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Sequences

Sequence NM_147204

CCGGCCGGGATTCAGGAAGCGCGGATCTCCCGGCCGCCGGCGCCCAGCCGTCCCGGAGGCTGAGCAGTGCAGACGGGCCTGGGGCAGGCATGGCGGATTC CAGCGAAGGCCCCCGCGCGGGGCCCGGGGAGGTGGCTGAGCTCCCCGGGGATGAGAGTGGCACCCCAGGTGGGGAGGCTTTTCCTCTCTCCTCCCTGGCC AATCTGTTTGAGGGGGAGGATGGCTCCCTTTCGCCCTCACCGGCTGATGCCAGTCGCCCTGCTGGCCCAGGCGATGGGCGACCAAATCTGCGCATGAAGT TCCAGGGCGCCTTCCGCAAGGGGGTGCCCAACCCCATCGATCTGCTGGAGTCCACCCTATATGAGTCCTCGGTGGTGCCTGGGCCCAAGAAAGCACCCAT GGACTCACTGTTTGACTACGGCACCTATCGTCACCACTCCAGTGACAACAAGAGGTGGAGGAAGAAGATCATAGAGAAGCAGCCGCAGAGCCCCAAAGCC CCTGCCCCTCAGCCGCCCCCCATCCTCAAAGTCTTCAACCGGCCTATCCTCTTTGACATCGTGTCCCGGGGCTCCACTGCTGACCTGGACGGGCTGCTCC CATTCTTGCTGACCCACAAGAAACGCCTAACTGATGAGGAGTTTCGAGAGCCATCTACGGGGAAGACCTGCCTGCCCAAGGCCTTGCTGAACCTGAGCAA TGGCCGCAACGACACCATCCCTGTGCTGCTGGACATCGCGGAGCGCACCGGCAACATGAGGGAGTTCATTAACTCGCCCTTCCGTGACATCTACTATCGA GGTCAGACAGCCCTGCACATCGCCATTGAGCGTCGCTGCAAACACTACGTGGAACTTCTCGTGGCCCAGGGAGCTGATGTCCACGCCCAGGCCCGTGGGC GCTTCTTCCAGCCCAAGGATGAGGGGGGCTACTTCTACTTTGGGGAGCTGCCCCTGTCGCTGGCTGCCTGCACCAACCAGCCCCACATTGTCAACTACCT GACGGAGAACCCCCACAAGAAGGCGGACATGCGGCGCCAGGACTCGCGAGGCAACACAGTGCTGCATGCGCTGGTGGCCATTGCTGACAACACCCGTGAG AACACCAAGTTTGTTACCAAGATGTACGACCTGCTGCTGCTCAAGTGTGCCCGCCTCTTCCCCGACAGCAACCTGGAGGCCGTGCTCAACAACGACGGCC TCTCGCCCCTCATGATGGCTGCCAAGACGGGCAAGATTGGGAACCGCCACGAGATGCTGGCTGTGGAGCCCATCAATGAACTGCTGCGGGACAAGTGGCG CAAGTTCGGGGCCGTCTCCTTCTACATCAACGTGGTCTCCTACCTGTGTGCCATGGTCATCTTCACTCTCACCGCCTACTACCAGCCGCTGGAGGGCACA CCGCCGTACCCTTACCGCACCACGGTGGACTACCTGCGGCTGGCTGGCGAGGTCATTACGCTCTTCACTGGGGTCCTGTTCTTCTTCACCAACATCAAAG ACTTGTTCATGAAGAAATGCCCTGGAGTGAATTCTCTCTTCATTGATGGCTCCTTCCAGCTGCTCTACTTCATCTACTCTGTCCTGGTGATCGTCTCAGC AGCCCTCTACCTGGCAGGGATCGAGGCCTACCTGGCCGTGATGGTCTTTGCCCTGGTCCTGGGCTGGATGAATGCCCTTTACTTCACCCGTGGGCTGAAG CTGACGGGGACCTATAGCATCATGATCCAGAAGATTCTCTTCAAGGACCTTTTCCGATTCCTGCTCGTCTACTTGCTCTTCATGATCGGCTACGCTTCAG CCCTGGTCTCCCTCCTGAACCCGTGTGCCAACATGAAGGTGTGCAATGAGGACCAGACCAACTGCACAGTGCCCACTTACCCCTCGTGCCGTGACAGCGA GACCTTCAGCACCTTCCTCCTGGACCTGTTTAAGCTGACCATCGGCATGGGCGACCTGGAGATGCTGAGCAGCACCAAGTACCCCGTGGTCTTCATCATC CTGCTGGTGACCTACATCATCCTCACCTTTGTGCTGCTCCTCAACATGCTCATTGCCCTCATGGGCGAGACAGTGGGCCAGGTCTCCAAGGAGAGCAAGC ACATCTGGAAGCTGCAGTGGGCCACCACCATCCTGGACATTGAGCGCTCCTTCCCCGTATTCCTGAGGAAGGCCTTCCGCTCTGGGGAGATGGTCACCGT GGGCAAGAGCTCGGACGGCACTCCTGACCGCAGGTGGTGCTTCAGGGTGGATGAGGTGAACTGGTCTCACTGGAACCAGAACTTGGGCATCATCAACGAG GACCCGGGCAAGAATGAGACCTACCAGTATTATGGCTTCTCGCATACCGTGGGCCGCCTCCGCAGGGATCGCTGGTCCTCGGTGGTACCCCGCGTGGTGG AACTGAACAAGAACTCGAACCCGGACGAGGTGGTGGTGCCTCTGGACAGCATGGGGAACCCCCGCTGCGATGGCCACCAGCAGGGTTACCCCCGCAAGTG GAGGACTGATGACGCCCCGCTCTAGGGACTGCAGCCCAGCCCCAGCTTCTCTGCCCACTCATTTCTAGTCCAGCCGCATTTCAGCAGTGCCTTCTGGGGT GTCCCCCCACACCCTGCTTTGGCCCCAGAGGCGAGGGACCAGTGGAGGTGCCAGGGAGGCCCCAGGACCCTGTGGTCCCCTGGCTCTGCCTCCCCACCCT GGGGTGGGGGCTCCCGGCCACCTGTCTTGCTCCTATGGAGTCACATAAGCCAACGCCAGAGCCCCTCCACCTCAGGCCCCAGCCCCTGCCTCTCCATTAT TTATTTGCTCTGCTCTCAGGAAGCGACGTGACCCCTGCCCCAGCTGGAACCTGGCAGAGGCCTTAGGACCCCGTTCCAAGTGCACTGCCCGGCCAAGCCC CAGCCTCAGCCTGCGCCTGAGCTGCATGCGCCACCATTTTTGGCAGCGTGGCAGCTTTGCAAGGGGCTGGGGCCCTCGGCGTGGGGCCATGCCTTCTGTG TGTTCTGTAGTGTCTGGGATTTGCCGGTGCTCAATAAATGTTTATTCATTGACGGTG

refseq_TRPV4.F2 (forward primer)
refseq_TRPV4.R2 (reverse primer)
Single exon skipping

Frame 0

PAGIQEARISRPPAPSRPGG*AVQTGLGQAWRI PAKAPARGPGRWLSSPGMRVAPQVGRLFLSPPWP ICLRGRMAPFRPHRLMPVALLAQAMGDQICA*S SRAPSARGCPTPSICWSPPYMSPRWCLGPRKHP WTHCLTTAPIVTTPVTTRGGGRRS*RSSRRAPKP LPLSRPPSSKSSTGLSSLTSCPGAPLLTWTGCS HSC*PTRNA*LMRSFESHLRGRPACPRPC*T*A MAATTPSLCCWTSRSAPAT*GSSLTRPSVTSTIE VRQPCTSPLSVAANTTWNFSWPRELMSTPRPVG ASSSPRMRGATSTLGSCPCRWLPAPTSPTLSTT *RRTPTRRRTCGARTREATQCCMRWWPLLTTPVR TPSLLPRCTTCCCSSVPASSPTATWRPCSTTTA SRPS*WLPRRARLGTATRCWLWSPSMNCCGTSG ASSGPSPSTSTWSPTCVPWSSSLSPPTTSRWRAH RRTLTAPRWTTCGWLARSLRSSLGSCSSSPTSK TCS*RNALE*ILSSLMAPSSCSTSSTLSW*SSQ QPSTWQGSRPTWP*WSLPWSWAG*MPFTSPVG*S *RGPIAS*SRRFSSRTFSDSCSSTCSS*SATLQ PWSPS*TRVPT*RCAMRTRPTAQCPLTPRAVTA RPSAPSSWTCLS*PSAWATWRC*AAPSTPWSSSS CW*PTSSSPLCCSSTCSLPSWARQWARSPRRAS TSGSCSGPPPSWTLSAPSPYS*GRPSALGRWSP WARARTALLTAGGASGWMR*TGLTGTRTWASSTR TRARMRPTSIMASRIPWAASAGIAGPRWYPAWW N*TRTRTRTRWWCLWTAWGTPAAMATSRVTPAS GGLMTPRSRDCSPAPASLPTHF*SSRISAVPSGV SPHTLLWPQRRGTSGGAREAPGPCGPLALPPHP GVGAPGHLSCSYGVT*ANARAPPPQAPAPASPL FICSALRKRRDPCPSWNLAEALGPRSKCTARPSP SLSLRLSCMRHHFWQRGSFARGWGPRRGAMPSV CSVVSGICRCSINVYSLTV

Frame 1

RPGFRKRGSPGRRRPAVPEAEQCRRAWGRHGGF QRRPPRGARGGG*APRG*EWHPRWGGFSSLLPG QSV*GGGWLPFALTG*CQSPCWPRRWATKSAHEV PGRLPQGGAQPHRSAGVHPI*VLGGAWAQESTH GLTV*LRHLSSPLQ*QQEVEEEDHREAAAEPQS PCPSAAPHPQSLQPAYPL*HRVPGLHC*PGRAAP ILADPQETPN**GVSRAIYGEDLPAQGLAEPEQ WPQRHHPCAAGHRGAHRQHEGVH*LALP*HLLS RSDSPAHRH*ASLQTLRGTSRGPGS*CPRPGPWA LLPAQG*GGLLLLWGAAPVAGCLHQPAPHCQLP DGEPPQEGGHAAPGLARQHSAACAGGHC*QHP* EHQVCYQDVRPAAAQVCPPLPRQQPGGRAQQRRP LAPHDGCQDGQDWEPPRDAGCGAHQ*TAAGQVA QVRGRLLLHQRGLLPVCHGHLHSHRLLPAAGGH TAVPLPHHGGLPAAGWRGHYALHWGPVLLHQHQR LVHEEMPWSEFSLH*WLLPAALLHLLCPGDRLS SPLPGRDRGLPGRDGLCPGPGLDECPLLHPWAE ADGDL*HHDPEDSLQGPFPIPARLLALHDRLRFS PGLPPEPVCQHEGVQ*GPDQLHSAHLPLVP*QR DLQHLPPGPV*ADHRHGRPGDAEQHQVPRGLHH PAGDLHHPHLCAAPQHAHCPHGRDSGPGLQGEQA HLEAAVGHHHPGH*ALLPRIPEEGLPLWGDGHR GQELGRHS*PQVVLQGG*GELVSLEPELGHHQR GPGQE*DLPVLWLLAYRGPPPQGSLVLGGTPRGG TEQELEPGRGGGASGQHGEPPLRWPPAGLPPQV ED**RPALGTAAQPQLLCPLISSPAAFQQCLLG CPPTPCFGPRGEGPVEVPGRPQDPVVPWLCLPTL GWGLPATCLAPMESHKPTPEPLHLRPQPLPLHY LFALLSGSDVTPAPAGTWQRP*DPVPSALPGQA PASACA*AACATIFGSVAALQGAGALGVGPCLLC VL*CLGFAGAQ*MFIH*R

Frame 2

GRDSGSADLPAAGAQPSRRLSSADGPGAGMADS SEGPRAGPGEVAELPGDESGTPGGEAFPLSSLA NLFEGEDGSLSPSPADASRPAGPGDGRPNLRMK FQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPM DSLFDYGTYRHHSSDNKRWRKKIIEKQPQSPKA PAPQPPPILKVFNRPILFDIVSRGSTADLDGLL PFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSN GRNDTIPVLLDIAERTGNMREFINSPFRDIYYR GQTALHIAIERRCKHYVELLVAQGADVHAQARG RFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYL TENPHKKADMRRQDSRGNTVLHALVAIADNTRE NTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDG LSPLMMAAKTGKIGNRHEMLAVEPINELLRDKWR KFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGT PPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIK DLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSA ALYLAGIEAYLAVMVFALVLGWMNALYFTRGLK LTGTYSIMIQKILFKDLFRFLLVYLLFMIGYAS ALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSE TFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFII LLVTYIILTFVLLLNMLIALMGETVGQVSKESK HIWKLQWATTILDIERSFPVFLRKAFRSGEMVTV GKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINE DPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVV ELNKNSNPDEVVVPLDSMGNPRCDGHQQGYPRKW RTDDAPL*GLQPSPSFSAHSFLVQPHFSSAFWG VPPHPALAPEARDQWRCQGGPRTLWSPGSASPP WGGGSRPPVLLLWSHISQRQSPSTSGPSPCLSII YLLCSQEAT*PLPQLEPGRGLRTPFQVHCPAKP QPQPAPELHAPPFLAAWQLCKGLGPSAWGHAFC VFCSVWDLPVLNKCLFIDG

Sequence NM_021625

CCGGCCGGGATTCAGGAAGCGCGGATCTCCCGGCCGCCGGCGCCCAGCCGTCCCGGAGGCTGAGCAGTGCAGACGGGCCTGGGGCAGGCATGGCGGATTC CAGCGAAGGCCCCCGCGCGGGGCCCGGGGAGGTGGCTGAGCTCCCCGGGGATGAGAGTGGCACCCCAGGTGGGGAGGCTTTTCCTCTCTCCTCCCTGGCC AATCTGTTTGAGGGGGAGGATGGCTCCCTTTCGCCCTCACCGGCTGATGCCAGTCGCCCTGCTGGCCCAGGCGATGGGCGACCAAATCTGCGCATGAAGT TCCAGGGCGCCTTCCGCAAGGGGGTGCCCAACCCCATCGATCTGCTGGAGTCCACCCTATATGAGTCCTCGGTGGTGCCTGGGCCCAAGAAAGCACCCAT GGACTCACTGTTTGACTACGGCACCTATCGTCACCACTCCAGTGACAACAAGAGGTGGAGGAAGAAGATCATAGAGAAGCAGCCGCAGAGCCCCAAAGCC CCTGCCCCTCAGCCGCCCCCCATCCTCAAAGTCTTCAACCGGCCTATCCTCTTTGACATCGTGTCCCGGGGCTCCACTGCTGACCTGGACGGGCTGCTCC CATTCTTGCTGACCCACAAGAAACGCCTAACTGATGAGGAGTTTCGAGAGCCATCTACGGGGAAGACCTGCCTGCCCAAGGCCTTGCTGAACCTGAGCAA TGGCCGCAACGACACCATCCCTGTGCTGCTGGACATCGCGGAGCGCACCGGCAACATGAGGGAGTTCATTAACTCGCCCTTCCGTGACATCTACTATCGA GGTCAGACAGCCCTGCACATCGCCATTGAGCGTCGCTGCAAACACTACGTGGAACTTCTCGTGGCCCAGGGAGCTGATGTCCACGCCCAGGCCCGTGGGC GCTTCTTCCAGCCCAAGGATGAGGGGGGCTACTTCTACTTTGGGGAGCTGCCCCTGTCGCTGGCTGCCTGCACCAACCAGCCCCACATTGTCAACTACCT GACGGAGAACCCCCACAAGAAGGCGGACATGCGGCGCCAGGACTCGCGAGGCAACACAGTGCTGCATGCGCTGGTGGCCATTGCTGACAACACCCGTGAG AACACCAAGTTTGTTACCAAGATGTACGACCTGCTGCTGCTCAAGTGTGCCCGCCTCTTCCCCGACAGCAACCTGGAGGCCGTGCTCAACAACGACGGCC TCTCGCCCCTCATGATGGCTGCCAAGACGGGCAAGATTGGGATCTTTCAGCACATCATCCGGCGGGAGGTGACGGATGAGGACACACGGCACCTGTCCCG CAAGTTCAAGGACTGGGCCTATGGGCCAGTGTATTCCTCGCTTTATGACCTCTCCTCCCTGGACACGTGTGGGGAAGAGGCCTCCGTGCTGGAGATCCTG GTGTACAACAGCAAGATTGAGAACCGCCACGAGATGCTGGCTGTGGAGCCCATCAATGAACTGCTGCGGGACAAGTGGCGCAAGTTCGGGGCCGTCTCCT TCTACATCAACGTGGTCTCCTACCTGTGTGCCATGGTCATCTTCACTCTCACCGCCTACTACCAGCCGCTGGAGGGCACACCGCCGTACCCTTACCGCAC CACGGTGGACTACCTGCGGCTGGCTGGCGAGGTCATTACGCTCTTCACTGGGGTCCTGTTCTTCTTCACCAACATCAAAGACTTGTTCATGAAGAAATGC CCTGGAGTGAATTCTCTCTTCATTGATGGCTCCTTCCAGCTGCTCTACTTCATCTACTCTGTCCTGGTGATCGTCTCAGCAGCCCTCTACCTGGCAGGGA TCGAGGCCTACCTGGCCGTGATGGTCTTTGCCCTGGTCCTGGGCTGGATGAATGCCCTTTACTTCACCCGTGGGCTGAAGCTGACGGGGACCTATAGCAT CATGATCCAGAAGATTCTCTTCAAGGACCTTTTCCGATTCCTGCTCGTCTACTTGCTCTTCATGATCGGCTACGCTTCAGCCCTGGTCTCCCTCCTGAAC CCGTGTGCCAACATGAAGGTGTGCAATGAGGACCAGACCAACTGCACAGTGCCCACTTACCCCTCGTGCCGTGACAGCGAGACCTTCAGCACCTTCCTCC TGGACCTGTTTAAGCTGACCATCGGCATGGGCGACCTGGAGATGCTGAGCAGCACCAAGTACCCCGTGGTCTTCATCATCCTGCTGGTGACCTACATCAT CCTCACCTTTGTGCTGCTCCTCAACATGCTCATTGCCCTCATGGGCGAGACAGTGGGCCAGGTCTCCAAGGAGAGCAAGCACATCTGGAAGCTGCAGTGG GCCACCACCATCCTGGACATTGAGCGCTCCTTCCCCGTATTCCTGAGGAAGGCCTTCCGCTCTGGGGAGATGGTCACCGTGGGCAAGAGCTCGGACGGCA CTCCTGACCGCAGGTGGTGCTTCAGGGTGGATGAGGTGAACTGGTCTCACTGGAACCAGAACTTGGGCATCATCAACGAGGACCCGGGCAAGAATGAGAC CTACCAGTATTATGGCTTCTCGCATACCGTGGGCCGCCTCCGCAGGGATCGCTGGTCCTCGGTGGTACCCCGCGTGGTGGAACTGAACAAGAACTCGAAC CCGGACGAGGTGGTGGTGCCTCTGGACAGCATGGGGAACCCCCGCTGCGATGGCCACCAGCAGGGTTACCCCCGCAAGTGGAGGACTGATGACGCCCCGC TCTAGGGACTGCAGCCCAGCCCCAGCTTCTCTGCCCACTCATTTCTAGTCCAGCCGCATTTCAGCAGTGCCTTCTGGGGTGTCCCCCCACACCCTGCTTT GGCCCCAGAGGCGAGGGACCAGTGGAGGTGCCAGGGAGGCCCCAGGACCCTGTGGTCCCCTGGCTCTGCCTCCCCACCCTGGGGTGGGGGCTCCCGGCCA CCTGTCTTGCTCCTATGGAGTCACATAAGCCAACGCCAGAGCCCCTCCACCTCAGGCCCCAGCCCCTGCCTCTCCATTATTTATTTGCTCTGCTCTCAGG AAGCGACGTGACCCCTGCCCCAGCTGGAACCTGGCAGAGGCCTTAGGACCCCGTTCCAAGTGCACTGCCCGGCCAAGCCCCAGCCTCAGCCTGCGCCTGA GCTGCATGCGCCACCATTTTTGGCAGCGTGGCAGCTTTGCAAGGGGCTGGGGCCCTCGGCGTGGGGCCATGCCTTCTGTGTGTTCTGTAGTGTCTGGGAT TTGCCGGTGCTCAATAAATGTTTATTCATTGACGGTG

refseq_TRPV4.F2 (forward primer)
refseq_TRPV4.R2 (reverse primer)
Single exon skipping

Frame 0

PAGIQEARISRPPAPSRPGG*AVQTGLGQAWRI PAKAPARGPGRWLSSPGMRVAPQVGRLFLSPPWP ICLRGRMAPFRPHRLMPVALLAQAMGDQICA*S SRAPSARGCPTPSICWSPPYMSPRWCLGPRKHP WTHCLTTAPIVTTPVTTRGGGRRS*RSSRRAPKP LPLSRPPSSKSSTGLSSLTSCPGAPLLTWTGCS HSC*PTRNA*LMRSFESHLRGRPACPRPC*T*A MAATTPSLCCWTSRSAPAT*GSSLTRPSVTSTIE VRQPCTSPLSVAANTTWNFSWPRELMSTPRPVG ASSSPRMRGATSTLGSCPCRWLPAPTSPTLSTT *RRTPTRRRTCGARTREATQCCMRWWPLLTTPVR TPSLLPRCTTCCCSSVPASSPTATWRPCSTTTA SRPS*WLPRRARLGSFSTSSGGR*RMRTHGTCP ASSRTGPMGQCIPRFMTSPPWTRVGKRPPCWRSW CTTARLRTATRCWLWSPSMNCCGTSGASSGPSP STSTWSPTCVPWSSSLSPPTTSRWRAHRRTLTA PRWTTCGWLARSLRSSLGSCSSSPTSKTCS*RNA LE*ILSSLMAPSSCSTSSTLSW*SSQQPSTWQG SRPTWP*WSLPWSWAG*MPFTSPVG*S*RGPIA S*SRRFSSRTFSDSCSSTCSS*SATLQPWSPS*T RVPT*RCAMRTRPTAQCPLTPRAVTARPSAPSS WTCLS*PSAWATWRC*AAPSTPWSSSSCW*PTS SSPLCCSSTCSLPSWARQWARSPRRASTSGSCSG PPPSWTLSAPSPYS*GRPSALGRWSPWARARTA LLTAGGASGWMR*TGLTGTRTWASSTRTRARMR PTSIMASRIPWAASAGIAGPRWYPAWWN*TRTRT RTRWWCLWTAWGTPAAMATSRVTPASGGLMTPR SRDCSPAPASLPTHF*SSRISAVPSGVSPHTLL WPQRRGTSGGAREAPGPCGPLALPPHPGVGAPGH LSCSYGVT*ANARAPPPQAPAPASPLFICSALR KRRDPCPSWNLAEALGPRSKCTARPSPSLSLRL SCMRHHFWQRGSFARGWGPRRGAMPSVCSVVSGI CRCSINVYSLTV

Frame 1

RPGFRKRGSPGRRRPAVPEAEQCRRAWGRHGGF QRRPPRGARGGG*APRG*EWHPRWGGFSSLLPG QSV*GGGWLPFALTG*CQSPCWPRRWATKSAHEV PGRLPQGGAQPHRSAGVHPI*VLGGAWAQESTH GLTV*LRHLSSPLQ*QQEVEEEDHREAAAEPQS PCPSAAPHPQSLQPAYPL*HRVPGLHC*PGRAAP ILADPQETPN**GVSRAIYGEDLPAQGLAEPEQ WPQRHHPCAAGHRGAHRQHEGVH*LALP*HLLS RSDSPAHRH*ASLQTLRGTSRGPGS*CPRPGPWA LLPAQG*GGLLLLWGAAPVAGCLHQPAPHCQLP DGEPPQEGGHAAPGLARQHSAACAGGHC*QHP* EHQVCYQDVRPAAAQVCPPLPRQQPGGRAQQRRP LAPHDGCQDGQDWDLSAHHPAGGDG*GHTAPVP QVQGLGLWASVFLAL*PLLPGHVWGRGLRAGDP GVQQQD*EPPRDAGCGAHQ*TAAGQVAQVRGRLL LHQRGLLPVCHGHLHSHRLLPAAGGHTAVPLPH HGGLPAAGWRGHYALHWGPVLLHQHQRLVHEEM PWSEFSLH*WLLPAALLHLLCPGDRLSSPLPGRD RGLPGRDGLCPGPGLDECPLLHPWAEADGDL*H HDPEDSLQGPFPIPARLLALHDRLRFSPGLPPE PVCQHEGVQ*GPDQLHSAHLPLVP*QRDLQHLPP GPV*ADHRHGRPGDAEQHQVPRGLHHPAGDLHH PHLCAAPQHAHCPHGRDSGPGLQGEQAHLEAAV GHHHPGH*ALLPRIPEEGLPLWGDGHRGQELGRH S*PQVVLQGG*GELVSLEPELGHHQRGPGQE*D LPVLWLLAYRGPPPQGSLVLGGTPRGGTEQELE PGRGGGASGQHGEPPLRWPPAGLPPQVED**RPA LGTAAQPQLLCPLISSPAAFQQCLLGCPPTPCF GPRGEGPVEVPGRPQDPVVPWLCLPTLGWGLPA TCLAPMESHKPTPEPLHLRPQPLPLHYLFALLSG SDVTPAPAGTWQRP*DPVPSALPGQAPASACA* AACATIFGSVAALQGAGALGVGPCLLCVL*CLG FAGAQ*MFIH*R

Frame 2

GRDSGSADLPAAGAQPSRRLSSADGPGAGMADS SEGPRAGPGEVAELPGDESGTPGGEAFPLSSLA NLFEGEDGSLSPSPADASRPAGPGDGRPNLRMK FQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPM DSLFDYGTYRHHSSDNKRWRKKIIEKQPQSPKA PAPQPPPILKVFNRPILFDIVSRGSTADLDGLL PFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSN GRNDTIPVLLDIAERTGNMREFINSPFRDIYYR GQTALHIAIERRCKHYVELLVAQGADVHAQARG RFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYL TENPHKKADMRRQDSRGNTVLHALVAIADNTRE NTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDG LSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSR KFKDWAYGPVYSSLYDLSSLDTCGEEASVLEIL VYNSKIENRHEMLAVEPINELLRDKWRKFGAVS FYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRT TVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKC PGVNSLFIDGSFQLLYFIYSVLVIVSAALYLAG IEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSI MIQKILFKDLFRFLLVYLLFMIGYASALVSLLN PCANMKVCNEDQTNCTVPTYPSCRDSETFSTFL LDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYII LTFVLLLNMLIALMGETVGQVSKESKHIWKLQW ATTILDIERSFPVFLRKAFRSGEMVTVGKSSDG TPDRRWCFRVDEVNWSHWNQNLGIINEDPGKNET YQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSN PDEVVVPLDSMGNPRCDGHQQGYPRKWRTDDAP L*GLQPSPSFSAHSFLVQPHFSSAFWGVPPHPAL APEARDQWRCQGGPRTLWSPGSASPPWGGGSRP PVLLLWSHISQRQSPSTSGPSPCLSIIYLLCSQ EAT*PLPQLEPGRGLRTPFQVHCPAKPQPQPAPE LHAPPFLAAWQLCKGLGPSAWGHAFCVFCSVWD LPVLNKCLFIDG