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Sequences

Sequence NM_001002799

GTATTTTAGGCGCCATTTTCGAGTGAAGGACCCGGAGCCGAAACACCGGTAGGAGCGGGGAGGTGGGTACTACACAACCGTCTCCAGCCTTGGTCTGAGT GGACTGTCCTGCAGCGACCATGCCCCGTAAAGGCACCCAGCCCTCCACTGCCCGGCGCAGAGAGGAAGGGCCGCCGCCGCCGTCCCCTGACGGCGCCAGC AGCGACGCGGAGCCTGAGCCGCCGTCCGGCCGCACGGAGAGCCCAGCCACCGCCGCAGCAATGACCAATGAAGCTGGAGCTCCTCGGCTTATGATAACTC ATATTGTAAACCAGAACTTCAAATCCTATGCTGGGGAGAAAATTCTGGGACCTTTCCATAAGCGCTTTTCCTGTATTATCGGGCCAAATGGCAGTGGCAA ATCCAATGTTATTGATTCTATGCTTTTTGTGTTTGGCTATCGAGCACAAAAAATAAGATCTAAAAAACTCTCAGTATTAATACATAATTCTGATGAACAC AAGGACATTCAGAGTTGTACAGTAGAAGTTCATTTTCAAAAGATAATTGATAAGGAAGGGGATGATTATGAAGTCATTCCTAACAGTAATTTCTATGTAT CCAGAACGGCCTGCAGAGATAATACTTCTGTCTATCACATAAGTGGAAAGAAAAAGACATTTAAGGATGTTGGAAATCTTCTTCGAAGCCATGGAATTGA CTTGGACCATAATAGATTTTTAATTTTACAGGGTGAAGTTGAACAAATTGCTATGATGAAACCAAAAGGCCAGACTGAACACGATGAGGGTATGCTTGAA TATTTAGAAGATATAATTGGTTGTGGACGGCTAAATGAACCTATTAAAGTCTTGTGTCGGAGAGTTGAAATATTAAATGAACACAGAGGAGAGAAGTTAA ACAGGGTAAAGATGGTGGAAAAGGAAAAGGATGCCTTAGAAGGAGAGAAAAACATAGCTATCGAATTTCTTACCTTGGAAAATGAAATATTTAGAAAAAA GAATCATGTTTGTCAATATTATATTTATGAGTTGCAGAAACGAATTGCTGAAATGGAAACTCAAAAGGAAAAAATTCATGAAGATACCAAAGAAATTAAT GAGAAGAGCAATATACTATCAAATGAAATGAAAGCTAAGAATAAAGATGTAAAAGATACAGAAAAGAAACTGAATAAAATTACAAAATTTATTGAGGAGA ATAAAGAAAAATTTACACAGCTAGATTTGGAAGATGTTCAAGTTAGAGAAAAGTTAAAACATGCCACGAGTAAAGCCAAAAAACTGGAGAAACAACTTCA AAAAGATAAAGAAAAGGTTGAAGAATTTAAAAGTATACCTGCCAAGAGTAACAATATCATTAATGAAACAACAACCAGAAACAATGCCCTCGAGAAGGAA AAAGAGAAAGAAGAAAAAAAATTAAAGGAAGTTATGGATAGCCTTAAACAGGAAACACAAGGGCTTCAGAAAGAAAAAGAAAGTCGAGAGAAAGAACTTA TGGGTTTCAGCAAATCGGTAAATGAAGCACGTTCAAAGATGGATGTAGCCCAGTCAGAACTTGATATCTATCTCAGTCGTCATAATACTGCAGTGTCTCA ATTAACTAAGGCTAAGGAAGCTCTAATTGCAGCTTCTGAGACTCTCAAAGAAAGGAAAGCTGCAATCAGAGATATAGAAGGAAAACTCCCTCAAACTGAA CAAGAATTAAAGGAGAAAGAAAAAGAACTTCAAAAACTTACACAAGAAGAAACAAACTTTAAAAGTTTGGTTCATGATCTCTTTCAAAAAGTTGAAGAAG CAAAGAGCTCATTAGCAATGAATCGAAGTAGGGGGAAAGTCCTTGATGCAATAATTCAAGAAAAAAAATCTGGCAGGATTCCAGGAATATATGGAAGATT GGGGGACTTAGGAGCCATTGATGAAAAATACGACGTGGCTATATCATCCTGTTGTCATGCACTGGACTACATTGTTGTTGATTCTATTGATATAGCCCAA GAATGTGTAAACTTCCTTAAAAGACAAAATATTGGAGTTGCAACCTTTATAGGTTTAGATAAGATGGCTGTATGGGCGAAAAAGATGACCGAAATTCAAA CTCCTGAAAATACTCCTCGTTTATTTGATTTAGTAAAAGTAAAAGATGAGAAAATTCGCCAAGCTTTTTATTTTGCTTTACGAGATACCTTAGTAGCTGA CAACTTGGATCAAGCCACAAGAGTAGCATATCAAAAAGATAGAAGATGGAGAGTGGTAACTTTACAGGGACAAATCATAGAACAGTCAGGTACAATGACT GGTGGTGGAAGCAAAGTAATGAAAGGAAGAATGGGTTCCTCACTTGTTATTGAAATCTCTGAAGAAGAGGTAAACAAAATGGAATCACAGTTGCAAAACG ACTCTAAAAAAGCAATGCAAATCCAAGAACAGAAAGTACAACTTGAAGAAAGAGTAGTTAAGTTACGGCATAGTGAACGAGAAATGAGGAACACACTAGA AAAATTTACTGCAAGCATCCAGCGTTTAATAGAGCAAGAAGAATATTTGAATGTCCAAGTTAAGGAACTTGAAGCTAATGTACTTGCTACAGCCCCTGAC AAAAAAAAGCAGAAATTGCTAGAAGAAAACGTTAGTGCTTTCAAAACAGAATATGATGCTGTGGCTGAGAAAGCTGGTAAAGTAGAAGCTGAGGTTAAAC GCTTACACAATACCATCGTAGAAATCAATAATCATAAACTCAAGGCCCAACAAGACAAACTTGATAAAATAAATAAGCAATTAGATGAATGTGCTTCTGC TATTACTAAAGCCCAAGTAGCAATCAAGACTGCTGACAGAAACCTTCAAAAGGCACAAGACTCTGTCTTGCGTACAGAGAAAGAAATAAAAGATACTGAG AAAGAGGTGGATGACCTAACAGCAGAGCTGAAAAGTCTTGAGGACAAAGCAGCAGAGGTCGTAAAGAATACAAATGCTGCAGAGGAATCCTTACCAGAGA TCCAGAAAGAACATCGCAATCTGCTTCAAGAATTAAAAGTTATTCAAGAAAATGAACATGCTCTTCAAAAAGATGCACTTAGTATTAAGTTGAAACTTGA ACAAATAGATGGTCACATTGCTGAACATAATTCTAAAATAAAATATTGGCACAAAGAGATTTCAAAAATATCACTGCATCCTATAGAAGATAATCCTATT GAAGAGATTTCGGTTCTAAGCCCAGAGGATCTTGAAGCGATCAAGAATCCAGATTCTATAACAAATCAAATTGCACTTTTGGAAGCCCGGTGTCATGAAA TGAAACCAAACCTCGGTGCCATCGCAGAGTATAAAAAGAAGGAAGAATTGTATTTGCAACGGGTAGCAGAATTGGACAAAATTACTTATGAAAGAGACAG TTTTAGACAGGCATATGAAGATCTTCGGAAACAAAGGCTTAATGAATTTATGGCAGGTTTTTATATAATAACAAATAAATTAAAGGAAAATTACCAAATG CTTACTTTGGGAGGGGACGCCGAACTCGAGCTTGTAGACAGCTTGGATCCTTTCTCTGAAGGAATCATGTTCAGTGTTCGACCACCTAAGAAAAGTTGGA AAAAGATCTTCAACCTTTCGGGAGGAGAGAAAACACTTAGTTCATTGGCTTTAGTATTTGCTCTTCACCACTACAAGCCCACTCCCCTTTACTTCATGGA TGAGATTGATGCAGCCCTTGATTTTAAAAATGTGTCCATTGTTGCATTTTATATATATGAACAAACAAAAAATGCACAGTTCATAATAATTTCTCTTCGA AATAATATGTTTGAGATTTCGGATAGACTTATTGGAATTTACAAGACATACAACATAACAAAAAGTGTTGCTGTAAATCCAAAAGAAATTGCATCTAAGG GACTTTGTTGAACTTTATGCTGAAGATTCTTCAAGTTGATTCAGTGTATTACTGATTTTTTTCTATTTGTAAAGGATTATGAGTTGTATAAAATACATAC TCCCTAAACTAGATCATGAAACTGGTTTCTGTTTTATGCAGTTGTCATTTGTAAAGTCTAATAAAATATTCTCTATAATTGCTTCTAGATTACAAAAATA TGACAATCTTGTAAGTAGCAGACTATGGAGAAAAATGAGTTACCTGGAGGGTCAGGTAACTTGCCAAACTAAAAAGTATGTTAGTTGAGGCAAAGTCCTA AGCAAGGTTGTGCTATCAAGGCTCAGCATACCTTCGTGGGCCTTTGATTTACCAACACTGGAAATGCCTGCCAACTAATCTTGGATAGATTCTTTAAGGC ATTCCACTTAGCTTGCCAGTTGAGACAATCACCACAGTTATTACCCAAATACTATGAACATATTTTTGTAAACCAGTCATTCTGAATTATAGTGATGAGA ATTTAAATATATGCTTTTCTAGAATTTGATGTTTGACCATTTATGACTTAATTACCAGAGAGCCAGTAAATTAGGACAGTGTTTCAACAAGCCTAGGCTA TCTCGTAAGTTGAAAAATATCCCACTATAGTTGCTTCATGAGTATGAAGTAAGATGGCCTCTGATTTACACTGGTTCAATTTACAAATTTTCAACTTTAT GATAGGTTTATCCGGGTACTAAATGCATTTCAACTTGATAGTTTCAACTTATGATAGGTTTACCAGGATGTAGTCCCACTGTTGAGGAGCATCTATTTAG GGGTTAATTACTTTAGTAATAAGTGGAAAGTAAGATACCTTGAGTAATGTTTGCCTATAAAATTGTCAGCGTATTTTTACACTATTGGCTCAAGAATGTT ATAATGCTAAGGGACATAAGTTGGCAACCACTTGGTTTTTGGAAGGACTTTCGGTATTGTATTAGAAGTCTGCCCTAGCTGTTAAATTTCTGGGTATTTA TCCTAAGGAATTAATTAAAGAGTTAATTGTTCCTTTCTTCAGTGGGCCATTGTTTTAGATATTTAAAAAATCCAACAGTTTCTATCATAATGTAACTGTA AAAATGTAAACACATTATTAGCATGGACTTTTAAATAAAGATTTAAAGAAAGCAA

refseq_SMC4.F2 (forward primer)
refseq_SMC4.R2 (reverse primer)
Alternative acceptor

Frame 0

VF*APFSSEGPGAETPVGAGRWVLHNRLQPWSE WTVLQRPCPVKAPSPPLPGAERKGRRRRPLTAPA ATRSLSRRPAARRAQPPPQQ*PMKLELLGL**L IL*TRTSNPMLGRKFWDLSISAFPVLSGQMAVA NPMLLILCFLCLAIEHKK*DLKNSQY*YIILMNT RTFRVVQ*KFIFKR*LIRKGMIMKSFLTVISMY PERPAEIILLSIT*VERKRHLRMLEIFFEAMEL TWTIIDF*FYRVKLNKLL**NQKARLNTMRVCLN I*KI*LVVDG*MNLLKSCVGELKY*MNTEERS* TG*RWWKRKRMP*KERKT*LSNFLPWKMKYLEK RIMFVNIIFMSCRNELLKWKLKRKKFMKIPKKLM RRAIYYQMK*KLRIKM*KIQKRN*IKLQNLLRR IKKNLHS*IWKMFKLEKS*NMPRVKPKNWRNNF KKIKKRLKNLKVYLPRVTISLMKQQPETMPSRRK KRKKKKN*RKLWIALNRKHKGFRKKKKVERKNL WVSANR*MKHVQRWM*PSQNLISISVVIILQCL N*LRLRKL*LQLLRLSKKGKLQSEI*KENSLKLN KN*RRKKKNFKNLHKKKQTLKVWFMISFKKLKK QRAH*Q*IEVGGKSLMQ*FKKKNLAGFQEYMED WGT*EPLMKNTTWLYHPVVMHWTTLLLILLI*PK NV*TSLKDKILELQPL*V*IRWLYGRKR*PKFK LLKILLVYLI**K*KMRKFAKLFILLYEIP**L TTWIKPQE*HIKKIEDGEW*LYRDKS*NSQVQ*L VVEAK**KEEWVPHLLLKSLKKR*TKWNHSCKT TLKKQCKSKNRKYNLKKE*LSYGIVNEK*GTH* KNLLQASSV**SKKNI*MSKLRNLKLMYLLQPLT KKSRNC*KKTLVLSKQNMMLWLRKLVK*KLRLN AYTIPS*KSIIINSRPNKTNLIK*ISN*MNVLL LLLKPK*QSRLLTETFKRHKTLSCVQRKK*KILR KRWMT*QQS*KVLRTKQQRS*RIQMLQRNPYQR SRKNIAICFKN*KLFKKMNMLFKKMHLVLS*NL NK*MVTLLNIILK*NIGTKRFQKYHCIL*KIILL KRFRF*AQRILKRSRIQIL*QIKLHFWKPGVMK *NQTSVPSQSIKRRKNCICNG*QNWTKLLMKET VLDRHMKIFGNKGLMNLWQVFI**QIN*RKITKC LLWEGTPNSSL*TAWILSLKESCSVFDHLRKVG KRSSTFREERKHLVHWL*YLLFTTTSPLPFTSW MRLMQPLILKMCPLLHFIYMNKQKMHSS**FLFE IICLRFRIDLLEFTRHTT*QKVLL*IQKKLHLR DFVELYAEDSSS*FSVLLIFFYL*RIMSCIKYI LPKLDHETGFCFMQLSFVKSNKIFSIIASRLQKY DNLVSSRLWRKMSYLEGQVTCQTKKYVS*GKVL SKVVLSRLSIPSWAFDLPTLEMPAN*SWIDSLR HST*LAS*DNHHSYYPNTMNIFL*TSHSEL***E FKYMLF*NLMFDHL*LNYQRASKLGQCFNKPRL SRKLKNIPL*LLHEYEVRWPLIYTGSIYKFSTL **VYPGTKCIST**FQLMIGLPGCSPTVEEHLFR G*LL***VESKIP*VMFAYKIVSVFLHYWLKNV IMLRDISWQPLGFWKDFRYCIRSLP*LLNFWVF ILRN*LKS*LFLSSVGHCFRYLKNPTVSIIM*L* KCKHIISMDF*IKI*RKQ

Frame 1

YFRRHFRVKDPEPKHR*ERGGGYYTTVSSLGLS GLSCSDHAP*RHPALHCPAQRGRAAAAVP*RRQ QRRGA*AAVRPHGEPSHRRSNDQ*SWSSSAYDNS YCKPELQILCWGENSGTFP*ALFLYYRAKWQWQ IQCY*FYAFCVWLSSTKNKI*KTLSINT*F**T QGHSELYSRSSFSKDN**GRG*L*SHS*Q*FLCI QNGLQR*YFCLSHKWKEKDI*GCWKSSSKPWN* LGP**IFNFTG*S*TNCYDETKRPD*TR*GYA* IFRRYNWLWTAK*TY*SLVSES*NIK*TQRREVK QGKDGGKGKGCLRRREKHSYRISYLGK*NI*KK ESCLSILYL*VAETNC*NGNSKGKNS*RYQRN* *EEQYTIK*NES*E*RCKRYRKETE*NYKIY*GE *RKIYTARFGRCSS*RKVKTCHE*SQKTGETTS KR*RKG*RI*KYTCQE*QYH**NNNQKQCPREG KRERRKKIKGSYG*P*TGNTRASERKRKSRERTY GFQQIGK*STFKDGCSPVRT*YLSQSS*YCSVS IN*G*GSSNCSF*DSQRKESCNQRYRRKTPSN* TRIKGERKRTSKTYTRRNKL*KFGS*SLSKS*RS KELISNESK*GESP*CNNSRKKIWQDSRNIWKI GGLRSH**KIRRGYIILLSCTGLHCC*FY*YSP RMCKLP*KTKYWSCNLYRFR*DGCMGEKDDRNSN S*KYSSFI*FSKSKR*ENSPSFLFCFTRYLSS* QLGSSHKSSISKR*KMESGNFTGTNHRTVRYND WWWKQSNERKNGFLTCY*NL*RRGKQNGITVAKR L*KSNANPRTESTT*RKSS*VTA**TRNEEHTR KIYCKHPAFNRARRIFECPS*GT*S*CTCYSP* QKKAEIARRKR*CFQNRI*CCG*ESW*SRS*G*T LTQYHRRNQ*S*TQGPTRQT**NK*AIR*MCFC YY*SPSSNQDC*QKPSKGTRLCLAYRERNKRY* ERGG*PNSRAEKS*GQSSRGRKEYKCCRGILTRD PERTSQSASRIKSYSRK*TCSSKRCT*Y*VET* TNRWSHC*T*F*NKILAQRDFKNITASYRR*SY *RDFGSKPRGS*SDQESRFYNKSNCTFGSPVS*N ETKPRCHRRV*KEGRIVFATGSRIGQNYL*KRQ F*TGI*RSSETKA**IYGRFLYNNK*IKGKLPN AYFGRGRRTRACRQLGSFL*RNHVQCSTT*EKLE KDLQPFGRRENT*FIGFSICSSPLQAHSPLLHG *D*CSP*F*KCVHCCILYI*TNKKCTVHNNFSS K*YV*DFG*TYWNLQDIQHNKKCCCKSKRNCI*G TLLNFMLKILQVDSVYY*FFSICKGL*VV*NTY SLN*IMKLVSVLCSCHL*SLIKYSL*LLLDYKN MTIL*VADYGEK*VTWRVR*LAKLKSMLVEAKS* ARLCYQGSAYLRGPLIYQHWKCLPTNLG*IL*G IPLSLPVETITTVITQIL*TYFCKPVILNYSDE NLNICFSRI*CLTIYDLITREPVN*DSVSTSLGY LVS*KISHYSCFMSMK*DGL*FTLVQFTNFQLY DRFIRVLNAFQLDSFNL**VYQDVVPLLRSIYL GVNYFSNKWKVRYLE*CLPIKLSAYFYTIGSRML *C*GT*VGNHLVFGRTFGIVLEVCPSC*ISGYL S*GIN*RVNCSFLQWAIVLDI*KIQQFLS*CNC KNVNTLLAWTFK*RFKES

Frame 2

ILGAIFE*RTRSRNTGRSGEVGTTQPSPALV*V DCPAATMPRKGTQPSTARRREEGPPPPSPDGAS SDAEPEPPSGRTESPATAAAMTNEAGAPRLMIT HIVNQNFKSYAGEKILGPFHKRFSCIIGPNGSGK SNVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEH KDIQSCTVEVHFQKIIDKEGDDYEVIPNSNFYV SRTACRDNTSVYHISGKKKTFKDVGNLLRSHGID LDHNRFLILQGEVEQIAMMKPKGQTEHDEGMLE YLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKL NRVKMVEKEKDALEGEKNIAIEFLTLENEIFRKK NHVCQYYIYELQKRIAEMETQKEKIHEDTKEIN EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEE NKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQ KDKEKVEEFKSIPAKSNNIINETTTRNNALEKE KEKEEKKLKEVMDSLKQETQGLQKEKESREKEL MGFSKSVNEARSKMDVAQSELDIYLSRHNTAVSQ LTKAKEALIAASETLKERKAAIRDIEGKLPQTE QELKEKEKELQKLTQEETNFKSLVHDLFQKVEE AKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRL GDLGAIDEKYDVAISSCCHALDYIVVDSIDIAQ ECVNFLKRQNIGVATFIGLDKMAVWAKKMTEIQ TPENTPRLFDLVKVKDEKIRQAFYFALRDTLVAD NLDQATRVAYQKDRRWRVVTLQGQIIEQSGTMT GGGSKVMKGRMGSSLVIEISEEEVNKMESQLQN DSKKAMQIQEQKVQLEERVVKLRHSEREMRNTLE KFTASIQRLIEQEEYLNVQVKELEANVLATAPD KKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVK RLHNTIVEINNHKLKAQQDKLDKINKQLDECASA ITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTE KEVDDLTAELKSLEDKAAEVVKNTNAAEESLPE IQKEHRNLLQELKVIQENEHALQKDALSIKLKLE QIDGHIAEHNSKIKYWHKEISKISLHPIEDNPI EEISVLSPEDLEAIKNPDSITNQIALLEARCHE MKPNLGAIAEYKKKEELYLQRVAELDKITYERDS FRQAYEDLRKQRLNEFMAGFYIITNKLKENYQM LTLGGDAELELVDSLDPFSEGIMFSVRPPKKSW KKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMD EIDAALDFKNVSIVAFYIYEQTKNAQFIIISLR NNMFEISDRLIGIYKTYNITKSVAVNPKEIASK GLC*TLC*RFFKLIQCITDFFLFVKDYELYKIHT P*TRS*NWFLFYAVVICKV**NILYNCF*ITKI *QSCK*QTMEKNELPGGSGNLPN*KVC*LRQSP KQGCAIKAQHTFVGL*FTNTGNACQLILDRFFKA FHLACQLRQSPQLLPKYYEHIFVNQSF*IIVMR I*IYAFLEFDV*PFMT*LPESQ*IRTVFQQA*A IS*VEKYPTIVAS*V*SKMASDLHWFNLQIFNFM IGLSGY*MHFNLIVSTYDRFTRM*SHC*GASI* GLITLVISGK*DTLSNVCL*NCQRIFTLLAQEC YNAKGHKLATTWFLEGLSVLY*KSALAVKFLGIY PKELIKELIVPFFSGPLF*IFKKSNSFYHNVTV KM*THY*HGLLNKDLKKA

Sequence NM_001002800

GTATTTTAGGCGCCATTTTCGAGTGAAGGACCCGGAGCCGAAACACCGGTAGGAGCGGGGAGGTGGGTACTACACAACCGTCTCCAGCCTTGGTCTGAGT GGACTGTCCTGCAGCGACCATGCCCCGTAAAGGCACCCAGCCCTCCACTGCCCGGCGCAGAGAGGAAGGGCCGCCGCCGCCGTCCCCTGACGGCGCCAGC AGCGACGCGGAGCCTGAGCCGCCGTCCGGCCGCACGGAGAGCCCAGCCACCGCCGCAGAGACTGCAAGTGAGGAACTTGATAATAGAAGTTTAGAAGAGA TTTTGAACAGCATTCCTCCTCCCCCGCCTCCAGCAATGACCAATGAAGCTGGAGCTCCTCGGCTTATGATAACTCATATTGTAAACCAGAACTTCAAATC CTATGCTGGGGAGAAAATTCTGGGACCTTTCCATAAGCGCTTTTCCTGTATTATCGGGCCAAATGGCAGTGGCAAATCCAATGTTATTGATTCTATGCTT TTTGTGTTTGGCTATCGAGCACAAAAAATAAGATCTAAAAAACTCTCAGTATTAATACATAATTCTGATGAACACAAGGACATTCAGAGTTGTACAGTAG AAGTTCATTTTCAAAAGATAATTGATAAGGAAGGGGATGATTATGAAGTCATTCCTAACAGTAATTTCTATGTATCCAGAACGGCCTGCAGAGATAATAC TTCTGTCTATCACATAAGTGGAAAGAAAAAGACATTTAAGGATGTTGGAAATCTTCTTCGAAGCCATGGAATTGACTTGGACCATAATAGATTTTTAATT TTACAGGGTGAAGTTGAACAAATTGCTATGATGAAACCAAAAGGCCAGACTGAACACGATGAGGGTATGCTTGAATATTTAGAAGATATAATTGGTTGTG GACGGCTAAATGAACCTATTAAAGTCTTGTGTCGGAGAGTTGAAATATTAAATGAACACAGAGGAGAGAAGTTAAACAGGGTAAAGATGGTGGAAAAGGA AAAGGATGCCTTAGAAGGAGAGAAAAACATAGCTATCGAATTTCTTACCTTGGAAAATGAAATATTTAGAAAAAAGAATCATGTTTGTCAATATTATATT TATGAGTTGCAGAAACGAATTGCTGAAATGGAAACTCAAAAGGAAAAAATTCATGAAGATACCAAAGAAATTAATGAGAAGAGCAATATACTATCAAATG AAATGAAAGCTAAGAATAAAGATGTAAAAGATACAGAAAAGAAACTGAATAAAATTACAAAATTTATTGAGGAGAATAAAGAAAAATTTACACAGCTAGA TTTGGAAGATGTTCAAGTTAGAGAAAAGTTAAAACATGCCACGAGTAAAGCCAAAAAACTGGAGAAACAACTTCAAAAAGATAAAGAAAAGGTTGAAGAA TTTAAAAGTATACCTGCCAAGAGTAACAATATCATTAATGAAACAACAACCAGAAACAATGCCCTCGAGAAGGAAAAAGAGAAAGAAGAAAAAAAATTAA AGGAAGTTATGGATAGCCTTAAACAGGAAACACAAGGGCTTCAGAAAGAAAAAGAAAGTCGAGAGAAAGAACTTATGGGTTTCAGCAAATCGGTAAATGA AGCACGTTCAAAGATGGATGTAGCCCAGTCAGAACTTGATATCTATCTCAGTCGTCATAATACTGCAGTGTCTCAATTAACTAAGGCTAAGGAAGCTCTA ATTGCAGCTTCTGAGACTCTCAAAGAAAGGAAAGCTGCAATCAGAGATATAGAAGGAAAACTCCCTCAAACTGAACAAGAATTAAAGGAGAAAGAAAAAG AACTTCAAAAACTTACACAAGAAGAAACAAACTTTAAAAGTTTGGTTCATGATCTCTTTCAAAAAGTTGAAGAAGCAAAGAGCTCATTAGCAATGAATCG AAGTAGGGGGAAAGTCCTTGATGCAATAATTCAAGAAAAAAAATCTGGCAGGATTCCAGGAATATATGGAAGATTGGGGGACTTAGGAGCCATTGATGAA AAATACGACGTGGCTATATCATCCTGTTGTCATGCACTGGACTACATTGTTGTTGATTCTATTGATATAGCCCAAGAATGTGTAAACTTCCTTAAAAGAC AAAATATTGGAGTTGCAACCTTTATAGGTTTAGATAAGATGGCTGTATGGGCGAAAAAGATGACCGAAATTCAAACTCCTGAAAATACTCCTCGTTTATT TGATTTAGTAAAAGTAAAAGATGAGAAAATTCGCCAAGCTTTTTATTTTGCTTTACGAGATACCTTAGTAGCTGACAACTTGGATCAAGCCACAAGAGTA GCATATCAAAAAGATAGAAGATGGAGAGTGGTAACTTTACAGGGACAAATCATAGAACAGTCAGGTACAATGACTGGTGGTGGAAGCAAAGTAATGAAAG GAAGAATGGGTTCCTCACTTGTTATTGAAATCTCTGAAGAAGAGGTAAACAAAATGGAATCACAGTTGCAAAACGACTCTAAAAAAGCAATGCAAATCCA AGAACAGAAAGTACAACTTGAAGAAAGAGTAGTTAAGTTACGGCATAGTGAACGAGAAATGAGGAACACACTAGAAAAATTTACTGCAAGCATCCAGCGT TTAATAGAGCAAGAAGAATATTTGAATGTCCAAGTTAAGGAACTTGAAGCTAATGTACTTGCTACAGCCCCTGACAAAAAAAAGCAGAAATTGCTAGAAG AAAACGTTAGTGCTTTCAAAACAGAATATGATGCTGTGGCTGAGAAAGCTGGTAAAGTAGAAGCTGAGGTTAAACGCTTACACAATACCATCGTAGAAAT CAATAATCATAAACTCAAGGCCCAACAAGACAAACTTGATAAAATAAATAAGCAATTAGATGAATGTGCTTCTGCTATTACTAAAGCCCAAGTAGCAATC AAGACTGCTGACAGAAACCTTCAAAAGGCACAAGACTCTGTCTTGCGTACAGAGAAAGAAATAAAAGATACTGAGAAAGAGGTGGATGACCTAACAGCAG AGCTGAAAAGTCTTGAGGACAAAGCAGCAGAGGTCGTAAAGAATACAAATGCTGCAGAGGAATCCTTACCAGAGATCCAGAAAGAACATCGCAATCTGCT TCAAGAATTAAAAGTTATTCAAGAAAATGAACATGCTCTTCAAAAAGATGCACTTAGTATTAAGTTGAAACTTGAACAAATAGATGGTCACATTGCTGAA CATAATTCTAAAATAAAATATTGGCACAAAGAGATTTCAAAAATATCACTGCATCCTATAGAAGATAATCCTATTGAAGAGATTTCGGTTCTAAGCCCAG AGGATCTTGAAGCGATCAAGAATCCAGATTCTATAACAAATCAAATTGCACTTTTGGAAGCCCGGTGTCATGAAATGAAACCAAACCTCGGTGCCATCGC AGAGTATAAAAAGAAGGAAGAATTGTATTTGCAACGGGTAGCAGAATTGGACAAAATTACTTATGAAAGAGACAGTTTTAGACAGGCATATGAAGATCTT CGGAAACAAAGGCTTAATGAATTTATGGCAGGTTTTTATATAATAACAAATAAATTAAAGGAAAATTACCAAATGCTTACTTTGGGAGGGGACGCCGAAC TCGAGCTTGTAGACAGCTTGGATCCTTTCTCTGAAGGAATCATGTTCAGTGTTCGACCACCTAAGAAAAGTTGGAAAAAGATCTTCAACCTTTCGGGAGG AGAGAAAACACTTAGTTCATTGGCTTTAGTATTTGCTCTTCACCACTACAAGCCCACTCCCCTTTACTTCATGGATGAGATTGATGCAGCCCTTGATTTT AAAAATGTGTCCATTGTTGCATTTTATATATATGAACAAACAAAAAATGCACAGTTCATAATAATTTCTCTTCGAAATAATATGTTTGAGATTTCGGATA GACTTATTGGAATTTACAAGACATACAACATAACAAAAAGTGTTGCTGTAAATCCAAAAGAAATTGCATCTAAGGGACTTTGTTGAACTTTATGCTGAAG ATTCTTCAAGTTGATTCAGTGTATTACTGATTTTTTTCTATTTGTAAAGGATTATGAGTTGTATAAAATACATACTCCCTAAACTAGATCATGAAACTGG TTTCTGTTTTATGCAGTTGTCATTTGTAAAGTCTAATAAAATATTCTCTATAATTGCTTCTAGATTACAAAAATATGACAATCTTGTAAGTAGCAGACTA TGGAGAAAAATGAGTTACCTGGAGGGTCAGGTAACTTGCCAAACTAAAAAGTATGTTAGTTGAGGCAAAGTCCTAAGCAAGGTTGTGCTATCAAGGCTCA GCATACCTTCGTGGGCCTTTGATTTACCAACACTGGAAATGCCTGCCAACTAATCTTGGATAGATTCTTTAAGGCATTCCACTTAGCTTGCCAGTTGAGA CAATCACCACAGTTATTACCCAAATACTATGAACATATTTTTGTAAACCAGTCATTCTGAATTATAGTGATGAGAATTTAAATATATGCTTTTCTAGAAT TTGATGTTTGACCATTTATGACTTAATTACCAGAGAGCCAGTAAATTAGGACAGTGTTTCAACAAGCCTAGGCTATCTCGTAAGTTGAAAAATATCCCAC TATAGTTGCTTCATGAGTATGAAGTAAGATGGCCTCTGATTTACACTGGTTCAATTTACAAATTTTCAACTTTATGATAGGTTTATCCGGGTACTAAATG CATTTCAACTTGATAGTTTCAACTTATGATAGGTTTACCAGGATGTAGTCCCACTGTTGAGGAGCATCTATTTAGGGGTTAATTACTTTAGTAATAAGTG GAAAGTAAGATACCTTGAGTAATGTTTGCCTATAAAATTGTCAGCGTATTTTTACACTATTGGCTCAAGAATGTTATAATGCTAAGGGACATAAGTTGGC AACCACTTGGTTTTTGGAAGGACTTTCGGTATTGTATTAGAAGTCTGCCCTAGCTGTTAAATTTCTGGGTATTTATCCTAAGGAATTAATTAAAGAGTTA ATTGTTCCTTTCTTCAGTGGGCCATTGTTTTAGATATTTAAAAAATCCAACAGTTTCTATCATAATGTAACTGTAAAAATGTAAACACATTATTAGCATG GACTTTTAAATAAAGATTTAAAGAAAGCAA

refseq_SMC4.F2 (forward primer)
refseq_SMC4.R2 (reverse primer)
Alternative acceptor

Frame 0

VF*APFSSEGPGAETPVGAGRWVLHNRLQPWSE WTVLQRPCPVKAPSPPLPGAERKGRRRRPLTAPA ATRSLSRRPAARRAQPPPQRLQVRNLIIEV*KR F*TAFLLPRLQQ*PMKLELLGL**LIL*TRTSN PMLGRKFWDLSISAFPVLSGQMAVANPMLLILCF LCLAIEHKK*DLKNSQY*YIILMNTRTFRVVQ* KFIFKR*LIRKGMIMKSFLTVISMYPERPAEII LLSIT*VERKRHLRMLEIFFEAMELTWTIIDF*F YRVKLNKLL**NQKARLNTMRVCLNI*KI*LVV DG*MNLLKSCVGELKY*MNTEERS*TG*RWWKR KRMP*KERKT*LSNFLPWKMKYLEKRIMFVNIIF MSCRNELLKWKLKRKKFMKIPKKLMRRAIYYQM K*KLRIKM*KIQKRN*IKLQNLLRRIKKNLHS* IWKMFKLEKS*NMPRVKPKNWRNNFKKIKKRLKN LKVYLPRVTISLMKQQPETMPSRRKKRKKKKN* RKLWIALNRKHKGFRKKKKVERKNLWVSANR*M KHVQRWM*PSQNLISISVVIILQCLN*LRLRKL* LQLLRLSKKGKLQSEI*KENSLKLNKN*RRKKK NFKNLHKKKQTLKVWFMISFKKLKKQRAH*Q*I EVGGKSLMQ*FKKKNLAGFQEYMEDWGT*EPLMK NTTWLYHPVVMHWTTLLLILLI*PKNV*TSLKD KILELQPL*V*IRWLYGRKR*PKFKLLKILLVY LI**K*KMRKFAKLFILLYEIP**LTTWIKPQE* HIKKIEDGEW*LYRDKS*NSQVQ*LVVEAK**K EEWVPHLLLKSLKKR*TKWNHSCKTTLKKQCKS KNRKYNLKKE*LSYGIVNEK*GTH*KNLLQASSV **SKKNI*MSKLRNLKLMYLLQPLTKKSRNC*K KTLVLSKQNMMLWLRKLVK*KLRLNAYTIPS*K SIIINSRPNKTNLIK*ISN*MNVLLLLLKPK*QS RLLTETFKRHKTLSCVQRKK*KILRKRWMT*QQ S*KVLRTKQQRS*RIQMLQRNPYQRSRKNIAIC FKN*KLFKKMNMLFKKMHLVLS*NLNK*MVTLLN IILK*NIGTKRFQKYHCIL*KIILLKRFRF*AQ RILKRSRIQIL*QIKLHFWKPGVMK*NQTSVPS QSIKRRKNCICNG*QNWTKLLMKETVLDRHMKIF GNKGLMNLWQVFI**QIN*RKITKCLLWEGTPN SSL*TAWILSLKESCSVFDHLRKVGKRSSTFRE ERKHLVHWL*YLLFTTTSPLPFTSWMRLMQPLIL KMCPLLHFIYMNKQKMHSS**FLFEIICLRFRI DLLEFTRHTT*QKVLL*IQKKLHLRDFVELYAE DSSS*FSVLLIFFYL*RIMSCIKYILPKLDHETG FCFMQLSFVKSNKIFSIIASRLQKYDNLVSSRL WRKMSYLEGQVTCQTKKYVS*GKVLSKVVLSRL SIPSWAFDLPTLEMPAN*SWIDSLRHST*LAS*D NHHSYYPNTMNIFL*TSHSEL***EFKYMLF*N LMFDHL*LNYQRASKLGQCFNKPRLSRKLKNIP L*LLHEYEVRWPLIYTGSIYKFSTL**VYPGTKC IST**FQLMIGLPGCSPTVEEHLFRG*LL***V ESKIP*VMFAYKIVSVFLHYWLKNVIMLRDISW QPLGFWKDFRYCIRSLP*LLNFWVFILRN*LKS* LFLSSVGHCFRYLKNPTVSIIM*L*KCKHIISM DF*IKI*RKQ

Frame 1

YFRRHFRVKDPEPKHR*ERGGGYYTTVSSLGLS GLSCSDHAP*RHPALHCPAQRGRAAAAVP*RRQ QRRGA*AAVRPHGEPSHRRRDCK*GT***KFRRD FEQHSSSPASSNDQ*SWSSSAYDNSYCKPELQI LCWGENSGTFP*ALFLYYRAKWQWQIQCY*FYA FCVWLSSTKNKI*KTLSINT*F**TQGHSELYSR SSFSKDN**GRG*L*SHS*Q*FLCIQNGLQR*Y FCLSHKWKEKDI*GCWKSSSKPWN*LGP**IFN FTG*S*TNCYDETKRPD*TR*GYA*IFRRYNWLW TAK*TY*SLVSES*NIK*TQRREVKQGKDGGKG KGCLRRREKHSYRISYLGK*NI*KKESCLSILY L*VAETNC*NGNSKGKNS*RYQRN**EEQYTIK* NES*E*RCKRYRKETE*NYKIY*GE*RKIYTAR FGRCSS*RKVKTCHE*SQKTGETTSKR*RKG*R I*KYTCQE*QYH**NNNQKQCPREGKRERRKKIK GSYG*P*TGNTRASERKRKSRERTYGFQQIGK* STFKDGCSPVRT*YLSQSS*YCSVSIN*G*GSS NCSF*DSQRKESCNQRYRRKTPSN*TRIKGERKR TSKTYTRRNKL*KFGS*SLSKS*RSKELISNES K*GESP*CNNSRKKIWQDSRNIWKIGGLRSH** KIRRGYIILLSCTGLHCC*FY*YSPRMCKLP*KT KYWSCNLYRFR*DGCMGEKDDRNSNS*KYSSFI *FSKSKR*ENSPSFLFCFTRYLSS*QLGSSHKS SISKR*KMESGNFTGTNHRTVRYNDWWWKQSNER KNGFLTCY*NL*RRGKQNGITVAKRL*KSNANP RTESTT*RKSS*VTA**TRNEEHTRKIYCKHPA FNRARRIFECPS*GT*S*CTCYSP*QKKAEIARR KR*CFQNRI*CCG*ESW*SRS*G*TLTQYHRRN Q*S*TQGPTRQT**NK*AIR*MCFCYY*SPSSN QDC*QKPSKGTRLCLAYRERNKRY*ERGG*PNSR AEKS*GQSSRGRKEYKCCRGILTRDPERTSQSA SRIKSYSRK*TCSSKRCT*Y*VET*TNRWSHC* T*F*NKILAQRDFKNITASYRR*SY*RDFGSKPR GS*SDQESRFYNKSNCTFGSPVS*NETKPRCHR RV*KEGRIVFATGSRIGQNYL*KRQF*TGI*RS SETKA**IYGRFLYNNK*IKGKLPNAYFGRGRRT RACRQLGSFL*RNHVQCSTT*EKLEKDLQPFGR RENT*FIGFSICSSPLQAHSPLLHG*D*CSP*F *KCVHCCILYI*TNKKCTVHNNFSSK*YV*DFG* TYWNLQDIQHNKKCCCKSKRNCI*GTLLNFMLK ILQVDSVYY*FFSICKGL*VV*NTYSLN*IMKL VSVLCSCHL*SLIKYSL*LLLDYKNMTIL*VADY GEK*VTWRVR*LAKLKSMLVEAKS*ARLCYQGS AYLRGPLIYQHWKCLPTNLG*IL*GIPLSLPVE TITTVITQIL*TYFCKPVILNYSDENLNICFSRI *CLTIYDLITREPVN*DSVSTSLGYLVS*KISH YSCFMSMK*DGL*FTLVQFTNFQLYDRFIRVLN AFQLDSFNL**VYQDVVPLLRSIYLGVNYFSNKW KVRYLE*CLPIKLSAYFYTIGSRML*C*GT*VG NHLVFGRTFGIVLEVCPSC*ISGYLS*GIN*RV NCSFLQWAIVLDI*KIQQFLS*CNCKNVNTLLAW TFK*RFKES

Frame 2

ILGAIFE*RTRSRNTGRSGEVGTTQPSPALV*V DCPAATMPRKGTQPSTARRREEGPPPPSPDGAS SDAEPEPPSGRTESPATAAETASEELDNRSLEE ILNSIPPPPPPAMTNEAGAPRLMITHIVNQNFKS YAGEKILGPFHKRFSCIIGPNGSGKSNVIDSML FVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTV EVHFQKIIDKEGDDYEVIPNSNFYVSRTACRDNT SVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLI LQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGC GRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKE KDALEGEKNIAIEFLTLENEIFRKKNHVCQYYI YELQKRIAEMETQKEKIHEDTKEINEKSNILSN EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLD LEDVQVREKLKHATSKAKKLEKQLQKDKEKVEE FKSIPAKSNNIINETTTRNNALEKEKEKEEKKL KEVMDSLKQETQGLQKEKESREKELMGFSKSVNE ARSKMDVAQSELDIYLSRHNTAVSQLTKAKEAL IAASETLKERKAAIRDIEGKLPQTEQELKEKEK ELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNR SRGKVLDAIIQEKKSGRIPGIYGRLGDLGAIDE KYDVAISSCCHALDYIVVDSIDIAQECVNFLKR QNIGVATFIGLDKMAVWAKKMTEIQTPENTPRLF DLVKVKDEKIRQAFYFALRDTLVADNLDQATRV AYQKDRRWRVVTLQGQIIEQSGTMTGGGSKVMK GRMGSSLVIEISEEEVNKMESQLQNDSKKAMQIQ EQKVQLEERVVKLRHSEREMRNTLEKFTASIQR LIEQEEYLNVQVKELEANVLATAPDKKKQKLLE ENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEI NNHKLKAQQDKLDKINKQLDECASAITKAQVAI KTADRNLQKAQDSVLRTEKEIKDTEKEVDDLTA ELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLL QELKVIQENEHALQKDALSIKLKLEQIDGHIAE HNSKIKYWHKEISKISLHPIEDNPIEEISVLSP EDLEAIKNPDSITNQIALLEARCHEMKPNLGAIA EYKKKEELYLQRVAELDKITYERDSFRQAYEDL RKQRLNEFMAGFYIITNKLKENYQMLTLGGDAE LELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGG EKTLSSLALVFALHHYKPTPLYFMDEIDAALDF KNVSIVAFYIYEQTKNAQFIIISLRNNMFEISD RLIGIYKTYNITKSVAVNPKEIASKGLC*TLC*R FFKLIQCITDFFLFVKDYELYKIHTP*TRS*NW FLFYAVVICKV**NILYNCF*ITKI*QSCK*QT MEKNELPGGSGNLPN*KVC*LRQSPKQGCAIKAQ HTFVGL*FTNTGNACQLILDRFFKAFHLACQLR QSPQLLPKYYEHIFVNQSF*IIVMRI*IYAFLE FDV*PFMT*LPESQ*IRTVFQQA*AIS*VEKYPT IVAS*V*SKMASDLHWFNLQIFNFMIGLSGY*M HFNLIVSTYDRFTRM*SHC*GASI*GLITLVIS GK*DTLSNVCL*NCQRIFTLLAQECYNAKGHKLA TTWFLEGLSVLY*KSALAVKFLGIYPKELIKEL IVPFFSGPLF*IFKKSNSFYHNVTVKM*THY*H GLLNKDLKKA

Sequence NM_005496

CAACAAACTAAGCAGTTGCTCAATCGTTGATTGATCCTCAGGCACGTCTAGATTTTCCCACTTACATAGGTCTTGTTAAGAAACCAGTCCTGCCTTCTTG CCACTCGTGTCTTTCGATGGCTCCCTTCCCGAAGTCCCGCTGCCTCTAAGCGGAGTGTTAAGCGGGGCTCTCGGAAGCCGGTGGACCGAGATTTCCCCGG GTGGGGCGGGCGCGGTGTAGCGGCCCGCGGGCTGACTTGCTCCCGGCTGTCCCCCGGCCCCAGCGACCATGCCCCGTAAAGGCACCCAGCCCTCCACTGC CCGGCGCAGAGAGGAAGGGCCGCCGCCGCCGTCCCCTGACGGCGCCAGCAGCGACGCGGAGCCTGAGCCGCCGTCCGGCCGCACGGAGAGCCCAGCCACC GCCGCAGAGACTGCAAGTGAGGAACTTGATAATAGAAGTTTAGAAGAGATTTTGAACAGCATTCCTCCTCCCCCGCCTCCAGCAATGACCAATGAAGCTG GAGCTCCTCGGCTTATGATAACTCATATTGTAAACCAGAACTTCAAATCCTATGCTGGGGAGAAAATTCTGGGACCTTTCCATAAGCGCTTTTCCTGTAT TATCGGGCCAAATGGCAGTGGCAAATCCAATGTTATTGATTCTATGCTTTTTGTGTTTGGCTATCGAGCACAAAAAATAAGATCTAAAAAACTCTCAGTA TTAATACATAATTCTGATGAACACAAGGACATTCAGAGTTGTACAGTAGAAGTTCATTTTCAAAAGATAATTGATAAGGAAGGGGATGATTATGAAGTCA TTCCTAACAGTAATTTCTATGTATCCAGAACGGCCTGCAGAGATAATACTTCTGTCTATCACATAAGTGGAAAGAAAAAGACATTTAAGGATGTTGGAAA TCTTCTTCGAAGCCATGGAATTGACTTGGACCATAATAGATTTTTAATTTTACAGGGTGAAGTTGAACAAATTGCTATGATGAAACCAAAAGGCCAGACT GAACACGATGAGGGTATGCTTGAATATTTAGAAGATATAATTGGTTGTGGACGGCTAAATGAACCTATTAAAGTCTTGTGTCGGAGAGTTGAAATATTAA ATGAACACAGAGGAGAGAAGTTAAACAGGGTAAAGATGGTGGAAAAGGAAAAGGATGCCTTAGAAGGAGAGAAAAACATAGCTATCGAATTTCTTACCTT GGAAAATGAAATATTTAGAAAAAAGAATCATGTTTGTCAATATTATATTTATGAGTTGCAGAAACGAATTGCTGAAATGGAAACTCAAAAGGAAAAAATT CATGAAGATACCAAAGAAATTAATGAGAAGAGCAATATACTATCAAATGAAATGAAAGCTAAGAATAAAGATGTAAAAGATACAGAAAAGAAACTGAATA AAATTACAAAATTTATTGAGGAGAATAAAGAAAAATTTACACAGCTAGATTTGGAAGATGTTCAAGTTAGAGAAAAGTTAAAACATGCCACGAGTAAAGC CAAAAAACTGGAGAAACAACTTCAAAAAGATAAAGAAAAGGTTGAAGAATTTAAAAGTATACCTGCCAAGAGTAACAATATCATTAATGAAACAACAACC AGAAACAATGCCCTCGAGAAGGAAAAAGAGAAAGAAGAAAAAAAATTAAAGGAAGTTATGGATAGCCTTAAACAGGAAACACAAGGGCTTCAGAAAGAAA AAGAAAGTCGAGAGAAAGAACTTATGGGTTTCAGCAAATCGGTAAATGAAGCACGTTCAAAGATGGATGTAGCCCAGTCAGAACTTGATATCTATCTCAG TCGTCATAATACTGCAGTGTCTCAATTAACTAAGGCTAAGGAAGCTCTAATTGCAGCTTCTGAGACTCTCAAAGAAAGGAAAGCTGCAATCAGAGATATA GAAGGAAAACTCCCTCAAACTGAACAAGAATTAAAGGAGAAAGAAAAAGAACTTCAAAAACTTACACAAGAAGAAACAAACTTTAAAAGTTTGGTTCATG ATCTCTTTCAAAAAGTTGAAGAAGCAAAGAGCTCATTAGCAATGAATCGAAGTAGGGGGAAAGTCCTTGATGCAATAATTCAAGAAAAAAAATCTGGCAG GATTCCAGGAATATATGGAAGATTGGGGGACTTAGGAGCCATTGATGAAAAATACGACGTGGCTATATCATCCTGTTGTCATGCACTGGACTACATTGTT GTTGATTCTATTGATATAGCCCAAGAATGTGTAAACTTCCTTAAAAGACAAAATATTGGAGTTGCAACCTTTATAGGTTTAGATAAGATGGCTGTATGGG CGAAAAAGATGACCGAAATTCAAACTCCTGAAAATACTCCTCGTTTATTTGATTTAGTAAAAGTAAAAGATGAGAAAATTCGCCAAGCTTTTTATTTTGC TTTACGAGATACCTTAGTAGCTGACAACTTGGATCAAGCCACAAGAGTAGCATATCAAAAAGATAGAAGATGGAGAGTGGTAACTTTACAGGGACAAATC ATAGAACAGTCAGGTACAATGACTGGTGGTGGAAGCAAAGTAATGAAAGGAAGAATGGGTTCCTCACTTGTTATTGAAATCTCTGAAGAAGAGGTAAACA AAATGGAATCACAGTTGCAAAACGACTCTAAAAAAGCAATGCAAATCCAAGAACAGAAAGTACAACTTGAAGAAAGAGTAGTTAAGTTACGGCATAGTGA ACGAGAAATGAGGAACACACTAGAAAAATTTACTGCAAGCATCCAGCGTTTAATAGAGCAAGAAGAATATTTGAATGTCCAAGTTAAGGAACTTGAAGCT AATGTACTTGCTACAGCCCCTGACAAAAAAAAGCAGAAATTGCTAGAAGAAAACGTTAGTGCTTTCAAAACAGAATATGATGCTGTGGCTGAGAAAGCTG GTAAAGTAGAAGCTGAGGTTAAACGCTTACACAATACCATCGTAGAAATCAATAATCATAAACTCAAGGCCCAACAAGACAAACTTGATAAAATAAATAA GCAATTAGATGAATGTGCTTCTGCTATTACTAAAGCCCAAGTAGCAATCAAGACTGCTGACAGAAACCTTCAAAAGGCACAAGACTCTGTCTTGCGTACA GAGAAAGAAATAAAAGATACTGAGAAAGAGGTGGATGACCTAACAGCAGAGCTGAAAAGTCTTGAGGACAAAGCAGCAGAGGTCGTAAAGAATACAAATG CTGCAGAGGAATCCTTACCAGAGATCCAGAAAGAACATCGCAATCTGCTTCAAGAATTAAAAGTTATTCAAGAAAATGAACATGCTCTTCAAAAAGATGC ACTTAGTATTAAGTTGAAACTTGAACAAATAGATGGTCACATTGCTGAACATAATTCTAAAATAAAATATTGGCACAAAGAGATTTCAAAAATATCACTG CATCCTATAGAAGATAATCCTATTGAAGAGATTTCGGTTCTAAGCCCAGAGGATCTTGAAGCGATCAAGAATCCAGATTCTATAACAAATCAAATTGCAC TTTTGGAAGCCCGGTGTCATGAAATGAAACCAAACCTCGGTGCCATCGCAGAGTATAAAAAGAAGGAAGAATTGTATTTGCAACGGGTAGCAGAATTGGA CAAAATTACTTATGAAAGAGACAGTTTTAGACAGGCATATGAAGATCTTCGGAAACAAAGGCTTAATGAATTTATGGCAGGTTTTTATATAATAACAAAT AAATTAAAGGAAAATTACCAAATGCTTACTTTGGGAGGGGACGCCGAACTCGAGCTTGTAGACAGCTTGGATCCTTTCTCTGAAGGAATCATGTTCAGTG TTCGACCACCTAAGAAAAGTTGGAAAAAGATCTTCAACCTTTCGGGAGGAGAGAAAACACTTAGTTCATTGGCTTTAGTATTTGCTCTTCACCACTACAA GCCCACTCCCCTTTACTTCATGGATGAGATTGATGCAGCCCTTGATTTTAAAAATGTGTCCATTGTTGCATTTTATATATATGAACAAACAAAAAATGCA CAGTTCATAATAATTTCTCTTCGAAATAATATGTTTGAGATTTCGGATAGACTTATTGGAATTTACAAGACATACAACATAACAAAAAGTGTTGCTGTAA ATCCAAAAGAAATTGCATCTAAGGGACTTTGTTGAACTTTATGCTGAAGATTCTTCAAGTTGATTCAGTGTATTACTGATTTTTTTCTATTTGTAAAGGA TTATGAGTTGTATAAAATACATACTCCCTAAACTAGATCATGAAACTGGTTTCTGTTTTATGCAGTTGTCATTTGTAAAGTCTAATAAAATATTCTCTAT AATTGCTTCTAGATTACAAAAATATGACAATCTTGTAAGTAGCAGACTATGGAGAAAAATGAGTTACCTGGAGGGTCAGGTAACTTGCCAAACTAAAAAG TATGTTAGTTGAGGCAAAGTCCTAAGCAAGGTTGTGCTATCAAGGCTCAGCATACCTTCGTGGGCCTTTGATTTACCAACACTGGAAATGCCTGCCAACT AATCTTGGATAGATTCTTTAAGGCATTCCACTTAGCTTGCCAGTTGAGACAATCACCACAGTTATTACCCAAATACTATGAACATATTTTTGTAAACCAG TCATTCTGAATTATAGTGATGAGAATTTAAATATATGCTTTTCTAGAATTTGATGTTTGACCATTTATGACTTAATTACCAGAGAGCCAGTAAATTAGGA CAGTGTTTCAACAAGCCTAGGCTATCTCGTAAGTTGAAAAATATCCCACTATAGTTGCTTCATGAGTATGAAGTAAGATGGCCTCTGATTTACACTGGTT CAATTTACAAATTTTCAACTTTATGATAGGTTTATCCGGGTACTAAATGCATTTCAACTTGATAGTTTCAACTTATGATAGGTTTACCAGGATGTAGTCC CACTGTTGAGGAGCATCTATTTAGGGGTTAATTACTTTAGTAATAAGTGGAAAGTAAGATACCTTGAGTAATGTTTGCCTATAAAATTGTCAGCGTATTT TTACACTATTGGCTCAAGAATGTTATAATGCTAAGGGACATAAGTTGGCAACCACTTGGTTTTTGGAAGGACTTTCGGTATTGTATTAGAAGTCTGCCCT AGCTGTTAAATTTCTGGGTATTTATCCTAAGGAATTAATTAAAGAGTTAATTGTTCCTTTCTTCAGTGGGCCATTGTTTTAGATATTTAAAAAATCCAAC AGTTTCTATCATAATGTAACTGTAAAAATGTAAACACATTATTAGCATGGACTTTTAAATAAAGATTTAAAGAAAGCAA

refseq_SMC4.F2 (forward primer)
refseq_SMC4.R2 (reverse primer)
Alternative acceptor

Frame 0

QQTKQLLNR*LILRHV*IFPLT*VLLRNQSCLL ATRVFRWLPSRSPAASKRSVKRGSRKPVDRDFPG WGGRGVAARGLTCSRLSPGPSDHAP*RHPALHC PAQRGRAAAAVP*RRQQRRGA*AAVRPHGEPSH RRRDCK*GT***KFRRDFEQHSSSPASSNDQ*SW SSSAYDNSYCKPELQILCWGENSGTFP*ALFLY YRAKWQWQIQCY*FYAFCVWLSSTKNKI*KTLS INT*F**TQGHSELYSRSSFSKDN**GRG*L*SH S*Q*FLCIQNGLQR*YFCLSHKWKEKDI*GCWK SSSKPWN*LGP**IFNFTG*S*TNCYDETKRPD *TR*GYA*IFRRYNWLWTAK*TY*SLVSES*NIK *TQRREVKQGKDGGKGKGCLRRREKHSYRISYL GK*NI*KKESCLSILYL*VAETNC*NGNSKGKN S*RYQRN**EEQYTIK*NES*E*RCKRYRKETE* NYKIY*GE*RKIYTARFGRCSS*RKVKTCHE*S QKTGETTSKR*RKG*RI*KYTCQE*QYH**NNN QKQCPREGKRERRKKIKGSYG*P*TGNTRASERK RKSRERTYGFQQIGK*STFKDGCSPVRT*YLSQ SS*YCSVSIN*G*GSSNCSF*DSQRKESCNQRY RRKTPSN*TRIKGERKRTSKTYTRRNKL*KFGS* SLSKS*RSKELISNESK*GESP*CNNSRKKIWQ DSRNIWKIGGLRSH**KIRRGYIILLSCTGLHC C*FY*YSPRMCKLP*KTKYWSCNLYRFR*DGCMG EKDDRNSNS*KYSSFI*FSKSKR*ENSPSFLFC FTRYLSS*QLGSSHKSSISKR*KMESGNFTGTN HRTVRYNDWWWKQSNERKNGFLTCY*NL*RRGKQ NGITVAKRL*KSNANPRTESTT*RKSS*VTA** TRNEEHTRKIYCKHPAFNRARRIFECPS*GT*S *CTCYSP*QKKAEIARRKR*CFQNRI*CCG*ESW *SRS*G*TLTQYHRRNQ*S*TQGPTRQT**NK* AIR*MCFCYY*SPSSNQDC*QKPSKGTRLCLAY RERNKRY*ERGG*PNSRAEKS*GQSSRGRKEYKC CRGILTRDPERTSQSASRIKSYSRK*TCSSKRC T*Y*VET*TNRWSHC*T*F*NKILAQRDFKNIT ASYRR*SY*RDFGSKPRGS*SDQESRFYNKSNCT FGSPVS*NETKPRCHRRV*KEGRIVFATGSRIG QNYL*KRQF*TGI*RSSETKA**IYGRFLYNNK *IKGKLPNAYFGRGRRTRACRQLGSFL*RNHVQC STT*EKLEKDLQPFGRRENT*FIGFSICSSPLQ AHSPLLHG*D*CSP*F*KCVHCCILYI*TNKKC TVHNNFSSK*YV*DFG*TYWNLQDIQHNKKCCCK SKRNCI*GTLLNFMLKILQVDSVYY*FFSICKG L*VV*NTYSLN*IMKLVSVLCSCHL*SLIKYSL *LLLDYKNMTIL*VADYGEK*VTWRVR*LAKLKS MLVEAKS*ARLCYQGSAYLRGPLIYQHWKCLPT NLG*IL*GIPLSLPVETITTVITQIL*TYFCKP VILNYSDENLNICFSRI*CLTIYDLITREPVN*D SVSTSLGYLVS*KISHYSCFMSMK*DGL*FTLV QFTNFQLYDRFIRVLNAFQLDSFNL**VYQDVV PLLRSIYLGVNYFSNKWKVRYLE*CLPIKLSAYF YTIGSRML*C*GT*VGNHLVFGRTFGIVLEVCP SC*ISGYLS*GIN*RVNCSFLQWAIVLDI*KIQ QFLS*CNCKNVNTLLAWTFK*RFKES

Frame 1

NKLSSCSIVD*SSGTSRFSHLHRSC*ETSPAFL PLVSFDGSLPEVPLPLSGVLSGALGSRWTEISP GGAGAV*RPAG*LAPGCPPAPATMPRKGTQPSTA RRREEGPPPPSPDGASSDAEPEPPSGRTESPAT AAETASEELDNRSLEEILNSIPPPPPPAMTNEA GAPRLMITHIVNQNFKSYAGEKILGPFHKRFSCI IGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSV LIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEV IPNSNFYVSRTACRDNTSVYHISGKKKTFKDVGN LLRSHGIDLDHNRFLILQGEVEQIAMMKPKGQT EHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEIL NEHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTL ENEIFRKKNHVCQYYIYELQKRIAEMETQKEKI HEDTKEINEKSNILSNEMKAKNKDVKDTEKKLN KITKFIEENKEKFTQLDLEDVQVREKLKHATSKA KKLEKQLQKDKEKVEEFKSIPAKSNNIINETTT RNNALEKEKEKEEKKLKEVMDSLKQETQGLQKE KESREKELMGFSKSVNEARSKMDVAQSELDIYLS RHNTAVSQLTKAKEALIAASETLKERKAAIRDI EGKLPQTEQELKEKEKELQKLTQEETNFKSLVH DLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGR IPGIYGRLGDLGAIDEKYDVAISSCCHALDYIV VDSIDIAQECVNFLKRQNIGVATFIGLDKMAVW AKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFA LRDTLVADNLDQATRVAYQKDRRWRVVTLQGQI IEQSGTMTGGGSKVMKGRMGSSLVIEISEEEVN KMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSE REMRNTLEKFTASIQRLIEQEEYLNVQVKELEA NVLATAPDKKKQKLLEENVSAFKTEYDAVAEKA GKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINK QLDECASAITKAQVAIKTADRNLQKAQDSVLRT EKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTN AAEESLPEIQKEHRNLLQELKVIQENEHALQKDA LSIKLKLEQIDGHIAEHNSKIKYWHKEISKISL HPIEDNPIEEISVLSPEDLEAIKNPDSITNQIA LLEARCHEMKPNLGAIAEYKKKEELYLQRVAELD KITYERDSFRQAYEDLRKQRLNEFMAGFYIITN KLKENYQMLTLGGDAELELVDSLDPFSEGIMFS VRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYK PTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNA QFIIISLRNNMFEISDRLIGIYKTYNITKSVAV NPKEIASKGLC*TLC*RFFKLIQCITDFFLFVKD YELYKIHTP*TRS*NWFLFYAVVICKV**NILY NCF*ITKI*QSCK*QTMEKNELPGGSGNLPN*K VC*LRQSPKQGCAIKAQHTFVGL*FTNTGNACQL ILDRFFKAFHLACQLRQSPQLLPKYYEHIFVNQ SF*IIVMRI*IYAFLEFDV*PFMT*LPESQ*IR TVFQQA*AIS*VEKYPTIVAS*V*SKMASDLHWF NLQIFNFMIGLSGY*MHFNLIVSTYDRFTRM*S HC*GASI*GLITLVISGK*DTLSNVCL*NCQRI FTLLAQECYNAKGHKLATTWFLEGLSVLY*KSAL AVKFLGIYPKELIKELIVPFFSGPLF*IFKKSN SFYHNVTVKM*THY*HGLLNKDLKKA

Frame 2

TN*AVAQSLIDPQARLDFPTYIGLVKKPVLPSC HSCLSMAPFPKSRCL*AEC*AGLSEAGGPRFPR VGRARCSGPRADLLPAVPRPQRPCPVKAPSPPL PGAERKGRRRRPLTAPAATRSLSRRPAARRAQPP PQRLQVRNLIIEV*KRF*TAFLLPRLQQ*PMKL ELLGL**LIL*TRTSNPMLGRKFWDLSISAFPV LSGQMAVANPMLLILCFLCLAIEHKK*DLKNSQY *YIILMNTRTFRVVQ*KFIFKR*LIRKGMIMKS FLTVISMYPERPAEIILLSIT*VERKRHLRMLE IFFEAMELTWTIIDF*FYRVKLNKLL**NQKARL NTMRVCLNI*KI*LVVDG*MNLLKSCVGELKY* MNTEERS*TG*RWWKRKRMP*KERKT*LSNFLP WKMKYLEKRIMFVNIIFMSCRNELLKWKLKRKKF MKIPKKLMRRAIYYQMK*KLRIKM*KIQKRN*I KLQNLLRRIKKNLHS*IWKMFKLEKS*NMPRVK PKNWRNNFKKIKKRLKNLKVYLPRVTISLMKQQP ETMPSRRKKRKKKKN*RKLWIALNRKHKGFRKK KKVERKNLWVSANR*MKHVQRWM*PSQNLISIS VVIILQCLN*LRLRKL*LQLLRLSKKGKLQSEI* KENSLKLNKN*RRKKKNFKNLHKKKQTLKVWFM ISFKKLKKQRAH*Q*IEVGGKSLMQ*FKKKNLA GFQEYMEDWGT*EPLMKNTTWLYHPVVMHWTTLL LILLI*PKNV*TSLKDKILELQPL*V*IRWLYG RKR*PKFKLLKILLVYLI**K*KMRKFAKLFIL LYEIP**LTTWIKPQE*HIKKIEDGEW*LYRDKS *NSQVQ*LVVEAK**KEEWVPHLLLKSLKKR*T KWNHSCKTTLKKQCKSKNRKYNLKKE*LSYGIV NEK*GTH*KNLLQASSV**SKKNI*MSKLRNLKL MYLLQPLTKKSRNC*KKTLVLSKQNMMLWLRKL VK*KLRLNAYTIPS*KSIIINSRPNKTNLIK*I SN*MNVLLLLLKPK*QSRLLTETFKRHKTLSCVQ RKK*KILRKRWMT*QQS*KVLRTKQQRS*RIQM LQRNPYQRSRKNIAICFKN*KLFKKMNMLFKKM HLVLS*NLNK*MVTLLNIILK*NIGTKRFQKYHC IL*KIILLKRFRF*AQRILKRSRIQIL*QIKLH FWKPGVMK*NQTSVPSQSIKRRKNCICNG*QNW TKLLMKETVLDRHMKIFGNKGLMNLWQVFI**QI N*RKITKCLLWEGTPNSSL*TAWILSLKESCSV FDHLRKVGKRSSTFREERKHLVHWL*YLLFTTT SPLPFTSWMRLMQPLILKMCPLLHFIYMNKQKMH SS**FLFEIICLRFRIDLLEFTRHTT*QKVLL* IQKKLHLRDFVELYAEDSSS*FSVLLIFFYL*R IMSCIKYILPKLDHETGFCFMQLSFVKSNKIFSI IASRLQKYDNLVSSRLWRKMSYLEGQVTCQTKK YVS*GKVLSKVVLSRLSIPSWAFDLPTLEMPAN *SWIDSLRHST*LAS*DNHHSYYPNTMNIFL*TS HSEL***EFKYMLF*NLMFDHL*LNYQRASKLG QCFNKPRLSRKLKNIPL*LLHEYEVRWPLIYTG SIYKFSTL**VYPGTKCIST**FQLMIGLPGCSP TVEEHLFRG*LL***VESKIP*VMFAYKIVSVF LHYWLKNVIMLRDISWQPLGFWKDFRYCIRSLP *LLNFWVFILRN*LKS*LFLSSVGHCFRYLKNPT VSIIM*L*KCKHIISMDF*IKI*RKQ