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Sequences

Sequence NM_001007471

TCCGACCACAGGCTGTTTTGTGCAGGCTGTCCCTCTTCTTCAAAATCGTGCATCCCCTCCCCGAAGCAGCAGGCAGTGTGCCTCCATTCAGCCACATTTG
GTATGCATGAGCACGGCTGCAGAGAGAGGGGAGGTGGCTGTTTTAAGAAGGTTCAGGGGCTCAGGCAAGGCTACTTGACTAGTCTTCCAAGTTCCAGGAA
GCCTCTGCCCTAATGGAATTTGCAGGTGTGGAGATGACCATGGGATGCCAGAGCCGTGGGGGACCGTTTATTTTCTAGGCATTGCTCAGGTTTTCAGTTT
CTTGTTTTCCTGGTGGAATTTGGAAGGGGTCATGAATCAGGCTGATGCTCCTCGACCCCTAAACTGGACCATCCGGAAGCTGTGCCACGCAGCCTTTCTT
CCATCTGTCAGACTTCTGAAGGCTCAGAAATCCTGGATAGAAAGAGCATTTTATAAAAGAGAATGTGTCCACATCATACCCAGCACCAAAGACCCCCATA
GGTGTTGCTGTGGGCGTCTGATAGGCCAGCATGTTGGCCTCACCCCCAGTATCTCCGTGCTTCAGAATGAGAAAAATGAAAGTCGCCTCTCCCGAAATGA
CATCCAGTCTGAAAAGTGGTCCATCAGCAAACACACTCAACTCAGCCCTACGGATGCTTTTGGGACCATTGAGTTCCAAGGAGGTGGCCATTCCAACAAA
GCCATGTATGTGCGAGTATCTTTTGATACAAAACCTGATCTCCTCTTACACCTGATGACCAAGGAATGGCAGTTGGAGCTTCCCAAGCTTCTCATCTCTG
TCCATGGGGGCCTGCAGAACTTTGAACTCCAGCCAAAACTCAAGCAAGTCTTTGGGAAAGGGCTCATCAAAGCAGCAATGACAACTGGAGCGTGGATATT
CACTGGAGGGGTTAACACAGGTGTTATTCGTCATGTTGGCGATGCCTTGAAGGATCATGCCTCTAAGTCTCGAGGAAAGATATGCACCATAGGTATTGCC
CCCTGGGGAATTGTGGAAAACCAGGAGGACCTCATTGGAAGAGATGTTGTCCGGCCATACCAGACCATGTCCAATCCCATGAGCAAGCTCACTGTTCTCA
ACAGCATGCATTCCCACTTCATTCTGGCTGACAACGGGACCACTGGAAAATATGGAGCAGAGGTGAAACTTCGAAGACAACTGGAAAAGCATATTTCACT
CCAGAAGATAAACACAAGAATCGGTCAAGGTGTTCCTGTGGTGGCACTCATAGTGGAAGGAGGACCCAATGTGATCTCGATTGTTTTGGAGTACCTTCGA
GACACCCCTCCCGTGCCAGTGGTTGTCTGTGATGGGAGTGGACGGGCATCGGACATCCTGGCCTTTGGGCATAAATACTCAGAAGAAGGCGGACTGATAA
ATGAATCTTTGAGGGACCAGCTGTTGGTGACTATACAGAAGACTTTCACATACACTCGAACCCAAGCTCAGCATCTGTTCATCATCCTCATGGAGTGCAT
GAAGAAGAAGGAATTGATTACGGTATTTCGGATGGGATCAGAAGGACACCAGGACATTGATTTGGCTATCCTGACAGCTTTACTCAAAGGAGCCAATGCC
TCGGCCCCAGACCAACTGAGCTTAGCTTTAGCCTGGAACAGAGTCGACATCGCTCGCAGCCAGATCTTTATTTACGGGCAACAGTGGCCGGTGGGATCTC
TGGAGCAAGCCATGTTGGATGCCTTAGTTCTGGACAGAGTGGATTTTGTGAAATTACTCATAGAGAATGGAGTAAGCATGCACCGTTTTCTCACCATCTC
CAGACTAGAGGAATTGTACAATACGAGACATGGGCCCTCAAATACATTGTACCACTTGGTCAGGGATGTCAAAAAGGGGAACCTGCCCCCAGACTACAGA
ATCAGCCTGATTGACATCGGCCTGGTGATCGAGTACCTGATGGGCGGGGCTTATCGCTGCAACTACACGCGCAAGCGCTTCCGGACCCTCTACCACAACC
TCTTCGGCCCCAAGAGGCCCAAAGCCTTGAAACTGCTGGGAATGGAGGATGATATTCCCTTGAGGCGAGGAAGAAAGACAACCAAGAAACGTGAAGAAGA
GGTGGACATTGACTTGGATGATCCTGAGATCAACCACTTCCCCTTCCCTTTCCATGAGCTCATGGTGTGGGCTGTTCTCATGAAGCGGCAGAAGATGGCC
CTGTTCTTCTGGCAGCACGGTGAGGAGGCCATGGCCAAGGCCCTGGTGGCCTGCAAGCTCTGCAAAGCCATGGCTCATGAGGCCTCTGAGAACGACATGG
TTGACGACATTTCCCAGGAGCTGAATCACAATTCCAGAGACTTTGGCCAGCTGGCTGTGGAGCTCCTGGACCAGTCCTACAAGCAGGACGAACAGCTGGC
CATGAAACTGCTGACGTATGAGCTGAAGAACTGGAGCAACGCCACGTGCCTGCAGCTTGCCGTGGCTGCCAAACACCGCGACTTCATCGCGCACACGTGC
AGCCAGATGCTGCTCACCGACATGTGGATGGGCCGGCTCCGCATGCGCAAGAACTCAGGCCTCAAGGTAATTCTGGGAATTCTACTTCCTCCTTCAATTC
TCAGCTTGGAGTTCAAGAACAAAGACGACATGCCCTATATGTCTCAGGCCCAGGAAATCCACCTCCAAGAGAAGGAGGCAGAAGAACCAGAGAAGCCCAC
AAAGGAAAAAGAGGAAGAGGACATGGAGCTCACAGCAATGTTGGGACGAAACAACGGGGAGTCCTCCAGGAAGAAGGATGAAGAGGAAGTTCAGAGCAAG
CACCGGTTAATCCCCCTCGGCAGAAAAATCTATGAATTCTACAATGCACCCATCGTGAAGTTCTGGTTCTACACACTGGCGTATATCGGATACCTGATGC
TCTTCAACTATATCGTGTTAGTGAAGATGGAACGCTGGCCGTCCACCCAGGAATGGATCGTAATCTCCTATATTTTCACCCTGGGAATAGAAAAGATGAG
AGAGATTCTGATGTCAGAGCCAGGGAAGTTGCTACAGAAAGTGAAGGTATGGCTGCAGGAGTACTGGAATGTCACGGACCTCATCGCCATCCTTCTGTTT
TCTGTCGGAATGATCCTTCGTCTCCAAGACCAGCCCTTCAGGAGTGACGGGAGGGTCATCTACTGCGTGAACATCATTTACTGGTATATCCGTCTCCTAG
ACATCTTCGGCGTGAACAAGTATTTGGGCCCGTATGTAATGATGATTGGAAAAATGATGATAGACATGATGTACTTTGTCATCATTATGCTGGTGGTTCT
GATGAGCTTTGGGGTCGCCAGGCAAGCCATCCTTTTTCCCAATGAGGAGCCATCATGGAAACTGGCCAAGAACATCTTCTACATGCCCTATTGGATGATT
TATGGGGAAGTGTTTGCGGACCAGATAGACCCTCCCTGTGGACAGAATGAGACCCGAGAGGATGGTAAAATAATCCAGCTGCCTCCCTGCAAGACAGGAG
CTTGGATCGTGCCGGCCATCATGGCCTGCTACCTCTTAGTGGCAAACATCTTGCTGGTCAACCTCCTCATTGCTGTCTTTAACAATACATTTTTTGAAGT
AAAATCGATATCCAACCAAGTCTGGAAGTTTCAGAGGTATCAGCTCATCATGACTTTCCATGAAAGGCCAGTTCTGCCCCCACCACTGATCATCTTCAGC
CACATGACCATGATATTCCAGCACCTGTGCTGCCGATGGAGGAAACACGAGAGCGACCCGGATGAAAGGGACTACGGCCTGAAACTCTTCATAACCGATG
ATGAGCTCAAGAAAGTACATGACTTTGAAGAGCAATGCATAGAAGAATACTTCAGAGAAAAGGATGATCGGTTCAACTCATCTAATGATGAGAGGATACG
GGTGACTTCAGAAAGGGTGGAGAACATGTCTATGCGGCTGGAGGAAGTCAACGAGAGAGAGCACTCCATGAAGGCTTCACTCCAGACCGTGGACATCCGG
CTGGCGCAGCTGGAAGACCTTATCGGGCGCATGGCCACGGCCCTGGAGCGCCTGACAGGTCTGGAGCGGGCCGAGTCCAACAAAATCCGCTCGAGGACCT
CGTCAGACTGCACGGACGCCGCCTACATTGTCCGTCAGAGCAGCTTCAACAGCCAGGAAGGGAACACCTTCAAGCTCCAAGAGAGTATAGACCCTGCAGG
TGAGGAGACCATGTCCCCAACTTCTCCAACCTTAATGCCCCGTATGCGAAGCCATTCTTTCTATTCGGTCAATATGAAAGACAAAGGTGGTATAGAAAAG
TTGGAAAGTATTTTTAAAGAAAGGTCCCTGAGCCTACACCGGGCTACTAGTTCCCACTCTGTAGCAAAAGAACCCAAAGCTCCTGCAGCCCCTGCCAACA
CCTTGGCCATTGTTCCTGATTCCAGAAGACCATCATCGTGTATAGACATCTATGTCTCTGCTATGGATGAGCTCCACTGTGATATAGACCCTCTGGACAA
TTCCGTGAACATCCTTGGGCTGGGCGAGCCAAGCTTTTCAACTCCAGTACCTTCCACAGCCCCTTCAAGTAGTGCCTATGCAACACTTGCACCCACAGAC
AGACCTCCAAGCCGGAGCATTGATTTTGAGGACATCACCTCCATGGACACTAGATCTTTTTCTTCAGACTACACCCACCTCCCAGAATGCCAAAACCCCT
GGGACTCAGAGCCTCCGATGTACCACACCATTGAGCGTTCCAAAAGTAGCCGCTACCTAGCCACCACACCCTTTCTTCTAGAAGAGGCTCCCATTGTGAA
ATCTCATAGCTTTATGTTTTCCCCCTCAAGGAGCTATTATGCCAACTTTGGGGTGCCTGTAAAAACAGCAGAATACACAAGTATTACAGACTGTATTGAC
ACAAGGTGTGTCAATGCCCCTCAAGCAATTGCGGACAGAGCTGCCTTCCCTGGAGGTCTTGGAGACAAAGTGGAGGACTTAACTTGCTGCCATCCAGAGC
GAGAAGCAGAACTGAGTCACCCCAGCTCTGACAGTGAGGAGAATGAGGCCAAAGGCCGCAGAGCCACCATTGCAATATCCTCCCAGGAGGGTGATAACTC
AGAGAGAACCCTGTCCAACAACATCACTGTTCCCAAGATAGAGCGCGCCAACAGCTACTCGGCAGAGGAGCCAAGTGCGCCATATGCACACACCAGGAAG
AGCTTCTCCATCAGTGACAAACTCGACAGGCAGCGGAACACAGCAAGCCTGCGAAATCCCTTCCAGAGAAGCAAGTCCTCCAAGCCGGAGGGCCGAGGGG
ACAGCCTGTCCATGAGGAGACTGTCCAGAACATCGGCTTTCCAAAGCTTTGAAAGCAAGCACAACTAAACCTTCTTAATATCCGCCACAGAAGGCTCAAG
AATCCAGCCCTAAAATTCTCTCCAACTCCAGTTTTTCCCCTTTCCTTGAATCATACCTGCTTTATTCTTAGCTGAGCAAAACAAGCAATGCTTTGGGAGG
TGTTAACTCAAAGGTGACTTCTGGGCCACAGATCAAGAAAGCATTTGATCTGACCCAGTGCCAGACACAGGGGATTTAAGGCATGTTCACACTTGCTGGG
CAGGGAGGGGGAAGAGAGGGAGAAGGAAGGGTTAGAGATGAATGTGTATCCGCAGTCACAGCAGAAAGCCATGAGAGCAGGGGAAACAAGGGGCTTCGAG
CACGCTCCATGCCAGGAGGCATCTGTTGATTTCTGACCATTATCAAGAGTTGTAGGATGCAGGGCTAAATTGCAAAATAAAATAAAATAGCCAGCGTACA
CAATGAGATATTCTAAACTTCCATTCTGTTTTCTTTTCACATTGGCTCCATCACTGGTGACTGATGAAGAGCATCCTCTTTATTCAGTATAAGCCGGCAG
CAAGCAGTTCTACCTAACGTCCCACATCCTTCTCATGCCAACACTTCTGTAATTGATCATTATAAAGAAAAAACAAGGTAACAGTCATAGTTCACCTGTC
TCTTATCTATTCACTTCTGGTGCCACAACTGTTTATCCTTTTTTGAAGAAAATAAGGGAACAGAAATGCCTTTTTGTATTGCAATCGAAATGAAAGAAGA
GTTGATGTTAAAAAAACAAAAGTCAAGTGATTTATTATATACAGTGGGCGTTCAAGTCTAGTCGAGCAAGCTCAGGAGAATGTAATTAAATAATTTTATA
TTTTTTAATTTATTTTGTATCTCACCTGTCATGGATGAATTCATTCACTGAATATGTAATATTGAACTTAAAAAAAAAAAAAAAAAAA
  • refseq_TRPM3.F6 (forward primer)
  • refseq_TRPM3.R6 (reverse primer)
  • Single exon skipping

Frame 0

SDHRLFCAGCPSSSKSCIPSPKQQAVCLHSATF
GMHEHGCRERGGGCFKKVQGLRQGYLTSLPSSRK
PLP*WNLQVWR*PWDARAVGDRLFSRHCSGFQF
LVFLVEFGRGHESG*CSSTPKLDHPEAVPRSLS
SICQTSEGSEILDRKSIL*KRMCPHHTQHQRPP*
VLLWASDRPACWPHPQYLRASE*EK*KSPLPK*
HPV*KVVHQQTHSTQPYGCFWDH*VPRRWPFQQ
SHVCASIF*YKT*SPLTPDDQGMAVGASQASHLC
PWGPAEL*TPAKTQASLWERAHQSSNDNWSVDI
HWRG*HRCYSSCWRCLEGSCL*VSRKDMHHRYC
PLGNCGKPGGPHWKRCCPAIPDHVQSHEQAHCSQ
QHAFPLHSG*QRDHWKIWSRGETSKTTGKAYFT
PEDKHKNRSRCSCGGTHSGRRTQCDLDCFGVPS
RHPSRASGCL*WEWTGIGHPGLWA*ILRRRRTDK
*IFEGPAVGDYTEDFHIHSNPSSASVHHPHGVH
EEEGIDYGISDGIRRTPGH*FGYPDSFTQRSQC
LGPRPTELSFSLEQSRHRSQPDLYLRATVAGGIS
GASHVGCLSSGQSGFCEITHREWSKHAPFSHHL
QTRGIVQYETWALKYIVPLGQGCQKGEPAPRLQ
NQPD*HRPGDRVPDGRGLSLQLHAQALPDPLPQP
LRPQEAQSLETAGNGG*YSLEARKKDNQET*RR
GGH*LG*S*DQPLPLPFP*AHGVGCSHEAAEDG
PVLLAAR*GGHGQGPGGLQALQSHGS*GL*ERHG
*RHFPGAESQFQRLWPAGCGAPGPVLQAGRTAG
HETADV*AEELEQRHVPAACRGCQTPRLHRAHV
QPDAAHRHVDGPAPHAQELRPQGNSGNSTSSFNS
QLGVQEQRRHALYVSGPGNPPPREGGRRTREAH
KGKRGRGHGAHSNVGTKQRGVLQEEG*RGSSEQ
APVNPPRQKNL*ILQCTHREVLVLHTGVYRIPDA
LQLYRVSEDGTLAVHPGMDRNLLYFHPGNRKDE
RDSDVRAREVATESEGMAAGVLECHGPHRHPSV
FCRNDPSSPRPALQE*REGHLLREHHLLVYPSPR
HLRREQVFGPVCNDDWKNDDRHDVLCHHYAGGS
DELWGRQASHPFSQ*GAIMETGQEHLLHALLDD
LWGSVCGPDRPSLWTE*DPRGW*NNPAASLQDRS
LDRAGHHGLLPLSGKHLAGQPPHCCL*QYIF*S
KIDIQPSLEVSEVSAHHDFP*KASSAPTTDHLQ
PHDHDIPAPVLPMEETRERPG*KGLRPETLHNR*
*AQEST*L*RAMHRRILQRKG*SVQLI***EDT
GDFRKGGEHVYAAGGSQRERALHEGFTPDRGHP
AGAAGRPYRAHGHGPGAPDRSGAGRVQQNPLEDL
VRLHGRRLHCPSEQLQQPGREHLQAPREYRPCR
*GDHVPNFSNLNAPYAKPFFLFGQYERQRWYRK
VGKYF*RKVPEPTPGY*FPLCSKRTQSSCSPCQH
LGHCS*FQKTIIVYRHLCLCYG*APL*YRPSGQ
FREHPWAGRAKLFNSSTFHSPFK*CLCNTCTHR
QTSKPEH*F*GHHLHGH*IFFFRLHPPPRMPKPL
GLRASDVPHH*AFQK*PLPSHHTLSSRRGSHCE
IS*LYVFPLKELLCQLWGACKNSRIHKYYRLY*
HKVCQCPSSNCGQSCLPWRSWRQSGGLNLLPSRA
RSRTESPQL*Q*GE*GQRPQSHHCNILPGG**L
RENPVQQHHCSQDRARQQLLGRGAKCAICTHQE
ELLHQ*QTRQAAEHSKPAKSLPEKQVLQAGGPRG
QPVHEETVQNIGFPKL*KQAQLNLLNIRHRRLK
NPALKFSPTPVFPLSLNHTCFILS*AKQAMLWE
VLTQR*LLGHRSRKHLI*PSARHRGFKACSHLLG
REGEEREKEGLEMNVYPQSQQKAMRAGETRGFE
HAPCQEASVDF*PLSRVVGCRAKLQNKIK*PAY
TMRYSKLPFCFLFTLAPSLVTDEEHPLYSV*AGS
KQFYLTSHILLMPTLL*LIIIKKKQGNSHSSPV
SYLFTSGATTVYPFLKKIREQKCLFVLQSK*KK
S*C*KNKSQVIYYIQWAFKSSRASSGECN*IILY
FLIYFVSHLSWMNSFTEYVILNLKKKKKK

Frame 1

PTTGCFVQAVPLLQNRASPPRSSRQCASIQPHL
VCMSTAAERGEVAVLRRFRGSGKAT*LVFQVPG
SLCPNGICRCGDDHGMPEPWGTVYFLGIAQVFSF
LFSWWNLEGVMNQADAPRPLNWTIRKLCHAAFL
PSVRLLKAQKSWIERAFYKRECVHIIPSTKDPH
RCCCGRLIGQHVGLTPSISVLQNEKNESRLSRND
IQSEKWSISKHTQLSPTDAFGTIEFQGGGHSNK
AMYVRVSFDTKPDLLLHLMTKEWQLELPKLLIS
VHGGLQNFELQPKLKQVFGKGLIKAAMTTGAWIF
TGGVNTGVIRHVGDALKDHASKSRGKICTIGIA
PWGIVENQEDLIGRDVVRPYQTMSNPMSKLTVL
NSMHSHFILADNGTTGKYGAEVKLRRQLEKHISL
QKINTRIGQGVPVVALIVEGGPNVISIVLEYLR
DTPPVPVVVCDGSGRASDILAFGHKYSEEGGLI
NESLRDQLLVTIQKTFTYTRTQAQHLFIILMECM
KKKELITVFRMGSEGHQDIDLAILTALLKGANA
SAPDQLSLALAWNRVDIARSQIFIYGQQWPVGS
LEQAMLDALVLDRVDFVKLLIENGVSMHRFLTIS
RLEELYNTRHGPSNTLYHLVRDVKKGNLPPDYR
ISLIDIGLVIEYLMGGAYRCNYTRKRFRTLYHN
LFGPKRPKALKLLGMEDDIPLRRGRKTTKKREEE
VDIDLDDPEINHFPFPFHELMVWAVLMKRQKMA
LFFWQHGEEAMAKALVACKLCKAMAHEASENDM
VDDISQELNHNSRDFGQLAVELLDQSYKQDEQLA
MKLLTYELKNWSNATCLQLAVAAKHRDFIAHTC
SQMLLTDMWMGRLRMRKNSGLKVILGILLPPSI
LSLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPT
KEKEEEDMELTAMLGRNNGESSRKKDEEEVQSK
HRLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLM
LFNYIVLVKMERWPSTQEWIVISYIFTLGIEKMR
EILMSEPGKLLQKVKVWLQEYWNVTDLIAILLF
SVGMILRLQDQPFRSDGRVIYCVNIIYWYIRLL
DIFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVL
MSFGVARQAILFPNEEPSWKLAKNIFYMPYWMI
YGEVFADQIDPPCGQNETREDGKIIQLPPCKTG
AWIVPAIMACYLLVANILLVNLLIAVFNNTFFEV
KSISNQVWKFQRYQLIMTFHERPVLPPPLIIFS
HMTMIFQHLCCRWRKHESDPDERDYGLKLFITD
DELKKVHDFEEQCIEEYFREKDDRFNSSNDERIR
VTSERVENMSMRLEEVNEREHSMKASLQTVDIR
LAQLEDLIGRMATALERLTGLERAESNKIRSRT
SSDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAG
EETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEK
LESIFKERSLSLHRATSSHSVAKEPKAPAAPAN
TLAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDN
SVNILGLGEPSFSTPVPSTAPSSSAYATLAPTD
RPPSRSIDFEDITSMDTRSFSSDYTHLPECQNP
WDSEPPMYHTIERSKSSRYLATTPFLLEEAPIVK
SHSFMFSPSRSYYANFGVPVKTAEYTSITDCID
TRCVNAPQAIADRAAFPGGLGDKVEDLTCCHPE
REAELSHPSSDSEENEAKGRRATIAISSQEGDNS
ERTLSNNITVPKIERANSYSAEEPSAPYAHTRK
SFSISDKLDRQRNTASLRNPFQRSKSSKPEGRG
DSLSMRRLSRTSAFQSFESKHN*TFLISATEGSR
IQP*NSLQLQFFPFP*IIPALFLAEQNKQCFGR
C*LKGDFWATDQESI*SDPVPDTGDLRHVHTCW
AGRGKRGRRKG*R*MCIRSHSRKP*EQGKQGASS
TLHARRHLLISDHYQEL*DAGLNCKIK*NSQRT
Q*DILNFHSVFFSHWLHHW*LMKSILFIQYKPA
ASSST*RPTSFSCQHFCN*SL*RKNKVTVIVHLS
LIYSLLVPQLFILF*RK*GNRNAFLYCNRNERR
VDVKKTKVK*FIIYSGRSSLVEQAQENVIK*FY
IF*FILYLTCHG*IHSLNM*Y*T*KKKKK

Frame 2

RPQAVLCRLSLFFKIVHPLPEAAGSVPPFSHIW
YA*ARLQREGRWLF*EGSGAQARLLD*SSKFQE
ASALMEFAGVEMTMGCQSRGGPFIF*ALLRFSV
SCFPGGIWKGS*IRLMLLDP*TGPSGSCATQPFF
HLSDF*RLRNPG*KEHFIKENVSTSYPAPKTPI
GVAVGV**ASMLASPPVSPCFRMRKMKVASPEM
TSSLKSGPSANTLNSALRMLLGPLSSKEVAIPTK
PCMCEYLLIQNLISSYT**PRNGSWSFPSFSSL
SMGACRTLNSSQNSSKSLGKGSSKQQ*QLERGY
SLEGLTQVLFVMLAMP*RIMPLSLEERYAP*VLP
PGELWKTRRTSLEEMLSGHTRPCPIP*ASSLFS
TACIPTSFWLTTGPLENMEQR*NFEDNWKSIFH
SRR*TQESVKVFLWWHS*WKEDPM*SRLFWSTFE
TPLPCQWLSVMGVDGHRTSWPLGINTQKKAD**
MNL*GTSCW*LYRRLSHTLEPKLSICSSSSWSA
*RRRN*LRYFGWDQKDTRTLIWLS*QLYSKEPMP
RPQTN*A*L*PGTESTSLAARSLFTGNSGRWDL
WSKPCWMP*FWTEWIL*NYS*RME*ACTVFSPS
PD*RNCTIRDMGPQIHCTTWSGMSKRGTCPQTTE
SA*LTSAW*SST*WAGLIAATTRASASGPSTTT
SSAPRGPKP*NCWEWRMIFP*GEEERQPRNVKK
RWTLTWMILRSTTSPSLSMSSWCGLFS*SGRRWP
CSSGSTVRRPWPRPWWPASSAKPWLMRPLRTTW
LTTFPRS*ITIPETLASWLWSSWTSPTSRTNSW
P*NC*RMS*RTGATPRACSLPWLPNTATSSRTRA
ARCCSPTCGWAGSACARTQASR*FWEFYFLLQF
SAWSSRTKTTCPICLRPRKSTSKRRRQKNQRSP
QRKKRKRTWSSQQCWDETTGSPPGRRMKRKFRAS
TG*SPSAEKSMNSTMHPS*SSGSTHWRISDT*C
SSTISC**RWNAGRPPRNGS*SPIFSPWE*KR*
ERF*CQSQGSCYRK*RYGCRSTGMSRTSSPSFCF
LSE*SFVSKTSPSGVTGGSSTA*TSFTGISVS*
TSSA*TSIWARM***LEK***T*CTLSSLCWWF
**ALGSPGKPSFFPMRSHHGNWPRTSSTCPIG*F
MGKCLRTR*TLPVDRMRPERMVK*SSCLPARQE
LGSCRPSWPATS*WQTSCWSTSSLLSLTIHFLK
*NRYPTKSGSFRGISSS*LSMKGQFCPHH*SSSA
T*P*YSSTCAADGGNTRATRMKGTTA*NSS*PM
MSSRKYMTLKSNA*KNTSEKRMIGSTHLMMRGY
G*LQKGWRTCLCGWRKSTRESTP*RLHSRPWTSG
WRSWKTLSGAWPRPWSA*QVWSGPSPTKSARGP
RQTARTPPTLSVRAASTARKGTPSSSKRV*TLQ
VRRPCPQLLQP*CPVCEAILSIRSI*KTKVV*KS
WKVFLKKGP*AYTGLLVPTL*QKNPKLLQPLPT
PWPLFLIPEDHHRV*TSMSLLWMSSTVI*TLWT
IP*TSLGWASQAFQLQYLPQPLQVVPMQHLHPQT
DLQAGALILRTSPPWTLDLFLQTTPTSQNAKTP
GTQSLRCTTPLSVPKVAAT*PPHPFF*KRLPL*
NLIALCFPPQGAIMPTLGCL*KQQNTQVLQTVLT
QGVSMPLKQLRTELPSLEVLETKWRT*LAAIQS
EKQN*VTPALTVRRMRPKAAEPPLQYPPRRVIT
QREPCPTTSLFPR*SAPTATRQRSQVRHMHTPGR
ASPSVTNSTGSGTQQACEIPSREASPPSRRAEG
TACP*GDCPEHRLSKALKASTTKPS*YPPQKAQ
ESSPKILSNSSFSPFLESYLLYS*LSKTSNALGG
VNSKVTSGPQIKKAFDLTQCQTQGI*GMFTLAG
QGGGREGEGRVRDECVSAVTAESHESRGNKGLR
ARSMPGGIC*FLTIIKSCRMQG*IAK*NKIASVH
NEIF*TSILFSFHIGSITGD**RASSLFSISRQ
QAVLPNVPHPSHANTSVIDHYKEKTR*QS*FTC
LLSIHFWCHNCLSFFEENKGTEMPFCIAIEMKEE
LMLKKQKSSDLLYTVGVQV*SSKLRRM*LNNFI
FFNLFCISPVMDEFIH*ICNIELKKKKKK

Sequence NM_020952

AGCTGCAGCAAAATGAAAGCAACAGGAGCTGCTCCGGGGACTGCTTTTGCCAGTACCCAGAATCAGTGCTCAGGCTCAGAAATCCTGGATAGAAAGAGCA
TTTTATAAAAGAGAATGTGTCCACATCATACCCAGCACCAAAGACCCCCATAGGTGTTGCTGTGGGCGTCTGATAGGCCAGCATGTTGGCCTCACCCCCA
GTATCTCCGTGCTTCAGAATGAGAAAAATGAAAGTCGCCTCTCCCGAAATGACATCCAGTCTGAAAAGTGGTCCATCAGCAAACACACTCAACTCAGCCC
TACGGATGCTTTTGGGACCATTGAGTTCCAAGGAGGTGGCCATTCCAACAAAGCCATGTATGTGCGAGTATCTTTTGATACAAAACCTGATCTCCTCTTA
CACCTGATGACCAAGGAATGGCAGTTGGAGCTTCCCAAGCTTCTCATCTCTGTCCATGGGGGCCTGCAGAACTTTGAACTCCAGCCAAAACTCAAGCAAG
TCTTTGGGAAAGGGCTCATCAAAGCAGCAATGACAACTGGAGCGTGGATATTCACTGGAGGGGTTAACACAGGTGTTATTCGTCATGTTGGCGATGCCTT
GAAGGATCATGCCTCTAAGTCTCGAGGAAAGATATGCACCATAGGTATTGCCCCCTGGGGAATTGTGGAAAACCAGGAGGACCTCATTGGAAGAGATGTT
GTCCGGCCATACCAGACCATGTCCAATCCCATGAGCAAGCTCACTGTTCTCAACAGCATGCATTCCCACTTCATTCTGGCTGACAACGGGACCACTGGAA
AATATGGAGCAGAGGTGAAACTTCGAAGACAACTGGAAAAGCATATTTCACTCCAGAAGATAAACACAAGAATCGGTCAAGGTGTTCCTGTGGTGGCACT
CATAGTGGAAGGAGGACCCAATGTGATCTCGATTGTTTTGGAGTACCTTCGAGACACCCCTCCCGTGCCAGTGGTTGTCTGTGATGGGAGTGGACGGGCA
TCGGACATCCTGGCCTTTGGGCATAAATACTCAGAAGAAGGCGGACTGATAAATGAATCTTTGAGGGACCAGCTGTTGGTGACTATACAGAAGACTTTCA
CATACACTCGAACCCAAGCTCAGCATCTGTTCATCATCCTCATGGAGTGCATGAAGAAGAAGGAATTGATTACGGTATTTCGGATGGGATCAGAAGGACA
CCAGGACATTGATTTGGCTATCCTGACAGCTTTACTCAAAGGAGCCAATGCCTCGGCCCCAGACCAACTGAGCTTAGCTTTAGCCTGGAACAGAGTCGAC
ATCGCTCGCAGCCAGATCTTTATTTACGGGCAACAGTGGCCGGTGGGATCTCTGGAGCAAGCCATGTTGGATGCCTTAGTTCTGGACAGAGTGGATTTTG
TGAAATTACTCATAGAGAATGGAGTAAGCATGCACCGTTTTCTCACCATCTCCAGACTAGAGGAATTGTACAATACGAGACATGGGCCCTCAAATACATT
GTACCACTTGGTCAGGGATGTCAAAAAGGGGAACCTGCCCCCAGACTACAGAATCAGCCTGATTGACATCGGCCTGGTGATCGAGTACCTGATGGGCGGG
GCTTATCGCTGCAACTACACGCGCAAGCGCTTCCGGACCCTCTACCACAACCTCTTCGGCCCCAAGAGGCCCAAAGCCTTGAAACTGCTGGGAATGGAGG
ATGATATTCCCTTGAGGCGAGGAAGAAAGACAACCAAGAAACGTGAAGAAGAGGTGGACATTGACTTGGATGATCCTGAGATCAACCACTTCCCCTTCCC
TTTCCATGAGCTCATGGTGTGGGCTGTTCTCATGAAGCGGCAGAAGATGGCCCTGTTCTTCTGGCAGCACGGTGAGGAGGCCATGGCCAAGGCCCTGGTG
GCCTGCAAGCTCTGCAAAGCCATGGCTCATGAGGCCTCTGAGAACGACATGGTTGACGACATTTCCCAGGAGCTGAATCACAATTCCAGAGACTTTGGCC
AGCTGGCTGTGGAGCTCCTGGACCAGTCCTACAAGCAGGACGAACAGCTGGCCATGAAACTGCTGACGTATGAGCTGAAGAACTGGAGCAACGCCACGTG
CCTGCAGCTTGCCGTGGCTGCCAAACACCGCGACTTCATCGCGCACACGTGCAGCCAGATGCTGCTCACCGACATGTGGATGGGCCGGCTCCGCATGCGC
AAGAACTCAGGCCTCAAGGTAATTCTGGGAATTCTACTTCCTCCTTCAATTCTCAGCTTGGAGTTCAAGAACAAAGACGACATGCCCTATATGTCTCAGG
CCCAGGAAATCCACCTCCAAGAGAAGGAGGCAGAAGAACCAGAGAAGCCCACAAAGGAAAAAGAGGAAGAGGACATGGAGCTCACAGCAATGTTGGGACG
AAACAACGGGGAGTCCTCCAGGAAGAAGGATGAAGAGGAAGTTCAGAGCAAGCACCGGTTAATCCCCCTCGGCAGAAAAATCTATGAATTCTACAATGCA
CCCATCGTGAAGTTCTGGTTCTACACACTGGCGTATATCGGATACCTGATGCTCTTCAACTATATCGTGTTAGTGAAGATGGAACGCTGGCCGTCCACCC
AGGAATGGATCGTAATCTCCTATATTTTCACCCTGGGAATAGAAAAGATGAGAGAGATTCTGATGTCAGAGCCAGGGAAGTTGCTACAGAAAGTGAAGGT
ATGGCTGCAGGAGTACTGGAATGTCACGGACCTCATCGCCATCCTTCTGTTTTCTGTCGGAATGATCCTTCGTCTCCAAGACCAGCCCTTCAGGAGTGAC
GGGAGGGTCATCTACTGCGTGAACATCATTTACTGGTATATCCGTCTCCTAGACATCTTCGGCGTGAACAAGTATTTGGGCCCGTATGTAATGATGATTG
GAAAAATGATGATAGACATGATGTACTTTGTCATCATTATGCTGGTGGTTCTGATGAGCTTTGGGGTCGCCAGGCAAGCCATCCTTTTTCCCAATGAGGA
GCCATCATGGAAACTGGCCAAGAACATCTTCTACATGCCCTATTGGATGATTTATGGGGAAGTGTTTGCGGACCAGATAGACCCTCCCTGTGGACAGAAT
GAGACCCGAGAGGATGGTAAAATAATCCAGCTGCCTCCCTGCAAGACAGGAGCTTGGATCGTGCCGGCCATCATGGCCTGCTACCTCTTAGTGGCAAACA
TCTTGCTGGTCAACCTCCTCATTGCTGTCTTTAACAATACATTTTTTGAAGTAAAATCGATATCCAACCAAGTCTGGAAGTTTCAGAGGTATCAGCTCAT
CATGACTTTCCATGAAAGGCCAGTTCTGCCCCCACCACTGATCATCTTCAGCCACATGACCATGATATTCCAGCACCTGTGCTGCCGATGGAGGAAACAC
GAGAGCGACCCGGATGAAAGGGACTACGGCCTGAAACTCTTCATAACCGATGATGAGCTCAAGAAAGTACATGACTTTGAAGAGCAATGCATAGAAGAAT
ACTTCAGAGAAAAGGATGATCGGTTCAACTCATCTAATGATGAGAGGATACGGGTGACTTCAGAAAGGGTGGAGAACATGTCTATGCGGCTGGAGGAAGT
CAACGAGAGAGAGCACTCCATGAAGGCTTCACTCCAGACCGTGGACATCCGGCTGGCGCAGCTGGAAGACCTTATCGGGCGCATGGCCACGGCCCTGGAG
CGCCTGACAGGTCTGGAGCGGGCCGAGTCCAACAAAATCCGCTCGAGGACCTCGTCAGACTGCACGGACGCCGCCTACATTGTCCGTCAGAGCAGCTTCA
ACAGCCAGGAAGGGAACACCTTCAAGCTCCAAGAGAGTATAGACCCTGCAGGTGAGGAGACCATGTCCCCAACTTCTCCAACCTTAATGCCCCGTATGCG
AAGCCATTCTTTCTATTCGGTCAATATGAAAGACAAAGGTGGTATAGAAAAGTTGGAAAGTATTTTTAAAGAAAGGTCCCTGAGCCTACACCGGGCTACT
AGTTCCCACTCTGTAGCAAAAGAACCCAAAGCTCCTGCAGCCCCTGCCAACACCTTGGCCATTGTTCCTGATTCCAGAAGACCATCATCGTGTATAGACA
TCTATGTCTCTGCTATGGATGAGCTCCACTGTGATATAGACCCTCTGGACAATTCCGTGAACATCCTTGGGCTGGGCGAGCCAAGCTTTTCAACTCCAGT
ACCTTCCACAGCCCCTTCAAGTAGTGCCTATGCAACACTTGCACCCACAGACAGACCTCCAAGCCGGAGCATTGATTTTGAGGACATCACCTCCATGGAC
ACTAGATCTTTTTCTTCAGACTACACCCACCTCCCAGAATGCCAAAACCCCTGGGACTCAGAGCCTCCGATGTACCACACCATTGAGCGTTCCAAAAGTA
GCCGCTACCTAGCCACCACACCCTTTCTTCTAGAAGAGGCTCCCATTGTGAAATCTCATAGCTTTATGTTTTCCCCCTCAAGGAGCTATTATGCCAACTT
TGGGGTGCCTGTAAAAACAGCAGAATACACAAGTATTACAGACTGTATTGACACAAGGTGTGTCAATGCCCCTCAAGCAATTGCGGACAGAGCTGCCTTC
CCTGGAGGTCTTGGAGACAAAGTGGAGGACTTAACTTGCTGCCATCCAGAGCGAGAAGCAGAACTGAGTCACCCCAGCTCTGACAGTGAGGAGAATGAGG
CCAAAGGCCGCAGAGCCACCATTGCAATATCCTCCCAGGAGGGTGATAACTCAGAGAGAACCCTGTCCAACAACATCACTGTTCCCAAGATAGAGCGCGC
CAACAGCTACTCGGCAGAGGAGCCAAGTGCGCCATATGCACACACCAGGAAGAGCTTCTCCATCAGTGACAAACTCGACAGGCAGCGGAACACAGCAAGC
CTGCGAAATCCCTTCCAGAGAAGCAAGTCCTCCAAGCCGGAGGGCCGAGGGGACAGCCTGTCCATGAGGAGACTGTCCAGAACATCGGCTTTCCAAAGCT
TTGAAAGCAAGCACAACTAAACCTTCTTAATATCCGCCACAGAAGGCTCAAGAATCCAGCCCTAAAATTCTCTCCAACTCCAGTTTTTCCCCTTTCCTTG
AATCATACCTGCTTTATTCTTAGCTGAGCAAAACAAGCAATGCTTTGGGAGGTGTTAACTCAAAGGTGACTTCTGGGCCACAGATCAAGAAAGCATTTGA
TCTGACCCAGTGCCAGACACAGGGGATTTAAGGCATGTTCACACTTGCTGGGCAGGGAGGGGGAAGAGAGGGAGAAGGAAGGGTTAGAGATGAATGTGTA
TCCGCAGTCACAGCAGAAAGCCATGAGAGCAGGGGAAACAAGGGGCTTCGAGCACGCTCCATGCCAGGAGGCATCTGTTGATTTCTGACCATTATCAAGA
GTTGTAGGATGCAGGGCTAAATTGCAAAATAAAATAAAATAGCCAGCGTACACAATGAGATATTCTAAACTTCCATTCTGTTTTCTTTTCACATTGGCTC
CATCACTGGTGACTGATGAAGAGCATCCTCTTTATTCAGTATAAGCCGGCAGCAAGCAGTTCTACCTAACGTCCCACATCCTTCTCATGCCAACACTTCT
GTAATTGATCATTATAAAGAAAAAACAAGGTAACAGTCATAGTTCACCTGTCTCTTATCTATTCACTTCTGGTGCCACAACTGTTTATCCTTTTTTGAAG
AAAATAAGGGAACAGAAATGCCTTTTTGTATTGCAATCGAAATGAAAGAAGAGTTGATGTTAAAAAAACAAAAGTCAAGTGATTTATTATATACAGTGGG
CGTTCAAGTCTAGTCGAGCAAGCTCAGGAGAATGTAATTAAATAATTTTATATTTTTTAATTTATTTTGTATCTCACCTGTCATGGATGAATTCATTCAC
TGAATATGTAATATTGAACTTAAAAAAAAAAAAAAAAAAA
  • refseq_TRPM3.F6 (forward primer)
  • refseq_TRPM3.R6 (reverse primer)
  • Single exon skipping

Frame 0

SCSKMKATGAAPGTAFASTQNQCSGSEILDRKS
IL*KRMCPHHTQHQRPP*VLLWASDRPACWPHPQ
YLRASE*EK*KSPLPK*HPV*KVVHQQTHSTQP
YGCFWDH*VPRRWPFQQSHVCASIF*YKT*SPL
TPDDQGMAVGASQASHLCPWGPAEL*TPAKTQAS
LWERAHQSSNDNWSVDIHWRG*HRCYSSCWRCL
EGSCL*VSRKDMHHRYCPLGNCGKPGGPHWKRC
CPAIPDHVQSHEQAHCSQQHAFPLHSG*QRDHWK
IWSRGETSKTTGKAYFTPEDKHKNRSRCSCGGT
HSGRRTQCDLDCFGVPSRHPSRASGCL*WEWTG
IGHPGLWA*ILRRRRTDK*IFEGPAVGDYTEDFH
IHSNPSSASVHHPHGVHEEEGIDYGISDGIRRT
PGH*FGYPDSFTQRSQCLGPRPTELSFSLEQSR
HRSQPDLYLRATVAGGISGASHVGCLSSGQSGFC
EITHREWSKHAPFSHHLQTRGIVQYETWALKYI
VPLGQGCQKGEPAPRLQNQPD*HRPGDRVPDGR
GLSLQLHAQALPDPLPQPLRPQEAQSLETAGNGG
*YSLEARKKDNQET*RRGGH*LG*S*DQPLPLP
FP*AHGVGCSHEAAEDGPVLLAAR*GGHGQGPG
GLQALQSHGS*GL*ERHG*RHFPGAESQFQRLWP
AGCGAPGPVLQAGRTAGHETADV*AEELEQRHV
PAACRGCQTPRLHRAHVQPDAAHRHVDGPAPHA
QELRPQGNSGNSTSSFNSQLGVQEQRRHALYVSG
PGNPPPREGGRRTREAHKGKRGRGHGAHSNVGT
KQRGVLQEEG*RGSSEQAPVNPPRQKNL*ILQC
THREVLVLHTGVYRIPDALQLYRVSEDGTLAVHP
GMDRNLLYFHPGNRKDERDSDVRAREVATESEG
MAAGVLECHGPHRHPSVFCRNDPSSPRPALQE*
REGHLLREHHLLVYPSPRHLRREQVFGPVCNDDW
KNDDRHDVLCHHYAGGSDELWGRQASHPFSQ*G
AIMETGQEHLLHALLDDLWGSVCGPDRPSLWTE
*DPRGW*NNPAASLQDRSLDRAGHHGLLPLSGKH
LAGQPPHCCL*QYIF*SKIDIQPSLEVSEVSAH
HDFP*KASSAPTTDHLQPHDHDIPAPVLPMEET
RERPG*KGLRPETLHNR**AQEST*L*RAMHRRI
LQRKG*SVQLI***EDTGDFRKGGEHVYAAGGS
QRERALHEGFTPDRGHPAGAAGRPYRAHGHGPG
APDRSGAGRVQQNPLEDLVRLHGRRLHCPSEQLQ
QPGREHLQAPREYRPCR*GDHVPNFSNLNAPYA
KPFFLFGQYERQRWYRKVGKYF*RKVPEPTPGY
*FPLCSKRTQSSCSPCQHLGHCS*FQKTIIVYRH
LCLCYG*APL*YRPSGQFREHPWAGRAKLFNSS
TFHSPFK*CLCNTCTHRQTSKPEH*F*GHHLHG
H*IFFFRLHPPPRMPKPLGLRASDVPHH*AFQK*
PLPSHHTLSSRRGSHCEIS*LYVFPLKELLCQL
WGACKNSRIHKYYRLY*HKVCQCPSSNCGQSCL
PWRSWRQSGGLNLLPSRARSRTESPQL*Q*GE*G
QRPQSHHCNILPGG**LRENPVQQHHCSQDRAR
QQLLGRGAKCAICTHQEELLHQ*QTRQAAEHSK
PAKSLPEKQVLQAGGPRGQPVHEETVQNIGFPKL
*KQAQLNLLNIRHRRLKNPALKFSPTPVFPLSL
NHTCFILS*AKQAMLWEVLTQR*LLGHRSRKHL
I*PSARHRGFKACSHLLGREGEEREKEGLEMNVY
PQSQQKAMRAGETRGFEHAPCQEASVDF*PLSR
VVGCRAKLQNKIK*PAYTMRYSKLPFCFLFTLA
PSLVTDEEHPLYSV*AGSKQFYLTSHILLMPTLL
*LIIIKKKQGNSHSSPVSYLFTSGATTVYPFLK
KIREQKCLFVLQSK*KKS*C*KNKSQVIYYIQW
AFKSSRASSGECN*IILYFLIYFVSHLSWMNSFT
EYVILNLKKKKKK

Frame 1

AAAK*KQQELLRGLLLPVPRISAQAQKSWIERA
FYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTP
SISVLQNEKNESRLSRNDIQSEKWSISKHTQLSP
TDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLL
HLMTKEWQLELPKLLISVHGGLQNFELQPKLKQ
VFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDAL
KDHASKSRGKICTIGIAPWGIVENQEDLIGRDV
VRPYQTMSNPMSKLTVLNSMHSHFILADNGTTG
KYGAEVKLRRQLEKHISLQKINTRIGQGVPVVAL
IVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTF
TYTRTQAQHLFIILMECMKKKELITVFRMGSEGH
QDIDLAILTALLKGANASAPDQLSLALAWNRVD
IARSQIFIYGQQWPVGSLEQAMLDALVLDRVDF
VKLLIENGVSMHRFLTISRLEELYNTRHGPSNTL
YHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGG
AYRCNYTRKRFRTLYHNLFGPKRPKALKLLGME
DDIPLRRGRKTTKKREEEVDIDLDDPEINHFPFP
FHELMVWAVLMKRQKMALFFWQHGEEAMAKALV
ACKLCKAMAHEASENDMVDDISQELNHNSRDFG
QLAVELLDQSYKQDEQLAMKLLTYELKNWSNATC
LQLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMR
KNSGLKVILGILLPPSILSLEFKNKDDMPYMSQ
AQEIHLQEKEAEEPEKPTKEKEEEDMELTAMLGR
NNGESSRKKDEEEVQSKHRLIPLGRKIYEFYNA
PIVKFWFYTLAYIGYLMLFNYIVLVKMERWPST
QEWIVISYIFTLGIEKMREILMSEPGKLLQKVKV
WLQEYWNVTDLIAILLFSVGMILRLQDQPFRSD
GRVIYCVNIIYWYIRLLDIFGVNKYLGPYVMMI
GKMMIDMMYFVIIMLVVLMSFGVARQAILFPNEE
PSWKLAKNIFYMPYWMIYGEVFADQIDPPCGQN
ETREDGKIIQLPPCKTGAWIVPAIMACYLLVAN
ILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLI
MTFHERPVLPPPLIIFSHMTMIFQHLCCRWRKH
ESDPDERDYGLKLFITDDELKKVHDFEEQCIEE
YFREKDDRFNSSNDERIRVTSERVENMSMRLEEV
NEREHSMKASLQTVDIRLAQLEDLIGRMATALE
RLTGLERAESNKIRSRTSSDCTDAAYIVRQSSF
NSQEGNTFKLQESIDPAGEETMSPTSPTLMPRMR
SHSFYSVNMKDKGGIEKLESIFKERSLSLHRAT
SSHSVAKEPKAPAAPANTLAIVPDSRRPSSCID
IYVSAMDELHCDIDPLDNSVNILGLGEPSFSTPV
PSTAPSSSAYATLAPTDRPPSRSIDFEDITSMD
TRSFSSDYTHLPECQNPWDSEPPMYHTIERSKS
SRYLATTPFLLEEAPIVKSHSFMFSPSRSYYANF
GVPVKTAEYTSITDCIDTRCVNAPQAIADRAAF
PGGLGDKVEDLTCCHPEREAELSHPSSDSEENE
AKGRRATIAISSQEGDNSERTLSNNITVPKIERA
NSYSAEEPSAPYAHTRKSFSISDKLDRQRNTAS
LRNPFQRSKSSKPEGRGDSLSMRRLSRTSAFQS
FESKHN*TFLISATEGSRIQP*NSLQLQFFPFP*
IIPALFLAEQNKQCFGRC*LKGDFWATDQESI*
SDPVPDTGDLRHVHTCWAGRGKRGRRKG*R*MC
IRSHSRKP*EQGKQGASSTLHARRHLLISDHYQE
L*DAGLNCKIK*NSQRTQ*DILNFHSVFFSHWL
HHW*LMKSILFIQYKPAASSST*RPTSFSCQHF
CN*SL*RKNKVTVIVHLSLIYSLLVPQLFILF*R
K*GNRNAFLYCNRNERRVDVKKTKVK*FIIYSG
RSSLVEQAQENVIK*FYIF*FILYLTCHG*IHS
LNM*Y*T*KKKKK

Frame 2

LQQNESNRSCSGDCFCQYPESVLRLRNPG*KEH
FIKENVSTSYPAPKTPIGVAVGV**ASMLASPP
VSPCFRMRKMKVASPEMTSSLKSGPSANTLNSA
LRMLLGPLSSKEVAIPTKPCMCEYLLIQNLISSY
T**PRNGSWSFPSFSSLSMGACRTLNSSQNSSK
SLGKGSSKQQ*QLERGYSLEGLTQVLFVMLAMP
*RIMPLSLEERYAP*VLPPGELWKTRRTSLEEML
SGHTRPCPIP*ASSLFSTACIPTSFWLTTGPLE
NMEQR*NFEDNWKSIFHSRR*TQESVKVFLWWH
S*WKEDPM*SRLFWSTFETPLPCQWLSVMGVDGH
RTSWPLGINTQKKAD**MNL*GTSCW*LYRRLS
HTLEPKLSICSSSSWSA*RRRN*LRYFGWDQKD
TRTLIWLS*QLYSKEPMPRPQTN*A*L*PGTEST
SLAARSLFTGNSGRWDLWSKPCWMP*FWTEWIL
*NYS*RME*ACTVFSPSPD*RNCTIRDMGPQIH
CTTWSGMSKRGTCPQTTESA*LTSAW*SST*WAG
LIAATTRASASGPSTTTSSAPRGPKP*NCWEWR
MIFP*GEEERQPRNVKKRWTLTWMILRSTTSPS
LSMSSWCGLFS*SGRRWPCSSGSTVRRPWPRPWW
PASSAKPWLMRPLRTTWLTTFPRS*ITIPETLA
SWLWSSWTSPTSRTNSWP*NC*RMS*RTGATPR
ACSLPWLPNTATSSRTRAARCCSPTCGWAGSACA
RTQASR*FWEFYFLLQFSAWSSRTKTTCPICLR
PRKSTSKRRRQKNQRSPQRKKRKRTWSSQQCWD
ETTGSPPGRRMKRKFRASTG*SPSAEKSMNSTMH
PS*SSGSTHWRISDT*CSSTISC**RWNAGRPP
RNGS*SPIFSPWE*KR*ERF*CQSQGSCYRK*R
YGCRSTGMSRTSSPSFCFLSE*SFVSKTSPSGVT
GGSSTA*TSFTGISVS*TSSA*TSIWARM***L
EK***T*CTLSSLCWWF**ALGSPGKPSFFPMR
SHHGNWPRTSSTCPIG*FMGKCLRTR*TLPVDRM
RPERMVK*SSCLPARQELGSCRPSWPATS*WQT
SCWSTSSLLSLTIHFLK*NRYPTKSGSFRGISS
S*LSMKGQFCPHH*SSSAT*P*YSSTCAADGGNT
RATRMKGTTA*NSS*PMMSSRKYMTLKSNA*KN
TSEKRMIGSTHLMMRGYG*LQKGWRTCLCGWRK
STRESTP*RLHSRPWTSGWRSWKTLSGAWPRPWS
A*QVWSGPSPTKSARGPRQTARTPPTLSVRAAS
TARKGTPSSSKRV*TLQVRRPCPQLLQP*CPVC
EAILSIRSI*KTKVV*KSWKVFLKKGP*AYTGLL
VPTL*QKNPKLLQPLPTPWPLFLIPEDHHRV*T
SMSLLWMSSTVI*TLWTIP*TSLGWASQAFQLQ
YLPQPLQVVPMQHLHPQTDLQAGALILRTSPPWT
LDLFLQTTPTSQNAKTPGTQSLRCTTPLSVPKV
AAT*PPHPFF*KRLPL*NLIALCFPPQGAIMPT
LGCL*KQQNTQVLQTVLTQGVSMPLKQLRTELPS
LEVLETKWRT*LAAIQSEKQN*VTPALTVRRMR
PKAAEPPLQYPPRRVITQREPCPTTSLFPR*SA
PTATRQRSQVRHMHTPGRASPSVTNSTGSGTQQA
CEIPSREASPPSRRAEGTACP*GDCPEHRLSKA
LKASTTKPS*YPPQKAQESSPKILSNSSFSPFL
ESYLLYS*LSKTSNALGGVNSKVTSGPQIKKAFD
LTQCQTQGI*GMFTLAGQGGGREGEGRVRDECV
SAVTAESHESRGNKGLRARSMPGGIC*FLTIIK
SCRMQG*IAK*NKIASVHNEIF*TSILFSFHIGS
ITGD**RASSLFSISRQQAVLPNVPHPSHANTS
VIDHYKEKTR*QS*FTCLLSIHFWCHNCLSFFE
ENKGTEMPFCIAIEMKEELMLKKQKSSDLLYTVG
VQV*SSKLRRM*LNNFIFFNLFCISPVMDEFIH
*ICNIELKKKKKK

Sequence NM_206948

AGCTGCAGCAAAATGAAAGCAACAGGAGCTGCTCCGGGGACTGCTTTTGCCAGTACCCAGAATCAGTGCTCAGGCTCAGAAATCCTGGATAGAAAGAGCA
TTTTATAAAAGAGAATGTGTCCACATCATACCCAGCACCAAAGACCCCCATAGGTGTTGCTGTGGGCGTCTGATAGGCCAGCATGTTGGCCTCACCCCCA
GTATCTCCGTGCTTCAGAATGAGAAAAATGAAAGTCGCCTCTCCCGAAATGACATCCAGTCTGAAAAGTGGTCCATCAGCAAACACACTCAACTCAGCCC
TACGGATGCTTTTGGGACCATTGAGTTCCAAGGAGGTGGCCATTCCAACAAAGCCATGTATGTGCGAGTATCTTTTGATACAAAACCTGATCTCCTCTTA
CACCTGATGACCAAGGAATGGCAGTTGGAGCTTCCCAAGCTTCTCATCTCTGTCCATGGGGGCCTGCAGAACTTTGAACTCCAGCCAAAACTCAAGCAAG
TCTTTGGGAAAGGGCTCATCAAAGCAGCAATGACAACTGGAGCGTGGATATTCACTGGAGGGGTTAACACAGGTGTTATTCGTCATGTTGGCGATGCCTT
GAAGGATCATGCCTCTAAGTCTCGAGGAAAGATATGCACCATAGGTATTGCCCCCTGGGGAATTGTGGAAAACCAGGAGGACCTCATTGGAAGAGATGTT
GTCCGGCCATACCAGACCATGTCCAATCCCATGAGCAAGCTCACTGTTCTCAACAGCATGCATTCCCACTTCATTCTGGCTGACAACGGGACCACTGGAA
AATATGGAGCAGAGGTGAAACTTCGAAGACAACTGGAAAAGCATATTTCACTCCAGAAGATAAACACAAGAATCGGTCAAGGTGTTCCTGTGGTGGCACT
CATAGTGGAAGGAGGACCCAATGTGATCTCGATTGTTTTGGAGTACCTTCGAGACACCCCTCCCGTGCCAGTGGTTGTCTGTGATGGGAGTGGACGGGCA
TCGGACATCCTGGCCTTTGGGCATAAATACTCAGAAGAAGGCGGGTAGGTAACTTTCCAGGCCCCATGGAAGAACCCTAAAGCCTGTTTGGAAACGAGGG
TATGAGTGGATTATGTTTTCAGTAGCTCAACCAAGACCTCAAATCAAAACAAGCTATGAACAAATTGTCTAAAAAATGTCTGTCATGGGAGGGCTGTGGT
GAAGAACAGAGAAACATATTCTAAATGTCCTGTGAAGTGGGAAATTCTATGAAAGCTACACGGATAATAAAAAGGGTGAGGAAAAGA
  • refseq_TRPM3.F6 (forward primer)
  • refseq_TRPM3.R6 (reverse primer)
  • Single exon skipping

Frame 0

SCSKMKATGAAPGTAFASTQNQCSGSEILDRKS
IL*KRMCPHHTQHQRPP*VLLWASDRPACWPHPQ
YLRASE*EK*KSPLPK*HPV*KVVHQQTHSTQP
YGCFWDH*VPRRWPFQQSHVCASIF*YKT*SPL
TPDDQGMAVGASQASHLCPWGPAEL*TPAKTQAS
LWERAHQSSNDNWSVDIHWRG*HRCYSSCWRCL
EGSCL*VSRKDMHHRYCPLGNCGKPGGPHWKRC
CPAIPDHVQSHEQAHCSQQHAFPLHSG*QRDHWK
IWSRGETSKTTGKAYFTPEDKHKNRSRCSCGGT
HSGRRTQCDLDCFGVPSRHPSRASGCL*WEWTG
IGHPGLWA*ILRRRRVGNFPGPMEEP*SLFGNEG
MSGLCFQ*LNQDLKSKQAMNKLSKKCLSWEGCG
EEQRNIF*MSCEVGNSMKATRIIKRVRKR

Frame 1

AAAK*KQQELLRGLLLPVPRISAQAQKSWIERA
FYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTP
SISVLQNEKNESRLSRNDIQSEKWSISKHTQLSP
TDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLL
HLMTKEWQLELPKLLISVHGGLQNFELQPKLKQ
VFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDAL
KDHASKSRGKICTIGIAPWGIVENQEDLIGRDV
VRPYQTMSNPMSKLTVLNSMHSHFILADNGTTG
KYGAEVKLRRQLEKHISLQKINTRIGQGVPVVAL
IVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
SDILAFGHKYSEEGG*VTFQAPWKNPKACLETR
V*VDYVFSSSTKTSNQNKL*TNCLKNVCHGRAVV
KNRETYSKCPVKWEIL*KLHG**KG*GK

Frame 2

LQQNESNRSCSGDCFCQYPESVLRLRNPG*KEH
FIKENVSTSYPAPKTPIGVAVGV**ASMLASPP
VSPCFRMRKMKVASPEMTSSLKSGPSANTLNSA
LRMLLGPLSSKEVAIPTKPCMCEYLLIQNLISSY
T**PRNGSWSFPSFSSLSMGACRTLNSSQNSSK
SLGKGSSKQQ*QLERGYSLEGLTQVLFVMLAMP
*RIMPLSLEERYAP*VLPPGELWKTRRTSLEEML
SGHTRPCPIP*ASSLFSTACIPTSFWLTTGPLE
NMEQR*NFEDNWKSIFHSRR*TQESVKVFLWWH
S*WKEDPM*SRLFWSTFETPLPCQWLSVMGVDGH
RTSWPLGINTQKKAGR*LSRPHGRTLKPVWKRG
YEWIMFSVAQPRPQIKTSYEQIV*KMSVMGGLW
*RTEKHILNVL*SGKFYESYTDNKKGEEK

Sequence NM_206944

AGCTGCAGCAAAATGAAAGCAACAGGAGCTGCTCCGGGGACTGCTTTTGCCAGTACCCAGAATCAGTGCTCAGGCTCAGAAATCCTGGATAGAAAGAGCA
TTTTATAAAAGAGAATGTGTCCACATCATACCCAGCACCAAAGACCCCCATAGGTGTTGCTGTGGGCGTCTGATAGGCCAGCATGTTGGCCTCACCCCCA
GTATCTCCGTGCTTCAGAATGAGAAAAATGAAAGTCGCCTCTCCCGAAATGACATCCAGTCTGAAAAGTGGTCCATCAGCAAACACACTCAACTCAGCCC
TACGGATGCTTTTGGGACCATTGAGTTCCAAGGAGGTGGCCATTCCAACAAAGCCATGTATGTGCGAGTATCTTTTGATACAAAACCTGATCTCCTCTTA
CACCTGATGACCAAGGAATGGCAGTTGGAGCTTCCCAAGCTTCTCATCTCTGTCCATGGGGGCCTGCAGAACTTTGAACTCCAGCCAAAACTCAAGCAAG
TCTTTGGGAAAGGGCTCATCAAAGCAGCAATGACAACTGGAGCGTGGATATTCACTGGAGGGGTTAACACAGGTGTTATTCGTCATGTTGGCGATGCCTT
GAAGGATCATGCCTCTAAGTCTCGAGGAAAGATATGCACCATAGGTATTGCCCCCTGGGGAATTGTGGAAAACCAGGAGGACCTCATTGGAAGAGATGTT
GTCCGGCCATACCAGACCATGTCCAATCCCATGAGCAAGCTCACTGTTCTCAACAGCATGCATTCCCACTTCATTCTGGCTGACAACGGGACCACTGGAA
AATATGGAGCAGAGGTGAAACTTCGAAGACAACTGGAAAAGCATATTTCACTCCAGAAGATAAACACAAGAATCGGTCAAGGTGTTCCTGTGGTGGCACT
CATAGTGGAAGGAGGACCCAATGTGATCTCGATTGTTTTGGAGTACCTTCGAGACACCCCTCCCGTGCCAGTGGTTGTCTGTGATGGGAGTGGACGGGCA
TCGGACATCCTGGCCTTTGGGCATAAATACTCAGAAGAAGGCGGACTGATAAATGAATCTTTGAGGGACCAGCTGTTGGTGACTATACAGAAGACTTTCA
CATACACTCGAACCCAAGCTCAGCATCTGTTCATCATCCTCATGGAGTGCATGAAGAAGAAGGAATTGATTACGGTATTTCGGATGGGATCAGAAGGACA
CCAGGACATTGATTTGGCTATCCTGACAGCTTTACTCAAAGGAGCCAATGCCTCGGCCCCAGACCAACTGAGCTTAGCTTTAGCCTGGAACAGAGTCGAC
ATCGCTCGCAGCCAGATCTTTATTTACGGGCAACAGTGGCCGGTGGGATCTCTGGAGCAAGCCATGTTGGATGCCTTAGTTCTGGACAGAGTGGATTTTG
TGAAATTACTCATAGAGAATGGAGTAAGCATGCACCGTTTTCTCACCATCTCCAGACTAGAGGAATTGTACAATACGAGACATGGGCCCTCAAATACATT
GTACCACTTGGTCAGGGATGTCAAAAAGGGGAACCTGCCCCCAGACTACAGAATCAGCCTGATTGACATCGGCCTGGTGATCGAGTACCTGATGGGCGGG
GCTTATCGCTGCAACTACACGCGCAAGCGCTTCCGGACCCTCTACCACAACCTCTTCGGCCCCAAGAGGGATGATATTCCCTTGAGGCGAGGAAGAAAGA
CAACCAAGAAACGTGAAGAAGAGGTGGACATTGACTTGGATGATCCTGAGATCAACCACTTCCCCTTCCCTTTCCATGAGCTCATGGTGTGGGCTGTTCT
CATGAAGCGGCAGAAGATGGCCCTGTTCTTCTGGCAGCACGGTGAGGAGGCCATGGCCAAGGCCCTGGTGGCCTGCAAGCTCTGCAAAGCCATGGCTCAT
GAGGCCTCTGAGAACGACATGGTTGACGACATTTCCCAGGAGCTGAATCACAATTCCAGAGACTTTGGCCAGCTGGCTGTGGAGCTCCTGGACCAGTCCT
ACAAGCAGGACGAACAGCTGGCCATGAAACTGCTGACGTATGAGCTGAAGAACTGGAGCAACGCCACGTGCCTGCAGCTTGCCGTGGCTGCCAAACACCG
CGACTTCATCGCGCACACGTGCAGCCAGATGCTGCTCACCGACATGTGGATGGGCCGGCTCCGCATGCGCAAGAACTCAGGCCTCAAGGTAATTCTGGGA
ATTCTACTTCCTCCTTCAATTCTCAGCTTGGAGTTCAAGAACAAAGACGACATGCCCTATATGTCTCAGGCCCAGGAAATCCACCTCCAAGAGAAGGAGG
CAGAAGAACCAGAGAAGCCCACAAAGGAAAAAGAGGAAGAGGACATGGAGCTCACAGCAATGTTGGGACGAAACAACGGGGAGTCCTCCAGGAAGAAGGA
TGAAGAGGAAGTTCAGAGCAAGCACCGGTTAATCCCCCTCGGCAGAAAAATCTATGAATTCTACAATGCACCCATCGTGAAGTTCTGGTTCTACACACTG
GCGTATATCGGATACCTGATGCTCTTCAACTATATCGTGTTAGTGAAGATGGAACGCTGGCCGTCCACCCAGGAATGGATCGTAATCTCCTATATTTTCA
CCCTGGGAATAGAAAAGATGAGAGAGATTCTGATGTCAGAGCCAGGGAAGTTGCTACAGAAAGTGAAGGTATGGCTGCAGGAGTACTGGAATGTCACGGA
CCTCATCGCCATCCTTCTGTTTTCTGTCGGAATGATCCTTCGTCTCCAAGACCAGCCCTTCAGGAGTGACGGGAGGGTCATCTACTGCGTGAACATCATT
TACTGGTATATCCGTCTCCTAGACATCTTCGGCGTGAACAAGTATTTGGGCCCGTATGTAATGATGATTGGAAAAATGATGATAGACATGATGTACTTTG
TCATCATTATGCTGGTGGTTCTGATGAGCTTTGGGGTCGCCAGGCAAGCCATCCTTTTTCCCAATGAGGAGCCATCATGGAAACTGGCCAAGAACATCTT
CTACATGCCCTATTGGATGATTTATGGGGAAGTGTTTGCGGACCAGATAGACCCTCCCTGTGGACAGAATGAGACCCGAGAGGATGGTAAAATAATCCAG
CTGCCTCCCTGCAAGACAGGAGCTTGGATCGTGCCGGCCATCATGGCCTGCTACCTCTTAGTGGCAAACATCTTGCTGGTCAACCTCCTCATTGCTGTCT
TTAACAATACATTTTTTGAAGTAAAATCGATATCCAACCAAGTCTGGAAGTTTCAGAGGTATCAGCTCATCATGACTTTCCATGAAAGGCCAGTTCTGCC
CCCACCACTGATCATCTTCAGCCACATGACCATGATATTCCAGCACCTGTGCTGCCGATGGAGGAAACACGAGAGCGACCCGGATGAAAGGGACTACGGC
CTGAAACTCTTCATAACCGATGATGAGCTCAAGAAAGTACATGACTTTGAAGAGCAATGCATAGAAGAATACTTCAGAGAAAAGGATGATCGGTTCAACT
CATCTAATGATGAGAGGATACGGGTGACTTCAGAAAGGGTGGAGAACATGTCTATGCGGCTGGAGGAAGTCAACGAGAGAGAGCACTCCATGAAGGCTTC
ACTCCAGACCGTGGACATCCGGCTGGCGCAGCTGGAAGACCTTATCGGGCGCATGGCCACGGCCCTGGAGCGCCTGACAGGTCTGGAGCGGGCCGAGTCC
AACAAAATCCGCTCGAGGACCTCGTCAGACTGCACGGACGCCGCCTACATTGTCCGTCAGAGCAGCTTCAACAGCCAGGAAGGGAACACCTTCAAGCTCC
AAGAGAGTATAGACCCTGCAGGTGAGGAGACCATGTCCCCAACTTCTCCAACCTTAATGCCCCGTATGCGAAGCCATTCTTTCTATTCGGTCAATATGAA
AGACAAAGGTGGTATAGAAAAGTTGGAAAGTATTTTTAAAGAAAGGTCCCTGAGCCTACACCGGGCTACTAGTTCCCACTCTGTAGCAAAAGAACCCAAA
GCTCCTGCAGCCCCTGCCAACACCTTGGCCATTGTTCCTGATTCCAGAAGACCATCATCGTGTATAGACATCTATGTCTCTGCTATGGATGAGCTCCACT
GTGATATAGACCCTCTGGACAATTCCGTGAACATCCTTGGGCTGGGCGAGCCAAGCTTTTCAACTCCAGTACCTTCCACAGCCCCTTCAAGTAGTGCCTA
TGCAACACTTGCACCCACAGACAGACCTCCAAGCCGGAGCATTGATTTTGAGGACATCACCTCCATGGACACTAGATCTTTTTCTTCAGACTACACCCAC
CTCCCAGAATGCCAAAACCCCTGGGACTCAGAGCCTCCGATGTACCACACCATTGAGCGTTCCAAAAGTAGCCGCTACCTAGCCACCACACCCTTTCTTC
TAGAAGAGGCTCCCATTGTGAAATCTCATAGCTTTATGTTTTCCCCCTCAAGGAGCTATTATGCCAACTTTGGGGTGCCTGTAAAAACAGCAGAATACAC
AAGTATTACAGACTGTATTGACACAAGGTGTGTCAATGCCCCTCAAGCAATTGCGGACAGAGCTGCCTTCCCTGGAGGTCTTGGAGACAAAGTGGAGGAC
TTAACTTGCTGCCATCCAGAGCGAGAAGCAGAACTGAGTCACCCCAGCTCTGACAGTGAGGAGAATGAGGCCAAAGGCCGCAGAGCCACCATTGCAATAT
CCTCCCAGGAGGGTGATAACTCAGAGAGAACCCTGTCCAACAACATCACTGTTCCCAAGATAGAGCGCGCCAACAGCTACTCGGCAGAGGAGCCAAGTGC
GCCATATGCACACACCAGGAAGAGCTTCTCCATCAGTGACAAACTCGACAGGCAGCGGAACACAGCAAGCCTGCGAAATCCCTTCCAGAGAAGCAAGTCC
TCCAAGCCGGAGGGCCGAGGGGACAGCCTGTCCATGAGGAGACTGTCCAGAACATCGGCTTTCCAAAGCTTTGAAAGCAAGCACAACTAAACCTTCTTAA
TATCCGCCACAGAAGGCTCAAGAATCCAGCCCTAAAATTCTCTCCAACTCCAGTTTTTCCCCTTTCCTTGAATCATACCTGCTTTATTCTTAGCTGAGCA
AAACAAGCAATGCTTTGGGAGGTGTTAACTCAAAGGTGACTTCTGGGCCACAGATCAAGAAAGCATTTGATCTGACCCAGTGCCAGACACAGGGGATTTA
AGGCATGTTCACACTTGCTGGGCAGGGAGGGGGAAGAGAGGGAGAAGGAAGGGTTAGAGATGAATGTGTATCCGCAGTCACAGCAGAAAGCCATGAGAGC
AGGGGAAACAAGGGGCTTCGAGCACGCTCCATGCCAGGAGGCATCTGTTGATTTCTGACCATTATCAAGAGTTGTAGGATGCAGGGCTAAATTGCAAAAT
AAAATAAAATAGCCAGCGTACACAATGAGATATTCTAAACTTCCATTCTGTTTTCTTTTCACATTGGCTCCATCACTGGTGACTGATGAAGAGCATCCTC
TTTATTCAGTATAAGCCGGCAGCAAGCAGTTCTACCTAACGTCCCACATCCTTCTCATGCCAACACTTCTGTAATTGATCATTATAAAGAAAAAACAAGG
TAACAGTCATAGTTCACCTGTCTCTTATCTATTCACTTCTGGTGCCACAACTGTTTATCCTTTTTTGAAGAAAATAAGGGAACAGAAATGCCTTTTTGTA
TTGCAATCGAAATGAAAGAAGAGTTGATGTTAAAAAAACAAAAGTCAAGTGATTTATTATATACAGTGGGCGTTCAAGTCTAGTCGAGCAAGCTCAGGAG
AATGTAATTAAATAATTTTATATTTTTTAATTTATTTTGTATCTCACCTGTCATGGATGAATTCATTCACTGAATATGTAATATTGAACTTAAAAAAAAA
AAAAAAAAAA
  • refseq_TRPM3.F6 (forward primer)
  • refseq_TRPM3.R6 (reverse primer)
  • Single exon skipping

Frame 0

SCSKMKATGAAPGTAFASTQNQCSGSEILDRKS
IL*KRMCPHHTQHQRPP*VLLWASDRPACWPHPQ
YLRASE*EK*KSPLPK*HPV*KVVHQQTHSTQP
YGCFWDH*VPRRWPFQQSHVCASIF*YKT*SPL
TPDDQGMAVGASQASHLCPWGPAEL*TPAKTQAS
LWERAHQSSNDNWSVDIHWRG*HRCYSSCWRCL
EGSCL*VSRKDMHHRYCPLGNCGKPGGPHWKRC
CPAIPDHVQSHEQAHCSQQHAFPLHSG*QRDHWK
IWSRGETSKTTGKAYFTPEDKHKNRSRCSCGGT
HSGRRTQCDLDCFGVPSRHPSRASGCL*WEWTG
IGHPGLWA*ILRRRRTDK*IFEGPAVGDYTEDFH
IHSNPSSASVHHPHGVHEEEGIDYGISDGIRRT
PGH*FGYPDSFTQRSQCLGPRPTELSFSLEQSR
HRSQPDLYLRATVAGGISGASHVGCLSSGQSGFC
EITHREWSKHAPFSHHLQTRGIVQYETWALKYI
VPLGQGCQKGEPAPRLQNQPD*HRPGDRVPDGR
GLSLQLHAQALPDPLPQPLRPQEG*YSLEARKKD
NQET*RRGGH*LG*S*DQPLPLPFP*AHGVGCS
HEAAEDGPVLLAAR*GGHGQGPGGLQALQSHGS
*GL*ERHG*RHFPGAESQFQRLWPAGCGAPGPVL
QAGRTAGHETADV*AEELEQRHVPAACRGCQTP
RLHRAHVQPDAAHRHVDGPAPHAQELRPQGNSG
NSTSSFNSQLGVQEQRRHALYVSGPGNPPPREGG
RRTREAHKGKRGRGHGAHSNVGTKQRGVLQEEG
*RGSSEQAPVNPPRQKNL*ILQCTHREVLVLHT
GVYRIPDALQLYRVSEDGTLAVHPGMDRNLLYFH
PGNRKDERDSDVRAREVATESEGMAAGVLECHG
PHRHPSVFCRNDPSSPRPALQE*REGHLLREHH
LLVYPSPRHLRREQVFGPVCNDDWKNDDRHDVLC
HHYAGGSDELWGRQASHPFSQ*GAIMETGQEHL
LHALLDDLWGSVCGPDRPSLWTE*DPRGW*NNP
AASLQDRSLDRAGHHGLLPLSGKHLAGQPPHCCL
*QYIF*SKIDIQPSLEVSEVSAHHDFP*KASSA
PTTDHLQPHDHDIPAPVLPMEETRERPG*KGLR
PETLHNR**AQEST*L*RAMHRRILQRKG*SVQL
I***EDTGDFRKGGEHVYAAGGSQRERALHEGF
TPDRGHPAGAAGRPYRAHGHGPGAPDRSGAGRV
QQNPLEDLVRLHGRRLHCPSEQLQQPGREHLQAP
REYRPCR*GDHVPNFSNLNAPYAKPFFLFGQYE
RQRWYRKVGKYF*RKVPEPTPGY*FPLCSKRTQ
SSCSPCQHLGHCS*FQKTIIVYRHLCLCYG*APL
*YRPSGQFREHPWAGRAKLFNSSTFHSPFK*CL
CNTCTHRQTSKPEH*F*GHHLHGH*IFFFRLHP
PPRMPKPLGLRASDVPHH*AFQK*PLPSHHTLSS
RRGSHCEIS*LYVFPLKELLCQLWGACKNSRIH
KYYRLY*HKVCQCPSSNCGQSCLPWRSWRQSGG
LNLLPSRARSRTESPQL*Q*GE*GQRPQSHHCNI
LPGG**LRENPVQQHHCSQDRARQQLLGRGAKC
AICTHQEELLHQ*QTRQAAEHSKPAKSLPEKQV
LQAGGPRGQPVHEETVQNIGFPKL*KQAQLNLLN
IRHRRLKNPALKFSPTPVFPLSLNHTCFILS*A
KQAMLWEVLTQR*LLGHRSRKHLI*PSARHRGF
KACSHLLGREGEEREKEGLEMNVYPQSQQKAMRA
GETRGFEHAPCQEASVDF*PLSRVVGCRAKLQN
KIK*PAYTMRYSKLPFCFLFTLAPSLVTDEEHP
LYSV*AGSKQFYLTSHILLMPTLL*LIIIKKKQG
NSHSSPVSYLFTSGATTVYPFLKKIREQKCLFV
LQSK*KKS*C*KNKSQVIYYIQWAFKSSRASSG
ECN*IILYFLIYFVSHLSWMNSFTEYVILNLKKK
KKK

Frame 1

AAAK*KQQELLRGLLLPVPRISAQAQKSWIERA
FYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTP
SISVLQNEKNESRLSRNDIQSEKWSISKHTQLSP
TDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLL
HLMTKEWQLELPKLLISVHGGLQNFELQPKLKQ
VFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDAL
KDHASKSRGKICTIGIAPWGIVENQEDLIGRDV
VRPYQTMSNPMSKLTVLNSMHSHFILADNGTTG
KYGAEVKLRRQLEKHISLQKINTRIGQGVPVVAL
IVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTF
TYTRTQAQHLFIILMECMKKKELITVFRMGSEGH
QDIDLAILTALLKGANASAPDQLSLALAWNRVD
IARSQIFIYGQQWPVGSLEQAMLDALVLDRVDF
VKLLIENGVSMHRFLTISRLEELYNTRHGPSNTL
YHLVRDVKKGNLPPDYRISLIDIGLVIEYLMGG
AYRCNYTRKRFRTLYHNLFGPKRDDIPLRRGRK
TTKKREEEVDIDLDDPEINHFPFPFHELMVWAVL
MKRQKMALFFWQHGEEAMAKALVACKLCKAMAH
EASENDMVDDISQELNHNSRDFGQLAVELLDQS
YKQDEQLAMKLLTYELKNWSNATCLQLAVAAKHR
DFIAHTCSQMLLTDMWMGRLRMRKNSGLKVILG
ILLPPSILSLEFKNKDDMPYMSQAQEIHLQEKE
AEEPEKPTKEKEEEDMELTAMLGRNNGESSRKKD
EEEVQSKHRLIPLGRKIYEFYNAPIVKFWFYTL
AYIGYLMLFNYIVLVKMERWPSTQEWIVISYIF
TLGIEKMREILMSEPGKLLQKVKVWLQEYWNVTD
LIAILLFSVGMILRLQDQPFRSDGRVIYCVNII
YWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYF
VIIMLVVLMSFGVARQAILFPNEEPSWKLAKNIF
YMPYWMIYGEVFADQIDPPCGQNETREDGKIIQ
LPPCKTGAWIVPAIMACYLLVANILLVNLLIAV
FNNTFFEVKSISNQVWKFQRYQLIMTFHERPVLP
PPLIIFSHMTMIFQHLCCRWRKHESDPDERDYG
LKLFITDDELKKVHDFEEQCIEEYFREKDDRFN
SSNDERIRVTSERVENMSMRLEEVNEREHSMKAS
LQTVDIRLAQLEDLIGRMATALERLTGLERAES
NKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFKL
QESIDPAGEETMSPTSPTLMPRMRSHSFYSVNMK
DKGGIEKLESIFKERSLSLHRATSSHSVAKEPK
APAAPANTLAIVPDSRRPSSCIDIYVSAMDELH
CDIDPLDNSVNILGLGEPSFSTPVPSTAPSSSAY
ATLAPTDRPPSRSIDFEDITSMDTRSFSSDYTH
LPECQNPWDSEPPMYHTIERSKSSRYLATTPFL
LEEAPIVKSHSFMFSPSRSYYANFGVPVKTAEYT
SITDCIDTRCVNAPQAIADRAAFPGGLGDKVED
LTCCHPEREAELSHPSSDSEENEAKGRRATIAI
SSQEGDNSERTLSNNITVPKIERANSYSAEEPSA
PYAHTRKSFSISDKLDRQRNTASLRNPFQRSKS
SKPEGRGDSLSMRRLSRTSAFQSFESKHN*TFL
ISATEGSRIQP*NSLQLQFFPFP*IIPALFLAEQ
NKQCFGRC*LKGDFWATDQESI*SDPVPDTGDL
RHVHTCWAGRGKRGRRKG*R*MCIRSHSRKP*E
QGKQGASSTLHARRHLLISDHYQEL*DAGLNCKI
K*NSQRTQ*DILNFHSVFFSHWLHHW*LMKSIL
FIQYKPAASSST*RPTSFSCQHFCN*SL*RKNK
VTVIVHLSLIYSLLVPQLFILF*RK*GNRNAFLY
CNRNERRVDVKKTKVK*FIIYSGRSSLVEQAQE
NVIK*FYIF*FILYLTCHG*IHSLNM*Y*T*KK
KKK

Frame 2

LQQNESNRSCSGDCFCQYPESVLRLRNPG*KEH
FIKENVSTSYPAPKTPIGVAVGV**ASMLASPP
VSPCFRMRKMKVASPEMTSSLKSGPSANTLNSA
LRMLLGPLSSKEVAIPTKPCMCEYLLIQNLISSY
T**PRNGSWSFPSFSSLSMGACRTLNSSQNSSK
SLGKGSSKQQ*QLERGYSLEGLTQVLFVMLAMP
*RIMPLSLEERYAP*VLPPGELWKTRRTSLEEML
SGHTRPCPIP*ASSLFSTACIPTSFWLTTGPLE
NMEQR*NFEDNWKSIFHSRR*TQESVKVFLWWH
S*WKEDPM*SRLFWSTFETPLPCQWLSVMGVDGH
RTSWPLGINTQKKAD**MNL*GTSCW*LYRRLS
HTLEPKLSICSSSSWSA*RRRN*LRYFGWDQKD
TRTLIWLS*QLYSKEPMPRPQTN*A*L*PGTEST
SLAARSLFTGNSGRWDLWSKPCWMP*FWTEWIL
*NYS*RME*ACTVFSPSPD*RNCTIRDMGPQIH
CTTWSGMSKRGTCPQTTESA*LTSAW*SST*WAG
LIAATTRASASGPSTTTSSAPRGMIFP*GEEER
QPRNVKKRWTLTWMILRSTTSPSLSMSSWCGLF
S*SGRRWPCSSGSTVRRPWPRPWWPASSAKPWLM
RPLRTTWLTTFPRS*ITIPETLASWLWSSWTSP
TSRTNSWP*NC*RMS*RTGATPRACSLPWLPNT
ATSSRTRAARCCSPTCGWAGSACARTQASR*FWE
FYFLLQFSAWSSRTKTTCPICLRPRKSTSKRRR
QKNQRSPQRKKRKRTWSSQQCWDETTGSPPGRR
MKRKFRASTG*SPSAEKSMNSTMHPS*SSGSTHW
RISDT*CSSTISC**RWNAGRPPRNGS*SPIFS
PWE*KR*ERF*CQSQGSCYRK*RYGCRSTGMSR
TSSPSFCFLSE*SFVSKTSPSGVTGGSSTA*TSF
TGISVS*TSSA*TSIWARM***LEK***T*CTL
SSLCWWF**ALGSPGKPSFFPMRSHHGNWPRTS
STCPIG*FMGKCLRTR*TLPVDRMRPERMVK*SS
CLPARQELGSCRPSWPATS*WQTSCWSTSSLLS
LTIHFLK*NRYPTKSGSFRGISSS*LSMKGQFC
PHH*SSSAT*P*YSSTCAADGGNTRATRMKGTTA
*NSS*PMMSSRKYMTLKSNA*KNTSEKRMIGST
HLMMRGYG*LQKGWRTCLCGWRKSTRESTP*RL
HSRPWTSGWRSWKTLSGAWPRPWSA*QVWSGPSP
TKSARGPRQTARTPPTLSVRAASTARKGTPSSS
KRV*TLQVRRPCPQLLQP*CPVCEAILSIRSI*
KTKVV*KSWKVFLKKGP*AYTGLLVPTL*QKNPK
LLQPLPTPWPLFLIPEDHHRV*TSMSLLWMSST
VI*TLWTIP*TSLGWASQAFQLQYLPQPLQVVP
MQHLHPQTDLQAGALILRTSPPWTLDLFLQTTPT
SQNAKTPGTQSLRCTTPLSVPKVAAT*PPHPFF
*KRLPL*NLIALCFPPQGAIMPTLGCL*KQQNT
QVLQTVLTQGVSMPLKQLRTELPSLEVLETKWRT
*LAAIQSEKQN*VTPALTVRRMRPKAAEPPLQY
PPRRVITQREPCPTTSLFPR*SAPTATRQRSQV
RHMHTPGRASPSVTNSTGSGTQQACEIPSREASP
PSRRAEGTACP*GDCPEHRLSKALKASTTKPS*
YPPQKAQESSPKILSNSSFSPFLESYLLYS*LS
KTSNALGGVNSKVTSGPQIKKAFDLTQCQTQGI*
GMFTLAGQGGGREGEGRVRDECVSAVTAESHES
RGNKGLRARSMPGGIC*FLTIIKSCRMQG*IAK
*NKIASVHNEIF*TSILFSFHIGSITGD**RASS
LFSISRQQAVLPNVPHPSHANTSVIDHYKEKTR
*QS*FTCLLSIHFWCHNCLSFFEENKGTEMPFC
IAIEMKEELMLKKQKSSDLLYTVGVQV*SSKLRR
M*LNNFIFFNLFCISPVMDEFIH*ICNIELKKK
KKK

Sequence NM_024971

AGCTGCAGCAAAATGAAAGCAACAGGAGCTGCTCCGGGGACTGCTTTTGCCAGTACCCAGAATCAGTGCTCAGGCTCAGAAATCCTGGATAGAAAGAGCA
TTTTATAAAAGAGAATGTGTCCACATCATACCCAGCACCAAAGACCCCCATAGGTGTTGCTGTGGGCGTCTGATAGGCCAGCATGTTGGCCTCACCCCCA
GTATCTCCGTGCTTCAGAATGAGAAAAATGAAAGTCGCCTCTCCCGAAATGACATCCAGTCTGAAAAGTGGTCCATCAGCAAACACACTCAACTCAGCCC
TACGGATGCTTTTGGGACCATTGAGTTCCAAGGAGGTGGCCATTCCAACAAAGCCATGTATGTGCGAGTATCTTTTGATACAAAACCTGATCTCCTCTTA
CACCTGATGACCAAGGAATGGCAGTTGGAGCTTCCCAAGCTTCTCATCTCTGTCCATGGGGGCCTGCAGAACTTTGAACTCCAGCCAAAACTCAAGCAAG
TCTTTGGGAAAGGGCTCATCAAAGCAGCAATGACAACTGGAGCGTGGATATTCACTGGAGGGGTTAACACAGGTGTTATTCGTCATGTTGGCGATGCCTT
GAAGGATCATGCCTCTAAGTCTCGAGGAAAGATATGCACCATAGGTATTGCCCCCTGGGGAATTGTGGAAAACCAGGAGGACCTCATTGGAAGAGATGTT
GTCCGGCCATACCAGACCATGTCCAATCCCATGAGCAAGCTCACTGTTCTCAACAGCATGCATTCCCACTTCATTCTGGCTGACAACGGGACCACTGGAA
AATATGGAGCAGAGGTGAAACTTCGAAGACAACTGGAAAAGCATATTTCACTCCAGAAGATAAACACAAGAATCGGTCAAGGTGTTCCTGTGGTGGCACT
CATAGTGGAAGGAGGACCCAATGTGATCTCGATTGTTTTGGAGTACCTTCGAGACACCCCTCCCGTGCCAGTGGTTGTCTGTGATGGGAGTGGACGGGCA
TCGGACATCCTGGCCTTTGGGCATAAATACTCAGAAGAAGGCGGACTGATAAATGAATCTTTGAGGGACCAGCTGTTGGTGACTATACAGAAGACTTTCA
CATACACTCGAACCCAAGCTCAGCATCTGTTCATCATCCTCATGGAGTGCATGAAGAAGAAGGAATTGATTACGGTATTTCGGATGGGATCAGAAGGACA
CCAGGACATTGATTTGGCTATCCTGACAGCTTTACTCAAAGGAGCCAATGCCTCGGCCCCAGACCAACTGAGCTTAGCTTTAGCCTGGAACAGAGTCGAC
ATCGCTCGCAGCCAGATCTTTATTTACGGGCAACAGTGGCCGGTGGGATCTCTGGAGCAAGCCATGTTGGATGCCTTAGTTCTGGACAGAGTGGATTTTG
TGAAATTACTCATAGAGAATGGAGTAAGCATGCACCGTTTTCTCACCATCTCCAGACTAGAGGAATTGTACAATACGAGACATGGGCCCTCAAATACATT
GTACCACTTGGTCAGGGATGTCAAAAAGCGAGAGTATCCAGGTTTCGGTTGGATCTATTTTAAGGGGAACCTGCCCCCAGACTACAGAATCAGCCTGATT
GACATCGGCCTGGTGATCGAGTACCTGATGGGCGGGGCTTATCGCTGCAACTACACGCGCAAGCGCTTCCGGACCCTCTACCACAACCTCTTCGGCCCCA
AGAGGCCCAAAGCCTTGAAACTGCTGGGAATGGAGGATGATATTCCCTTGAGGCGAGGAAGAAAGACAACCAAGAAACGTGAAGAAGAGGTGGACATTGA
CTTGGATGATCCTGAGATCAACCACTTCCCCTTCCCTTTCCATGAGCTCATGGTGTGGGCTGTTCTCATGAAGCGGCAGAAGATGGCCCTGTTCTTCTGG
CAGCACGGTGAGGAGGCCATGGCCAAGGCCCTGGTGGCCTGCAAGCTCTGCAAAGCCATGGCTCATGAGGCCTCTGAGAACGACATGGTTGACGACATTT
CCCAGGAGCTGAATCACAATTCCAGAGACTTTGGCCAGCTGGCTGTGGAGCTCCTGGACCAGTCCTACAAGCAGGACGAACAGCTGGCCATGAAACTGCT
GACGTATGAGCTGAAGAACTGGAGCAACGCCACGTGCCTGCAGCTTGCCGTGGCTGCCAAACACCGCGACTTCATCGCGCACACGTGCAGCCAGATGCTG
CTCACCGACATGTGGATGGGCCGGCTCCGCATGCGCAAGAACTCAGGCCTCAAGGTAATTCTGGGAATTCTACTTCCTCCTTCAATTCTCAGCTTGGAGT
TCAAGAACAAAGACGACATGCCCTATATGTCTCAGGCCCAGGAAATCCACCTCCAAGAGAAGGAGGCAGAAGAACCAGAGAAGCCCACAAAGGAAAAAGA
GGAAGAGGACATGGAGCTCACAGCAATGTTGGGACGAAACAACGGGGAGTCCTCCAGGAAGAAGGATGAAGAGGAAGTTCAGAGCAAGCACCGGTTAATC
CCCCTCGGCAGAAAAATCTATGAATTCTACAATGCACCCATCGTGAAGTTCTGGTTCTACACACTGGCGTATATCGGATACCTGATGCTCTTCAACTATA
TCGTGTTAGTGAAGATGGAACGCTGGCCGTCCACCCAGGAATGGATCGTAATCTCCTATATTTTCACCCTGGGAATAGAAAAGATGAGAGAGATTCTGAT
GTCAGAGCCAGGGAAGTTGCTACAGAAAGTGAAGGTATGGCTGCAGGAGTACTGGAATGTCACGGACCTCATCGCCATCCTTCTGTTTTCTGTCGGAATG
ATCCTTCGTCTCCAAGACCAGCCCTTCAGGAGTGACGGGAGGGTCATCTACTGCGTGAACATCATTTACTGGTATATCCGTCTCCTAGACATCTTCGGCG
TGAACAAGTATTTGGGCCCGTATGTAATGATGATTGGAAAAATGATGATAGACATGATGTACTTTGTCATCATTATGCTGGTGGTTCTGATGAGCTTTGG
GGTCGCCAGGCAAGCCATCCTTTTTCCCAATGAGGAGCCATCATGGAAACTGGCCAAGAACATCTTCTACATGCCCTATTGGATGATTTATGGGGAAGTG
TTTGCGGACCAGATAGACCCTCCCTGTGGACAGAATGAGACCCGAGAGGATGGTAAAATAATCCAGCTGCCTCCCTGCAAGACAGGAGCTTGGATCGTGC
CGGCCATCATGGCCTGCTACCTCTTAGTGGCAAACATCTTGCTGGTCAACCTCCTCATTGCTGTCTTTAACAATACATTTTTTGAAGTAAAATCGATATC
CAACCAAGTCTGGAAGTTTCAGAGGTATCAGCTCATCATGACTTTCCATGAAAGGCCAGTTCTGCCCCCACCACTGATCATCTTCAGCCACATGACCATG
ATATTCCAGCACCTGTGCTGCCGATGGAGGAAACACGAGAGCGACCCGGATGAAAGGGACTACGGCCTGAAACTCTTCATAACCGATGATGAGCTCAAGA
AAGTACATGACTTTGAAGAGCAATGCATAGAAGAATACTTCAGAGAAAAGGATGATCGGTTCAACTCATCTAATGATGAGAGGATACGGGTGACTTCAGA
AAGGGTGGAGAACATGTCTATGCGGCTGGAGGAAGTCAACGAGAGAGAGCACTCCATGAAGGCTTCACTCCAGACCGTGGACATCCGGCTGGCGCAGCTG
GAAGACCTTATCGGGCGCATGGCCACGGCCCTGGAGCGCCTGACAGGTCTGGAGCGGGCCGAGTCCAACAAAATCCGCTCGAGGACCTCGTCAGACTGCA
CGGACGCCGCCTACATTGTCCGTCAGAGCAGCTTCAACAGCCAGGAAGGGAACACCTTCAAGCTCCAAGAGAGTATAGACCCTGCAGGTGAGGAGACCAT
GTCCCCAACTTCTCCAACCTTAATGCCCCGTATGCGAAGCCATTCTTTCTATTCGGTCAATATGAAAGACAAAGGTGGTATAGAAAAGTTGGAAAGTATT
TTTAAAGAAAGGTCCCTGAGCCTACACCGGGCTACTAGTTCCCACTCTGTAGCAAAAGAACCCAAAGCTCCTGCAGCCCCTGCCAACACCTTGGCCATTG
TTCCTGATTCCAGAAGACCATCATCGTGTATAGACATCTATGTCTCTGCTATGGATGAGCTCCACTGTGATATAGACCCTCTGGACAATTCCGTGAACAT
CCTTGGGCTGGGCGAGCCAAGCTTTTCAACTCCAGTACCTTCCACAGCCCCTTCAAGTAGTGCCTATGCAACACTTGCACCCACAGACAGACCTCCAAGC
CGGAGCATTGATTTTGAGGACATCACCTCCATGGACACTAGATCTTTTTCTTCAGACTACACCCACCTCCCAGAATGCCAAAACCCCTGGGACTCAGAGC
CTCCGATGTACCACACCATTGAGCGTTCCAAAAGTAGCCGCTACCTAGCCACCACACCCTTTCTTCTAGAAGAGGCTCCCATTGTGAAATCTCATAGCTT
TATGTTTTCCCCCTCAAGGAGCTATTATGCCAACTTTGGGGTGCCTGTAAAAACAGCAGAATACACAAGTATTACAGACTGTATTGACACAAGGTGTGTC
AATGCCCCTCAAGCAATTGCGGACAGAGCTGCCTTCCCTGGAGGTCTTGGAGACAAAGTGGAGGACTTAACTTGCTGCCATCCAGAGCGAGAAGCAGAAC
TGAGTCACCCCAGCTCTGACAGTGAGGAGAATGAGGCCAAAGGCCGCAGAGCCACCATTGCAATATCCTCCCAGGAGGGTGATAACTCAGAGAGAACCCT
GTCCAACAACATCACTGTTCCCAAGATAGAGCGCGCCAACAGCTACTCGGCAGAGGAGCCAAGTGCGCCATATGCACACACCAGGAAGAGCTTCTCCATC
AGTGACAAACTCGACAGGCAGCGGAACACAGCAAGCCTGCGAAATCCCTTCCAGAGAAGCAAGTCCTCCAAGCCGGAGGGCCGAGGGGACAGCCTGTCCA
TGAGGAGACTGTCCAGAACATCGGCTTTCCAAAGCTTTGAAAGCAAGCACAACTAAACCTTCTTAATATCCGCCACAGAAGGCTCAAGAATCCAGCCCTA
AAATTCTCTCCAACTCCAGTTTTTCCCCTTTCCTTGAATCATACCTGCTTTATTCTTAGCTGAGCAAAACAAGCAATGCTTTGGGAGGTGTTAACTCAAA
GGTGACTTCTGGGCCACAGATCAAGAAAGCATTTGATCTGACCCAGTGCCAGACACAGGGGATTTAAGGCATGTTCACACTTGCTGGGCAGGGAGGGGGA
AGAGAGGGAGAAGGAAGGGTTAGAGATGAATGTGTATCCGCAGTCACAGCAGAAAGCCATGAGAGCAGGGGAAACAAGGGGCTTCGAGCACGCTCCATGC
CAGGAGGCATCTGTTGATTTCTGACCATTATCAAGAGTTGTAGGATGCAGGGCTAAATTGCAAAATAAAATAAAATAGCCAGCGTACACAATGAGATATT
CTAAACTTCCATTCTGTTTTCTTTTCACATTGGCTCCATCACTGGTGACTGATGAAGAGCATCCTCTTTATTCAGTATAAGCCGGCAGCAAGCAGTTCTA
CCTAACGTCCCACATCCTTCTCATGCCAACACTTCTGTAATTGATCATTATAAAGAAAAAACAAGGTAACAGTCATAGTTCACCTGTCTCTTATCTATTC
ACTTCTGGTGCCACAACTGTTTATCCTTTTTTGAAGAAAATAAGGGAACAGAAATGCCTTTTTGTATTGCAATCGAAATGAAAGAAGAGTTGATGTTAAA
AAAACAAAAGTCAAGTGATTTATTATATACAGTGGGCGTTCAAGTCTAGTCGAGCAAGCTCAGGAGAATGTAATTAAATAATTTTATATTTTTTAATTTA
TTTTGTATCTCACCTGTCATGGATGAATTCATTCACTGAATATGTAATATTGAACTTAAAAAAAAAAAAAAAAAAA
  • refseq_TRPM3.F6 (forward primer)
  • refseq_TRPM3.R6 (reverse primer)
  • Single exon skipping

Frame 0

SCSKMKATGAAPGTAFASTQNQCSGSEILDRKS
IL*KRMCPHHTQHQRPP*VLLWASDRPACWPHPQ
YLRASE*EK*KSPLPK*HPV*KVVHQQTHSTQP
YGCFWDH*VPRRWPFQQSHVCASIF*YKT*SPL
TPDDQGMAVGASQASHLCPWGPAEL*TPAKTQAS
LWERAHQSSNDNWSVDIHWRG*HRCYSSCWRCL
EGSCL*VSRKDMHHRYCPLGNCGKPGGPHWKRC
CPAIPDHVQSHEQAHCSQQHAFPLHSG*QRDHWK
IWSRGETSKTTGKAYFTPEDKHKNRSRCSCGGT
HSGRRTQCDLDCFGVPSRHPSRASGCL*WEWTG
IGHPGLWA*ILRRRRTDK*IFEGPAVGDYTEDFH
IHSNPSSASVHHPHGVHEEEGIDYGISDGIRRT
PGH*FGYPDSFTQRSQCLGPRPTELSFSLEQSR
HRSQPDLYLRATVAGGISGASHVGCLSSGQSGFC
EITHREWSKHAPFSHHLQTRGIVQYETWALKYI
VPLGQGCQKARVSRFRLDLF*GEPAPRLQNQPD
*HRPGDRVPDGRGLSLQLHAQALPDPLPQPLRPQ
EAQSLETAGNGG*YSLEARKKDNQET*RRGGH*
LG*S*DQPLPLPFP*AHGVGCSHEAAEDGPVLL
AAR*GGHGQGPGGLQALQSHGS*GL*ERHG*RHF
PGAESQFQRLWPAGCGAPGPVLQAGRTAGHETA
DV*AEELEQRHVPAACRGCQTPRLHRAHVQPDA
AHRHVDGPAPHAQELRPQGNSGNSTSSFNSQLGV
QEQRRHALYVSGPGNPPPREGGRRTREAHKGKR
GRGHGAHSNVGTKQRGVLQEEG*RGSSEQAPVN
PPRQKNL*ILQCTHREVLVLHTGVYRIPDALQLY
RVSEDGTLAVHPGMDRNLLYFHPGNRKDERDSD
VRAREVATESEGMAAGVLECHGPHRHPSVFCRN
DPSSPRPALQE*REGHLLREHHLLVYPSPRHLRR
EQVFGPVCNDDWKNDDRHDVLCHHYAGGSDELW
GRQASHPFSQ*GAIMETGQEHLLHALLDDLWGS
VCGPDRPSLWTE*DPRGW*NNPAASLQDRSLDRA
GHHGLLPLSGKHLAGQPPHCCL*QYIF*SKIDI
QPSLEVSEVSAHHDFP*KASSAPTTDHLQPHDH
DIPAPVLPMEETRERPG*KGLRPETLHNR**AQE
ST*L*RAMHRRILQRKG*SVQLI***EDTGDFR
KGGEHVYAAGGSQRERALHEGFTPDRGHPAGAA
GRPYRAHGHGPGAPDRSGAGRVQQNPLEDLVRLH
GRRLHCPSEQLQQPGREHLQAPREYRPCR*GDH
VPNFSNLNAPYAKPFFLFGQYERQRWYRKVGKY
F*RKVPEPTPGY*FPLCSKRTQSSCSPCQHLGHC
S*FQKTIIVYRHLCLCYG*APL*YRPSGQFREH
PWAGRAKLFNSSTFHSPFK*CLCNTCTHRQTSK
PEH*F*GHHLHGH*IFFFRLHPPPRMPKPLGLRA
SDVPHH*AFQK*PLPSHHTLSSRRGSHCEIS*L
YVFPLKELLCQLWGACKNSRIHKYYRLY*HKVC
QCPSSNCGQSCLPWRSWRQSGGLNLLPSRARSRT
ESPQL*Q*GE*GQRPQSHHCNILPGG**LRENP
VQQHHCSQDRARQQLLGRGAKCAICTHQEELLH
Q*QTRQAAEHSKPAKSLPEKQVLQAGGPRGQPVH
EETVQNIGFPKL*KQAQLNLLNIRHRRLKNPAL
KFSPTPVFPLSLNHTCFILS*AKQAMLWEVLTQ
R*LLGHRSRKHLI*PSARHRGFKACSHLLGREGE
EREKEGLEMNVYPQSQQKAMRAGETRGFEHAPC
QEASVDF*PLSRVVGCRAKLQNKIK*PAYTMRY
SKLPFCFLFTLAPSLVTDEEHPLYSV*AGSKQFY
LTSHILLMPTLL*LIIIKKKQGNSHSSPVSYLF
TSGATTVYPFLKKIREQKCLFVLQSK*KKS*C*
KNKSQVIYYIQWAFKSSRASSGECN*IILYFLIY
FVSHLSWMNSFTEYVILNLKKKKKK

Frame 1

AAAK*KQQELLRGLLLPVPRISAQAQKSWIERA
FYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTP
SISVLQNEKNESRLSRNDIQSEKWSISKHTQLSP
TDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLL
HLMTKEWQLELPKLLISVHGGLQNFELQPKLKQ
VFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDAL
KDHASKSRGKICTIGIAPWGIVENQEDLIGRDV
VRPYQTMSNPMSKLTVLNSMHSHFILADNGTTG
KYGAEVKLRRQLEKHISLQKINTRIGQGVPVVAL
IVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTF
TYTRTQAQHLFIILMECMKKKELITVFRMGSEGH
QDIDLAILTALLKGANASAPDQLSLALAWNRVD
IARSQIFIYGQQWPVGSLEQAMLDALVLDRVDF
VKLLIENGVSMHRFLTISRLEELYNTRHGPSNTL
YHLVRDVKKREYPGFGWIYFKGNLPPDYRISLI
DIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGP
KRPKALKLLGMEDDIPLRRGRKTTKKREEEVDID
LDDPEINHFPFPFHELMVWAVLMKRQKMALFFW
QHGEEAMAKALVACKLCKAMAHEASENDMVDDI
SQELNHNSRDFGQLAVELLDQSYKQDEQLAMKLL
TYELKNWSNATCLQLAVAAKHRDFIAHTCSQML
LTDMWMGRLRMRKNSGLKVILGILLPPSILSLE
FKNKDDMPYMSQAQEIHLQEKEAEEPEKPTKEKE
EEDMELTAMLGRNNGESSRKKDEEEVQSKHRLI
PLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNY
IVLVKMERWPSTQEWIVISYIFTLGIEKMREILM
SEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGM
ILRLQDQPFRSDGRVIYCVNIIYWYIRLLDIFG
VNKYLGPYVMMIGKMMIDMMYFVIIMLVVLMSFG
VARQAILFPNEEPSWKLAKNIFYMPYWMIYGEV
FADQIDPPCGQNETREDGKIIQLPPCKTGAWIV
PAIMACYLLVANILLVNLLIAVFNNTFFEVKSIS
NQVWKFQRYQLIMTFHERPVLPPPLIIFSHMTM
IFQHLCCRWRKHESDPDERDYGLKLFITDDELK
KVHDFEEQCIEEYFREKDDRFNSSNDERIRVTSE
RVENMSMRLEEVNEREHSMKASLQTVDIRLAQL
EDLIGRMATALERLTGLERAESNKIRSRTSSDC
TDAAYIVRQSSFNSQEGNTFKLQESIDPAGEETM
SPTSPTLMPRMRSHSFYSVNMKDKGGIEKLESI
FKERSLSLHRATSSHSVAKEPKAPAAPANTLAI
VPDSRRPSSCIDIYVSAMDELHCDIDPLDNSVNI
LGLGEPSFSTPVPSTAPSSSAYATLAPTDRPPS
RSIDFEDITSMDTRSFSSDYTHLPECQNPWDSE
PPMYHTIERSKSSRYLATTPFLLEEAPIVKSHSF
MFSPSRSYYANFGVPVKTAEYTSITDCIDTRCV
NAPQAIADRAAFPGGLGDKVEDLTCCHPEREAE
LSHPSSDSEENEAKGRRATIAISSQEGDNSERTL
SNNITVPKIERANSYSAEEPSAPYAHTRKSFSI
SDKLDRQRNTASLRNPFQRSKSSKPEGRGDSLS
MRRLSRTSAFQSFESKHN*TFLISATEGSRIQP*
NSLQLQFFPFP*IIPALFLAEQNKQCFGRC*LK
GDFWATDQESI*SDPVPDTGDLRHVHTCWAGRG
KRGRRKG*R*MCIRSHSRKP*EQGKQGASSTLHA
RRHLLISDHYQEL*DAGLNCKIK*NSQRTQ*DI
LNFHSVFFSHWLHHW*LMKSILFIQYKPAASSS
T*RPTSFSCQHFCN*SL*RKNKVTVIVHLSLIYS
LLVPQLFILF*RK*GNRNAFLYCNRNERRVDVK
KTKVK*FIIYSGRSSLVEQAQENVIK*FYIF*F
ILYLTCHG*IHSLNM*Y*T*KKKKK

Frame 2

LQQNESNRSCSGDCFCQYPESVLRLRNPG*KEH
FIKENVSTSYPAPKTPIGVAVGV**ASMLASPP
VSPCFRMRKMKVASPEMTSSLKSGPSANTLNSA
LRMLLGPLSSKEVAIPTKPCMCEYLLIQNLISSY
T**PRNGSWSFPSFSSLSMGACRTLNSSQNSSK
SLGKGSSKQQ*QLERGYSLEGLTQVLFVMLAMP
*RIMPLSLEERYAP*VLPPGELWKTRRTSLEEML
SGHTRPCPIP*ASSLFSTACIPTSFWLTTGPLE
NMEQR*NFEDNWKSIFHSRR*TQESVKVFLWWH
S*WKEDPM*SRLFWSTFETPLPCQWLSVMGVDGH
RTSWPLGINTQKKAD**MNL*GTSCW*LYRRLS
HTLEPKLSICSSSSWSA*RRRN*LRYFGWDQKD
TRTLIWLS*QLYSKEPMPRPQTN*A*L*PGTEST
SLAARSLFTGNSGRWDLWSKPCWMP*FWTEWIL
*NYS*RME*ACTVFSPSPD*RNCTIRDMGPQIH
CTTWSGMSKSESIQVSVGSILRGTCPQTTESA*L
TSAW*SST*WAGLIAATTRASASGPSTTTSSAP
RGPKP*NCWEWRMIFP*GEEERQPRNVKKRWTL
TWMILRSTTSPSLSMSSWCGLFS*SGRRWPCSSG
STVRRPWPRPWWPASSAKPWLMRPLRTTWLTTF
PRS*ITIPETLASWLWSSWTSPTSRTNSWP*NC
*RMS*RTGATPRACSLPWLPNTATSSRTRAARCC
SPTCGWAGSACARTQASR*FWEFYFLLQFSAWS
SRTKTTCPICLRPRKSTSKRRRQKNQRSPQRKK
RKRTWSSQQCWDETTGSPPGRRMKRKFRASTG*S
PSAEKSMNSTMHPS*SSGSTHWRISDT*CSSTI
SC**RWNAGRPPRNGS*SPIFSPWE*KR*ERF*
CQSQGSCYRK*RYGCRSTGMSRTSSPSFCFLSE*
SFVSKTSPSGVTGGSSTA*TSFTGISVS*TSSA
*TSIWARM***LEK***T*CTLSSLCWWF**AL
GSPGKPSFFPMRSHHGNWPRTSSTCPIG*FMGKC
LRTR*TLPVDRMRPERMVK*SSCLPARQELGSC
RPSWPATS*WQTSCWSTSSLLSLTIHFLK*NRY
PTKSGSFRGISSS*LSMKGQFCPHH*SSSAT*P*
YSSTCAADGGNTRATRMKGTTA*NSS*PMMSSR
KYMTLKSNA*KNTSEKRMIGSTHLMMRGYG*LQ
KGWRTCLCGWRKSTRESTP*RLHSRPWTSGWRSW
KTLSGAWPRPWSA*QVWSGPSPTKSARGPRQTA
RTPPTLSVRAASTARKGTPSSSKRV*TLQVRRP
CPQLLQP*CPVCEAILSIRSI*KTKVV*KSWKVF
LKKGP*AYTGLLVPTL*QKNPKLLQPLPTPWPL
FLIPEDHHRV*TSMSLLWMSSTVI*TLWTIP*T
SLGWASQAFQLQYLPQPLQVVPMQHLHPQTDLQA
GALILRTSPPWTLDLFLQTTPTSQNAKTPGTQS
LRCTTPLSVPKVAAT*PPHPFF*KRLPL*NLIA
LCFPPQGAIMPTLGCL*KQQNTQVLQTVLTQGVS
MPLKQLRTELPSLEVLETKWRT*LAAIQSEKQN
*VTPALTVRRMRPKAAEPPLQYPPRRVITQREP
CPTTSLFPR*SAPTATRQRSQVRHMHTPGRASPS
VTNSTGSGTQQACEIPSREASPPSRRAEGTACP
*GDCPEHRLSKALKASTTKPS*YPPQKAQESSP
KILSNSSFSPFLESYLLYS*LSKTSNALGGVNSK
VTSGPQIKKAFDLTQCQTQGI*GMFTLAGQGGG
REGEGRVRDECVSAVTAESHESRGNKGLRARSM
PGGIC*FLTIIKSCRMQG*IAK*NKIASVHNEIF
*TSILFSFHIGSITGD**RASSLFSISRQQAVL
PNVPHPSHANTSVIDHYKEKTR*QS*FTCLLSI
HFWCHNCLSFFEENKGTEMPFCIAIEMKEELMLK
KQKSSDLLYTVGVQV*SSKLRRM*LNNFIFFNL
FCISPVMDEFIH*ICNIELKKKKKK

Sequence NM_206945

AGCTGCAGCAAAATGAAAGCAACAGGAGCTGCTCCGGGGACTGCTTTTGCCAGTACCCAGAATCAGTGCTCAGGCTCAGAAATCCTGGATAGAAAGAGCA
TTTTATAAAAGAGAATGTGTCCACATCATACCCAGCACCAAAGACCCCCATAGGTGTTGCTGTGGGCGTCTGATAGGCCAGCATGTTGGCCTCACCCCCA
GTATCTCCGTGCTTCAGAATGAGAAAAATGAAAGTCGCCTCTCCCGAAATGACATCCAGTCTGAAAAGTGGTCCATCAGCAAACACACTCAACTCAGCCC
TACGGATGCTTTTGGGACCATTGAGTTCCAAGGAGGTGGCCATTCCAACAAAGCCATGTATGTGCGAGTATCTTTTGATACAAAACCTGATCTCCTCTTA
CACCTGATGACCAAGGAATGGCAGTTGGAGCTTCCCAAGCTTCTCATCTCTGTCCATGGGGGCCTGCAGAACTTTGAACTCCAGCCAAAACTCAAGCAAG
TCTTTGGGAAAGGGCTCATCAAAGCAGCAATGACAACTGGAGCGTGGATATTCACTGGAGGGGTTAACACAGGTGTTATTCGTCATGTTGGCGATGCCTT
GAAGGATCATGCCTCTAAGTCTCGAGGAAAGATATGCACCATAGGTATTGCCCCCTGGGGAATTGTGGAAAACCAGGAGGACCTCATTGGAAGAGATGTT
GTCCGGCCATACCAGACCATGTCCAATCCCATGAGCAAGCTCACTGTTCTCAACAGCATGCATTCCCACTTCATTCTGGCTGACAACGGGACCACTGGAA
AATATGGAGCAGAGGTGAAACTTCGAAGACAACTGGAAAAGCATATTTCACTCCAGAAGATAAACACAAGAATCGGTCAAGGTGTTCCTGTGGTGGCACT
CATAGTGGAAGGAGGACCCAATGTGATCTCGATTGTTTTGGAGTACCTTCGAGACACCCCTCCCGTGCCAGTGGTTGTCTGTGATGGGAGTGGACGGGCA
TCGGACATCCTGGCCTTTGGGCATAAATACTCAGAAGAAGGCGGACTGATAAATGAATCTTTGAGGGACCAGCTGTTGGTGACTATACAGAAGACTTTCA
CATACACTCGAACCCAAGCTCAGCATCTGTTCATCATCCTCATGGAGTGCATGAAGAAGAAGGAATTGATTACGGTATTTCGGATGGGATCAGAAGGACA
CCAGGACATTGATTTGGCTATCCTGACAGCTTTACTCAAAGGAGCCAATGCCTCGGCCCCAGACCAACTGAGCTTAGCTTTAGCCTGGAACAGAGTCGAC
ATCGCTCGCAGCCAGATCTTTATTTACGGGCAACAGTGGCCGGTGGGATCTCTGGAGCAAGCCATGTTGGATGCCTTAGTTCTGGACAGAGTGGATTTTG
TGAAATTACTCATAGAGAATGGAGTAAGCATGCACCGTTTTCTCACCATCTCCAGACTAGAGGAATTGTACAATACGAGACATGGGCCCTCAAATACATT
GTACCACTTGGTCAGGGATGTCAAAAAGCGAGAGTATCCAGGTTTCGGTTGGATCTATTTTAAGGGGAACCTGCCCCCAGACTACAGAATCAGCCTGATT
GACATCGGCCTGGTGATCGAGTACCTGATGGGCGGGGCTTATCGCTGCAACTACACGCGCAAGCGCTTCCGGACCCTCTACCACAACCTCTTCGGCCCCA
AGAGGGATGATATTCCCTTGAGGCGAGGAAGAAAGACAACCAAGAAACGTGAAGAAGAGGTGGACATTGACTTGGATGATCCTGAGATCAACCACTTCCC
CTTCCCTTTCCATGAGCTCATGGTGTGGGCTGTTCTCATGAAGCGGCAGAAGATGGCCCTGTTCTTCTGGCAGCACGGTGAGGAGGCCATGGCCAAGGCC
CTGGTGGCCTGCAAGCTCTGCAAAGCCATGGCTCATGAGGCCTCTGAGAACGACATGGTTGACGACATTTCCCAGGAGCTGAATCACAATTCCAGAGACT
TTGGCCAGCTGGCTGTGGAGCTCCTGGACCAGTCCTACAAGCAGGACGAACAGCTGGCCATGAAACTGCTGACGTATGAGCTGAAGAACTGGAGCAACGC
CACGTGCCTGCAGCTTGCCGTGGCTGCCAAACACCGCGACTTCATCGCGCACACGTGCAGCCAGATGCTGCTCACCGACATGTGGATGGGCCGGCTCCGC
ATGCGCAAGAACTCAGGCCTCAAGGTAATTCTGGGAATTCTACTTCCTCCTTCAATTCTCAGCTTGGAGTTCAAGAACAAAGACGACATGCCCTATATGT
CTCAGGCCCAGGAAATCCACCTCCAAGAGAAGGAGGCAGAAGAACCAGAGAAGCCCACAAAGGAAAAAGAGGAAGAGGACATGGAGCTCACAGCAATGTT
GGGACGAAACAACGGGGAGTCCTCCAGGAAGAAGGATGAAGAGGAAGTTCAGAGCAAGCACCGGTTAATCCCCCTCGGCAGAAAAATCTATGAATTCTAC
AATGCACCCATCGTGAAGTTCTGGTTCTACACACTGGCGTATATCGGATACCTGATGCTCTTCAACTATATCGTGTTAGTGAAGATGGAACGCTGGCCGT
CCACCCAGGAATGGATCGTAATCTCCTATATTTTCACCCTGGGAATAGAAAAGATGAGAGAGATTCTGATGTCAGAGCCAGGGAAGTTGCTACAGAAAGT
GAAGGTATGGCTGCAGGAGTACTGGAATGTCACGGACCTCATCGCCATCCTTCTGTTTTCTGTCGGAATGATCCTTCGTCTCCAAGACCAGCCCTTCAGG
AGTGACGGGAGGGTCATCTACTGCGTGAACATCATTTACTGGTATATCCGTCTCCTAGACATCTTCGGCGTGAACAAGTATTTGGGCCCGTATGTAATGA
TGATTGGAAAAATGATGATAGACATGATGTACTTTGTCATCATTATGCTGGTGGTTCTGATGAGCTTTGGGGTCGCCAGGCAAGCCATCCTTTTTCCCAA
TGAGGAGCCATCATGGAAACTGGCCAAGAACATCTTCTACATGCCCTATTGGATGATTTATGGGGAAGTGTTTGCGGACCAGATAGACCCTCCCTGTGGA
CAGAATGAGACCCGAGAGGATGGTAAAATAATCCAGCTGCCTCCCTGCAAGACAGGAGCTTGGATCGTGCCGGCCATCATGGCCTGCTACCTCTTAGTGG
CAAACATCTTGCTGGTCAACCTCCTCATTGCTGTCTTTAACAATACATTTTTTGAAGTAAAATCGATATCCAACCAAGTCTGGAAGTTTCAGAGGTATCA
GCTCATCATGACTTTCCATGAAAGGCCAGTTCTGCCCCCACCACTGATCATCTTCAGCCACATGACCATGATATTCCAGCACCTGTGCTGCCGATGGAGG
AAACACGAGAGCGACCCGGATGAAAGGGACTACGGCCTGAAACTCTTCATAACCGATGATGAGCTCAAGAAAGTACATGACTTTGAAGAGCAATGCATAG
AAGAATACTTCAGAGAAAAGGATGATCGGTTCAACTCATCTAATGATGAGAGGATACGGGTGACTTCAGAAAGGGTGGAGAACATGTCTATGCGGCTGGA
GGAAGTCAACGAGAGAGAGCACTCCATGAAGGCTTCACTCCAGACCGTGGACATCCGGCTGGCGCAGCTGGAAGACCTTATCGGGCGCATGGCCACGGCC
CTGGAGCGCCTGACAGGTCTGGAGCGGGCCGAGTCCAACAAAATCCGCTCGAGGACCTCGTCAGACTGCACGGACGCCGCCTACATTGTCCGTCAGAGCA
GCTTCAACAGCCAGGAAGGGAACACCTTCAAGCTCCAAGAGAGTATAGACCCTGCAGGTGAGGAGACCATGTCCCCAACTTCTCCAACCTTAATGCCCCG
TATGCGAAGCCATTCTTTCTATTCGGTCAATATGAAAGACAAAGGTGGTATAGAAAAGTTGGAAAGTATTTTTAAAGAAAGGTCCCTGAGCCTACACCGG
GCTACTAGTTCCCACTCTGTAGCAAAAGAACCCAAAGCTCCTGCAGCCCCTGCCAACACCTTGGCCATTGTTCCTGATTCCAGAAGACCATCATCGTGTA
TAGACATCTATGTCTCTGCTATGGATGAGCTCCACTGTGATATAGACCCTCTGGACAATTCCGTGAACATCCTTGGGCTGGGCGAGCCAAGCTTTTCAAC
TCCAGTACCTTCCACAGCCCCTTCAAGTAGTGCCTATGCAACACTTGCACCCACAGACAGACCTCCAAGCCGGAGCATTGATTTTGAGGACATCACCTCC
ATGGACACTAGATCTTTTTCTTCAGACTACACCCACCTCCCAGAATGCCAAAACCCCTGGGACTCAGAGCCTCCGATGTACCACACCATTGAGCGTTCCA
AAAGTAGCCGCTACCTAGCCACCACACCCTTTCTTCTAGAAGAGGCTCCCATTGTGAAATCTCATAGCTTTATGTTTTCCCCCTCAAGGAGCTATTATGC
CAACTTTGGGGTGCCTGTAAAAACAGCAGAATACACAAGTATTACAGACTGTATTGACACAAGGTGTGTCAATGCCCCTCAAGCAATTGCGGACAGAGCT
GCCTTCCCTGGAGGTCTTGGAGACAAAGTGGAGGACTTAACTTGCTGCCATCCAGAGCGAGAAGCAGAACTGAGTCACCCCAGCTCTGACAGTGAGGAGA
ATGAGGCCAAAGGCCGCAGAGCCACCATTGCAATATCCTCCCAGGAGGGTGATAACTCAGAGAGAACCCTGTCCAACAACATCACTGTTCCCAAGATAGA
GCGCGCCAACAGCTACTCGGCAGAGGAGCCAAGTGCGCCATATGCACACACCAGGAAGAGCTTCTCCATCAGTGACAAACTCGACAGGCAGCGGAACACA
GCAAGCCTGCGAAATCCCTTCCAGAGAAGCAAGTCCTCCAAGCCGGAGGGCCGAGGGGACAGCCTGTCCATGAGGAGACTGTCCAGAACATCGGCTTTCC
AAAGCTTTGAAAGCAAGCACAACTAAACCTTCTTAATATCCGCCACAGAAGGCTCAAGAATCCAGCCCTAAAATTCTCTCCAACTCCAGTTTTTCCCCTT
TCCTTGAATCATACCTGCTTTATTCTTAGCTGAGCAAAACAAGCAATGCTTTGGGAGGTGTTAACTCAAAGGTGACTTCTGGGCCACAGATCAAGAAAGC
ATTTGATCTGACCCAGTGCCAGACACAGGGGATTTAAGGCATGTTCACACTTGCTGGGCAGGGAGGGGGAAGAGAGGGAGAAGGAAGGGTTAGAGATGAA
TGTGTATCCGCAGTCACAGCAGAAAGCCATGAGAGCAGGGGAAACAAGGGGCTTCGAGCACGCTCCATGCCAGGAGGCATCTGTTGATTTCTGACCATTA
TCAAGAGTTGTAGGATGCAGGGCTAAATTGCAAAATAAAATAAAATAGCCAGCGTACACAATGAGATATTCTAAACTTCCATTCTGTTTTCTTTTCACAT
TGGCTCCATCACTGGTGACTGATGAAGAGCATCCTCTTTATTCAGTATAAGCCGGCAGCAAGCAGTTCTACCTAACGTCCCACATCCTTCTCATGCCAAC
ACTTCTGTAATTGATCATTATAAAGAAAAAACAAGGTAACAGTCATAGTTCACCTGTCTCTTATCTATTCACTTCTGGTGCCACAACTGTTTATCCTTTT
TTGAAGAAAATAAGGGAACAGAAATGCCTTTTTGTATTGCAATCGAAATGAAAGAAGAGTTGATGTTAAAAAAACAAAAGTCAAGTGATTTATTATATAC
AGTGGGCGTTCAAGTCTAGTCGAGCAAGCTCAGGAGAATGTAATTAAATAATTTTATATTTTTTAATTTATTTTGTATCTCACCTGTCATGGATGAATTC
ATTCACTGAATATGTAATATTGAACTTAAAAAAAAAAAAAAAAAAA
  • refseq_TRPM3.F6 (forward primer)
  • refseq_TRPM3.R6 (reverse primer)
  • Single exon skipping

Frame 0

SCSKMKATGAAPGTAFASTQNQCSGSEILDRKS
IL*KRMCPHHTQHQRPP*VLLWASDRPACWPHPQ
YLRASE*EK*KSPLPK*HPV*KVVHQQTHSTQP
YGCFWDH*VPRRWPFQQSHVCASIF*YKT*SPL
TPDDQGMAVGASQASHLCPWGPAEL*TPAKTQAS
LWERAHQSSNDNWSVDIHWRG*HRCYSSCWRCL
EGSCL*VSRKDMHHRYCPLGNCGKPGGPHWKRC
CPAIPDHVQSHEQAHCSQQHAFPLHSG*QRDHWK
IWSRGETSKTTGKAYFTPEDKHKNRSRCSCGGT
HSGRRTQCDLDCFGVPSRHPSRASGCL*WEWTG
IGHPGLWA*ILRRRRTDK*IFEGPAVGDYTEDFH
IHSNPSSASVHHPHGVHEEEGIDYGISDGIRRT
PGH*FGYPDSFTQRSQCLGPRPTELSFSLEQSR
HRSQPDLYLRATVAGGISGASHVGCLSSGQSGFC
EITHREWSKHAPFSHHLQTRGIVQYETWALKYI
VPLGQGCQKARVSRFRLDLF*GEPAPRLQNQPD
*HRPGDRVPDGRGLSLQLHAQALPDPLPQPLRPQ
EG*YSLEARKKDNQET*RRGGH*LG*S*DQPLP
LPFP*AHGVGCSHEAAEDGPVLLAAR*GGHGQG
PGGLQALQSHGS*GL*ERHG*RHFPGAESQFQRL
WPAGCGAPGPVLQAGRTAGHETADV*AEELEQR
HVPAACRGCQTPRLHRAHVQPDAAHRHVDGPAP
HAQELRPQGNSGNSTSSFNSQLGVQEQRRHALYV
SGPGNPPPREGGRRTREAHKGKRGRGHGAHSNV
GTKQRGVLQEEG*RGSSEQAPVNPPRQKNL*IL
QCTHREVLVLHTGVYRIPDALQLYRVSEDGTLAV
HPGMDRNLLYFHPGNRKDERDSDVRAREVATES
EGMAAGVLECHGPHRHPSVFCRNDPSSPRPALQ
E*REGHLLREHHLLVYPSPRHLRREQVFGPVCND
DWKNDDRHDVLCHHYAGGSDELWGRQASHPFSQ
*GAIMETGQEHLLHALLDDLWGSVCGPDRPSLW
TE*DPRGW*NNPAASLQDRSLDRAGHHGLLPLSG
KHLAGQPPHCCL*QYIF*SKIDIQPSLEVSEVS
AHHDFP*KASSAPTTDHLQPHDHDIPAPVLPME
ETRERPG*KGLRPETLHNR**AQEST*L*RAMHR
RILQRKG*SVQLI***EDTGDFRKGGEHVYAAG
GSQRERALHEGFTPDRGHPAGAAGRPYRAHGHG
PGAPDRSGAGRVQQNPLEDLVRLHGRRLHCPSEQ
LQQPGREHLQAPREYRPCR*GDHVPNFSNLNAP
YAKPFFLFGQYERQRWYRKVGKYF*RKVPEPTP
GY*FPLCSKRTQSSCSPCQHLGHCS*FQKTIIVY
RHLCLCYG*APL*YRPSGQFREHPWAGRAKLFN
SSTFHSPFK*CLCNTCTHRQTSKPEH*F*GHHL
HGH*IFFFRLHPPPRMPKPLGLRASDVPHH*AFQ
K*PLPSHHTLSSRRGSHCEIS*LYVFPLKELLC
QLWGACKNSRIHKYYRLY*HKVCQCPSSNCGQS
CLPWRSWRQSGGLNLLPSRARSRTESPQL*Q*GE
*GQRPQSHHCNILPGG**LRENPVQQHHCSQDR
ARQQLLGRGAKCAICTHQEELLHQ*QTRQAAEH
SKPAKSLPEKQVLQAGGPRGQPVHEETVQNIGFP
KL*KQAQLNLLNIRHRRLKNPALKFSPTPVFPL
SLNHTCFILS*AKQAMLWEVLTQR*LLGHRSRK
HLI*PSARHRGFKACSHLLGREGEEREKEGLEMN
VYPQSQQKAMRAGETRGFEHAPCQEASVDF*PL
SRVVGCRAKLQNKIK*PAYTMRYSKLPFCFLFT
LAPSLVTDEEHPLYSV*AGSKQFYLTSHILLMPT
LL*LIIIKKKQGNSHSSPVSYLFTSGATTVYPF
LKKIREQKCLFVLQSK*KKS*C*KNKSQVIYYI
QWAFKSSRASSGECN*IILYFLIYFVSHLSWMNS
FTEYVILNLKKKKKK

Frame 1

AAAK*KQQELLRGLLLPVPRISAQAQKSWIERA
FYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTP
SISVLQNEKNESRLSRNDIQSEKWSISKHTQLSP
TDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLL
HLMTKEWQLELPKLLISVHGGLQNFELQPKLKQ
VFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDAL
KDHASKSRGKICTIGIAPWGIVENQEDLIGRDV
VRPYQTMSNPMSKLTVLNSMHSHFILADNGTTG
KYGAEVKLRRQLEKHISLQKINTRIGQGVPVVAL
IVEGGPNVISIVLEYLRDTPPVPVVVCDGSGRA
SDILAFGHKYSEEGGLINESLRDQLLVTIQKTF
TYTRTQAQHLFIILMECMKKKELITVFRMGSEGH
QDIDLAILTALLKGANASAPDQLSLALAWNRVD
IARSQIFIYGQQWPVGSLEQAMLDALVLDRVDF
VKLLIENGVSMHRFLTISRLEELYNTRHGPSNTL
YHLVRDVKKREYPGFGWIYFKGNLPPDYRISLI
DIGLVIEYLMGGAYRCNYTRKRFRTLYHNLFGP
KRDDIPLRRGRKTTKKREEEVDIDLDDPEINHFP
FPFHELMVWAVLMKRQKMALFFWQHGEEAMAKA
LVACKLCKAMAHEASENDMVDDISQELNHNSRD
FGQLAVELLDQSYKQDEQLAMKLLTYELKNWSNA
TCLQLAVAAKHRDFIAHTCSQMLLTDMWMGRLR
MRKNSGLKVILGILLPPSILSLEFKNKDDMPYM
SQAQEIHLQEKEAEEPEKPTKEKEEEDMELTAML
GRNNGESSRKKDEEEVQSKHRLIPLGRKIYEFY
NAPIVKFWFYTLAYIGYLMLFNYIVLVKMERWP
STQEWIVISYIFTLGIEKMREILMSEPGKLLQKV
KVWLQEYWNVTDLIAILLFSVGMILRLQDQPFR
SDGRVIYCVNIIYWYIRLLDIFGVNKYLGPYVM
MIGKMMIDMMYFVIIMLVVLMSFGVARQAILFPN
EEPSWKLAKNIFYMPYWMIYGEVFADQIDPPCG
QNETREDGKIIQLPPCKTGAWIVPAIMACYLLV
ANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQ
LIMTFHERPVLPPPLIIFSHMTMIFQHLCCRWR
KHESDPDERDYGLKLFITDDELKKVHDFEEQCI
EEYFREKDDRFNSSNDERIRVTSERVENMSMRLE
EVNEREHSMKASLQTVDIRLAQLEDLIGRMATA
LERLTGLERAESNKIRSRTSSDCTDAAYIVRQS
SFNSQEGNTFKLQESIDPAGEETMSPTSPTLMPR
MRSHSFYSVNMKDKGGIEKLESIFKERSLSLHR
ATSSHSVAKEPKAPAAPANTLAIVPDSRRPSSC
IDIYVSAMDELHCDIDPLDNSVNILGLGEPSFST
PVPSTAPSSSAYATLAPTDRPPSRSIDFEDITS
MDTRSFSSDYTHLPECQNPWDSEPPMYHTIERS
KSSRYLATTPFLLEEAPIVKSHSFMFSPSRSYYA
NFGVPVKTAEYTSITDCIDTRCVNAPQAIADRA
AFPGGLGDKVEDLTCCHPEREAELSHPSSDSEE
NEAKGRRATIAISSQEGDNSERTLSNNITVPKIE
RANSYSAEEPSAPYAHTRKSFSISDKLDRQRNT
ASLRNPFQRSKSSKPEGRGDSLSMRRLSRTSAF
QSFESKHN*TFLISATEGSRIQP*NSLQLQFFPF
P*IIPALFLAEQNKQCFGRC*LKGDFWATDQES
I*SDPVPDTGDLRHVHTCWAGRGKRGRRKG*R*
MCIRSHSRKP*EQGKQGASSTLHARRHLLISDHY
QEL*DAGLNCKIK*NSQRTQ*DILNFHSVFFSH
WLHHW*LMKSILFIQYKPAASSST*RPTSFSCQ
HFCN*SL*RKNKVTVIVHLSLIYSLLVPQLFILF
*RK*GNRNAFLYCNRNERRVDVKKTKVK*FIIY
SGRSSLVEQAQENVIK*FYIF*FILYLTCHG*I
HSLNM*Y*T*KKKKK

Frame 2

LQQNESNRSCSGDCFCQYPESVLRLRNPG*KEH
FIKENVSTSYPAPKTPIGVAVGV**ASMLASPP
VSPCFRMRKMKVASPEMTSSLKSGPSANTLNSA
LRMLLGPLSSKEVAIPTKPCMCEYLLIQNLISSY
T**PRNGSWSFPSFSSLSMGACRTLNSSQNSSK
SLGKGSSKQQ*QLERGYSLEGLTQVLFVMLAMP
*RIMPLSLEERYAP*VLPPGELWKTRRTSLEEML
SGHTRPCPIP*ASSLFSTACIPTSFWLTTGPLE
NMEQR*NFEDNWKSIFHSRR*TQESVKVFLWWH
S*WKEDPM*SRLFWSTFETPLPCQWLSVMGVDGH
RTSWPLGINTQKKAD**MNL*GTSCW*LYRRLS
HTLEPKLSICSSSSWSA*RRRN*LRYFGWDQKD
TRTLIWLS*QLYSKEPMPRPQTN*A*L*PGTEST
SLAARSLFTGNSGRWDLWSKPCWMP*FWTEWIL
*NYS*RME*ACTVFSPSPD*RNCTIRDMGPQIH
CTTWSGMSKSESIQVSVGSILRGTCPQTTESA*L
TSAW*SST*WAGLIAATTRASASGPSTTTSSAP
RGMIFP*GEEERQPRNVKKRWTLTWMILRSTTS
PSLSMSSWCGLFS*SGRRWPCSSGSTVRRPWPRP
WWPASSAKPWLMRPLRTTWLTTFPRS*ITIPET
LASWLWSSWTSPTSRTNSWP*NC*RMS*RTGAT
PRACSLPWLPNTATSSRTRAARCCSPTCGWAGSA
CARTQASR*FWEFYFLLQFSAWSSRTKTTCPIC
LRPRKSTSKRRRQKNQRSPQRKKRKRTWSSQQC
WDETTGSPPGRRMKRKFRASTG*SPSAEKSMNST
MHPS*SSGSTHWRISDT*CSSTISC**RWNAGR
PPRNGS*SPIFSPWE*KR*ERF*CQSQGSCYRK
*RYGCRSTGMSRTSSPSFCFLSE*SFVSKTSPSG
VTGGSSTA*TSFTGISVS*TSSA*TSIWARM**
*LEK***T*CTLSSLCWWF**ALGSPGKPSFFP
MRSHHGNWPRTSSTCPIG*FMGKCLRTR*TLPVD
RMRPERMVK*SSCLPARQELGSCRPSWPATS*W
QTSCWSTSSLLSLTIHFLK*NRYPTKSGSFRGI
SSS*LSMKGQFCPHH*SSSAT*P*YSSTCAADGG
NTRATRMKGTTA*NSS*PMMSSRKYMTLKSNA*
KNTSEKRMIGSTHLMMRGYG*LQKGWRTCLCGW
RKSTRESTP*RLHSRPWTSGWRSWKTLSGAWPRP
WSA*QVWSGPSPTKSARGPRQTARTPPTLSVRA
ASTARKGTPSSSKRV*TLQVRRPCPQLLQP*CP
VCEAILSIRSI*KTKVV*KSWKVFLKKGP*AYTG
LLVPTL*QKNPKLLQPLPTPWPLFLIPEDHHRV
*TSMSLLWMSSTVI*TLWTIP*TSLGWASQAFQ
LQYLPQPLQVVPMQHLHPQTDLQAGALILRTSPP
WTLDLFLQTTPTSQNAKTPGTQSLRCTTPLSVP
KVAAT*PPHPFF*KRLPL*NLIALCFPPQGAIM
PTLGCL*KQQNTQVLQTVLTQGVSMPLKQLRTEL
PSLEVLETKWRT*LAAIQSEKQN*VTPALTVRR
MRPKAAEPPLQYPPRRVITQREPCPTTSLFPR*
SAPTATRQRSQVRHMHTPGRASPSVTNSTGSGTQ
QACEIPSREASPPSRRAEGTACP*GDCPEHRLS
KALKASTTKPS*YPPQKAQESSPKILSNSSFSP
FLESYLLYS*LSKTSNALGGVNSKVTSGPQIKKA
FDLTQCQTQGI*GMFTLAGQGGGREGEGRVRDE
CVSAVTAESHESRGNKGLRARSMPGGIC*FLTI
IKSCRMQG*IAK*NKIASVHNEIF*TSILFSFHI
GSITGD**RASSLFSISRQQAVLPNVPHPSHAN
TSVIDHYKEKTR*QS*FTCLLSIHFWCHNCLSF
FEENKGTEMPFCIAIEMKEELMLKKQKSSDLLYT
VGVQV*SSKLRRM*LNNFIFFNLFCISPVMDEF
IH*ICNIELKKKKKK

Sequence NM_206946

AGCTGCAGCAAAATGAAAGCAACAGGAGCTGCTCCGGGGACTGCTTTTGCCAGTACCCAGAATCAGTGCTCAGGCTCAGAAATCCTGGATAGAAAGAGCA
TTTTATAAAAGAGAATGTGTCCACATCATACCCAGCACCAAAGACCCCCATAGGTGTTGCTGTGGGCGTCTGATAGGCCAGCATGTTGGCCTCACCCCCA
GTATCTCCGTGCTTCAGAATGAGAAAAATGAAAGTCGCCTCTCCCGAAATGACATCCAGTCTGAAAAGTGGTCCATCAGCAAACACACTCAACTCAGCCC
TACGGATGCTTTTGGGACCATTGAGTTCCAAGGAGGTGGCCATTCCAACAAAGCCATGTATGTGCGAGTATCTTTTGATACAAAACCTGATCTCCTCTTA
CACCTGATGACCAAGGAATGGCAGTTGGAGCTTCCCAAGCTTCTCATCTCTGTCCATGGGGGCCTGCAGAACTTTGAACTCCAGCCAAAACTCAAGCAAG
TCTTTGGGAAAGGGCTCATCAAAGCAGCAATGACAACTGGAGCGTGGATATTCACTGGAGGGGTTAACACAGGTGTTATTCGTCATGTTGGCGATGCCTT
GAAGGATCATGCCTCTAAGTCTCGAGGAAAGATATGCACCATAGGTATTGCCCCCTGGGGAATTGTGGAAAACCAGGAGGACCTCATTGGAAGAGATGTT
GTCCGGCCATACCAGACCATGTCCAATCCCATGAGCAAGCTCACTGTTCTCAACAGCATGCATTCCCACTTCATTCTGGCTGACAACGGGACCACTGGAA
AATATGGAGCAGAGGTGAAACTTCGAAGACAACTGGAAAAGCATATTTCACTCCAGAAGATAAACACAAGATGCCTGCCGTTTTTCTCTCTTGACTCCCG
CTTGTTTTATTCATTTTGGGGTAGTTGCCAGTTAGACTCAGTTGGAATCGGTCAAGGTGTTCCTGTGGTGGCACTCATAGTGGAAGGAGGACCCAATGTG
ATCTCGATTGTTTTGGAGTACCTTCGAGACACCCCTCCCGTGCCAGTGGTTGTCTGTGATGGGAGTGGACGGGCATCGGACATCCTGGCCTTTGGGCATA
AATACTCAGAAGAAGGCGGACTGATAAATGAATCTTTGAGGGACCAGCTGTTGGTGACTATACAGAAGACTTTCACATACACTCGAACCCAAGCTCAGCA
TCTGTTCATCATCCTCATGGAGTGCATGAAGAAGAAGGAATTGATTACGGTATTTCGGATGGGATCAGAAGGACACCAGGACATTGATTTGGCTATCCTG
ACAGCTTTACTCAAAGGAGCCAATGCCTCGGCCCCAGACCAACTGAGCTTAGCTTTAGCCTGGAACAGAGTCGACATCGCTCGCAGCCAGATCTTTATTT
ACGGGCAACAGTGGCCGGTGGGATCTCTGGAGCAAGCCATGTTGGATGCCTTAGTTCTGGACAGAGTGGATTTTGTGAAATTACTCATAGAGAATGGAGT
AAGCATGCACCGTTTTCTCACCATCTCCAGACTAGAGGAATTGTACAATACGAGACATGGGCCCTCAAATACATTGTACCACTTGGTCAGGGATGTCAAA
AAGGGGAACCTGCCCCCAGACTACAGAATCAGCCTGATTGACATCGGCCTGGTGATCGAGTACCTGATGGGCGGGGCTTATCGCTGCAACTACACGCGCA
AGCGCTTCCGGACCCTCTACCACAACCTCTTCGGCCCCAAGAGGCCCAAAGCCTTGAAACTGCTGGGAATGGAGGATGATATTCCCTTGAGGCGAGGAAG
AAAGACAACCAAGAAACGTGAAGAAGAGGTGGACATTGACTTGGATGATCCTGAGATCAACCACTTCCCCTTCCCTTTCCATGAGCTCATGGTGTGGGCT
GTTCTCATGAAGCGGCAGAAGATGGCCCTGTTCTTCTGGCAGCACGGTGAGGAGGCCATGGCCAAGGCCCTGGTGGCCTGCAAGCTCTGCAAAGCCATGG
CTCATGAGGCCTCTGAGAACGACATGGTTGACGACATTTCCCAGGAGCTGAATCACAATTCCAGAGACTTTGGCCAGCTGGCTGTGGAGCTCCTGGACCA
GTCCTACAAGCAGGACGAACAGCTGGCCATGAAACTGCTGACGTATGAGCTGAAGAACTGGAGCAACGCCACGTGCCTGCAGCTTGCCGTGGCTGCCAAA
CACCGCGACTTCATCGCGCACACGTGCAGCCAGATGCTGCTCACCGACATGTGGATGGGCCGGCTCCGCATGCGCAAGAACTCAGGCCTCAAGGTAATTC
TGGGAATTCTACTTCCTCCTTCAATTCTCAGCTTGGAGTTCAAGAACAAAGACGACATGCCCTATATGTCTCAGGCCCAGGAAATCCACCTCCAAGAGAA
GGAGGCAGAAGAACCAGAGAAGCCCACAAAGGAAAAAGAGGAAGAGGACATGGAGCTCACAGCAATGTTGGGACGAAACAACGGGGAGTCCTCCAGGAAG
AAGGATGAAGAGGAAGTTCAGAGCAAGCACCGGTTAATCCCCCTCGGCAGAAAAATCTATGAATTCTACAATGCACCCATCGTGAAGTTCTGGTTCTACA
CACTGGCGTATATCGGATACCTGATGCTCTTCAACTATATCGTGTTAGTGAAGATGGAACGCTGGCCGTCCACCCAGGAATGGATCGTAATCTCCTATAT
TTTCACCCTGGGAATAGAAAAGATGAGAGAGATTCTGATGTCAGAGCCAGGGAAGTTGCTACAGAAAGTGAAGGTATGGCTGCAGGAGTACTGGAATGTC
ACGGACCTCATCGCCATCCTTCTGTTTTCTGTCGGAATGATCCTTCGTCTCCAAGACCAGCCCTTCAGGAGTGACGGGAGGGTCATCTACTGCGTGAACA
TCATTTACTGGTATATCCGTCTCCTAGACATCTTCGGCGTGAACAAGTATTTGGGCCCGTATGTAATGATGATTGGAAAAATGATGATAGACATGATGTA
CTTTGTCATCATTATGCTGGTGGTTCTGATGAGCTTTGGGGTCGCCAGGCAAGCCATCCTTTTTCCCAATGAGGAGCCATCATGGAAACTGGCCAAGAAC
ATCTTCTACATGCCCTATTGGATGATTTATGGGGAAGTGTTTGCGGACCAGATAGACCCTCCCTGTGGACAGAATGAGACCCGAGAGGATGGTAAAATAA
TCCAGCTGCCTCCCTGCAAGACAGGAGCTTGGATCGTGCCGGCCATCATGGCCTGCTACCTCTTAGTGGCAAACATCTTGCTGGTCAACCTCCTCATTGC
TGTCTTTAACAATACATTTTTTGAAGTAAAATCGATATCCAACCAAGTCTGGAAGTTTCAGAGGTATCAGCTCATCATGACTTTCCATGAAAGGCCAGTT
CTGCCCCCACCACTGATCATCTTCAGCCACATGACCATGATATTCCAGCACCTGTGCTGCCGATGGAGGAAACACGAGAGCGACCCGGATGAAAGGGACT
ACGGCCTGAAACTCTTCATAACCGATGATGAGCTCAAGAAAGTACATGACTTTGAAGAGCAATGCATAGAAGAATACTTCAGAGAAAAGGATGATCGGTT
CAACTCATCTAATGATGAGAGGATACGGGTGACTTCAGAAAGGGTGGAGAACATGTCTATGCGGCTGGAGGAAGTCAACGAGAGAGAGCACTCCATGAAG
GCTTCACTCCAGACCGTGGACATCCGGCTGGCGCAGCTGGAAGACCTTATCGGGCGCATGGCCACGGCCCTGGAGCGCCTGACAGGTCTGGAGCGGGCCG
AGTCCAACAAAATCCGCTCGAGGACCTCGTCAGACTGCACGGACGCCGCCTACATTGTCCGTCAGAGCAGCTTCAACAGCCAGGAAGGGAACACCTTCAA
GCTCCAAGAGAGTATAGACCCTGCAGGTGAGGAGACCATGTCCCCAACTTCTCCAACCTTAATGCCCCGTATGCGAAGCCATTCTTTCTATTCGGTCAAT
ATGAAAGACAAAGGTGGTATAGAAAAGTTGGAAAGTATTTTTAAAGAAAGGTCCCTGAGCCTACACCGGGCTACTAGTTCCCACTCTGTAGCAAAAGAAC
CCAAAGCTCCTGCAGCCCCTGCCAACACCTTGGCCATTGTTCCTGATTCCAGAAGACCATCATCGTGTATAGACATCTATGTCTCTGCTATGGATGAGCT
CCACTGTGATATAGACCCTCTGGACAATTCCGTGAACATCCTTGGGCTGGGCGAGCCAAGCTTTTCAACTCCAGTACCTTCCACAGCCCCTTCAAGTAGT
GCCTATGCAACACTTGCACCCACAGACAGACCTCCAAGCCGGAGCATTGATTTTGAGGACATCACCTCCATGGACACTAGATCTTTTTCTTCAGACTACA
CCCACCTCCCAGAATGCCAAAACCCCTGGGACTCAGAGCCTCCGATGTACCACACCATTGAGCGTTCCAAAAGTAGCCGCTACCTAGCCACCACACCCTT
TCTTCTAGAAGAGGCTCCCATTGTGAAATCTCATAGCTTTATGTTTTCCCCCTCAAGGAGCTATTATGCCAACTTTGGGGTGCCTGTAAAAACAGCAGAA
TACACAAGTATTACAGACTGTATTGACACAAGGTGTGTCAATGCCCCTCAAGCAATTGCGGACAGAGCTGCCTTCCCTGGAGGTCTTGGAGACAAAGTGG
AGGACTTAACTTGCTGCCATCCAGAGCGAGAAGCAGAACTGAGTCACCCCAGCTCTGACAGTGAGGAGAATGAGGCCAAAGGCCGCAGAGCCACCATTGC
AATATCCTCCCAGGAGGGTGATAACTCAGAGAGAACCCTGTCCAACAACATCACTGTTCCCAAGATAGAGCGCGCCAACAGCTACTCGGCAGAGGAGCCA
AGTGCGCCATATGCACACACCAGGAAGAGCTTCTCCATCAGTGACAAACTCGACAGGCAGCGGAACACAGCAAGCCTGCGAAATCCCTTCCAGAGAAGCA
AGTCCTCCAAGCCGGAGGGCCGAGGGGACAGCCTGTCCATGAGGAGACTGTCCAGAACATCGGCTTTCCAAAGCTTTGAAAGCAAGCACAACTAAACCTT
CTTAATATCCGCCACAGAAGGCTCAAGAATCCAGCCCTAAAATTCTCTCCAACTCCAGTTTTTCCCCTTTCCTTGAATCATACCTGCTTTATTCTTAGCT
GAGCAAAACAAGCAATGCTTTGGGAGGTGTTAACTCAAAGGTGACTTCTGGGCCACAGATCAAGAAAGCATTTGATCTGACCCAGTGCCAGACACAGGGG
ATTTAAGGCATGTTCACACTTGCTGGGCAGGGAGGGGGAAGAGAGGGAGAAGGAAGGGTTAGAGATGAATGTGTATCCGCAGTCACAGCAGAAAGCCATG
AGAGCAGGGGAAACAAGGGGCTTCGAGCACGCTCCATGCCAGGAGGCATCTGTTGATTTCTGACCATTATCAAGAGTTGTAGGATGCAGGGCTAAATTGC
AAAATAAAATAAAATAGCCAGCGTACACAATGAGATATTCTAAACTTCCATTCTGTTTTCTTTTCACATTGGCTCCATCACTGGTGACTGATGAAGAGCA
TCCTCTTTATTCAGTATAAGCCGGCAGCAAGCAGTTCTACCTAACGTCCCACATCCTTCTCATGCCAACACTTCTGTAATTGATCATTATAAAGAAAAAA
CAAGGTAACAGTCATAGTTCACCTGTCTCTTATCTATTCACTTCTGGTGCCACAACTGTTTATCCTTTTTTGAAGAAAATAAGGGAACAGAAATGCCTTT
TTGTATTGCAATCGAAATGAAAGAAGAGTTGATGTTAAAAAAACAAAAGTCAAGTGATTTATTATATACAGTGGGCGTTCAAGTCTAGTCGAGCAAGCTC
AGGAGAATGTAATTAAATAATTTTATATTTTTTAATTTATTTTGTATCTCACCTGTCATGGATGAATTCATTCACTGAATATGTAATATTGAACTTAAAA
AAAAAAAAAAAAAAA
  • refseq_TRPM3.F6 (forward primer)
  • refseq_TRPM3.R6 (reverse primer)
  • Single exon skipping

Frame 0

SCSKMKATGAAPGTAFASTQNQCSGSEILDRKS
IL*KRMCPHHTQHQRPP*VLLWASDRPACWPHPQ
YLRASE*EK*KSPLPK*HPV*KVVHQQTHSTQP
YGCFWDH*VPRRWPFQQSHVCASIF*YKT*SPL
TPDDQGMAVGASQASHLCPWGPAEL*TPAKTQAS
LWERAHQSSNDNWSVDIHWRG*HRCYSSCWRCL
EGSCL*VSRKDMHHRYCPLGNCGKPGGPHWKRC
CPAIPDHVQSHEQAHCSQQHAFPLHSG*QRDHWK
IWSRGETSKTTGKAYFTPEDKHKMPAVFLS*LP
LVLFILG*LPVRLSWNRSRCSCGGTHSGRRTQC
DLDCFGVPSRHPSRASGCL*WEWTGIGHPGLWA*
ILRRRRTDK*IFEGPAVGDYTEDFHIHSNPSSA
SVHHPHGVHEEEGIDYGISDGIRRTPGH*FGYP
DSFTQRSQCLGPRPTELSFSLEQSRHRSQPDLYL
RATVAGGISGASHVGCLSSGQSGFCEITHREWS
KHAPFSHHLQTRGIVQYETWALKYIVPLGQGCQ
KGEPAPRLQNQPD*HRPGDRVPDGRGLSLQLHAQ
ALPDPLPQPLRPQEAQSLETAGNGG*YSLEARK
KDNQET*RRGGH*LG*S*DQPLPLPFP*AHGVG
CSHEAAEDGPVLLAAR*GGHGQGPGGLQALQSHG
S*GL*ERHG*RHFPGAESQFQRLWPAGCGAPGP
VLQAGRTAGHETADV*AEELEQRHVPAACRGCQ
TPRLHRAHVQPDAAHRHVDGPAPHAQELRPQGNS
GNSTSSFNSQLGVQEQRRHALYVSGPGNPPPRE
GGRRTREAHKGKRGRGHGAHSNVGTKQRGVLQE
EG*RGSSEQAPVNPPRQKNL*ILQCTHREVLVLH
TGVYRIPDALQLYRVSEDGTLAVHPGMDRNLLY
FHPGNRKDERDSDVRAREVATESEGMAAGVLEC
HGPHRHPSVFCRNDPSSPRPALQE*REGHLLREH
HLLVYPSPRHLRREQVFGPVCNDDWKNDDRHDV
LCHHYAGGSDELWGRQASHPFSQ*GAIMETGQE
HLLHALLDDLWGSVCGPDRPSLWTE*DPRGW*NN
PAASLQDRSLDRAGHHGLLPLSGKHLAGQPPHC
CL*QYIF*SKIDIQPSLEVSEVSAHHDFP*KAS
SAPTTDHLQPHDHDIPAPVLPMEETRERPG*KGL
RPETLHNR**AQEST*L*RAMHRRILQRKG*SV
QLI***EDTGDFRKGGEHVYAAGGSQRERALHE
GFTPDRGHPAGAAGRPYRAHGHGPGAPDRSGAGR
VQQNPLEDLVRLHGRRLHCPSEQLQQPGREHLQ
APREYRPCR*GDHVPNFSNLNAPYAKPFFLFGQ
YERQRWYRKVGKYF*RKVPEPTPGY*FPLCSKRT
QSSCSPCQHLGHCS*FQKTIIVYRHLCLCYG*A
PL*YRPSGQFREHPWAGRAKLFNSSTFHSPFK*
CLCNTCTHRQTSKPEH*F*GHHLHGH*IFFFRLH
PPPRMPKPLGLRASDVPHH*AFQK*PLPSHHTL
SSRRGSHCEIS*LYVFPLKELLCQLWGACKNSR
IHKYYRLY*HKVCQCPSSNCGQSCLPWRSWRQSG
GLNLLPSRARSRTESPQL*Q*GE*GQRPQSHHC
NILPGG**LRENPVQQHHCSQDRARQQLLGRGA
KCAICTHQEELLHQ*QTRQAAEHSKPAKSLPEKQ
VLQAGGPRGQPVHEETVQNIGFPKL*KQAQLNL
LNIRHRRLKNPALKFSPTPVFPLSLNHTCFILS
*AKQAMLWEVLTQR*LLGHRSRKHLI*PSARHRG
FKACSHLLGREGEEREKEGLEMNVYPQSQQKAM
RAGETRGFEHAPCQEASVDF*PLSRVVGCRAKL
QNKIK*PAYTMRYSKLPFCFLFTLAPSLVTDEEH
PLYSV*AGSKQFYLTSHILLMPTLL*LIIIKKK
QGNSHSSPVSYLFTSGATTVYPFLKKIREQKCL
FVLQSK*KKS*C*KNKSQVIYYIQWAFKSSRASS
GECN*IILYFLIYFVSHLSWMNSFTEYVILNLK
KKKKK

Frame 1

AAAK*KQQELLRGLLLPVPRISAQAQKSWIERA
FYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTP
SISVLQNEKNESRLSRNDIQSEKWSISKHTQLSP
TDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLL
HLMTKEWQLELPKLLISVHGGLQNFELQPKLKQ
VFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDAL
KDHASKSRGKICTIGIAPWGIVENQEDLIGRDV
VRPYQTMSNPMSKLTVLNSMHSHFILADNGTTG
KYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSR
LFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNV
ISIVLEYLRDTPPVPVVVCDGSGRASDILAFGH
KYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQH
LFIILMECMKKKELITVFRMGSEGHQDIDLAIL
TALLKGANASAPDQLSLALAWNRVDIARSQIFI
YGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGV
SMHRFLTISRLEELYNTRHGPSNTLYHLVRDVK
KGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTR
KRFRTLYHNLFGPKRPKALKLLGMEDDIPLRRGR
KTTKKREEEVDIDLDDPEINHFPFPFHELMVWA
VLMKRQKMALFFWQHGEEAMAKALVACKLCKAM
AHEASENDMVDDISQELNHNSRDFGQLAVELLDQ
SYKQDEQLAMKLLTYELKNWSNATCLQLAVAAK
HRDFIAHTCSQMLLTDMWMGRLRMRKNSGLKVI
LGILLPPSILSLEFKNKDDMPYMSQAQEIHLQEK
EAEEPEKPTKEKEEEDMELTAMLGRNNGESSRK
KDEEEVQSKHRLIPLGRKIYEFYNAPIVKFWFY
TLAYIGYLMLFNYIVLVKMERWPSTQEWIVISYI
FTLGIEKMREILMSEPGKLLQKVKVWLQEYWNV
TDLIAILLFSVGMILRLQDQPFRSDGRVIYCVN
IIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMY
FVIIMLVVLMSFGVARQAILFPNEEPSWKLAKN
IFYMPYWMIYGEVFADQIDPPCGQNETREDGKI
IQLPPCKTGAWIVPAIMACYLLVANILLVNLLIA
VFNNTFFEVKSISNQVWKFQRYQLIMTFHERPV
LPPPLIIFSHMTMIFQHLCCRWRKHESDPDERD
YGLKLFITDDELKKVHDFEEQCIEEYFREKDDRF
NSSNDERIRVTSERVENMSMRLEEVNEREHSMK
ASLQTVDIRLAQLEDLIGRMATALERLTGLERA
ESNKIRSRTSSDCTDAAYIVRQSSFNSQEGNTFK
LQESIDPAGEETMSPTSPTLMPRMRSHSFYSVN
MKDKGGIEKLESIFKERSLSLHRATSSHSVAKE
PKAPAAPANTLAIVPDSRRPSSCIDIYVSAMDEL
HCDIDPLDNSVNILGLGEPSFSTPVPSTAPSSS
AYATLAPTDRPPSRSIDFEDITSMDTRSFSSDY
THLPECQNPWDSEPPMYHTIERSKSSRYLATTPF
LLEEAPIVKSHSFMFSPSRSYYANFGVPVKTAE
YTSITDCIDTRCVNAPQAIADRAAFPGGLGDKV
EDLTCCHPEREAELSHPSSDSEENEAKGRRATIA
ISSQEGDNSERTLSNNITVPKIERANSYSAEEP
SAPYAHTRKSFSISDKLDRQRNTASLRNPFQRS
KSSKPEGRGDSLSMRRLSRTSAFQSFESKHN*TF
LISATEGSRIQP*NSLQLQFFPFP*IIPALFLA
EQNKQCFGRC*LKGDFWATDQESI*SDPVPDTG
DLRHVHTCWAGRGKRGRRKG*R*MCIRSHSRKP*
EQGKQGASSTLHARRHLLISDHYQEL*DAGLNC
KIK*NSQRTQ*DILNFHSVFFSHWLHHW*LMKS
ILFIQYKPAASSST*RPTSFSCQHFCN*SL*RKN
KVTVIVHLSLIYSLLVPQLFILF*RK*GNRNAF
LYCNRNERRVDVKKTKVK*FIIYSGRSSLVEQA
QENVIK*FYIF*FILYLTCHG*IHSLNM*Y*T*K
KKKK

Frame 2

LQQNESNRSCSGDCFCQYPESVLRLRNPG*KEH
FIKENVSTSYPAPKTPIGVAVGV**ASMLASPP
VSPCFRMRKMKVASPEMTSSLKSGPSANTLNSA
LRMLLGPLSSKEVAIPTKPCMCEYLLIQNLISSY
T**PRNGSWSFPSFSSLSMGACRTLNSSQNSSK
SLGKGSSKQQ*QLERGYSLEGLTQVLFVMLAMP
*RIMPLSLEERYAP*VLPPGELWKTRRTSLEEML
SGHTRPCPIP*ASSLFSTACIPTSFWLTTGPLE
NMEQR*NFEDNWKSIFHSRR*TQDACRFSLLTP
ACFIHFGVVAS*TQLESVKVFLWWHS*WKEDPM*
SRLFWSTFETPLPCQWLSVMGVDGHRTSWPLGI
NTQKKAD**MNL*GTSCW*LYRRLSHTLEPKLS
ICSSSSWSA*RRRN*LRYFGWDQKDTRTLIWLS*
QLYSKEPMPRPQTN*A*L*PGTESTSLAARSLF
TGNSGRWDLWSKPCWMP*FWTEWIL*NYS*RME
*ACTVFSPSPD*RNCTIRDMGPQIHCTTWSGMSK
RGTCPQTTESA*LTSAW*SST*WAGLIAATTRA
SASGPSTTTSSAPRGPKP*NCWEWRMIFP*GEE
ERQPRNVKKRWTLTWMILRSTTSPSLSMSSWCGL
FS*SGRRWPCSSGSTVRRPWPRPWWPASSAKPW
LMRPLRTTWLTTFPRS*ITIPETLASWLWSSWT
SPTSRTNSWP*NC*RMS*RTGATPRACSLPWLPN
TATSSRTRAARCCSPTCGWAGSACARTQASR*F
WEFYFLLQFSAWSSRTKTTCPICLRPRKSTSKR
RRQKNQRSPQRKKRKRTWSSQQCWDETTGSPPGR
RMKRKFRASTG*SPSAEKSMNSTMHPS*SSGST
HWRISDT*CSSTISC**RWNAGRPPRNGS*SPI
FSPWE*KR*ERF*CQSQGSCYRK*RYGCRSTGMS
RTSSPSFCFLSE*SFVSKTSPSGVTGGSSTA*T
SFTGISVS*TSSA*TSIWARM***LEK***T*C
TLSSLCWWF**ALGSPGKPSFFPMRSHHGNWPRT
SSTCPIG*FMGKCLRTR*TLPVDRMRPERMVK*
SSCLPARQELGSCRPSWPATS*WQTSCWSTSSL
LSLTIHFLK*NRYPTKSGSFRGISSS*LSMKGQF
CPHH*SSSAT*P*YSSTCAADGGNTRATRMKGT
TA*NSS*PMMSSRKYMTLKSNA*KNTSEKRMIG
STHLMMRGYG*LQKGWRTCLCGWRKSTRESTP*R
LHSRPWTSGWRSWKTLSGAWPRPWSA*QVWSGP
SPTKSARGPRQTARTPPTLSVRAASTARKGTPS
SSKRV*TLQVRRPCPQLLQP*CPVCEAILSIRSI
*KTKVV*KSWKVFLKKGP*AYTGLLVPTL*QKN
PKLLQPLPTPWPLFLIPEDHHRV*TSMSLLWMS
STVI*TLWTIP*TSLGWASQAFQLQYLPQPLQVV
PMQHLHPQTDLQAGALILRTSPPWTLDLFLQTT
PTSQNAKTPGTQSLRCTTPLSVPKVAAT*PPHP
FF*KRLPL*NLIALCFPPQGAIMPTLGCL*KQQN
TQVLQTVLTQGVSMPLKQLRTELPSLEVLETKW
RT*LAAIQSEKQN*VTPALTVRRMRPKAAEPPL
QYPPRRVITQREPCPTTSLFPR*SAPTATRQRSQ
VRHMHTPGRASPSVTNSTGSGTQQACEIPSREA
SPPSRRAEGTACP*GDCPEHRLSKALKASTTKP
S*YPPQKAQESSPKILSNSSFSPFLESYLLYS*L
SKTSNALGGVNSKVTSGPQIKKAFDLTQCQTQG
I*GMFTLAGQGGGREGEGRVRDECVSAVTAESH
ESRGNKGLRARSMPGGIC*FLTIIKSCRMQG*IA
K*NKIASVHNEIF*TSILFSFHIGSITGD**RA
SSLFSISRQQAVLPNVPHPSHANTSVIDHYKEK
TR*QS*FTCLLSIHFWCHNCLSFFEENKGTEMPF
CIAIEMKEELMLKKQKSSDLLYTVGVQV*SSKL
RRM*LNNFIFFNLFCISPVMDEFIH*ICNIELK
KKKKK

Sequence NM_001007470

AGCTGCAGCAAAATGAAAGCAACAGGAGCTGCTCCGGGGACTGCTTTTGCCAGTACCCAGAATCAGTGCTCAGGCTCAGAAATCCTGGATAGAAAGAGCA
TTTTATAAAAGAGAATGTGTCCACATCATACCCAGCACCAAAGACCCCCATAGGTGTTGCTGTGGGCGTCTGATAGGCCAGCATGTTGGCCTCACCCCCA
GTATCTCCGTGCTTCAGAATGAGAAAAATGAAAGTCGCCTCTCCCGAAATGACATCCAGTCTGAAAAGTGGTCCATCAGCAAACACACTCAACTCAGCCC
TACGGATGCTTTTGGGACCATTGAGTTCCAAGGAGGTGGCCATTCCAACAAAGCCATGTATGTGCGAGTATCTTTTGATACAAAACCTGATCTCCTCTTA
CACCTGATGACCAAGGAATGGCAGTTGGAGCTTCCCAAGCTTCTCATCTCTGTCCATGGGGGCCTGCAGAACTTTGAACTCCAGCCAAAACTCAAGCAAG
TCTTTGGGAAAGGGCTCATCAAAGCAGCAATGACAACTGGAGCGTGGATATTCACTGGAGGGGTTAACACAGGTGTTATTCGTCATGTTGGCGATGCCTT
GAAGGATCATGCCTCTAAGTCTCGAGGAAAGATATGCACCATAGGTATTGCCCCCTGGGGAATTGTGGAAAACCAGGAGGACCTCATTGGAAGAGATGTT
GTCCGGCCATACCAGACCATGTCCAATCCCATGAGCAAGCTCACTGTTCTCAACAGCATGCATTCCCACTTCATTCTGGCTGACAACGGGACCACTGGAA
AATATGGAGCAGAGGTGAAACTTCGAAGACAACTGGAAAAGCATATTTCACTCCAGAAGATAAACACAAGATGCCTGCCGTTTTTCTCTCTTGACTCCCG
CTTGTTTTATTCATTTTGGGGTAGTTGCCAGTTAGACTCAGTTGGAATCGGTCAAGGTGTTCCTGTGGTGGCACTCATAGTGGAAGGAGGACCCAATGTG
ATCTCGATTGTTTTGGAGTACCTTCGAGACACCCCTCCCGTGCCAGTGGTTGTCTGTGATGGGAGTGGACGGGCATCGGACATCCTGGCCTTTGGGCATA
AATACTCAGAAGAAGGCGGGTAGGTAACTTTCCAGGCCCCATGGAAGAACCCTAAAGCCTGTTTGGAAACGAGGGTATGAGTGGATTATGTTTTCAGTAG
CTCAACCAAGACCTCAAATCAAAACAAGCTATGAACAAATTGTCTAAAAAATGTCTGTCATGGGAGGGCTGTGGTGAAGAACAGAGAAACATATTCTAAA
TGTCCTGTGAAGTGGGAAATTCTATGAAAGCTACACGGATAATAAAAAGGGTGAGGAAAAGA
  • refseq_TRPM3.F6 (forward primer)
  • refseq_TRPM3.R6 (reverse primer)
  • Single exon skipping

Frame 0

SCSKMKATGAAPGTAFASTQNQCSGSEILDRKS
IL*KRMCPHHTQHQRPP*VLLWASDRPACWPHPQ
YLRASE*EK*KSPLPK*HPV*KVVHQQTHSTQP
YGCFWDH*VPRRWPFQQSHVCASIF*YKT*SPL
TPDDQGMAVGASQASHLCPWGPAEL*TPAKTQAS
LWERAHQSSNDNWSVDIHWRG*HRCYSSCWRCL
EGSCL*VSRKDMHHRYCPLGNCGKPGGPHWKRC
CPAIPDHVQSHEQAHCSQQHAFPLHSG*QRDHWK
IWSRGETSKTTGKAYFTPEDKHKMPAVFLS*LP
LVLFILG*LPVRLSWNRSRCSCGGTHSGRRTQC
DLDCFGVPSRHPSRASGCL*WEWTGIGHPGLWA*
ILRRRRVGNFPGPMEEP*SLFGNEGMSGLCFQ*
LNQDLKSKQAMNKLSKKCLSWEGCGEEQRNIF*
MSCEVGNSMKATRIIKRVRKR

Frame 1

AAAK*KQQELLRGLLLPVPRISAQAQKSWIERA
FYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTP
SISVLQNEKNESRLSRNDIQSEKWSISKHTQLSP
TDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLL
HLMTKEWQLELPKLLISVHGGLQNFELQPKLKQ
VFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDAL
KDHASKSRGKICTIGIAPWGIVENQEDLIGRDV
VRPYQTMSNPMSKLTVLNSMHSHFILADNGTTG
KYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSR
LFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNV
ISIVLEYLRDTPPVPVVVCDGSGRASDILAFGH
KYSEEGG*VTFQAPWKNPKACLETRV*VDYVFSS
STKTSNQNKL*TNCLKNVCHGRAVVKNRETYSK
CPVKWEIL*KLHG**KG*GK

Frame 2

LQQNESNRSCSGDCFCQYPESVLRLRNPG*KEH
FIKENVSTSYPAPKTPIGVAVGV**ASMLASPP
VSPCFRMRKMKVASPEMTSSLKSGPSANTLNSA
LRMLLGPLSSKEVAIPTKPCMCEYLLIQNLISSY
T**PRNGSWSFPSFSSLSMGACRTLNSSQNSSK
SLGKGSSKQQ*QLERGYSLEGLTQVLFVMLAMP
*RIMPLSLEERYAP*VLPPGELWKTRRTSLEEML
SGHTRPCPIP*ASSLFSTACIPTSFWLTTGPLE
NMEQR*NFEDNWKSIFHSRR*TQDACRFSLLTP
ACFIHFGVVAS*TQLESVKVFLWWHS*WKEDPM*
SRLFWSTFETPLPCQWLSVMGVDGHRTSWPLGI
NTQKKAGR*LSRPHGRTLKPVWKRGYEWIMFSV
AQPRPQIKTSYEQIV*KMSVMGGLW*RTEKHILN
VL*SGKFYESYTDNKKGEEK

Sequence NM_206947

AGCTGCAGCAAAATGAAAGCAACAGGAGCTGCTCCGGGGACTGCTTTTGCCAGTACCCAGAATCAGTGCTCAGGCTCAGAAATCCTGGATAGAAAGAGCA
TTTTATAAAAGAGAATGTGTCCACATCATACCCAGCACCAAAGACCCCCATAGGTGTTGCTGTGGGCGTCTGATAGGCCAGCATGTTGGCCTCACCCCCA
GTATCTCCGTGCTTCAGAATGAGAAAAATGAAAGTCGCCTCTCCCGAAATGACATCCAGTCTGAAAAGTGGTCCATCAGCAAACACACTCAACTCAGCCC
TACGGATGCTTTTGGGACCATTGAGTTCCAAGGAGGTGGCCATTCCAACAAAGCCATGTATGTGCGAGTATCTTTTGATACAAAACCTGATCTCCTCTTA
CACCTGATGACCAAGGAATGGCAGTTGGAGCTTCCCAAGCTTCTCATCTCTGTCCATGGGGGCCTGCAGAACTTTGAACTCCAGCCAAAACTCAAGCAAG
TCTTTGGGAAAGGGCTCATCAAAGCAGCAATGACAACTGGAGCGTGGATATTCACTGGAGGGGTTAACACAGGTGTTATTCGTCATGTTGGCGATGCCTT
GAAGGATCATGCCTCTAAGTCTCGAGGAAAGATATGCACCATAGGTATTGCCCCCTGGGGAATTGTGGAAAACCAGGAGGACCTCATTGGAAGAGATGTT
GTCCGGCCATACCAGACCATGTCCAATCCCATGAGCAAGCTCACTGTTCTCAACAGCATGCATTCCCACTTCATTCTGGCTGACAACGGGACCACTGGAA
AATATGGAGCAGAGGTGAAACTTCGAAGACAACTGGAAAAGCATATTTCACTCCAGAAGATAAACACAAGATGCCTGCCGTTTTTCTCTCTTGACTCCCG
CTTGTTTTATTCATTTTGGGGTAGTTGCCAGTTAGACTCAGTTGGAATCGGTCAAGGTGTTCCTGTGGTGGCACTCATAGTGGAAGGAGGACCCAATGTG
ATCTCGATTGTTTTGGAGTACCTTCGAGACACCCCTCCCGTGCCAGTGGTTGTCTGTGATGGGAGTGGACGGGCATCGGACATCCTGGCCTTTGGGCATA
AATACTCAGAAGAAGGCGGACTGATAAATGAATCTTTGAGGGACCAGCTGTTGGTGACTATACAGAAGACTTTCACATACACTCGAACCCAAGCTCAGCA
TCTGTTCATCATCCTCATGGAGTGCATGAAGAAGAAGGAATTGATTACGGTATTTCGGATGGGATCAGAAGGACACCAGGACATTGATTTGGCTATCCTG
ACAGCTTTACTCAAAGGAGCCAATGCCTCGGCCCCAGACCAACTGAGCTTAGCTTTAGCCTGGAACAGAGTCGACATCGCTCGCAGCCAGATCTTTATTT
ACGGGCAACAGTGGCCGGTGGGATCTCTGGAGCAAGCCATGTTGGATGCCTTAGTTCTGGACAGAGTGGATTTTGTGAAATTACTCATAGAGAATGGAGT
AAGCATGCACCGTTTTCTCACCATCTCCAGACTAGAGGAATTGTACAATACGAGACATGGGCCCTCAAATACATTGTACCACTTGGTCAGGGATGTCAAA
AAGGGGAACCTGCCCCCAGACTACAGAATCAGCCTGATTGACATCGGCCTGGTGATCGAGTACCTGATGGGCGGGGCTTATCGCTGCAACTACACGCGCA
AGCGCTTCCGGACCCTCTACCACAACCTCTTCGGCCCCAAGAGGGATGATATTCCCTTGAGGCGAGGAAGAAAGACAACCAAGAAACGTGAAGAAGAGGT
GGACATTGACTTGGATGATCCTGAGATCAACCACTTCCCCTTCCCTTTCCATGAGCTCATGGTGTGGGCTGTTCTCATGAAGCGGCAGAAGATGGCCCTG
TTCTTCTGGCAGCACGGTGAGGAGGCCATGGCCAAGGCCCTGGTGGCCTGCAAGCTCTGCAAAGCCATGGCTCATGAGGCCTCTGAGAACGACATGGTTG
ACGACATTTCCCAGGAGCTGAATCACAATTCCAGAGACTTTGGCCAGCTGGCTGTGGAGCTCCTGGACCAGTCCTACAAGCAGGACGAACAGCTGGCCAT
GAAACTGCTGACGTATGAGCTGAAGAACTGGAGCAACGCCACGTGCCTGCAGCTTGCCGTGGCTGCCAAACACCGCGACTTCATCGCGCACACGTGCAGC
CAGATGCTGCTCACCGACATGTGGATGGGCCGGCTCCGCATGCGCAAGAACTCAGGCCTCAAGGTAATTCTGGGAATTCTACTTCCTCCTTCAATTCTCA
GCTTGGAGTTCAAGAACAAAGACGACATGCCCTATATGTCTCAGGCCCAGGAAATCCACCTCCAAGAGAAGGAGGCAGAAGAACCAGAGAAGCCCACAAA
GGAAAAAGAGGAAGAGGACATGGAGCTCACAGCAATGTTGGGACGAAACAACGGGGAGTCCTCCAGGAAGAAGGATGAAGAGGAAGTTCAGAGCAAGCAC
CGGTTAATCCCCCTCGGCAGAAAAATCTATGAATTCTACAATGCACCCATCGTGAAGTTCTGGTTCTACACACTGGCGTATATCGGATACCTGATGCTCT
TCAACTATATCGTGTTAGTGAAGATGGAACGCTGGCCGTCCACCCAGGAATGGATCGTAATCTCCTATATTTTCACCCTGGGAATAGAAAAGATGAGAGA
GATTCTGATGTCAGAGCCAGGGAAGTTGCTACAGAAAGTGAAGGTATGGCTGCAGGAGTACTGGAATGTCACGGACCTCATCGCCATCCTTCTGTTTTCT
GTCGGAATGATCCTTCGTCTCCAAGACCAGCCCTTCAGGAGTGACGGGAGGGTCATCTACTGCGTGAACATCATTTACTGGTATATCCGTCTCCTAGACA
TCTTCGGCGTGAACAAGTATTTGGGCCCGTATGTAATGATGATTGGAAAAATGATGATAGACATGATGTACTTTGTCATCATTATGCTGGTGGTTCTGAT
GAGCTTTGGGGTCGCCAGGCAAGCCATCCTTTTTCCCAATGAGGAGCCATCATGGAAACTGGCCAAGAACATCTTCTACATGCCCTATTGGATGATTTAT
GGGGAAGTGTTTGCGGACCAGATAGACCCTCCCTGTGGACAGAATGAGACCCGAGAGGATGGTAAAATAATCCAGCTGCCTCCCTGCAAGACAGGAGCTT
GGATCGTGCCGGCCATCATGGCCTGCTACCTCTTAGTGGCAAACATCTTGCTGGTCAACCTCCTCATTGCTGTCTTTAACAATACATTTTTTGAAGTAAA
ATCGATATCCAACCAAGTCTGGAAGTTTCAGAGGTATCAGCTCATCATGACTTTCCATGAAAGGCCAGTTCTGCCCCCACCACTGATCATCTTCAGCCAC
ATGACCATGATATTCCAGCACCTGTGCTGCCGATGGAGGAAACACGAGAGCGACCCGGATGAAAGGGACTACGGCCTGAAACTCTTCATAACCGATGATG
AGCTCAAGAAAGTACATGACTTTGAAGAGCAATGCATAGAAGAATACTTCAGAGAAAAGGATGATCGGTTCAACTCATCTAATGATGAGAGGATACGGGT
GACTTCAGAAAGGGTGGAGAACATGTCTATGCGGCTGGAGGAAGTCAACGAGAGAGAGCACTCCATGAAGGCTTCACTCCAGACCGTGGACATCCGGCTG
GCGCAGCTGGAAGACCTTATCGGGCGCATGGCCACGGCCCTGGAGCGCCTGACAGGTCTGGAGCGGGCCGAGTCCAACAAAATCCGCTCGAGGACCTCGT
CAGACTGCACGGACGCCGCCTACATTGTCCGTCAGAGCAGCTTCAACAGCCAGGAAGGGAACACCTTCAAGCTCCAAGAGAGTATAGACCCTGCAGGTGA
GGAGACCATGTCCCCAACTTCTCCAACCTTAATGCCCCGTATGCGAAGCCATTCTTTCTATTCGGTCAATATGAAAGACAAAGGTGGTATAGAAAAGTTG
GAAAGTATTTTTAAAGAAAGGTCCCTGAGCCTACACCGGGCTACTAGTTCCCACTCTGTAGCAAAAGAACCCAAAGCTCCTGCAGCCCCTGCCAACACCT
TGGCCATTGTTCCTGATTCCAGAAGACCATCATCGTGTATAGACATCTATGTCTCTGCTATGGATGAGCTCCACTGTGATATAGACCCTCTGGACAATTC
CGTGAACATCCTTGGGCTGGGCGAGCCAAGCTTTTCAACTCCAGTACCTTCCACAGCCCCTTCAAGTAGTGCCTATGCAACACTTGCACCCACAGACAGA
CCTCCAAGCCGGAGCATTGATTTTGAGGACATCACCTCCATGGACACTAGATCTTTTTCTTCAGACTACACCCACCTCCCAGAATGCCAAAACCCCTGGG
ACTCAGAGCCTCCGATGTACCACACCATTGAGCGTTCCAAAAGTAGCCGCTACCTAGCCACCACACCCTTTCTTCTAGAAGAGGCTCCCATTGTGAAATC
TCATAGCTTTATGTTTTCCCCCTCAAGGAGCTATTATGCCAACTTTGGGGTGCCTGTAAAAACAGCAGAATACACAAGTATTACAGACTGTATTGACACA
AGGTGTGTCAATGCCCCTCAAGCAATTGCGGACAGAGCTGCCTTCCCTGGAGGTCTTGGAGACAAAGTGGAGGACTTAACTTGCTGCCATCCAGAGCGAG
AAGCAGAACTGAGTCACCCCAGCTCTGACAGTGAGGAGAATGAGGCCAAAGGCCGCAGAGCCACCATTGCAATATCCTCCCAGGAGGGTGATAACTCAGA
GAGAACCCTGTCCAACAACATCACTGTTCCCAAGATAGAGCGCGCCAACAGCTACTCGGCAGAGGAGCCAAGTGCGCCATATGCACACACCAGGAAGAGC
TTCTCCATCAGTGACAAACTCGACAGGCAGCGGAACACAGCAAGCCTGCGAAATCCCTTCCAGAGAAGCAAGTCCTCCAAGCCGGAGGGCCGAGGGGACA
GCCTGTCCATGAGGAGACTGTCCAGAACATCGGCTTTCCAAAGCTTTGAAAGCAAGCACAACTAAACCTTCTTAATATCCGCCACAGAAGGCTCAAGAAT
CCAGCCCTAAAATTCTCTCCAACTCCAGTTTTTCCCCTTTCCTTGAATCATACCTGCTTTATTCTTAGCTGAGCAAAACAAGCAATGCTTTGGGAGGTGT
TAACTCAAAGGTGACTTCTGGGCCACAGATCAAGAAAGCATTTGATCTGACCCAGTGCCAGACACAGGGGATTTAAGGCATGTTCACACTTGCTGGGCAG
GGAGGGGGAAGAGAGGGAGAAGGAAGGGTTAGAGATGAATGTGTATCCGCAGTCACAGCAGAAAGCCATGAGAGCAGGGGAAACAAGGGGCTTCGAGCAC
GCTCCATGCCAGGAGGCATCTGTTGATTTCTGACCATTATCAAGAGTTGTAGGATGCAGGGCTAAATTGCAAAATAAAATAAAATAGCCAGCGTACACAA
TGAGATATTCTAAACTTCCATTCTGTTTTCTTTTCACATTGGCTCCATCACTGGTGACTGATGAAGAGCATCCTCTTTATTCAGTATAAGCCGGCAGCAA
GCAGTTCTACCTAACGTCCCACATCCTTCTCATGCCAACACTTCTGTAATTGATCATTATAAAGAAAAAACAAGGTAACAGTCATAGTTCACCTGTCTCT
TATCTATTCACTTCTGGTGCCACAACTGTTTATCCTTTTTTGAAGAAAATAAGGGAACAGAAATGCCTTTTTGTATTGCAATCGAAATGAAAGAAGAGTT
GATGTTAAAAAAACAAAAGTCAAGTGATTTATTATATACAGTGGGCGTTCAAGTCTAGTCGAGCAAGCTCAGGAGAATGTAATTAAATAATTTTATATTT
TTTAATTTATTTTGTATCTCACCTGTCATGGATGAATTCATTCACTGAATATGTAATATTGAACTTAAAAAAAAAAAAAAAAAAA
  • refseq_TRPM3.F6 (forward primer)
  • refseq_TRPM3.R6 (reverse primer)
  • Single exon skipping

Frame 0

SCSKMKATGAAPGTAFASTQNQCSGSEILDRKS
IL*KRMCPHHTQHQRPP*VLLWASDRPACWPHPQ
YLRASE*EK*KSPLPK*HPV*KVVHQQTHSTQP
YGCFWDH*VPRRWPFQQSHVCASIF*YKT*SPL
TPDDQGMAVGASQASHLCPWGPAEL*TPAKTQAS
LWERAHQSSNDNWSVDIHWRG*HRCYSSCWRCL
EGSCL*VSRKDMHHRYCPLGNCGKPGGPHWKRC
CPAIPDHVQSHEQAHCSQQHAFPLHSG*QRDHWK
IWSRGETSKTTGKAYFTPEDKHKMPAVFLS*LP
LVLFILG*LPVRLSWNRSRCSCGGTHSGRRTQC
DLDCFGVPSRHPSRASGCL*WEWTGIGHPGLWA*
ILRRRRTDK*IFEGPAVGDYTEDFHIHSNPSSA
SVHHPHGVHEEEGIDYGISDGIRRTPGH*FGYP
DSFTQRSQCLGPRPTELSFSLEQSRHRSQPDLYL
RATVAGGISGASHVGCLSSGQSGFCEITHREWS
KHAPFSHHLQTRGIVQYETWALKYIVPLGQGCQ
KGEPAPRLQNQPD*HRPGDRVPDGRGLSLQLHAQ
ALPDPLPQPLRPQEG*YSLEARKKDNQET*RRG
GH*LG*S*DQPLPLPFP*AHGVGCSHEAAEDGP
VLLAAR*GGHGQGPGGLQALQSHGS*GL*ERHG*
RHFPGAESQFQRLWPAGCGAPGPVLQAGRTAGH
ETADV*AEELEQRHVPAACRGCQTPRLHRAHVQ
PDAAHRHVDGPAPHAQELRPQGNSGNSTSSFNSQ
LGVQEQRRHALYVSGPGNPPPREGGRRTREAHK
GKRGRGHGAHSNVGTKQRGVLQEEG*RGSSEQA
PVNPPRQKNL*ILQCTHREVLVLHTGVYRIPDAL
QLYRVSEDGTLAVHPGMDRNLLYFHPGNRKDER
DSDVRAREVATESEGMAAGVLECHGPHRHPSVF
CRNDPSSPRPALQE*REGHLLREHHLLVYPSPRH
LRREQVFGPVCNDDWKNDDRHDVLCHHYAGGSD
ELWGRQASHPFSQ*GAIMETGQEHLLHALLDDL
WGSVCGPDRPSLWTE*DPRGW*NNPAASLQDRSL
DRAGHHGLLPLSGKHLAGQPPHCCL*QYIF*SK
IDIQPSLEVSEVSAHHDFP*KASSAPTTDHLQP
HDHDIPAPVLPMEETRERPG*KGLRPETLHNR**
AQEST*L*RAMHRRILQRKG*SVQLI***EDTG
DFRKGGEHVYAAGGSQRERALHEGFTPDRGHPA
GAAGRPYRAHGHGPGAPDRSGAGRVQQNPLEDLV
RLHGRRLHCPSEQLQQPGREHLQAPREYRPCR*
GDHVPNFSNLNAPYAKPFFLFGQYERQRWYRKV
GKYF*RKVPEPTPGY*FPLCSKRTQSSCSPCQHL
GHCS*FQKTIIVYRHLCLCYG*APL*YRPSGQF
REHPWAGRAKLFNSSTFHSPFK*CLCNTCTHRQ
TSKPEH*F*GHHLHGH*IFFFRLHPPPRMPKPLG
LRASDVPHH*AFQK*PLPSHHTLSSRRGSHCEI
S*LYVFPLKELLCQLWGACKNSRIHKYYRLY*H
KVCQCPSSNCGQSCLPWRSWRQSGGLNLLPSRAR
SRTESPQL*Q*GE*GQRPQSHHCNILPGG**LR
ENPVQQHHCSQDRARQQLLGRGAKCAICTHQEE
LLHQ*QTRQAAEHSKPAKSLPEKQVLQAGGPRGQ
PVHEETVQNIGFPKL*KQAQLNLLNIRHRRLKN
PALKFSPTPVFPLSLNHTCFILS*AKQAMLWEV
LTQR*LLGHRSRKHLI*PSARHRGFKACSHLLGR
EGEEREKEGLEMNVYPQSQQKAMRAGETRGFEH
APCQEASVDF*PLSRVVGCRAKLQNKIK*PAYT
MRYSKLPFCFLFTLAPSLVTDEEHPLYSV*AGSK
QFYLTSHILLMPTLL*LIIIKKKQGNSHSSPVS
YLFTSGATTVYPFLKKIREQKCLFVLQSK*KKS
*C*KNKSQVIYYIQWAFKSSRASSGECN*IILYF
LIYFVSHLSWMNSFTEYVILNLKKKKKK

Frame 1

AAAK*KQQELLRGLLLPVPRISAQAQKSWIERA
FYKRECVHIIPSTKDPHRCCCGRLIGQHVGLTP
SISVLQNEKNESRLSRNDIQSEKWSISKHTQLSP
TDAFGTIEFQGGGHSNKAMYVRVSFDTKPDLLL
HLMTKEWQLELPKLLISVHGGLQNFELQPKLKQ
VFGKGLIKAAMTTGAWIFTGGVNTGVIRHVGDAL
KDHASKSRGKICTIGIAPWGIVENQEDLIGRDV
VRPYQTMSNPMSKLTVLNSMHSHFILADNGTTG
KYGAEVKLRRQLEKHISLQKINTRCLPFFSLDSR
LFYSFWGSCQLDSVGIGQGVPVVALIVEGGPNV
ISIVLEYLRDTPPVPVVVCDGSGRASDILAFGH
KYSEEGGLINESLRDQLLVTIQKTFTYTRTQAQH
LFIILMECMKKKELITVFRMGSEGHQDIDLAIL
TALLKGANASAPDQLSLALAWNRVDIARSQIFI
YGQQWPVGSLEQAMLDALVLDRVDFVKLLIENGV
SMHRFLTISRLEELYNTRHGPSNTLYHLVRDVK
KGNLPPDYRISLIDIGLVIEYLMGGAYRCNYTR
KRFRTLYHNLFGPKRDDIPLRRGRKTTKKREEEV
DIDLDDPEINHFPFPFHELMVWAVLMKRQKMAL
FFWQHGEEAMAKALVACKLCKAMAHEASENDMV
DDISQELNHNSRDFGQLAVELLDQSYKQDEQLAM
KLLTYELKNWSNATCLQLAVAAKHRDFIAHTCS
QMLLTDMWMGRLRMRKNSGLKVILGILLPPSIL
SLEFKNKDDMPYMSQAQEIHLQEKEAEEPEKPTK
EKEEEDMELTAMLGRNNGESSRKKDEEEVQSKH
RLIPLGRKIYEFYNAPIVKFWFYTLAYIGYLML
FNYIVLVKMERWPSTQEWIVISYIFTLGIEKMRE
ILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFS
VGMILRLQDQPFRSDGRVIYCVNIIYWYIRLLD
IFGVNKYLGPYVMMIGKMMIDMMYFVIIMLVVLM
SFGVARQAILFPNEEPSWKLAKNIFYMPYWMIY
GEVFADQIDPPCGQNETREDGKIIQLPPCKTGA
WIVPAIMACYLLVANILLVNLLIAVFNNTFFEVK
SISNQVWKFQRYQLIMTFHERPVLPPPLIIFSH
MTMIFQHLCCRWRKHESDPDERDYGLKLFITDD
ELKKVHDFEEQCIEEYFREKDDRFNSSNDERIRV
TSERVENMSMRLEEVNEREHSMKASLQTVDIRL
AQLEDLIGRMATALERLTGLERAESNKIRSRTS
SDCTDAAYIVRQSSFNSQEGNTFKLQESIDPAGE
ETMSPTSPTLMPRMRSHSFYSVNMKDKGGIEKL
ESIFKERSLSLHRATSSHSVAKEPKAPAAPANT
LAIVPDSRRPSSCIDIYVSAMDELHCDIDPLDNS
VNILGLGEPSFSTPVPSTAPSSSAYATLAPTDR
PPSRSIDFEDITSMDTRSFSSDYTHLPECQNPW
DSEPPMYHTIERSKSSRYLATTPFLLEEAPIVKS
HSFMFSPSRSYYANFGVPVKTAEYTSITDCIDT
RCVNAPQAIADRAAFPGGLGDKVEDLTCCHPER
EAELSHPSSDSEENEAKGRRATIAISSQEGDNSE
RTLSNNITVPKIERANSYSAEEPSAPYAHTRKS
FSISDKLDRQRNTASLRNPFQRSKSSKPEGRGD
SLSMRRLSRTSAFQSFESKHN*TFLISATEGSRI
QP*NSLQLQFFPFP*IIPALFLAEQNKQCFGRC
*LKGDFWATDQESI*SDPVPDTGDLRHVHTCWA
GRGKRGRRKG*R*MCIRSHSRKP*EQGKQGASST
LHARRHLLISDHYQEL*DAGLNCKIK*NSQRTQ
*DILNFHSVFFSHWLHHW*LMKSILFIQYKPAA
SSST*RPTSFSCQHFCN*SL*RKNKVTVIVHLSL
IYSLLVPQLFILF*RK*GNRNAFLYCNRNERRV
DVKKTKVK*FIIYSGRSSLVEQAQENVIK*FYI
F*FILYLTCHG*IHSLNM*Y*T*KKKKK

Frame 2

LQQNESNRSCSGDCFCQYPESVLRLRNPG*KEH
FIKENVSTSYPAPKTPIGVAVGV**ASMLASPP
VSPCFRMRKMKVASPEMTSSLKSGPSANTLNSA
LRMLLGPLSSKEVAIPTKPCMCEYLLIQNLISSY
T**PRNGSWSFPSFSSLSMGACRTLNSSQNSSK
SLGKGSSKQQ*QLERGYSLEGLTQVLFVMLAMP
*RIMPLSLEERYAP*VLPPGELWKTRRTSLEEML
SGHTRPCPIP*ASSLFSTACIPTSFWLTTGPLE
NMEQR*NFEDNWKSIFHSRR*TQDACRFSLLTP
ACFIHFGVVAS*TQLESVKVFLWWHS*WKEDPM*
SRLFWSTFETPLPCQWLSVMGVDGHRTSWPLGI
NTQKKAD**MNL*GTSCW*LYRRLSHTLEPKLS
ICSSSSWSA*RRRN*LRYFGWDQKDTRTLIWLS*
QLYSKEPMPRPQTN*A*L*PGTESTSLAARSLF
TGNSGRWDLWSKPCWMP*FWTEWIL*NYS*RME
*ACTVFSPSPD*RNCTIRDMGPQIHCTTWSGMSK
RGTCPQTTESA*LTSAW*SST*WAGLIAATTRA
SASGPSTTTSSAPRGMIFP*GEEERQPRNVKKR
WTLTWMILRSTTSPSLSMSSWCGLFS*SGRRWPC
SSGSTVRRPWPRPWWPASSAKPWLMRPLRTTWL
TTFPRS*ITIPETLASWLWSSWTSPTSRTNSWP
*NC*RMS*RTGATPRACSLPWLPNTATSSRTRAA
RCCSPTCGWAGSACARTQASR*FWEFYFLLQFS
AWSSRTKTTCPICLRPRKSTSKRRRQKNQRSPQ
RKKRKRTWSSQQCWDETTGSPPGRRMKRKFRAST
G*SPSAEKSMNSTMHPS*SSGSTHWRISDT*CS
STISC**RWNAGRPPRNGS*SPIFSPWE*KR*E
RF*CQSQGSCYRK*RYGCRSTGMSRTSSPSFCFL
SE*SFVSKTSPSGVTGGSSTA*TSFTGISVS*T
SSA*TSIWARM***LEK***T*CTLSSLCWWF*
*ALGSPGKPSFFPMRSHHGNWPRTSSTCPIG*FM
GKCLRTR*TLPVDRMRPERMVK*SSCLPARQEL
GSCRPSWPATS*WQTSCWSTSSLLSLTIHFLK*
NRYPTKSGSFRGISSS*LSMKGQFCPHH*SSSAT
*P*YSSTCAADGGNTRATRMKGTTA*NSS*PMM
SSRKYMTLKSNA*KNTSEKRMIGSTHLMMRGYG
*LQKGWRTCLCGWRKSTRESTP*RLHSRPWTSGW
RSWKTLSGAWPRPWSA*QVWSGPSPTKSARGPR
QTARTPPTLSVRAASTARKGTPSSSKRV*TLQV
RRPCPQLLQP*CPVCEAILSIRSI*KTKVV*KSW
KVFLKKGP*AYTGLLVPTL*QKNPKLLQPLPTP
WPLFLIPEDHHRV*TSMSLLWMSSTVI*TLWTI
P*TSLGWASQAFQLQYLPQPLQVVPMQHLHPQTD
LQAGALILRTSPPWTLDLFLQTTPTSQNAKTPG
TQSLRCTTPLSVPKVAAT*PPHPFF*KRLPL*N
LIALCFPPQGAIMPTLGCL*KQQNTQVLQTVLTQ
GVSMPLKQLRTELPSLEVLETKWRT*LAAIQSE
KQN*VTPALTVRRMRPKAAEPPLQYPPRRVITQ
REPCPTTSLFPR*SAPTATRQRSQVRHMHTPGRA
SPSVTNSTGSGTQQACEIPSREASPPSRRAEGT
ACP*GDCPEHRLSKALKASTTKPS*YPPQKAQE
SSPKILSNSSFSPFLESYLLYS*LSKTSNALGGV
NSKVTSGPQIKKAFDLTQCQTQGI*GMFTLAGQ
GGGREGEGRVRDECVSAVTAESHESRGNKGLRA
RSMPGGIC*FLTIIKSCRMQG*IAK*NKIASVHN
EIF*TSILFSFHIGSITGD**RASSLFSISRQQ
AVLPNVPHPSHANTSVIDHYKEKTR*QS*FTCL
LSIHFWCHNCLSFFEENKGTEMPFCIAIEMKEEL
MLKKQKSSDLLYTVGVQV*SSKLRRM*LNNFIF
FNLFCISPVMDEFIH*ICNIELKKKKKK

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