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Sequences

Sequence NM_052834

GGCGGCACCGGCACCTTGCAGTATCACTGGGGAGACGGCGGCTGTATAGCGCTTGCCGCCCCACGGATTATCCCAGCAGGATCTACGCACCCCGCATCCT CCGTAGTTCCGCCCTATCCTTGTCCTCCTTGGCTGGGGCGCCCACCGGCGGTCTGATAGGCTACATCGCGGCATGAGATGAAGCTGTGACAGGTTTGAAA ACACAAACACAATGGCAGGAAACAGCCTTGTTCTACCCATTGTTCTTTGGGGTCGAAAAGCGCCCACACATTGCATCTCAGCCGTACTTTTAACAGATGA TGGGGCCACGATCGTAACAGGATGTCACGACGGACAAATATGTCTCTGGGATCTTTCAGTAGAACTGCAAATTAATCCTCGAGCACTGTTGTTTGGTCAT ACAGCATCAATCACTTGTTTGTCTAAAGCTTGTGCTTCCAGTGACAAACAGTATATTGTGAGTGCATCTGAAAGTGGAGAGATGTGCCTCTGGGATGTGA GTGATGGCAGATGTATTGAATTTACAAAATTAGCTTGCACACATACTGGCATACAGTTCTACCAGTTCTCTGTTGGGAATCAGCGAGAAGGAAGGCTTTT ATGCCACGGACATTACCCTGAAATCCTTGTTGTGGATGCTACCAGCCTTGAAGTATTATACTCCTTAGTATCAAAGATATCACCAGACTGGATTAGCTCC ATGAGTATTATTCGATCCCACCGAACACAAGAGGACACAGTGGTAGCACTCTCGGTGACTGGCATCCTGAAGGTCTGGATTGTTACCTCGGAAATAAGTG ACATGCAGGATACTGAGCCAATATTTGAGGAGGAATCCAAACCAATTTATTGTCAGAATTGCCAAAGCATCTCTTTTTGTGCATTTACACAAAGGTCACT TTTGGTTGTGTGTTCCAAATATTGGAGGGTGTTCGATGCCGGAGACTATTCCTTGTTGTGTTCAGGTCCTAGTGAAAATGGACAGACATGGACCGGGGGG GACTTTGTCTCATCAGATAAAGTCATCATTTGGACAGAAAATGGGCAAAGTTATATTTACAAACTACCTGCCAGTTGCCTTCCAGCTAGTGATTCATTCC GCAGTGATGTGGGGAAGGCAGTTGAAAATTTAATTCCTCCTGTACAACATATCCTCTTGGATCGAAAAGATAAAGAGTTGCTAATTTGTCCTCCTGTTAC TCGGTTCTTCTATGGATGCAGAGAATATTTCCATAAACTGTTAATTCAGGGTGATTCTTCTGGAAGGTTGAATATTTGGAACATATCAGACACAGCTGAT AAACAGGGAAGTGAAGAAGGGCTGGCAATGACAACTTCTATTAGTTTGCAAGAGGCATTTGATAAACTGAATCCTTGTCCTGCTGGAATTATAGATCAGC TGAGTGTGATTCCCAATAGTAATGAACCTCTTAAAGTAACTGCAAGTGTGTACATACCAGCACATGGACGACTTGTTTGTGGTCGTGAAGATGGAAGCAT AGTTATTGTACCTGCCACACAGACGGCCATAGTACAGCTGTTGCAAGGGGAACACATGCTCAGAAGAGGTTGGCCACCTCACAGAACACTCCGTGGTCAT CGGAACAAAGTCACATGTTTGCTATATCCTCATCAGGTCTCAGCTCGGTATGATCAAAGATACCTGATATCTGGAGGTGTGGATTTTTCAGTCATAATTT GGGACATATTTTCTGGAGAAATGAAACATATCTTCTGTGTTCATGGTGGTGAGATTACTCAACTTCTAGTTCCACCTGAAAACTGTAGTGCAAGAGTACA GCACTGCATCTGCTCTGTAGCCAGTGACCACTCAGTAGGACTTCTAAGTTTGCGAGAGAAAAAATGCATAATGTTGGCATCTCGTCACCTTTTTCCTATT CAAGTAATCAAATGGAGGCCTTCTGATGATTACCTGGTGGTGGGGTGTTCAGATGGTTCTGTGTACGTCTGGCAAATGGATACTGGTGCATTGGATCGTT GTGTGATGGGGATAACAGCAGTTGAGATTCTAAACGCTTGTGATGAAGCTGTTCCTGCTGCTGTTGATTCACTTAGTCATCCAGCAGTCAACCTAAAACA AGCTATGACGAGACGTAGTCTTGCTGCTCTTAAAAATATGGCCCATCATAAGCTACAAACCCTTGCAACTAACCTCTTGGCTTCTGAGGCATCTGACAAG GGAAATTTACCTAAATATTCTCATAACTCCCTGATGGTTCAAGCAATAAAGACAAACCTAACAGACCCGGACATACATGTGCTATTCTTTGATGTGGAAG CGTTGATTATTCAACTCCTGACTGAAGAAGCCTCTAGGCCGAATACTGCTCTTATTTCCCCAGAGAATTTGCAAAAAGCATCTGGCAGTTCAGACAAAGG GGGCTCTTTTTTAACTGGAAAACGAGCAGCAGTTCTCTTCCAACAAGTGAAAGAAACGATCAAAGAGAACATCAAGGAACACCTCCTTGATGATGAAGAG GAGGATGAGGAGATAATGAGGCAGAGAAGGGAAGAAAGTGATCCTGAATATCGGTCCAGCAAATCAAAGCCATTGACCCTATTAGAATATAATTTAACTA TGGACACTGCAAAGCTGTTTATGTCCTGCCTTCACGCCTGGGGTTTGAATGAAGTACTGGATGAAGTTTGCCTGGATCGCCTTGGAATGCTGAAACCCCA CTGCACCGTATCGTTTGGCCTCTTGTCAAGAGGAGGCCATATGTCACTGATGCTGCCGGGTTATAATCAGCCTGCTTGTAAACTGTCACATGGGAAAACA GAAGTAGGAAGGAAGCTGCCAGCGTCTGAGGGAGTAGGAAAGGGAACTTACGGAGTGTCCCGTGCCGTCACCACACAGCATCTCCTGTCTATCATTTCTT TGGCAAATACTTTAATGAGTATGACCAATGCAACTTTTATTGGTGATCATATGAAGAAGGGTCCTACCAGGCCACCTAGACCAAGCACCCCAGACCTTTC TAAGGCAAGGGGTTCCCCTCCAACTTCCAGTAATATTGTGCAAGGACAGATTAAACAAGGTTGGAGTCAGTTAGCTGCTATGCACTGTGTTATGCTGCCA GACCTACTGGGATTGGATAAATTTAGGCCTCCCCTTCTGGAGATGCTGGCCCGAAGATGGCAAGATCGATGCTTGGAGGTGAGAGAAGCCGCGCAGGCCC TGCTTCTGGCGGAACTGAGAAGAATTGAGCAGGCAGGCAGGAAGGAAGCCATTGATGCCTGGGCTCCTTACTTACCTCAGTACATAGACCACGTCATATC ACCTGGAGTCACATCAGAAGCCGCGCAGACTATCACCACGGCTCCTGATGCCTCAGGGCCTGAAGCAAAAGTCCAGGAGGAAGAGCATGACCTTGTTGAC GATGACATCACCACTGGTTGCTTATCAAGTGTCCCACAAATGAAAAAAATTTCTACATCTTACGAGGAAAGACGGAAGCAAGCTACCGCTATTGTTTTAC TTGGAGTAATAGGAGCTGAATTTGGTGCTGAAATTGAACCTCCTAAACTATTGACCAGACCTCGAAGCTCTAGCCAAATTCCTGAGGGATTCGGGTTGAC TAGTGGTGGATCCAACTACTCGCTGGCCAGACATACTTGCAAGGCACTGACGTTTCTTCTGCTACAGCCTCCAAGCCCCAAACTTCCTCCACACAGCACT ATCCGAAGAACAGCCATTGATCTGATTGGACGTGGGTTCACTGTTTGGGAGCCTTACATGGATGTGTCCGCTGTTCTGATGGGGCTTCTCGAACTTTGTG CCGATGCCGAGAAACAACTTGCCAACATCACAATGGGGTTGCCTCTGAGCCCAGCAGCTGACTCGGCCCGCTCTGCGAGGCATGCCCTCTCGCTCATTGC CACCGCCAGACCACCCGCCTTCATCACCACCATAGCCAAAGAGGTACACAGACATACGGCTCTTGCAGCAAATACCCAATCACAGCAGAATATGCACACA ACAACTCTTGCACGAGCTAAAGGGGAAATTTTGAGAGTCATTGAAATTCTTATTGAAAAGATGCCCACAGATGTTGTGGATCTTCTCGTGGAGGTTATGG ACATCATTATGTACTGCCTTGAAGGATCTTTAGTTAAAAAGAAAGGTCTTCAAGAATGTTTCCCAGCCATCTGCAGGTTCTACATGGTCAGCTATTATGA GCGGAATCACAGAATAGCAGTTGGAGCTCGCCATGGTTCAGTGGCCCTGTACGACATCCGGACTGGAAAATGTCAGACAATCCATGGACACAAGGGACCA ATCACTGCAGTGGCTTTTGCTCCTGATGGAAGATATCTTGCCACCTACTCAAACACTGACAGCCACATTTCTTTTTGGCAGATGAACACGTCACTGCTGG GAAGCATCGGCATGCTGAACTCGGCACCTCAGCTGCGCTGCATTAAAACCTACCAGGTGCCCCCTGTGCAGCCCGCGTCCCCCGGCTCCCACAATGCCCT CAAGCTGGCCCGGCTCATCTGGACTTCCAACCGCAACGTCATCCTCATGGCCCATGACGGGAAGGAGCACCGCTTCATGGTCTAATGCTGCTGCCTGCCG CCGTGACTGCGTTTTAGTTCTCTAAATTATCCAAGCCGATGTTGCTCTGTCCTTCCTCACACCAGATTGTTCCCAGGGGCCTGCCCACCCCAGTGCCATC CAGTGGCACGGCCGGGTCTTGTCACTTGTGCATGCTTCTCAGGGGCAGAACCCGCTCGTGCCATCTGTCGATTCAGAGGCACGCACACATGCTCTGCAGG ATGTGGCCATCCTGTCACCAGGTAGTTTTTCCCTGCCAGAGATGGCAGGGGAAAGCCAGTGGTTCCTGGGAACGCTCTTGTTGCTTGGTGCAACAGAAGC ACAAAAATCAATAAACACTGTGATTGCACTCCCAGCCCAGATCAGCATTTTTAGCCATCTCAACCGCACCTCTGAAGTGCTGCTTGAATCTGGCCGTTCT GACACTGGGTGTTGAGGTCATGTGGCAGTCCTCACGATTGAAATTATTGCCCTTTGAATTACCTAAAATATTGTTTACCAAAAAGATTCTGTGTTTACAT GTTCTTTTCTTCTGGTGATTGCTAGGAAATTACTCAATCCAATTTCCTAGGGTTTAGCTACCACCTTCTTTATCAACAGCTAACCAATTTGAGATTCATG ATTAATTATGTACACAAAAATATTTTCCTTGTAGAAAATAGTTTTCCAGACACTTAGCCTTCTGAAGTGCTCATCTCTTGCTTAAATGATAGTCTATTTA GTAGTTTAAAATAAAAATAATCACTCCCTATGATCTAGTTAATGTAATTATCCAGTCACTGTAACTAATCTCTTGAAGGGACTTTTGTGATAAAGAGCCA AGTTCAGAAGCATAGCGTGTACCGAAAATGAAGACTCTCCTATCTACTGCTACAGATCCTGTTGAAGAAAGAGCTTACCCCTTTCCCCCGGAAAACTTGC AATCCTGTAGTTCCCATATGTGTGGCATATGTCAGTTATGAAATTATTATAATTCAGCCTTCAAACTACTACTGATCAACTAAAGGAAAGCTAATAAGGT ATTTCTTTTAAACAAGTATTCTGGAAAAGTAATAACTATGGCACAAATGTTCAGGAGTGTATATAAAAATATGTGGGCTCTCGATTTATTTGAGCAAACA TTGCAATGAGGGTGTTCATTATGCTTCTAAGTAAGCTTTAACTAGACCACTTTCTTCTTATGTCAGATTGTGCTGGTTCTAGCTCATAATAATGAAAAAA ATAGAATTATATTTTGTATGAATTGTTTCTAACAAACCTTGATCTGTATATACTTGTGAGGGGTTGTTTGGTTGCCTAATTGTTGATTGGTTGGTTAGTT GGGCAAAATCATTTATTACATGCAAAAATAGAAAATTATTTGTTAAATTCAGAGAAAATATGTGAAGTTTACAAAGGAACCAAAATGATAATGGGAGAAT TTAGTCTTAAAAGTTTAGGTTGTCAGAGTTTATCTGATATACAAAAAAGTAGGATCAAAGTCTAGGAACAAACATTGGTTATTTCACTGAAACAGATTTT TAAAGAGCATATTAAGAAATTAAGACCATTAGATCATCTCTTTCATAATGATATGATGTTATTTCCATTGACGGCAAATCTATACTGTTCCTTGGTTTTA GAGTTGGGTATTCTTTCAAAAGTGAATTTAGGCACATGCATGTACATTGTATTTATAAAGATTATATATGTAGTTTCCAAGGAAGAAACAAAGACCTATA CAGTTTAGACTTTATTTGTTTGGTGAACGTGCTGTTGTGTTTGGCATAGCTAGAGAAATGTAAGGTAAAAGGCTCACTTTGTTTTCCAGTGGGTCCAGAG TCTTCTCTATACCCAACATATGTTTACTTTATGAACTTAAATGGAAATTAATTTATTGTAGACTACATCTCTATTTGGAATGATGAGGTAAATGTATACC TTAGCATTTTCTTTAACAAAAATGTTCTGTGTGTCAGGAAAGAGGTGTGAGAGTGGTAGGCAGCCTGCCGCAAACACACGGATGGCTCCCCCCGCCACGA AGGTTGAGAACAAAGCCAGGGGGCCCAGAGGAGCAATAGCCCTGGGCCACAAGCGTGGGTAGGCCTTTCACGTATTCCGTCTGCACAGGCAACCAAGGCC AGTAGAAAGCTATGGCTGCAAAACCCTGGGGTGGACGATGTTTGATGATTAGACGGTCATCTCTAACTACTAAACTAATATCTGCATTCTTGTTAACATA AATCTCTCCTTGGCTATTTTAATAGCCACAGTCCCAAACTTCATCCCAGCTTAGATTTCTCAGCACTGAGGTAAACTCTGCATTGTCATCCCAGCGTACA CCTTTAATGTTTTATTGATTTCACTGGCACTGTATTTGGACCTGTCCTTGTATATGTAGAGACATATGTGGCTTCATTGGTAATTTACAAGCAAAAGATG ACATGACGTGACACCTGTATGAAAATGTGATGATTGAACTCCCTGTGTACAGCGAGTGAATTAAAATGTCTGCCTCTCCAGACATTTCTTAATGATTCCA CTTAATAGACTCTATGTGTGCTGAATGTTCCTGTGTACATATGTGTGTTAAATAAAACAATTGTATTGAAGACTGTTTTTCTC

refseq_WDR7.F2 (forward primer)
refseq_WDR7.R2 (reverse primer)
Single exon skipping

Frame 0

GGTGTLQYHWGDGGCIALAAPRIIPAGSTHPAS SVVPPYPCPPWLGRPPAV**ATSRHEMKL*QV*K HKHNGRKQPCSTHCSLGSKSAHTLHLSRTFNR* WGHDRNRMSRRTNMSLGSFSRTAN*SSSTVVWS YSINHLFV*SLCFQ*QTVYCECI*KWRDVPLGCE *WQMY*IYKISLHTYWHTVLPVLCWESARRKAF MPRTLP*NPCCGCYQP*SIILLSIKDITRLD*L HEYYSIPPNTRGHSGSTLGDWHPEGLDCYLGNK* HAGY*ANI*GGIQTNLLSELPKHLFLCIYTKVT FGCVFQILEGVRCRRLFLVVFRS**KWTDMDRG GLCLIR*SHHLDRKWAKLYLQTTCQLPSS**FIP Q*CGEGS*KFNSSCTTYPLGSKR*RVANLSSCY SVLLWMQRIFP*TVNSG*FFWKVEYLEHIRHS* *TGK*RRAGNDNFY*FARGI**TESLSCWNYRSA ECDSQ***TS*SNCKCVHTSTWTTCLWS*RWKH SYCTCHTDGHSTAVARGTHAQKRLATSQNTPWS SEQSHMFAISSSGLSSV*SKIPDIWRCGFFSHNL GHIFWRNETYLLCSWW*DYSTSSST*KL*CKST ALHLLCSQ*PLSRTSKFAREKMHNVGISSPFSY SSNQMEAF**LPGGGVFRWFCVRLANGYWCIGSL CDGDNSS*DSKRL**SCSCCC*FT*SSSSQPKT SYDET*SCCS*KYGPS*ATNPCN*PLGF*GI*Q GKFT*IFS*LPDGSSNKDKPNRPGHTCAIL*CGS VDYSTPD*RSL*AEYCSYFPREFAKSIWQFRQR GLFFNWKTSSSSLPTSERNDQREHQGTPP***R GG*GDNEAEKGRK*S*ISVQQIKAIDPIRI*FNY GHCKAVYVLPSRLGFE*STG*SLPGSPWNAETP LHRIVWPLVKRRPYVTDAAGL*SACL*TVTWEN RSRKEAASV*GSRKGNLRSVPCRHHTASPVYHFF GKYFNEYDQCNFYW*SYEEGSYQAT*TKHPRPF *GKGFPSNFQ*YCARTD*TRLESVSCYALCYAA RPTGIG*I*ASPSGDAGPKMARSMLGGERSRAGP ASGGTEKN*AGRQEGSH*CLGSLLTSVHRPRHI TWSHIRSRADYHHGS*CLRA*SKSPGGRA*PC* R*HHHWLLIKCPTNEKNFYILRGKTEASYRYCFT WSNRS*IWC*N*TS*TIDQTSKL*PNS*GIRVD *WWIQLLAGQTYLQGTDVSSATASKPQTSSTQH YPKNSH*SDWTWVHCLGALHGCVRCSDGASRTLC RCRETTCQHHNGVASEPSS*LGPLCEACPLAHC HRQTTRLHHHHSQRGTQTYGSCSKYPITAEYAH NNSCTS*RGNFESH*NSY*KDAHRCCGSSRGGYG HHYVLP*RIFS*KERSSRMFPSHLQVLHGQLL* AESQNSSWSSPWFSGPVRHPDWKMSDNPWTQGT NHCSGFCS*WKISCHLLKH*QPHFFLADEHVTAG KHRHAELGTSAALH*NLPGAPCAARVPRLPQCP QAGPAHLDFQPQRHPHGP*REGAPLHGLMLLPA AVTAF*FSKLSKPMLLCPSSHQIVPRGLPTPVPS SGTAGSCHLCMLLRGRTRSCHLSIQRHAHMLCR MWPSCHQVVFPCQRWQGKASGSWERSCCLVQQK HKNQ*TL*LHSQPRSAFLAISTAPLKCCLNLAVL TLGVEVMWQSSRLKLLPFELPKILFTKKILCLH VLFFW*LLGNYSIQFPRV*LPPSLSTANQFEIH D*LCTQKYFPCRK*FSRHLAF*SAHLLLK**SI* *FKIKIITPYDLVNVIIQSL*LIS*RDFCDKEP SSEA*RVPKMKTLLSTATDPVEERAYPFPPENL QSCSSHMCGICQL*NYYNSAFKLLLIN*RKANKV FLLNKYSGKVITMAQMFRSVYKNMWALDLFEQT LQ*GCSLCF*VSFN*TTFFLCQIVLVLAHNNEK NRIIFCMNCF*QTLICIYL*GVVWLPNC*LVG*L GKIIYYMQK*KIIC*IQRKYVKFTKEPK**WEN LVLKV*VVRVYLIYKKVGSKSRNKHWLFH*NRF LKSILRN*DH*IISFIMI*CYFH*RQIYTVPWF* SWVFFQK*I*AHACTLYL*RLYM*FPRKKQRPI QFRLYLFGERAVVFGIAREM*GKRLTLFSSGSR VFSIPNICLLYELKWKLIYCRLHLYLE**GKCIP *HFL*QKCSVCQERGVRVVGSLPQTHGWLPPPR RLRTKPGGPEEQ*PWATSVGRPFTYSVCTGNQG Q*KAMAAKPWGGRCLMIRRSSLTTKLISAFLLT* ISPWLF**PQSQTSSQLRFLSTEVNSALSSQRT PLMFY*FHWHCIWTCPCICRDICGFIGNLQAKD DMT*HLYENVMIELPVYSE*IKMSASPDIS**FH LIDSMCAECSCVHMCVK*NNCIEDCFS

Frame 1

AAPAPCSITGETAAV*RLPPHGLSQQDLRTPHP P*FRPILVLLGWGAHRRSDRLHRGMR*SCDRFE NTNTMAGNSLVLPIVLWGRKAPTHCISAVLLTDD GATIVTGCHDGQICLWDLSVELQINPRALLFGH TASITCLSKACASSDKQYIVSASESGEMCLWDV SDGRCIEFTKLACTHTGIQFYQFSVGNQREGRLL CHGHYPEILVVDATSLEVLYSLVSKISPDWISS MSIIRSHRTQEDTVVALSVTGILKVWIVTSEIS DMQDTEPIFEEESKPIYCQNCQSISFCAFTQRSL LVVCSKYWRVFDAGDYSLLCSGPSENGQTWTGG DFVSSDKVIIWTENGQSYIYKLPASCLPASDSF RSDVGKAVENLIPPVQHILLDRKDKELLICPPVT RFFYGCREYFHKLLIQGDSSGRLNIWNISDTAD KQGSEEGLAMTTSISLQEAFDKLNPCPAGIIDQ LSVIPNSNEPLKVTASVYIPAHGRLVCGREDGSI VIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGH RNKVTCLLYPHQVSARYDQRYLISGGVDFSVII WDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQ HCICSVASDHSVGLLSLREKKCIMLASRHLFPI QVIKWRPSDDYLVVGCSDGSVYVWQMDTGALDR CVMGITAVEILNACDEAVPAAVDSLSHPAVNLKQ AMTRRSLAALKNMAHHKLQTLATNLLASEASDK GNLPKYSHNSLMVQAIKTNLTDPDIHVLFFDVE ALIIQLLTEEASRPNTALISPENLQKASGSSDKG GSFLTGKRAAVLFQQVKETIKENIKEHLLDDEE EDEEIMRQRREESDPEYRSSKSKPLTLLEYNLT MDTAKLFMSCLHAWGLNEVLDEVCLDRLGMLKPH CTVSFGLLSRGGHMSLMLPGYNQPACKLSHGKT EVGRKLPASEGVGKGTYGVSRAVTTQHLLSIIS LANTLMSMTNATFIGDHMKKGPTRPPRPSTPDLS KARGSPPTSSNIVQGQIKQGWSQLAAMHCVMLP DLLGLDKFRPPLLEMLARRWQDRCLEVREAAQA LLLAELRRIEQAGRKEAIDAWAPYLPQYIDHVIS PGVTSEAAQTITTAPDASGPEAKVQEEEHDLVD DDITTGCLSSVPQMKKISTSYEERRKQATAIVL LGVIGAEFGAEIEPPKLLTRPRSSSQIPEGFGLT SGGSNYSLARHTCKALTFLLLQPPSPKLPPHST IRRTAIDLIGRGFTVWEPYMDVSAVLMGLLELC ADAEKQLANITMGLPLSPAADSARSARHALSLIA TARPPAFITTIAKEVHRHTALAANTQSQQNMHT TTLARAKGEILRVIEILIEKMPTDVVDLLVEVM DIIMYCLEGSLVKKKGLQECFPAICRFYMVSYYE RNHRIAVGARHGSVALYDIRTGKCQTIHGHKGP ITAVAFAPDGRYLATYSNTDSHISFWQMNTSLL GSIGMLNSAPQLRCIKTYQVPPVQPASPGSHNAL KLARLIWTSNRNVILMAHDGKEHRFMV*CCCLP P*LRFSSLNYPSRCCSVLPHTRLFPGACPPQCH PVARPGLVTCACFSGAEPARAICRFRGTHTCSAG CGHPVTR*FFPARDGRGKPVVPGNALVAWCNRS TKINKHCDCTPSPDQHF*PSQPHL*SAA*IWPF *HWVLRSCGSPHD*NYCPLNYLKYCLPKRFCVYM FFSSGDC*EITQSNFLGFSYHLLYQQLTNLRFM INYVHKNIFLVENSFPDT*PSEVLISCLNDSLF SSLK*K*SLPMI*LM*LSSHCN*SLEGTFVIKSQ VQKHSVYRK*RLSYLLLQILLKKELTPFPRKTC NPVVPICVAYVSYEIIIIQPSNYY*STKGKLIR YFF*TSILEK**LWHKCSGVYIKICGLSIYLSKH CNEGVHYASK*ALTRPLSSYVRLCWF*LIIMKK IELYFV*IVSNKP*SVYTCEGLFGCLIVDWLVS WAKSFITCKNRKLFVKFRENM*SLQRNQNDNGRI *S*KFRLSEFI*YTKK*DQSLGTNIGYFTETDF *RAY*EIKTIRSSLS**YDVISIDGKSILFLGF RVGYSFKSEFRHMHVHCIYKDYICSFQGRNKDLY SLDFICLVNVLLCLA*LEKCKVKGSLCFPVGPE SSLYPTYVYFMNLNGN*FIVDYISIWNDEVNVY LSIFFNKNVLCVRKEV*EW*AACRKHTDGSPRHE G*EQSQGAQRSNSPGPQAWVGLSRIPSAQATKA SRKLWLQNPGVDDV**LDGHL*LLN*YLHSC*H KSLLGYFNSHSPKLHPSLDFSALR*TLHCHPSVH L*CFIDFTGTVFGPVLVYVETYVASLVIYKQKM T*RDTCMKM**LNSLCTASELKCLPLQTFLNDS T**TLCVLNVPVYICVLNKTIVLKTVFL

Frame 2

RHRHLAVSLGRRRLYSACRPTDYPSRIYAPRIL RSSALSLSSLAGAPTGGLIGYIAA*DEAVTGLK TQTQWQETALFYPLFFGVEKRPHIASQPYF*QM MGPRS*QDVTTDKYVSGIFQ*NCKLILEHCCLVI QHQSLVCLKLVLPVTNSIL*VHLKVERCASGM* VMADVLNLQN*LAHILAYSSTSSLLGISEKEGF YATDITLKSLLWMLPALKYYTP*YQRYHQTGLAP *VLFDPTEHKRTQW*HSR*LAS*RSGLLPRK*V TCRILSQYLRRNPNQFIVRIAKASLFVHLHKGH FWLCVPNIGGCSMPETIPCCVQVLVKMDRHGPGG TLSHQIKSSFGQKMGKVIFTNYLPVAFQLVIHS AVMWGRQLKI*FLLYNISSWIEKIKSC*FVLLL LGSSMDAENISINC*FRVILLEG*IFGTYQTQLI NREVKKGWQ*QLLLVCKRHLIN*ILVLLEL*IS *V*FPIVMNLLK*LQVCTYQHMDDLFVVVKMEA *LLYLPHRRP*YSCCKGNTCSEEVGHLTEHSVVI GTKSHVCYILIRSQLGMIKDT*YLEVWIFQS*F GTYFLEK*NISSVFMVVRLLNF*FHLKTVVQEY STASAL*PVTTQ*DF*VCERKNA*CWHLVTFFLF K*SNGGLLMITWWWGVQMVLCTSGKWILVHWIV V*WG*QQLRF*TLVMKLFLLLLIHLVIQQST*N KL*RDVVLLLLKIWPIISYKPLQLTSWLLRHLTR EIYLNILITP*WFKQ*RQT*QTRTYMCYSLMWK R*LFNS*LKKPLGRILLLFPQRICKKHLAVQTK GALF*LENEQQFSSNK*KKRSKRTSRNTSLMMKR RMRR**GREGKKVILNIGPANQSH*PY*NII*L WTLQSCLCPAFTPGV*MKYWMKFAWIALEC*NP TAPYRLASCQEEAICH*CCRVIISLLVNCHMGKQ K*EGSCQRLRE*ERELTECPVPSPHSISCLSFL WQIL**V*PMQLLLVII*RRVLPGHLDQAPQTF LRQGVPLQLPVILCKDRLNKVGVS*LLCTVLCCQ TYWDWINLGLPFWRCWPEDGKIDAWR*EKPRRP CFWRN*EELSRQAGRKPLMPGLLTYLST*TTSY HLESHQKPRRLSPRLLMPQGLKQKSRRKSMTLLT MTSPLVAYQVSHK*KKFLHLTRKDGSKLPLLFY LE**ELNLVLKLNLLNY*PDLEALAKFLRDSG* LVVDPTTRWPDILARH*RFFCYSLQAPNFLHTAL SEEQPLI*LDVGSLFGSLTWMCPLF*WGFSNFV PMPRNNLPTSQWGCL*AQQLTRPALRGMPSRSL PPPDHPPSSPP*PKRYTDIRLLQQIPNHSRICTQ QLLHELKGKF*ESLKFLLKRCPQMLWIFSWRLW TSLCTALKDL*LKRKVFKNVSQPSAGSTWSAIM SGITE*QLELAMVQWPCTTSGLENVRQSMDTRDQ SLQWLLLLMEDILPPTQTLTATFLFGR*TRHCW EASAC*TRHLSCAALKPTRCPLCSPRPPAPTMP SSWPGSSGLPTATSSSWPMTGRSTASWSNAAACR RDCVLVL*IIQADVALSFLTPDCSQGPAHPSAI QWHGRVLSLVHASQGQNPLVPSVDSEARTHALQ DVAILSPGSFSLPEMAGESQWFLGTLLLLGATEA QKSINTVIALPAQISIFSHLNRTSEVLLESGRS DTGC*GHVAVLTIEIIAL*IT*NIVYQKDSVFT CSFLLVIARKLLNPIS*GLATTFFINS*PI*DS* LIMYTKIFSL*KIVFQTLSLLKCSSLA*MIVYL VV*NKNNHSL*SS*CNYPVTVTNLLKGLL**RA KFRSIACTENEDSPIYCYRSC*RKSLPLSPGKLA IL*FPYVWHMSVMKLL*FSLQTTTDQLKES**G ISFKQVFWKSNNYGTNVQECI*KYVGSRFI*AN IAMRVFIMLLSKL*LDHFLLMSDCAGSSS***KK *NYILYELFLTNLDLYILVRGCLVA*LLIGWLV GQNHLLHAKIENYLLNSEKICEVYKGTKMIMGE FSLKSLGCQSLSDIQKSRIKV*EQTLVISLKQIF KEHIKKLRPLDHLFHNDMMLFPLTANLYCSLVL ELGILSKVNLGTCMYIVFIKIIYVVSKEETKTY TV*TLFVW*TCCCVWHS*RNVR*KAHFVFQWVQS LLYTQHMFTL*T*MEINLL*TTSLFGMMR*MYT LAFSLTKMFCVSGKRCESGRQPAANTRMAPPAT KVENKARGPRGAIALGHKRG*AFHVFRLHRQPRP VESYGCKTLGWTMFDD*TVISNY*TNICILVNI NLSLAILIATVPNFIPA*ISQH*GKLCIVIPAY TFNVLLISLALYLDLSLYM*RHMWLHW*FTSKR* HDVTPV*KCDD*TPCVQRVN*NVCLSRHFLMIP LNRLYVC*MFLCTYVC*IKQLY*RLFF

Sequence NM_015285

GGCGGCACCGGCACCTTGCAGTATCACTGGGGAGACGGCGGCTGTATAGCGCTTGCCGCCCCACGGATTATCCCAGCAGGATCTACGCACCCCGCATCCT CCGTAGTTCCGCCCTATCCTTGTCCTCCTTGGCTGGGGCGCCCACCGGCGGTCTGATAGGCTACATCGCGGCATGAGATGAAGCTGTGACAGGTTTGAAA ACACAAACACAATGGCAGGAAACAGCCTTGTTCTACCCATTGTTCTTTGGGGTCGAAAAGCGCCCACACATTGCATCTCAGCCGTACTTTTAACAGATGA TGGGGCCACGATCGTAACAGGATGTCACGACGGACAAATATGTCTCTGGGATCTTTCAGTAGAACTGCAAATTAATCCTCGAGCACTGTTGTTTGGTCAT ACAGCATCAATCACTTGTTTGTCTAAAGCTTGTGCTTCCAGTGACAAACAGTATATTGTGAGTGCATCTGAAAGTGGAGAGATGTGCCTCTGGGATGTGA GTGATGGCAGATGTATTGAATTTACAAAATTAGCTTGCACACATACTGGCATACAGTTCTACCAGTTCTCTGTTGGGAATCAGCGAGAAGGAAGGCTTTT ATGCCACGGACATTACCCTGAAATCCTTGTTGTGGATGCTACCAGCCTTGAAGTATTATACTCCTTAGTATCAAAGATATCACCAGACTGGATTAGCTCC ATGAGTATTATTCGATCCCACCGAACACAAGAGGACACAGTGGTAGCACTCTCGGTGACTGGCATCCTGAAGGTCTGGATTGTTACCTCGGAAATAAGTG ACATGCAGGATACTGAGCCAATATTTGAGGAGGAATCCAAACCAATTTATTGTCAGAATTGCCAAAGCATCTCTTTTTGTGCATTTACACAAAGGTCACT TTTGGTTGTGTGTTCCAAATATTGGAGGGTGTTCGATGCCGGAGACTATTCCTTGTTGTGTTCAGGTCCTAGTGAAAATGGACAGACATGGACCGGGGGG GACTTTGTCTCATCAGATAAAGTCATCATTTGGACAGAAAATGGGCAAAGTTATATTTACAAACTACCTGCCAGTTGCCTTCCAGCTAGTGATTCATTCC GCAGTGATGTGGGGAAGGCAGTTGAAAATTTAATTCCTCCTGTACAACATATCCTCTTGGATCGAAAAGATAAAGAGTTGCTAATTTGTCCTCCTGTTAC TCGGTTCTTCTATGGATGCAGAGAATATTTCCATAAACTGTTAATTCAGGGTGATTCTTCTGGAAGGTTGAATATTTGGAACATATCAGACACAGCTGAT AAACAGGGAAGTGAAGAAGGGCTGGCAATGACAACTTCTATTAGTTTGCAAGAGGCATTTGATAAACTGAATCCTTGTCCTGCTGGAATTATAGATCAGC TGAGTGTGATTCCCAATAGTAATGAACCTCTTAAAGTAACTGCAAGTGTGTACATACCAGCACATGGACGACTTGTTTGTGGTCGTGAAGATGGAAGCAT AGTTATTGTACCTGCCACACAGACGGCCATAGTACAGCTGTTGCAAGGGGAACACATGCTCAGAAGAGGTTGGCCACCTCACAGAACACTCCGTGGTCAT CGGAACAAAGTCACATGTTTGCTATATCCTCATCAGGTCTCAGCTCGGTATGATCAAAGATACCTGATATCTGGAGGTGTGGATTTTTCAGTCATAATTT GGGACATATTTTCTGGAGAAATGAAACATATCTTCTGTGTTCATGGTGGTGAGATTACTCAACTTCTAGTTCCACCTGAAAACTGTAGTGCAAGAGTACA GCACTGCATCTGCTCTGTAGCCAGTGACCACTCAGTAGGACTTCTAAGTTTGCGAGAGAAAAAATGCATAATGTTGGCATCTCGTCACCTTTTTCCTATT CAAGTAATCAAATGGAGGCCTTCTGATGATTACCTGGTGGTGGGGTGTTCAGATGGTTCTGTGTACGTCTGGCAAATGGATACTGGTGCATTGGATCGTT GTGTGATGGGGATAACAGCAGTTGAGATTCTAAACGCTTGTGATGAAGCTGTTCCTGCTGCTGTTGATTCACTTAGTCATCCAGCAGTCAACCTAAAACA AGCTATGACGAGACGTAGTCTTGCTGCTCTTAAAAATATGGCCCATCATAAGCTACAAACCCTTGCAACTAACCTCTTGGCTTCTGAGGCATCTGACAAG GGAAATTTACCTAAATATTCTCATAACTCCCTGATGGTTCAAGCAATAAAGACAAACCTAACAGACCCGGACATACATGTGCTATTCTTTGATGTGGAAG CGTTGATTATTCAACTCCTGACTGAAGAAGCCTCTAGGCCGAATACTGCTCTTATTTCCCCAGAGAATTTGCAAAAAGCATCTGGCAGTTCAGACAAAGG GGGCTCTTTTTTAACTGGAAAACGAGCAGCAGTTCTCTTCCAACAAGTGAAAGAAACGATCAAAGAGAACATCAAGGAACACCTCCTTGATGATGAAGAG GAGGATGAGGAGATAATGAGGCAGAGAAGGGAAGAAAGTGATCCTGAATATCGGTCCAGCAAATCAAAGCCATTGACCCTATTAGAATATAATTTAACTA TGGACACTGCAAAGCTGTTTATGTCCTGCCTTCACGCCTGGGGTTTGAATGAAGTACTGGATGAAGTTTGCCTGGATCGCCTTGGAATGCTGAAACCCCA CTGCACCGTATCGTTTGGCCTCTTGTCAAGAGGAGGCCATATGTCACTGATGCTGCCGGGTTATAATCAGCCTGCTTGTAAACTGTCACATGGGAAAACA GAAGTAGGAAGGAAGCTGCCAGCGTCTGAGGGAGTAGGAAAGGGAACTTACGGAGTGTCCCGTGCCGTCACCACACAGCATCTCCTGTCTATCATTTCTT TGGCAAATACTTTAATGAGTATGACCAATGCAACTTTTATTGGTGATCATATGAAGAAGGGTCCTACCAGGCCACCTAGACCAAGCACCCCAGACCTTTC TAAGGCAAGGGGTTCCCCTCCAACTTCCAGTAATATTGTGCAAGGACAGATTAAACAAGTTGCTGCACCTGTCGTTTCCGCTCGGTCTGATGCTGATCAC TCTGGCTCTGACCCTCCTTCTGCTCCTGCTTTACATACCTGTTTCTTAGTAAATGAAGGTTGGAGTCAGTTAGCTGCTATGCACTGTGTTATGCTGCCAG ACCTACTGGGATTGGATAAATTTAGGCCTCCCCTTCTGGAGATGCTGGCCCGAAGATGGCAAGATCGATGCTTGGAGGTGAGAGAAGCCGCGCAGGCCCT GCTTCTGGCGGAACTGAGAAGAATTGAGCAGGCAGGCAGGAAGGAAGCCATTGATGCCTGGGCTCCTTACTTACCTCAGTACATAGACCACGTCATATCA CCTGGAGTCACATCAGAAGCCGCGCAGACTATCACCACGGCTCCTGATGCCTCAGGGCCTGAAGCAAAAGTCCAGGAGGAAGAGCATGACCTTGTTGACG ATGACATCACCACTGGTTGCTTATCAAGTGTCCCACAAATGAAAAAAATTTCTACATCTTACGAGGAAAGACGGAAGCAAGCTACCGCTATTGTTTTACT TGGAGTAATAGGAGCTGAATTTGGTGCTGAAATTGAACCTCCTAAACTATTGACCAGACCTCGAAGCTCTAGCCAAATTCCTGAGGGATTCGGGTTGACT AGTGGTGGATCCAACTACTCGCTGGCCAGACATACTTGCAAGGCACTGACGTTTCTTCTGCTACAGCCTCCAAGCCCCAAACTTCCTCCACACAGCACTA TCCGAAGAACAGCCATTGATCTGATTGGACGTGGGTTCACTGTTTGGGAGCCTTACATGGATGTGTCCGCTGTTCTGATGGGGCTTCTCGAACTTTGTGC CGATGCCGAGAAACAACTTGCCAACATCACAATGGGGTTGCCTCTGAGCCCAGCAGCTGACTCGGCCCGCTCTGCGAGGCATGCCCTCTCGCTCATTGCC ACCGCCAGACCACCCGCCTTCATCACCACCATAGCCAAAGAGGTACACAGACATACGGCTCTTGCAGCAAATACCCAATCACAGCAGAATATGCACACAA CAACTCTTGCACGAGCTAAAGGGGAAATTTTGAGAGTCATTGAAATTCTTATTGAAAAGATGCCCACAGATGTTGTGGATCTTCTCGTGGAGGTTATGGA CATCATTATGTACTGCCTTGAAGGATCTTTAGTTAAAAAGAAAGGTCTTCAAGAATGTTTCCCAGCCATCTGCAGGTTCTACATGGTCAGCTATTATGAG CGGAATCACAGAATAGCAGTTGGAGCTCGCCATGGTTCAGTGGCCCTGTACGACATCCGGACTGGAAAATGTCAGACAATCCATGGACACAAGGGACCAA TCACTGCAGTGGCTTTTGCTCCTGATGGAAGATATCTTGCCACCTACTCAAACACTGACAGCCACATTTCTTTTTGGCAGATGAACACGTCACTGCTGGG AAGCATCGGCATGCTGAACTCGGCACCTCAGCTGCGCTGCATTAAAACCTACCAGGTGCCCCCTGTGCAGCCCGCGTCCCCCGGCTCCCACAATGCCCTC AAGCTGGCCCGGCTCATCTGGACTTCCAACCGCAACGTCATCCTCATGGCCCATGACGGGAAGGAGCACCGCTTCATGGTCTAATGCTGCTGCCTGCCGC CGTGACTGCGTTTTAGTTCTCTAAATTATCCAAGCCGATGTTGCTCTGTCCTTCCTCACACCAGATTGTTCCCAGGGGCCTGCCCACCCCAGTGCCATCC AGTGGCACGGCCGGGTCTTGTCACTTGTGCATGCTTCTCAGGGGCAGAACCCGCTCGTGCCATCTGTCGATTCAGAGGCACGCACACATGCTCTGCAGGA TGTGGCCATCCTGTCACCAGGTAGTTTTTCCCTGCCAGAGATGGCAGGGGAAAGCCAGTGGTTCCTGGGAACGCTCTTGTTGCTTGGTGCAACAGAAGCA CAAAAATCAATAAACACTGTGATTGCACTCCCAGCCCAGATCAGCATTTTTAGCCATCTCAACCGCACCTCTGAAGTGCTGCTTGAATCTGGCCGTTCTG ACACTGGGTGTTGAGGTCATGTGGCAGTCCTCACGATTGAAATTATTGCCCTTTGAATTACCTAAAATATTGTTTACCAAAAAGATTCTGTGTTTACATG TTCTTTTCTTCTGGTGATTGCTAGGAAATTACTCAATCCAATTTCCTAGGGTTTAGCTACCACCTTCTTTATCAACAGCTAACCAATTTGAGATTCATGA TTAATTATGTACACAAAAATATTTTCCTTGTAGAAAATAGTTTTCCAGACACTTAGCCTTCTGAAGTGCTCATCTCTTGCTTAAATGATAGTCTATTTAG TAGTTTAAAATAAAAATAATCACTCCCTATGATCTAGTTAATGTAATTATCCAGTCACTGTAACTAATCTCTTGAAGGGACTTTTGTGATAAAGAGCCAA GTTCAGAAGCATAGCGTGTACCGAAAATGAAGACTCTCCTATCTACTGCTACAGATCCTGTTGAAGAAAGAGCTTACCCCTTTCCCCCGGAAAACTTGCA ATCCTGTAGTTCCCATATGTGTGGCATATGTCAGTTATGAAATTATTATAATTCAGCCTTCAAACTACTACTGATCAACTAAAGGAAAGCTAATAAGGTA TTTCTTTTAAACAAGTATTCTGGAAAAGTAATAACTATGGCACAAATGTTCAGGAGTGTATATAAAAATATGTGGGCTCTCGATTTATTTGAGCAAACAT TGCAATGAGGGTGTTCATTATGCTTCTAAGTAAGCTTTAACTAGACCACTTTCTTCTTATGTCAGATTGTGCTGGTTCTAGCTCATAATAATGAAAAAAA TAGAATTATATTTTGTATGAATTGTTTCTAACAAACCTTGATCTGTATATACTTGTGAGGGGTTGTTTGGTTGCCTAATTGTTGATTGGTTGGTTAGTTG GGCAAAATCATTTATTACATGCAAAAATAGAAAATTATTTGTTAAATTCAGAGAAAATATGTGAAGTTTACAAAGGAACCAAAATGATAATGGGAGAATT TAGTCTTAAAAGTTTAGGTTGTCAGAGTTTATCTGATATACAAAAAAGTAGGATCAAAGTCTAGGAACAAACATTGGTTATTTCACTGAAACAGATTTTT AAAGAGCATATTAAGAAATTAAGACCATTAGATCATCTCTTTCATAATGATATGATGTTATTTCCATTGACGGCAAATCTATACTGTTCCTTGGTTTTAG AGTTGGGTATTCTTTCAAAAGTGAATTTAGGCACATGCATGTACATTGTATTTATAAAGATTATATATGTAGTTTCCAAGGAAGAAACAAAGACCTATAC AGTTTAGACTTTATTTGTTTGGTGAACGTGCTGTTGTGTTTGGCATAGCTAGAGAAATGTAAGGTAAAAGGCTCACTTTGTTTTCCAGTGGGTCCAGAGT CTTCTCTATACCCAACATATGTTTACTTTATGAACTTAAATGGAAATTAATTTATTGTAGACTACATCTCTATTTGGAATGATGAGGTAAATGTATACCT TAGCATTTTCTTTAACAAAAATGTTCTGTGTGTCAGGAAAGAGGTGTGAGAGTGGTAGGCAGCCTGCCGCAAACACACGGATGGCTCCCCCCGCCACGAA GGTTGAGAACAAAGCCAGGGGGCCCAGAGGAGCAATAGCCCTGGGCCACAAGCGTGGGTAGGCCTTTCACGTATTCCGTCTGCACAGGCAACCAAGGCCA GTAGAAAGCTATGGCTGCAAAACCCTGGGGTGGACGATGTTTGATGATTAGACGGTCATCTCTAACTACTAAACTAATATCTGCATTCTTGTTAACATAA ATCTCTCCTTGGCTATTTTAATAGCCACAGTCCCAAACTTCATCCCAGCTTAGATTTCTCAGCACTGAGGTAAACTCTGCATTGTCATCCCAGCGTACAC CTTTAATGTTTTATTGATTTCACTGGCACTGTATTTGGACCTGTCCTTGTATATGTAGAGACATATGTGGCTTCATTGGTAATTTACAAGCAAAAGATGA CATGACGTGACACCTGTATGAAAATGTGATGATTGAACTCCCTGTGTACAGCGAGTGAATTAAAATGTCTGCCTCTCCAGACATTTCTTAATGATTCCAC TTAATAGACTCTATGTGTGCTGAATGTTCCTGTGTACATATGTGTGTTAAATAAAACAATTGTATTGAAGACTGTTTTTCTC

refseq_WDR7.F2 (forward primer)
refseq_WDR7.R2 (reverse primer)
Single exon skipping

Frame 0

GGTGTLQYHWGDGGCIALAAPRIIPAGSTHPAS SVVPPYPCPPWLGRPPAV**ATSRHEMKL*QV*K HKHNGRKQPCSTHCSLGSKSAHTLHLSRTFNR* WGHDRNRMSRRTNMSLGSFSRTAN*SSSTVVWS YSINHLFV*SLCFQ*QTVYCECI*KWRDVPLGCE *WQMY*IYKISLHTYWHTVLPVLCWESARRKAF MPRTLP*NPCCGCYQP*SIILLSIKDITRLD*L HEYYSIPPNTRGHSGSTLGDWHPEGLDCYLGNK* HAGY*ANI*GGIQTNLLSELPKHLFLCIYTKVT FGCVFQILEGVRCRRLFLVVFRS**KWTDMDRG GLCLIR*SHHLDRKWAKLYLQTTCQLPSS**FIP Q*CGEGS*KFNSSCTTYPLGSKR*RVANLSSCY SVLLWMQRIFP*TVNSG*FFWKVEYLEHIRHS* *TGK*RRAGNDNFY*FARGI**TESLSCWNYRSA ECDSQ***TS*SNCKCVHTSTWTTCLWS*RWKH SYCTCHTDGHSTAVARGTHAQKRLATSQNTPWS SEQSHMFAISSSGLSSV*SKIPDIWRCGFFSHNL GHIFWRNETYLLCSWW*DYSTSSST*KL*CKST ALHLLCSQ*PLSRTSKFAREKMHNVGISSPFSY SSNQMEAF**LPGGGVFRWFCVRLANGYWCIGSL CDGDNSS*DSKRL**SCSCCC*FT*SSSSQPKT SYDET*SCCS*KYGPS*ATNPCN*PLGF*GI*Q GKFT*IFS*LPDGSSNKDKPNRPGHTCAIL*CGS VDYSTPD*RSL*AEYCSYFPREFAKSIWQFRQR GLFFNWKTSSSSLPTSERNDQREHQGTPP***R GG*GDNEAEKGRK*S*ISVQQIKAIDPIRI*FNY GHCKAVYVLPSRLGFE*STG*SLPGSPWNAETP LHRIVWPLVKRRPYVTDAAGL*SACL*TVTWEN RSRKEAASV*GSRKGNLRSVPCRHHTASPVYHFF GKYFNEYDQCNFYW*SYEEGSYQAT*TKHPRPF *GKGFPSNFQ*YCARTD*TSCCTCRFRSV*C*S LWL*PSFCSCFTYLFLSK*RLESVSCYALCYAAR PTGIG*I*ASPSGDAGPKMARSMLGGERSRAGP ASGGTEKN*AGRQEGSH*CLGSLLTSVHRPRHI TWSHIRSRADYHHGS*CLRA*SKSPGGRA*PC*R *HHHWLLIKCPTNEKNFYILRGKTEASYRYCFT WSNRS*IWC*N*TS*TIDQTSKL*PNS*GIRVD *WWIQLLAGQTYLQGTDVSSATASKPQTSSTQHY PKNSH*SDWTWVHCLGALHGCVRCSDGASRTLC RCRETTCQHHNGVASEPSS*LGPLCEACPLAHC HRQTTRLHHHHSQRGTQTYGSCSKYPITAEYAHN NSCTS*RGNFESH*NSY*KDAHRCCGSSRGGYG HHYVLP*RIFS*KERSSRMFPSHLQVLHGQLL* AESQNSSWSSPWFSGPVRHPDWKMSDNPWTQGTN HCSGFCS*WKISCHLLKH*QPHFFLADEHVTAG KHRHAELGTSAALH*NLPGAPCAARVPRLPQCP QAGPAHLDFQPQRHPHGP*REGAPLHGLMLLPAA VTAF*FSKLSKPMLLCPSSHQIVPRGLPTPVPS SGTAGSCHLCMLLRGRTRSCHLSIQRHAHMLCR MWPSCHQVVFPCQRWQGKASGSWERSCCLVQQKH KNQ*TL*LHSQPRSAFLAISTAPLKCCLNLAVL TLGVEVMWQSSRLKLLPFELPKILFTKKILCLH VLFFW*LLGNYSIQFPRV*LPPSLSTANQFEIHD *LCTQKYFPCRK*FSRHLAF*SAHLLLK**SI* *FKIKIITPYDLVNVIIQSL*LIS*RDFCDKEP SSEA*RVPKMKTLLSTATDPVEERAYPFPPENLQ SCSSHMCGICQL*NYYNSAFKLLLIN*RKANKV FLLNKYSGKVITMAQMFRSVYKNMWALDLFEQT LQ*GCSLCF*VSFN*TTFFLCQIVLVLAHNNEKN RIIFCMNCF*QTLICIYL*GVVWLPNC*LVG*L GKIIYYMQK*KIIC*IQRKYVKFTKEPK**WEN LVLKV*VVRVYLIYKKVGSKSRNKHWLFH*NRFL KSILRN*DH*IISFIMI*CYFH*RQIYTVPWF* SWVFFQK*I*AHACTLYL*RLYM*FPRKKQRPI QFRLYLFGERAVVFGIAREM*GKRLTLFSSGSRV FSIPNICLLYELKWKLIYCRLHLYLE**GKCIP *HFL*QKCSVCQERGVRVVGSLPQTHGWLPPPR RLRTKPGGPEEQ*PWATSVGRPFTYSVCTGNQGQ *KAMAAKPWGGRCLMIRRSSLTTKLISAFLLT* ISPWLF**PQSQTSSQLRFLSTEVNSALSSQRT PLMFY*FHWHCIWTCPCICRDICGFIGNLQAKDD MT*HLYENVMIELPVYSE*IKMSASPDIS**FH LIDSMCAECSCVHMCVK*NNCIEDCFS

Frame 1

AAPAPCSITGETAAV*RLPPHGLSQQDLRTPHP P*FRPILVLLGWGAHRRSDRLHRGMR*SCDRFE NTNTMAGNSLVLPIVLWGRKAPTHCISAVLLTDD GATIVTGCHDGQICLWDLSVELQINPRALLFGH TASITCLSKACASSDKQYIVSASESGEMCLWDV SDGRCIEFTKLACTHTGIQFYQFSVGNQREGRLL CHGHYPEILVVDATSLEVLYSLVSKISPDWISS MSIIRSHRTQEDTVVALSVTGILKVWIVTSEIS DMQDTEPIFEEESKPIYCQNCQSISFCAFTQRSL LVVCSKYWRVFDAGDYSLLCSGPSENGQTWTGG DFVSSDKVIIWTENGQSYIYKLPASCLPASDSF RSDVGKAVENLIPPVQHILLDRKDKELLICPPVT RFFYGCREYFHKLLIQGDSSGRLNIWNISDTAD KQGSEEGLAMTTSISLQEAFDKLNPCPAGIIDQ LSVIPNSNEPLKVTASVYIPAHGRLVCGREDGSI VIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGH RNKVTCLLYPHQVSARYDQRYLISGGVDFSVII WDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQ HCICSVASDHSVGLLSLREKKCIMLASRHLFPI QVIKWRPSDDYLVVGCSDGSVYVWQMDTGALDR CVMGITAVEILNACDEAVPAAVDSLSHPAVNLKQ AMTRRSLAALKNMAHHKLQTLATNLLASEASDK GNLPKYSHNSLMVQAIKTNLTDPDIHVLFFDVE ALIIQLLTEEASRPNTALISPENLQKASGSSDKG GSFLTGKRAAVLFQQVKETIKENIKEHLLDDEE EDEEIMRQRREESDPEYRSSKSKPLTLLEYNLT MDTAKLFMSCLHAWGLNEVLDEVCLDRLGMLKPH CTVSFGLLSRGGHMSLMLPGYNQPACKLSHGKT EVGRKLPASEGVGKGTYGVSRAVTTQHLLSIIS LANTLMSMTNATFIGDHMKKGPTRPPRPSTPDLS KARGSPPTSSNIVQGQIKQVAAPVVSARSDADH SGSDPPSAPALHTCFLVNEGWSQLAAMHCVMLP DLLGLDKFRPPLLEMLARRWQDRCLEVREAAQAL LLAELRRIEQAGRKEAIDAWAPYLPQYIDHVIS PGVTSEAAQTITTAPDASGPEAKVQEEEHDLVD DDITTGCLSSVPQMKKISTSYEERRKQATAIVLL GVIGAEFGAEIEPPKLLTRPRSSSQIPEGFGLT SGGSNYSLARHTCKALTFLLLQPPSPKLPPHST IRRTAIDLIGRGFTVWEPYMDVSAVLMGLLELCA DAEKQLANITMGLPLSPAADSARSARHALSLIA TARPPAFITTIAKEVHRHTALAANTQSQQNMHT TTLARAKGEILRVIEILIEKMPTDVVDLLVEVMD IIMYCLEGSLVKKKGLQECFPAICRFYMVSYYE RNHRIAVGARHGSVALYDIRTGKCQTIHGHKGP ITAVAFAPDGRYLATYSNTDSHISFWQMNTSLLG SIGMLNSAPQLRCIKTYQVPPVQPASPGSHNAL KLARLIWTSNRNVILMAHDGKEHRFMV*CCCLP P*LRFSSLNYPSRCCSVLPHTRLFPGACPPQCHP VARPGLVTCACFSGAEPARAICRFRGTHTCSAG CGHPVTR*FFPARDGRGKPVVPGNALVAWCNRS TKINKHCDCTPSPDQHF*PSQPHL*SAA*IWPF* HWVLRSCGSPHD*NYCPLNYLKYCLPKRFCVYM FFSSGDC*EITQSNFLGFSYHLLYQQLTNLRFM INYVHKNIFLVENSFPDT*PSEVLISCLNDSLFS SLK*K*SLPMI*LM*LSSHCN*SLEGTFVIKSQ VQKHSVYRK*RLSYLLLQILLKKELTPFPRKTC NPVVPICVAYVSYEIIIIQPSNYY*STKGKLIRY FF*TSILEK**LWHKCSGVYIKICGLSIYLSKH CNEGVHYASK*ALTRPLSSYVRLCWF*LIIMKK IELYFV*IVSNKP*SVYTCEGLFGCLIVDWLVSW AKSFITCKNRKLFVKFRENM*SLQRNQNDNGRI *S*KFRLSEFI*YTKK*DQSLGTNIGYFTETDF *RAY*EIKTIRSSLS**YDVISIDGKSILFLGFR VGYSFKSEFRHMHVHCIYKDYICSFQGRNKDLY SLDFICLVNVLLCLA*LEKCKVKGSLCFPVGPE SSLYPTYVYFMNLNGN*FIVDYISIWNDEVNVYL SIFFNKNVLCVRKEV*EW*AACRKHTDGSPRHE G*EQSQGAQRSNSPGPQAWVGLSRIPSAQATKA SRKLWLQNPGVDDV**LDGHL*LLN*YLHSC*HK SLLGYFNSHSPKLHPSLDFSALR*TLHCHPSVH L*CFIDFTGTVFGPVLVYVETYVASLVIYKQKM T*RDTCMKM**LNSLCTASELKCLPLQTFLNDST **TLCVLNVPVYICVLNKTIVLKTVFL

Frame 2

RHRHLAVSLGRRRLYSACRPTDYPSRIYAPRIL RSSALSLSSLAGAPTGGLIGYIAA*DEAVTGLK TQTQWQETALFYPLFFGVEKRPHIASQPYF*QM MGPRS*QDVTTDKYVSGIFQ*NCKLILEHCCLVI QHQSLVCLKLVLPVTNSIL*VHLKVERCASGM* VMADVLNLQN*LAHILAYSSTSSLLGISEKEGF YATDITLKSLLWMLPALKYYTP*YQRYHQTGLAP *VLFDPTEHKRTQW*HSR*LAS*RSGLLPRK*V TCRILSQYLRRNPNQFIVRIAKASLFVHLHKGH FWLCVPNIGGCSMPETIPCCVQVLVKMDRHGPGG TLSHQIKSSFGQKMGKVIFTNYLPVAFQLVIHS AVMWGRQLKI*FLLYNISSWIEKIKSC*FVLLL LGSSMDAENISINC*FRVILLEG*IFGTYQTQLI NREVKKGWQ*QLLLVCKRHLIN*ILVLLEL*IS *V*FPIVMNLLK*LQVCTYQHMDDLFVVVKMEA *LLYLPHRRP*YSCCKGNTCSEEVGHLTEHSVVI GTKSHVCYILIRSQLGMIKDT*YLEVWIFQS*F GTYFLEK*NISSVFMVVRLLNF*FHLKTVVQEY STASAL*PVTTQ*DF*VCERKNA*CWHLVTFFLF K*SNGGLLMITWWWGVQMVLCTSGKWILVHWIV V*WG*QQLRF*TLVMKLFLLLLIHLVIQQST*N KL*RDVVLLLLKIWPIISYKPLQLTSWLLRHLTR EIYLNILITP*WFKQ*RQT*QTRTYMCYSLMWK R*LFNS*LKKPLGRILLLFPQRICKKHLAVQTK GALF*LENEQQFSSNK*KKRSKRTSRNTSLMMKR RMRR**GREGKKVILNIGPANQSH*PY*NII*L WTLQSCLCPAFTPGV*MKYWMKFAWIALEC*NP TAPYRLASCQEEAICH*CCRVIISLLVNCHMGKQ K*EGSCQRLRE*ERELTECPVPSPHSISCLSFL WQIL**V*PMQLLLVII*RRVLPGHLDQAPQTF LRQGVPLQLPVILCKDRLNKLLHLSFPLGLMLIT LALTLLLLLLYIPVS**MKVGVS*LLCTVLCCQ TYWDWINLGLPFWRCWPEDGKIDAWR*EKPRRP CFWRN*EELSRQAGRKPLMPGLLTYLST*TTSYH LESHQKPRRLSPRLLMPQGLKQKSRRKSMTLLT MTSPLVAYQVSHK*KKFLHLTRKDGSKLPLLFY LE**ELNLVLKLNLLNY*PDLEALAKFLRDSG*L VVDPTTRWPDILARH*RFFCYSLQAPNFLHTAL SEEQPLI*LDVGSLFGSLTWMCPLF*WGFSNFV PMPRNNLPTSQWGCL*AQQLTRPALRGMPSRSLP PPDHPPSSPP*PKRYTDIRLLQQIPNHSRICTQ QLLHELKGKF*ESLKFLLKRCPQMLWIFSWRLW TSLCTALKDL*LKRKVFKNVSQPSAGSTWSAIMS GITE*QLELAMVQWPCTTSGLENVRQSMDTRDQ SLQWLLLLMEDILPPTQTLTATFLFGR*TRHCW EASAC*TRHLSCAALKPTRCPLCSPRPPAPTMPS SWPGSSGLPTATSSSWPMTGRSTASWSNAAACR RDCVLVL*IIQADVALSFLTPDCSQGPAHPSAI QWHGRVLSLVHASQGQNPLVPSVDSEARTHALQD VAILSPGSFSLPEMAGESQWFLGTLLLLGATEA QKSINTVIALPAQISIFSHLNRTSEVLLESGRS DTGC*GHVAVLTIEIIAL*IT*NIVYQKDSVFTC SFLLVIARKLLNPIS*GLATTFFINS*PI*DS* LIMYTKIFSL*KIVFQTLSLLKCSSLA*MIVYL VV*NKNNHSL*SS*CNYPVTVTNLLKGLL**RAK FRSIACTENEDSPIYCYRSC*RKSLPLSPGKLA IL*FPYVWHMSVMKLL*FSLQTTTDQLKES**G ISFKQVFWKSNNYGTNVQECI*KYVGSRFI*ANI AMRVFIMLLSKL*LDHFLLMSDCAGSSS***KK *NYILYELFLTNLDLYILVRGCLVA*LLIGWLV GQNHLLHAKIENYLLNSEKICEVYKGTKMIMGEF SLKSLGCQSLSDIQKSRIKV*EQTLVISLKQIF KEHIKKLRPLDHLFHNDMMLFPLTANLYCSLVL ELGILSKVNLGTCMYIVFIKIIYVVSKEETKTYT V*TLFVW*TCCCVWHS*RNVR*KAHFVFQWVQS LLYTQHMFTL*T*MEINLL*TTSLFGMMR*MYT LAFSLTKMFCVSGKRCESGRQPAANTRMAPPATK VENKARGPRGAIALGHKRG*AFHVFRLHRQPRP VESYGCKTLGWTMFDD*TVISNY*TNICILVNI NLSLAILIATVPNFIPA*ISQH*GKLCIVIPAYT FNVLLISLALYLDLSLYM*RHMWLHW*FTSKR* HDVTPV*KCDD*TPCVQRVN*NVCLSRHFLMIP LNRLYVC*MFLCTYVC*IKQLY*RLFF