGAGAAGTACTGTGCTCAAATTTTACATTTTTTTCCTTTGCAAA
TTCTGTAATTTCACTCAACGATTAAGTCTACCAAAGAACACACTGCATGTAAAAGATGTATTACAATCTCAAAGCCAGTAAAAGAAATCTTGCTTCACTG
TTCACCTGCTACAAGTAAGAGTTTGGTGCTGGTAGAAACATTTGACTCTGATGTCTATTTTATTCTACATAAGAGCCATATGTAATGTACTGTAACAAAG
GAGCTTCTTGTCCCCTTGGTCTTTTAATTAAAAGAAATTCCAACTGACTTTTAAACTTTGTTCTTGTCCAAAGTTGCCATTTCTTTTTTTTCCCCAGAAA
TATTTGGAAATTATTGGAGGAATATGCACCCCAGATGAAAATGTTCAGTTTGTACCCATTTTTCCTTAACCAACACCCAAATCAAACAATTAAAATATAC
AGTGTTTTTCCACTCACTAATTCACTATACAGAGAGTCTGAACCTTAGCCTCCCTCTTGGTCTTGCAGTGAGGAAGTTTCTATTAGTATATCCAATTTAG
CAAAATTGGTACCAAAATGATTTCTTTGGTAATTGTGTGAAATATAAGCTTTTTAACAGGGCATTTAAGTGGCTAGCAAATCAGTAATTAAAAATTAAGC
TTTCTACTCCAAGTATTTCACAAACGCATCTGCCATTTTCCTCATTTAAACCTTGGTTATCTTGGCCTGATACCACATAAAAGAATGTAGAATGGCTGAA
GAGATCAAGAATTTAAAGCTTCTAGTCTTAACATACTTGCATCCACTTCAAATTCAAATCAAAAGCCAGGGAAATCTAAGTGCAACCCTACCACTTCTCT
GCTGAGAACCTTCCAGTGGTTCCCCTCACCTTCTGCAGAAGTCTCCAATATGGAGTACATGCACTTGGGCATTTAATATATACCACTGGTGTGTGTGGGA
GGGAGGGAGGAGGAATACTAGCCCTTTTTATATATTTACACAAGCAAAACTTTTAAATATTTGAATTGACAGTTACATGTTTCATAACTTTGTATGTCTA
TTGGTTGTGCAGGTGTAATTTTTTCCCTTTTTGATTAGGGTTACAAAATTTAGAGACCAGTATGATTAAGTTGAAGCTCCTTAGCCTCCTTCGACCTAGT
CTCTGCATACCTCAACTTTTACGTACCAATGCTACTCTGCTGTTCACAATTGCCTCATGTAATCTGCAGATTCCTGCCTCCCCACTTTGGTTCAGTCTGT
CTTGTGCACCTGGAACAACTGTTCTCCCTTGTGACTAATTCCTATTTTCTAGAGTTTAGGCATCATCTCTTCCTTTGGGAAGTTATCTGATTCACGACTG
CCTTCTCTGACATCCCCACCTTCCTCTGTGCCCCCATAGCACTGTGTATACCGCTACTACCACTGCAATTCACATTATATTGGAATGAACAATTCACATG
TCTACCACAAGTCTGTAAACATAACCTTATTTGAAATGAATTGCAATAAAGCTCTGTTACAACGT
  • refseq_MTMR2.F1 (forward primer)
  • refseq_MTMR2.R1 (reverse primer)
  • Single exon skipping

Frame 0

CTLGEHGRFRSPSRAGAGLTAAPVRSTPPSASP
AL*PRRLLQPFPVLPLPRDGEELELRESWLPAGG
GSAAQRGLLVQLMC*EPLTFEDHQK*R*NISKI
IIASTSHSENSVHTKSASVVSSDSISTSADNFS
PDLRVLRESNKLAEMEEPPLLPGENIKDMAKDVT
YICPFTGAVRGTLTVTNYRLYFKSMERDPPFVL
DASLGVINRVEKIGGASSRGENSYGLETVCKDI
RNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL
FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESW
RITKINERYELCDTYPALLVVPANIPDEELKRV
ASFRSRGRIPVLSWIHPESQATITRCSQPMVGVS
GKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSV
NAVANKAKGGGYESEDAYQNAELVFLDIHNIHV
MRESLRKLKEIVYPNIEETHWLSNLESTHWLEHI
KLILAGALRIADKVESGKTSVVVHCSDGWDRTA
QLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGH
RFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR
QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSE
QQRGKENLPKRTVSLWSYINSQLEDFTNPLYGS
YSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEP
IHNRYKELLAKRAELQKKVEELQREISNRSTSS
SERASSPAQCVTPVQTVV*RTVRSGASLLYTLD
YTGSSMSRKSSEFRTHL*EKVQSLYLF*ISLG*V
*NCSSAGGLSEVTPYVIT*L*Y*SFKYPKNIKI
LQSWIHSGNKFLLKGKCCYKFLASGNIKTILEI
HSVLTVQRNISFQTNTEILWHHIYWALMS*QIKI
I*YPFLHSRFFFFSVTDLP*SLFNFHILHIVKG
KVLKILRCGSS*KLLPSLFTYLRHISKLIQNGR
PYRCAWGKMKGRK*PYRSSKNSMPFRLAQLPETS
*KIF*KLIIYYSVFHLSCVSEHTEAN*QVFKKY
LKILLGLTFFLNSV*IAYSEKYCAQILHFFPLQ
IL*FHSTIKSTKEHTACKRCITISKPVKEILLHC
SPATSKSLVLVETFDSDVYFILHKSHM*CTVTK
ELLVPLVF*LKEIPTDF*TLFLSKVAISFFSPE
IFGNYWRNMHPR*KCSVCTHFSLTNTQIKQLKYT
VFFHSLIHYTESLNLSLPLGLAVRKFLLVYPI*
QNWYQNDFFGNCVKYKLFNRAFKWLANQ*LKIK
LSTPSISQTHLPFSSFKPWLSWPDTT*KNVEWLK
RSRI*SF*S*HTCIHFKFKSKAREI*VQPYHFS
AENLPVVPLTFCRSLQYGVHALGHLIYTTGVCG
REGGGILALFIYLHKQNF*IFELTVTCFITLYVY
WLCRCNFFPF*LGLQNLETSMIKLKLLSLLRPS
LCIPQLLRTNATLLFTIASCNLQIPASPLWFSL
SCAPGTTVLPCD*FLFSRV*ASSLPLGSYLIHDC
LL*HPHLPLCPHSTVYTATTTAIHIILE*TIHM
STTSL*T*PYLK*IAIKLCYN

Frame 1

ALWGNMAASGLPPGPALA*LRPRSVALRPPLLP
PCSREDCFSLSLCCPCRAMEKSSSCESLGSQPA
AARPPSVDSLSS*CVKSH*HLKIIRSEDKTSQKL
*LPPLLIQRIQCIQNQLLLYHQIPFQLLPTTFL
LI*GS*GSLTS*QKWKNHPCFQEKILKTWPKM*
LIYVHSLALYEEL*LSRIIGYISKAWNGIPHLF*
MLPLV**IE*KKLVVLLVEVKILMD*KLCVRIL
GIYDLLINLRGGQEDPYLRI**NMHFLSLITCL
FLLLNTKKYSLKMGGSYMTLF*SIEGREFQMKAG
E*QR*MNDMNFVIHTLPSWLCQQIFLMKN*REW
HPSDQEAVSQFYHGFILKVKPQSLGVASPWLE*
VESEAKKMKNTFKLSWIPMPSLTKSLYLMPGQVL
MLLPTRQRVEVMKVKMPIKMLN*FSWISTIFML
*ENHYENLRRLCTPTLRKPTGCLTWNLLIG*NI
LSLFLQGLLGLLTR*SQGRRLW*CIAVMVGIAQL
SSLPLPCSCWMDTIEPSEDLKSLWRKNG*VLDI
DFN*ELAMEIRTMQMQTDRLFFFNLLTVSGR*Q
DSFLPHLNSMSIFSLPFWTTYTAAYSEHSSVIVN
NREEKRIFLKGLCHCGLT*TASWKTSLILSMGA
IPIMSFIQ*PACAT*SSGWDIT*GGIHG*NHRN
LFTTDTKNFLLNEQSFRKK*RNYRERFLTDQPHP
QREPALLHSVSLLSKLLYKGL*DQGHHCYTLLI
TLAAL*VESLRNLEPIYERKFSHFIYFKSL*DE
FRTVAVQVA*VK*LHM*LHDYDTNLLSIQRILKY
FNPGFTVGTSFY*KANAVTNFWHLVILKPF*KY
TLCSLCRGTSVFKPTLKFCGITYIGP*CHDRSK
SFDIPFSILGFSFFQ*LIYLDHFSTSIFFI**KA
KC*RYYGVVVVENYCRHYLHT*DILAS*SKMGG
LIDVLGGK*RGESSHTGVQRIPCPSD*PNYQKH
HERYFKN*LFTTVYFTCLVCLNTQKLISKFLRSI
*KSY*D*HFF*ILYK*LIVRSTVLKFYIFFLCK
FCNFTQRLSLPKNTLHVKDVLQSQSQ*KKSCFT
VHLLQVRVWCW*KHLTLMSILFYIRAICNVL*QR
SFLSPWSFN*KKFQLTFKLCSCPKLPFLFFPQK
YLEIIGGICTPDENVQFVPIFP*PTPKSNN*NI
QCFSTH*FTIQRV*TLASLLVLQ*GSFY*YIQFS
KIGTKMISLVIV*NISFLTGHLSG*QISN*KLS
FLLQVFHKRICHFPHLNLGYLGLIPHKRM*NG*
RDQEFKASSLNILASTSNSNQKPGKSKCNPTTSL
LRTFQWFPSPSAEVSNMEYMHLGI*YIPLVCVG
GREEEY*PFLYIYTSKTFKYLN*QLHVS*LCMS
IGCAGVIFSLFD*GYKI*RPV*LS*SSLASFDLV
SAYLNFYVPMLLCCSQLPHVICRFLPPHFGSVC
LVHLEQLFSLVTNSYFLEFRHHLFLWEVI*FTT
AFSDIPTFLCAPIALCIPLLPLQFTLYWNEQFTC
LPQVCKHNLI*NELQ*SSVTT

Frame 2

HSGGTWPLPVSLPGRRWPDCGPGP*HSALRFSR
PVAAKTASAFPCAAPAARWRRARAARVLAPSRR
RLGRPAWTPCPVNVLRAIDI*RSSEVKIKHLKN
YNCLHFSFREFSAYKISFCCIIRFHFNFCRQLFS
*FEGPEGV*QVSRNGRTTLASRRKY*RHGQRCN
LYMSIHWRCTRNSDCHEL*VIFQKHGTGSPICF
RCFPWCDK*SRKNWWCF*SR*KFLWTRNCV*GY*
EFTICS*T*GADKKIHI*ESNEICISCL**PAS
FCF*IQRSIP*KWVEAI*PSFRV*KAGNSK*KL
ENNKDK*TI*TL*YIPCPPGCASKYS**RIKESG
ILQIKRPYPSFIMDSS*KSSHNHSV*PAHGWSE
WKAKQRR*KIPSSYHGFQCPVSQNLYI*CPAKC
*CCCQQGKGWRL*K*RCLSKC*TSFPGYPQYSCY
ERIITKT*GDCVPQH*GNPLVV*LGIYSLARTY
*AYSCRGS*DC*QGRVREDVCGSALQ*WLGSHS
SAHFPCHAHVGWILSNHPRI*SPCGERMAKFWTS
ISTKSWPWR*EPCRCRQIACFSSIY*LCLADDK
TVSYRI*IQ*VFSHYHFGPPIQLLIRNIPL***
TTERKRESS*KDCVTVVLHKQPAGRLH*SSLWEL
FQSCPLSSSQHAPPRALGGILHKVESTDETTGT
YSQQIQRTSC*TSRASEKSRGTTERDF*PINLI
LRESQLSCTVCHSCPNCCIKDCKIRGIIAIHS*L
HWQLYE*KVFGI*NPSMRESSVTLFILNLSRMS
LEL*QCRWLK*SNSICNYMIMILIF*VSKEY*N
TSILDSQWEQVSIKRQMLLQIFGIW*Y*NHFRNT
LCAHCAEEHQFSNQH*NSVASHILGLDVMTDQN
HLISLSPF*VFLFFSN*FTLITFQLPYSSYSKR
QSVEDTTVW**LKIIAVIIYILKTY*QVDPKWEA
L*MCLGENEGEKVAIQEFKEFHALQISPITRNI
MKDILKTNYLLQCISLVLCV*THRS*LASF*EV
FKNLTRIDIFSEFCINSL**EVLCSNFTFFSFAN
SVISLND*VYQRTHCM*KMYYNLKASKRNLASL
FTCYK*EFGAGRNI*L*CLFYST*EPYVMYCNK
GASCPLGLLIKRNSN*LLNFVLVQSCHFFFFPRN
IWKLLEEYAPQMKMFSLYPFFLNQHPNQTIKIY
SVFPLTNSLYRESEP*PPSWSCSEEVSISISNL
AKLVPK*FLW*LCEI*AF*QGI*VASKSVIKN*A
FYSKYFTNASAIFLI*TLVILA*YHIKECRMAE
EIKNLKLLVLTYLHPLQIQIKSQGNLSATLPLL
C*EPSSGSPHLLQKSPIWSTCTWAFNIYHWCVWE
GGRRNTSPFYIFTQAKLLNI*IDSYMFHNFVCL
LVVQV*FFPFLIRVTKFRDQYD*VEAP*PPST*
SLHTSTFTYQCYSAVHNCLM*SADSCLPTLVQSV
LCTWNNCSPL*LIPIF*SLGIISSFGKLSDSRL
PSLTSPPSSVPP*HCVYRYYHCNSHYIGMNNSH
VYHKSVNITLFEMNCNKALLQR

Sequence NM_201278

TGCACTCTGGGGGAACATGGCCGCTTCCGGTCTCCCTCCCGGGCCGGCGCTGGCCTGACTGCGGCCCCGGTCCGTAGCACTCCGCCCTCCGCTTCTCCCG
CCCTGTAGCCGCGAAGACTGCTTCAGCCTTTCCCTGTGCTGCCCCTGCCGCGCGATGGAGAAGAGCTCGAGCTGCGAGAGTCTTGGCTCCCAGCCGGCGG
CGGCTCGGCCGCCCAGCGTGGACTCCTTGTCCAGTTAATGTGTTAAGAGCCATTGACATTTGAAGATCATCAGAAGTGAAGATAAAACATCTCAAAAATT
ATAATTGCCTCCACTTCTCATTCAGAGAATTCAGTGCATACAAAATCAGCTTCTGTTGTATCATCAGATTCCATTTCAACTTCTGCCGACAACTTTTCTC
CTGATTTGAGGAGGGAGTCTCGCTCTATCCCCTAGGCTGGAGTGCATTGGCGCCATCTCGGCTCATTTGCAACCTCTGTCTCCCGGGTTCAAGCGATTCT
CCTGCCTCAGCTTCCCGAGGAGCTGGGATTACAGGTCCTGAGGGAGTCTAACAAGTTAGCAGAAATGGAAGAACCACCCTTGCTTCCAGGAGAAAATATT
AAAGACATGGCCAAAGATGTAACTTATATATGTCCATTCACTGGCGCTGTACGAGGAACTCTGACTGTCACGAATTATAGGTTATATTTCAAAAGCATGG
AACGGGATCCCCCATTTGTTTTAGATGCTTCCCTTGGTGTGATAAATAGAGTAGAAAAAATTGGTGGTGCTTCTAGTCGAGGTGAAAATTCTTATGGACT
AGAAACTGTGTGTAAGGATATTAGGAATTTACGATTTGCTCATAAACCTGAGGGGCGGACAAGAAGATCCATATTTGAGAATCTAATGAAATATGCATTT
CCTGTCTCTAATAACCTGCCTCTTTTTGCTTTTGAATACAAAGAAGTATTCCCTGAAAATGGGTGGAAGCTATATGACCCTCTTTTAGAGTATAGAAGGC
AGGGAATTCCAAATGAAAGCTGGAGAATAACAAAGATAAATGAACGATATGAACTTTGTGATACATACCCTGCCCTCCTGGTTGTGCCAGCAAATATTCC
TGATGAAGAATTAAAGAGAGTGGCATCCTTCAGATCAAGAGGCCGTATCCCAGTTTTATCATGGATTCATCCTGAAAGTCAAGCCACAATCACTCGGTGT
AGCCAGCCCATGGTTGGAGTGAGTGGAAAGCGAAGCAAAGAAGATGAAAAATACCTTCAAGCTATCATGGATTCCAATGCCCAGTCTCACAAAATCTTTA
TATTTGATGCCCGGCCAAGTGTTAATGCTGTTGCCAACAAGGCAAAGGGTGGAGGTTATGAAAGTGAAGATGCCTATCAAAATGCTGAACTAGTTTTCCT
GGATATCCACAATATTCATGTTATGAGAGAATCATTACGAAAACTTAAGGAGATTGTGTACCCCAACATTGAGGAAACCCACTGGTTGTCTAACTTGGAA
TCTACTCATTGGCTAGAACATATTAAGCTTATTCTTGCAGGGGCTCTTAGGATTGCTGACAAGGTAGAGTCAGGGAAGACGTCTGTGGTAGTGCATTGCA
GTGATGGTTGGGATCGCACAGCTCAGCTCACTTCCCTTGCCATGCTCATGTTGGATGGATACTATCGAACCATCCGAGGATTTGAAGTCCTTGTGGAGAA
AGAATGGCTAAGTTTTGGACATCGATTTCAACTAAGAGTTGGCCATGGAGATAAGAACCATGCAGATGCAGACAGATCGCCTGTTTTTCTTCAATTTATT
GACTGTGTCTGGCAGATGACAAGACAGTTTCCTACCGCATTTGAATTCAATGAGTATTTTCTCATTACCATTTTGGACCACCTATACAGCTGCTTATTCG
GAACATTCCTCTGTAATAGTGAACAACAGAGAGGAAAAGAGAATCTTCCTAAAAGGACTGTGTCACTGTGGTCTTACATAAACAGCCAGCTGGAAGACTT
CACTAATCCTCTCTATGGGAGCTATTCCAATCATGTCCTTTATCCAGTAGCCAGCATGCGCCACCTAGAGCTCTGGGTGGGATATTACATAAGGTGGAAT
CCACGGATGAAACCACAGGAACCTATTCACAACAGATACAAAGAACTTCTTGCTAAACGAGCAGAGCTTCAGAAAAAAGTAGAGGAACTACAGAGAGAGA
TTTCTAACCGATCAACCTCATCCTCAGAGAGAGCCAGCTCTCCTGCACAGTGTGTCACTCCTGTCCAAACTGTTGTATAAAGGACTGTAAGATCAGGGGC
ATCATTGCTATACACTCTTGATTACACTGGCAGCTCTATGAGTAGAAAGTCTTCGGAATTTAGAACCCATCTATGAGAGAAAGTTCAGTCACTTTATTTA
TTTTAAATCTCTCTAGGATGAGTTTAGAACTGTAGCAGTGCAGGTGGCTTAAGTGAAGTAACTCCATATGTAATTACATGATTATGATACTAATCTTTTA
AGTATCCAAAGAATATTAAAATACTTCAATCCTGGATTCACAGTGGGAACAAGTTTCTATTAAAAGGCAAATGCTGTTACAAATTTTTGGCATCTGGTAA
TATTAAAACCATTTTAGAAATACACTCTGTGCTCACTGTGCAGAGGAACATCAGTTTTCAAACCAACACTGAAATTCTGTGGCATCACATATATTGGGCC
TTGATGTCATGACAGATCAAAATCATTTGATATCCCTTTCTCCATTCTAGGTTTTTCTTTTTTTCAGTAACTGATTTACCTTGATCACTTTTCAACTTCC
ATATTCTTCATATAGTAAAAGGCAAAGTGTTGAAGATACTACGGTGTGGTAGTAGTTGAAAATTATTGCCGTCATTATTTACATACTTAAGACATATTAG
CAAGTTGATCCAAAATGGGAGGCCTTATAGATGTGCTTGGGGGAAAATGAAGGGGAGAAAGTAGCCATACAGGAGTTCAAAGAATTCCATGCCCTTCAGA
TTAGCCCAATTACCAGAAACATCATGAAAGATATTTTAAAAACTAATTATTTACTACAGTGTATTTCACTTGTCTTGTGTGTCTGAACACACAGAAGCTA
ATTAGCAAGTTTTTAAGAAGTATTTAAAAATCTTACTAGGATTGACATTTTTTCTGAATTCTGTATAAATAGCTTATAGTGAGAAGTACTGTGCTCAAAT
TTTACATTTTTTTCCTTTGCAAATTCTGTAATTTCACTCAACGATTAAGTCTACCAAAGAACACACTGCATGTAAAAGATGTATTACAATCTCAAAGCCA
GTAAAAGAAATCTTGCTTCACTGTTCACCTGCTACAAGTAAGAGTTTGGTGCTGGTAGAAACATTTGACTCTGATGTCTATTTTATTCTACATAAGAGCC
ATATGTAATGTACTGTAACAAAGGAGCTTCTTGTCCCCTTGGTCTTTTAATTAAAAGAAATTCCAACTGACTTTTAAACTTTGTTCTTGTCCAAAGTTGC
CATTTCTTTTTTTTCCCCAGAAATATTTGGAAATTATTGGAGGAATATGCACCCCAGATGAAAATGTTCAGTTTGTACCCATTTTTCCTTAACCAACACC
CAAATCAAACAATTAAAATATACAGTGTTTTTCCACTCACTAATTCACTATACAGAGAGTCTGAACCTTAGCCTCCCTCTTGGTCTTGCAGTGAGGAAGT
TTCTATTAGTATATCCAATTTAGCAAAATTGGTACCAAAATGATTTCTTTGGTAATTGTGTGAAATATAAGCTTTTTAACAGGGCATTTAAGTGGCTAGC
AAATCAGTAATTAAAAATTAAGCTTTCTACTCCAAGTATTTCACAAACGCATCTGCCATTTTCCTCATTTAAACCTTGGTTATCTTGGCCTGATACCACA
TAAAAGAATGTAGAATGGCTGAAGAGATCAAGAATTTAAAGCTTCTAGTCTTAACATACTTGCATCCACTTCAAATTCAAATCAAAAGCCAGGGAAATCT
AAGTGCAACCCTACCACTTCTCTGCTGAGAACCTTCCAGTGGTTCCCCTCACCTTCTGCAGAAGTCTCCAATATGGAGTACATGCACTTGGGCATTTAAT
ATATACCACTGGTGTGTGTGGGAGGGAGGGAGGAGGAATACTAGCCCTTTTTATATATTTACACAAGCAAAACTTTTAAATATTTGAATTGACAGTTACA
TGTTTCATAACTTTGTATGTCTATTGGTTGTGCAGGTGTAATTTTTTCCCTTTTTGATTAGGGTTACAAAATTTAGAGACCAGTATGATTAAGTTGAAGC
TCCTTAGCCTCCTTCGACCTAGTCTCTGCATACCTCAACTTTTACGTACCAATGCTACTCTGCTGTTCACAATTGCCTCATGTAATCTGCAGATTCCTGC
CTCCCCACTTTGGTTCAGTCTGTCTTGTGCACCTGGAACAACTGTTCTCCCTTGTGACTAATTCCTATTTTCTAGAGTTTAGGCATCATCTCTTCCTTTG
GGAAGTTATCTGATTCACGACTGCCTTCTCTGACATCCCCACCTTCCTCTGTGCCCCCATAGCACTGTGTATACCGCTACTACCACTGCAATTCACATTA
TATTGGAATGAACAATTCACATGTCTACCACAAGTCTGTAAACATAACCTTATTTGAAATGAATTGCAATAAAGCTCTGTTACAACGT
  • refseq_MTMR2.F1 (forward primer)
  • refseq_MTMR2.R1 (reverse primer)
  • Single exon skipping

Frame 0

CTLGEHGRFRSPSRAGAGLTAAPVRSTPPSASP
AL*PRRLLQPFPVLPLPRDGEELELRESWLPAGG
GSAAQRGLLVQLMC*EPLTFEDHQK*R*NISKI
IIASTSHSENSVHTKSASVVSSDSISTSADNFS
PDLRRESRSIP*AGVHWRHLGSFATSVSRVQAIL
LPQLPEELGLQVLRESNKLAEMEEPPLLPGENI
KDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSM
ERDPPFVLDASLGVINRVEKIGGASSRGENSYGL
ETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAF
PVSNNLPLFAFEYKEVFPENGWKLYDPLLEYRR
QGIPNESWRITKINERYELCDTYPALLVVPANIP
DEELKRVASFRSRGRIPVLSWIHPESQATITRC
SQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIF
IFDARPSVNAVANKAKGGGYESEDAYQNAELVFL
DIHNIHVMRESLRKLKEIVYPNIEETHWLSNLE
STHWLEHIKLILAGALRIADKVESGKTSVVVHC
SDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEK
EWLSFGHRFQLRVGHGDKNHADADRSPVFLQFI
DCVWQMTRQFPTAFEFNEYFLITILDHLYSCLF
GTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDF
TNPLYGSYSNHVLYPVASMRHLELWVGYYIRWN
PRMKPQEPIHNRYKELLAKRAELQKKVEELQRE
ISNRSTSSSERASSPAQCVTPVQTVV*RTVRSGA
SLLYTLDYTGSSMSRKSSEFRTHL*EKVQSLYL
F*ISLG*V*NCSSAGGLSEVTPYVIT*L*Y*SF
KYPKNIKILQSWIHSGNKFLLKGKCCYKFLASGN
IKTILEIHSVLTVQRNISFQTNTEILWHHIYWA
LMS*QIKII*YPFLHSRFFFFSVTDLP*SLFNF
HILHIVKGKVLKILRCGSS*KLLPSLFTYLRHIS
KLIQNGRPYRCAWGKMKGRK*PYRSSKNSMPFR
LAQLPETS*KIF*KLIIYYSVFHLSCVSEHTEA
N*QVFKKYLKILLGLTFFLNSV*IAYSEKYCAQI
LHFFPLQIL*FHSTIKSTKEHTACKRCITISKP
VKEILLHCSPATSKSLVLVETFDSDVYFILHKS
HM*CTVTKELLVPLVF*LKEIPTDF*TLFLSKVA
ISFFSPEIFGNYWRNMHPR*KCSVCTHFSLTNT
QIKQLKYTVFFHSLIHYTESLNLSLPLGLAVRK
FLLVYPI*QNWYQNDFFGNCVKYKLFNRAFKWLA
NQ*LKIKLSTPSISQTHLPFSSFKPWLSWPDTT
*KNVEWLKRSRI*SF*S*HTCIHFKFKSKAREI
*VQPYHFSAENLPVVPLTFCRSLQYGVHALGHLI
YTTGVCGREGGGILALFIYLHKQNF*IFELTVT
CFITLYVYWLCRCNFFPF*LGLQNLETSMIKLK
LLSLLRPSLCIPQLLRTNATLLFTIASCNLQIPA
SPLWFSLSCAPGTTVLPCD*FLFSRV*ASSLPL
GSYLIHDCLL*HPHLPLCPHSTVYTATTTAIHI
ILE*TIHMSTTSL*T*PYLK*IAIKLCYN

Frame 1

ALWGNMAASGLPPGPALA*LRPRSVALRPPLLP
PCSREDCFSLSLCCPCRAMEKSSSCESLGSQPA
AARPPSVDSLSS*CVKSH*HLKIIRSEDKTSQKL
*LPPLLIQRIQCIQNQLLLYHQIPFQLLPTTFL
LI*GGSLALSPRLECIGAISAHLQPLSPGFKRF
SCLSFPRSWDYRS*GSLTS*QKWKNHPCFQEKIL
KTWPKM*LIYVHSLALYEEL*LSRIIGYISKAW
NGIPHLF*MLPLV**IE*KKLVVLLVEVKILMD
*KLCVRILGIYDLLINLRGGQEDPYLRI**NMHF
LSLITCLFLLLNTKKYSLKMGGSYMTLF*SIEG
REFQMKAGE*QR*MNDMNFVIHTLPSWLCQQIF
LMKN*REWHPSDQEAVSQFYHGFILKVKPQSLGV
ASPWLE*VESEAKKMKNTFKLSWIPMPSLTKSL
YLMPGQVLMLLPTRQRVEVMKVKMPIKMLN*FS
WISTIFML*ENHYENLRRLCTPTLRKPTGCLTWN
LLIG*NILSLFLQGLLGLLTR*SQGRRLW*CIA
VMVGIAQLSSLPLPCSCWMDTIEPSEDLKSLWR
KNG*VLDIDFN*ELAMEIRTMQMQTDRLFFFNLL
TVSGR*QDSFLPHLNSMSIFSLPFWTTYTAAYS
EHSSVIVNNREEKRIFLKGLCHCGLT*TASWKT
SLILSMGAIPIMSFIQ*PACAT*SSGWDIT*GGI
HG*NHRNLFTTDTKNFLLNEQSFRKK*RNYRER
FLTDQPHPQREPALLHSVSLLSKLLYKGL*DQG
HHCYTLLITLAAL*VESLRNLEPIYERKFSHFIY
FKSL*DEFRTVAVQVA*VK*LHM*LHDYDTNLL
SIQRILKYFNPGFTVGTSFY*KANAVTNFWHLV
ILKPF*KYTLCSLCRGTSVFKPTLKFCGITYIGP
*CHDRSKSFDIPFSILGFSFFQ*LIYLDHFSTS
IFFI**KAKC*RYYGVVVVENYCRHYLHT*DIL
AS*SKMGGLIDVLGGK*RGESSHTGVQRIPCPSD
*PNYQKHHERYFKN*LFTTVYFTCLVCLNTQKL
ISKFLRSI*KSY*D*HFF*ILYK*LIVRSTVLK
FYIFFLCKFCNFTQRLSLPKNTLHVKDVLQSQSQ
*KKSCFTVHLLQVRVWCW*KHLTLMSILFYIRA
ICNVL*QRSFLSPWSFN*KKFQLTFKLCSCPKL
PFLFFPQKYLEIIGGICTPDENVQFVPIFP*PTP
KSNN*NIQCFSTH*FTIQRV*TLASLLVLQ*GS
FY*YIQFSKIGTKMISLVIV*NISFLTGHLSG*
QISN*KLSFLLQVFHKRICHFPHLNLGYLGLIPH
KRM*NG*RDQEFKASSLNILASTSNSNQKPGKS
KCNPTTSLLRTFQWFPSPSAEVSNMEYMHLGI*
YIPLVCVGGREEEY*PFLYIYTSKTFKYLN*QLH
VS*LCMSIGCAGVIFSLFD*GYKI*RPV*LS*S
SLASFDLVSAYLNFYVPMLLCCSQLPHVICRFL
PPHFGSVCLVHLEQLFSLVTNSYFLEFRHHLFLW
EVI*FTTAFSDIPTFLCAPIALCIPLLPLQFTL
YWNEQFTCLPQVCKHNLI*NELQ*SSVTT

Frame 2

HSGGTWPLPVSLPGRRWPDCGPGP*HSALRFSR
PVAAKTASAFPCAAPAARWRRARAARVLAPSRR
RLGRPAWTPCPVNVLRAIDI*RSSEVKIKHLKN
YNCLHFSFREFSAYKISFCCIIRFHFNFCRQLFS
*FEEGVSLYPLGWSALAPSRLICNLCLPGSSDS
PASASRGAGITGPEGV*QVSRNGRTTLASRRKY
*RHGQRCNLYMSIHWRCTRNSDCHEL*VIFQKHG
TGSPICFRCFPWCDK*SRKNWWCF*SR*KFLWT
RNCV*GY*EFTICS*T*GADKKIHI*ESNEICI
SCL**PASFCF*IQRSIP*KWVEAI*PSFRV*KA
GNSK*KLENNKDK*TI*TL*YIPCPPGCASKYS
**RIKESGILQIKRPYPSFIMDSS*KSSHNHSV
*PAHGWSEWKAKQRR*KIPSSYHGFQCPVSQNLY
I*CPAKC*CCCQQGKGWRL*K*RCLSKC*TSFP
GYPQYSCYERIITKT*GDCVPQH*GNPLVV*LG
IYSLARTY*AYSCRGS*DC*QGRVREDVCGSALQ
*WLGSHSSAHFPCHAHVGWILSNHPRI*SPCGE
RMAKFWTSISTKSWPWR*EPCRCRQIACFSSIY
*LCLADDKTVSYRI*IQ*VFSHYHFGPPIQLLIR
NIPL***TTERKRESS*KDCVTVVLHKQPAGRL
H*SSLWELFQSCPLSSSQHAPPRALGGILHKVE
STDETTGTYSQQIQRTSC*TSRASEKSRGTTERD
F*PINLILRESQLSCTVCHSCPNCCIKDCKIRG
IIAIHS*LHWQLYE*KVFGI*NPSMRESSVTLF
ILNLSRMSLEL*QCRWLK*SNSICNYMIMILIF*
VSKEY*NTSILDSQWEQVSIKRQMLLQIFGIW*
Y*NHFRNTLCAHCAEEHQFSNQH*NSVASHILG
LDVMTDQNHLISLSPF*VFLFFSN*FTLITFQLP
YSSYSKRQSVEDTTVW**LKIIAVIIYILKTY*
QVDPKWEAL*MCLGENEGEKVAIQEFKEFHALQ
ISPITRNIMKDILKTNYLLQCISLVLCV*THRS*
LASF*EVFKNLTRIDIFSEFCINSL**EVLCSN
FTFFSFANSVISLND*VYQRTHCM*KMYYNLKA
SKRNLASLFTCYK*EFGAGRNI*L*CLFYST*EP
YVMYCNKGASCPLGLLIKRNSN*LLNFVLVQSC
HFFFFPRNIWKLLEEYAPQMKMFSLYPFFLNQH
PNQTIKIYSVFPLTNSLYRESEP*PPSWSCSEEV
SISISNLAKLVPK*FLW*LCEI*AF*QGI*VAS
KSVIKN*AFYSKYFTNASAIFLI*TLVILA*YH
IKECRMAEEIKNLKLLVLTYLHPLQIQIKSQGNL
SATLPLLC*EPSSGSPHLLQKSPIWSTCTWAFN
IYHWCVWEGGRRNTSPFYIFTQAKLLNI*IDSY
MFHNFVCLLVVQV*FFPFLIRVTKFRDQYD*VEA
P*PPST*SLHTSTFTYQCYSAVHNCLM*SADSC
LPTLVQSVLCTWNNCSPL*LIPIF*SLGIISSF
GKLSDSRLPSLTSPPSSVPP*HCVYRYYHCNSHY
IGMNNSHVYHKSVNITLFEMNCNKALLQR

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