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Sequences

Sequence NM_175840

GGGACGCGAGGCGGAGCGGGGCCCCACACAGGCCGCGGCGGCTGGCTCGGGCCCCTACGGTCCCGGCGGCGGCTGGAGGAGGAAGCCAGGCGGCTGGCGG AGGAGGAGAGACGGAGGAGGCCGAGACCGGAGCGCCGCTCGCCGCAGACTTACTTCCCCGGCTCAGCAGGGAAAGGTTCCTAGAAGGTGAGCGCGGACGG TATGCAAAGTTGTGAATCCAGTGGTGACAGTGCGGATGACCCTCTCAGTCGCGGCCTACGGAGAAGGGGACAGCCTCGTGTGGTGGTGATCGGCGCCGGC TTGGCTGGCCTGGCTGCAGCCAAAGCACTTCTTGAGCAGGGTTTCACGGATGTCACTGTGCTTGAGGCTTCCAGCCACATCGGAGGCCGTGTGCAGAGTG TGAAACTTGGACACGCCACCTTTGAGCTGGGAGCCACCTGGATCCATGGCTCCCATGGGAACCCTATCTATCATCTAGCAGAAGCCAACGGCCTCCTGGA AGAGACAACCGATGGGGAACGCAGCGTGGGCCGCATCAGCCTCTATTCCAAGAATGGCGTGGCCTGCTACCTTACCAACCACGGCCGCAGGATCCCCAAG GACGTGGTTGAGGAATTCAGCGATTTATACAACGAGGTCTATAACTTGACCCAGGAGTTCTTCCGGCACGATAAACCAGTCAATGCTGAAAGTCAAAATA GCGTGGGGGTGTTCACCCGAGAGGAGGTGCGTAACCGCATCAGGAATGACCCTGACGACCCAGAGGCTACCAAGCGCCTGAAGCTCGCCATGATCCAGCA GTACCTGAAGGTGGAGAGCTGTGAGAGCAGCTCACACAGCATGGACGAGGTGTCCCTGAGCGCCTTCGGGGAGTGGACCGAGATCCCCGGCGCTCACCAC ATCATCCCCTCGGGCTTCATGCGGGTTGTGGAGCTGCTGGCGGAGGGCATCCCTGCCCACGTCATCCAGCTAGGGAAACCTGTCCGCTGCATTCACTGGG ACCAGGCCTCAGCCCGCCCCAGAGGCCCTGAGATTGAGCCCCGGGGTGTGCTAAAGAGGCAGTACACCAGTTTCTTCCGGCCAGGCCTGCCCACAGAGAA GGTGGCTGCCATCCACCGCCTGGGCATTGGCACCACCGACAAGATCTTTCTGGAATTCGAGGAGCCCTTCTGGGGCCCTGAGTGCAACAGCCTACAGTTT GTGTGGGAGGACGAAGCAGAGAGCCACACCCTCACCTACCCACCTGAGCTCTGGTACCGCAAGATCTGCGGCTTTGATGTCCTCTACCCGCCTGAGCGCT ACGGCCATGTGCTGAGCGGCTGGATCTGCGGGGAGGAGGCCCTCGTCATGGAGAAGTGTGATGACGAGGCAGTGGCCGAGATCTGCACGGAGATGCTGCG TCAGTTCACAGGGAACCCCAACATTCCAAAACCTCGGCGAATCTTGCGCTCGGCCTGGGGCAGCAACCCTTACTTCCGCGGCTCCTATTCATACACGCAG GTGGGCTCCAGCGGGGCGGATGTGGAGAAGCTGGCCAAGCCCCTGCCGTACACAGAGAGCTCAAAGACAGCGCCCATGCAGGTGCTGTTTTCCGGTGAGG CCACCCACCGCAAGTACTATTCCACCACCCACGGTGCTCTGCTGTCCGGCCAGCGTGAGGCTGCCCGCCTCATTGAGATGTACCGAGACCTCTTCCAGCA GGGGACCTGAGGGCTGTCCTCGCTGCTGAGAAGAGCCACTAACTCGTGACCTCCAGCCTGCCCCTTGCTGCCGTGTGCTCCTGCCTTCCTGATCCTCTGT AGAAAGGATTTTTATCTTCTGTAGAGCTAGCCGCCCTGACTGCCTTCAGACCTGGCCCTGTAGCTTTTCTTTTTCTCCAGGCTGGGCCGTGAGCAGGTGG GCCGTTGAGTTACCTCTGTGCTGGATCCCGTGCCCCCACTTGCCTACCCTCTGTCCTGCCTTGTTATTGTAAGTGCCTTCAATACTTTGCATTTTGGGAT AATAAAAAAGGCTCCCTCCCCTGCC

refseq_SMOX.F1 (forward primer)
refseq_SMOX.R1 (reverse primer)
Single exon skipping

Frame 0

GTRGGAGPHTGRGGWLGPLRSRRRLEEEARRLA EEERRRRPRPERRSPQTYFPGSAGKGS*KVSADG MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAG LAGLAAAKALLEQGFTDVTVLEASSHIGGRVQS VKLGHATFELGATWIHGSHGNPIYHLAEANGLLE ETTDGERSVGRISLYSKNGVACYLTNHGRRIPK DVVEEFSDLYNEVYNLTQEFFRHDKPVNAESQN SVGVFTREEVRNRIRNDPDDPEATKRLKLAMIQQ YLKVESCESSSHSMDEVSLSAFGEWTEIPGAHH IIPSGFMRVVELLAEGIPAHVIQLGKPVRCIHW DQASARPRGPEIEPRGVLKRQYTSFFRPGLPTEK VAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQF VWEDEAESHTLTYPPELWYRKICGFDVLYPPER YGHVLSGWICGEEALVMEKCDDEAVAEICTEMLR QFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQ VGSSGADVEKLAKPLPYTESSKTAPMQVLFSGE ATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQ GT*GLSSLLRRATNS*PPACPLLPCAPAFLILC RKDFYLL*S*PP*LPSDLAL*LFFFSRLGREQV GR*VTSVLDPVPPLAYPLSCLVIVSAFNTLHFGI IKKAPSPA

Frame 1

GREAERGPTQAAAAGSGPYGPGGGWRRKPGGWR RRRDGGGRDRSAARRRLTSPAQQGKVPRR*ART VCKVVNPVVTVRMTLSVAAYGEGDSLVWW*SAPA WLAWLQPKHFLSRVSRMSLCLRLPATSEAVCRV *NLDTPPLSWEPPGSMAPMGTLSII*QKPTASW KRQPMGNAAWAASASIPRMAWPATLPTTAAGSPR TWLRNSAIYTTRSIT*PRSSSGTINQSMLKVKI AWGCSPERRCVTASGMTLTTQRLPSA*SSP*SS ST*RWRAVRAAHTAWTRCP*APSGSGPRSPALTT SSPRASCGLWSCWRRASLPTSSS*GNLSAAFTG TRPQPAPEALRLSPGVC*RGSTPVSSGQACPQR RWLPSTAWALAPPTRSFWNSRSPSGALSATAYSL CGRTKQRATPSPTHLSSGTARSAALMSSTRLSA TAMC*AAGSAGRRPSSWRSVMTRQWPRSARRCC VSSQGTPTFQNLGESCARPGAATLTSAAPIHTRR WAPAGRMWRSWPSPCRTQRAQRQRPCRCCFPVR PPTASTIPPPTVLCCPASVRLPASLRCTETSSS RGPEGCPRC*EEPLTRDLQPAPCCRVLLPS*SSV ERIFIFCRASRPDCLQTWPCSFSFSPGWAVSRW AVELPLCWIPCPHLPTLCPALLL*VPSILCILG **KRLPPL

Frame 2

DARRSGAPHRPRRLARAPTVPAAAGGGSQAAGG GGETEEAETGAPLAADLLPRLSRERFLEGERGR YAKL*IQW*QCG*PSQSRPTEKGTASCGGDRRR LGWPGCSQSTS*AGFHGCHCA*GFQPHRRPCAEC ETWTRHL*AGSHLDPWLPWEPYLSSSRSQRPPG RDNRWGTQRGPHQPLFQEWRGLLPYQPRPQDPQ GRG*GIQRFIQRGL*LDPGVLPAR*TSQC*KSK* RGGVHPRGGA*PHQE*P*RPRGYQAPEARHDPA VPEGGEL*EQLTQHGRGVPERLRGVDRDPRRSP HHPLGLHAGCGAAGGGHPCPRHPARETCPLHSLG PGLSPPQRP*D*APGCAKEAVHQFLPARPAHRE GGCHPPPGHWHHRQDLSGIRGALLGP*VQQPTV CVGGRSREPHPHLPT*ALVPQDLRL*CPLPA*AL RPCAERLDLRGGGPRHGEV**RGSGRDLHGDAA SVHREPQHSKTSANLALGLGQQPLLPRLLFIHA GGLQRGGCGEAGQAPAVHRELKDSAHAGAVFR*G HPPQVLFHHPRCSAVRPA*GCPPH*DVPRPLPA GDLRAVLAAEKSH*LVTSSLPLAAVCSCLPDPL *KGFLSSVELAALTAFRPGPVAFLFLQAGP*AGG PLSYLCAGSRAPTCLPSVLPCYCKCLQYFAFWD NKKGSLPC

Sequence NM_175839

GGGACGCGAGGCGGAGCGGGGCCCCACACAGGCCGCGGCGGCTGGCTCGGGCCCCTACGGTCCCGGCGGCGGCTGGAGGAGGAAGCCAGGCGGCTGGCGG AGGAGGAGAGACGGAGGAGGCCGAGACCGGAGCGCCGCTCGCCGCAGACTTACTTCCCCGGCTCAGCAGGGAAAGGTTCCTAGAAGGTGAGCGCGGACGG TATGCAAAGTTGTGAATCCAGTGGTGACAGTGCGGATGACCCTCTCAGTCGCGGCCTACGGAGAAGGGGACAGCCTCGTGTGGTGGTGATCGGCGCCGGC TTGGCTGGCCTGGCTGCAGCCAAAGCACTTCTTGAGCAGGGTTTCACGGATGTCACTGTGCTTGAGGCTTCCAGCCACATCGGAGGCCGTGTGCAGAGTG TGAAACTTGGACACGCCACCTTTGAGCTGGGAGCCACCTGGATCCATGGCTCCCATGGGAACCCTATCTATCATCTAGCAGAAGCCAACGGCCTCCTGGA AGAGACAACCGATGGGGAACGCAGCGTGGGCCGCATCAGCCTCTATTCCAAGAATGGCGTGGCCTGCTACCTTACCAACCACGGCCGCAGGATCCCCAAG GACGTGGTTGAGGAATTCAGCGATTTATACAACGAGGTCTATAACTTGACCCAGGAGTTCTTCCGGCACGATAAACCAGTCAATGCTGAAAGTCAAAATA GCGTGGGGGTGTTCACCCGAGAGGAGGTGCGTAACCGCATCAGGAATGACCCTGACGACCCAGAGGCTACCAAGCGCCTGAAGCTCGCCATGATCCAGCA GTACCTGAAGGTGGAGAGCTGTGAGAGCAGCTCACACAGCATGGACGAGGTGTCCCTGAGCGCCTTCGGGGAGTGGACCGAGATCCCCGGCGCTCACCAC ATCATCCCCTCGGGCTTCATGCGGGTTGTGGAGCTGCTGGCGGAGGGCATCCCTGCCCACGTCATCCAGCTAGGGAAACCTGTCCGCTGCATTCACTGGG ACCAGGCCTCAGCCCGCCCCAGAGGCCCTGAGATTGAGCCCCGGGGTGAGGGCGACCACAATCACGACACTGGGGAGGGTGGCCAGGGTGGAGAGGAGCC CCGGGGGGGCAGGTGGGATGAGGATGAGCAGTGGTCGGTGGTGGTGGAGTGCGAGGACTGTGAGCTGATCCCGGCGGACCATGTGATTGTGACCGTGTCG CTAGGTGTGCTAAAGAGGCAGTACACCAGTTTCTTCCGGCCAGGCCTGCCCACAGAGAAGGTGGCTGCCATCCACCGCCTGGGCATTGGCACCACCGACA AGATCTTTCTGGAATTCGAGGAGCCCTTCTGGGGCCCTGAGTGCAACAGCCTACAGTTTGTGTGGGAGGACGAAGCAGAGAGCCACACCCTCACCTACCC ACCTGAGCTCTGGTACCGCAAGATCTGCGGCTTTGATGTCCTCTACCCGCCTGAGCGCTACGGCCATGTGCTGAGCGGCTGGATCTGCGGGGAGGAGGCC CTCGTCATGGAGAAGTGTGATGACGAGGCAGTGGCCGAGATCTGCACGGAGATGCTGCGTCAGTTCACAGGGAACCCCAACATTCCAAAACCTCGGCGAA TCTTGCGCTCGGCCTGGGGCAGCAACCCTTACTTCCGCGGCTCCTATTCATACACGCAGGTGGGCTCCAGCGGGGCGGATGTGGAGAAGCTGGCCAAGCC CCTGCCGTACACAGAGAGCTCAAAGACAGCGCCCATGCAGGTGCTGTTTTCCGGTGAGGCCACCCACCGCAAGTACTATTCCACCACCCACGGTGCTCTG CTGTCCGGCCAGCGTGAGGCTGCCCGCCTCATTGAGATGTACCGAGACCTCTTCCAGCAGGGGACCTGAGGGCTGTCCTCGCTGCTGAGAAGAGCCACTA ACTCGTGACCTCCAGCCTGCCCCTTGCTGCCGTGTGCTCCTGCCTTCCTGATCCTCTGTAGAAAGGATTTTTATCTTCTGTAGAGCTAGCCGCCCTGACT GCCTTCAGACCTGGCCCTGTAGCTTTTCTTTTTCTCCAGGCTGGGCCGTGAGCAGGTGGGCCGTTGAGTTACCTCTGTGCTGGATCCCGTGCCCCCACTT GCCTACCCTCTGTCCTGCCTTGTTATTGTAAGTGCCTTCAATACTTTGCATTTTGGGATAATAAAAAAGGCTCCCTCCCCTGCC

refseq_SMOX.F1 (forward primer)
refseq_SMOX.R1 (reverse primer)
Single exon skipping

Frame 0

GTRGGAGPHTGRGGWLGPLRSRRRLEEEARRLA EEERRRRPRPERRSPQTYFPGSAGKGS*KVSADG MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAG LAGLAAAKALLEQGFTDVTVLEASSHIGGRVQS VKLGHATFELGATWIHGSHGNPIYHLAEANGLLE ETTDGERSVGRISLYSKNGVACYLTNHGRRIPK DVVEEFSDLYNEVYNLTQEFFRHDKPVNAESQN SVGVFTREEVRNRIRNDPDDPEATKRLKLAMIQQ YLKVESCESSSHSMDEVSLSAFGEWTEIPGAHH IIPSGFMRVVELLAEGIPAHVIQLGKPVRCIHW DQASARPRGPEIEPRGEGDHNHDTGEGGQGGEEP RGGRWDEDEQWSVVVECEDCELIPADHVIVTVS LGVLKRQYTSFFRPGLPTEKVAAIHRLGIGTTD KIFLEFEEPFWGPECNSLQFVWEDEAESHTLTYP PELWYRKICGFDVLYPPERYGHVLSGWICGEEA LVMEKCDDEAVAEICTEMLRQFTGNPNIPKPRR ILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKP LPYTESSKTAPMQVLFSGEATHRKYYSTTHGAL LSGQREAARLIEMYRDLFQQGT*GLSSLLRRAT NS*PPACPLLPCAPAFLILCRKDFYLL*S*PP*L PSDLAL*LFFFSRLGREQVGR*VTSVLDPVPPL AYPLSCLVIVSAFNTLHFGIIKKAPSPA

Frame 1

GREAERGPTQAAAAGSGPYGPGGGWRRKPGGWR RRRDGGGRDRSAARRRLTSPAQQGKVPRR*ART VCKVVNPVVTVRMTLSVAAYGEGDSLVWW*SAPA WLAWLQPKHFLSRVSRMSLCLRLPATSEAVCRV *NLDTPPLSWEPPGSMAPMGTLSII*QKPTASW KRQPMGNAAWAASASIPRMAWPATLPTTAAGSPR TWLRNSAIYTTRSIT*PRSSSGTINQSMLKVKI AWGCSPERRCVTASGMTLTTQRLPSA*SSP*SS ST*RWRAVRAAHTAWTRCP*APSGSGPRSPALTT SSPRASCGLWSCWRRASLPTSSS*GNLSAAFTG TRPQPAPEALRLSPGVRATTITTLGRVARVERS PGGAGGMRMSSGRWWWSARTVS*SRRTM*L*PCR *VC*RGSTPVSSGQACPQRRWLPSTAWALAPPT RSFWNSRSPSGALSATAYSLCGRTKQRATPSPT HLSSGTARSAALMSSTRLSATAMC*AAGSAGRRP SSWRSVMTRQWPRSARRCCVSSQGTPTFQNLGE SCARPGAATLTSAAPIHTRRWAPAGRMWRSWPS PCRTQRAQRQRPCRCCFPVRPPTASTIPPPTVLC CPASVRLPASLRCTETSSSRGPEGCPRC*EEPL TRDLQPAPCCRVLLPS*SSVERIFIFCRASRPD CLQTWPCSFSFSPGWAVSRWAVELPLCWIPCPHL PTLCPALLL*VPSILCILG**KRLPPL

Frame 2

DARRSGAPHRPRRLARAPTVPAAAGGGSQAAGG GGETEEAETGAPLAADLLPRLSRERFLEGERGR YAKL*IQW*QCG*PSQSRPTEKGTASCGGDRRR LGWPGCSQSTS*AGFHGCHCA*GFQPHRRPCAEC ETWTRHL*AGSHLDPWLPWEPYLSSSRSQRPPG RDNRWGTQRGPHQPLFQEWRGLLPYQPRPQDPQ GRG*GIQRFIQRGL*LDPGVLPAR*TSQC*KSK* RGGVHPRGGA*PHQE*P*RPRGYQAPEARHDPA VPEGGEL*EQLTQHGRGVPERLRGVDRDPRRSP HHPLGLHAGCGAAGGGHPCPRHPARETCPLHSLG PGLSPPQRP*D*APG*GRPQSRHWGGWPGWRGA PGGQVG*G*AVVGGGGVRGL*ADPGGPCDCDRV ARCAKEAVHQFLPARPAHREGGCHPPPGHWHHRQ DLSGIRGALLGP*VQQPTVCVGGRSREPHPHLP T*ALVPQDLRL*CPLPA*ALRPCAERLDLRGGG PRHGEV**RGSGRDLHGDAASVHREPQHSKTSAN LALGLGQQPLLPRLLFIHAGGLQRGGCGEAGQA PAVHRELKDSAHAGAVFR*GHPPQVLFHHPRCS AVRPA*GCPPH*DVPRPLPAGDLRAVLAAEKSH* LVTSSLPLAAVCSCLPDPL*KGFLSSVELAALT AFRPGPVAFLFLQAGP*AGGPLSYLCAGSRAPT CLPSVLPCYCKCLQYFAFWDNKKGSLPC

Sequence NM_175842

GGGACGCGAGGCGGAGCGGGGCCCCACACAGGCCGCGGCGGCTGGCTCGGGCCCCTACGGTCCCGGCGGCGGCTGGAGGAGGAAGCCAGGCGGCTGGCGG AGGAGGAGAGACGGAGGAGGCCGAGACCGGAGCGCCGCTCGCCGCAGACTTACTTCCCCGGCTCAGCAGGGAAAGGTTCCTAGAAGGTGAGCGCGGACGG TATGCAAAGTTGTGAATCCAGTGGTGACAGTGCGGATGACCCTCTCAGTCGCGGCCTACGGAGAAGGGGACAGCCTCGTGTGGTGGTGATCGGCGCCGGC TTGGCTGGCCTGGCTGCAGCCAAAGCACTTCTTGAGCAGGGTTTCACGGATGTCACTGTGCTTGAGGCTTCCAGCCACATCGGAGGCCGTGTGCAGAGTG TGAAACTTGGACACGCCACCTTTGAGCTGGGAGCCACCTGGATCCATGGCTCCCATGGGAACCCTATCTATCATCTAGCAGAAGCCAACGGCCTCCTGGA AGAGACAACCGATGGGGAACGCAGCGTGGGCCGCATCAGCCTCTATTCCAAGAATGGCGTGGCCTGCTACCTTACCAACCACGGCCGCAGGATCCCCAAG GACGTGGTTGAGGAATTCAGCGATTTATACAACGAGGTCTATAACTTGACCCAGGAGTTCTTCCGGCACGATAAACCAGTCAATGCTGAAAGTCAAAATA GCGTGGGGGTGTTCACCCGAGAGGAGGTGCGTAACCGCATCAGGAATGACCCTGACGACCCAGAGGCTACCAAGCGCCTGAAGCTCGCCATGATCCAGCA GTACCTGAAGGTGGAGAGCTGTGAGAGCAGCTCACACAGCATGGACGAGGTGTCCCTGAGCGCCTTCGGGGAGTGGACCGAGATCCCCGGCGCTCACCAC ATCATCCCCTCGGGCTTCATGCGGGTTGTGGAGCTGCTGGCGGAGGGCATCCCTGCCCACGTCATCCAGCTAGGGAAACCTGTCCGCTGCATTCACTGGG ACCAGGCCTCAGCCCGCCCCAGAGGCCCTGAGATTGAGCCCCGGGGTGTGCTAAAGAGGCAGTACACCAGTTTCTTCCGGCCAGGCCTGCCCACAGAGAA GGTGGCTGCCATCCACCGCCTGGGCATTGGCACCACCGACAAGATCTTTCTGGAATTCGAGGAGCCCTTCTGGGGCCCTGAGTGCAACAGCCTACAGTTT GTGTGGGAGGACGAAGCAGAGAGCCACACCCTCACCTACCCACCTGAGCTCTGGTACCGCAAGATCTGCGGCTTTGATGTCCTCTACCCGCCTGAGCGCT ACGGCCATGTGCTGAGCGGCTGGATCTGCGGGGAGGAGGCCCTCGTCATGGAGAAGTGTGATGACGAGGCAGTGGCCGAGATCTGCACGGAGATGCTGCG TCAGTTCACAGGGAACCCCAACATTCCAAAACCTCGGCGAATCTTGCGCTCGGCCTGGGGCAGCAACCCTTACTTCCGCGGCTCCTATTCATACACGCAG GTGGGCTCCAGCGGGGCGGATGTGGAGAAGCTGGCCAAGCCCCTGCCGTACACAGAGAGCTCAAAGACAGCGCATGGAAGCTCCACAAAGCAGCAGCCTG GTCACCTTTTCTCTTCCAAGTGCCCAGAACAGCCCCTGGATGCTAACAGGGGCGCCGTAAAGCCCATGCAGGTGCTGTTTTCCGGTGAGGCCACCCACCG CAAGTACTATTCCACCACCCACGGTGCTCTGCTGTCCGGCCAGCGTGAGGCTGCCCGCCTCATTGAGATGTACCGAGACCTCTTCCAGCAGGGGACCTGA GGGCTGTCCTCGCTGCTGAGAAGAGCCACTAACTCGTGACCTCCAGCCTGCCCCTTGCTGCCGTGTGCTCCTGCCTTCCTGATCCTCTGTAGAAAGGATT TTTATCTTCTGTAGAGCTAGCCGCCCTGACTGCCTTCAGACCTGGCCCTGTAGCTTTTCTTTTTCTCCAGGCTGGGCCGTGAGCAGGTGGGCCGTTGAGT TACCTCTGTGCTGGATCCCGTGCCCCCACTTGCCTACCCTCTGTCCTGCCTTGTTATTGTAAGTGCCTTCAATACTTTGCATTTTGGGATAATAAAAAAG GCTCCCTCCCCTGCC

refseq_SMOX.F1 (forward primer)
refseq_SMOX.R1 (reverse primer)
Single exon skipping

Frame 0

GTRGGAGPHTGRGGWLGPLRSRRRLEEEARRLA EEERRRRPRPERRSPQTYFPGSAGKGS*KVSADG MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAG LAGLAAAKALLEQGFTDVTVLEASSHIGGRVQS VKLGHATFELGATWIHGSHGNPIYHLAEANGLLE ETTDGERSVGRISLYSKNGVACYLTNHGRRIPK DVVEEFSDLYNEVYNLTQEFFRHDKPVNAESQN SVGVFTREEVRNRIRNDPDDPEATKRLKLAMIQQ YLKVESCESSSHSMDEVSLSAFGEWTEIPGAHH IIPSGFMRVVELLAEGIPAHVIQLGKPVRCIHW DQASARPRGPEIEPRGVLKRQYTSFFRPGLPTEK VAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQF VWEDEAESHTLTYPPELWYRKICGFDVLYPPER YGHVLSGWICGEEALVMEKCDDEAVAEICTEMLR QFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQ VGSSGADVEKLAKPLPYTESSKTAHGSSTKQQP GHLFSSKCPEQPLDANRGAVKPMQVLFSGEATHR KYYSTTHGALLSGQREAARLIEMYRDLFQQGT* GLSSLLRRATNS*PPACPLLPCAPAFLILCRKD FYLL*S*PP*LPSDLAL*LFFFSRLGREQVGR*V TSVLDPVPPLAYPLSCLVIVSAFNTLHFGIIKK APSPA

Frame 1

GREAERGPTQAAAAGSGPYGPGGGWRRKPGGWR RRRDGGGRDRSAARRRLTSPAQQGKVPRR*ART VCKVVNPVVTVRMTLSVAAYGEGDSLVWW*SAPA WLAWLQPKHFLSRVSRMSLCLRLPATSEAVCRV *NLDTPPLSWEPPGSMAPMGTLSII*QKPTASW KRQPMGNAAWAASASIPRMAWPATLPTTAAGSPR TWLRNSAIYTTRSIT*PRSSSGTINQSMLKVKI AWGCSPERRCVTASGMTLTTQRLPSA*SSP*SS ST*RWRAVRAAHTAWTRCP*APSGSGPRSPALTT SSPRASCGLWSCWRRASLPTSSS*GNLSAAFTG TRPQPAPEALRLSPGVC*RGSTPVSSGQACPQR RWLPSTAWALAPPTRSFWNSRSPSGALSATAYSL CGRTKQRATPSPTHLSSGTARSAALMSSTRLSA TAMC*AAGSAGRRPSSWRSVMTRQWPRSARRCC VSSQGTPTFQNLGESCARPGAATLTSAAPIHTRR WAPAGRMWRSWPSPCRTQRAQRQRMEAPQSSSL VTFSLPSAQNSPWMLTGAP*SPCRCCFPVRPPT ASTIPPPTVLCCPASVRLPASLRCTETSSSRGPE GCPRC*EEPLTRDLQPAPCCRVLLPS*SSVERI FIFCRASRPDCLQTWPCSFSFSPGWAVSRWAVE LPLCWIPCPHLPTLCPALLL*VPSILCILG**KR LPPL

Frame 2

DARRSGAPHRPRRLARAPTVPAAAGGGSQAAGG GGETEEAETGAPLAADLLPRLSRERFLEGERGR YAKL*IQW*QCG*PSQSRPTEKGTASCGGDRRR LGWPGCSQSTS*AGFHGCHCA*GFQPHRRPCAEC ETWTRHL*AGSHLDPWLPWEPYLSSSRSQRPPG RDNRWGTQRGPHQPLFQEWRGLLPYQPRPQDPQ GRG*GIQRFIQRGL*LDPGVLPAR*TSQC*KSK* RGGVHPRGGA*PHQE*P*RPRGYQAPEARHDPA VPEGGEL*EQLTQHGRGVPERLRGVDRDPRRSP HHPLGLHAGCGAAGGGHPCPRHPARETCPLHSLG PGLSPPQRP*D*APGCAKEAVHQFLPARPAHRE GGCHPPPGHWHHRQDLSGIRGALLGP*VQQPTV CVGGRSREPHPHLPT*ALVPQDLRL*CPLPA*AL RPCAERLDLRGGGPRHGEV**RGSGRDLHGDAA SVHREPQHSKTSANLALGLGQQPLLPRLLFIHA GGLQRGGCGEAGQAPAVHRELKDSAWKLHKAAAW SPFLFQVPRTAPGC*QGRRKAHAGAVFR*GHPP QVLFHHPRCSAVRPA*GCPPH*DVPRPLPAGDL RAVLAAEKSH*LVTSSLPLAAVCSCLPDPL*KGF LSSVELAALTAFRPGPVAFLFLQAGP*AGGPLS YLCAGSRAPTCLPSVLPCYCKCLQYFAFWDNKK GSLPC