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Sequences

Sequence NM_004954

TCCTGGAATTGCACGCGCTTCCTGACCACCAGGCTCTGGCCCTTGAGAAGCCAGCGGGGCTTTGTCCCTGTTGCTCTCCTTGCCAAACCCAGTCTCTCTG
CTAGTGGTGGTTTCGGTTGCGACACCGTCCAGGTTCCCAGGCAGGAACCGCTCGGCCTGGCTGCTTAGCTACTTTTCACTGAGGAGGTGGTGGAAGGTGT
CGCCTGCTCTGGCTGAGTAAGGGTGGCTGGCTGAGCCGGCAGCCCCCGCCCTAGGCCTGGCTCTTCCCGGCCTCTGTACTTTGCCCTCGCTGCCTGACAG
GTTCTGCTGTGGGCTCTGCTGAATGGAAGTCGCTGGTAGTCCTTTTCCCTTTCTCCAGTCGGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAA
GTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTT
GCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTAT
TCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTA
CGCTAGTGGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAG
TACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCA
ATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGT
GGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGG
GGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAA
TCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCT
GATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAG
AGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCA
GCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGC
AGAAAATAAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAG
ACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCA
TCCAGAATGGCAAAGACAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAA
CTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCT
CCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGGAACCTGAATGAACCTGAAAGCA
AAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTT
CACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCAT
GAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACG
GGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGG
GGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTCCCCTGCTGGCAC
TTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGG
TGGATGGGGGGGCAGGGCTCCCCCTCGGTACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAGAAAAAA
  • refseq_MARK2.F4 (forward primer)
  • refseq_MARK2.R4 (reverse primer)
  • Single exon skipping

Frame 0

SWNCTRFLTTRLWPLRSQRGFVPVALLAKPSLS
ASGGFGCDTVQVPRQEPLGLAA*LLFTEEVVEGV
ACSG*VRVAG*AGSPRPRPGSSRPLYFALAA*Q
VLLWALLNGSRW*SFSLSPVGPPWDTLTPSPAV
SPT*FGAATQPPLLMSSPTLETTGSSRPLARVIL
PR*SWPDTS*LGKR*L*RSLTRLN*TPPASRNY
SAK*E**RF*IIPT*LNYLK*LRLRKRSTLSWS
TLVAERYLIT*WLMAG*KKKRLEPNSAR*CLLCS
TVTRSLLSIET*RQKTCSWMLI*TSRLQTLASA
MNSPLGTSWTPSVAVPLMLPQNSSRAKNMMDPR
WMCGA*ELSSIHWSADPCLLMDRTSRSCGNGY*G
ENTVFHSTCPRTVKTCLRNFSFLIPAREAL*SK
S*KIDG*MWVTKMMN*SLTWSHSLTTRTPGGQS
*WCPWVIHGKRSRTRWWARDTTR*WPPICSWATR
APSWKATPSP*NPGLQLI*PIAAPHPHPTRYSA
ACRPIPSSGASATRLVLPFPPLILTLRRLRVTT
QKISGLRRTGSQGGKPAAQPRCLPAPCPVWRGRR
PPQPPPRTASSPPAQIEAGIPHFWSGPASARPP
SRMAKTAQPPSVSLLPPHPPTTSAAVVEPQTEL
TSPGVCPAEAPSMLGSSDRCGTSRICPTV*PQPL
PLATARAGGGPLGASSASSPPSLYAGT*MNLKA
KTEWRRSDLTWWAVAATTKKRKNFGRPSPAPSA
SRGV*RPRAPWSPTR*CGRSARCWTRTAARASCM
RSTCCCACTARRATRTSCSGRWRCANCRGSLST
GFDLSGYRAPPWPSKTLPPK*PTS*SFNRLPGA
GAAGAGQLDGLPAAAPPHLGETAAMDWCVSPAGT
SPLPGPSQFSPTFTPAQRFPLLLSPTGGKGRGG
WMGGQGSPSVLRLHRVFRLNQEIFYYQKEK

Frame 1

PGIARAS*PPGSGP*EASGALSLLLSLPNPVSL
LVVVSVATPSRFPGRNRSAWLLSYFSLRRWWKV
SPALAE*GWLAEPAAPALGLALPGLCTLPSLPDR
FCCGLC*MEVAGSPFPFLQSAHLGTP*LQAQQ*
VQHDSGPQLSHLC**AAPHWKLPAPQDHWQG*F
CQGEVGPTHPDWERGSCEDH*QDSTELLQPPETI
PRSKNNEGFESSQHS*II*SD*D*ENALPCHGV
R*WRRGI*LPSGSWQDERKRGSSQIPPDSVCCA
VLSPEVYCP*RLKGRKPALGC*YEHQDCRLWLQQ
*IHLWEQAGHLLWQSPLCCPRTLPGQKI*WTRG
GCVEPRSYPLYTGQRIPAF*WTEPQGAAGTGTE
GKIPYSILHVHGL*KPA*EISHS*SQQERHFRAN
HERSMDECGSRR**TKALRGATP*LQGPPADRA
DGVHGLYTGRDPGLAGGPEIQRGDGHLSAPGLQ
ELRAGRRHHHPETPAFS*SDQ*QRPIPIPQGTAQ
RVGQSQAAALQRPGWSCHSHL*FLL*EDSE*QR
RK*AA*GGPGVRAESQQHSQGACQPPARSGEEE
DHPNPLHEQRPLHQHKSKQEFPTFGAGQPRPGLH
PEWQRQHSPPACPCCLPIRPQHQQQWWSPRPN*
LPPGCVQPKHLPCWAAPTGAGPAEFALRCDPSL
SLWPQPGPAGGLWEHLQQVHLQVCTQEPE*T*KQ
RPSGDAQTSRGGQWRQRQRKGRISGGQAPLPPL
HVEYEDHELHGAQRDDAGDPQGAGREQLPERAA
*EVHAAVHARHAGPRGLRAVGDGGVQTAAALSQR
GSI*ADIGHLHGLQKHCLQNSQRAEALTGCQER
GRRGRASWTGCRPLRRPTWARLQRWIGVSPLLA
LLPSLALLSFLPHSPLPRDSPFSSPLLEAKEGEG
GWGGRAPPRYCGCTEYFA*TKKFFITKKKK

Frame 2

LELHALPDHQALALEKPAGLCPCCSPCQTQSLC
*WWFRLRHRPGSQAGTARPGCLATFH*GGGGRC
RLLWLSKGGWLSRQPPP*AWLFPASVLCPRCLT
GSAVGSAEWKSLVVLFPFSSRPTLGHLDSKPSSK
SNMIRGRNSATSADEQPHIGNYRLLKTIGKGNF
AKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL
FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEY
ASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ
YCHQKFIVHRDLKAENLLLDADMNIKIADFGFS
NEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV
DVWSLGVILYTLVSGSLPFDGQNLKELRERVLR
GKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ
IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTEL
MVSMGYTREEIQDSLVGQRYNEVMATYLLLGYK
SSELEGDTITLKPRPSADLTNSSAPSPSHKVQR
SVSANPKQRRFSDQAGPAIPTSNSYSKKTQSNNA
ENKRPEEDRESGRKASSTAKVPASPLPGLERKK
TTPTPSTNSVLSTSTNRSRNSPLLERASLGQAS
IQNGKDSTAPQRVPVASPSAHNISSSGGAPDRTN
FPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPAS
PSGHSQGRRGASGSIFSKFTSKFVRRNLNEPES
KDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRF
TWSMKTTSSMEPNEMMREIRKVLDANSCQSELH
EKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLN
GVRFKRISGTSMAFKNIASKIANELKL*QAARSG
GGGGGPAGRAAGRCAAPPGRDCSDGLVCLPCWH
FSPPWPFSVFSHIHPCPEIPPSPLPYWRQRKGR
VDGGAGLPLGTAVAQSISPKPRNFLLPKRK

Sequence NM_001039468

AAGCCCCGCCCGGCCGGGCTCCGCGCCTTCCCTTCCCTCCCTTCCTCCAAGCTTCTCGGTTCCCTCCCCCGAGATACCGGCGCCATGTCCAGCGCTCGGA
CCCCCCTACCCACGCTGAACGAGAGGGACACGGAGCAGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAA
CTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACAC
ATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGG
TTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGA
TTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTTATTGTC
CATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTCACCTTTGGGAACAAGC
TGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTAT
CCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTAC
ATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATG
TGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACG
GGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACC
ATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGC
GGCGCTTCAGCGACCAGGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGA
CCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCCTCCACGAAC
AGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAGAATGGCAAAGACAGCACAG
CCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGTGTGTCCAGCCG
AAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGG
CGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGAC
CTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAG
CTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATG
CACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGG
GCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGG
ACGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCA
GTTTTCTCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCC
TCGGTACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAGAAAAAA
  • refseq_MARK2.F4 (forward primer)
  • refseq_MARK2.R4 (reverse primer)
  • Single exon skipping

Frame 0

KPRPAGLRAFPSLPSSKLLGSLPRDTGAMSSAR
TPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRN
SATSADEQPHIGNYRLLKTIGKGNFAKVKLARH
ILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMK
VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFD
YLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIV
HRDLKAENLLLDADMNIKIADFGFSNEFTFGNK
LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI
LYTLVSGSLPFDGQNLKELRERVLRGKYRIPFY
MSTDCENLLKKFLILNPSKRGTLEQIMKDRWMN
VGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTR
EEIQDSLVGQRYNEVMATYLLLGYKSSELEGDT
ITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQ
RRFSDQAGPAIPTSNSYSKKTQSNNAENKRPEED
RESGRKASSTAKVPASPLPGLERKKTTPTPSTN
SVLSTSTNRSRNSPLLERASLGQASIQNGKDST
APQRVPVASPSAHNISSSGGAPDRTNFPRGVSSR
STFHAGQLRQVRDQQNLPYGVTPASPSGHSQGR
RGASGSIFSKFTSKFVRRNLNEPESKDRVETLR
PHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTS
SMEPNEMMREIRKVLDANSCQSELHEKYMLLCM
HGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRIS
GTSMAFKNIASKIANELKL*QAARSGGGGGGPAG
RAAGRCAAPPGRDCSDGLVCLPCWHFSPPWPFS
VFSHIHPCPEIPPSPLPYWRQRKGRVDGGAGLP
LGTAVAQSISPKPRNFLLPKRK

Frame 1

SPARPGSAPSLPSLPPSFSVPSPEIPAPCPALG
PPYPR*TRGTRSSPPWDTLTPSPAVSPT*FGAA
TQPPLLMSSPTLETTGSSRPLARVILPR*SWPDT
S*LGKR*L*RSLTRLN*TPPASRNYSAK*E**R
F*IIPT*LNYLK*LRLRKRSTLSWSTLVAERYL
IT*WLMAG*KKKRLEPNSAR*CLLCSTVTRSLLS
IET*RQKTCSWMLI*TSRLQTLASAMNSPLGTS
WTPSVAVPLMLPQNSSRAKNMMDPRWMCGA*EL
SSIHWSADPCLLMDRTSRSCGNGY*GENTVFHST
CPRTVKTCLRNFSFLIPAREAL*SKS*KIDG*M
WVTKMMN*SLTWSHSLTTRTPGGQS*WCPWVIH
GKRSRTRWWARDTTR*WPPICSWATRAPSWKATP
SP*NPGLQLI*PIAAPHPHPTRYSAACRPIPSS
GASATRLVLPFPPLILTLRRLRVTTQKISGLRR
TGSQGGKPAAQPRCLPAPCPVWRGRRPPQPPPRT
ASSPPAQIEAGIPHFWSGPASARPPSRMAKTAQ
PPSVSLLPPHPPTTSAAVVEPQTELTSPGVCPA
EAPSMLGSSDRCGTSRICPTV*PQPLPLATARAG
GGPLGASSASSPPSLYAGT*MNLKAKTEWRRSD
LTWWAVAATTKKRKNFGRPSPAPSASRGV*RPR
APWSPTR*CGRSARCWTRTAARASCMRSTCCCAC
TARRATRTSCSGRWRCANCRGSLSTGFDLSGYR
APPWPSKTLPPK*PTS*SFNRLPGAGAAGAGQL
DGLPAAAPPHLGETAAMDWCVSPAGTSPLPGPSQ
FSPTFTPAQRFPLLLSPTGGKGRGGWMGGQGSP
SVLRLHRVFRLNQEIFYYQKEK

Frame 2

APPGRAPRLPFPPFLQASRFPPPRYRRHVQRSD
PPTHAEREGHGAAHLGTP*LQAQQ*VQHDSGPQ
LSHLC**AAPHWKLPAPQDHWQG*FCQGEVGPT
HPDWERGSCEDH*QDSTELLQPPETIPRSKNNEG
FESSQHS*II*SD*D*ENALPCHGVR*WRRGI*
LPSGSWQDERKRGSSQIPPDSVCCAVLSPEVYC
P*RLKGRKPALGC*YEHQDCRLWLQQ*IHLWEQA
GHLLWQSPLCCPRTLPGQKI*WTRGGCVEPRSY
PLYTGQRIPAF*WTEPQGAAGTGTEGKIPYSIL
HVHGL*KPA*EISHS*SQQERHFRANHERSMDEC
GSRR**TKALRGATP*LQGPPADRADGVHGLYT
GRDPGLAGGPEIQRGDGHLSAPGLQELRAGRRH
HHPETPAFS*SDQ*QRPIPIPQGTAQRVGQSQAA
ALQRPGWSCHSHL*FLL*EDSE*QRRK*AA*GG
PGVRAESQQHSQGACQPPARSGEEEDHPNPLHE
QRPLHQHKSKQEFPTFGAGQPRPGLHPEWQRQHS
PPACPCCLPIRPQHQQQWWSPRPN*LPPGCVQP
KHLPCWAAPTGAGPAEFALRCDPSLSLWPQPGP
AGGLWEHLQQVHLQVCTQEPE*T*KQRPSGDAQT
SRGGQWRQRQRKGRISGGQAPLPPLHVEYEDHE
LHGAQRDDAGDPQGAGREQLPERAA*EVHAAVH
ARHAGPRGLRAVGDGGVQTAAALSQRGSI*ADIG
HLHGLQKHCLQNSQRAEALTGCQERGRRGRASW
TGCRPLRRPTWARLQRWIGVSPLLALLPSLALL
SFLPHSPLPRDSPFSSPLLEAKEGEGGWGGRAPP
RYCGCTEYFA*TKKFFITKKKK

Sequence NM_001039469

CCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAA
ACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGA
CAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTG
ATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGG
CTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGC
TGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCA
GAACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATG
GACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCT
CATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAG
CCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACA
ACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAA
TAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCAGCTGGTCCTGCCATTCCC
ACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCA
AGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAA
TTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAGAATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCT
TCTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCACCAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTA
ACTGTGAGGTGCCGCGGCCCAG
CACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAAC
TAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCC
TCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGGTTTG
CCAGAAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATT
TCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTG
GACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGG
TGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGA
GCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGC
GATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCTTACATGTTTGTGGGGGGTGGGAGATTGTTCTCCAGCA
CCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCCTCGGTA
CTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAA
  • refseq_MARK2.F4 (forward primer)
  • refseq_MARK2.R4 (reverse primer)
  • Single exon skipping

Frame 0

PTLGHLDSKPSSKSNMIRGRNSATSADEQPHIG
NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIID
KTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEV
IETEKTLYLVMEYASGGEVFDYLVAHGRMKEKE
ARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDA
DMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAP
ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD
GQNLKELRERVLRGKYRIPFYMSTDCENLLKKFL
ILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVE
PLPDYKDPRRTELMVSMGYTREEIQDSLVGQRY
NEVMATYLLLGYKSSELEGDTITLKPRPSADLTN
SSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIP
TSNSYSKKTQSNNAENKRPEEDRESGRKASSTA
KVPASPLPGLERKKTTPTPSTNSVLSTSTNRSRN
SPLLERASLGQASIQNGKDSLTMPGSRASTASA
SAAVSAARPRQHQKSMSASVHPNKASGLPPTES
NCEVPRPS
TAPQRVPVASPSAHNISSSGGAPDRT
NFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPA
SPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRF
ARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEF
REAKPRSLRFTWSMKTTSSMEPNEMMREIRKVL
DANSCQSELHEKYMLLCMHGTPGHEDFVQWEME
VCKLPRLSLNGVRFKRISGTSMAFKNIASKIANE
LKL*QAARSGGGGGGPAGRAAGRCAAPPGRDCS
DGLVCLPCWHFSPPWPFSVFSYMFVGGGRLFSS
TPHSPLPRDSPFSSPLLEAKEGEGGWGGRAPPRY
CGCTEYFA*TKKFFITK

Frame 1

PPWDTLTPSPAVSPT*FGAATQPPLLMSSPTLE
TTGSSRPLARVILPR*SWPDTS*LGKR*L*RSL
TRLN*TPPASRNYSAK*E**RF*IIPT*LNYLK*
LRLRKRSTLSWSTLVAERYLIT*WLMAG*KKKR
LEPNSAR*CLLCSTVTRSLLSIET*RQKTCSWM
LI*TSRLQTLASAMNSPLGTSWTPSVAVPLMLPQ
NSSRAKNMMDPRWMCGA*ELSSIHWSADPCLLM
DRTSRSCGNGY*GENTVFHSTCPRTVKTCLRNF
SFLIPAREAL*SKS*KIDG*MWVTKMMN*SLTWS
HSLTTRTPGGQS*WCPWVIHGKRSRTRWWARDT
TR*WPPICSWATRAPSWKATPSP*NPGLQLI*P
IAAPHPHPTRYSAACRPIPSSGASATRQLVLPFP
PLILTLRRLRVTTQKISGLRRTGSQGGKPAAQP
RCLPAPCPVWRGRRPPQPPPRTASSPPAQIEAG
IPHFWSGPASARPPSRMAKTA*PCQGPGPPRLLL
LPQSLRPGPASTRNPCRPPCTPTRPLGCPPRRV
TVRCRGP
AQPPSVSLLPPHPPTTSAAVVEPQTE
LTSPGVCPAEAPSMLGSSDRCGTSRICPTV*PQP
LPLATARAGGGPLGASSASSPPSLYAEICLSGL
PEGT*MNLKAKTEWRRSDLTWWAVAATTKKRKN
FGRPSPAPSASRGV*RPRAPWSPTR*CGRSARCW
TRTAARASCMRSTCCCACTARRATRTSCSGRWR
CANCRGSLSTGFDLSGYRAPPWPSKTLPPK*PT
S*SFNRLPGAGAAGAGQLDGLPAAAPPHLGETAA
MDWCVSPAGTSPLPGPSQFSLTCLWGVGDCSPA
PHIHPCPEIPPSPLPYWRQRKGRVDGGAGLPLG
TAVAQSISPKPRNFLLPK

Frame 2

HLGTP*LQAQQ*VQHDSGPQLSHLC**AAPHWK
LPAPQDHWQG*FCQGEVGPTHPDWERGSCEDH*
QDSTELLQPPETIPRSKNNEGFESSQHS*II*S
D*D*ENALPCHGVR*WRRGI*LPSGSWQDERKRG
SSQIPPDSVCCAVLSPEVYCP*RLKGRKPALGC
*YEHQDCRLWLQQ*IHLWEQAGHLLWQSPLCCP
RTLPGQKI*WTRGGCVEPRSYPLYTGQRIPAF*W
TEPQGAAGTGTEGKIPYSILHVHGL*KPA*EIS
HS*SQQERHFRANHERSMDECGSRR**TKALRG
ATP*LQGPPADRADGVHGLYTGRDPGLAGGPEIQ
RGDGHLSAPGLQELRAGRRHHHPETPAFS*SDQ
*QRPIPIPQGTAQRVGQSQAAALQRPGSWSCHS
HL*FLL*EDSE*QRRK*AA*GGPGVRAESQQHSQ
GACQPPARSGEEEDHPNPLHEQRPLHQHKSKQE
FPTFGAGQPRPGLHPEWQRQPNHARVPGLHGFC
FCRSLCGPAPPAPEIHVGLRAPQQGLWAAPHGE*
L*GAAAQ
HSPPACPCCLPIRPQHQQQWWSPRPN
*LPPGCVQPKHLPCWAAPTGAGPAEFALRCDPS
LSLWPQPGPAGGLWEHLQQVHLQVCTQKSVFQVC
QKEPE*T*KQRPSGDAQTSRGGQWRQRQRKGRI
SGGQAPLPPLHVEYEDHELHGAQRDDAGDPQGA
GREQLPERAA*EVHAAVHARHAGPRGLRAVGDGG
VQTAAALSQRGSI*ADIGHLHGLQKHCLQNSQR
AEALTGCQERGRRGRASWTGCRPLRRPTWARLQ
RWIGVSPLLALLPSLALLSFLLHVCGGWEIVLQH
PTFTPAQRFPLLLSPTGGKGRGGWMGGQGSPSV
LRLHRVFRLNQEIFYYQK

Sequence NM_017490

TCCTGGAATTGCACGCGCTTCCTGACCACCAGGCTCTGGCCCTTGAGAAGCCAGCGGGGCTTTGTCCCTGTTGCTCTCCTTGCCAAACCCAGTCTCTCTG
CTAGTGGTGGTTTCGGTTGCGACACCGTCCAGGTTCCCAGGCAGGAACCGCTCGGCCTGGCTGCTTAGCTACTTTTCACTGAGGAGGTGGTGGAAGGTGT
CGCCTGCTCTGGCTGAGTAAGGGTGGCTGGCTGAGCCGGCAGCCCCCGCCCTAGGCCTGGCTCTTCCCGGCCTCTGTACTTTGCCCTCGCTGCCTGACAG
GTTCTGCTGTGGGCTCTGCTGAATGGAAGTCGCTGGTAGTCCTTTTCCCTTTCTCCAGTCGGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAA
GTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTT
GCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTAT
TCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTA
CGCTAGTGGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAG
TACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCA
ATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGT
GGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGG
GGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAA
TCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCT
GATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAG
AGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCA
GCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGC
AGAAAATAAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAG
ACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCA
TCCAGAATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTTCTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCACCAGAA
ATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTAACTGTGAGGTGCCGCGGCCCAG
CACAGCCCCCCAGCGTGTC
CCTGTTGCCT
CCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATG
CTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGG
GAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGC
AGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCA
ACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGG
CCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCC
TTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCC
GCTGCGCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCCCACAT
TCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCCTCGGTACTGCGGTT
GCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAGAAAAAA
  • refseq_MARK2.F4 (forward primer)
  • refseq_MARK2.R4 (reverse primer)
  • Single exon skipping

Frame 0

SWNCTRFLTTRLWPLRSQRGFVPVALLAKPSLS
ASGGFGCDTVQVPRQEPLGLAA*LLFTEEVVEGV
ACSG*VRVAG*AGSPRPRPGSSRPLYFALAA*Q
VLLWALLNGSRW*SFSLSPVGPPWDTLTPSPAV
SPT*FGAATQPPLLMSSPTLETTGSSRPLARVIL
PR*SWPDTS*LGKR*L*RSLTRLN*TPPASRNY
SAK*E**RF*IIPT*LNYLK*LRLRKRSTLSWS
TLVAERYLIT*WLMAG*KKKRLEPNSAR*CLLCS
TVTRSLLSIET*RQKTCSWMLI*TSRLQTLASA
MNSPLGTSWTPSVAVPLMLPQNSSRAKNMMDPR
WMCGA*ELSSIHWSADPCLLMDRTSRSCGNGY*G
ENTVFHSTCPRTVKTCLRNFSFLIPAREAL*SK
S*KIDG*MWVTKMMN*SLTWSHSLTTRTPGGQS
*WCPWVIHGKRSRTRWWARDTTR*WPPICSWATR
APSWKATPSP*NPGLQLI*PIAAPHPHPTRYSA
ACRPIPSSGASATRLVLPFPPLILTLRRLRVTT
QKISGLRRTGSQGGKPAAQPRCLPAPCPVWRGRR
PPQPPPRTASSPPAQIEAGIPHFWSGPASARPP
SRMAKTA*PCQGPGPPRLLLLPQSLRPGPASTR
NPCRPPCTPTRPLGCPPRRVTVRCRGP
AQPPSVS
LLP
PHPPTTSAAVVEPQTELTSPGVCPAEAPSM
LGSSDRCGTSRICPTV*PQPLPLATARAGGGPL
GASSASSPPSLYAGT*MNLKAKTEWRRSDLTWWA
VAATTKKRKNFGRPSPAPSASRGV*RPRAPWSP
TR*CGRSARCWTRTAARASCMRSTCCCACTARR
ATRTSCSGRWRCANCRGSLSTGFDLSGYRAPPWP
SKTLPPK*PTS*SFNRLPGAGAAGAGQLDGLPA
AAPPHLGETAAMDWCVSPAGTSPLPGPSQFSPT
FTPAQRFPLLLSPTGGKGRGGWMGGQGSPSVLRL
HRVFRLNQEIFYYQKEK

Frame 1

PGIARAS*PPGSGP*EASGALSLLLSLPNPVSL
LVVVSVATPSRFPGRNRSAWLLSYFSLRRWWKV
SPALAE*GWLAEPAAPALGLALPGLCTLPSLPDR
FCCGLC*MEVAGSPFPFLQSAHLGTP*LQAQQ*
VQHDSGPQLSHLC**AAPHWKLPAPQDHWQG*F
CQGEVGPTHPDWERGSCEDH*QDSTELLQPPETI
PRSKNNEGFESSQHS*II*SD*D*ENALPCHGV
R*WRRGI*LPSGSWQDERKRGSSQIPPDSVCCA
VLSPEVYCP*RLKGRKPALGC*YEHQDCRLWLQQ
*IHLWEQAGHLLWQSPLCCPRTLPGQKI*WTRG
GCVEPRSYPLYTGQRIPAF*WTEPQGAAGTGTE
GKIPYSILHVHGL*KPA*EISHS*SQQERHFRAN
HERSMDECGSRR**TKALRGATP*LQGPPADRA
DGVHGLYTGRDPGLAGGPEIQRGDGHLSAPGLQ
ELRAGRRHHHPETPAFS*SDQ*QRPIPIPQGTAQ
RVGQSQAAALQRPGWSCHSHL*FLL*EDSE*QR
RK*AA*GGPGVRAESQQHSQGACQPPARSGEEE
DHPNPLHEQRPLHQHKSKQEFPTFGAGQPRPGLH
PEWQRQPNHARVPGLHGFCFCRSLCGPAPPAPE
IHVGLRAPQQGLWAAPHGE*L*GAAAQ
HSPPAC
PCCL
PIRPQHQQQWWSPRPN*LPPGCVQPKHLPC
WAAPTGAGPAEFALRCDPSLSLWPQPGPAGGLW
EHLQQVHLQVCTQEPE*T*KQRPSGDAQTSRGG
QWRQRQRKGRISGGQAPLPPLHVEYEDHELHGAQ
RDDAGDPQGAGREQLPERAA*EVHAAVHARHAG
PRGLRAVGDGGVQTAAALSQRGSI*ADIGHLHG
LQKHCLQNSQRAEALTGCQERGRRGRASWTGCRP
LRRPTWARLQRWIGVSPLLALLPSLALLSFLPH
SPLPRDSPFSSPLLEAKEGEGGWGGRAPPRYCG
CTEYFA*TKKFFITKKKK

Frame 2

LELHALPDHQALALEKPAGLCPCCSPCQTQSLC
*WWFRLRHRPGSQAGTARPGCLATFH*GGGGRC
RLLWLSKGGWLSRQPPP*AWLFPASVLCPRCLT
GSAVGSAEWKSLVVLFPFSSRPTLGHLDSKPSSK
SNMIRGRNSATSADEQPHIGNYRLLKTIGKGNF
AKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL
FREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEY
ASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ
YCHQKFIVHRDLKAENLLLDADMNIKIADFGFS
NEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV
DVWSLGVILYTLVSGSLPFDGQNLKELRERVLR
GKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQ
IMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTEL
MVSMGYTREEIQDSLVGQRYNEVMATYLLLGYK
SSELEGDTITLKPRPSADLTNSSAPSPSHKVQR
SVSANPKQRRFSDQAGPAIPTSNSYSKKTQSNNA
ENKRPEEDRESGRKASSTAKVPASPLPGLERKK
TTPTPSTNSVLSTSTNRSRNSPLLERASLGQAS
IQNGKDSLTMPGSRASTASASAAVSAARPRQHQK
SMSASVHPNKASGLPPTESNCEVPRPS
TAPQRV
PVA
SPSAHNISSSGGAPDRTNFPRGVSSRSTFH
AGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASG
SIFSKFTSKFVRRNLNEPESKDRVETLRPHVVG
SGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEP
NEMMREIRKVLDANSCQSELHEKYMLLCMHGTPG
HEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMA
FKNIASKIANELKL*QAARSGGGGGGPAGRAAG
RCAAPPGRDCSDGLVCLPCWHFSPPWPFSVFSHI
HPCPEIPPSPLPYWRQRKGRVDGGAGLPLGTAV
AQSISPKPRNFLLPKRK

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