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Sequences

Sequence NM_007308

GAATTCATTAGCCATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCTGCTGAGAAAACCAAACAGGGTGTGGCAGAAGCA
GCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTGTGGCAACAGTGGCTGAGAAGACCAAAGAGCAAG
TGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGCAGGGAGCATTGCAGCAGCCACTGGCTTTGTCAA
AAAGGACCAGTTGGGCAAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAAGAAATATCTTTGCTCCCAGTTTCTTGAGATCTGCTGACAGATGTTCCA
TCCTGTACAAGTGCTCAGTTCCAATGTGCCCAGTCATGACATTTCTCAAAGTTTTTACAGTGTATCTCGAAGTCTTCCATCAGCAGTGATTGAAGTATCT
GTACCTGCCCCCACTCAGCATTTCGGTGCTTCCCTTTCACTGAAGTGAATACATGGTAGCAGGGTCTTTGTGTGCTGTGGATTTTGTGGCTTCAATCTAC
GATGTTAAAACAAATTAAAAACACCTAAGTGACTACCACTTATTTCTAAATCCTCACTATTTTTTTGTTGCTGTTGTTCAGAAGTTGTTAGTGATTTGCT
ATCATATATTATAAGATTTTTAGGTGTCTTTTAATGATACTGTCTAAGAATAATGACGTATTGTGAAATTTGTTAATATATATAATACTTAAAAATATGT
GAGCATGAAACTATGCACCTATAAATACTAAATATGAAATTTTACCATTTTGCGATGTGTTTTATTCACTTGTGTTTGTATATAAATGGTGAGAATTAAA
ATAAAACGTTATCTCATTGCAAAAATATTTTATTTTTATCCCATCTCACTTTAATAATAAAAATCATGCTTATAAGCAACATGAATTAAGAACTGACACA
AAGGACAAAAATATAAAGTTATTAATAGCCATTTGAAGAAGGAGGAATTTTAGAAGAGGTAGAGAAAATGGAACATTAACCCTACACTCGGAATTCCCTG
AAGCAACACTGCCAGAAGTGTGTTTTGGTATGCACTGGTTCCTTAAGTGGCTGTGATTAATTATTGAAAGTGGGGTGTTGAAGACCCCAACTACTATTGT
AGAGTGGTCTATTTCTCCCTTCAATCCTGTCAATGTTTGCTTTACGTATTTTGGGGAACTGTTGTTTGATGTGTATGTGTTTATAATTGTTATACATTTT
TAATTGAGCCTTTTATTAACATATATTGTTATTTTTGTCTCGAAATAATTTTTTAGTTAAAATCTATTTTGTCTGATATTGGTGTGAATGCTGTACCTTT
CTGACAATAAATAATATTCGACCATG
  • refseq_SNCA.F2 (forward primer)
  • refseq_SNCA.R2 (reverse primer)
  • Single exon skipping

Frame 0

EFISHGCIHERTFKGQGGSCGCC*ENQTGCGRS
SRKDKRGCSLCRLQNQGGSGAWCGNSG*EDQRAS
DKCWRSSGDGCDSSSPEDSGGSREHCSSHWLCQ
KGPVGQGRVSRLRT*SLRNIFAPSFLRSADRCS
ILYKCSVPMCPVMTFLKVFTVYLEVFHQQ*LKYL
YLPPLSISVLPFH*SEYMVAGSLCAVDFVASIY
DVKTN*KHLSDYHLFLNPHYFFVAVVQKLLVIC
YHIL*DF*VSFNDTV*E**RIVKFVNIYNT*KYV
SMKLCTYKY*I*NFTILRCVLFTCVCI*MVRIK
IKRYLIAKIFYFYPISL***KSCL*AT*IKN*H
KGQKYKVINSHLKKEEF*KR*RKWNINPTLGIP*
SNTARSVFWYALVP*VAVINY*KWGVEDPNYYC
RVVYFSLQSCQCLLYVFWGTVV*CVCVYNCYTF
LIEPFINIYCYFCLEIIF*LKSILSDIGVNAVPF
*Q*IIFDH

Frame 1

NSLAMDVFMKGLSKAKEGVVAAAEKTKQGVAEA
AGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQ
VTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVK
KDQLGKEGYQDYEPEA*EISLLPVS*DLLTDVP
SCTSAQFQCAQS*HFSKFLQCISKSSISSD*SI
CTCPHSAFRCFPFTEVNTW*QGLCVLWILWLQST
MLKQIKNT*VTTTYF*ILTIFLLLLFRSC**FA
IIYYKIFRCLLMILSKNNDVL*NLLIYIILKNM
*A*NYAPINTKYEILPFCDVFYSLVFVYKW*ELK
*NVISLQKYFIFIPSHFNNKNHAYKQHELRTDT
KDKNIKLLIAI*RRRNFRRGRENGTLTLHSEFP
EATLPEVCFGMHWFLKWL*LIIESGVLKTPTTIV
EWSISPFNPVNVCFTYFGELLFDVYVFIIVIHF
*LSLLLTYIVIFVSK*FFS*NLFCLILV*MLYL
SDNK*YSTM

Frame 2

IH*PWMYS*KDFQRPRRELWLLLRKPNRVWQKQ
QERQKRVFSM*APKPRREWCMVWQQWLRRPKSK
*QMLEEQW*RV*QQ*PRRQWREQGALQQPLALS
KRTSWARKGIKTTNLKPKKYLCSQFLEIC*QMFH
PVQVLSSNVPSHDISQSFYSVSRSLPSAVIEVS
VPAPTQHFGASLSLK*IHGSRVFVCCGFCGFNL
RC*NKLKTPK*LPLISKSSLFFCCCCSEVVSDLL
SYIIRFLGVF**YCLRIMTYCEIC*YI*YLKIC
EHETMHL*ILNMKFYHFAMCFIHLCLYINGEN*
NKTLSHCKNILFLSHLTLIIKIMLISNMN*ELTQ
RTKI*SY**PFEEGGILEEVEKMEH*PYTRNSL
KQHCQKCVLVCTGSLSGCD*LLKVGC*RPQLLL
*SGLFLPSILSMFALRILGNCCLMCMCL*LLYIF
N*AFY*HILLFLSRNNFLVKIYFV*YWCECCTF
LTINNIRP

Sequence NM_000345

GGAGTGGCCATTCGACGACAGTGTGGTGTAAAGGAATTCATTAGCCATGGATGTATTCATGAAAGGACTTTCAAAGGCCAAGGAGGGAGTTGTGGCTGCT
GCTGAGAAAACCAAACAGGGTGTGGCAGAAGCAGCAGGAAAGACAAAAGAGGGTGTTCTCTATGTAGGCTCCAAAACCAAGGAGGGAGTGGTGCATGGTG
TGGCAACAGTGGCTGAGAAGACCAAAGAGCAAGTGACAAATGTTGGAGGAGCAGTGGTGACGGGTGTGACAGCAGTAGCCCAGAAGACAGTGGAGGGAGC
AGGGAGCATTGCAGCAGCCACTGGCTTTGTCAAAAAGGACCAGTTGGGCAAGAATGAAGAAGGAGCCCCACAGGAAGGAATTCTGGAAGATATGCCTGTG
GATCCTGACAATGAGGCTTATGAAATGCCTTCTGAGGAAGGGTATCAAGACTACGAACCTGAAGCCTAAGAAATATCTTTGCTCCCAGTTTCTTGAGATC
TGCTGACAGATGTTCCATCCTGTACAAGTGCTCAGTTCCAATGTGCCCAGTCATGACATTTCTCAAAGTTTTTACAGTGTATCTCGAAGTCTTCCATCAG
CAGTGATTGAAGTATCTGTACCTGCCCCCACTCAGCATTTCGGTGCTTCCCTTTCACTGAAGTGAATACATGGTAGCAGGGTCTTTGTGTGCTGTGGATT
TTGTGGCTTCAATCTACGATGTTAAAACAAATTAAAAACACCTAAGTGACTACCACTTATTTCTAAATCCTCACTATTTTTTTGTTGCTGTTGTTCAGAA
GTTGTTAGTGATTTGCTATCATATATTATAAGATTTTTAGGTGTCTTTTAATGATACTGTCTAAGAATAATGACGTATTGTGAAATTTGTTAATATATAT
AATACTTAAAAATATGTGAGCATGAAACTATGCACCTATAAATACTAAATATGAAATTTTACCATTTTGCGATGTGTTTTATTCACTTGTGTTTGTATAT
AAATGGTGAGAATTAAAATAAAACGTTATCTCATTGCAAAAATATTTTATTTTTATCCCATCTCACTTTAATAATAAAAATCATGCTTATAAGCAACATG
AATTAAGAACTGACACAAAGGACAAAAATATAAAGTTATTAATAGCCATTTGAAGAAGGAGGAATTTTAGAAGAGGTAGAGAAAATGGAACATTAACCCT
ACACTCGGAATTCCCTGAAGCAACACTGCCAGAAGTGTGTTTTGGTATGCACTGGTTCCTTAAGTGGCTGTGATTAATTATTGAAAGTGGGGTGTTGAAG
ACCCCAACTACTATTGTAGAGTGGTCTATTTCTCCCTTCAATCCTGTCAATGTTTGCTTTACGTATTTTGGGGAACTGTTGTTTGATGTGTATGTGTTTA
TAATTGTTATACATTTTTAATTGAGCCTTTTATTAACATATATTGTTATTTTTGTCTCGAAATAATTTTTTAGTTAAAATCTATTTTGTCTGATATTGGT
GTGAATGCTGTACCTTTCTGACAATAAATAATATTCGACCATG
  • refseq_SNCA.F2 (forward primer)
  • refseq_SNCA.R2 (reverse primer)
  • Single exon skipping

Frame 0

GVAIRRQCGVKEFISHGCIHERTFKGQGGSCGC
C*ENQTGCGRSSRKDKRGCSLCRLQNQGGSGAWC
GNSG*EDQRASDKCWRSSGDGCDSSSPEDSGGS
REHCSSHWLCQKGPVGQE*RRSPTGRNSGRYAC
GS*Q*GL*NAF*GRVSRLRT*SLRNIFAPSFLRS
ADRCSILYKCSVPMCPVMTFLKVFTVYLEVFHQ
Q*LKYLYLPPLSISVLPFH*SEYMVAGSLCAVD
FVASIYDVKTN*KHLSDYHLFLNPHYFFVAVVQK
LLVICYHIL*DF*VSFNDTV*E**RIVKFVNIY
NT*KYVSMKLCTYKY*I*NFTILRCVLFTCVCI
*MVRIKIKRYLIAKIFYFYPISL***KSCL*AT*
IKN*HKGQKYKVINSHLKKEEF*KR*RKWNINP
TLGIP*SNTARSVFWYALVP*VAVINY*KWGVE
DPNYYCRVVYFSLQSCQCLLYVFWGTVV*CVCVY
NCYTFLIEPFINIYCYFCLEIIF*LKSILSDIG
VNAVPF*Q*IIFDH

Frame 1

EWPFDDSVV*RNSLAMDVFMKGLSKAKEGVVAA
AEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHG
VATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGA
GSIAAATGFVKKDQLGKNEEGAPQEGILEDMPV
DPDNEAYEMPSEEGYQDYEPEA*EISLLPVS*D
LLTDVPSCTSAQFQCAQS*HFSKFLQCISKSSIS
SD*SICTCPHSAFRCFPFTEVNTW*QGLCVLWI
LWLQSTMLKQIKNT*VTTTYF*ILTIFLLLLFR
SC**FAIIYYKIFRCLLMILSKNNDVL*NLLIYI
ILKNM*A*NYAPINTKYEILPFCDVFYSLVFVY
KW*ELK*NVISLQKYFIFIPSHFNNKNHAYKQH
ELRTDTKDKNIKLLIAI*RRRNFRRGRENGTLTL
HSEFPEATLPEVCFGMHWFLKWL*LIIESGVLK
TPTTIVEWSISPFNPVNVCFTYFGELLFDVYVF
IIVIHF*LSLLLTYIVIFVSK*FFS*NLFCLILV
*MLYLSDNK*YSTM

Frame 2

SGHSTTVWCKGIH*PWMYS*KDFQRPRRELWLL
LRKPNRVWQKQQERQKRVFSM*APKPRREWCMV
WQQWLRRPKSK*QMLEEQW*RV*QQ*PRRQWRE
QGALQQPLALSKRTSWARMKKEPHRKEFWKICLW
ILTMRLMKCLLRKGIKTTNLKPKKYLCSQFLEI
C*QMFHPVQVLSSNVPSHDISQSFYSVSRSLPS
AVIEVSVPAPTQHFGASLSLK*IHGSRVFVCCGF
CGFNLRC*NKLKTPK*LPLISKSSLFFCCCCSE
VVSDLLSYIIRFLGVF**YCLRIMTYCEIC*YI
*YLKICEHETMHL*ILNMKFYHFAMCFIHLCLYI
NGEN*NKTLSHCKNILFLSHLTLIIKIMLISNM
N*ELTQRTKI*SY**PFEEGGILEEVEKMEH*P
YTRNSLKQHCQKCVLVCTGSLSGCD*LLKVGC*R
PQLLL*SGLFLPSILSMFALRILGNCCLMCMCL
*LLYIFN*AFY*HILLFLSRNNFLVKIYFV*YW
CECCTFLTINNIRP

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