Sequences - Rnomics 📊 Palace

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        Rnomics 📊 Palace
    
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Sequences

Sequence NM_018156

AGGAGCGGCGGGGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAA TGATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATATGTCAATAA CCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTTGAAAGAATTGGAATTACCA TTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCCTTGGGTGATCTCCATCTCCAGCCTTCACT TAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAGGGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAA ATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTACCGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAA GATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTCCCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATG AGCCTGTACAGAAACTAATGCGGAAAAAGCAATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGAT GGAGTTACAGGAGGCCATGGCCAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCC AAGAAGCCCCTGCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCA TGGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGAATGGTGGTA TTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCGTGATGCTGTATCTTACACT GACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGAAGAGGAACAGAGCTTTGAGGAATTGAAGA TTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCGGGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGC CCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTTTCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTG GTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCCTGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGA ACACGTATACAAAGCGAGATCATGTCTTTGCCAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAAT GAATGAAAGTGCTTTCATGCAGCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGT GGACTGTTTCTTCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTG GTCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCCGGCGCACAG CCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGACTTTTTCTACAAGGGAAAG GTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATATAACAAGCTGAAGATGCAGACCAAGGCAG AAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATGGACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATT TCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGGAAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGG GATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGAATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCA ACGGAGAGAAAACACCTCCCTTTTCTGGAGTTGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTC ATTTATGGACCTCCAGATCATGGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAAC GTTCACCTACAGTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTA ATGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGATTTTTCCCCA GGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGAGGTTCTGGTGGAGTCGCAG CTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGTGCTCAAGGTGTTTGGTACCAATGCTCACT TTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGATACCATGCAGACATATGGTGCTGATTTTGACCTTTTGAT GGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGATAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACT GATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTCACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTG TGAGTTCAGAGTGCCCATCGATGAATTTAGACAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGT GGAGCTAATTGGTTTTCTTCAAAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAA GGAACTTACCAGTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAG AGAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCTTGGCTGTTT ACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATATCATCAGTGATATTGGCTAC TTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAGATCTAAACAGGAGTGTTTTCTCAACCTGA AGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCATGGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAG CGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAGCGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTT ATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTCGTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTT CTATCCCTCGGAAGCCGGGGAGTCCTGAGTTGTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGA CCGTCTGCAGGTGGAAATCAAGGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTT TGCCCACCTTCCGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACA TCCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCTGGGAACTTC TAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACAAACCCTGGACAATCTCGTG TACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCCCCTCAGTACCTGTGGAGAATCTTCTGTTG AAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATTGTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGC CACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTTGGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAA TTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGCCCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGA ACCTGATGGTGTCTCGAGGAGCCCCTAAGCCATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGA TATGCCTCGGTCTCTCCCTTCCCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTC CAAGACAAGGACTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACA TCAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTTGGATGTGCT GATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCCTCCTGAGGGCATTCTGCAC AACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCTCAAGGTTCATTCACTTTCTCTAGTGCTGA ATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAATGATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAG TCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTTCACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGA CGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGTGAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGG TGGCCTTCATTCAGCATTTCACTCAGCTGCAGGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGTGAGAGATCAAGCCCAGCGCTGTTC ACGGGTTCTCCTGGATATTGAGGCTGGTGCTCCCGTTCTCTTGATCCCAGAAAGTTCCAGATCAAATAATCTGATTGTAGCAAATTTGGGGAAGTTGAAA GTCAAAAATAAGTTTCTGTTTGCTGGTTTTCCTGGCACCTTTTCCCTACAAGATAAGGAATCTGTGCCTTCAGCTTCCCCAACGGGTATTCCCAAACACA GTCTGAGGAAAACGACAAGCACGGAGGAGCCCAGGGGAACCCATTCCCAGGGGCAGTTCACGATGCCTCTTGCTGGAATGAGCCTAGGAAGCCTGAAGAG TGAGTTTGTGCCCAGTACCTCCACCAAGCAGCAAGGGCCGCAACCCACACTGTCTGTTGGCCAAGAGTCCAGTAGTCCAGAAGACCATGTCTGCCTGCTG GATTGCGTTGTCGTGGATCTCCAGGACATGGACATCTTTGCTGCAGAGAGACATCCGAGAGAATACTCGAAGGCACCAGAGGATAGTAGTGGAGATCTGA TCTTCCCTTCCTATTTTGTGCGACAGACAGGAGGAAGCCTCTTAACCGAGCCTTGTAGGCTGAAATTGCAGGTGGAAAGGAATTTGGACAAAGAAATAAG TCATACTGTGCCAGACATATCTATCCATGGCAATCTCTCCTCAGTCCACTGCTCTCTGGATCTGTATAAATACAAGCTGATCCGCGGCTTATTAGAGAAC AACCTGGGAGAACCCATAGAGGAATTTATGCGGCCTTATGATTTACAAGATCCAAGAATTCATACTGTCCTGAGTGGAGAAGTGTACACCTGTATGTGCT TCCTCATTGATATGGTGAATGTAAGTCTGGAGCTTAAAGATCCAAAAAGAAAAGAAGGTGCTGGGTCCCTAGCCAGATTTGACTTCAAGAAATGCAAACT GCTCTATGAAAGTTTTTCCAACCAAACCAAGTCCATTAACTTGGTTTCCCATTCCATGATGGCTTTTGACACCCGTTATGCTGGGCAGAAGACCAGCCCT GGCATGACGAATGTGTTCAGCTGTATCTTTCAGCCCGCTAAGAACAGCAGCACCACCCAAGGGTCCATTCAGATTGAACTACATTTCAGATCTACCAAGG ATTCCTCCTGCTTTACAGTAGTTCTCAACAATCTCCGTGTGTTTCTCATATTTGACTGGCTACTGTTAGTCCATGATTTTCTCCACACTCCCAGTGATAT TAAGAAACAAAATCATGTTACTCCTTCTCGCCACCGTAACTCTAGCAGCGAATCTGCTATAGTTCCCAAAACTGTGAAGAGTGGAGTAGTTACCAAGCGG TCTTCCCTTCCTGTGTCCAATGAAAGGCACCTGGAGGTCAAGGTCAATGTAACAGGTACGGAGTTTGTGGTCATTGAAGATGTGTCCTGCTTCGACACCA ATGCCATTATTCTGAAAGGCACCACAGTGCTCACCTATAAGCCCCGGTTTGTTGATCGCCCCTTTTCAGGAAGTTTGTTTGGCATTGAGGTGTTTTCATG CCGACTAGGGAATGAGCATGATACAGCTCTTTCAATTGTGGATCCCGTACAAATTCAAATGGAGTTGGTGGGGAATTCTTCTTATCAAAATAGTTCAGGA TTGATGGATGCATTCAATAGTGAAGATTTCCCACCTGTCCTGGAGATTCAGTTACAAGCCCTGGATATCAGACTCTCCTATAATGATGTTCAGCTGTTTC TTGCCATTGCAAAATCCATCCCAGAGCAAGCTAATGCTGCAGTGCCAGACTCAGTGGCCCTGGAGTCAGACTCCGTTGGCACTTACCTTCCAGGTGCATC TCGCGTTGGAGAGGAAATCAGAGAAGGGACAAGACACACCTTAGATCCTGTCTTGGAGTTACAGCTGGCTAGGCTGCAGGAGCTGGGATTCAGCATGGAT GATTGTCGCAAAGCTCTTTTGGCGTGTCAAGGCCAATTGAAAAAGGCAGCAAGTTGGTTGTTTAAGAATGCGGAACCTCTGAAGTCTCTTTCCTTGGCCT CCACCAGCCGAGATAGCCCAGGGGCTGTGGCAGCGCCATTGATCTCTGGCGTGGAGATCAAAGCTGAGAGTGTGTGCATCTGTTTCATCGATGACTGCAT GGATTGTGATGTTCCTCTCGCTGAACTCACCTTTTCCCGTCTGAATTTTCTTCAGCGTGTAAGAACTAGCCCTGAAGGCTATGCCCACTTCACCCTTTCT GGAGATTATTATAACCGTGCTCTTTCAGGCTGGGAGCCATTTATTGAGCCTTGGCCATGCTCTGTATCCTGGCAACAGCAGGCAGCTAGTCGTCTCCATC CTCCTCGACTGAAGCTAGAAGCCAAGGCCAAACCTCGTTTGGATATCAATATCACTTCTGTGCTAATTGACCAGTATGTAAGTACCAAGGAATCGTGGAT GGCAGATTACTGTAAAGATGACAAGGACATAGAGTCAGCTAAATCAGAAGACTGGATGGGCTCTTCGGTGGATCCTCCATGTTTTGGACAAACAGAGGTG AAAACCCCCAAGCGCCGGCAGCCATTTGTCCCCTTTGCTCTGAGGAACCACACGGGGTGCACTTTGTGGTTTGCCACCCTGACCACCACACCCACCAGAG CTGCACTCTCTCACAGTGGGAGTCCAGGGGTAGTTCCAGAAGGGAACGGAACATTTCTCGATGATACTCACAATGTTAGTGAATGGCGAGAAGTCCTTAC AGGTGAAGAGATTCCCTTTGAATTTGAAGCAAGAGGAAAGTTAAGACACAGACACACCCATGACCTCCGGATTCATCAACTGCAAGTGAGAGTAAATGGC TGGGAGCAAGTGAGCCCAGTGTCTGTGGACAAAGTCGGGACCTTTTTTCGATATGCAGCACCAGATAAAAATTCATCTTCCTCTACGATTGGCAGCCCAA GCAGCAGAACAAATATTATACATCCCCAGGTTTATTTCTCTTCACTCCCACCAGTGCGGGTGGTCTTTGCAGTGACTATGGAAGGCAGTGCACGGAAAGT CATCACTGTCCGGTCAGCCCTCATTGTGAGGAACAGACTTGAGACACCAATGGAACTAAGACTGGATAGCCCATCAGCTCCAGACAAGCCAGTGGTGCTT CCTGCTATCATGCCAGGGGATTCGTTTGCTGTGCCTTTACACCTCACTTCTTGGCGGCTACAGGCCCGGCCCAAAGGATTGGGTGTATTTTTCTGTAAGG CTCCCATTCATTGGACCAATGTAGTGAAGACTGCAGAAATTAGTAGCAGTAAACGAGAGTGCCACTCTATGGACACAGAAAAAAGCCGATTTTTCAGGTT TTGTGTGGCTATAAAGAAAGAGAATTATCCAGATTATATGCCCTCAAACATATTTTCTGACAGTGCAAAACAGATTTTCAGACAGCCTGGGCATACCATA TATCTCCTGCCAACTGTGGTAATCTGCAACTTGCTACCCTGTGAACTTGATTTTTATGTTAAAGGAATGCCAATTAATGGGACGCTGAAACCTGGCAAGG AGGCAGCTCTCCATACAGCTGATACATCCCAGAACATTGAGCTGGGGGTATCACTGGAGAATTTCCCCCTCTGTAAAGAATTGCTCATTCCACCTGGAAC CCAAAACTATATGGTGAGAATGCGACTCTATGACGTCAACCGTCGGCAGCTGAACCTCACCATCCGGATTGTGTGTCGAGCAGAAGGATCCTTAAAGATC TTCATTTCTGCTCCATATTGGCTGATTAACAAAACAGGGTTGCCACTGATCTTCAGACAGGACAATGCCAAGACAGATGCTGCAGGCCAGTTTGAGGAGC ATGAGCTGGCCCGTAGCCTGAGTCCTCTCTTATTCTGCTATGCTGACAAAGAGCAGCCAAACCTCTGCACGATGAGAATCGGAAGGGGGATTCATCCAGA AGGCATGCCGGGCTGGTGTCAGGGCTTCTCCCTGGATGGTGGTAGTGGTGTCCGAGCTTTGAAAGTCATCCAGCAAGGAAACCGCCCAGGGCTGATCTAT AACATTGGTATTGATGTCAAGAAAGGCCGAGGTCGATACATTGATACCTGCATGGTCATCTTTGCCCCCCGTTACCTGTTAGATAATAAATCATCTCACA AGCTTGCATTTGCACAGAGGGAATTTGCCAGGGGACAGGGAACAGCCAATCCCGAAGGTTACATTTCCACCCTTCCTGGTTCCAGTGTGGTGTTCCACTG GCCTCGGAATGACTATGATCAGCTATTGTGTGTCAGACTGATGGACGTTCCCAATTGTATTTGGTCTGGAGGCTTTGAAGTCAACAAGAATAATTCCTTC CATATCAACATGAGGGATACCTTGGGAAAATGCTTCTTCCTACGAGTGGAAATTACTCTCCGAGGAGCTACGTATAGGATCTCATTTAGTGACACAGATC AGTTACCTCCTCCTTTCCGAATTGACAACTTTTCTAAGGTCCCGGTTGTCTTTACTCAGCATGGCGTAGCTGAACCCAGGCTCCGGACTGAAGTGAAGCC CATGACTTCATTGGATTATGCCTGGGACGAACCCACCTTGCCACCTTTTATCACTCTGACTGTTAAAGGGGCAGGGTCCTCTGAGATCAACTGCAACATG AATGATTTCCAGGATAATCGGCAGCTTTATTATGAAAATTTCATTTACATTGCTGCTACATATACATTCTCTGGCTTGCAGGAGGGAACAGGCAGGCCTG TGGCTTCCAACAAGGCCATTACCTGTGCGGAGCTCGTTTTGGATGTCTCACCCAAGACACAAAGAGTCATTTTAAAAAAGAAGGAACCAGGAAAGCGTTC TCAGCTGTGGAGGATGACAGGAACAGGAATGCTGGCCCATGAGGGCTCCTCAGTTCCTCACAATCCCAATAAGCCCTCAGCCGCCCGCTCCACCGAGGGG TCTGCCATCTTAGATATTGCTGGTCTCGCTGCAGTGACTGACAACAGATACGAGCCACTGATGCTGAGAAAGCCTGACCGCAGGCGAAGCACAACTCAGA CGTGGAGTTTCCGAGAAGGAAAACTGACCTGTGGGTTACATGGGTTGGTCGTCCAGGCCAAAGGAGGACTTTCTGGTTTGTTTGATGGAGCTGAAGTTGT TCTTGGTCCTGACACTTCCATGGAGCTTTTGGGGCCAGTTCCACCTGAACAACAATTTATTAATCAAAAAATGAGACCTGGTTCTGGAATGTTATCCATC AGAGTCATCCCAGATGGACCAACTAGAGCACTCCAGATAACAGATTTCTGCCACCGGAAAAGCAGCCGTTCATATGAAGTGGATGAACTTCCTGTCACCG AACAAGAGCTGCAGAAATTAAAGAATCCAGATACAGAGCAGGAATTGGAAGTGCTTGTGAGGTTAGAAGGTGGAATTGGGTTGTCCTTAATTAATAAAGT CCCAGAAGAACTGGTCTTTGCAAGTCTTACAGGAATCAATGTGCACTATACACAGCTGGCAACCAGTCACATGCTTGAACTCAGCATACAGGATGTACAG GTGGACAATCAGCTCATTGGTACCACGCAGCCCTTCATGCTCTATGTGACTCCCCTGAGCAATGAGAATGAGGTCATCGAGACCGGCCCAGCTGTGCAAG TCAACGCAGTGAAGTTCCCCAGTAAGAGTGCACTGACCAACATCTACAAGCATCTGATGATCACAGCTCAGAGATTCACAGTGCAAATTGAGGAGAAACT GCTCCTCAAGCTGCTAAGTTTCTTTGGCTACGATCAAGCAGAATCAGAGGTGGAAAAATATGATGAAAACCTCCATGAAAAGACAGCTGAGCAAGGTGGA ACACCAATTCGATACTACTTTGAAAATCTCAAAATCAGCATTCCTCAGATCAAGCTAAGTGTGTTCACCTCCAACAAGCTCCCATTGGATCTTAAGGCCC TAAAAAGCACCTTGGGGTTTCCTTTGATACGGTTTGAAGACGCTGTGATTAATCTAGATCCATTCACTCGGGTACATCCCTATGAGACCAAGGAGTTCAT CATCAATGATATCCTCAAACATTTCCAGGAGGAACTCCTCAGCCAGGCAGCTCGAATCCTGGGATCAGTGGATTTTCTTGGCAATCCTATGGGGCTTTTG AATGATGTTTCTGAAGGGGTTACTGGACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATCAAACTCTGCTGCCAAGT TTGCTGGAACATTATCAGATGGCTTAGGGAAGACGATGGACAATCGGCATCAGTCAGAGCGGGAGTACATCAGGTACCATGCAGCCACAAGTGGTGAACA CCTTGTAGCCGGCATCCATGGCCTGGCTCATGGTATCATTGGTGGACTGACCAGTGTTATAACTTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTC AGCGGTTTCATATCTGGCCTTGGAAAAGGGCTTGTTGGCACTGTAACCAAGCCAGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGA GAGACACAGCCACACTCAGCGGCCCCAGGACTCAAGCACAGAGGGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGA GAGCCAGGCGGAAGGACAGGAGCAGCTCTTCAAACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTC ATCTCCTCCAAAGCTGTTTACTTCCTGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTTG TCTCCAAAGACCATGGGAAGGTGTATGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCACCAGAAGCCCAT GGTCCATGTGAAATCTGAGGTCCTTGCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAGCAGCTTATGTTAAGACTCAGC GAAAACCGAGAGCAGCTGGAGCTGGACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCGCAGACCCACCAGGAGGAAAGAGGCCCAGCTC TCAGCTGACGATGGAGGCAGAACCGGAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGGGAAAGTAAATCCTCATGAGGAAAAGTACAAATGGAAATCGT ATTAATTTGTGAGGCAGGGAGTTATTTTAGATTATGGGAAATAATTTTTAAAGGTATTGGTTAAATAACGTTTAAAAACATGTACTGAGATGAATCTAAT TTTTAGATTGCCCTGTATTTTGTTAACATGTATATATGTACAACAGTGTGTTTGTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAA GGTTTGTTAACTGTAAAGTAATATAAAGTTATATTGGATCTTCTATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTA AAAGTTAAAGAATGTTACGTCTTAGTTTTGGAGACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACAT CGTGGCTGTCCAGTTGGGCTGTGAGCTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTCT CACCCCCATTTTACAAAGAGTGCTTAGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACTTAGGGGGAAAC CTGTGCTCCATTACCACATGGGTGCAAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACATTGGTAAACTCTGTTGATTGAG AAGGAAAAAAAAAGTCCCATTGAACTGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCTGGGCAGCAACAACCAAGAACAAAGCCCCGGG ACTGTTTTCTTTTTAATAAAGCCACAGGCAGGCATCGTAGCTCCACAGCCCGAGGGGACACAGGATGGAAACCCCAGGATGAGAAGGGAGCAGGGAGAGT TCCAGAAAGGGGGATGAAATAGGAGTATTAAAAAGCTGCGTTGGTAAGTTTTTCATGGAACCAAGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAA TTCCTGCTGGGAGCAAGGCCTGGTATGAGCGCCCTGGGTCTTGTTTTTGGTGTTTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGG CCTCACTTTAGAATGAATGAGTCACCTTGTGATTTTTAAATTTTTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGG ATGACTCAGTGGATCAGTGGATGCGTGGAAGGTTTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCC CTTTCCTCTCCCACTTCCCCTCTGTGTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAGC TTTAGCACAAGTAGCTACATAGTGTTCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGATTGCAGAATGGA AACTTGGCTTTTGCGGCACTGGGTGAGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTCACGCACTGCACAAGATGGCAG CAGGATACAGCACTGCACAAGATGGCAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCCCACAGGTTTGGCTTGTGGTTTTTGTCATCAG TAACCTACTGCCTGAGATCATGATCTCTTAAAAGATGAGACTCTCGGAAGGGTTGATTGTATGCGTCAGTGAGCCTTCTATCACCTTCTGGAACAAAGTC ACTTGAAATCTCTTGATGAGATTAAGGAGTTTAGTGTTACTAAGAAAATCTGCTTTGGGCCGCAGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGT TAGCTGCGGGCTGCCCTGTGGGCTGGTGCTTCAGGAGGAATCCAGAGAAGTGTTCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAA ATAGCTGCCCATCTCCTGTGATTGCACAACCAAGCACTTTGACATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGG GGCTGGGTGGGAGATGGGAGGGCCAACTGCGAGCTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGG GCATTTGACATCCCCTCCTGGTTCTCACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTAA ACTGATATTCAGCCAGCAATGCCTAAGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAGGAAAGTAAAAT AAATGGAATAAGAGTAAATTGGGTAAGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGTGTCACTCCCTGGCTGTCGCTG CTTCTCTGTGCTCACTGAAGGGTGAGCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACAGTGGAAAACAGACAAGCGGCCCCTTCCCCAA ATCCCAAGAGTGTCTTGCTGCTTGGTGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGGGCCACTTTGTTTGTAAGTATGATCTGGGCCTCAAAATACCA TAGTAGCTGCTTGATAAAATTCTAAAAATATCTGGTTCTCTATTATGTAAACACTATTACAGTCACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATA TCAGAGTCATCATTTTTCTTCCTGTGGAATAAAATGCCTTGTGGACTTCCCAAA

refseq_VPS13D.F1 (forward primer)
refseq_VPS13D.R1 (reverse primer)
Single exon skipping

Frame 0

RSGGEETPRSAGLGRAARDTDRFFCDHEREK*R MIHDF*TPFPEDIVMLEGLVAWVLNTYLGKYVNN LNTDQLSVALLKGAVELENLPLKKDALKELELP FEVKAGFIGKVTLQIPFYRPHVDPWVISISSLH LIGAPEKIQDFNDEKEKLLERERKKALLQALEEK WKNDRQQKGESYWYSVTASVVTRIVENIELKIQ DVHLRFEDGVTNPSHPFAFGICIKNVSMQNAVN EPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQM ELQEAMARSMESRSHHYVLEPVFASALLKRNCS KKPLRSRHSPRIDCDIQLETIPLKLSQLQYRQI MEFLKELERKERQVKFRRWKPKVAISKNCREWWY FALNANLYEIREQRKRCTWDFMLHRARDAVSYT DKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELK ILRELVHDRFHKQEELAESLREPQFDSPGACPGA PEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNV VEGLSAEQQEQWIPEEILGTEEFFDPTADASCM NTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQM NESAFMQLEFSDVKLLAESLPRRNSSLLSVRLG GLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSF GLQTTSADRSDHYPAADPDGPVFEMLYERNPAHS HFERRLNVSTRPLNIIYNPQAIKKVADFFYKGK VHTSGFGYQSELELRVAEAARRQYNKLKMQTKA EIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSR DGSASEETQFSDDEYKTPLATPPNTPPPESSSS NGEKTPPFSGVEFSEEQLQAHLMSTKMYERYSLS FMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFN VHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHI NEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQ EEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQ LLLAEFKVNCMQLGVESNGRYISVLKVFGTNAH FVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLM ASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLT DGATLNDRSATSVSLDKILTKEQESLIKLEYQF VSSECPSMNLDSTLQVISLQVNNLDIILNPETIV ELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQ GTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANR EKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCL QLMDLTQDNVKNQYVVSIGNSVGYENIISDIGY FESVFVRMEDAALTEALSFTFVERSKQECFLNL KMASLHYNHSAKFLKELTLSMDELEENFRGMLKS AATKVTTVLATKTAEYSEMVSLFETPRKTREPF ILEENEIYGFDLASSHLDTVKLILNINIESPVV SIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSD RLQVEIKDIKLYSLNCTQLAGREAVGSEGSRMF CPPSGSGSANSQEEAHFTRHDFFESLHRGQAFH ILNNTTIQFKLEKIPIERESELTFSLSPDDLGTS SIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLV YSEDLNKYPASATSSPCPDSPLPPLSTCGESSV ERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVE FSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYK NLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPD MPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEV QDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVH INIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVL ITLQTWVVILDFFGIGSTADNHAMRLPPEGILH NVKLEPHASMESGLQDPVNTKLDLKVHSLSLVL NKTTSELAKANVSKLVAHLEMIEGDLALQGSIGS LSLSDLTCHGEFYRERFTTSGEEALIFQTFKYG RPDPLLRREHDIRVSLRMASVQYVHTQRFQAEV VAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCS RVLLDIEAGAPVLLIPESSRSNNLIVANLGKLK VKNKFLFAGFPGTFSLQDKESVPSASPTGIPKH SLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKS EFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLL DCVVVDLQDMDIFAAERHPREYSKAPEDSSGDL IFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEIS HTVPDISIHGNLSSVHCSLDLYKYKLIRGLLEN NLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMC FLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKL LYESFSNQTKSINLVSHSMMAFDTRYAGQKTSP GMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTK DSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDI KKQNHVTPSRHRNSSSESAIVPKTVKSGVVTKR SSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDT NAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSC RLGNEHDTALSIVDPVQIQMELVGNSSYQNSSG LMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLF LAIAKSIPEQANAAVPDSVALESDSVGTYLPGAS RVGEEIREGTRHTLDPVLELQLARLQELGFSMD DCRKALLACQGQLKKAASWLFKNAEPLKSLSLA STSRDSPGAVAAPLISGVEIKAESVCICFIDDCM DCDVPLAELTFSRLNFLQRVRTSPEGYAHFTLS GDYYNRALSGWEPFIEPWPCSVSWQQQAASRLH PPRLKLEAKAKPRLDINITSVLIDQYVSTKESWM ADYCKDDKDIESAKSEDWMGSSVDPPCFGQTEV KTPKRRQPFVPFALRNHTGCTLWFATLTTTPTR AALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNG WEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSP SSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKV ITVRSALIVRNRLETPMELRLDSPSAPDKPVVL PAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCK APIHWTNVVKTAEISSSKRECHSMDTEKSRFFRF CVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTI YLLPTVVICNLLPCELDFYVKGMPINGTLKPGK EAALHTADTSQNIELGVSLENFPLCKELLIPPGT QNYMVRMRLYDVNRRQLNLTIRIVCRAEGSLKI FISAPYWLINKTGLPLIFRQDNAKTDAAGQFEE HELARSLSPLLFCYADKEQPNLCTMRIGRGIHPE GMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIY NIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSH KLAFAQREFARGQGTANPEGYISTLPGSSVVFHW PRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSF HINMRDTLGKCFFLRVEITLRGATYRISFSDTD QLPPPFRIDNFSKVPVVFTQHGVAEPRLRTEVKP MTSLDYAWDEPTLPPFITLTVKGAGSSEINCNM NDFQDNRQLYYENFIYIAATYTFSGLQEGTGRP VASNKAITCAELVLDVSPKTQRVILKKKEPGKRS QLWRMTGTGMLAHEGSSVPHNPNKPSAARSTEG SAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQ TWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVV LGPDTSMELLGPVPPEQQFINQKMRPGSGMLSI RVIPDGPTRALQITDFCHRKSSRSYEVDELPVT EQELQKLKNPDTEQELEVLVRLEGGIGLSLINKV PEELVFASLTGINVHYTQLATSHMLELSIQDVQ VDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQ VNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKL LLKLLSFFGYDQAESEVEKYDENLHEKTAEQGG TPIRYYFENLKISIPQIKLSVFTSNKLPLDLKA LKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFI INDILKHFQEELLSQAARILGSVDFLGNPMGLL NDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK FAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEH LVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGV SGFISGLGKGLVGTVTKPVAGALDFASETAQAV RDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSE SQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVL ISSKAVYFLKSGDYVDREAIFLEVKYDDLYHCL VSKDHGKVYVQVTKKAVSTSSGVSIPGPSHQKPM VHVKSEVLAVKLSQEINYAKSLYYEQQLMLRLS ENREQLELDS*SPAAEMGAPDTAQTHQEERGPA LS*RWRQNRSRVWGSCQGMRESKSS*GKVQMEIV LICEAGSYFRLWEIIFKGIG*ITFKNMY*DESN F*IALYFVNMYICTTVCL*IYRNVSEQGLCYV* RFVNCKVI*SYIGSSIALILDV*FRILSIERHS* KLKNVTS*FWRLKYSQ*SGLR*GLWS*KGRL*H RGCPVGL*AVAPRTGAGPSEGSRRGAWEPTFNF SPPFYKECLDSYKL*CKLSIWLFPN*SYQT*GET CAPLPHGCKSAL*VFSGYYY*RGWKHW*TLLIE KEKKSPIELLQQIRNPHKSALLPGQQQPRTKPR DCFLFNKATGRHRSSTARGDTGWKPQDEKGAGRV PERGMK*EY*KAALVSFSWNQDLTKASLILGFK FLLGARPGMSALGLVFGVSLFCKD*ADREKGKG ASL*NE*VTL*FLNFYFNKANQFLQPCHM*LSLG *LSGSVDAWKVLVFITHDPNPSKTQMKLIFFPS LSSPTSPLCLCLCVCVCVCVCARARACREEGRE L*HK*LHSVQGSAFLNSEAWLPLLNSKLVDCRME TWLLRHWVSFSLCVSCWGVVMIVSALTHCTRWQ QDTALHKMAAPLQLPPQPPSLHPHRFGLWFLSS VTYCLRS*SLKR*DSRKG*LYASVSLLSPSGTKS LEIS**D*GV*CY*ENLLWAAAVLGVLRPD*GS *LRAALWAGASGGIQRSVQMPPLGSFLILISSL NSCPSPVIAQPSTLTFAP*ERQMLKWNPKTT*GG AGWEMGGPTASCSTSQLSPALQPWARQGQKVSG AFDIPSWFSPGKHPKLWRKQALPLAP*MPRLFV N*YSASNA*DFVKIISTAFLSASNTQFVSEESKI NGIRVNWVRRYPKLPSPLTQHSWPTRVTPWLSL LLCAH*RVSQASASPAPGPGHYTVENRQAAPSP NPKSVLLLGGCSSQCSEGSRATLFVSMIWASKYH SSCLIKF*KYLVLYYVNTITVTSV*RLLSLVLI SESSFFFLWNKMPCGLPK

Frame 1

GAAGRKRRAAPGWGGRPGTPTDFSVTMKERNKE *SMISKHLFLRI*SCWKAL*PGFSIPIWENMSI T*TLTSSQLHFSKVLLN*KTCH*RKMP*KNWNYH LKSKLASLGK*PFRFPFIAPMWTLG*SPSPAFT *LEPQRKYRISMMKRRSCWKGNVRKHYFKPWRR NGRMTASRKGSPIGIQLPPP*LQGLWRILN*KFK MSIYALKMVSPIPPILLLLASALRMCPCKML*M SLYRN*CGKSN*T*QNLASIGMSIALYWGICLR WSYRRPWPGAWRVAAITTSWSLCLHLLF*RETAP RSPCGLGTVPVLIVIFSWRPFP*NSLSCNTGKS WNSSRSWNERRGR*SSEGGNPRWRYLRTAENGG ILL*MLTCMRSESRGNVAPGTLCCTALVMLYLTL TNISTS*KEACCPQMTRRKCVGLKRNRALRN*R FCVNWFMIDFTNRKN*QRVCGSLSLILQEPVRE PQNPVEAVGCCSISSPGFLDGVAGTGSRPQKGMW LRDCQQSNRSSGFLKRSWALRSFLTPLQMPRV* TRIQSEIMSLPN*ICSCSEVQ*LCYTRSKELLK *MKVLSCSSSFQM*NF*QSLFLEEIPRCFQSGWV DCFFETWLQKELCFLF*SSLIHKKKLAESHNLL VYKLHLQTEVIITQLQIQMAPFLRCCMREIRRT ATLRGGSMSAQGP*TSYTIRRPLKK*QTFSTRER FIPQVLVISLNLS*EWLKLPEDNITS*RCRPRQ KSGKLLIVC*WVISLRRVNDGPCGWIFLPLR*Y FLMISNSRILC*LSWI*EECF*RTPKITPGGKVG MGQHLKRPSLVMMNIRPPWPHLLTPHLPSQAAA TERKHLPFLELSSVKNSFKHI**AQRCMRGTRC HLWTSRSWLDE*KTIGSMSRILTWDQHMW*RSST FTYS*SVD*FILQIPNIQEPCSQATYQT*KSTL MKIKYLH*RIALLSSPPQK*KLLTLRLKKRFFP RRSSGEVCKTP**I*PRALCCWSSIPARFWWSRS SSWRNLK*TVCSLVLRAMAGTFLCSRCLVPMLT L*RGLMMLKSP*LFMVCSWWIPCRHMVLILTF* WLHIRT*ALIFQREAFGIAGPSLLSLDRMWPT*L MELH*TTDQLLVFHLTKFLPKSKSPLLSWNISL *VQSAHR*I*TVLFR*FPYR*II*ILSSIQRRL WS*LVFFKNPFPRKKMI*VLNL**LILKEASENK ELTSLHMNKTLRLQWKSIG*TYCFFGQWAWQIE RNMAEKLQLQV*VAPKLMSQWVARLT*MVLLAV YSLWI*HKITLKTSMLSALGIL*AMKISSVILAT LNLCLSEWKMQPSLKL*VSRLLRDLNRSVFST* RWLLYIITTLLSF*RS*RYPWMNWKKIFEVC*K AQPPKSPQY*LPRLPSIARWYRSLKLQGRLGNPL S*RKMKYMGLT*LRLIWTL*S*S*T*TLNHQLF LSLGSRGVLSCWWDTWDRYSSRILWREMMNPEV TVCRWKSRTLNCIL*IAPSWQVEKLLGLKEAGCF AHLPGLAVPTVRRKLISHDMISLNLCIEVKLFT S*TTPPFSLNWRRSL*RENLN*LFLLAQMTWEL LAS*RLKENLSIQFRWC*QSMYMSRFYKPWTISC TVKI*ISIQPVLPPPLALILLCLPSVPVENLLL KGRRMDCSATPAFLTPLRSHCQ*RKSNPLLRFK PPFVYQSFRFS*VEI*LWGPKVL*A*SFRTLRWN SVKTIPRLYLFRLPCILC*WRTYWRRIQILNIR T*WCLEEPLSHLV*HKKNTFLSLAPQCPMWNIL ICLGLSLPTWKKLLMSSSCIKGPPLRPGKSKRKS KTRTIP*PHLLLQQWMSPRYLLERVNLMIP*ST STYSW*IRNIQNSLPVTIELTGALMLILIAWMC *SHCKPGL*Y*TFLESAPLQTTTQ*GCLLRAFCT T*SWSHMPPWSLDFRIQ*TPNWISRFIHFL*C* IRPPVSLPKQMCPN**HTWK*LRETWPYRAALG VCL*VTSHAMESSTENGSLPVVKKHSSSRLLNTD GLTLCSGENTTFA*ASGWPLCSMCILSVSRQRW WPSFSISLSCRMS*GASELLLRGRR*EIKPSAV HGFSWILRLVLPFS*SQKVPDQII*L*QIWGS*K SKISFCLLVFLAPFPYKIRNLCLQLPQRVFPNT V*GKRQARRSPGEPIPRGSSRCLLLE*A*EA*R VSLCPVPPPSSKGRNPHCLLAKSPVVQKTMSACW IALSWISRTWTSLLQRDIRENTRRHQRIVVEI* SSLPILCDRQEEAS*PSLVG*NCRWKGIWTKK* VILCQTYLSMAISPQSTALWICINTS*SAAY*RT TWENP*RNLCGLMIYKIQEFILS*VEKCTPVCA SSLIW*M*VWSLKIQKEKKVLGP*PDLTSRNAN CSMKVFPTKPSPLTWFPIP*WLLTPVMLGRRPAL A*RMCSAVSFSPLRTAAPPKGPFRLNYISDLPR IPPALQ*FSTISVCFSYLTGYC*SMIFSTLPVI LRNKIMLLLLATVTLAANLL*FPKL*RVE*LPSG LPFLCPMKGTWRSRSM*QVRSLWSLKMCPASTP MPLF*KAPQCSPISPGLLIAPFQEVCLALRCFH AD*GMSMIQLFQLWIPYKFKWSWWGILLIKIVQD *WMHSIVKISHLSWRFSYKPWISDSPIMMFSCF LPLQNPSQSKLMLQCQTQWPWSQTPLALTFQVH LALERKSEKGQDTP*ILSWSYSWLGCRSWDSAWM IVAKLFWRVKAN*KRQQVGCLRMRNL*SLFPWP PPAEIAQGLWQRH*SLAWRSKLRVCASVSSMTA WIVMFLSLNSPFPV*IFFSV*ELALKAMPTSPFL EIIITVLFQAGSHLLSLGHALYPGNSRQLVVSI LLD*S*KPRPNLVWISISLLC*LTSM*VPRNRG WQITVKMTRT*SQLNQKTGWALRWILHVLDKQR* KPPSAGSHLSPLL*GTTRGALCGLPP*PPHPPE LHSLTVGVQG*FQKGTEHFSMILTMLVNGEKSL QVKRFPLNLKQEES*DTDTPMTSGFINCK*E*MA GSK*AQCLWTKSGPFFDMQHQIKIHLPLRLAAQ AAEQILYIPRFISLHSHQCGWSLQ*LWKAVHGK SSLSGQPSL*GTDLRHQWN*DWIAHQLQTSQWCF LLSCQGIRLLCLYTSLLGGYRPGPKDWVYFSVR LPFIGPM**RLQKLVAVNESATLWTQKKADFSG FVWL*RKRIIQIICPQTYFLTVQNRFSDSLGIPY ISCQLW*SATCYPVNLIFMLKECQLMGR*NLAR RQLSIQLIHPRTLSWGYHWRISPSVKNCSFHLE PKTIW*ECDSMTSTVGS*TSPSGLCVEQKDP*RS SFLLHIG*LTKQGCH*SSDRTMPRQMLQASLRS MSWPVA*VLSYSAMLTKSSQTSAR*ESEGGFIQ KACRAGVRASPWMVVVVSEL*KSSSKETAQG*SI TLVLMSRKAEVDTLIPAWSSLPPVTC*IINHLT SLHLHRGNLPGDREQPIPKVTFPPFLVPVWCST GLGMTMISYCVSD*WTFPIVFGLEALKSTRIIPS IST*GIPWENASSYEWKLLSEELRIGSHLVTQI SYLLLSELTTFLRSRLSLLSMA*LNPGSGLK*S P*LHWIMPGTNPPCHLLSL*LLKGQGPLRSTAT* MISRIIGSFIMKISFTLLLHIHSLACRREQAGL WLPTRPLPVRSSFWMSHPRHKESF*KRRNQESV LSCGG*QEQECWPMRAPQFLTIPISPQPPAPPRG LPS*ILLVSLQ*LTTDTSH*C*ESLTAGEAQLR RGVSEKEN*PVGYMGWSSRPKEDFLVCLMELKL FLVLTLPWSFWGQFHLNNNLLIKK*DLVLECYPS ESSQMDQLEHSR*QISATGKAAVHMKWMNFLSP NKSCRN*RIQIQSRNWKCL*G*KVELGCP*LIK SQKNWSLQVLQESMCTIHSWQPVTCLNSAYRMYR WTISSLVPRSPSCSM*LP*AMRMRSSRPAQLCK STQ*SSPVRVH*PTSTSI**SQLRDSQCKLRRN CSSSC*VSLATIKQNQRWKNMMKTSMKRQLSKVE HQFDTTLKISKSAFLRSS*VCSPPTSSHWILRP *KAPWGFL*YGLKTL*LI*IHSLGYIPMRPRSS SSMISSNISRRNSSARQLESWDQWIFLAILWGF* MMFLKGLLD**NMEMSGASSEMLHTEYQTLLPS LLEHYQMA*GRRWTIGISQSGSTSGTMQPQVVN TL*PASMAWLMVSLVD*PVL*LRQWKV*KQKGVS AVSYLALEKGLLAL*PSQWQAPWILHQKQPRR* ETQPHSAAPGLKHRGFGNRVAARGPRGCFPDIL RARRKDRSSSSNSQTTYRTNSSSLWRTLTATACS SPPKLFTS*KVETTWIEKPFS*KSNTMTSTTAL SPKTMGRCMCR*PRKP*ARAVECPSPAPPTRSP WSM*NLRSLLSSCHKK*TTQRASTMNSSLC*DSA KTESSWSWTPEAPLLRWALPTQRRPTRRKEAQL SADDGGRTGVGFGEVVKE*GKVNPHEEKYKWKS Y*FVRQGVILDYGK*FLKVLVK*RLKTCTEMNLI FRLPCILLTCIYVQQCVCKYIGTFLNRVCAMCK GLLTVK*YKVILDLLLH*F*MSNSGYCL*KGIL KS*RMLRLSFGD*SIPSKVG*GEGCGPERDAFDI VAVQLGCELWHPGLALALQKDLGEGLGSPLLIS HPHFTKSA*ILTNYDVSYPFGFFLTSLTKLRGK PVLHYHMGASQHCKFSQVIIIREVGNIGKLC*LR RKKKVPLNCCNKSEIHIKVLSCLGSNNQEQSPG TVFFLIKPQAGIVAPQPEGTQDGNPRMRREQGE FQKGG*NRSIKKLRW*VFHGTKI*QRHLLSLVLN SCWEQGLV*APWVLFLVFRFSVRIKQIGRREKG PHFRMNESPCDF*IFILIKLINFYNLVTCS*VW DDSVDQWMRGRFWCL*LMTQILPRHK*S*SSSPP FPLPLPLCVCVCVCVCVCVCARARVHAERKEGS FSTSSYIVFKDQLS*TPRLGCLC*TPS*WIAEW KLGFCGTG*VLVCVCLAGGW**LSQHSRTAQDGS RIQHCTRWQLLCSFLLSLPPCTPTGLACGFCHQ *PTA*DHDLLKDETLGRVDCMRQ*AFYHLLEQS HLKSLDEIKEFSVTKKICFGPQQCWVFSDLTEEV SCGLPCGLVLQEESREVFRCPPWAPF*F*SAL* IAAHLL*LHNQAL*HLHLRRGRC*NGIQRPPRA GLGGRWEGQLRAAPLLSSPLPCSPGPDKARRFQG HLTSPPGSHQENIQSFGGNRPCPWLLKCPVSL* TDIQPAMPKTLLRSFLLLFFLLQTHSSSLRKVK *ME*E*IG*GDIQSYPVP*PSTVGRPVSLPGCRC FSVLTEG*ARPVLPQPLGLVTTQWKTDKRPLPQ IPRVSCCLVGAHRNVLKAPGPLCL*V*SGPQNT IVAA**NSKNIWFSIM*TLLQSPVCEDS*VWFSY QSHHFSSCGIKCLVDFP

Frame 2

ERRGGNAAQRRAGAGGPGHRQIFL*P*KREIKN DP*FLNTFS*GYSHVGRPCSLGSQYLFGKICQ* PEH*PALSCTSQRCC*IRKLAIKERCLERIGIT I*SQSWLHWESNPSDSLLSPPCGPLGDLHLQPSL NWSPRENTGFQ**KGEAVGKGT*ESTTSSPGGE MEE*PPAERGVLLVFSYRLRSYKDCGEY*IKNS RCPFTL*RWCHQSLPSFCFWHLH*ECVHAKCCE* ACTETNAEKAIRRSRI*HLLGCRLHFTGGFASD GVTGGHGQEHGESQPSLRPGACVCICSFEEKLL QEAPAVSAQSPY*L*YSAGDHSLETLSAAIPANH GIPQGAGTKGEAGEVPKVETQGGDI*ELPRMVV FCFEC*LV*DQRAEETLHLGLYVAPRS*CCILH *QIFQQVKRRPAVHR*QGGNVSD*RGTEL*GIED FA*TGS*SISQTGRTSRESAGASV*FSRSLSGS PRTRWRQWDAAVSPVLVSWMGWLVRAADPRREC G*GTVSRATGAVDS*RDPGH*GVF*PHCRCLVYE HVYKARSCLCQTEFAVAARYSDSVTQGARNSSN E*KCFHAARVFRCKTSSRVSSSKKFLVAFSPVG WTVSSRPGYRRNYVSSSSLP*STKRSWQSLTIFW STNYICRQK*SLPSCRSRWPRF*DAV*EKSGAQ PL*EAAQCQHKALEHHIQSAGH*KSSRLFLQGK GSYLRFWLSV*T*AESG*SCPKTI*QAEDADQGR NPANS*SFASG*FH*GE*TMDRAAGYFCPSGDI S**FQIQESCVSCRGSRKNAFDEHPR*LQEEK* GWVSI*RDPV****I*DPPGHTS*HPTSRVKQQQ RRENTSLFWS*VQ*RTASSTFNEHKDV*EVLAV IYGPPDHGWTSERQLEACPGY*RGTNTCGREVQ RSPTVRASIDLYFRSQISRSRALRQLTRLKNPH* *R*NICTKELLCSPHHPRNENF*HSD*RKDFSP GGAAGKFARLRNEFNPEHCVVGAAYPRGSGGVA APPGGI*SELYAAWC*EQWPVHFCAQGVWYQCSL CEEAL*C*SLPNCSWFAPGGYHADIWC*F*PFD GFT*ELEL*YSNGKPSG*QGPVSCLWTECGPLN *WSYTERPISY*CFT*QNSYQRARVPY*VGISVC EFRVPIDEFRQYSSGDFPTGE*FRYYPQSRDDC GANWFSSKILSQGKR*FKSSTFND*F*KKLQRT RNLPVYI*TKH*GCSGNP*AELTASSDSGHGK*R EIWQKNCNCKYRWHQS*CLNG*HV*HEWFSWLF TAYGFDTR*R*KPVCCQHWEFCRL*KYHQ*YWL L*ICVCQNGRCSPH*SFEFHVC*EI*TGVFSQPE DGFFTL*PLC*VFEGVDVIHG*TGRKFSRYAEK RSHQSHHSTSYQDCRV*RDGIAL*NSKEDSGTL YLRGK*NIWV*PSFVSFGHCKANLEHKH*ITSCF YPSEAGES*VVGGTLGTDIHPEFCGGR**IQK* PSAGGNQGH*TVFFELHPVGR*RSCWV*RKPDV LPTFRVWQCQQSGGSSFHTT*FL*IFA*RSSFSH PEQHHHSV*TGEDPYRERI*IDFFS*PR*PGNF *HHED*RKICQSSSGGVSKACI*AGFTNPGQSR VQ*RSE*VSSQCYLLPLP*FSSASPQYLWRIFC* KEGEWIVQPLQPF*HLSEVIVSEGSQILYSDSS HLLYIRASGSAKWRSDFGGPRSCELKVSGL*GG IQ*RPSPDFIYSDCPAFSADGGLIGEESRF*I*E PDGVSRSP*AI*FSTKRIPFSVLPLSVQCGIS* YASVSPFPHGRSS*CLPVVSKAHLCVPEKAKGS PRQGLSLDPTSFSNSG*AQDTCWKE*I**FLSPH QHILGR*ETSRILFQLQSS*PEH*C*F*LLGCA DHTANLGCDIRLFWNRLHCRQPRNEAAS*GHSA QREVGATCLHGVWTSGSSEHQTGSQGSFTFSSAE *DHQ*ACQSKCVQISSTPGND*GRPGLTGQHWE SVSK*PHMPWRVLQRTVHYQW*RSTHLPDF*IR TA*PSAPERTRHSREPPDGLCAVCAYSAFPGRGG GLHSAFHSAAGCLRAPASCY*GADGERSSPALF TGSPGY*GWCSRSLDPRKFQIK*SDCSKFGEVE SQK*VSVCWFSWHLFPTR*GICAFSFPNGYSQTQ SEENDKHGGAQGNPFPGAVHDASCWNEPRKPEE *VCAQYLHQAARAATHTVCWPRVQ*SRRPCLPA GLRCRGSPGHGHLCCRETSERILEGTRG**WRSD LPFLFCATDRRKPLNRAL*AEIAGGKEFGQRNK SYCARHIYPWQSLLSPLLSGSV*IQADPRLIRE QPGRTHRGIYAAL*FTRSKNSYCPEWRSVHLYVL PH*YGECKSGA*RSKKKRRCWVPSQI*LQEMQT AL*KFFQPNQVH*LGFPFHDGF*HPLCWAEDQP WHDECVQLYLSAR*EQQHHPRVHSD*TTFQIYQG FLLLYSSSQQSPCVSHI*LATVSP*FSPHSQ*Y *ETKSCYSFSPP*L*QRICYSSQNCEEWSSYQA VFPSCVQ*KAPGGQGQCNRYGVCGH*RCVLLRHQ CHYSERHHSAHL*APVC*SPLFRKFVWH*GVFM PTRE*A*YSSFNCGSRTNSNGVGGEFFLSK*FR IDGCIQ**RFPTCPGDSVTSPGYQTLL**CSAVS CHCKIHPRAS*CCSARLSGPGVRLRWHLPSRCI SRWRGNQRRDKTHLRSCLGVTAG*AAGAGIQHG *LSQSSFGVSRPIEKGSKLVV*ECGTSEVSFLGL HQPR*PRGCGSAIDLWRGDQS*ECVHLFHR*LH GL*CSSR*THLFPSEFSSACKN*P*RLCPLHPF WRLL*PCSFRLGAIY*ALAMLCILATAGS*SSPS SSTEARSQGQTSFGYQYHFCAN*PVCKYQGIVD GRLL*R*QGHRVS*IRRLDGLFGGSSMFWTNRG ENPQAPAAICPLCSEEPHGVHFVVCHPDHHTHQS CTLSQWESRGSSRRERNISR*YSQC**MARSPY R*RDSL*I*SKRKVKTQTHP*PPDSSTASESKW LGASEPSVCGQSRDLFSICSTR*KFIFLYDWQPK QQNKYYTSPGLFLFTPTSAGGLCSDYGRQCTES HHCPVSPHCEEQT*DTNGTKTG*PISSRQASGA SCYHARGFVCCAFTPHFLAATGPAQRIGCIFL*G SHSLDQCSEDCRN**Q*TRVPLYGHRKKPIFQV LCGYKERELSRLYALKHIF*QCKTDFQTAWAYH ISPANCGNLQLATL*T*FLC*RNAN*WDAETWQG GSSPYS*YIPEH*AGGITGEFPPL*RIAHSTWN PKLYGENATL*RQPSAAEPHHPDCVSSRRILKD LHFCSILAD*QNRVATDLQTGQCQDRCCRPV*GA *AGP*PESSLILLC*QRAAKPLHDENRKGDSSR RHAGLVSGLLPGWW*WCPSFESHPARKPPRADL *HWY*CQERPRSIH*YLHGHLCPPLPVR**IISQ ACICTEGICQGTGNSQSRRLHFHPSWFQCGVPL ASE*L*SAIVCQTDGRSQLYLVWRL*SQQE*FL PYQHEGYLGKMLLPTSGNYSPRSYV*DLI**HRS VTSSFPN*QLF*GPGCLYSAWRS*TQAPD*SEA HDFIGLCLGRTHLATFYHSDC*RGRVL*DQLQH E*FPG*SAALL*KFHLHCCYIYILWLAGGNRQAC GFQQGHYLCGARFGCLTQDTKSHFKKEGTRKAF SAVEDDRNRNAGP*GLLSSSQSQ*ALSRPLHRG VCHLRYCWSRCSD*QQIRATDAEKA*PQAKHNSD VEFPRRKTDLWVTWVGRPGQRRTFWFV*WS*SC SWS*HFHGAFGASST*TTIY*SKNETWFWNVIH QSHPRWTN*STPDNRFLPPEKQPFI*SG*TSCHR TRAAEIKESRYRAGIGSACEVRRWNWVVLN**S PRRTGLCKSYRNQCALYTAGNQSHA*TQHTGCT GGQSAHWYHAALHALCDSPEQ*E*GHRDRPSCAS QRSEVPQ*ECTDQHLQASDDHSSEIHSAN*GET APQAAKFLWLRSSRIRGGKI**KPP*KDS*ARW NTNSILL*KSQNQHSSDQAKCVHLQQAPIGS*GP KKHLGVSFDTV*RRCD*SRSIHSGTSL*DQGVH HQ*YPQTFPGGTPQPGSSNPGISGFSWQSYGAF E*CF*RGYWTDKIWKCRGPHQKCYTRSIKLCCQV CWNIIRWLREDDGQSASVRAGVHQVPCSHKW*T PCSRHPWPGSWYHWWTDQCYNFDSGRCENRRGC QRFHIWPWKRACWHCNQASGRRPGFCIRNSPGGE RHSHTQRPQDSSTEGSETALLHGAPGAASPIF* EPGGRTGAALQTHRQHTGRILHRCGEH*QLLRA HLLQSCLLPEKWRLRGSRSHFPRSQIR*PLPLPC LQRPWEGVCAGDQESREHEQWSVHPRPLPPEAH GPCEI*GPCCQVVTRNKLRKEPLL*TAAYVKTQ RKPRAAGAGLLKPRC*DGRSRHSADPPGGKRPSS QLTMEAEPESGLGKLSRNEGK*ILMRKSTNGNR INL*GRELF*IMGNNF*RYWLNNV*KHVLR*I* FLDCPVFC*HVYMYNSVFVNI*ERF*TGSVLCVK VC*L*SNIKLYWIFYCTNSRCLIQDTVYRKAFL KVKECYVLVLETKVFPVKWVEVRAVVLKGTPLT SWLSSWAVSCGTQDWRWPFRRI*ERGLGAHF*FL TPILQRVLRFLQIMM*VIHLAFS*LVLPNLGGN LCSITTWVQVSIVSFLRLLLLERLETLVNSVD* EGKKKSH*TVATNQKST*KCSPAWAATTKNKAPG LFSF**SHRQAS*LHSPRGHRMETPG*EGSRES SRKGDEIGVLKSCVGKFFMEPRFDKGISYPWF* IPAGSKAWYERPGSCFWCFAFL*GLSR*GEGKRG LTLE*MSHLVIFKFLF**S*SISTTLSHVAESG MTQWISGCVEGFGVYNS*PKSFQDTNEANLLPL PFLSHFPSVSVSVCVCVCVCVRARACMQRGRKGA LAQVAT*CSRISFLELRGLVAFAELQVSGLQNG NLAFAALGEF*FVCVLLGGGDDCLSTHALHKMA AGYSTAQDGSSSAASSSASLLAPPQVWLVVFVIS NLLPEIMIS*KMRLSEGLIVCVSEPSITFWNKV T*NLLMRLRSLVLLRKSALGRSSAGCSQT*LRK LAAGCPVGWCFRRNPEKCSDAPLGLLSNFNQLFK *LPISCDCTTKHFDICTLGEADVKMESKDHLGR GWVGDGRANCELLHFSALPCPAALGQTRPEGFR GI*HPLLVLTRKTSKALEETGPAPGSLNAPSLCK LIFSQQCLRLC*DHFYCFSFCFKHTVRL*GK*N KWNKSKLGKEISKATQSLDPAQLADPCHSLAVA ASLCSLKGEPGQCFPSPWAWSLHSGKQTSGPFPK SQECLAAWWVLIAMF*RLQGHFVCKYDLGLKIP **LLDKILKISGSLLCKHYYSHQCVKTLESGSH IRVIIFLPVE*NALWTSQ

Sequence NM_015378

AGGAGCGGCGGGGAGGAAACGCCGCGCAGCGCCGGGCTGGGGCGGGCGGCCCGGGACACCGACAGATTTTTCTGTGACCATGAAAGAGAGAAATAAAGAA TGATCCATGATTTCTAAACACCTTTTCCTGAGGATATAGTCATGTTGGAAGGCCTTGTAGCCTGGGTTCTCAATACCTATTTGGGAAAATATGTCAATAA CCTGAACACTGACCAGCTCTCAGTTGCACTTCTCAAAGGTGCTGTTGAATTAGAAAACTTGCCATTAAAGAAAGATGCCTTGAAAGAATTGGAATTACCA TTTGAAGTCAAAGCTGGCTTCATTGGGAAAGTAACCCTTCAGATTCCCTTTTATCGCCCCCATGTGGACCCTTGGGTGATCTCCATCTCCAGCCTTCACT TAATTGGAGCCCCAGAGAAAATACAGGATTTCAATGATGAAAAGGAGAAGCTGTTGGAAAGGGAACGTAAGAAAGCACTACTTCAAGCCCTGGAGGAGAA ATGGAAGAATGACCGCCAGCAGAAAGGGGAGTCCTATTGGTATTCAGTTACCGCCTCCGTAGTTACAAGGATTGTGGAGAATATTGAATTAAAAATTCAA GATGTCCATTTACGCTTTGAAGATGGTGTCACCAATCCCTCCCATCCTTTTGCTTTTGGCATCTGCATTAAGAATGTGTCCATGCAAAATGCTGTGAATG AGCCTGTACAGAAACTAATGCGGAAAAAGCAATTAGACGTAGCAGAATTTAGCATCTATTGGGATGTCGATTGCACTTTACTGGGGGATTTGCCTCAGAT GGAGTTACAGGAGGCCATGGCCAGGAGCATGGAGAGTCGCAGCCATCACTACGTCCTGGAGCCTGTGTTTGCATCTGCTCTTTTGAAGAGAAACTGCTCC AAGAAGCCCCTGCGGTCTCGGCACAGTCCCCGTATTGATTGTGATATTCAGCTGGAGACCATTCCCTTGAAACTCTCTCAGCTGCAATACCGGCAAATCA TGGAATTCCTCAAGGAGCTGGAACGAAAGGAGAGGCAGGTGAAGTTCCGAAGGTGGAAACCCAAGGTGGCGATATCTAAGAACTGCCGAGAATGGTGGTA TTTTGCTTTGAATGCTAACTTGTATGAGATCAGAGAGCAGAGGAAACGTTGCACCTGGGACTTTATGTTGCACCGCGCTCGTGATGCTGTATCTTACACT GACAAATATTTCAACAAGTTAAAAGGAGGCCTGCTGTCCACAGATGACAAGGAGGAAATGTGTCGGATTGAAGAGGAACAGAGCTTTGAGGAATTGAAGA TTTTGCGTGAACTGGTTCATGATCGATTTCACAAACAGGAAGAACTAGCAGAGAGTCTGCGGGAGCCTCAGTTTGATTCTCCAGGAGCCTGTCCGGGAGC CCCAGAACCCGGTGGAGGCAGTGGGATGCTGCAGTATCTCCAGTCCTGGTTTCCTGGATGGGGTGGCTGGTACGGGCAGCAGACCCCAGAAGGGAATGTG GTTGAGGGACTGTCAGCAGAGCAACAGGAGCAGTGGATTCCTGAAGAGATCCTGGGCACTGAGGAGTTTTTTGACCCCACTGCAGATGCCTCGTGTATGA ACACGTATACAAAGCGAGATCATGTCTTTGCCAAACTGAATTTGCAGTTGCAGCGAGGTACAGTGACTCTGTTACACAAGGAGCAAGGAACTCCTCAAAT GAATGAAAGTGCTTTCATGCAGCTCGAGTTTTCAGATGTAAAACTTCTAGCAGAGTCTCTTCCTCGAAGAAATTCCTCGTTGCTTTCAGTCCGGTTGGGT GGACTGTTTCTTCGAGACCTGGCTACAGAAGGAACTATGTTTCCTCTTCTAGTCTTCCCTAATCCACAAAAAGAAGTTGGCAGAGTCTCACAATCTTTTG GTCTACAAACTACATCTGCAGACAGAAGTGATCATTACCCAGCTGCAGATCCAGATGGCCCCGTTTTTGAGATGCTGTATGAGAGAAATCCGGCGCACAG CCACTTTGAGAGGCGGCTCAATGTCAGCACAAGGCCCTTGAACATCATATACAATCCGCAGGCCATTAAAAAAGTAGCAGACTTTTTCTACAAGGGAAAG GTTCATACCTCAGGTTTTGGTTATCAGTCTGAACTTGAGCTGAGAGTGGCTGAAGCTGCCCGAAGACAATATAACAAGCTGAAGATGCAGACCAAGGCAG AAATCCGGCAAACTCTTGATCGTTTGCTAGTGGGTGATTTCATTGAGGAGAGTAAACGATGGACCGTGCGGCTGGATATTTCTGCCCCTCAGGTGATATT TCCTGATGATTTCAAATTCAAGAATCCTGTGTTAGTTGTCGTGGATCTAGGAAGAATGCTTTTGACGAACACCCAAGATAACTCCAGGAGGAAAAGTAGG GATGGGTCAGCATCTGAAGAGACCCAGTTTAGTGATGATGAATATAAGACCCCCCTGGCCACACCTCCTAACACCCCACCTCCCGAGTCAAGCAGCAGCA ACGGAGAGAAAACACCTCCCTTTTCTGGAGTTGAGTTCAGTGAAGAACAGCTTCAAGCACATTTAATGAGCACAAAGATGTATGAGAGGTACTCGCTGTC ATTTATGGACCTCCAGATCATGGTTGGACGAGTGAAAGACAATTGGAAGCATGTCCAGGATATTGACGTGGGACCAACACATGTGGTAGAGAAGTTCAAC GTTCACCTACAGTTAGAGCGTCGATTGATTTATACTTCAGATCCCAAATATCCAGGAGCCGTGCTCTCAGGCAACTTACCAGACTTAAAAATCCACATTA ATGAAGATAAAATATCTGCACTAAAGAATTGCTTTGCTCTCCTCACCACCCCAGAAATGAAAACTTCTGACACTCAGATTAAAGAAAAGATTTTTCCCCA GGAGGAGCAGCGGGGAAGTTTGCAAGACTCCGTAATGAATTTAACCCAGAGCATTGTGTTGTTGGAGCAGCATACCCGCGAGGTTCTGGTGGAGTCGCAG CTCCTCCTGGCGGAATTTAAAGTGAACTGTATGCAGCTTGGTGTTGAGAGCAATGGCCGGTACATTTCTGTGCTCAAGGTGTTTGGTACCAATGCTCACT TTGTGAAGAGGCCTTATGATGCTGAAGTCTCCCTAACTGTTCATGGTTTGCTCCTGGTGGATACCATGCAGACATATGGTGCTGATTTTGACCTTTTGAT GGCTTCACATAAGAACTTGAGCTTTGATATTCCAACGGGAAGCCTTCGGGATAGCAGGGCCCAGTCTCCTGTCTCTGGACCGAATGTGGCCCACTTAACT GATGGAGCTACACTGAACGACCGATCAGCTACTAGTGTTTCACTTGACAAAATTCTTACCAAAGAGCAAGAGTCCCTTATTAAGTTGGAATATCAGTTTG TGAGTTCAGAGTGCCCATCGATGAATTTAGACAGTACTCTTCAGGTGATTTCCCTACAGGTGAATAATTTAGATATTATCCTCAATCCAGAGACGATTGT GGAGCTAATTGGTTTTCTTCAAAAATCCTTTCCCAAGGAAAAAGATGATTTAAGTCCTCAACCTTTAATGACTGATTTTGAAAGAAGCTTCAGAGAACAA GGAACTTACCAGTCTACATATGAACAAAACACTGAGGTTGCAGTGGAAATCCATAGGCTGAACTTACTGCTTCTTCGGACAGTGGGCATGGCAAATAGAG AGAAATATGGCAGAAAAATTGCAACTGCAAGTATAGGTGGCACCAAAGTTAATGTCTCAATGGGTAGCACGTTTGACATGAATGGTTCTCTTGGCTGTTT ACAGCTTATGGATTTGACACAAGATAACGTTAAAAACCAGTATGTTGTCAGCATTGGGAATTCTGTAGGCTATGAAAATATCATCAGTGATATTGGCTAC TTTGAATCTGTGTTTGTCAGAATGGAAGATGCAGCCCTCACTGAAGCTTTGAGTTTCACGTTTGTTGAGAGATCTAAACAGGAGTGTTTTCTCAACCTGA AGATGGCTTCTTTACATTATAACCACTCTGCTAAGTTTTTGAAGGAGTTGACGTTATCCATGGATGAACTGGAAGAAAATTTTCGAGGTATGCTGAAAAG CGCAGCCACCAAAGTCACCACAGTACTAGCTACCAAGACTGCCGAGTATAGCGAGATGGTATCGCTCTTTGAAACTCCAAGGAAGACTCGGGAACCCTTT ATCTTAGAGGAAAATGAAATATATGGGTTTGACCTAGCTTCGTCTCATTTGGACACTGTAAAGCTAATCTTGAACATAAACATTGAATCACCAGTTGTTT CTATCCCTCGGAAGCCGGGGAGTCCTGAGTTGTTGGTGGGACACTTGGGACAGATATTCATCCAGAATTTTGTGGCGGGAGATGATGAATCCAGAAGTGA CCGTCTGCAGGTGGAAATCAAGGACATTAAACTGTATTCTTTGAATTGCACCCAGTTGGCAGGTAGAGAAGCTGTTGGGTCTGAAGGAAGCCGGATGTTT TGCCCACCTTCCGGGTCTGGCAGTGCCAACAGTCAGGAGGAAGCTCATTTCACACGACATGATTTCTTTGAATCTTTGCATAGAGGTCAAGCTTTTCACA TCCTGAACAACACCACCATTCAGTTTAAACTGGAGAAGATCCCTATAGAGAGAGAATCTGAATTGACTTTTTCTCTTAGCCCAGATGACCTGGGAACTTC TAGCATCATGAAGATTGAAGGAAAATTTGTCAATCCAGTTCAGGTGGTGTTAGCAAAGCATGTATATGAGCAGGTTTTACAAACCCTGGACAATCTCGTG TACAGTGAAGATCTGAATAAGTATCCAGCCAGTGCTACCTCCTCCCCTTGCCCTGATTCTCCTCTGCCTCCCCTCAGTACCTGTGGAGAATCTTCTGTTG AAAGGAAGGAGAATGGATTGTTCAGCCACTCCAGCCTTTCTAACACCTCTCAGAAGTCATTGTCAGTGAAGGAAGTCAAATCCTTTACTCAGATTCAAGC CACCTTTTGTATATCAGAGCTTCAGGTTCAGCTAAGTGGAGATCTGACTTTGGGGGCCCAAGGTCTTGTGAGCTTAAAGTTTCAGGACTTTGAGGTGGAA TTCAGTAAAGACCATCCCCAGACTTTATCTATTCAGATTGCCCTGCATTCTCTGCTGATGGAGGACTTATTGGAGAAGAATCCAGATTCTAAATATAAGA ACCTGATGGTGTCTCGAGGAGCCCCTAAGCCATCTAGTTTAGCACAAAAAGAATACCTTTCTCAGTCTTGCCCCTCAGTGTCCAATGTGGAATATCCTGA TATGCCTCGGTCTCTCCCTTCCCACATGGAAGAAGCTCCTAATGTCTTCCAGTTGTATCAAAGGCCCACCTCTGCGTCCCGGAAAAAGCAAAAGGAAGTC CAAGACAAGGACTATCCCTTGACCCCACCTCCTTCTCCAACAGTGGATGAGCCCAAGATACTTGTTGGAAAGAGTAAATTTGATGATTCCTTAGTCCACA TCAACATATTCTTGGTAGATAAGAAACATCCAGAATTCTCTTCCAGTTACAATCGAGTTAACCGGAGCATTGATGTTGATTTTAATTGCTTGGATGTGCT GATCACACTGCAAACCTGGGTTGTGATATTAGACTTTTTTGGAATCGGCTCCACTGCAGACAACCACGCAATGAGGCTGCCTCCTGAGGGCATTCTGCAC AACGTGAAGTTGGAGCCACATGCCTCCATGGAGTCTGGACTTCAGGATCCAGTGAACACCAAACTGGATCTCAAGGTTCATTCACTTTCTCTAGTGCTGA ATAAGACCACCAGTGAGCTTGCCAAAGCAAATGTGTCCAAATTAGTAGCACACCTGGAAATGATTGAGGGAGACCTGGCCTTACAGGGCAGCATTGGGAG TCTGTCTCTAAGTGACCTCACATGCCATGGAGAGTTCTACAGAGAACGGTTCACTACCAGTGGTGAAGAAGCACTCATCTTCCAGACTTTTAAATACGGA CGGCCTGACCCTCTGCTCCGGAGAGAACACGACATTCGCGTGAGCCTCCGGATGGCCTCTGTGCAGTATGTGCATACTCAGCGTTTCCAGGCAGAGGTGG TGGCCTTCATTCAGCATTTCACTCAGCTGCAGGATGTCTTAGGGCGCCAGCGAGCTGCTATTGAGGGGCAGACGGTGAGAGATCAAGCCCAGCGCTGTTC ACGGGTTCTCCTGGATATTGAGGCTGGTGCTCCCGTTCTCTTGATCCCAGAAAGTTCCAGATCAAATAATCTGATTGTAGCAAATTTGGGGAAGTTGAAA GTCAAAAATAAGTTTCTGTTTGCTGGTTTTCCTGGCACCTTTTCCCTACAAGATAAGGAATCTGTGCCTTCAGCTTCCCCAACGGGTATTCCCAAACACA GTCTGAGGAAAACGACAAGCACGGAGGAGCCCAGGGGAACCCATTCCCAGGGGCAGTTCACGATGCCTCTTGCTGGAATGAGCCTAGGAAGCCTGAAGAG TGAGTTTGTGCCCAGTACCTCCACCAAGCAGCAAGGGCCGCAACCCACACTGTCTGTTGGCCAAGAGTCCAGTAGTCCAGAAGACCATGTCTGCCTGCTG GATTGCGTTGTCGTGGATCTCCAGGACATGGACATCTTTGCTGCAGAGAGACATCCGAGAGAATACTCGAAGGCACCAGAGGATAGTAGTGGAGATCTGA TCTTCCCTTCCTATTTTGTGCGACAGACAGGAGGAAGCCTCTTAACCGAGCCTTGTAGGCTGAAATTGCAGGTGGAAAGGAATTTGGACAAAGAAATAAG TCATACTGTGCCAGACATATCTATCCATGGCAATCTCTCCTCAGTCCACTGCTCTCTGGATCTGTATAAATACAAGCTGATCCGCGGCTTATTAGAGAAC AACCTGGGAGAACCCATAGAGGAATTTATGCGGCCTTATGATTTACAAGATCCAAGAATTCATACTGTCCTGAGTGGAGAAGTGTACACCTGTATGTGCT TCCTCATTGATATGGTGAATGTAAGTCTGGAGCTTAAAGATCCAAAAAGAAAAGAAGGTGCTGGGTCCCTAGCCAGATTTGACTTCAAGAAATGCAAACT GCTCTATGAAAGTTTTTCCAACCAAACCAAGTCCATTAACTTGGTTTCCCATTCCATGATGGCTTTTGACACCCGTTATGCTGGGCAGAAGACCAGCCCT GGCATGACGAATGTGTTCAGCTGTATCTTTCAGCCCGCTAAGAACAGCAGCACCACCCAAGGGTCCATTCAGATTGAACTACATTTCAGATCTACCAAGG ATTCCTCCTGCTTTACAGTAGTTCTCAACAATCTCCGTGTGTTTCTCATATTTGACTGGCTACTGTTAGTCCATGATTTTCTCCACACTCCCAGTGATAT TAAGAAACAAAATCATGTTACTCCTTCTCGCCACCGTAACTCTAGCAGCGAATCTGCTATAGTTCCCAAAACTGTGAAGAGTGGAGTAGTTACCAAGCGG TCTTCCCTTCCTGTGTCCAATGAAAGGCACCTGGAGGTCAAGGTCAATGTAACAGGTACGGAGTTTGTGGTCATTGAAGATGTGTCCTGCTTCGACACCA ATGCCATTATTCTGAAAGGCACCACAGTGCTCACCTATAAGCCCCGGTTTGTTGATCGCCCCTTTTCAGGAAGTTTGTTTGGCATTGAGGTGTTTTCATG CCGACTAGGGAATGAGCATGATACAGCTCTTTCAATTGTGGATCCCGTACAAATTCAAATGGAGTTGGTGGGGAATTCTTCTTATCAAAATAGTTCAGGA TTGATGGATGCATTCAATAGTGAAGATTTCCCACCTGTCCTGGAGATTCAGTTACAAGCCCTGGATATCAGACTCTCCTATAATGATGTTCAGCTGTTTC TTGCCATTGCAAAATCCATCCCAGAGCAAGCTAATGCTGCAGTGCCAGACTCAGTGGCCCTGGAGTCAGACTCCGTTGGCACTTACCTTCCAGGTGCATC TCGCGTTGGAGAGGAAATCAGAGAAGGGACAAGACACACCTTAGATCCTGTCTTGGAGTTACAGCTGGCTAGGCTGCAGGAGCTGGGATTCAGCATGGAT GATTGTCGCAAAGCTCTTTTGGCGTGTCAAGGCCAATTGAAAAAGGCAGCAAGTTGGTTGTTTAAGAATGCGGAACCTCTGAAGTCTCTTTCCTTGGCCT CCACCAGCCGAGATAGCCCAGGGGCTGTGGCAGCGCCATTGATCTCTGGCGTGGAGATCAAAGCTGAGAGTGTGTGCATCTGTTTCATCGATGACTGCAT GGATTGTGATGTTCCTCTCGCTGAACTCACCTTTTCCCGTCTGAATTTTCTTCAGCGTGTAAGAACTAGCCCTGAAGGCTATGCCCACTTCACCCTTTCT GGAGATTATTATAACCGTGCTCTTTCAGGCTGGGAGCCATTTATTGAGCCTTGGCCATGCTCTGTATCCTGGCAACAGCAGGCAGCTAGTCGTCTCCATC CTCCTCGACTGAAGCTAGAAGCCAAGGCCAAACCTCGTTTGGATATCAATATCACTTCTGTGCTAATTGACCAGTATGTAAGTACCAAGGAATCGTGGAT GGCAGATTACTGTAAAGATGACAAGGACATAGAGTCAGCTAAATCAGAAGACTGGATGGGCTCTTCGGTGGATCCTCCATGTTTTGGACAAAGCCTCCCC CTTGTCTACCTTAGAACTAGGAGTACAGCCAGTCTGACTAACCTAGAGCACCAGATCTATGCTAGAGCAGAGGTGAAAACCCCCAAGCGCCGGCAGCCAT TTGTCCCCTTTGCTCTGAGGAACCACACGGGGTGCACTTTGTGGTTTGCCACCCTGACCACCACACCCACCAGAGCTGCACTCTCTCACAGTGGGAGTCC AGGGGTAGTTCCAGAAGGGAACGGAACATTTCTCGATGATACTCACAATGTTAGTGAATGGCGAGAAGTCCTTACAGGTGAAGAGATTCCCTTTGAATTT GAAGCAAGAGGAAAGTTAAGACACAGACACACCCATGACCTCCGGATTCATCAACTGCAAGTGAGAGTAAATGGCTGGGAGCAAGTGAGCCCAGTGTCTG TGGACAAAGTCGGGACCTTTTTTCGATATGCAGCACCAGATAAAAATTCATCTTCCTCTACGATTGGCAGCCCAAGCAGCAGAACAAATATTATACATCC CCAGGTTTATTTCTCTTCACTCCCACCAGTGCGGGTGGTCTTTGCAGTGACTATGGAAGGCAGTGCACGGAAAGTCATCACTGTCCGGTCAGCCCTCATT GTGAGGAACAGACTTGAGACACCAATGGAACTAAGACTGGATAGCCCATCAGCTCCAGACAAGCCAGTGGTGCTTCCTGCTATCATGCCAGGGGATTCGT TTGCTGTGCCTTTACACCTCACTTCTTGGCGGCTACAGGCCCGGCCCAAAGGATTGGGTGTATTTTTCTGTAAGGCTCCCATTCATTGGACCAATGTAGT GAAGACTGCAGAAATTAGTAGCAGTAAACGAGAGTGCCACTCTATGGACACAGAAAAAAGCCGATTTTTCAGGTTTTGTGTGGCTATAAAGAAAGAGAAT TATCCAGATTATATGCCCTCAAACATATTTTCTGACAGTGCAAAACAGATTTTCAGACAGCCTGGGCATACCATATATCTCCTGCCAACTGTGGTAATCT GCAACTTGCTACCCTGTGAACTTGATTTTTATGTTAAAGGAATGCCAATTAATGGGACGCTGAAACCTGGCAAGGAGGCAGCTCTCCATACAGCTGATAC ATCCCAGAACATTGAGCTGGGGGTATCACTGGAGAATTTCCCCCTCTGTAAAGAATTGCTCATTCCACCTGGAACCCAAAACTATATGGTGAGAATGCGA CTCTATGACGTCAACCGTCGGCAGCTGAACCTCACCATCCGGATTGTGTGTCGAGCAGAAGGATCCTTAAAGATCTTCATTTCTGCTCCATATTGGCTGA TTAACAAAACAGGGTTGCCACTGATCTTCAGACAGGACAATGCCAAGACAGATGCTGCAGGCCAGTTTGAGGAGCATGAGCTGGCCCGTAGCCTGAGTCC TCTCTTATTCTGCTATGCTGACAAAGAGCAGCCAAACCTCTGCACGATGAGAATCGGAAGGGGGATTCATCCAGAAGGCATGCCGGGCTGGTGTCAGGGC TTCTCCCTGGATGGTGGTAGTGGTGTCCGAGCTTTGAAAGTCATCCAGCAAGGAAACCGCCCAGGGCTGATCTATAACATTGGTATTGATGTCAAGAAAG GCCGAGGTCGATACATTGATACCTGCATGGTCATCTTTGCCCCCCGTTACCTGTTAGATAATAAATCATCTCACAAGCTTGCATTTGCACAGAGGGAATT TGCCAGGGGACAGGGAACAGCCAATCCCGAAGGTTACATTTCCACCCTTCCTGGTTCCAGTGTGGTGTTCCACTGGCCTCGGAATGACTATGATCAGCTA TTGTGTGTCAGACTGATGGACGTTCCCAATTGTATTTGGTCTGGAGGCTTTGAAGTCAACAAGAATAATTCCTTCCATATCAACATGAGGGATACCTTGG GAAAATGCTTCTTCCTACGAGTGGAAATTACTCTCCGAGGAGCTACGTATAGGATCTCATTTAGTGACACAGATCAGTTACCTCCTCCTTTCCGAATTGA CAACTTTTCTAAGGTCCCGGTTGTCTTTACTCAGCATGGCGTAGCTGAACCCAGGCTCCGGACTGAAGTGAAGCCCATGACTTCATTGGATTATGCCTGG GACGAACCCACCTTGCCACCTTTTATCACTCTGACTGTTAAAGGGGCAGGGTCCTCTGAGATCAACTGCAACATGAATGATTTCCAGGATAATCGGCAGC TTTATTATGAAAATTTCATTTACATTGCTGCTACATATACATTCTCTGGCTTGCAGGAGGGAACAGGCAGGCCTGTGGCTTCCAACAAGGCCATTACCTG TGCGGAGCTCGTTTTGGATGTCTCACCCAAGACACAAAGAGTCATTTTAAAAAAGAAGGAACCAGGAAAGCGTTCTCAGCTGTGGAGGATGACAGGAACA GGAATGCTGGCCCATGAGGGCTCCTCAGTTCCTCACAATCCCAATAAGCCCTCAGCCGCCCGCTCCACCGAGGGGTCTGCCATCTTAGATATTGCTGGTC TCGCTGCAGTGACTGACAACAGATACGAGCCACTGATGCTGAGAAAGCCTGACCGCAGGCGAAGCACAACTCAGACGTGGAGTTTCCGAGAAGGAAAACT GACCTGTGGGTTACATGGGTTGGTCGTCCAGGCCAAAGGAGGACTTTCTGGTTTGTTTGATGGAGCTGAAGTTGTTCTTGGTCCTGACACTTCCATGGAG CTTTTGGGGCCAGTTCCACCTGAACAACAATTTATTAATCAAAAAATGAGACCTGGTTCTGGAATGTTATCCATCAGAGTCATCCCAGATGGACCAACTA GAGCACTCCAGATAACAGATTTCTGCCACCGGAAAAGCAGCCGTTCATATGAAGTGGATGAACTTCCTGTCACCGAACAAGAGCTGCAGAAATTAAAGAA TCCAGATACAGAGCAGGAATTGGAAGTGCTTGTGAGGTTAGAAGGTGGAATTGGGTTGTCCTTAATTAATAAAGTCCCAGAAGAACTGGTCTTTGCAAGT CTTACAGGAATCAATGTGCACTATACACAGCTGGCAACCAGTCACATGCTTGAACTCAGCATACAGGATGTACAGGTGGACAATCAGCTCATTGGTACCA CGCAGCCCTTCATGCTCTATGTGACTCCCCTGAGCAATGAGAATGAGGTCATCGAGACCGGCCCAGCTGTGCAAGTCAACGCAGTGAAGTTCCCCAGTAA GAGTGCACTGACCAACATCTACAAGCATCTGATGATCACAGCTCAGAGATTCACAGTGCAAATTGAGGAGAAACTGCTCCTCAAGCTGCTAAGTTTCTTT GGCTACGATCAAGCAGAATCAGAGGTGGAAAAATATGATGAAAACCTCCATGAAAAGACAGCTGAGCAAGGTGGAACACCAATTCGATACTACTTTGAAA ATCTCAAAATCAGCATTCCTCAGATCAAGCTAAGTGTGTTCACCTCCAACAAGCTCCCATTGGATCTTAAGGCCCTAAAAAGCACCTTGGGGTTTCCTTT GATACGGTTTGAAGACGCTGTGATTAATCTAGATCCATTCACTCGGGTACATCCCTATGAGACCAAGGAGTTCATCATCAATGATATCCTCAAACATTTC CAGGAGGAACTCCTCAGCCAGGCAGCTCGAATCCTGGGATCAGTGGATTTTCTTGGCAATCCTATGGGGCTTTTGAATGATGTTTCTGAAGGGGTTACTG GACTGATAAAATATGGAAATGTCGGGGGCCTCATCAGAAATGTTACACACGGAGTATCAAACTCTGCTGCCAAGTTTGCTGGAACATTATCAGATGGCTT AGGGAAGACGATGGACAATCGGCATCAGTCAGAGCGGGAGTACATCAGGTACCATGCAGCCACAAGTGGTGAACACCTTGTAGCCGGCATCCATGGCCTG GCTCATGGTATCATTGGTGGACTGACCAGTGTTATAACTTCGACAGTGGAAGGTGTGAAAACAGAAGGGGGTGTCAGCGGTTTCATATCTGGCCTTGGAA AAGGGCTTGTTGGCACTGTAACCAAGCCAGTGGCAGGCGCCCTGGATTTTGCATCAGAAACAGCCCAGGCGGTGAGAGACACAGCCACACTCAGCGGCCC CAGGACTCAAGCACAGAGGGTTCGGAAACCGCGTTGCTGCACGGGGCCCCAGGGGCTGCTTCCCCGATATTCTGAGAGCCAGGCGGAAGGACAGGAGCAG CTCTTCAAACTCACAGACAACATACAGGACGAATTCTTCATCGCTGTGGAGAACATTGACAGCTACTGCGTGCTCATCTCCTCCAAAGCTGTTTACTTCC TGAAAAGTGGAGACTACGTGGATCGAGAAGCCATTTTCCTAGAAGTCAAATACGATGACCTCTACCACTGCCTTGTCTCCAAAGACCATGGGAAGGTGTA TGTGCAGGTGACCAAGAAAGCCGTGAGCACGAGCAGTGGAGTGTCCATCCCCGGCCCCTCCCACCAGAAGCCCATGGTCCATGTGAAATCTGAGGTCCTT GCTGTCAAGTTGTCACAAGAAATAAACTACGCAAAGAGCCTCTACTATGAACAGCAGCTTATGTTAAGACTCAGCGAAAACCGAGAGCAGCTGGAGCTGG ACTCCTGAAGCCCCGCTGCTGAGATGGGCGCTCCCGACACAGCGCAGACCCACCAGGAGGAAAGAGGCCCAGCTCTCAGCTGACGATGGAGGCAGAACCG GAGTCGGGTTTGGGGAAGTTGTCAAGGAATGAGGGAAAGTAAATCCTCATGAGGAAAAGTACAAATGGAAATCGTATTAATTTGTGAGGCAGGGAGTTAT TTTAGATTATGGGAAATAATTTTTAAAGGTATTGGTTAAATAACGTTTAAAAACATGTACTGAGATGAATCTAATTTTTAGATTGCCCTGTATTTTGTTA ACATGTATATATGTACAACAGTGTGTTTGTAAATATATAGGAACGTTTCTGAACAGGGTCTGTGCTATGTGTAAAGGTTTGTTAACTGTAAAGTAATATA AAGTTATATTGGATCTTCTATTGCACTAATTCTAGATGTCTAATTCAGGATACTGTCTATAGAAAGGCATTCTTAAAAGTTAAAGAATGTTACGTCTTAG TTTTGGAGACTAAAGTATTCCCAGTAAAGTGGGTTGAGGTGAGGGCTGTGGTCCTGAAAGGGACGCCTTTGACATCGTGGCTGTCCAGTTGGGCTGTGAG CTGTGGCACCCAGGACTGGCGCTGGCCCTTCAGAAGGATCTAGGAGAGGGGCTTGGGAGCCCACTTTTAATTTCTCACCCCCATTTTACAAAGAGTGCTT AGATTCTTACAAATTATGATGTAAGTTATCCATTTGGCTTTTTCCTAACTAGTCTTACCAAACTTAGGGGGAAACCTGTGCTCCATTACCACATGGGTGC AAGTCAGCATTGTAAGTTTTCTCAGGTTATTATTATTAGAGAGGTTGGAAACATTGGTAAACTCTGTTGATTGAGAAGGAAAAAAAAAGTCCCATTGAAC TGTTGCAACAAATCAGAAATCCACATAAAAGTGCTCTCCTGCCTGGGCAGCAACAACCAAGAACAAAGCCCCGGGACTGTTTTCTTTTTAATAAAGCCAC AGGCAGGCATCGTAGCTCCACAGCCCGAGGGGACACAGGATGGAAACCCCAGGATGAGAAGGGAGCAGGGAGAGTTCCAGAAAGGGGGATGAAATAGGAG TATTAAAAAGCTGCGTTGGTAAGTTTTTCATGGAACCAAGATTTGACAAAGGCATCTCTTATCCTTGGTTTTAAATTCCTGCTGGGAGCAAGGCCTGGTA TGAGCGCCCTGGGTCTTGTTTTTGGTGTTTCGCTTTTCTGTAAGGATTAAGCAGATAGGGAGAAGGGAAAAGGGGCCTCACTTTAGAATGAATGAGTCAC CTTGTGATTTTTAAATTTTTATTTTAATAAAGCTAATCAATTTCTACAACCTTGTCACATGTAGCTGAGTCTGGGATGACTCAGTGGATCAGTGGATGCG TGGAAGGTTTTGGTGTTTATAACTCATGACCCAAATCCTTCCAAGACACAAATGAAGCTAATCTTCTTCCCCTCCCTTTCCTCTCCCACTTCCCCTCTGT GTCTGTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGCGCGTGCATGCAGAGAGGAAGGAAGGGAGCTTTAGCACAAGTAGCTACATAGTGT TCAAGGATCAGCTTTCTTGAACTCCGAGGCTTGGTTGCCTTTGCTGAACTCCAAGTTAGTGGATTGCAGAATGGAAACTTGGCTTTTGCGGCACTGGGTG AGTTTTAGTTTGTGTGTGTCTTGCTGGGGGGTGGTGATGATTGTCTCAGCACTCACGCACTGCACAAGATGGCAGCAGGATACAGCACTGCACAAGATGG CAGCTCCTCTGCAGCTTCCTCCTCAGCCTCCCTCCTTGCACCCCCACAGGTTTGGCTTGTGGTTTTTGTCATCAGTAACCTACTGCCTGAGATCATGATC TCTTAAAAGATGAGACTCTCGGAAGGGTTGATTGTATGCGTCAGTGAGCCTTCTATCACCTTCTGGAACAAAGTCACTTGAAATCTCTTGATGAGATTAA GGAGTTTAGTGTTACTAAGAAAATCTGCTTTGGGCCGCAGCAGTGCTGGGTGTTCTCAGACCTGACTGAGGAAGTTAGCTGCGGGCTGCCCTGTGGGCTG GTGCTTCAGGAGGAATCCAGAGAAGTGTTCAGATGCCCCCCTTGGGCTCCTTTCTAATTTTAATCAGCTCTTTAAATAGCTGCCCATCTCCTGTGATTGC ACAACCAAGCACTTTGACATTTGCACCTTAGGAGAGGCAGATGTTAAAATGGAATCCAAAGACCACCTAGGGCGGGGCTGGGTGGGAGATGGGAGGGCCA ACTGCGAGCTGCTCCACTTCTCAGCTCTCCCCTGCCCTGCAGCCCTGGGCCAGACAAGGCCAGAAGGTTTCAGGGGCATTTGACATCCCCTCCTGGTTCT CACCAGGAAAACATCCAAAGCTTTGGAGGAAACAGGCCCTGCCCCTGGCTCCTTAAATGCCCCGTCTCTTTGTAAACTGATATTCAGCCAGCAATGCCTA AGACTTTGTTAAGATCATTTCTACTGCTTTTCTTTCTGCTTCAAACACACAGTTCGTCTCTGAGGAAAGTAAAATAAATGGAATAAGAGTAAATTGGGTA AGGAGATATCCAAAGCTACCCAGTCCCTTGACCCAGCACAGTTGGCCGACCCGTGTCACTCCCTGGCTGTCGCTGCTTCTCTGTGCTCACTGAAGGGTGA GCCAGGCCAGTGCTTCCCCAGCCCCTGGGCCTGGTCACTACACAGTGGAAAACAGACAAGCGGCCCCTTCCCCAAATCCCAAGAGTGTCTTGCTGCTTGG TGGGTGCTCATCGCAATGTTCTGAAGGCTCCAGGGCCACTTTGTTTGTAAGTATGATCTGGGCCTCAAAATACCATAGTAGCTGCTTGATAAAATTCTAA AAATATCTGGTTCTCTATTATGTAAACACTATTACAGTCACCAGTGTGTGAAGACTCTTGAGTCTGGTTCTCATATCAGAGTCATCATTTTTCTTCCTGT GGAATAAAATGCCTTGTGGACTTCCCAAA

refseq_VPS13D.F1 (forward primer)
refseq_VPS13D.R1 (reverse primer)
Single exon skipping

Frame 0

RSGGEETPRSAGLGRAARDTDRFFCDHEREK*R MIHDF*TPFPEDIVMLEGLVAWVLNTYLGKYVNN LNTDQLSVALLKGAVELENLPLKKDALKELELP FEVKAGFIGKVTLQIPFYRPHVDPWVISISSLH LIGAPEKIQDFNDEKEKLLERERKKALLQALEEK WKNDRQQKGESYWYSVTASVVTRIVENIELKIQ DVHLRFEDGVTNPSHPFAFGICIKNVSMQNAVN EPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQM ELQEAMARSMESRSHHYVLEPVFASALLKRNCS KKPLRSRHSPRIDCDIQLETIPLKLSQLQYRQI MEFLKELERKERQVKFRRWKPKVAISKNCREWWY FALNANLYEIREQRKRCTWDFMLHRARDAVSYT DKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELK ILRELVHDRFHKQEELAESLREPQFDSPGACPGA PEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNV VEGLSAEQQEQWIPEEILGTEEFFDPTADASCM NTYTKRDHVFAKLNLQLQRGTVTLLHKEQGTPQM NESAFMQLEFSDVKLLAESLPRRNSSLLSVRLG GLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSF GLQTTSADRSDHYPAADPDGPVFEMLYERNPAHS HFERRLNVSTRPLNIIYNPQAIKKVADFFYKGK VHTSGFGYQSELELRVAEAARRQYNKLKMQTKA EIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIF PDDFKFKNPVLVVVDLGRMLLTNTQDNSRRKSR DGSASEETQFSDDEYKTPLATPPNTPPPESSSS NGEKTPPFSGVEFSEEQLQAHLMSTKMYERYSLS FMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFN VHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHI NEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQ EEQRGSLQDSVMNLTQSIVLLEQHTREVLVESQ LLLAEFKVNCMQLGVESNGRYISVLKVFGTNAH FVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLM ASHKNLSFDIPTGSLRDSRAQSPVSGPNVAHLT DGATLNDRSATSVSLDKILTKEQESLIKLEYQF VSSECPSMNLDSTLQVISLQVNNLDIILNPETIV ELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQ GTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANR EKYGRKIATASIGGTKVNVSMGSTFDMNGSLGCL QLMDLTQDNVKNQYVVSIGNSVGYENIISDIGY FESVFVRMEDAALTEALSFTFVERSKQECFLNL KMASLHYNHSAKFLKELTLSMDELEENFRGMLKS AATKVTTVLATKTAEYSEMVSLFETPRKTREPF ILEENEIYGFDLASSHLDTVKLILNINIESPVV SIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSD RLQVEIKDIKLYSLNCTQLAGREAVGSEGSRMF CPPSGSGSANSQEEAHFTRHDFFESLHRGQAFH ILNNTTIQFKLEKIPIERESELTFSLSPDDLGTS SIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLV YSEDLNKYPASATSSPCPDSPLPPLSTCGESSV ERKENGLFSHSSLSNTSQKSLSVKEVKSFTQIQA TFCISELQVQLSGDLTLGAQGLVSLKFQDFEVE FSKDHPQTLSIQIALHSLLMEDLLEKNPDSKYK NLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPD MPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEV QDKDYPLTPPPSPTVDEPKILVGKSKFDDSLVH INIFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVL ITLQTWVVILDFFGIGSTADNHAMRLPPEGILH NVKLEPHASMESGLQDPVNTKLDLKVHSLSLVL NKTTSELAKANVSKLVAHLEMIEGDLALQGSIGS LSLSDLTCHGEFYRERFTTSGEEALIFQTFKYG RPDPLLRREHDIRVSLRMASVQYVHTQRFQAEV VAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRCS RVLLDIEAGAPVLLIPESSRSNNLIVANLGKLK VKNKFLFAGFPGTFSLQDKESVPSASPTGIPKH SLRKTTSTEEPRGTHSQGQFTMPLAGMSLGSLKS EFVPSTSTKQQGPQPTLSVGQESSSPEDHVCLL DCVVVDLQDMDIFAAERHPREYSKAPEDSSGDL IFPSYFVRQTGGSLLTEPCRLKLQVERNLDKEIS HTVPDISIHGNLSSVHCSLDLYKYKLIRGLLEN NLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMC FLIDMVNVSLELKDPKRKEGAGSLARFDFKKCKL LYESFSNQTKSINLVSHSMMAFDTRYAGQKTSP GMTNVFSCIFQPAKNSSTTQGSIQIELHFRSTK DSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDI KKQNHVTPSRHRNSSSESAIVPKTVKSGVVTKR SSLPVSNERHLEVKVNVTGTEFVVIEDVSCFDT NAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSC RLGNEHDTALSIVDPVQIQMELVGNSSYQNSSG LMDAFNSEDFPPVLEIQLQALDIRLSYNDVQLF LAIAKSIPEQANAAVPDSVALESDSVGTYLPGAS RVGEEIREGTRHTLDPVLELQLARLQELGFSMD DCRKALLACQGQLKKAASWLFKNAEPLKSLSLA STSRDSPGAVAAPLISGVEIKAESVCICFIDDCM DCDVPLAELTFSRLNFLQRVRTSPEGYAHFTLS GDYYNRALSGWEPFIEPWPCSVSWQQQAASRLH PPRLKLEAKAKPRLDINITSVLIDQYVSTKESWM ADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLP LVYLRTRSTASLTNLEHQIYARAEVKTPKRRQP FVPFALRNHTGCTLWFATLTTTPTRAALSHSGSP GVVPEGNGTFLDDTHNVSEWREVLTGEEIPFEF EARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVS VDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHP QVYFSSLPPVRVVFAVTMEGSARKVITVRSALI VRNRLETPMELRLDSPSAPDKPVVLPAIMPGDS FAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVV KTAEISSSKRECHSMDTEKSRFFRFCVAIKKEN YPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVI CNLLPCELDFYVKGMPINGTLKPGKEAALHTADT SQNIELGVSLENFPLCKELLIPPGTQNYMVRMR LYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWL INKTGLPLIFRQDNAKTDAAGQFEEHELARSLSP LLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQG FSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKK GRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREF ARGQGTANPEGYISTLPGSSVVFHWPRNDYDQL LCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTL GKCFFLRVEITLRGATYRISFSDTDQLPPPFRID NFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAW DEPTLPPFITLTVKGAGSSEINCNMNDFQDNRQ LYYENFIYIAATYTFSGLQEGTGRPVASNKAITC AELVLDVSPKTQRVILKKKEPGKRSQLWRMTGT GMLAHEGSSVPHNPNKPSAARSTEGSAILDIAG LAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKL TCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSME LLGPVPPEQQFINQKMRPGSGMLSIRVIPDGPT RALQITDFCHRKSSRSYEVDELPVTEQELQKLKN PDTEQELEVLVRLEGGIGLSLINKVPEELVFAS LTGINVHYTQLATSHMLELSIQDVQVDNQLIGT TQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSK SALTNIYKHLMITAQRFTVQIEEKLLLKLLSFF GYDQAESEVEKYDENLHEKTAEQGGTPIRYYFE NLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPL IRFEDAVINLDPFTRVHPYETKEFIINDILKHF QEELLSQAARILGSVDFLGNPMGLLNDVSEGVT GLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGL GKTMDNRHQSEREYIRYHAATSGEHLVAGIHGL AHGIIGGLTSVITSTVEGVKTEGGVSGFISGLG KGLVGTVTKPVAGALDFASETAQAVRDTATLSGP RTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQ LFKLTDNIQDEFFIAVENIDSYCVLISSKAVYF LKSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVY VQVTKKAVSTSSGVSIPGPSHQKPMVHVKSEVL AVKLSQEINYAKSLYYEQQLMLRLSENREQLEL DS*SPAAEMGAPDTAQTHQEERGPALS*RWRQNR SRVWGSCQGMRESKSS*GKVQMEIVLICEAGSY FRLWEIIFKGIG*ITFKNMY*DESNF*IALYFV NMYICTTVCL*IYRNVSEQGLCYV*RFVNCKVI* SYIGSSIALILDV*FRILSIERHS*KLKNVTS* FWRLKYSQ*SGLR*GLWS*KGRL*HRGCPVGL* AVAPRTGAGPSEGSRRGAWEPTFNFSPPFYKECL DSYKL*CKLSIWLFPN*SYQT*GETCAPLPHGC KSAL*VFSGYYY*RGWKHW*TLLIEKEKKSPIE LLQQIRNPHKSALLPGQQQPRTKPRDCFLFNKAT GRHRSSTARGDTGWKPQDEKGAGRVPERGMK*E Y*KAALVSFSWNQDLTKASLILGFKFLLGARPG MSALGLVFGVSLFCKD*ADREKGKGASL*NE*VT L*FLNFYFNKANQFLQPCHM*LSLG*LSGSVDA WKVLVFITHDPNPSKTQMKLIFFPSLSSPTSPL CLCLCVCVCVCVCARARACREEGREL*HK*LHSV QGSAFLNSEAWLPLLNSKLVDCRMETWLLRHWV SFSLCVSCWGVVMIVSALTHCTRWQQDTALHKM AAPLQLPPQPPSLHPHRFGLWFLSSVTYCLRS*S LKR*DSRKG*LYASVSLLSPSGTKSLEIS**D* GV*CY*ENLLWAAAVLGVLRPD*GS*LRAALWA GASGGIQRSVQMPPLGSFLILISSLNSCPSPVIA QPSTLTFAP*ERQMLKWNPKTT*GGAGWEMGGP TASCSTSQLSPALQPWARQGQKVSGAFDIPSWF SPGKHPKLWRKQALPLAP*MPRLFVN*YSASNA* DFVKIISTAFLSASNTQFVSEESKINGIRVNWV RRYPKLPSPLTQHSWPTRVTPWLSLLLCAH*RV SQASASPAPGPGHYTVENRQAAPSPNPKSVLLLG GCSSQCSEGSRATLFVSMIWASKYHSSCLIKF* KYLVLYYVNTITVTSV*RLLSLVLISESSFFFL WNKMPCGLPK

Frame 1

GAAGRKRRAAPGWGGRPGTPTDFSVTMKERNKE *SMISKHLFLRI*SCWKAL*PGFSIPIWENMSI T*TLTSSQLHFSKVLLN*KTCH*RKMP*KNWNYH LKSKLASLGK*PFRFPFIAPMWTLG*SPSPAFT *LEPQRKYRISMMKRRSCWKGNVRKHYFKPWRR NGRMTASRKGSPIGIQLPPP*LQGLWRILN*KFK MSIYALKMVSPIPPILLLLASALRMCPCKML*M SLYRN*CGKSN*T*QNLASIGMSIALYWGICLR WSYRRPWPGAWRVAAITTSWSLCLHLLF*RETAP RSPCGLGTVPVLIVIFSWRPFP*NSLSCNTGKS WNSSRSWNERRGR*SSEGGNPRWRYLRTAENGG ILL*MLTCMRSESRGNVAPGTLCCTALVMLYLTL TNISTS*KEACCPQMTRRKCVGLKRNRALRN*R FCVNWFMIDFTNRKN*QRVCGSLSLILQEPVRE PQNPVEAVGCCSISSPGFLDGVAGTGSRPQKGMW LRDCQQSNRSSGFLKRSWALRSFLTPLQMPRV* TRIQSEIMSLPN*ICSCSEVQ*LCYTRSKELLK *MKVLSCSSSFQM*NF*QSLFLEEIPRCFQSGWV DCFFETWLQKELCFLF*SSLIHKKKLAESHNLL VYKLHLQTEVIITQLQIQMAPFLRCCMREIRRT ATLRGGSMSAQGP*TSYTIRRPLKK*QTFSTRER FIPQVLVISLNLS*EWLKLPEDNITS*RCRPRQ KSGKLLIVC*WVISLRRVNDGPCGWIFLPLR*Y FLMISNSRILC*LSWI*EECF*RTPKITPGGKVG MGQHLKRPSLVMMNIRPPWPHLLTPHLPSQAAA TERKHLPFLELSSVKNSFKHI**AQRCMRGTRC HLWTSRSWLDE*KTIGSMSRILTWDQHMW*RSST FTYS*SVD*FILQIPNIQEPCSQATYQT*KSTL MKIKYLH*RIALLSSPPQK*KLLTLRLKKRFFP RRSSGEVCKTP**I*PRALCCWSSIPARFWWSRS SSWRNLK*TVCSLVLRAMAGTFLCSRCLVPMLT L*RGLMMLKSP*LFMVCSWWIPCRHMVLILTF* WLHIRT*ALIFQREAFGIAGPSLLSLDRMWPT*L MELH*TTDQLLVFHLTKFLPKSKSPLLSWNISL *VQSAHR*I*TVLFR*FPYR*II*ILSSIQRRL WS*LVFFKNPFPRKKMI*VLNL**LILKEASENK ELTSLHMNKTLRLQWKSIG*TYCFFGQWAWQIE RNMAEKLQLQV*VAPKLMSQWVARLT*MVLLAV YSLWI*HKITLKTSMLSALGIL*AMKISSVILAT LNLCLSEWKMQPSLKL*VSRLLRDLNRSVFST* RWLLYIITTLLSF*RS*RYPWMNWKKIFEVC*K AQPPKSPQY*LPRLPSIARWYRSLKLQGRLGNPL S*RKMKYMGLT*LRLIWTL*S*S*T*TLNHQLF LSLGSRGVLSCWWDTWDRYSSRILWREMMNPEV TVCRWKSRTLNCIL*IAPSWQVEKLLGLKEAGCF AHLPGLAVPTVRRKLISHDMISLNLCIEVKLFT S*TTPPFSLNWRRSL*RENLN*LFLLAQMTWEL LAS*RLKENLSIQFRWC*QSMYMSRFYKPWTISC TVKI*ISIQPVLPPPLALILLCLPSVPVENLLL KGRRMDCSATPAFLTPLRSHCQ*RKSNPLLRFK PPFVYQSFRFS*VEI*LWGPKVL*A*SFRTLRWN SVKTIPRLYLFRLPCILC*WRTYWRRIQILNIR T*WCLEEPLSHLV*HKKNTFLSLAPQCPMWNIL ICLGLSLPTWKKLLMSSSCIKGPPLRPGKSKRKS KTRTIP*PHLLLQQWMSPRYLLERVNLMIP*ST STYSW*IRNIQNSLPVTIELTGALMLILIAWMC *SHCKPGL*Y*TFLESAPLQTTTQ*GCLLRAFCT T*SWSHMPPWSLDFRIQ*TPNWISRFIHFL*C* IRPPVSLPKQMCPN**HTWK*LRETWPYRAALG VCL*VTSHAMESSTENGSLPVVKKHSSSRLLNTD GLTLCSGENTTFA*ASGWPLCSMCILSVSRQRW WPSFSISLSCRMS*GASELLLRGRR*EIKPSAV HGFSWILRLVLPFS*SQKVPDQII*L*QIWGS*K SKISFCLLVFLAPFPYKIRNLCLQLPQRVFPNT V*GKRQARRSPGEPIPRGSSRCLLLE*A*EA*R VSLCPVPPPSSKGRNPHCLLAKSPVVQKTMSACW IALSWISRTWTSLLQRDIRENTRRHQRIVVEI* SSLPILCDRQEEAS*PSLVG*NCRWKGIWTKK* VILCQTYLSMAISPQSTALWICINTS*SAAY*RT TWENP*RNLCGLMIYKIQEFILS*VEKCTPVCA SSLIW*M*VWSLKIQKEKKVLGP*PDLTSRNAN CSMKVFPTKPSPLTWFPIP*WLLTPVMLGRRPAL A*RMCSAVSFSPLRTAAPPKGPFRLNYISDLPR IPPALQ*FSTISVCFSYLTGYC*SMIFSTLPVI LRNKIMLLLLATVTLAANLL*FPKL*RVE*LPSG LPFLCPMKGTWRSRSM*QVRSLWSLKMCPASTP MPLF*KAPQCSPISPGLLIAPFQEVCLALRCFH AD*GMSMIQLFQLWIPYKFKWSWWGILLIKIVQD *WMHSIVKISHLSWRFSYKPWISDSPIMMFSCF LPLQNPSQSKLMLQCQTQWPWSQTPLALTFQVH LALERKSEKGQDTP*ILSWSYSWLGCRSWDSAWM IVAKLFWRVKAN*KRQQVGCLRMRNL*SLFPWP PPAEIAQGLWQRH*SLAWRSKLRVCASVSSMTA WIVMFLSLNSPFPV*IFFSV*ELALKAMPTSPFL EIIITVLFQAGSHLLSLGHALYPGNSRQLVVSI LLD*S*KPRPNLVWISISLLC*LTSM*VPRNRG WQITVKMTRT*SQLNQKTGWALRWILHVLDKASP LSTLELGVQPV*LT*STRSMLEQR*KPPSAGSH LSPLL*GTTRGALCGLPP*PPHPPELHSLTVGV QG*FQKGTEHFSMILTMLVNGEKSLQVKRFPLNL KQEES*DTDTPMTSGFINCK*E*MAGSK*AQCL WTKSGPFFDMQHQIKIHLPLRLAAQAAEQILYI PRFISLHSHQCGWSLQ*LWKAVHGKSSLSGQPSL *GTDLRHQWN*DWIAHQLQTSQWCFLLSCQGIR LLCLYTSLLGGYRPGPKDWVYFSVRLPFIGPM* *RLQKLVAVNESATLWTQKKADFSGFVWL*RKRI IQIICPQTYFLTVQNRFSDSLGIPYISCQLW*S ATCYPVNLIFMLKECQLMGR*NLARRQLSIQLI HPRTLSWGYHWRISPSVKNCSFHLEPKTIW*ECD SMTSTVGS*TSPSGLCVEQKDP*RSSFLLHIG* LTKQGCH*SSDRTMPRQMLQASLRSMSWPVA*V LSYSAMLTKSSQTSAR*ESEGGFIQKACRAGVRA SPWMVVVVSEL*KSSSKETAQG*SITLVLMSRK AEVDTLIPAWSSLPPVTC*IINHLTSLHLHRGN LPGDREQPIPKVTFPPFLVPVWCSTGLGMTMISY CVSD*WTFPIVFGLEALKSTRIIPSIST*GIPW ENASSYEWKLLSEELRIGSHLVTQISYLLLSEL TTFLRSRLSLLSMA*LNPGSGLK*SP*LHWIMPG TNPPCHLLSL*LLKGQGPLRSTAT*MISRIIGS FIMKISFTLLLHIHSLACRREQAGLWLPTRPLP VRSSFWMSHPRHKESF*KRRNQESVLSCGG*QEQ ECWPMRAPQFLTIPISPQPPAPPRGLPS*ILLV SLQ*LTTDTSH*C*ESLTAGEAQLRRGVSEKEN *PVGYMGWSSRPKEDFLVCLMELKLFLVLTLPWS FWGQFHLNNNLLIKK*DLVLECYPSESSQMDQL EHSR*QISATGKAAVHMKWMNFLSPNKSCRN*R IQIQSRNWKCL*G*KVELGCP*LIKSQKNWSLQV LQESMCTIHSWQPVTCLNSAYRMYRWTISSLVP RSPSCSM*LP*AMRMRSSRPAQLCKSTQ*SSPV RVH*PTSTSI**SQLRDSQCKLRRNCSSSC*VSL ATIKQNQRWKNMMKTSMKRQLSKVEHQFDTTLK ISKSAFLRSS*VCSPPTSSHWILRP*KAPWGFL *YGLKTL*LI*IHSLGYIPMRPRSSSSMISSNIS RRNSSARQLESWDQWIFLAILWGF*MMFLKGLL D**NMEMSGASSEMLHTEYQTLLPSLLEHYQMA *GRRWTIGISQSGSTSGTMQPQVVNTL*PASMAW LMVSLVD*PVL*LRQWKV*KQKGVSAVSYLALE KGLLAL*PSQWQAPWILHQKQPRR*ETQPHSAA PGLKHRGFGNRVAARGPRGCFPDILRARRKDRSS SSNSQTTYRTNSSSLWRTLTATACSSPPKLFTS *KVETTWIEKPFS*KSNTMTSTTALSPKTMGRC MCR*PRKP*ARAVECPSPAPPTRSPWSM*NLRSL LSSCHKK*TTQRASTMNSSLC*DSAKTESSWSW TPEAPLLRWALPTQRRPTRRKEAQLSADDGGRT GVGFGEVVKE*GKVNPHEEKYKWKSY*FVRQGVI LDYGK*FLKVLVK*RLKTCTEMNLIFRLPCILL TCIYVQQCVCKYIGTFLNRVCAMCKGLLTVK*Y KVILDLLLH*F*MSNSGYCL*KGILKS*RMLRLS FGD*SIPSKVG*GEGCGPERDAFDIVAVQLGCE LWHPGLALALQKDLGEGLGSPLLISHPHFTKSA *ILTNYDVSYPFGFFLTSLTKLRGKPVLHYHMGA SQHCKFSQVIIIREVGNIGKLC*LRRKKKVPLN CCNKSEIHIKVLSCLGSNNQEQSPGTVFFLIKP QAGIVAPQPEGTQDGNPRMRREQGEFQKGG*NRS IKKLRW*VFHGTKI*QRHLLSLVLNSCWEQGLV *APWVLFLVFRFSVRIKQIGRREKGPHFRMNES PCDF*IFILIKLINFYNLVTCS*VWDDSVDQWMR GRFWCL*LMTQILPRHK*S*SSSPPFPLPLPLC VCVCVCVCVCVCARARVHAERKEGSFSTSSYIV FKDQLS*TPRLGCLC*TPS*WIAEWKLGFCGTG* VLVCVCLAGGW**LSQHSRTAQDGSRIQHCTRW QLLCSFLLSLPPCTPTGLACGFCHQ*PTA*DHD LLKDETLGRVDCMRQ*AFYHLLEQSHLKSLDEIK EFSVTKKICFGPQQCWVFSDLTEEVSCGLPCGL VLQEESREVFRCPPWAPF*F*SAL*IAAHLL*L HNQAL*HLHLRRGRC*NGIQRPPRAGLGGRWEGQ LRAAPLLSSPLPCSPGPDKARRFQGHLTSPPGS HQENIQSFGGNRPCPWLLKCPVSL*TDIQPAMP KTLLRSFLLLFFLLQTHSSSLRKVK*ME*E*IG* GDIQSYPVP*PSTVGRPVSLPGCRCFSVLTEG* ARPVLPQPLGLVTTQWKTDKRPLPQIPRVSCCL VGAHRNVLKAPGPLCL*V*SGPQNTIVAA**NSK NIWFSIM*TLLQSPVCEDS*VWFSYQSHHFSSC GIKCLVDFP

Frame 2

ERRGGNAAQRRAGAGGPGHRQIFL*P*KREIKN DP*FLNTFS*GYSHVGRPCSLGSQYLFGKICQ* PEH*PALSCTSQRCC*IRKLAIKERCLERIGIT I*SQSWLHWESNPSDSLLSPPCGPLGDLHLQPSL NWSPRENTGFQ**KGEAVGKGT*ESTTSSPGGE MEE*PPAERGVLLVFSYRLRSYKDCGEY*IKNS RCPFTL*RWCHQSLPSFCFWHLH*ECVHAKCCE* ACTETNAEKAIRRSRI*HLLGCRLHFTGGFASD GVTGGHGQEHGESQPSLRPGACVCICSFEEKLL QEAPAVSAQSPY*L*YSAGDHSLETLSAAIPANH GIPQGAGTKGEAGEVPKVETQGGDI*ELPRMVV FCFEC*LV*DQRAEETLHLGLYVAPRS*CCILH *QIFQQVKRRPAVHR*QGGNVSD*RGTEL*GIED FA*TGS*SISQTGRTSRESAGASV*FSRSLSGS PRTRWRQWDAAVSPVLVSWMGWLVRAADPRREC G*GTVSRATGAVDS*RDPGH*GVF*PHCRCLVYE HVYKARSCLCQTEFAVAARYSDSVTQGARNSSN E*KCFHAARVFRCKTSSRVSSSKKFLVAFSPVG WTVSSRPGYRRNYVSSSSLP*STKRSWQSLTIFW STNYICRQK*SLPSCRSRWPRF*DAV*EKSGAQ PL*EAAQCQHKALEHHIQSAGH*KSSRLFLQGK GSYLRFWLSV*T*AESG*SCPKTI*QAEDADQGR NPANS*SFASG*FH*GE*TMDRAAGYFCPSGDI S**FQIQESCVSCRGSRKNAFDEHPR*LQEEK* GWVSI*RDPV****I*DPPGHTS*HPTSRVKQQQ RRENTSLFWS*VQ*RTASSTFNEHKDV*EVLAV IYGPPDHGWTSERQLEACPGY*RGTNTCGREVQ RSPTVRASIDLYFRSQISRSRALRQLTRLKNPH* *R*NICTKELLCSPHHPRNENF*HSD*RKDFSP GGAAGKFARLRNEFNPEHCVVGAAYPRGSGGVA APPGGI*SELYAAWC*EQWPVHFCAQGVWYQCSL CEEAL*C*SLPNCSWFAPGGYHADIWC*F*PFD GFT*ELEL*YSNGKPSG*QGPVSCLWTECGPLN *WSYTERPISY*CFT*QNSYQRARVPY*VGISVC EFRVPIDEFRQYSSGDFPTGE*FRYYPQSRDDC GANWFSSKILSQGKR*FKSSTFND*F*KKLQRT RNLPVYI*TKH*GCSGNP*AELTASSDSGHGK*R EIWQKNCNCKYRWHQS*CLNG*HV*HEWFSWLF TAYGFDTR*R*KPVCCQHWEFCRL*KYHQ*YWL L*ICVCQNGRCSPH*SFEFHVC*EI*TGVFSQPE DGFFTL*PLC*VFEGVDVIHG*TGRKFSRYAEK RSHQSHHSTSYQDCRV*RDGIAL*NSKEDSGTL YLRGK*NIWV*PSFVSFGHCKANLEHKH*ITSCF YPSEAGES*VVGGTLGTDIHPEFCGGR**IQK* PSAGGNQGH*TVFFELHPVGR*RSCWV*RKPDV LPTFRVWQCQQSGGSSFHTT*FL*IFA*RSSFSH PEQHHHSV*TGEDPYRERI*IDFFS*PR*PGNF *HHED*RKICQSSSGGVSKACI*AGFTNPGQSR VQ*RSE*VSSQCYLLPLP*FSSASPQYLWRIFC* KEGEWIVQPLQPF*HLSEVIVSEGSQILYSDSS HLLYIRASGSAKWRSDFGGPRSCELKVSGL*GG IQ*RPSPDFIYSDCPAFSADGGLIGEESRF*I*E PDGVSRSP*AI*FSTKRIPFSVLPLSVQCGIS* YASVSPFPHGRSS*CLPVVSKAHLCVPEKAKGS PRQGLSLDPTSFSNSG*AQDTCWKE*I**FLSPH QHILGR*ETSRILFQLQSS*PEH*C*F*LLGCA DHTANLGCDIRLFWNRLHCRQPRNEAAS*GHSA QREVGATCLHGVWTSGSSEHQTGSQGSFTFSSAE *DHQ*ACQSKCVQISSTPGND*GRPGLTGQHWE SVSK*PHMPWRVLQRTVHYQW*RSTHLPDF*IR TA*PSAPERTRHSREPPDGLCAVCAYSAFPGRGG GLHSAFHSAAGCLRAPASCY*GADGERSSPALF TGSPGY*GWCSRSLDPRKFQIK*SDCSKFGEVE SQK*VSVCWFSWHLFPTR*GICAFSFPNGYSQTQ SEENDKHGGAQGNPFPGAVHDASCWNEPRKPEE *VCAQYLHQAARAATHTVCWPRVQ*SRRPCLPA GLRCRGSPGHGHLCCRETSERILEGTRG**WRSD LPFLFCATDRRKPLNRAL*AEIAGGKEFGQRNK SYCARHIYPWQSLLSPLLSGSV*IQADPRLIRE QPGRTHRGIYAAL*FTRSKNSYCPEWRSVHLYVL PH*YGECKSGA*RSKKKRRCWVPSQI*LQEMQT AL*KFFQPNQVH*LGFPFHDGF*HPLCWAEDQP WHDECVQLYLSAR*EQQHHPRVHSD*TTFQIYQG FLLLYSSSQQSPCVSHI*LATVSP*FSPHSQ*Y *ETKSCYSFSPP*L*QRICYSSQNCEEWSSYQA VFPSCVQ*KAPGGQGQCNRYGVCGH*RCVLLRHQ CHYSERHHSAHL*APVC*SPLFRKFVWH*GVFM PTRE*A*YSSFNCGSRTNSNGVGGEFFLSK*FR IDGCIQ**RFPTCPGDSVTSPGYQTLL**CSAVS CHCKIHPRAS*CCSARLSGPGVRLRWHLPSRCI SRWRGNQRRDKTHLRSCLGVTAG*AAGAGIQHG *LSQSSFGVSRPIEKGSKLVV*ECGTSEVSFLGL HQPR*PRGCGSAIDLWRGDQS*ECVHLFHR*LH GL*CSSR*THLFPSEFSSACKN*P*RLCPLHPF WRLL*PCSFRLGAIY*ALAMLCILATAGS*SSPS SSTEARSQGQTSFGYQYHFCAN*PVCKYQGIVD GRLL*R*QGHRVS*IRRLDGLFGGSSMFWTKPP PCLP*N*EYSQSD*PRAPDLC*SRGENPQAPAAI CPLCSEEPHGVHFVVCHPDHHTHQSCTLSQWES RGSSRRERNISR*YSQC**MARSPYR*RDSL*I *SKRKVKTQTHP*PPDSSTASESKWLGASEPSVC GQSRDLFSICSTR*KFIFLYDWQPKQQNKYYTS PGLFLFTPTSAGGLCSDYGRQCTESHHCPVSPH CEEQT*DTNGTKTG*PISSRQASGASCYHARGFV CCAFTPHFLAATGPAQRIGCIFL*GSHSLDQCS EDCRN**Q*TRVPLYGHRKKPIFQVLCGYKERE LSRLYALKHIF*QCKTDFQTAWAYHISPANCGNL QLATL*T*FLC*RNAN*WDAETWQGGSSPYS*Y IPEH*AGGITGEFPPL*RIAHSTWNPKLYGENA TL*RQPSAAEPHHPDCVSSRRILKDLHFCSILAD *QNRVATDLQTGQCQDRCCRPV*GA*AGP*PES SLILLC*QRAAKPLHDENRKGDSSRRHAGLVSG LLPGWW*WCPSFESHPARKPPRADL*HWY*CQER PRSIH*YLHGHLCPPLPVR**IISQACICTEGI CQGTGNSQSRRLHFHPSWFQCGVPLASE*L*SA IVCQTDGRSQLYLVWRL*SQQE*FLPYQHEGYLG KMLLPTSGNYSPRSYV*DLI**HRSVTSSFPN* QLF*GPGCLYSAWRS*TQAPD*SEAHDFIGLCL GRTHLATFYHSDC*RGRVL*DQLQHE*FPG*SAA LL*KFHLHCCYIYILWLAGGNRQACGFQQGHYL CGARFGCLTQDTKSHFKKEGTRKAFSAVEDDRN RNAGP*GLLSSSQSQ*ALSRPLHRGVCHLRYCWS RCSD*QQIRATDAEKA*PQAKHNSDVEFPRRKT DLWVTWVGRPGQRRTFWFV*WS*SCSWS*HFHG AFGASST*TTIY*SKNETWFWNVIHQSHPRWTN* STPDNRFLPPEKQPFI*SG*TSCHRTRAAEIKE SRYRAGIGSACEVRRWNWVVLN**SPRRTGLCK SYRNQCALYTAGNQSHA*TQHTGCTGGQSAHWYH AALHALCDSPEQ*E*GHRDRPSCASQRSEVPQ* ECTDQHLQASDDHSSEIHSAN*GETAPQAAKFL WLRSSRIRGGKI**KPP*KDS*ARWNTNSILL*K SQNQHSSDQAKCVHLQQAPIGS*GPKKHLGVSF DTV*RRCD*SRSIHSGTSL*DQGVHHQ*YPQTF PGGTPQPGSSNPGISGFSWQSYGAFE*CF*RGYW TDKIWKCRGPHQKCYTRSIKLCCQVCWNIIRWL REDDGQSASVRAGVHQVPCSHKW*TPCSRHPWP GSWYHWWTDQCYNFDSGRCENRRGCQRFHIWPWK RACWHCNQASGRRPGFCIRNSPGGERHSHTQRP QDSSTEGSETALLHGAPGAASPIF*EPGGRTGA ALQTHRQHTGRILHRCGEH*QLLRAHLLQSCLLP EKWRLRGSRSHFPRSQIR*PLPLPCLQRPWEGV CAGDQESREHEQWSVHPRPLPPEAHGPCEI*GP CCQVVTRNKLRKEPLL*TAAYVKTQRKPRAAGAG LLKPRC*DGRSRHSADPPGGKRPSSQLTMEAEP ESGLGKLSRNEGK*ILMRKSTNGNRINL*GREL F*IMGNNF*RYWLNNV*KHVLR*I*FLDCPVFC* HVYMYNSVFVNI*ERF*TGSVLCVKVC*L*SNI KLYWIFYCTNSRCLIQDTVYRKAFLKVKECYVL VLETKVFPVKWVEVRAVVLKGTPLTSWLSSWAVS CGTQDWRWPFRRI*ERGLGAHF*FLTPILQRVL RFLQIMM*VIHLAFS*LVLPNLGGNLCSITTWV QVSIVSFLRLLLLERLETLVNSVD*EGKKKSH*T VATNQKST*KCSPAWAATTKNKAPGLFSF**SH RQAS*LHSPRGHRMETPG*EGSRESSRKGDEIG VLKSCVGKFFMEPRFDKGISYPWF*IPAGSKAWY ERPGSCFWCFAFL*GLSR*GEGKRGLTLE*MSH LVIFKFLF**S*SISTTLSHVAESGMTQWISGC VEGFGVYNS*PKSFQDTNEANLLPLPFLSHFPSV SVSVCVCVCVCVRARACMQRGRKGALAQVAT*C SRISFLELRGLVAFAELQVSGLQNGNLAFAALG EF*FVCVLLGGGDDCLSTHALHKMAAGYSTAQDG SSSAASSSASLLAPPQVWLVVFVISNLLPEIMI S*KMRLSEGLIVCVSEPSITFWNKVT*NLLMRL RSLVLLRKSALGRSSAGCSQT*LRKLAAGCPVGW CFRRNPEKCSDAPLGLLSNFNQLFK*LPISCDC TTKHFDICTLGEADVKMESKDHLGRGWVGDGRA NCELLHFSALPCPAALGQTRPEGFRGI*HPLLVL TRKTSKALEETGPAPGSLNAPSLCKLIFSQQCL RLC*DHFYCFSFCFKHTVRL*GK*NKWNKSKLG KEISKATQSLDPAQLADPCHSLAVAASLCSLKGE PGQCFPSPWAWSLHSGKQTSGPFPKSQECLAAW WVLIAMF*RLQGHFVCKYDLGLKIP**LLDKIL KISGSLLCKHYYSHQCVKTLESGSHIRVIIFLPV E*NALWTSQ