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Sequences

Sequence NM_181349

GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGGACTGGGCTCG GCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTGGGCCGCGGAGTTTGTGTCCC GGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGC TGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCAAGATCCGTCTGACAGTGTTATGTGCCAAGAACCTTGCAAA GAAAGACTTCTTCAGGCTCCCTGACCCTTTTGCAAAGATTGTCGTGGATGGGTCTGGGCAGTGCCACTCAACCGACACTGTGAAAAACACATTGGACCCA AAGTGGAACCAGCACTATGATCTATATGTTGGGAAAACGGATTCGATAACCATTAGCGTGTGGAACCATAAGAAAATTCACAAGAAACAGGGAGCTGGCT TCCTGGGCTGTGTGCGGCTGCTCTCCAATGCCATCAGCAGATTAAAAGATACCGGATACCAGCGTTTGGATCTATGCAAACTAAACCCCTCAGATACTGA TGCAGTTCGTGGCCAGATAGTGGTCAGTTTACAGACACGAGACAGAATAGGAACCGGCGGCTCGGTGGTGGACTGCAGAGGACTGTTAGAAAATGAAGGA ACGGTGTATGAAGACTCCGGGCCTGGGAGGCCGCTCAGCTGCTTCATGGAGGAACCAGCCCCTTACACAGATAGCACCGGTGCTGCTGCTGGAGGAGGGA ATTGCAGGTTCGTGGAGTCCCCAAGTCAAGATCAAAGACTTCAGGCACAGCGGCTTCGAAACCCTGATGTGCGAGGTTCACTACAGACGCCCCAGAACCG ACCACACGGCCACCAGTCCCCGGAACTGCCCGAAGGCTACGAACAAAGAACAACAGTCCAGGGCCAAGTTTACTTTTTGCATACACAGACTGGAGTTAGC ACGTGGCACGACCCCAGGATACCAAGAGACCTTAACAGTGTGAACTGTGATGAACTTGGACCACTGCCGCCAGGCTGGGAAGTCAGAAGTACAGTTTCTG GGAGGATATATTTTGTAGATCATAATAACCGAACAACCCAGTTTACAGACCCAAGGTTACACCACATCATGAATCACCAGTGCCAACTCAAGGAGCCCAG CCAGCCGCTGCCACTGCCCAGTGAGGGCTCTCTGGAGGACGAGGAGCTTCCTGCCCAGAGATACGAAAGAGATCTAGTCCAGAAGCTGAAAGTCCTCAGA CACGAACTGTCGCTTCAGCAGCCCCAAGCTGGTCATTGCCGCATCGAAGTGTCCAGAGAAGAAATCTTTGAGGAGTCTTACCGCCAGATAATGAAGATGC GACCGAAAGACTTGAAAAAACGGCTGATGGTGAAATTCCGTGGGGAAGAAGGTTTGGATTACGGTGGTGTGGCCAGGGAGTGGCTTTACTTGCTGTGCCA TGAAATGCTGAATCCTTATTACGGGCTCTTCCAGTATTCTACGGACAATATTTACATGTTGCAAATAAATCCGGATTCTTCAATCAACCCCGACCACTTG TCTTATTTCCACTTTGTGGGGCGGATCATGGGGCTGGCTGTGTTCCATGGACACTACATCAACGGGGGCTTCACAGTGCCCTTCTACAAGCAGCTGCTGG GGAAGCCCATCCAGCTCTCAGATCTGGAATCTGTGGACCCAGAGCTGCATAAGAGCTTGGTGTGGATCCTAGAGAACGACATCACGCCTGTACTGGACCA CACCTTCTGCGTGGAACACAACGCCTTCGGGCGGATCCTGCAGCATGAACTGAAACCCAATGGCAGAAATGTGCCAGTCACAGAGGAGAATAAGAAAGAA TACGTCCGGTTGTATGTAAACTGGAGGTTTATGAGAGGAATCGAAGCCCAGTTCTTAGCTCTGCAGAAGGGGTTCAATGAGCTCATCCCTCAACATCTGC TGAAGCCTTTTGACCAGAAGGAACTGGAGCTGATCATAGGCGGCCTGGATAAAATAGACTTGAACGACTGGAAGTCGAACACGCGGCTGAAGCACTGTGT GGCCGACAGCAACATCGTGCGGTGGTTCTGGCAAGCGGTGGAGACGTTCGATGAAGAAAGGAGGGCCAGGCTCCTGCAGTTTGTGACTGGGTCCACGCGA GTCCCGCTCCAAGGCTTCAAGGCTTTGCAAGGTTCTACAGGCGCGGCAGGGCCCCGGCTGTTCACCATCCACCTGATAGACGCGAACACAGACAACCTTC CGAAGGCCCATACCTGCTTTAACCGGATCGACATTCCACCATATGAGTCCTATGAGAAGCTCTACGAGAAGCTGCTGACAGCCGTGGAGGAGACCTGCGG GTTTGCTGTGGAGTGAAAAGCAACCAAAGGCAACAGAGTCTAGCTCATGGCCACCAGACCAAAAGCATCCAGCTTCTGTGCACCTCCTGCAAAGCTGGCA GAGGCCCTGGAATTCCAGATCACCTGAGGGGAAAGGGTTGTCTCTCTCCTTTCTGTTGGGGGAGGGGGATGGGGGACTTTTGTTGGTGGCTCCCACCCAT ATATCCCTCCTTTACCATAGTACTCCCACCCACTTCCATCACCCATCCAATAAAATGCAGCCAGGTTTAGCCTTTGGCTTTGGTCACACAGGATATTCTG CTGTGTTGCAACCCATGTGGTGATAAGGCTCACAGCCCTGAGCTCTTTACGGGAGCATCAACTCACAGTTAGGGGACTGGGCGTGGCTGATTGAGGGTTT GGAACTGGTGGCTATGCCAGCTATTCCATCTCAAAACAGCCTTGAGGCCCCTTTTCAATTTGAGCAGCTGCTAGATATCTTATCAGAGCTCAGATTCCAG ATTTCACATCCCAGCAGCCGGTTCTGGGTAGCAGATCAATTTCCAACTGGAAAATAACTATATAATGTATGCTTATTGGAATTCTGCCACAGCAGGAAGC TTGAGTCAAAATGTGTTTCCCCTTTGAAAGGAGAAGGAATTGGAGCAGCTTTTCCTGGAGGCCCAGGATATTTCTTTTCTGGGTATCTTGGCTGAAAATT TTGTTTTACATAGAGAAAAACGATCTTTTAAGGGTCCCTTTTGCTGCATTATCTGTCCAGTTTGACTTTTTTTTCAGTGAAAACACCATGTCATGGAGTG TAGGAAAGAGCAGACCAAAATCAGCCCTAGAGCCAACCAGTCAGTCCCAAAGCTGTGACCTCTGTGCCACTGTTGTCCATAGAAGAGCATCGACTGTGTC ACTTAAAATATTAGTAAACCATGATGCAGCAACTGCTAAGAGCTAAACTAACAAAATTGTGTCATCATAGCTGCTGGCTTGGTGTGAACTCGCTTAAAAG CAATGGTGAAAGGATAACCTCGATGATGTAAATCCACCCAAAGATACTGTTCTACAAAAAGTAGGGTGTGGACGCAAACCTGTGACAGCAGAGGGGGACG ACTTCACACTCACTGCCTCATGTGGCCCCTTTCCCAGTGGCAGCTGGTGACACTAACGATTGCTACTCGGTTCACTTGCCCAGATGTCTTCATATGATGA GCAAGGCCAGAAGCAAGGCTAGATTCGAAGTTTCTGACACCATTTCCAGTTTGCACAAAAGTCAGTATTTTATCTTAAAGTGGCTTGATTTCCAATAGCT GAACTTGGGCAGAAAACAGCAGGCCAATGTTCCTATGTGGTTTCTTTGTTGTTGTTTTTGTTTGGGGTGGGGGCAAGTACAGGGTAATTCATGAGCAAGA CATTTCACTGCTGTCGAAGTCTCTGGGATCCCGCTGTGGGTCTGAGATGGCCTGGGAAGGACCTTGTGGACAATGGTTTTATCTGTTCTTTTTGTCACTG TTAATTTCTGGGCTGCTGAGGTTCTAGAATAGAAGGGCTGCCAAATGAGGTTTGCTGCAGGAGGAAAGTTTAATCCCCCATTCCAAAAGTCCAGGCCAAA TGGTGGGCTTAGCCTCTTTGAAAAGTTCTGCCTTGCCCCCACAGGTGGGCACATCCTGTGTCTCATTCACCATGATGCTTCCTGAGGGTGTTCTAGAAGC CCGTTCCCCAGTGGCTGTATCCAGCCTTTCCTTGCATCATCTTCCTCTTGAAGGTGAGGAAGTGAAAACTACAGACCTCCCCCGGACAGCCCACTCTCTA TCACGAGCCTAACCCGCGGGAGGCGGAAGAGACATCCATTCGAGAACTGAAGCGGCCTCCGGGATGAGGTCAGAGGCCCCACCTGATTTTCCTGGTGGTG GTATCCAAAATCTTCAGTAACTAGGAAGGAAACCAGGGTCTCATGGTTTAAAAGACTTTGAAGCAGGAATGTTGCATTTGACGCCTTTAAAACTACCTTT TTGCTGTTGGGAGGAGTCGGGGGCGAGCCTTAGCAGCTGCACCGCCATCCCCATGCTGGTTGGTGCTGCCCTGCCTCTCGTGCCGGGTGTTGCTTCAGCC CAGAGCCAGAGGGCTGGGTCCCGGGTCCTCCACAGGTGACCCCGGTGGACACACGCGTTCCCATCCTGGCCTCCGTCTCTGCTTTTCCACTTCTACCTGC GTGTGGGTTTGCCGCCTTGTCATCGGTTGTGTGAGTGTCGCAGACCTTTCCAGAGCTCCGGTTCACTCTTTCCAAACAGGCCTCCCTGTCGGTGGCACTG CACTCCTAGAACCTTCAGTTTCTACGATGGTTTGTTTGGTCCTTTTGAACCACCCCAAAGAACTCAACATGGCAAAGCAAATGGTAAAAGCTTCCCGACT GTTCTACTTTGGGTCCGCGCGAAGCCCACTCACGTGTGATCTGTGTTGCCCCTCTCGGTGGTCCCAGGCGATCCAGCCATGCCCCCTGCCCCTCTGCCCA GATGCTTCAGGGGCCCGGCTTTTCAGGCTTGCCCTCACCAGCGGCCGTCAGCCGACACTCAGGGATGTAGCTAACACCACTCCGCCAGTGCTTTCAGTAG GAAGAGCTGAGGCTGCCTGGGAGGCCCGGGGCGACCGGAAAAGGGCTCTCTCAAGTTCTGAAAAGAGAATCTGCCACCAGATCGAATTTCGACCCCTGAG CTTGTTCGGACGTATGGTCCAAATTCAGATTAAGGTGGTCACCCAACCCGAGATGTCAGGAAAGGCCTTCTGCAGAGAAAATGTCCCCCCACCCGCCATC TGCAGCCAGGTGTGTGCCACACGGCAGCCTTCCCGAAACATAGTATGGATTTTAAAAATGTGTTTATTTTTGTTTCTCAACCACTTTATAACGTATTTTT TAATTTATTTTGTAATGTCTTGTTTTGAAGTATTGCTGCTATCCTTGTTATCCTTCCCACTGTTTTTATCACTGATTTATTTTGTGAAAGTTGTACACTA ATGTTCTATGTCAAAATCAAAAGTATTTAATGAAATACTAGTTCTATTTAATGTGGTTATGGAACCAGCTGGAAACACAAAACAAACAGTGATTGTACAG CAGGCTGGGCCCAGGAGGTCAGGTTCATTTTGTTACATATGCAATAAACTCACGACTTT

refseq_SMURF1.F2 (forward primer)
refseq_SMURF1.R2 (reverse primer)
Single exon skipping

Frame 0

GSGGSGEGGGRPALRWWRRRRRRRRRRRLGTGL GWKQRGSERRSKRRSPGSTIRLPPGRLGRGVCVP ARTPAPSPEP*P*GGGGGAGPGRAGGRWRWIRG CPIVGGRCRTPGHAGTAPASRSV*QCYVPRTLQ RKTSSGSLTLLQRLSWMGLGSATQPTL*KTHWTQ SGTSTMIYMLGKRIR*PLACGTIRKFTRNRELA SWAVCGCSPMPSAD*KIPDTSVWIYAN*TPQIL MQFVAR*WSVYRHETE*EPAARWWTAEDC*KMKE RCMKTPGLGGRSAASWRNQPLTQIAPVLLLEEG IAGSWSPQVKIKDFRHSGFETLMCEVHYRRPRT DHTATSPRNCPKATNKEQQSRAKFTFCIHRLELA RGTTPGYQETLTV*TVMNLDHCRQAGKSEVQFL GGYIL*IIITEQPSLQTQGYTTS*ITSANSRSP ASRCHCPVRALWRTRSFLPRDTKEI*SRS*KSSD TNCRFSSPKLVIAASKCPEKKSLRSLTAR**RC DRKT*KNG*W*NSVGKKVWITVVWPGSGFTCCA MKC*ILITGSSSILRTIFTCCK*IRILQSTPTTC LISTLWGGSWGWLCSMDTTSTGASQCPSTSSCW GSPSSSQIWNLWTQSCIRAWCGS*RTTSRLYWT TPSAWNTTPSGGSCSMN*NPMAEMCQSQRRIRKN TSGCM*TGGL*EESKPSS*LCRRGSMSSSLNIC *SLLTRRNWS*S*AAWIK*T*TTGSRTRG*STV WPTATSCGGSGKRWRRSMKKGGPGSCSL*LGPRE SRSKASRLCKVLQARQGPGCSPST**TRTQTTF RRPIPALTGSTFHHMSPMRSSTRSC*QPWRRPA GLLWSEKQPKATESSSWPPDQKHPASVHLLQSWQ RPWNSRSPEGKGLSLSFLLGEGDGGLLLVAPTH ISLLYHSTPTHFHHPSNKMQPGLAFGFGHTGYS AVLQPMW**GSQP*ALYGSINSQLGDWAWLIEGL ELVAMPAIPSQNSLEAPFQFEQLLDILSELRFQ ISHPSSRFWVADQFPTGK*LYNVCLLEFCHSRK LESKCVSPLKGEGIGAAFPGGPGYFFSGYLG*KF CFT*RKTIF*GSLLLHYLSSLTFFSVKTPCHGV *ERADQNQP*SQPVSPKAVTSVPLLSIEEHRLC HLKY**TMMQQLLRAKLTKLCHHSCWLGVNSLKS NGERITSMM*IHPKILFYKK*GVDANL*QQRGT TSHSLPHVAPFPVAAGDTNDCYSVHLPRCLHMM SKARSKARFEVSDTISSLHKSQYFILKWLDFQ*L NLGRKQQANVPMWFLCCCFCLGWGQVQGNS*AR HFTAVEVSGIPLWV*DGLGRTLWTMVLSVLFVT VNFWAAEVLE*KGCQMRFAAGGKFNPPFQKSRPN GGLSLFEKFCLAPTGGHILCLIHHDAS*GCSRS PFPSGCIQPFLASSSS*R*GSENYRPPPDSPLS ITSLTRGRRKRHPFEN*SGLRDEVRGPT*FSWWW YPKSSVTRKETRVSWFKRL*SRNVAFDAFKTTF LLLGGVGGEP*QLHRHPHAGWCCPASRAGCCFS PEPEGWVPGPPQVTPVDTRVPILASVSAFPLLPA CGFAALSSVV*VSQTFPELRFTLSKQASLSVAL HS*NLQFLRWFVWSF*TTPKNSTWQSKW*KLPD CSTLGPREAHSRVICVAPLGGPRRSSHAPCPSAQ MLQGPGFSGLPSPAAVSRHSGM*LTPLRQCFQ* EELRLPGRPGATGKGLSQVLKRESATRSNFDP* ACSDVWSKFRLRWSPNPRCQERPSAEKMSPHPPS AARCVPHGSLPET*YGF*KCVYFCFSTTL*RIF *FIL*CLVLKYCCYPCYPSHCFYH*FIL*KLYT NVLCQNQKYLMKY*FYLMWLWNQLETQNKQ*LYS RLGPGGQVHFVTYAINSRL

Frame 1

AAAEAARAAGVRL*GGGGGGGGGGGGGGSGLGS AGSSEGQSAAASADLPARPSACRPDAWAAEFVS RLGPRRPARSRNLEAAAAGPGRAGLGGGGAGSAA ARSLAGDVEPRDTQERLQHQDPSDSVMCQEPCK ERLLQAP*PFCKDCRGWVWAVPLNRHCEKHIGP KVEPAL*SICWENGFDNH*RVEP*ENSQETGSWL PGLCAAALQCHQQIKRYRIPAFGSMQTKPLRY* CSSWPDSGQFTDTRQNRNRRLGGGLQRTVRK*R NGV*RLRAWEAAQLLHGGTSPLHR*HRCCCWRRE LQVRGVPKSRSKTSGTAASKP*CARFTTDAPEP TTRPPVPGTARRLRTKNNSPGPSLLFAYTDWS* HVARPQDTKRP*QCEL**TWTTAARLGSQKYSFW EDIFCRS**PNNPVYRPKVTPHHESPVPTQGAQ PAAATAQ*GLSGGRGASCPEIRKRSSPEAESPQ TRTVASAAPSWSLPHRSVQRRNL*GVLPPDNEDA TERLEKTADGEIPWGRRFGLRWCGQGVALLAVP *NAESLLRALPVFYGQYLHVANKSGFFNQPRPL VLFPLCGADHGAGCVPWTLHQRGLHSALLQAAAG EAHPALRSGICGPRAA*ELGVDPRERHHACTGP HLLRGTQRLRADPAA*TETQWQKCASHRGE*ER IRPVVCKLEVYERNRSPVLSSAEGVQ*AHPSTSA EAF*PEGTGADHRRPG*NRLERLEVEHAAEALC GRQQHRAVVLASGGDVR*RKEGQAPAVCDWVHA SPAPRLQGFARFYRRGRAPAVHHPPDRREHRQPS EGPYLL*PDRHSTI*VL*EALREAADSRGGDLR VCCGVKSNQRQQSLAHGHQTKSIQLLCTSCKAG RGPGIPDHLRGKGCLSPFCWGRGMGDFCWWLPPI YPSFTIVLPPTSITHPIKCSQV*PLALVTQDIL LCCNPCGDKAHSPELFTGASTHS*GTGRG*LRV WNWWLCQLFHLKTALRPLFNLSSC*ISYQSSDSR FHIPAAGSG*QINFQLENNYIMYAYWNSATAGS LSQNVFPL*KEKELEQLFLEAQDISFLGILAEN FVLHREKRSFKGPFCCIICPV*LFFQ*KHHVMEC RKEQTKISPRANQSVPKL*PLCHCCP*KSIDCV T*NISKP*CSNC*ELN*QNCVIIAAGLV*TRLK AMVKG*PR*CKSTQRYCSTKSRVWTQTCDSRGGR LHTHCLMWPLSQWQLVTLTIATRFTCPDVFI** ARPEARLDSKFLTPFPVCTKVSILS*SGLISNS *TWAENSRPMFLCGFFVVVFVWGGGKYRVIHEQD ISLLSKSLGSRCGSEMAWEGPCGQWFYLFFLSL LISGLLRF*NRRAAK*GLLQEESLIPHSKSPGQ MVGLASLKSSALPPQVGTSCVSFTMMLPEGVLEA RSPVAVSSLSLHHLPLEGEEVKTTDLPRTAHSL SRA*PAGGGRDIHSRTEAASGMRSEAPPDFPGG GIQNLQ*LGRKPGSHGLKDFEAGMLHLTPLKLPF CCWEESGASLSSCTAIPMLVGAALPLVPGVASA QSQRAGSRVLHR*PRWTHAFPSWPPSLLFHFYL RVGLPPCHRLCECRRPFQSSGSLFPNRPPCRWHC TPRTFSFYDGLFGPFEPPQRTQHGKANGKSFPT VLLWVRAKPTHV*SVLPLSVVPGDPAMPPAPLP RCFRGPAFQACPHQRPSADTQGCS*HHSASAFSR KS*GCLGGPGRPEKGSLKF*KENLPPDRISTPE LVRTYGPNSD*GGHPTRDVRKGLLQRKCPPTRH LQPGVCHTAAFPKHSMDFKNVFIFVSQPLYNVFF NLFCNVLF*SIAAILVILPTVFITDLFCESCTL MFYVKIKSI**NTSSI*CGYGTSWKHKTNSDCT AGWAQEVRFILLHMQ*THDF

Frame 2

QRRKRRGRRASGSEVVEAAEAAAEAAAARDWAR LEAARVRAPQQAPISRLDHPPAARTPGPRSLCP GSDPGAQPGAVTLRRRRRGRAGPGWGAVALDPR LPDRWREMSNPGTRRNGSSIKIRLTVLCAKNLAK KDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDP KWNQHYDLYVGKTDSITISVWNHKKIHKKQGAG FLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTD AVRGQIVVSLQTRDRIGTGGSVVDCRGLLENEG TVYEDSGPGRPLSCFMEEPAPYTDSTGAAAGGG NCRFVESPSQDQRLQAQRLRNPDVRGSLQTPQNR PHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVS TWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVS GRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPS QPLPLPSEGSLEDEELPAQRYERDLVQKLKVLR HELSLQQPQAGHCRIEVSREEIFEESYRQIMKM RPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCH EMLNPYYGLFQYSTDNIYMLQINPDSSINPDHL SYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLL GKPIQLSDLESVDPELHKSLVWILENDITPVLDH TFCVEHNAFGRILQHELKPNGRNVPVTEENKKE YVRLYVNWRFMRGIEAQFLALQKGFNELIPQHL LKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCV ADSNIVRWFWQAVETFDEERRARLLQFVTGSTR VPLQGFKALQGSTGAAGPRLFTIHLIDANTDNL PKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCG FAVE*KATKGNRV*LMATRPKASSFCAPPAKLA EALEFQIT*GERVVSLLSVGGGGWGTFVGGSHP YIPPLP*YSHPLPSPIQ*NAARFSLWLWSHRIFC CVATHVVIRLTALSSLREHQLTVRGLGVAD*GF GTGGYASYSISKQP*GPFSI*AAARYLIRAQIP DFTSQQPVLGSRSISNWKITI*CMLIGILPQQEA *VKMCFPFERRRNWSSFSWRPRIFLFWVSWLKI LFYIEKNDLLRVPFAALSVQFDFFFSENTMSWS VGKSRPKSALEPTSQSQSCDLCATVVHRRASTVS LKILVNHDAATAKS*TNKIVSS*LLAWCELA*K QW*KDNLDDVNPPKDTVLQKVGCGRKPVTAEGD DFTLTASCGPFPSGSW*H*RLLLGSLAQMSSYDE QGQKQG*IRSF*HHFQFAQKSVFYLKVA*FPIA ELGQKTAGQCSYVVSLLLFLFGVGASTG*FMSK TFHCCRSLWDPAVGLRWPGKDLVDNGFICSFCHC *FLGC*GSRIEGLPNEVCCRRKV*SPIPKVQAK WWA*PL*KVLPCPHRWAHPVSHSP*CFLRVF*K PVPQWLYPAFPCIIFLLKVRK*KLQTSPGQPTLY HEPNPREAEETSIRELKRPPG*GQRPHLIFLVV VSKIFSN*EGNQGLMV*KTLKQECCI*RL*NYL FAVGRSRGRALAAAPPSPCWLVLPCLSCRVLLQP RARGLGPGSSTGDPGGHTRSHPGLRLCFSTSTC VWVCRLVIGCVSVADLSRAPVHSFQTGLPVGGT ALLEPSVSTMVCLVLLNHPKELNMAKQMVKASRL FYFGSARSPLTCDLCCPSRWSQAIQPCPLPLCP DASGARLFRLALTSGRQPTLRDVANTTPPVLSV GRAEAAWEARGDRKRALSSSEKRICHQIEFRPLS LFGRMVQIQIKVVTQPEMSGKAFCRENVPPPAI CSQVCATRQPSRNIVWILKMCLFLFLNHFITYF LIYFVMSCFEVLLLSLLSFPLFLSLIYFVKVVH* CSMSKSKVFNEILVLFNVVMEPAGNTKQTVIVQ QAGPRRSGSFCYICNKLTT

Sequence NM_020429

GGCAGCGGCGGAAGCGGCGAGGGCGGCGGGCGTCCGGCTCTGAGGTGGTGGAGGCGGCGGAGGCGGCGGCGGAGGCGGCGGCGGCTCGGGACTGGGCTCG GCTGGAAGCAGCGAGGGTCAGAGCGCCGCAGCAAGCGCCGATCTCCCGGCTCGACCATCCGCCTGCCGCCCGGACGCCTGGGCCGCGGAGTTTGTGTCCC GGCTCGGACCCCGGCGCCCAGCCCGGAGCCGTAACCTTGAGGCGGCGGCGGCGGGGCCGGGCCGGGCCGGGCTGGGGGGCGGTGGCGCTGGATCCGCGGC TGCCCGATCGTTGGCGGGAGATGTCGAACCCCGGGACACGCAGGAACGGCTCCAGCATCAAGATCCGTCTGACAGTGTTATGTGCCAAGAACCTTGCAAA GAAAGACTTCTTCAGGCTCCCTGACCCTTTTGCAAAGATTGTCGTGGATGGGTCTGGGCAGTGCCACTCAACCGACACTGTGAAAAACACATTGGACCCA AAGTGGAACCAGCACTATGATCTATATGTTGGGAAAACGGATTCGATAACCATTAGCGTGTGGAACCATAAGAAAATTCACAAGAAACAGGGAGCTGGCT TCCTGGGCTGTGTGCGGCTGCTCTCCAATGCCATCAGCAGATTAAAAGATACCGGATACCAGCGTTTGGATCTATGCAAACTAAACCCCTCAGATACTGA TGCAGTTCGTGGCCAGATAGTGGTCAGTTTACAGACACGAGACAGAATAGGAACCGGCGGCTCGGTGGTGGACTGCAGAGGACTGTTAGAAAATGAAGGA ACGGTGTATGAAGACTCCGGGCCTGGGAGGCCGCTCAGCTGCTTCATGGAGGAACCAGCCCCTTACACAGATAGCACCGGTGCTGCTGCTGGAGGAGGGA ATTGCAGGTTCGTGGAGTCCCCAAGTCAAGATCAAAGACTTCAGGCACAGCGGCTTCGAAACCCTGATGTGCGAGGTTCACTACAGACGCCCCAGAACCG ACCACACGGCCACCAGTCCCCGGAACTGCCCGAAGGCTACGAACAAAGAACAACAGTCCAGGGCCAAGTTTACTTTTTGCATACACAGACTGGAGTTAGC ACGTGGCACGACCCCAGGATACCAAGTCCCTCGGGGACCATTCCTGGGGGAGATGCAGCTTTTCTATACGAATTCCTTCTACAAGGCCATACATCTGAGC CCAGAGACCTTAACAGTGTGAACTGTGATGAACTTGGACCACTGCCGCCAGGCTGGGAAGTCAGAAGTACAGTTTCTGGGAGGATATATTTTGTAGATCA TAATAACCGAACAACCCAGTTTACAGACCCAAGGTTACACCACATCATGAATCACCAGTGCCAACTCAAGGAGCCCAGCCAGCCGCTGCCACTGCCCAGT GAGGGCTCTCTGGAGGACGAGGAGCTTCCTGCCCAGAGATACGAAAGAGATCTAGTCCAGAAGCTGAAAGTCCTCAGACACGAACTGTCGCTTCAGCAGC CCCAAGCTGGTCATTGCCGCATCGAAGTGTCCAGAGAAGAAATCTTTGAGGAGTCTTACCGCCAGATAATGAAGATGCGACCGAAAGACTTGAAAAAACG GCTGATGGTGAAATTCCGTGGGGAAGAAGGTTTGGATTACGGTGGTGTGGCCAGGGAGTGGCTTTACTTGCTGTGCCATGAAATGCTGAATCCTTATTAC GGGCTCTTCCAGTATTCTACGGACAATATTTACATGTTGCAAATAAATCCGGATTCTTCAATCAACCCCGACCACTTGTCTTATTTCCACTTTGTGGGGC GGATCATGGGGCTGGCTGTGTTCCATGGACACTACATCAACGGGGGCTTCACAGTGCCCTTCTACAAGCAGCTGCTGGGGAAGCCCATCCAGCTCTCAGA TCTGGAATCTGTGGACCCAGAGCTGCATAAGAGCTTGGTGTGGATCCTAGAGAACGACATCACGCCTGTACTGGACCACACCTTCTGCGTGGAACACAAC GCCTTCGGGCGGATCCTGCAGCATGAACTGAAACCCAATGGCAGAAATGTGCCAGTCACAGAGGAGAATAAGAAAGAATACGTCCGGTTGTATGTAAACT GGAGGTTTATGAGAGGAATCGAAGCCCAGTTCTTAGCTCTGCAGAAGGGGTTCAATGAGCTCATCCCTCAACATCTGCTGAAGCCTTTTGACCAGAAGGA ACTGGAGCTGATCATAGGCGGCCTGGATAAAATAGACTTGAACGACTGGAAGTCGAACACGCGGCTGAAGCACTGTGTGGCCGACAGCAACATCGTGCGG TGGTTCTGGCAAGCGGTGGAGACGTTCGATGAAGAAAGGAGGGCCAGGCTCCTGCAGTTTGTGACTGGGTCCACGCGAGTCCCGCTCCAAGGCTTCAAGG CTTTGCAAGGTTCTACAGGCGCGGCAGGGCCCCGGCTGTTCACCATCCACCTGATAGACGCGAACACAGACAACCTTCCGAAGGCCCATACCTGCTTTAA CCGGATCGACATTCCACCATATGAGTCCTATGAGAAGCTCTACGAGAAGCTGCTGACAGCCGTGGAGGAGACCTGCGGGTTTGCTGTGGAGTGAAAAGCA ACCAAAGGCAACAGAGTCTAGCTCATGGCCACCAGACCAAAAGCATCCAGCTTCTGTGCACCTCCTGCAAAGCTGGCAGAGGCCCTGGAATTCCAGATCA CCTGAGGGGAAAGGGTTGTCTCTCTCCTTTCTGTTGGGGGAGGGGGATGGGGGACTTTTGTTGGTGGCTCCCACCCATATATCCCTCCTTTACCATAGTA CTCCCACCCACTTCCATCACCCATCCAATAAAATGCAGCCAGGTTTAGCCTTTGGCTTTGGTCACACAGGATATTCTGCTGTGTTGCAACCCATGTGGTG ATAAGGCTCACAGCCCTGAGCTCTTTACGGGAGCATCAACTCACAGTTAGGGGACTGGGCGTGGCTGATTGAGGGTTTGGAACTGGTGGCTATGCCAGCT ATTCCATCTCAAAACAGCCTTGAGGCCCCTTTTCAATTTGAGCAGCTGCTAGATATCTTATCAGAGCTCAGATTCCAGATTTCACATCCCAGCAGCCGGT TCTGGGTAGCAGATCAATTTCCAACTGGAAAATAACTATATAATGTATGCTTATTGGAATTCTGCCACAGCAGGAAGCTTGAGTCAAAATGTGTTTCCCC TTTGAAAGGAGAAGGAATTGGAGCAGCTTTTCCTGGAGGCCCAGGATATTTCTTTTCTGGGTATCTTGGCTGAAAATTTTGTTTTACATAGAGAAAAACG ATCTTTTAAGGGTCCCTTTTGCTGCATTATCTGTCCAGTTTGACTTTTTTTTCAGTGAAAACACCATGTCATGGAGTGTAGGAAAGAGCAGACCAAAATC AGCCCTAGAGCCAACCAGTCAGTCCCAAAGCTGTGACCTCTGTGCCACTGTTGTCCATAGAAGAGCATCGACTGTGTCACTTAAAATATTAGTAAACCAT GATGCAGCAACTGCTAAGAGCTAAACTAACAAAATTGTGTCATCATAGCTGCTGGCTTGGTGTGAACTCGCTTAAAAGCAATGGTGAAAGGATAACCTCG ATGATGTAAATCCACCCAAAGATACTGTTCTACAAAAAGTAGGGTGTGGACGCAAACCTGTGACAGCAGAGGGGGACGACTTCACACTCACTGCCTCATG TGGCCCCTTTCCCAGTGGCAGCTGGTGACACTAACGATTGCTACTCGGTTCACTTGCCCAGATGTCTTCATATGATGAGCAAGGCCAGAAGCAAGGCTAG ATTCGAAGTTTCTGACACCATTTCCAGTTTGCACAAAAGTCAGTATTTTATCTTAAAGTGGCTTGATTTCCAATAGCTGAACTTGGGCAGAAAACAGCAG GCCAATGTTCCTATGTGGTTTCTTTGTTGTTGTTTTTGTTTGGGGTGGGGGCAAGTACAGGGTAATTCATGAGCAAGACATTTCACTGCTGTCGAAGTCT CTGGGATCCCGCTGTGGGTCTGAGATGGCCTGGGAAGGACCTTGTGGACAATGGTTTTATCTGTTCTTTTTGTCACTGTTAATTTCTGGGCTGCTGAGGT TCTAGAATAGAAGGGCTGCCAAATGAGGTTTGCTGCAGGAGGAAAGTTTAATCCCCCATTCCAAAAGTCCAGGCCAAATGGTGGGCTTAGCCTCTTTGAA AAGTTCTGCCTTGCCCCCACAGGTGGGCACATCCTGTGTCTCATTCACCATGATGCTTCCTGAGGGTGTTCTAGAAGCCCGTTCCCCAGTGGCTGTATCC AGCCTTTCCTTGCATCATCTTCCTCTTGAAGGTGAGGAAGTGAAAACTACAGACCTCCCCCGGACAGCCCACTCTCTATCACGAGCCTAACCCGCGGGAG GCGGAAGAGACATCCATTCGAGAACTGAAGCGGCCTCCGGGATGAGGTCAGAGGCCCCACCTGATTTTCCTGGTGGTGGTATCCAAAATCTTCAGTAACT AGGAAGGAAACCAGGGTCTCATGGTTTAAAAGACTTTGAAGCAGGAATGTTGCATTTGACGCCTTTAAAACTACCTTTTTGCTGTTGGGAGGAGTCGGGG GCGAGCCTTAGCAGCTGCACCGCCATCCCCATGCTGGTTGGTGCTGCCCTGCCTCTCGTGCCGGGTGTTGCTTCAGCCCAGAGCCAGAGGGCTGGGTCCC GGGTCCTCCACAGGTGACCCCGGTGGACACACGCGTTCCCATCCTGGCCTCCGTCTCTGCTTTTCCACTTCTACCTGCGTGTGGGTTTGCCGCCTTGTCA TCGGTTGTGTGAGTGTCGCAGACCTTTCCAGAGCTCCGGTTCACTCTTTCCAAACAGGCCTCCCTGTCGGTGGCACTGCACTCCTAGAACCTTCAGTTTC TACGATGGTTTGTTTGGTCCTTTTGAACCACCCCAAAGAACTCAACATGGCAAAGCAAATGGTAAAAGCTTCCCGACTGTTCTACTTTGGGTCCGCGCGA AGCCCACTCACGTGTGATCTGTGTTGCCCCTCTCGGTGGTCCCAGGCGATCCAGCCATGCCCCCTGCCCCTCTGCCCAGATGCTTCAGGGGCCCGGCTTT TCAGGCTTGCCCTCACCAGCGGCCGTCAGCCGACACTCAGGGATGTAGCTAACACCACTCCGCCAGTGCTTTCAGTAGGAAGAGCTGAGGCTGCCTGGGA GGCCCGGGGCGACCGGAAAAGGGCTCTCTCAAGTTCTGAAAAGAGAATCTGCCACCAGATCGAATTTCGACCCCTGAGCTTGTTCGGACGTATGGTCCAA ATTCAGATTAAGGTGGTCACCCAACCCGAGATGTCAGGAAAGGCCTTCTGCAGAGAAAATGTCCCCCCACCCGCCATCTGCAGCCAGGTGTGTGCCACAC GGCAGCCTTCCCGAAACATAGTATGGATTTTAAAAATGTGTTTATTTTTGTTTCTCAACCACTTTATAACGTATTTTTTAATTTATTTTGTAATGTCTTG TTTTGAAGTATTGCTGCTATCCTTGTTATCCTTCCCACTGTTTTTATCACTGATTTATTTTGTGAAAGTTGTACACTAATGTTCTATGTCAAAATCAAAA GTATTTAATGAAATACTAGTTCTATTTAATGTGGTTATGGAACCAGCTGGAAACACAAAACAAACAGTGATTGTACAGCAGGCTGGGCCCAGGAGGTCAG GTTCATTTTGTTACATATGCAATAAACTCACGACTTT

refseq_SMURF1.F2 (forward primer)
refseq_SMURF1.R2 (reverse primer)
Single exon skipping

Frame 0

GSGGSGEGGGRPALRWWRRRRRRRRRRRLGTGL GWKQRGSERRSKRRSPGSTIRLPPGRLGRGVCVP ARTPAPSPEP*P*GGGGGAGPGRAGGRWRWIRG CPIVGGRCRTPGHAGTAPASRSV*QCYVPRTLQ RKTSSGSLTLLQRLSWMGLGSATQPTL*KTHWTQ SGTSTMIYMLGKRIR*PLACGTIRKFTRNRELA SWAVCGCSPMPSAD*KIPDTSVWIYAN*TPQIL MQFVAR*WSVYRHETE*EPAARWWTAEDC*KMKE RCMKTPGLGGRSAASWRNQPLTQIAPVLLLEEG IAGSWSPQVKIKDFRHSGFETLMCEVHYRRPRT DHTATSPRNCPKATNKEQQSRAKFTFCIHRLELA RGTTPGYQVPRGPFLGEMQLFYTNSFYKAIHLS PETLTV*TVMNLDHCRQAGKSEVQFLGGYIL*I IITEQPSLQTQGYTTS*ITSANSRSPASRCHCPV RALWRTRSFLPRDTKEI*SRS*KSSDTNCRFSS PKLVIAASKCPEKKSLRSLTAR**RCDRKT*KN G*W*NSVGKKVWITVVWPGSGFTCCAMKC*ILIT GSSSILRTIFTCCK*IRILQSTPTTCLISTLWG GSWGWLCSMDTTSTGASQCPSTSSCWGSPSSSQ IWNLWTQSCIRAWCGS*RTTSRLYWTTPSAWNTT PSGGSCSMN*NPMAEMCQSQRRIRKNTSGCM*T GGL*EESKPSS*LCRRGSMSSSLNIC*SLLTRR NWS*S*AAWIK*T*TTGSRTRG*STVWPTATSCG GSGKRWRRSMKKGGPGSCSL*LGPRESRSKASR LCKVLQARQGPGCSPST**TRTQTTFRRPIPAL TGSTFHHMSPMRSSTRSC*QPWRRPAGLLWSEKQ PKATESSSWPPDQKHPASVHLLQSWQRPWNSRS PEGKGLSLSFLLGEGDGGLLLVAPTHISLLYHS TPTHFHHPSNKMQPGLAFGFGHTGYSAVLQPMW* *GSQP*ALYGSINSQLGDWAWLIEGLELVAMPA IPSQNSLEAPFQFEQLLDILSELRFQISHPSSR FWVADQFPTGK*LYNVCLLEFCHSRKLESKCVSP LKGEGIGAAFPGGPGYFFSGYLG*KFCFT*RKT IF*GSLLLHYLSSLTFFSVKTPCHGV*ERADQN QP*SQPVSPKAVTSVPLLSIEEHRLCHLKY**TM MQQLLRAKLTKLCHHSCWLGVNSLKSNGERITS MM*IHPKILFYKK*GVDANL*QQRGTTSHSLPH VAPFPVAAGDTNDCYSVHLPRCLHMMSKARSKAR FEVSDTISSLHKSQYFILKWLDFQ*LNLGRKQQ ANVPMWFLCCCFCLGWGQVQGNS*ARHFTAVEV SGIPLWV*DGLGRTLWTMVLSVLFVTVNFWAAEV LE*KGCQMRFAAGGKFNPPFQKSRPNGGLSLFE KFCLAPTGGHILCLIHHDAS*GCSRSPFPSGCI QPFLASSSS*R*GSENYRPPPDSPLSITSLTRGR RKRHPFEN*SGLRDEVRGPT*FSWWWYPKSSVT RKETRVSWFKRL*SRNVAFDAFKTTFLLLGGVG GEP*QLHRHPHAGWCCPASRAGCCFSPEPEGWVP GPPQVTPVDTRVPILASVSAFPLLPACGFAALS SVV*VSQTFPELRFTLSKQASLSVALHS*NLQF LRWFVWSF*TTPKNSTWQSKW*KLPDCSTLGPRE AHSRVICVAPLGGPRRSSHAPCPSAQMLQGPGF SGLPSPAAVSRHSGM*LTPLRQCFQ*EELRLPG RPGATGKGLSQVLKRESATRSNFDP*ACSDVWSK FRLRWSPNPRCQERPSAEKMSPHPPSAARCVPH GSLPET*YGF*KCVYFCFSTTL*RIF*FIL*CL VLKYCCYPCYPSHCFYH*FIL*KLYTNVLCQNQK YLMKY*FYLMWLWNQLETQNKQ*LYSRLGPGGQ VHFVTYAINSRL

Frame 1

AAAEAARAAGVRL*GGGGGGGGGGGGGGSGLGS AGSSEGQSAAASADLPARPSACRPDAWAAEFVS RLGPRRPARSRNLEAAAAGPGRAGLGGGGAGSAA ARSLAGDVEPRDTQERLQHQDPSDSVMCQEPCK ERLLQAP*PFCKDCRGWVWAVPLNRHCEKHIGP KVEPAL*SICWENGFDNH*RVEP*ENSQETGSWL PGLCAAALQCHQQIKRYRIPAFGSMQTKPLRY* CSSWPDSGQFTDTRQNRNRRLGGGLQRTVRK*R NGV*RLRAWEAAQLLHGGTSPLHR*HRCCCWRRE LQVRGVPKSRSKTSGTAASKP*CARFTTDAPEP TTRPPVPGTARRLRTKNNSPGPSLLFAYTDWS* HVARPQDTKSLGDHSWGRCSFSIRIPSTRPYI*A QRP*QCEL**TWTTAARLGSQKYSFWEDIFCRS **PNNPVYRPKVTPHHESPVPTQGAQPAAATAQ *GLSGGRGASCPEIRKRSSPEAESPQTRTVASAA PSWSLPHRSVQRRNL*GVLPPDNEDATERLEKT ADGEIPWGRRFGLRWCGQGVALLAVP*NAESLL RALPVFYGQYLHVANKSGFFNQPRPLVLFPLCGA DHGAGCVPWTLHQRGLHSALLQAAAGEAHPALR SGICGPRAA*ELGVDPRERHHACTGPHLLRGTQ RLRADPAA*TETQWQKCASHRGE*ERIRPVVCKL EVYERNRSPVLSSAEGVQ*AHPSTSAEAF*PEG TGADHRRPG*NRLERLEVEHAAEALCGRQQHRA VVLASGGDVR*RKEGQAPAVCDWVHASPAPRLQG FARFYRRGRAPAVHHPPDRREHRQPSEGPYLL* PDRHSTI*VL*EALREAADSRGGDLRVCCGVKS NQRQQSLAHGHQTKSIQLLCTSCKAGRGPGIPDH LRGKGCLSPFCWGRGMGDFCWWLPPIYPSFTIV LPPTSITHPIKCSQV*PLALVTQDILLCCNPCG DKAHSPELFTGASTHS*GTGRG*LRVWNWWLCQL FHLKTALRPLFNLSSC*ISYQSSDSRFHIPAAG SG*QINFQLENNYIMYAYWNSATAGSLSQNVFP L*KEKELEQLFLEAQDISFLGILAENFVLHREKR SFKGPFCCIICPV*LFFQ*KHHVMECRKEQTKI SPRANQSVPKL*PLCHCCP*KSIDCVT*NISKP *CSNC*ELN*QNCVIIAAGLV*TRLKAMVKG*PR *CKSTQRYCSTKSRVWTQTCDSRGGRLHTHCLM WPLSQWQLVTLTIATRFTCPDVFI**ARPEARL DSKFLTPFPVCTKVSILS*SGLISNS*TWAENSR PMFLCGFFVVVFVWGGGKYRVIHEQDISLLSKS LGSRCGSEMAWEGPCGQWFYLFFLSLLISGLLR F*NRRAAK*GLLQEESLIPHSKSPGQMVGLASLK SSALPPQVGTSCVSFTMMLPEGVLEARSPVAVS SLSLHHLPLEGEEVKTTDLPRTAHSLSRA*PAG GGRDIHSRTEAASGMRSEAPPDFPGGGIQNLQ*L GRKPGSHGLKDFEAGMLHLTPLKLPFCCWEESG ASLSSCTAIPMLVGAALPLVPGVASAQSQRAGS RVLHR*PRWTHAFPSWPPSLLFHFYLRVGLPPCH RLCECRRPFQSSGSLFPNRPPCRWHCTPRTFSF YDGLFGPFEPPQRTQHGKANGKSFPTVLLWVRA KPTHV*SVLPLSVVPGDPAMPPAPLPRCFRGPAF QACPHQRPSADTQGCS*HHSASAFSRKS*GCLG GPGRPEKGSLKF*KENLPPDRISTPELVRTYGP NSD*GGHPTRDVRKGLLQRKCPPTRHLQPGVCHT AAFPKHSMDFKNVFIFVSQPLYNVFFNLFCNVL F*SIAAILVILPTVFITDLFCESCTLMFYVKIK SI**NTSSI*CGYGTSWKHKTNSDCTAGWAQEVR FILLHMQ*THDF

Frame 2

QRRKRRGRRASGSEVVEAAEAAAEAAAARDWAR LEAARVRAPQQAPISRLDHPPAARTPGPRSLCP GSDPGAQPGAVTLRRRRRGRAGPGWGAVALDPR LPDRWREMSNPGTRRNGSSIKIRLTVLCAKNLAK KDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDP KWNQHYDLYVGKTDSITISVWNHKKIHKKQGAG FLGCVRLLSNAISRLKDTGYQRLDLCKLNPSDTD AVRGQIVVSLQTRDRIGTGGSVVDCRGLLENEG TVYEDSGPGRPLSCFMEEPAPYTDSTGAAAGGG NCRFVESPSQDQRLQAQRLRNPDVRGSLQTPQNR PHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVS TWHDPRIPSPSGTIPGGDAAFLYEFLLQGHTSE PRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDH NNRTTQFTDPRLHHIMNHQCQLKEPSQPLPLPS EGSLEDEELPAQRYERDLVQKLKVLRHELSLQQ PQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKR LMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYY GLFQYSTDNIYMLQINPDSSINPDHLSYFHFVG RIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSD LESVDPELHKSLVWILENDITPVLDHTFCVEHN AFGRILQHELKPNGRNVPVTEENKKEYVRLYVN WRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKE LELIIGGLDKIDLNDWKSNTRLKHCVADSNIVR WFWQAVETFDEERRARLLQFVTGSTRVPLQGFK ALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFN RIDIPPYESYEKLYEKLLTAVEETCGFAVE*KA TKGNRV*LMATRPKASSFCAPPAKLAEALEFQI T*GERVVSLLSVGGGGWGTFVGGSHPYIPPLP*Y SHPLPSPIQ*NAARFSLWLWSHRIFCCVATHVV IRLTALSSLREHQLTVRGLGVAD*GFGTGGYAS YSISKQP*GPFSI*AAARYLIRAQIPDFTSQQPV LGSRSISNWKITI*CMLIGILPQQEA*VKMCFP FERRRNWSSFSWRPRIFLFWVSWLKILFYIEKN DLLRVPFAALSVQFDFFFSENTMSWSVGKSRPKS ALEPTSQSQSCDLCATVVHRRASTVSLKILVNH DAATAKS*TNKIVSS*LLAWCELA*KQW*KDNL DDVNPPKDTVLQKVGCGRKPVTAEGDDFTLTASC GPFPSGSW*H*RLLLGSLAQMSSYDEQGQKQG* IRSF*HHFQFAQKSVFYLKVA*FPIAELGQKTA GQCSYVVSLLLFLFGVGASTG*FMSKTFHCCRSL WDPAVGLRWPGKDLVDNGFICSFCHC*FLGC*G SRIEGLPNEVCCRRKV*SPIPKVQAKWWA*PL* KVLPCPHRWAHPVSHSP*CFLRVF*KPVPQWLYP AFPCIIFLLKVRK*KLQTSPGQPTLYHEPNPRE AEETSIRELKRPPG*GQRPHLIFLVVVSKIFSN *EGNQGLMV*KTLKQECCI*RL*NYLFAVGRSRG RALAAAPPSPCWLVLPCLSCRVLLQPRARGLGP GSSTGDPGGHTRSHPGLRLCFSTSTCVWVCRLV IGCVSVADLSRAPVHSFQTGLPVGGTALLEPSVS TMVCLVLLNHPKELNMAKQMVKASRLFYFGSAR SPLTCDLCCPSRWSQAIQPCPLPLCPDASGARL FRLALTSGRQPTLRDVANTTPPVLSVGRAEAAWE ARGDRKRALSSSEKRICHQIEFRPLSLFGRMVQ IQIKVVTQPEMSGKAFCRENVPPPAICSQVCAT RQPSRNIVWILKMCLFLFLNHFITYFLIYFVMSC FEVLLLSLLSFPLFLSLIYFVKVVH*CSMSKSK VFNEILVLFNVVMEPAGNTKQTVIVQQAGPRRS GSFCYICNKLTT