Frame 0
DRYPPSGRATREADPVGLRRLPPPGLLSLPRWR
CRESTERPLRSSRRRRRRSSGAAGGDRALASPAA
ARAGQWRWRWRRRWRRRQRPRLRPPGGPRRRRA
GRTRPRVGRARTRSAAARRPGSTCWTLAPCATR
TSRAGRPSCCPACTLSASAACPRPSATSCCPRPC
WARPRPRHPSLPPARRSAARRRSPPKLESFVAQ
FAAKNVQRDTS*ITFL*RTLLRFPAVQ*KSQIR
YVQAVRTTQKPMGFV*SVLNGSARRVSELIRG*S
SQKTTLSDRKRKYLQRQLVSPASDQCFVLFIKR
SS*SCTVRHVTN*HVETVSC*NIKSIDTNL*KK
LFRIRK*S*IH*SPN*WKKQNT*NSQEIRSKTEL
LK*IKIKSRWNRILKLLYLH*W*K*IKKEKLYC
IS*RALQRTIA*NLCNNNRKWLDSLNNWSMSCI
FLNGQFPVAAVQHYFIAND*LHTGYGTSFVQGVM
HPQ*PTTPSNFTVILVSGLKISST*VL**SRIK
RASHKCLSRILSWNRIHSHQVVYHQTSYPSSQH
RSA*LNYGSSICSNSNRLHV**TFRITAPNPMDQ
FFLLILNN*DIHQTRTYHDKQ*SQTPYRWLSWL
NKP*NSGRSAVDREPHQLPTAHPLLLPAPRLLV
QQDMMERLLVHL*SI*AHQWEGLIIFPLFRILTV
QVLLCWTIL*GKILI*IMASQDHPQTERSSHQI
HQCHLQALQDLLL*LVYTPQYVHLVPPALEAEE
ALALPANQQELTLHTKSQWSCWSQFE*NKKTVDH
RKIMISLLL**SKNQMKNLGLKMPIIQEAYSPP
CS*IAVRALLLRRLC*DQMPLIVQEINLDFTRT
IPQMESLNGWILPRSHLFMLERQGKRMTPMRTGV
QFVKTEGNSSAVKSAPKYSIFLVMCPH*QIFQV
ESGFALSAETYLNQKLNMIVMLPVTTQKKRKLK
ALLS*HL*IKGSVSAYFYFFTAMK*AWLFKTLFL
*LCLIITK*LKIQWICQPSRKDYKKIIPCTQNL
KIL*LILD*SFKTVLNSMSLIQK*PMLV*NLKI
ILKNF*RTSIQKKGFPNQNSGMNQKIINLVMIQM
MTLYSPGRNASKALKNASCLNNMQHH*LVLVFR
FFCFQKNICQ*FNITTKRRVCDYSHLCFGRLLD
FDFLNSPFLLTSYH*ERKERRR*IEERKWKEGKK
EDRKRMEERSIENKDILPTSWIFKPQSGVIATV
ERK*TLYELFKLKSKKYMWFGCVL*FSFRN*YH
YP*IIWPDNMN*VYCTEEQYSTNMGGNKSSIPGG
QTVQQKGRLDAIKKALNSTSCKMATVLKKNPEN
K
Frame 1
TDTLLPAAPLGRRIPWA*GGFPRPVCFPSLAGA
AASPPSGL*GAAAGGGGGRRGRRAETALSLPRR
RQGQDNGGGGGEGGGGGGSGLGCGLRGALGGAER
GERGRESAGPGLGARRRGGPAQPVGHLRRVPPE
HPEPGAQAAALPALFLPALPARAPALPHAARAH
AGLGRDPATRPCPRLAGQRLVAVRHPSWSHSLPS
LQPRMCRETHHR*LFCEGHY*GSQQYSRKVKSG
MYKL*GQRRSQWVLCRVC*MALQDVYQSSSEGK
VHKRPHCQTERGSISRGSWCHQPATSVLSFS*KG
AAEAVL*DM*QTDMSRLSVVRT*RA*IPIYRRS
FSESESDHRYTNHQTDGKNKIHKIHRKSDPKQN
Y*SKSKSKAGGTGY*SCYIYTDGRNK*KRKSSTA
SVREPCKGPSHETYATTTGSGWTL*TIGACHAF
F*MGSFQWQQYSITL*QTTDYIPVTAPPSCKV*
CIPSDQQHHPISL*S*FLGSKYHQLRFFSNRG*R
EPATNA*AESCRGTEFTATKWFIIKPVIQVPNT
DQPSSITAPAYAATATASTFDKLSESQPQTQWT
SSSSSSSTTEISTKPEHTTTSNKAKPPTDGFLGS
TSHKTVADQQWTGNPINYQQHILYSFQPHDY*C
SRI*WKGFWFTYDRFELTSGRVL*SSLSSGY*L
FKYYYAGQYCEERY*YRSWPAKTTLKQNGPVTKF
ISAISRPCRTCYYD*CTPPNTFT*CLQRWKPRK
LWLFQQTSRS*LYTQSPSGHAGANSNKTRKQWT
TGKL*FPCCYSEARIR*RI*ASKCQLSKKHTHLP
ALK*QSELYF*GDCAKIRCP**YRRSTWTSPGQ
FLKWKV*MVGSFPEVTSSCWRDKERG*PQ*GLV
CSLSKRRGTPLL*KVPQSIPSFLSCAHIDKFSKW
RVDLHFLPRLI*TRS*I*L*CSQSQLRKKEN*R
PC*VNTYR*KEV*APTFISLLP*NEPGFSRPCS
SNCA*LLQNN*KSNGFVNHQEKTTRRLFHVLKT*
RFCS*F*IDLSKLC*IQ*A*FRSSQCWYKT*KL
F*RTSKEPLSRKKVSQTRIQE*IRR**I***FR
**LCTAPEETPQKH*RTPVA*IICSTTSLCWFLD
FFVFKKTFVSNLTSLQKEEFVTILISVLDVY*T
LISLIAHFC*PLITKKERKEGDE*KKENGKKEK
RRIEKGWKKEALKTKTFFPLLGFLNHSLE**LL*
KGNRLCMNSLS*KVKNICGLDVCFNSALEINTT
TRELYGLTI*IRCTVLKNSTPQTWVVTRVPSQE
AKRCNRRVG*MLLRRHLIVHHVRWQLY*RKIRKT
Frame 2
QIPSFRPRHSGGGSRGPEEASPARFAFPPSLAL
PRVHRAASEEQPQEEEEVVGGGGRRPRSRFPGG
GKGRTMEVAVEKAVAAAAAASAAASGGPSAAPS
GENEAESRQGPDSERGGEAARLNLLDTCAVCHQN
IQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPM
LGSAETPPPVPAPGSPVSGSSPFATQVGVIRCP
VCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQV
CTSCEDNAEANGFCVECVEWLCKTCIRAHQRVK
FTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKK
EQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEA
FQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRI
IEVNQNQKQVEQDIKVAIFTLMVEINKKGKALL
HQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHF
SKWAVSSGSSTALLYSKRLITYRLRHLLRARCD
ASPVTNNTIQFHCDPSFWAQNIINLGSLVIEDK
ESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQ
ISLAQLRLQHMQQQQPPPRLINFQNHSPKPNGP
VLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLA
QQAIKQWQISSGQGTPSTTNSTSSTPSSPTITSA
AGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDC
SSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPN
SSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGS
SGSSSKPAGADSTHKVPVVMLEPIRIKQENSGP
PENYDFPVVIVKQESDEESRPQNANYPRSILTS
LLLNSSQSSTSEETVLRSDAPDSTGDQPGLHQDN
SSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWC
AVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPS
GEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEG
LVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVP
LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKP
EDFVADFRLIFQNCAEFNEPDSEVANAGIKLENY
FEELLKNLYPEKRFPKPEFRNESEDNKFSDDSD
DDFVQPRKKRLKSIEERQLLK*YAAPLACAGF*
IFLFSKKHLSVI*HHYKKKSL*LFSSLFWTFTRL
*FP**PISVNLLSLRKKGKKEMNRRKKMERRKK
GG*KKDGRKKH*KQRHSSHFLDF*TTVWSDSYC
RKEIDFV*TL*VEK*KIYVVWMCALIQL*KLIPL
PVNYMA*QYELGVLY*RTVLHKHGW*QEFHPRR
PNGATEG*VRCY*EGT**YIM*DGNCIKEKSGK
Q
Frame 0
DRYPPSGRATREADPVGLRRLPPPGLLSLPRWR
CRESTERPLRSSRRRRRRSSGAAGGDRALASPAA
ARAGQWRWRWRRRWRRRQRPRLRPPGGPRRRRA
GRTRPRVGRARTRSAAARRPGSTCWTLAPCATR
TSRAGRPSCCPACTLSASAACPRPSATSCCPRPC
WARPRPRHPSLPPARRSAARRRSPPKLESFVAQ
FAAKNVQRDTS*ITFL*RTLLRFPAVQ*KSQIR
YVQAVRTTQKPMGFV*SVLNGSARRVSELIRG*S
SQKTTLSDRKRKYLQRQLVSPASDQCFVLFIKR
SS*SCTVRHVTN*HVETVSC*NIKSIDTNL*KK
LFRIRK*S*IH*SPN*WKKQNT*NSQEIRSKTEL
LK*IKIKSRWNRILKLLYLH*W*K*IKKEKLYC
IS*RALQRTIA*NLCNNNRKWLDSLNNWSMSCI
FLNGQFPVAAVQHYFIAND*LHTGYGTSFVQGVM
HPQ*PTTPSNFTVILVSGLKISST*VL**SRIK
RASHKCLSRILSWNRIHSHQVVYHQTSYPSSQH
RSA*LNYGSSICSNR*WLRGNRCNGGQHLWVYQT
LECRGPSSNLPSLISNRLHV**TFRITAPNPMD
QFFLLILNN*DIHQTRTYHDKQ*SQTPYRWLSW
LNKP*NSGRSAVDREPHQLPTAHPLLLPAPRLLV
QQDMMERLLVHL*SI*AHQWEGLIIFPLFRILT
VQVLLCWTIL*GKILI*IMASQDHPQTERSSHQ
IHQCHLQALQDLLL*LVYTPQYVHLVPPALEAEE
ALALPANQQELTLHTKSQWSCWSQFE*NKKTVD
HRKIMISLLL**SKNQMKNLGLKMPIIQEAYSP
PCS*IAVRALLLRRLC*DQMPLIVQEINLDFTRT
IPQMESLNGWILPRSHLFMLERQGKRMTPMRTG
VQFVKTEGNSSAVKSAPKYSIFLVMCPH*QIFQ
VESGFALSAETYLNQKLNMIVMLPVTTQKKRKLK
ALLS*HL*IKGSVSAYFYFFTAMK*AWLFKTLF
L*LCLIITK*LKIQWICQPSRKDYKKIIPCTQN
LKIL*LILD*SFKTVLNSMSLIQK*PMLV*NLKI
ILKNF*RTSIQKKGFPNQNSGMNQKIINLVMIQ
MMTLYSPGRNASKALKNASCLNNMQHH*LVLVF
RFFCFQKNICQ*FNITTKRRVCDYSHLCFGRLLD
FDFLNSPFLLTSYH*ERKERRR*IEERKWKEGK
KEDRKRMEERSIENKDILPTSWIFKPQSGVIAT
VERK*TLYELFKLKSKKYMWFGCVL*FSFRN*YH
YP*IIWPDNMN*VYCTEEQYSTNMGGNKSSIPG
GQTVQQKGRLDAIKKALNSTSCKMATVLKKNPE
NK
Frame 1
TDTLLPAAPLGRRIPWA*GGFPRPVCFPSLAGA
AASPPSGL*GAAAGGGGGRRGRRAETALSLPRR
RQGQDNGGGGGEGGGGGGSGLGCGLRGALGGAER
GERGRESAGPGLGARRRGGPAQPVGHLRRVPPE
HPEPGAQAAALPALFLPALPARAPALPHAARAH
AGLGRDPATRPCPRLAGQRLVAVRHPSWSHSLPS
LQPRMCRETHHR*LFCEGHY*GSQQYSRKVKSG
MYKL*GQRRSQWVLCRVC*MALQDVYQSSSEGK
VHKRPHCQTERGSISRGSWCHQPATSVLSFS*KG
AAEAVL*DM*QTDMSRLSVVRT*RA*IPIYRRS
FSESESDHRYTNHQTDGKNKIHKIHRKSDPKQN
Y*SKSKSKAGGTGY*SCYIYTDGRNK*KRKSSTA
SVREPCKGPSHETYATTTGSGWTL*TIGACHAF
F*MGSFQWQQYSITL*QTTDYIPVTAPPSCKV*
CIPSDQQHHPISL*S*FLGSKYHQLRFFSNRG*R
EPATNA*AESCRGTEFTATKWFIIKPVIQVPNT
DQPSSITAPAYAATGNGSEATGATEASTCGFTK
P*NAGAHPATFHLSSATASTFDKLSESQPQTQWT
SSSSSSSTTEISTKPEHTTTSNKAKPPTDGFLG
STSHKTVADQQWTGNPINYQQHILYSFQPHDY*
CSRI*WKGFWFTYDRFELTSGRVL*SSLSSGY*L
FKYYYAGQYCEERY*YRSWPAKTTLKQNGPVTK
FISAISRPCRTCYYD*CTPPNTFT*CLQRWKPR
KLWLFQQTSRS*LYTQSPSGHAGANSNKTRKQWT
TGKL*FPCCYSEARIR*RI*ASKCQLSKKHTHL
PALK*QSELYF*GDCAKIRCP**YRRSTWTSPG
QFLKWKV*MVGSFPEVTSSCWRDKERG*PQ*GLV
CSLSKRRGTPLL*KVPQSIPSFLSCAHIDKFSK
WRVDLHFLPRLI*TRS*I*L*CSQSQLRKKEN*
RPC*VNTYR*KEV*APTFISLLP*NEPGFSRPCS
SNCA*LLQNN*KSNGFVNHQEKTTRRLFHVLKT
*RFCS*F*IDLSKLC*IQ*A*FRSSQCWYKT*K
LF*RTSKEPLSRKKVSQTRIQE*IRR**I***FR
**LCTAPEETPQKH*RTPVA*IICSTTSLCWFL
DFFVFKKTFVSNLTSLQKEEFVTILISVLDVY*
TLISLIAHFC*PLITKKERKEGDE*KKENGKKEK
RRIEKGWKKEALKTKTFFPLLGFLNHSLE**LL
*KGNRLCMNSLS*KVKNICGLDVCFNSALEINT
TTRELYGLTI*IRCTVLKNSTPQTWVVTRVPSQE
AKRCNRRVG*MLLRRHLIVHHVRWQLY*RKIRK
T
Frame 2
QIPSFRPRHSGGGSRGPEEASPARFAFPPSLAL
PRVHRAASEEQPQEEEEVVGGGGRRPRSRFPGG
GKGRTMEVAVEKAVAAAAAASAAASGGPSAAPS
GENEAESRQGPDSERGGEAARLNLLDTCAVCHQN
IQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPM
LGSAETPPPVPAPGSPVSGSSPFATQVGVIRCP
VCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQV
CTSCEDNAEANGFCVECVEWLCKTCIRAHQRVK
FTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKK
EQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEA
FQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRI
IEVNQNQKQVEQDIKVAIFTLMVEINKKGKALL
HQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHF
SKWAVSSGSSTALLYSKRLITYRLRHLLRARCD
ASPVTNNTIQFHCDPSFWAQNIINLGSLVIEDK
ESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQ
ISLAQLRLQHMQQQVMAQRQQVQRRPAPVGLPN
PRMQGPIQQPSISHQQPPPRLINFQNHSPKPNG
PVLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLA
QQAIKQWQISSGQGTPSTTNSTSSTPSSPTITS
AAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDID
CSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPN
SSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRG
SSGSSSKPAGADSTHKVPVVMLEPIRIKQENSG
PPENYDFPVVIVKQESDEESRPQNANYPRSILTS
LLLNSSQSSTSEETVLRSDAPDSTGDQPGLHQD
NSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDW
CAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPS
GEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTE
GLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPV
PLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKP
EDFVADFRLIFQNCAEFNEPDSEVANAGIKLEN
YFEELLKNLYPEKRFPKPEFRNESEDNKFSDDS
DDDFVQPRKKRLKSIEERQLLK*YAAPLACAGF*
IFLFSKKHLSVI*HHYKKKSL*LFSSLFWTFTR
L*FP**PISVNLLSLRKKGKKEMNRRKKMERRK
KGG*KKDGRKKH*KQRHSSHFLDF*TTVWSDSYC
RKEIDFV*TL*VEK*KIYVVWMCALIQL*KLIP
LPVNYMA*QYELGVLY*RTVLHKHGW*QEFHPR
RPNGATEG*VRCY*EGT**YIM*DGNCIKEKSGK
Q