Back to Rnomics Platform
Open Session
×
1 warning:
- Access restricted to public data.
Please sign in at Rnomics Platform to access your data.
Sequence NM_001018037
TTCCTCCCTCTCAGGGCTGCGCGCCCAGGTCTGCGCCGCGCTCCGCCTCCAGCCGCGCGCAGACTTGCGCACGCGTCGTGAGAGCGACCGCCTCCGTCTCTCGCTGGGCTCGCTAGGGCTGCGCGTTGGGCCAGCGGGGGCGCCGCAGCTGAAGCCGCCCCGGAGCCGGTGAACCGAATTACCTCGAGGGAGGGGCGTGG
GGAAGGCGGCGGGAGGAGGAGCGCACGGGCCGGCTGCCGTGCCCACCACGGCTGAGGAACATGGTTTTCGAGTCGGTGGTCGTGGACGTGTTGAACCGGT
TCTTGGGGGACTATGTGGTGGACTTGGACACGTCCCAGCTCTCTCTGGGCATCTGGAAAGGAGCTGTGGCCCTCAAGAATCTTCAAATTAAAGAAAATGC
CCTGAGTCAACTGGATGTACCATTTAAAGTTAAAGTTGGTCACATAGGTAATCTTAAACTTATAATTCCATGGAAAAACCTTTATACTCAACCTGTTGAA
GCCGTATTGGAAGAAATTTATTTACTTATAGTGCCTTCTTCTAGAATAAAATATGATCCTTTAAAAGAAGAGAAACAACTCATGGAAGCAAAGCAACAGG
AACTGAAAAGAATAGAAGAAGCAAAACAAAAAGTAGTTGATCAAGAACAACATCTGCCGGAAAAACAGGACACTTTTGCAGAAAAATTAGTTACACAGAT
CATAAAAAATCTTCAGGTGAAAATTTCCAGTATCCATATTCGTTATGAAGATGATATCACAAATCGGGACAAACCGCTGTCATTTGGTATTTCCCTTCAA
AATCTGAGCATGCAGACAACTGATCAATACTGGGTTCCATGTTTACATGATGAAACTGAGAAACTGGTTCGTAAGTTAATCCGATTGGATAACCTGTTTG
CCTATTGGAATGTGAAGTCTCAGATGTTTTATCTTAGTGATTATGATAACTCCTTGGACGACTTGAAGAATGGCATTGTCAATGAAAATATTGTTCCAGA
AGGTTATGATTTTGTATTTCGTCCCATATCTGCTAATGCCAAACTTGTGATGAATCGCCGATCTGATTTTGACTTTTCTGCCCCCAAAATAAACTTGGAA
ATTGAGTTACATAACATAGCAATTGAATTTAATAAACCACAGTATTTCAGTATTATGGAGCTTCTTGAATCAGTTGATATGATGGCACAAAATCTGCCAT
ATAGGAAGTTCAAACCTGATGTGCCTCTTCACCACCATGCCAGAGAATGGTGGGCTTATGCTATACATGGCGTTCTTGAAGTAAATGTTTGCCCCAGGTT
ATGGATGTGGTCATGGAAGCATATTAGAAAACATAGGCAAAAAGTGAAGCAATATAAAGAACTGTATAAAAAAAAGTTAACAAGTAAGAAGCCACCTGGT
GAACTTCTCGTGTCTTTGGAGGAGTTGGAAAAAACCTTGGATGTCTTTAATATAACTATAGCTAGACAGACGGCAGAAGTTGAGGTAAAGAAAGCTGGAT
ACAAAATTTACAAAGAAGGAGTAAAAGATCCAGAGGATAATAAAGGGTGGTTTAGCTGGCTATGGTCTTGGTCAGAACAAAATACTAATGAACAGCAACC
AGATGTTCAACCTGAAACTCTTGAAGAAATGTTGACACCTGAAGAAAAAGCTTTACTCTATGAAGCAATTGGCTATAGTGAAACAGCAGTTGATCCAACT
TTACTAAAAACATTTGAAGCCTTGAAGTTTTTTGTCCACTTGAAAAGTATGTCTATTGTTCTAAGAGAAAATCATCAAAAACCTGAGCTGGTAGATATTG
TAATAGAAGAATTTAGCACCTTAATTGTGCAAAGACCAGGAGCACAAGCAATAAAATTTGAAACTAAAATAGATTCATTTCATATTACTGGCTTACCAGA
TAATTCAGAAAAACCCCGCCTCCTGTCTTCATTGGATGATGCAATGTCACTTTTCCAAATTACATTTGAGATAAATCCATTAGATGAAACTGTTTCTCAG
AGGTGTATCATAGAAGCTGAACCTTTAGAAATCATATATGATGCAAGGACAGTGAATAGTATAGTGGAATTCTTCAGACCTCCAAAAGAGGTACATCTAG
CACAGCTCACTGCAGCAACTTTGACAAAACTGGAAGAATTTCGCAGTAAGACAGCAACAGGTCTACTGTATATTATTGAAACACAGAAAGTTCTTGATCT
CAAAATTAATTTGAAGGCTTCATATATTATTGTCCCACAAGATGGAATTTTTAGTCCTACATCAAATCTGCTTCTTTTGGACCTTGGTCATCTAAAGGTG
ACGAGTAAAAGTCGTTCTGAATTACCAGATGTGAAACAAGGTGAGGCCAATCTTAAAGAGATAATGGATAGAGCTTATGATTCATTTGATATTCAACTTA
CAAGTGTACAGCTGCTTTACAGTAGAGTTGGTGATAATTGGAGAGAAGCACGAAAACTCAGTGTATCTACCCAGCATATTTTGGTACCCATGCACTTCAA
TTTGGAACTGTCTAAGGCCATGGTTTTCATGGATGTAAGGATGCCCAAATTCAAGATTTATGGAAAGTTACCTCTTATTTCTTTACGAATCTCAGATAAA
AAACTACAAGGGATTATGGAATTGATTGAAAGCATTCCAAAACCTGAACCAGTAACTGAAGTATCTGCCCCTGTCAAATCATTCCAGATTCAAACATCTA
CTTCTTTGGGAACATCACAGATTTCACAGAAAATAATTCCTCTCTTGGAACTTCCATCTGTTTCTGAAGATGATTCAGAGGAGGAATTTTTTGATGCACC
ATGTAGTCCCTTGGAAGAACCTCTTCAGTTTCCAACTGGAGTTAAAAGTATTCGAACCAGAAAGTTACAAAAGCAGGATTGTTCAGTAAATATGACTACA
TTTAAAATAAGATTTGAAGTACCAAAGGTTTTGATCGAGTTTTATCACCTTGTTGGAGATTGTGAACTATCTGTGGTAGAAATTCTTGTTTTAGGATTGG
GTGCAGAAATTGAGATTAGAACATACGATTTGAAAGCAAATGCCTTTTTGAAAGAGTTCTGCTTAAAATGCCCAGAATACTTGGATGAAAACAAGAAACC
AGTTTATTTGGTTACAACCCTGGATAACACAATGGAAGACCTGTTAACGCTGGAATATGTAAAGGCTGAAAAGAATGTACCCGACTTGAAAAGTACCTAT
AACAATGTTTTACAATTGATTAAGGTAAATTTTTCCTCTTTGGATATTCATTTACACACTGAAGCACTTCTGAATACAATAAATTATCTTCATAATATCC
TTCCGCAATCAGAGGAAAAATCAGCCCCAGTGTCCACTACAGAGACTGAAGACAAAGGAGATGTCATTAAAAAATTAGGGCTTGATTCTGAGATGATTAT
GAGGCCTTCAGAAACTGAAATAAACGCAAAGCTAAGGAATATAATTGTTTTAGATTCTGATATAACAGCTATATACAAAAAGGCTGTTTATATCACTGGA
AAAGAAGTTTTCAGCTTCAAAATGGTTTCTTACATGGATGCAACTGCTGGTTCTGCATACACAGATATGAATGTGGTTGACATTCAGGTTAATTTAATAG
TTGGTTGCATTGAAGTAGTTTTTGTCACGAAATTTCTATATTCTATATTGGCTTTTATAGATAATTTTCAGGCAGCTAAACAAGCCTTGGCTGAGGCAAC
TGTTCAGGCAGCTGGAATGGCTGCTACTGGTGTAAAAGAACTCGCACAAAGGAGTTCCAGAATGGCACTGGATATTAACATCAAAGCCCCAGTTGTGGTC
ATCCCGCAGTCTCCAGTTTCTGAAAATGTTTTTGTTGCTGATTTTGGACTAATTACAATGACAAATACCTTTCATATGATAACAGAGAGCCAGAGCTCTC
CCCCACCTGTTATTGATTTGATAACAATAAAGCTGAGTGAAATGCGACTATACAGATCTCGATTTATTAATGATGCATACCAGGAAGTACTGGATCTACT
CCTGCCATTAAATCTTGAGGTTGTGGTTGAACGAAATTTATGCTGGGAGTGGTACCAGGAAGTTCCTTGTTTTAATGTAAATGCTCAGCTGAAACCAATG
GAGTTCATTCTTAGTCAAGAAGATATAACAACTATTTTTAAAACATTGCATGGCAATATATGGTATGAAAAAGATGGTAGTGCCTCACCTGCTGTAACAA
AAGACCAATACAGTGCCACTAGTGGAGTTACTACTAATGCTTCACACCATTCAGGAGGAGCAACTGTGGTGACAGCTGCTGTGGTAGAAGTACATTCACG
TGCCTTACTAGTTAAGACAACACTAAACATAAGCTTCAAAACTGATGATCTCACCATGGTGCTGTATAGTCCAGGTCCTAAACAGGCTTCCTTTACAGAT
GTTCGTGATCCTTCTCTGAAACTTGCTGAATTTAAATTGGAGAATATTATAAGTACTTTAAAAATGTATACAGATGGCTCAACATTTTCTTCCTTCTCAT
TAAAAAACTGTATTTTAGATGATAAAAGACCTCATGTCAAGAAAGCAACTCCTCGAATGATAGGACTGACAGTTGGTTTTGACAAAAAAGACATGATGGA
TATAAAGTACAGGAAAGTCAGAGATGGTTGTGTGACTGATGCGGTCTTTCAAGAAATGTATATTTGTGCAAGCGTAGAATTTCTGCAGACTGTTGCAAAT
GTCTTTCTTGAGGCCTACACCACAGGCACTGCTGTAGAAACCAGTGTGCAAACATGGACTGCTAAGGAAGAAGTACCTACACAGGAATCAGTGAAGTGGG
AAATTAATGTTATTATTAAAAATCCTGAAATTGTGTTTGTAGCTGACATGACAAAAAATGATGCTCCTGCTTTAGTCATTACAACACAATGTGAAATTTG
CTATAAAGGTAACCTTGAAAATAGTACAATGACTGCTGCCATTAAAGATCTCCAAGTGAGAGCCTGCCCGTTTCTTCCAGTCAAGAGAAAAGGCAAAATC
ACTACTGTTTTGCAGCCCTGTGACTTGTTTTATCAAACTACTCAGAAAGGTACAGATCCACAAGTGATCGATATGTCAGTAAAATCCCTGACACTAAAGG
TTTCACCAGTTATTATAAATACTATGATTACCATAACTTCAGCACTGTATACAACTAAGGAAACCATCCCAGAAGAAACGGCTTCTTCTACTGCACATTT
ATGGGAAAAGAAGGATACAAAGACTTTAAAAATGTGGTTTCTTGAAGAATCAAATGAAACTGAAAAAATAGCTCCCACAACTGAATTGGTACCCAAAGGC
GAGATGATAAAAATGAACATTGATTCTATTTTTATAGTTCTTGAGGCTGGAATTGGTCATAGAACAGTACCTATGCTTCTGGCAAAGTCACGTTTTTCAG
GGGAAGGCAAAAACTGGAGTTCCCTAATAAATCTGCACTGTCAGCTTGAGCTAGAAGTGCATTATTATAATGAAATGTTTGGTGTATGGGAGCCTTTGCT
TGAACCCTTAGAAATTGATCAGACTGAGGATTTTAGACCATGGAATCTTGGTATCAAGATGAAAAAGAAAGCAAAAATGGCCATTGTTGAGTCAGATCCT
GAAGAAGAAAACTACAAAGTGCCAGAATATAAAACTGTCATCAGTTTCCATTCAAAAGACCAATTAAACATTACATTATCCAAATGTGGTCTTGTAATGT
TAAACAATTTAGTCAAGGCATTTACAGAAGCTGCCACTGGATCTTCAGCTGACTTCGTAAAGGATCTAGCACCATTTATGATTTTAAATTCCCTTGGACT
TACTATTTCTGTTTCGCCAAGTGATTCTTTTAGTGTACTCAACATTCCTATGGCAAAATCATATGTATTGAAAAATGGAGAAAGTTTAAGTATGGATTAT
ATCCGAACCAAGGACAATGATCATTTCAATGCAATGACCAGCCTAAGCAGCAAACTCTTCTTCATTCTTCTTACACCTGTTAACCATTCTACTGCTGATA
AGATTCCTTTAACAAAAGTGGGACGACGTCTGTACACTGTAAGACACAGAGAGTCTGGCGTTGAAAGATCTATTGTTTGTCAAATTGATACAGTAGAAGG
AAGTAAGAAGGTCACAATTCGCTCCCCAGTGCAGATAAGAAATCATTTTTCAGTCCCACTGTCTGTTTACGAAGGGGATACCTTATTGGGAACTGCCTCA
CCTGAAAATGAATTCAACATACCATTAGGATCTTACCGATCATTCATTTTTCTGAAGCCAGAAGATGAGAACTATCAAATGTGTGAAGGAATTGACTTTG
AAGAGATTATAAAAAATGATGGTGCTCTTCTAAAGAAGAAATGTAGATCTAAAAACCCTTCTAAGGAATCATTTCTCATTAATATTGTTCCAGAAAAAGA
TAATTTAACATCTCTATCAGTGTATTCAGAAGATGGTTGGGATTTACCATACATAATGCATTTGTGGCCACCTATCCTGCTCCGAAATCTTCTTCCTTAC
AAAATTGCTTATTATATAGAGGGAATTGAAAATTCGGTTTTTACTCTAAGTGAAGGACATTCAGCCCAGATTTGTACTGCACAGTTGGGTAAAGCCAGGC
TACATTTAAAATTACTTGACTATCTCAATCACGATTGGAAAAGTGAATATCACATAAAGCCTAATCAGCAAGACATTAGTTTTGTCAGTTTTACTTGTGT
TACAGAAATGGAAAAGACTGATTTAGATATTGCTGTCCATATGACTTACAATACTGGTCAGACAGTTGTGGCATTTCATAGTCCTTATTGGATGGTCAAT
AAAACTGGCCGCATGTTACAGTACAAAGCAGACGGAATTCATCGAAAGCATCCACCTAATTATAAAAAGCCAGTTCTCTTTTCTTTTCAGCCAAATCACT
TTTTTAATAACAATAAGGTTCAACTTATGGTAACTGATAGTGAGTTGTCCAATCAGTTTTCAATTGATACTGTTGGTAGTCATGGAGCTGTTAAATGTAA
AGGCCTGAAAATGGACTATCAAGTTGGTGTCACTATAGACCTGAGCAGTTTTAACATTACTAGAATTGTGACATTTACCCCTTTTTATATGATTAAAAAC
AAAAGCAAATACCATATATCAGTGGCTGAAGAAGGAAATGATAAATGGCTCTCTCTTGATTTGGAGCAGTGTATCCCCTTTTGGCCTGAGTATGCTTCTA
GTAAACTTCTTATTCAAGTCGAAAGGAGTGAAGATCCTCCCAAAAGGATATATTTTAACAAGCAGGAAAATTGTATTCTATTGCGTCTAGATAACGAGCT
TGGAGGTATTATAGCAGAAGTGAATTTGGCCGAGCATTCTACAGTTATTACATTTTTAGATTATCATGATGGAGCAGCTACATTCCTCTTAATAAATCAC
ACAAAGAATGAACTTGTTCAATACAATCAAAGTTCTCTCAGTGAAATAGAAGATTCCCTCCCTCCTGGTAAAGCCGTGTTTTATACATGGGCTGATCCGG
TGGGCTCTAGAAGGCTGAAGTGGAGATGTAGAAAAAGCCATGGTGAAGTAACACAGAAGGATGATATGATGATGCCTATAGATTTGGGGGAAAAGACAAT
ATATTTAGTTTCATTCTTTGAAGGTTTACAACGCATTATTTTATTCACTGAAGATCCAAGGGTATTTAAAGTAACATATGAAAGTGAGAAAGCAGAGTTA
GCAGAGCAAGAAATTGCAGTGGCATTACAAGATGTTGGAATTTCTCTTGTCAACAATTACACGAAGCAAGAAGTAGCCTATATAGGCATTACAAGTTCTG
ATGTGGTTTGGGAAACAAAGCCCAAGAAGAAGGCAAGATGGAAGCCAATGAGTGTAAAGCACACTGAGAAGTTAGAGAGAGAATTTAAGGAATATACTGA
ATCTTCTCCTTCAGAAGATAAGGTTATTCAGTTGGACACTAATGTTCCGGTTCGCCTAACCCCTACTGGTCATAACATGAAAATTCTGCAGCCGCATGTA
ATAGCTCTACGAAGAAATTATCTTCCAGCATTAAAAGTGGAATATAACACATCTGCACATCAATCATCATTTAGAATTCAGATTTACAGAATACAGATCC
AAAATCAGATACATGGTGCTGTATTTCCCTTTGTGTTTTATCCTGTTAAACCTCCAAAGTCGGTCACCATGGATTCAGCACCAAAGCCCTTTACAGATGT
CAGTATTGTCATGAGATCTGCAGGACATTCCCAGATATCACGTATTAAGTATTTCAAAGTATTGATTCAAGAAATGGATCTCAGGTTAGATCTTGGGTTT
ATCTATGCTTTAACAGACCTTATGACAGAAGCTGAGGTGACTGAAAATACAGAGGTTGAGCTTTTTCATAAAGATATAGAAGCTTTCAAAGAAGAATATA
AAACAGCCTCATTAGTAGATCAATCACAAGTCAGCCTCTATGAATATTTTCATATATCTCCTATCAAGTTACATTTAAGTGTTTCACTGAGTTCCGGCAG
AGAAGAAGCTAAAGATTCAAAACAAAATGGAGGACTGATTCCAGTTCATTCTTTAAATCTTTTGCTGAAGAGTATTGGTGCCACACTGACAGATGTACAA
GATGTAGTTTTTAAGCTTGCATTTTTTGAACTCAACTATCAGTTCCATACAACATCCGATCTACAGTCTGAAGTCATAAGACACTATTCAAAACAGGCCA
TTAAGCAGATGTATGTACTCATTCTTGGACTTGATGTTTTGGGAAATCCATTTGGCTTAATTAGAGAATTTTCTGAAGGTGTAGAAGCATTTTTTTATGA
ACCTTACCAGGGAGCCATCCAGGGTCCTGAAGAGTTTGTGGAAGGAATGGCACTAGGACTTAAGGCACTAGTTGGTGGAGCTGTTGGTGGATTGGCTGGT
GCTGCCTCCAAAATCACCGGTGCTATGGCTAAGGGGGTAGCAGCTATGACCATGGATGAAGACTACCAACAGAAGAGAAGAGAAGCCATGAATAAGCAAC
CAGCTGGTTTTAGAGAAGGCATCACTCGTGGAGGAAAAGGCTTAGTTTCTGGATTTGTTAGTGGCATAACAGGAATTGTTACAAAACCAATCAAAGGAGC
TCAAAAAGGAGGAGCAGCTGGTTTCTTTAAAGGTGTTGGGAAAGGTTTAGTAGGAGCGGTAGCAAGGCCAACTGGAGGCATCATAGACATGGCTAGCAGT
ACATTTCAGGGAATAAAAAGAGCTACAGAGACTTCTGAAGTGGAGAGTCTGCGACCTCCTCGGTTCTTCAATGAAGATGGAGTTATCAGACCGTACAGGT
TGAGGGATGGGACTGGAAATCAAATGTTACAGGTCATGGAAAATGGAAGATTTGCAAAATACAAATATTTTACCCATGTCATGATCAATAAGACAGATAT
GCTAATGATAACCAGACGTGGTGTATTGTTTGTAACAAAGGGAACATTTGGACAACTCACGTGTGAGTGGCAGTATAGTTTTGATGAATTTACCAAAGAG
CCATTCATTGTTCATGGGAGAAGATTGCGCATTGAAGCAAAGGAACGAGTGAAGTCTGTATTTCATGCCAGAGAGTTTGGAAAAATAATTAACTTCAAGA
CCCCAGAGGATGCCAGGTGGATCCTCACAAAGCTACAAGAAGCAAGAGAACCTTCTCCGAGCCTCTGACAGAGAACACTGCCTGAAGACACACAGCAATA
AGTGATTACAGCTCCTAGACTACCTTCCAAAACCTGTTTGGGAAGCATATTACAGAAATGATTTCAAGTACCCTGTATTCTGGATGCTAAAAAACAAAAA
CAAACAAAAAAACAAAAACAAAAAAACAAAACCAGAATCAGGTAAAACAGCTATGTGATTAAAATATTTTAATTCTTCAGCAATTACCCGGTTTTCTAAA
TTGAATCATGCATCTATTTATAATTCTAATTATTTTGTAAAAGAAGACAAAATTATGAATCTTAAGTATTTGCTCCATCTTTTTCTCTGTAATGGTGGAG
AGGCTGCCCATAATTCATCTCCACATGGAGCCAAGTTTAATGTTTCTAGTTCACATTTTGTACTTCTGTCATGCTTATTTCAAACTCCCTGAGTGATGGG
TAAGAAATCAAACATTGCCTCAGTGGTATCAAGAGAACTTTGGTGGTGGTTTCTTCAGAATCATGAAGTTCTTTTGCCAGATAAATATTTTGATATTATT
TTCCTTTTTAATATAAAGGATAGGTTTGAATTGTACTTAAAATGCATAGCATTATTAAAAACAATCTTTTAAAATATAATTTATAACATAGATTGAAGCC
TCCCCTTAAGAAACCTTAAAGAAATAAGTATCCTACTCAAAAAAGGAAGTCTGTTTCAGAACTTTAGGGCCTTTGAAATATTTCCTCAAGCCTATTTCAT
GAGATCTACTTGGTTTACCCAAGTCATGTTTTTAATAGACTGCTAATATCAAAGGAGAATTTTTAAAGCCTTAACAATGCCTACTTTCCATTCACTGTTA
ACATGGAATAAACACAATTCCCAACATCTTAGATAGTGTATTATGCTTCCAACAGACAGTCCCTCTCATATAAAGTTTATGTACCCTAAAATCTAACCCA
ATAACCTGTCCCGTTGCCAATAGATTGAGAATTTCTGGTTTGCTTACTCTACAGTTATTCAAATGAGAGTCACGCTTTTAAATTTACAGCTCATCACAGA
AATCATCAGCTATACATTAGTAAAAATAAGGACATGAGGTTTTCTTTCTTGGTTTTTGTCCAAGATCTTTGCACCTTAATATTAATGGACTGTTTCAGGT
AAAAGAGAATGAATGTATGATTGTGAACTGTGAAGAGAATGATGCAGGATCCTATTTAGTTACTGAATAATACAGAGTATTCAATGCATGTTGTATGTGC
CACCAAGTTACTATTAACTGTTTTTGGAATTGAAGACTCTGTATAGTCAATAGTTGTGAAATTCTTCTCAGGCTCCTTAAACCCTCGCTTTGTTGTAAAA
GCTAAAATAAACAGCATGCTATATTGTAATTGTATTTCTTGCTGACCAAATCTACTAAATGCTATTGATTTCTCTCTGATTACTAAAACACATTGTTTAT
TCTCAGTAGTTTCCCCCAAAATGCTTTTTTCTTTGCTGAACTTAA
- refseq_VPS13A.F1 (forward primer)
- refseq_VPS13A.R1 (reverse primer)
- Single exon skipping
Frame 0
FLPLRAARPGLRRAPPPAARRLAHAS*ERPPPSLAGLARAARWASGGAAAEAAPEPVNRITSREGRG
EGGGRRSARAGCRAHHG*GTWFSSRWSWTC*TG
SWGTMWWTWTRPSSLWASGKELWPSRIFKLKKM
P*VNWMYHLKLKLVT*VILNL*FHGKTFILNLLK
PYWKKFIYL*CLLLE*NMIL*KKRNNSWKQSNR
N*KE*KKQNKK*LIKNNICRKNRTLLQKN*LHR
S*KIFR*KFPVSIFVMKMISQIGTNRCHLVFPFK
I*ACRQLINTGFHVYMMKLRNWFVS*SDWITCL
PIGM*SLRCFILVIMITPWTT*RMALSMKILFQ
KVMILYFVPYLLMPNL**IADLILTFLPPK*TWK
LSYIT*QLNLINHSISVLWSFLNQLI*WHKICH
IGSSNLMCLFTTMPENGGLMLYMAFLK*MFAPG
YGCGHGSILENIGKK*SNIKNCIKKS*QVRSHLV
NFSCLWRSWKKPWMSLI*L*LDRRQKLR*RKLD
TKFTKKE*KIQRIIKGGLAGYGLGQNKILMNSN
QMFNLKLLKKC*HLKKKLYSMKQLAIVKQQLIQL
Y*KHLKP*SFLST*KVCLLF*EKIIKNLSW*IL
**KNLAP*LCKDQEHKQ*NLKLK*IHFILLAYQ
IIQKNPASCLHWMMQCHFSKLHLR*IH*MKLFLR
GVS*KLNL*KSYMMQGQ*IV*WNSSDLQKRYI*
HSSLQQL*QNWKNFAVRQQQVYCILLKHRKFLI
SKLI*RLHILLSHKMEFLVLHQICFFWTLVI*R*
RVKVVLNYQM*NKVRPILKR*WIELMIHLIFNL
QVYSCFTVELVIIGEKHENSVYLPSIFWYPCTS
IWNCLRPWFSWM*GCPNSRFMESYLLFLYESQIK
NYKGLWN*LKAFQNLNQ*LKYLPLSNHSRFKHL
LLWEHHRFHRK*FLSWNFHLFLKMIQRRNFLMH
HVVPWKNLFSFQLELKVFEPESYKSRIVQ*I*LH
LK*DLKYQRF*SSFITLLEIVNYLW*KFLF*DW
VQKLRLEHTI*KQMPF*KSSA*NAQNTWMKTRN
QFIWLQPWITQWKTC*RWNM*RLKRMYPT*KVPI
TMFYN*LR*IFPLWIFIYTLKHF*IQ*IIFIIS
FRNQRKNQPQCPLQRLKTKEMSLKN*GLILR*L
*GLQKLK*TQS*GI*LF*ILI*QLYTKRLFISLE
KKFSASKWFLTWMQLLVLHTQI*MWLTFRLI**
LVALK*FLSRNFYILYWLL*IIFRQLNKPWLRQ
LFRQLEWLLLV*KNSHKGVPEWHWILTSKPQLWS
SRSLQFLKMFLLLILD*LQ*QIPFI**QRARAL
PHLLLI**Q*S*VKCDYTDLDLLMMHTRKYWIY
SCH*ILRLWLNEIYAGSGTRKFLVLM*MLS*NQW
SSFLVKKI*QLFLKHCMAIYGMKKMVVPHLL*Q
KTNTVPLVELLLMLHTIQEEQLW*QLLW*KYIH
VPY*LRQH*T*ASKLMISPWCCIVQVLNRLPLQM
FVILL*NLLNLNWRIL*VL*KCIQMAQHFLPSH
*KTVF*MIKDLMSRKQLLE**D*QLVLTKKT*W
I*STGKSEMVV*LMRSFKKCIFVQA*NFCRLLQM
SFLRPTPQALL*KPVCKHGLLRKKYLHRNQ*SG
KLMLLLKILKLCL*LT*QKMMLLL*SLQHNVKF
AIKVTLKIVQ*LLPLKISK*EPARFFQSREKAKS
LLFCSPVTCFIKLLRKVQIHK*SICQ*NP*H*R
FHQLL*IL*LP*LQHCIQLRKPSQKKRLLLLHI
YGKRRIQRL*KCGFLKNQMKLKK*LPQLNWYPKA
R**K*TLILFL*FLRLELVIEQYLCFWQSHVFQ
GKAKTGVP**ICTVSLS*KCIIIMKCLVYGSLC
LNP*KLIRLRILDHGILVSR*KRKQKWPLLSQIL
KKKTTKCQNIKLSSVSIQKTN*TLHYPNVVL*C
*TI*SRHLQKLPLDLQLTS*RI*HHL*F*IPLD
LLFLFRQVILLVYSTFLWQNHMY*KMEKV*VWII
SEPRTMIISMQ*PA*AANSSSFFLHLLTILLLI
RFL*QKWDDVCTL*DTESLALKDLLFVKLIQ*K
EVRRSQFAPQCR*EIIFQSHCLFTKGIPYWELPH
LKMNSTYH*DLTDHSFF*SQKMRTIKCVKELTL
KRL*KMMVLF*RRNVDLKTLLRNHFSLILFQKK
II*HLYQCIQKMVGIYHT*CICGHLSCSEIFFLT
KLLII*RELKIRFLL*VKDIQPRFVLHSWVKPG
YI*NYLTISITIGKVNIT*SLISKTLVLSVLLV
LQKWKRLI*ILLSI*LTILVRQLWHFIVLIGWSI
KLAACYSTKQTEFIESIHLIIKSQFSFLFSQIT
FLITIRFNLW*LIVSCPISFQLILLVVMELLNV
KA*KWTIKLVSL*T*AVLTLLEL*HLPLFI*LKT
KANTIYQWLKKEMINGSLLIWSSVSPFGLSMLL
VNFLFKSKGVKILPKGYILTSRKIVFYCV*ITS
LEVL*QK*IWPSILQLLHF*IIMMEQLHSS**IT
QRMNLFNTIKVLSVK*KIPSLLVKPCFIHGLIR
WALEG*SGDVEKAMVK*HRRMI**CL*IWGKRQ
YI*FHSLKVYNALFYSLKIQGYLK*HMKVRKQS*
QSKKLQWHYKMLEFLLSTITRSKK*PI*ALQVL
MWFGKQSPRRRQDGSQ*V*STLRS*RENLRNIL
NLLLQKIRLFSWTLMFRFA*PLLVIT*KFCSRM*
*LYEEIIFQH*KWNITHLHINHHLEFRFTEYRS
KIRYMVLYFPLCFILLNLQSRSPWIQHQSPLQM
SVLS*DLQDIPRYHVLSISKY*FKKWISG*ILGL
SML*QTL*QKLR*LKIQRLSFFIKI*KLSKKNI
KQPH**INHKSASMNIFIYLLSSYI*VFH*VPA
EKKLKIQNKMED*FQFIL*IFC*RVLVPH*QMYK
M*FLSLHFLNSTISSIQHPIYSLKS*DTIQNRP
LSRCMYSFLDLMFWEIHLA*LENFLKV*KHFFM
NLTREPSRVLKSLWKEWH*DLRH*LVELLVDWLV
LPPKSPVLWLRG*QL*PWMKTTNRREEKP*ISN
QLVLEKASLVEEKA*FLDLLVA*QELLQNQSKE
LKKEEQLVSLKVLGKV**ER*QGQLEAS*TWLAV
HFRE*KELQRLLKWRVCDLLGSSMKMELSDRTG
*GMGLEIKCYRSWKMEDLQNTNILPMS*SIRQI
C***PDVVYCL*QREHLDNSRVSGSIVLMNLPKS
HSLFMGEDCALKQRNE*SLYFMPESLEK*LTSR
PQRMPGGSSQSYKKQENLLRASDREHCLKTHSN
K*LQLLDYLPKPVWEAYYRNDFKYPVFWMLKNKN
KQKNKNKKTKPESGKTAM*LKYFNSSAITRFSK
LNHASIYNSNYFVKEDKIMNLKYLLHLFLCNGG
EAAHNSSPHGAKFNVSSSHFVLLSCLFQTP*VMG
KKSNIASVVSRELWWWFLQNHEVLLPDKYFDII
FLFNIKDRFELYLKCIALLKTIF*NIIYNID*S
LPLRNLKEISILLKKGSLFQNFRAFEIFPQAYFM
RSTWFTQVMFLIDC*YQRRIFKALTMPTFHSLL
TWNKHNSQHLR*CIMLPTDSPSHIKFMYPKI*P
NNLSRCQ*IENFWFAYSTVIQMRVTLLNLQLITE
IISYTLVKIRT*GFLSWFLSKIFAP*Y*WTVSG
KRE*MYDCEL*RE*CRILFSY*IIQSIQCMLYV
PPSYY*LFLELKTLYSQ*L*NSSQAP*TLALL*K
LK*TACYIVIVFLADQIY*MLLISL*LLKHIVY
SQ*FPPKCFFLC*T*
Frame 1
SSLSGLRAQVCAALRLQPRADLRTRRESDRLRLSLGSLGLRVGPAGAPQLKPPRSR*TELPRGRGV
GKAAGGGAHGPAAVPTTAEEHGFRVGGRGRVEPV
LGGLCGGLGHVPALSGHLERSCGPQESSN*RKC
PESTGCTI*S*SWSHR*S*TYNSMEKPLYSTC*
SRIGRNLFTYSAFF*NKI*SFKRRETTHGSKATG
TEKNRRSKTKSS*SRTTSAGKTGHFCRKISYTD
HKKSSGENFQYPYSL*R*YHKSGQTAVIWYFPS
KSEHADN*SILGSMFT**N*ETGS*VNPIG*PVC
LLECEVSDVLS**L**LLGRLEEWHCQ*KYCSR
RL*FCISSHIC*CQTCDESPI*F*LFCPQNKLG
N*VT*HSN*I**TTVFQYYGAS*IS*YDGTKSAI
*EVQT*CASSPPCQRMVGLCYTWRS*SKCLPQV
MDVVMEAY*KT*AKSEAI*RTV*KKVNK*EATW
*TSRVFGGVGKNLGCL*YNYS*TDGRS*GKESWI
QNLQRRSKRSRG**RVV*LAMVLVRTKY**TAT
RCST*NS*RNVDT*RKSFTL*SNWL**NSS*SN
FTKNI*SLEVFCPLEKYVYCSKRKSSKT*AGRYC
NRRI*HLNCAKTRSTSNKI*N*NRFISYYWLTR
*FRKTPPPVFIG*CNVTFPNYI*DKSIR*NCFS
EVYHRS*TFRNHI*CKDSE*YSGILQTSKRGTSS
TAHCSNFDKTGRISQ*DSNRSTVYY*NTESS*S
QN*FEGFIYYCPTRWNF*SYIKSASFGPWSSKG
DE*KSF*ITRCETR*GQS*RDNG*SL*FI*YSTY
KCTAALQ*SW**LERSTKTQCIYPAYFGTHALQ
FGTV*GHGFHGCKDAQIQDLWKVTSYFFTNLR*
KTTRDYGID*KHSKT*TSN*SICPCQIIPDSNIY
FFGNITDFTENNSSLGTSICF*R*FRGGIF*CT
M*SLGRTSSVSNWS*KYSNQKVTKAGLFSKYDY
I*NKI*STKGFDRVLSPCWRL*TICGRNSCFRIG
CRN*D*NIRFESKCLFERVLLKMPRILG*KQET
SLFGYNPG*HNGRPVNAGICKG*KECTRLEKYL
*QCFTID*GKFFLFGYSFTH*STSEYNKLSS*YP
SAIRGKISPSVHYRD*RQRRCH*KIRA*F*DDY
EAFRN*NKRKAKEYNCFRF*YNSYIQKGCLYHW
KRSFQLQNGFLHGCNCWFCIHRYECG*HSG*FNS
WLH*SSFCHEISIFYIGFYR*FSGS*TSLG*GN
CSGSWNGCYWCKRTRTKEFQNGTGY*HQSPSCG
HPAVSSF*KCFCC*FWTNYNDKYLSYDNREPELS
PTCY*FDNNKAE*NATIQISIY**CIPGSTGST
PAIKS*GCG*TKFMLGVVPGSSLF*CKCSAETN
GVHS*SRRYNNYF*NIAWQYMV*KRW*CLTCCNK
RPIQCH*WSYY*CFTPFRRSNCGDSCCGRSTFT
CLTS*DNTKHKLQN**SHHGAV*SRS*TGFLYR
CS*SFSETC*I*IGEYYKYFKNVYRWLNIFFLLI
KKLYFR**KTSCQESNSSNDRTDSWF*QKRHDG
YKVQESQRWLCD*CGLSRNVYLCKRRISADCCK
CLS*GLHHRHCCRNQCANMDC*GRSTYTGISEVG
N*CYY*KS*NCVCS*HDKK*CSCFSHYNTM*NL
L*R*P*K*YNDCCH*RSPSESLPVSSSQEKRQN
HYCFAAL*LVLSNYSERYRSTSDRYVSKIPDTKG
FTSYYKYYDYHNFSTVYN*GNHPRRNGFFYCTF
MGKEGYKDFKNVVS*RIK*N*KNSSHN*IGTQR
RDDKNEH*FYFYSS*GWNWS*NSTYASGKVTFFR
GRQKLEFPNKSALSA*ARSALL**NVWCMGAFA
*TLRN*SD*GF*TMESWYQDEKESKNGHC*VRS
*RRKLQSARI*NCHQFPFKRPIKHYIIQMWSCNV
KQFSQGIYRSCHWIFS*LRKGSSTIYDFKFPWT
YYFCFAK*FF*CTQHSYGKIICIEKWRKFKYGL
YPNQGQ*SFQCNDQPKQQTLLHSSYTC*PFYC**
DSFNKSGTTSVHCKTQRVWR*KIYCLSN*YSRR
K*EGHNSLPSADKKSFFSPTVCLRRGYLIGNCL
T*K*IQHTIRILPIIHFSEARR*ELSNV*RN*L*
RDYKK*WCSSKEEM*I*KPF*GIISH*YCSRKR
*FNISISVFRRWLGFTIHNAFVATYPAPKSSSL
QNCLLYRGN*KFGFYSK*RTFSPDLYCTVG*SQA
TFKIT*LSQSRLEK*ISHKA*SARH*FCQFYLC
YRNGKD*FRYCCPYDLQYWSDSCGIS*SLLDGQ
*NWPHVTVQSRRNSSKAST*L*KASSLFFSAKSL
F**Q*GSTYGN***VVQSVFN*YCW*SWSC*M*
RPENGLSSWCHYRPEQF*HY*NCDIYPFLYD*K
QKQIPYISG*RRK**MALS*FGAVYPLLA*VCF*
*TSYSSRKE*RSSQKDIF*QAGKLYSIASR*RA
WRYYSRSEFGRAFYSYYIFRLS*WSSYIPLNKS
HKE*TCSIQSKFSQ*NRRFPPSW*SRVLYMG*SG
GL*KAEVEM*KKPW*SNTEG*YDDAYRFGGKDN
IFSFIL*RFTTHYFIH*RSKGI*SNI*K*ESRV
SRARNCSGITRCWNFSCQQLHEARSSLYRHYKF*
CGLGNKAQEEGKMEANECKAH*EVRERI*GIY*
IFSFRR*GYSVGH*CSGSPNPYWS*HENSAAAC
NSSTKKLSSSIKSGI*HICTSIII*NSDLQNTDP
KSDTWCCISLCVLSC*TSKVGHHGFSTKALYRC
QYCHEICRTFPDITY*VFQSIDSRNGSQVRSWV
YLCFNRPYDRS*GD*KYRG*AFS*RYRSFQRRI*
NSLISRSITSQPL*IFSYISYQVTFKCFTEFRQ
RRS*RFKTKWRTDSSSFFKSFAEEYWCHTDRCT
RCSF*ACIF*TQLSVPYNIRSTV*SHKTLFKTGH
*ADVCTHSWT*CFGKSIWLN*RIF*RCRSIFL*
TLPGSHPGS*RVCGRNGTRT*GTSWWSCWWIGW
CCLQNHRCYG*GGSSYDHG*RLPTEEKRSHE*AT
SWF*RRHHSWRKRLSFWIC*WHNRNCYKTNQRS
SKRRSSWFL*RCWERFSRSGSKANWRHHRHG*Q
YISGNKKSYRDF*SGESATSSVLQ*RWSYQTVQV
EGWDWKSNVTGHGKWKICKIQIFYPCHDQ*DRY
ANDNQTWCIVCNKGNIWTTHV*VAV*F**IYQR
AIHCSWEKIAH*SKGTSEVCISCQRVWKNN*LQD
PRGCQVDPHKATRSKRTFSEPLTENTA*RHTAI
SDYSS*TTFQNLFGKHITEMISSTLYSGC*KTK
TNKKTKTKKQNQNQVKQLCD*NILILQQLPGFLN
*IMHLFIILIIL*KKTKL*ILSICSIFFSVMVE
RLPIIHLHMEPSLMFLVHILYFCHAYFKLPE*W
VRNQTLPQWYQENFGGGFFRIMKFFCQINILILF
SFLI*RIGLNCT*NA*HY*KQSFKI*FIT*IEA
SP*ETLKK*VSYSKKEVCFRTLGPLKYFLKPIS
*DLLGLPKSCF**TANIKGEFLKP*QCLLSIHC*
HGINTIPNILDSVLCFQQTVPLI*SLCTLKSNP
ITCPVANRLRISGLLTLQLFK*ESRF*IYSSSQ
KSSAIH**K*GHEVFFLGFCPRSLHLNINGLFQV
KENECMIVNCEENDAGSYLVTE*YRVFNACCMC
HQVTINCFWN*RLCIVNSCEILLRLLKPSLCCK
S*NKQHAIL*LYFLLTKSTKCY*FLSDY*NTLFI
LSSFPQNAFFFAEL
Frame 2
PPSQGCAPRSAPRSASSRAQTCARVVRATASVSRWAR*GCALGQRGRRS*SRPGAGEPNYLEGGAW
GRRREEERTGRLPCPPRLRNMVFESVVVDVLNR
FLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENA
LSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVE
AVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQ
ELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQI
IKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ
NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLF
AYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPE
GYDFVFRPISANAKLVMNRRSDFDFSAPKINLE
IELHNIAIEFNKPQYFSIMELLESVDMMAQNLP
YRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRL
WMWSWKHIRKHRQKVKQYKELYKKKLTSKKPPG
ELLVSLEELEKTLDVFNITIARQTAEVEVKKAG
YKIYKEGVKDPEDNKGWFSWLWSWSEQNTNEQQP
DVQPETLEEMLTPEEKALLYEAIGYSETAVDPT
LLKTFEALKFFVHLKSMSIVLRENHQKPELVDI
VIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPD
NSEKPRLLSSLDDAMSLFQITFEINPLDETVSQ
RCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHL
AQLTAATLTKLEEFRSKTATGLLYIIETQKVLDL
KINLKASYIIVPQDGIFSPTSNLLLLDLGHLKV
TSKSRSELPDVKQGEANLKEIMDRAYDSFDIQL
TSVQLLYSRVGDNWREARKLSVSTQHILVPMHFN
LELSKAMVFMDVRMPKFKIYGKLPLISLRISDK
KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTS
TSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAP
CSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTT
FKIRFEVPKVLIEFYHLVGDCELSVVEILVLGL
GAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKP
VYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTY
NNVLQLIKVNFSSLDIHLHTEALLNTINYLHNI
LPQSEEKSAPVSTTETEDKGDVIKKLGLDSEMIM
RPSETEINAKLRNIIVLDSDITAIYKKAVYITG
KEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLI
VGCIEVVFVTKFLYSILAFIDNFQAAKQALAEAT
VQAAGMAATGVKELAQRSSRMALDINIKAPVVV
IPQSPVSENVFVADFGLITMTNTFHMITESQSS
PPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLL
LPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPM
EFILSQEDITTIFKTLHGNIWYEKDGSASPAVT
KDQYSATSGVTTNASHHSGGATVVTAAVVEVHSR
ALLVKTTLNISFKTDDLTMVLYSPGPKQASFTD
VRDPSLKLAEFKLENIISTLKMYTDGSTFSSFS
LKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMD
IKYRKVRDGCVTDAVFQEMYICASVEFLQTVAN
VFLEAYTTGTAVETSVQTWTAKEEVPTQESVKW
EINVIIKNPEIVFVADMTKNDAPALVITTQCEIC
YKGNLENSTMTAAIKDLQVRACPFLPVKRKGKI
TTVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLK
VSPVIINTMITITSALYTTKETIPEETASSTAHL
WEKKDTKTLKMWFLEESNETEKIAPTTELVPKG
EMIKMNIDSIFIVLEAGIGHRTVPMLLAKSRFS
GEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLL
EPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDP
EEENYKVPEYKTVISFHSKDQLNITLSKCGLVM
LNNLVKAFTEAATGSSADFVKDLAPFMILNSLGL
TISVSPSDSFSVLNIPMAKSYVLKNGESLSMDY
IRTKDNDHFNAMTSLSSKLFFILLTPVNHSTAD
KIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEG
SKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTAS
PENEFNIPLGSYRSFIFLKPEDENYQMCEGIDF
EEIIKNDGALLKKKCRSKNPSKESFLINIVPEKD
NLTSLSVYSEDGWDLPYIMHLWPPILLRNLLPY
KIAYYIEGIENSVFTLSEGHSAQICTAQLGKAR
LHLKLLDYLNHDWKSEYHIKPNQQDISFVSFTCV
TEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVN
KTGRMLQYKADGIHRKHPPNYKKPVLFSFQPNH
FFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCK
GLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKN
KSKYHISVAEEGNDKWLSLDLEQCIPFWPEYAS
SKLLIQVERSEDPPKRIYFNKQENCILLRLDNEL
GGIIAEVNLAEHSTVITFLDYHDGAATFLLINH
TKNELVQYNQSSLSEIEDSLPPGKAVFYTWADP
VGSRRLKWRCRKSHGEVTQKDDMMMPIDLGEKTI
YLVSFFEGLQRIILFTEDPRVFKVTYESEKAEL
AEQEIAVALQDVGISLVNNYTKQEVAYIGITSS
DVVWETKPKKKARWKPMSVKHTEKLEREFKEYTE
SSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHV
IALRRNYLPALKVEYNTSAHQSSFRIQIYRIQI
QNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDV
SIVMRSAGHSQISRIKYFKVLIQEMDLRLDLGF
IYALTDLMTEAEVTENTEVELFHKDIEAFKEEY
KTASLVDQSQVSLYEYFHISPIKLHLSVSLSSGR
EEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQ
DVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQA
IKQMYVLILGLDVLGNPFGLIREFSEGVEAFFYE
PYQGAIQGPEEFVEGMALGLKALVGGAVGGLAG
AASKITGAMAKGVAAMTMDEDYQQKRREAMNKQ
PAGFREGITRGGKGLVSGFVSGITGIVTKPIKGA
QKGGAAGFFKGVGKGLVGAVARPTGGIIDMASS
TFQGIKRATETSEVESLRPPRFFNEDGVIRPYR
LRDGTGNQMLQVMENGRFAKYKYFTHVMINKTDM
LMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKE
PFIVHGRRLRIEAKERVKSVFHAREFGKIINFK
TPEDARWILTKLQEAREPSPSL*QRTLPEDTQQ*
VITAPRLPSKTCLGSILQK*FQVPCILDAKKQK
QTKKQKQKNKTRIR*NSYVIKIF*FFSNYPVF*
IESCIYL*F*LFCKRRQNYES*VFAPSFSL*WWR
GCP*FISTWSQV*CF*FTFCTSVMLISNSLSDG
*EIKHCLSGIKRTLVVVSSES*SSFAR*IF*YY
FPF*YKG*V*IVLKMHSIIKNNLLKYNL*HRLKP
PLKKP*RNKYPTQKRKSVSEL*GL*NISSSLFH
EIYLVYPSHVFNRLLISKENF*SLNNAYFPFTV
NME*TQFPTS*IVYYASNRQSLSYKVYVP*NLTQ
*PVPLPID*EFLVCLLYSYSNESHAFKFTAHHR
NHQLYISKNKDMRFSFLVFVQDLCTLILMDCFR
*KRMNV*L*TVKRMMQDPI*LLNNTEYSMHVVCA
TKLLLTVFGIEDSV*SIVVKFFSGSLNPRFVVK
AKINSMLYCNCISC*PNLLNAIDFSLITKTHCL
FSVVSPKMLFSLLNL
Sequence NM_015186
TTCCTCCCTCTCAGGGCTGCGCGCCCAGGTCTGCGCCGCGCTCCGCCTCCAGCCGCGCGCAGACTTGCGCACGCGTCGTGAGAGCGACCGCCTCCGTCTCTCGCTGGGCTCGCTAGGGCTGCGCGTTGGGCCAGCGGGGGCGCCGCAGCTGAAGCCGCCCCGGAGCCGGTGAACCGAATTACCTCGAGGGAGGGGCGTGG
GGAAGGCGGCGGGAGGAGGAGCGCACGGGCCGGCTGCCGTGCCCACCACGGCTGAGGAACATGGTTTTCGAGTCGGTGGTCGTGGACGTGTTGAACCGGT
TCTTGGGGGACTATGTGGTGGACTTGGACACGTCCCAGCTCTCTCTGGGCATCTGGAAAGGAGCTGTGGCCCTCAAGAATCTTCAAATTAAAGAAAATGC
CCTGAGTCAACTGGATGTACCATTTAAAGTTAAAGTTGGTCACATAGGTAATCTTAAACTTATAATTCCATGGAAAAACCTTTATACTCAACCTGTTGAA
GCCGTATTGGAAGAAATTTATTTACTTATAGTGCCTTCTTCTAGAATAAAATATGATCCTTTAAAAGAAGAGAAACAACTCATGGAAGCAAAGCAACAGG
AACTGAAAAGAATAGAAGAAGCAAAACAAAAAGTAGTTGATCAAGAACAACATCTGCCGGAAAAACAGGACACTTTTGCAGAAAAATTAGTTACACAGAT
CATAAAAAATCTTCAGGTGAAAATTTCCAGTATCCATATTCGTTATGAAGATGATATCACAAATCGGGACAAACCGCTGTCATTTGGTATTTCCCTTCAA
AATCTGAGCATGCAGACAACTGATCAATACTGGGTTCCATGTTTACATGATGAAACTGAGAAACTGGTTCGTAAGTTAATCCGATTGGATAACCTGTTTG
CCTATTGGAATGTGAAGTCTCAGATGTTTTATCTTAGTGATTATGATAACTCCTTGGACGACTTGAAGAATGGCATTGTCAATGAAAATATTGTTCCAGA
AGGTTATGATTTTGTATTTCGTCCCATATCTGCTAATGCCAAACTTGTGATGAATCGCCGATCTGATTTTGACTTTTCTGCCCCCAAAATAAACTTGGAA
ATTGAGTTACATAACATAGCAATTGAATTTAATAAACCACAGTATTTCAGTATTATGGAGCTTCTTGAATCAGTTGATATGATGGCACAAAATCTGCCAT
ATAGGAAGTTCAAACCTGATGTGCCTCTTCACCACCATGCCAGAGAATGGTGGGCTTATGCTATACATGGCGTTCTTGAAGTAAATGTTTGCCCCAGGTT
ATGGATGTGGTCATGGAAGCATATTAGAAAACATAGGCAAAAAGTGAAGCAATATAAAGAACTGTATAAAAAAAAGTTAACAAGTAAGAAGCCACCTGGT
GAACTTCTCGTGTCTTTGGAGGAGTTGGAAAAAACCTTGGATGTCTTTAATATAACTATAGCTAGACAGACGGCAGAAGTTGAGGTAAAGAAAGCTGGAT
ACAAAATTTACAAAGAAGGAGTAAAAGATCCAGAGGATAATAAAGGGTGGTTTAGCTGGCTATGGTCTTGGTCAGAACAAAATACTAATGAACAGCAACC
AGATGTTCAACCTGAAACTCTTGAAGAAATGTTGACACCTGAAGAAAAAGCTTTACTCTATGAAGCAATTGGCTATAGTGAAACAGCAGTTGATCCAACT
TTACTAAAAACATTTGAAGCCTTGAAGTTTTTTGTCCACTTGAAAAGTATGTCTATTGTTCTAAGAGAAAATCATCAAAAACCTGAGCTGGTAGATATTG
TAATAGAAGAATTTAGCACCTTAATTGTGCAAAGACCAGGAGCACAAGCAATAAAATTTGAAACTAAAATAGATTCATTTCATATTACTGGCTTACCAGA
TAATTCAGAAAAACCCCGCCTCCTGTCTTCATTGGATGATGCAATGTCACTTTTCCAAATTACATTTGAGATAAATCCATTAGATGAAACTGTTTCTCAG
AGGTGTATCATAGAAGCTGAACCTTTAGAAATCATATATGATGCAAGGACAGTGAATAGTATAGTGGAATTCTTCAGACCTCCAAAAGAGGTACATCTAG
CACAGCTCACTGCAGCAACTTTGACAAAACTGGAAGAATTTCGCAGTAAGACAGCAACAGGTCTACTGTATATTATTGAAACACAGAAAGTTCTTGATCT
CAAAATTAATTTGAAGGCTTCATATATTATTGTCCCACAAGATGGAATTTTTAGTCCTACATCAAATCTGCTTCTTTTGGACCTTGGTCATCTAAAGGTG
ACGAGTAAAAGTCGTTCTGAATTACCAGATGTGAAACAAGGTGAGGCCAATCTTAAAGAGATAATGGATAGAGCTTATGATTCATTTGATATTCAACTTA
CAAGTGTACAGCTGCTTTACAGTAGAGTTGGTGATAATTGGAGAGAAGCACGAAAACTCAGTGTATCTACCCAGCATATTTTGGTACCCATGCACTTCAA
TTTGGAACTGTCTAAGGCCATGGTTTTCATGGATGTAAGGATGCCCAAATTCAAGATTTATGGAAAGTTACCTCTTATTTCTTTACGAATCTCAGATAAA
AAACTACAAGGGATTATGGAATTGATTGAAAGCATTCCAAAACCTGAACCAGTAACTGAAGTATCTGCCCCTGTCAAATCATTCCAGATTCAAACATCTA
CTTCTTTGGGAACATCACAGATTTCACAGAAAATAATTCCTCTCTTGGAACTTCCATCTGTTTCTGAAGATGATTCAGAGGAGGAATTTTTTGATGCACC
ATGTAGTCCCTTGGAAGAACCTCTTCAGTTTCCAACTGGAGTTAAAAGTATTCGAACCAGAAAGTTACAAAAGCAGGATTGTTCAGTAAATATGACTACA
TTTAAAATAAGATTTGAAGTACCAAAGGTTTTGATCGAGTTTTATCACCTTGTTGGAGATTGTGAACTATCTGTGGTAGAAATTCTTGTTTTAGGATTGG
GTGCAGAAATTGAGATTAGAACATACGATTTGAAAGCAAATGCCTTTTTGAAAGAGTTCTGCTTAAAATGCCCAGAATACTTGGATGAAAACAAGAAACC
AGTTTATTTGGTTACAACCCTGGATAACACAATGGAAGACCTGTTAACGCTGGAATATGTAAAGGCTGAAAAGAATGTACCCGACTTGAAAAGTACCTAT
AACAATGTTTTACAATTGATTAAGGTAAATTTTTCCTCTTTGGATATTCATTTACACACTGAAGCACTTCTGAATACAATAAATTATCTTCATAATATCC
TTCCGCAATCAGAGGAAAAATCAGCCCCAGTGTCCACTACAGAGACTGAAGACAAAGGAGATGTCATTAAAAAATTAGCTTTAAAACTATCCACAAATGA
AGATATCATTACTTTGCAGATTTTAGCAGAATTATCGTGTTTACAGATCTTTATTCAAGATCAGAAATGTAACATTTCTGAAATTAAGATTGAAGGGCTT
GATTCTGAGATGATTATGAGGCCTTCAGAAACTGAAATAAACGCAAAGCTAAGGAATATAATTGTTTTAGATTCTGATATAACAGCTATATACAAAAAGG
CTGTTTATATCACTGGAAAAGAAGTTTTCAGCTTCAAAATGGTTTCTTACATGGATGCAACTGCTGGTTCTGCATACACAGATATGAATGTGGTTGACAT
TCAGGTTAATTTAATAGTTGGTTGCATTGAAGTAGTTTTTGTCACGAAATTTCTATATTCTATATTGGCTTTTATAGATAATTTTCAGGCAGCTAAACAA
GCCTTGGCTGAGGCAACTGTTCAGGCAGCTGGAATGGCTGCTACTGGTGTAAAAGAACTCGCACAAAGGAGTTCCAGAATGGCACTGGATATTAACATCA
AAGCCCCAGTTGTGGTCATCCCGCAGTCTCCAGTTTCTGAAAATGTTTTTGTTGCTGATTTTGGACTAATTACAATGACAAATACCTTTCATATGATAAC
AGAGAGCCAGAGCTCTCCCCCACCTGTTATTGATTTGATAACAATAAAGCTGAGTGAAATGCGACTATACAGATCTCGATTTATTAATGATGCATACCAG
GAAGTACTGGATCTACTCCTGCCATTAAATCTTGAGGTTGTGGTTGAACGAAATTTATGCTGGGAGTGGTACCAGGAAGTTCCTTGTTTTAATGTAAATG
CTCAGCTGAAACCAATGGAGTTCATTCTTAGTCAAGAAGATATAACAACTATTTTTAAAACATTGCATGGCAATATATGGTATGAAAAAGATGGTAGTGC
CTCACCTGCTGTAACAAAAGACCAATACAGTGCCACTAGTGGAGTTACTACTAATGCTTCACACCATTCAGGAGGAGCAACTGTGGTGACAGCTGCTGTG
GTAGAAGTACATTCACGTGCCTTACTAGTTAAGACAACACTAAACATAAGCTTCAAAACTGATGATCTCACCATGGTGCTGTATAGTCCAGGTCCTAAAC
AGGCTTCCTTTACAGATGTTCGTGATCCTTCTCTGAAACTTGCTGAATTTAAATTGGAGAATATTATAAGTACTTTAAAAATGTATACAGATGGCTCAAC
ATTTTCTTCCTTCTCATTAAAAAACTGTATTTTAGATGATAAAAGACCTCATGTCAAGAAAGCAACTCCTCGAATGATAGGACTGACAGTTGGTTTTGAC
AAAAAAGACATGATGGATATAAAGTACAGGAAAGTCAGAGATGGTTGTGTGACTGATGCGGTCTTTCAAGAAATGTATATTTGTGCAAGCGTAGAATTTC
TGCAGACTGTTGCAAATGTCTTTCTTGAGGCCTACACCACAGGCACTGCTGTAGAAACCAGTGTGCAAACATGGACTGCTAAGGAAGAAGTACCTACACA
GGAATCAGTGAAGTGGGAAATTAATGTTATTATTAAAAATCCTGAAATTGTGTTTGTAGCTGACATGACAAAAAATGATGCTCCTGCTTTAGTCATTACA
ACACAATGTGAAATTTGCTATAAAGGTAACCTTGAAAATAGTACAATGACTGCTGCCATTAAAGATCTCCAAGTGAGAGCCTGCCCGTTTCTTCCAGTCA
AGAGAAAAGGCAAAATCACTACTGTTTTGCAGCCCTGTGACTTGTTTTATCAAACTACTCAGAAAGGTACAGATCCACAAGTGATCGATATGTCAGTAAA
ATCCCTGACACTAAAGGTTTCACCAGTTATTATAAATACTATGATTACCATAACTTCAGCACTGTATACAACTAAGGAAACCATCCCAGAAGAAACGGCT
TCTTCTACTGCACATTTATGGGAAAAGAAGGATACAAAGACTTTAAAAATGTGGTTTCTTGAAGAATCAAATGAAACTGAAAAAATAGCTCCCACAACTG
AATTGGTACCCAAAGGCGAGATGATAAAAATGAACATTGATTCTATTTTTATAGTTCTTGAGGCTGGAATTGGTCATAGAACAGTACCTATGCTTCTGGC
AAAGTCACGTTTTTCAGGGGAAGGCAAAAACTGGAGTTCCCTAATAAATCTGCACTGTCAGCTTGAGCTAGAAGTGCATTATTATAATGAAATGTTTGGT
GTATGGGAGCCTTTGCTTGAACCCTTAGAAATTGATCAGACTGAGGATTTTAGACCATGGAATCTTGGTATCAAGATGAAAAAGAAAGCAAAAATGGCCA
TTGTTGAGTCAGATCCTGAAGAAGAAAACTACAAAGTGCCAGAATATAAAACTGTCATCAGTTTCCATTCAAAAGACCAATTAAACATTACATTATCCAA
ATGTGGTCTTGTAATGTTAAACAATTTAGTCAAGGCATTTACAGAAGCTGCCACTGGATCTTCAGCTGACTTCGTAAAGGATCTAGCACCATTTATGATT
TTAAATTCCCTTGGACTTACTATTTCTGTTTCGCCAAGTGATTCTTTTAGTGTACTCAACATTCCTATGGCAAAATCATATGTATTGAAAAATGGAGAAA
GTTTAAGTATGGATTATATCCGAACCAAGGACAATGATCATTTCAATGCAATGACCAGCCTAAGCAGCAAACTCTTCTTCATTCTTCTTACACCTGTTAA
CCATTCTACTGCTGATAAGATTCCTTTAACAAAAGTGGGACGACGTCTGTACACTGTAAGACACAGAGAGTCTGGCGTTGAAAGATCTATTGTTTGTCAA
ATTGATACAGTAGAAGGAAGTAAGAAGGTCACAATTCGCTCCCCAGTGCAGATAAGAAATCATTTTTCAGTCCCACTGTCTGTTTACGAAGGGGATACCT
TATTGGGAACTGCCTCACCTGAAAATGAATTCAACATACCATTAGGATCTTACCGATCATTCATTTTTCTGAAGCCAGAAGATGAGAACTATCAAATGTG
TGAAGGAATTGACTTTGAAGAGATTATAAAAAATGATGGTGCTCTTCTAAAGAAGAAATGTAGATCTAAAAACCCTTCTAAGGAATCATTTCTCATTAAT
ATTGTTCCAGAAAAAGATAATTTAACATCTCTATCAGTGTATTCAGAAGATGGTTGGGATTTACCATACATAATGCATTTGTGGCCACCTATCCTGCTCC
GAAATCTTCTTCCTTACAAAATTGCTTATTATATAGAGGGAATTGAAAATTCGGTTTTTACTCTAAGTGAAGGACATTCAGCCCAGATTTGTACTGCACA
GTTGGGTAAAGCCAGGCTACATTTAAAATTACTTGACTATCTCAATCACGATTGGAAAAGTGAATATCACATAAAGCCTAATCAGCAAGACATTAGTTTT
GTCAGTTTTACTTGTGTTACAGAAATGGAAAAGACTGATTTAGATATTGCTGTCCATATGACTTACAATACTGGTCAGACAGTTGTGGCATTTCATAGTC
CTTATTGGATGGTCAATAAAACTGGCCGCATGTTACAGTACAAAGCAGACGGAATTCATCGAAAGCATCCACCTAATTATAAAAAGCCAGTTCTCTTTTC
TTTTCAGCCAAATCACTTTTTTAATAACAATAAGGTTCAACTTATGGTAACTGATAGTGAGTTGTCCAATCAGTTTTCAATTGATACTGTTGGTAGTCAT
GGAGCTGTTAAATGTAAAGGCCTGAAAATGGACTATCAAGTTGGTGTCACTATAGACCTGAGCAGTTTTAACATTACTAGAATTGTGACATTTACCCCTT
TTTATATGATTAAAAACAAAAGCAAATACCATATATCAGTGGCTGAAGAAGGAAATGATAAATGGCTCTCTCTTGATTTGGAGCAGTGTATCCCCTTTTG
GCCTGAGTATGCTTCTAGTAAACTTCTTATTCAAGTCGAAAGGAGTGAAGATCCTCCCAAAAGGATATATTTTAACAAGCAGGAAAATTGTATTCTATTG
CGTCTAGATAACGAGCTTGGAGGTATTATAGCAGAAGTGAATTTGGCCGAGCATTCTACAGTTATTACATTTTTAGATTATCATGATGGAGCAGCTACAT
TCCTCTTAATAAATCACACAAAGAATGAACTTGTTCAATACAATCAAAGTTCTCTCAGTGAAATAGAAGATTCCCTCCCTCCTGGTAAAGCCGTGTTTTA
TACATGGGCTGATCCGGTGGGCTCTAGAAGGCTGAAGTGGAGATGTAGAAAAAGCCATGGTGAAGTAACACAGAAGGATGATATGATGATGCCTATAGAT
TTGGGGGAAAAGACAATATATTTAGTTTCATTCTTTGAAGGTTTACAACGCATTATTTTATTCACTGAAGATCCAAGGGTATTTAAAGTAACATATGAAA
GTGAGAAAGCAGAGTTAGCAGAGCAAGAAATTGCAGTGGCATTACAAGATGTTGGAATTTCTCTTGTCAACAATTACACGAAGCAAGAAGTAGCCTATAT
AGGCATTACAAGTTCTGATGTGGTTTGGGAAACAAAGCCCAAGAAGAAGGCAAGATGGAAGCCAATGAGTGTAAAGCACACTGAGAAGTTAGAGAGAGAA
TTTAAGGAATATACTGAATCTTCTCCTTCAGAAGATAAGGTTATTCAGTTGGACACTAATGTTCCGGTTCGCCTAACCCCTACTGGTCATAACATGAAAA
TTCTGCAGCCGCATGTAATAGCTCTACGAAGAAATTATCTTCCAGCATTAAAAGTGGAATATAACACATCTGCACATCAATCATCATTTAGAATTCAGAT
TTACAGAATACAGATCCAAAATCAGATACATGGTGCTGTATTTCCCTTTGTGTTTTATCCTGTTAAACCTCCAAAGTCGGTCACCATGGATTCAGCACCA
AAGCCCTTTACAGATGTCAGTATTGTCATGAGATCTGCAGGACATTCCCAGATATCACGTATTAAGTATTTCAAAGTATTGATTCAAGAAATGGATCTCA
GGTTAGATCTTGGGTTTATCTATGCTTTAACAGACCTTATGACAGAAGCTGAGGTGACTGAAAATACAGAGGTTGAGCTTTTTCATAAAGATATAGAAGC
TTTCAAAGAAGAATATAAAACAGCCTCATTAGTAGATCAATCACAAGTCAGCCTCTATGAATATTTTCATATATCTCCTATCAAGTTACATTTAAGTGTT
TCACTGAGTTCCGGCAGAGAAGAAGCTAAAGATTCAAAACAAAATGGAGGACTGATTCCAGTTCATTCTTTAAATCTTTTGCTGAAGAGTATTGGTGCCA
CACTGACAGATGTACAAGATGTAGTTTTTAAGCTTGCATTTTTTGAACTCAACTATCAGTTCCATACAACATCCGATCTACAGTCTGAAGTCATAAGACA
CTATTCAAAACAGGCCATTAAGCAGATGTATGTACTCATTCTTGGACTTGATGTTTTGGGAAATCCATTTGGCTTAATTAGAGAATTTTCTGAAGGTGTA
GAAGCATTTTTTTATGAACCTTACCAGGGAGCCATCCAGGGTCCTGAAGAGTTTGTGGAAGGAATGGCACTAGGACTTAAGGCACTAGTTGGTGGAGCTG
TTGGTGGATTGGCTGGTGCTGCCTCCAAAATCACCGGTGCTATGGCTAAGGGGGTAGCAGCTATGACCATGGATGAAGACTACCAACAGAAGAGAAGAGA
AGCCATGAATAAGCAACCAGCTGGTTTTAGAGAAGGCATCACTCGTGGAGGAAAAGGCTTAGTTTCTGGATTTGTTAGTGGCATAACAGGAATTGTTACA
AAACCAATCAAAGGAGCTCAAAAAGGAGGAGCAGCTGGTTTCTTTAAAGGTGTTGGGAAAGGTTTAGTAGGAGCGGTAGCAAGGCCAACTGGAGGCATCA
TAGACATGGCTAGCAGTACATTTCAGGGAATAAAAAGAGCTACAGAGACTTCTGAAGTGGAGAGTCTGCGACCTCCTCGGTTCTTCAATGAAGATGGAGT
TATCAGACCGTACAGGTTGAGGGATGGGACTGGAAATCAAATGTTACAGAAAATTCAATTCTACAGGGAGTGGATTATGACTCACAGTAGCAGTAGTGAT
GATGATGATGATGATGATGATGATGATGAGTCAGATCTAAACCATTAAAATTCATATGTTCTTTATTTTACTTGGAATGTTTCATTAACATGTTTTGTAT
GACTTATACCATAATGCCCATATGTCCATTTATAGGGAGGTAAAACACATTTTCTTTTAAAATGTTTTCCTACACATTTTCATAAAGCAAAATAATTGTA
TTATTTAAGCACAGAAAAAAATGTATCTTACATCCAAAGTAGGGAGGGCATCCAACATATTATAGATTTGCTTTTATATATTTTATAGCTTTGTATTGCA
TAGTTTGTCTTTAAGAGTTCAAGTTAGACTTAAATATAATTTTGATGTTCACTGGTTTTATTTTAAATTGCCTTCTTATTTGTTAGCAAAATGCCTTTTT
TTAATGGTCTCTGTAAATTTTCTGGGCTTTAATGTAATGCCACTGTGTAAAAAAAAAGGAAGAAAATAGTAATAGCCATTTAATGTTTTATATTTATCAT
TTTAAAGATATTTTTGTCAAATTTCTTTTAATAATAATAAACATATGTAATC
- refseq_VPS13A.F1 (forward primer)
- refseq_VPS13A.R1 (reverse primer)
- Single exon skipping
Frame 0
FLPLRAARPGLRRAPPPAARRLAHAS*ERPPPSLAGLARAARWASGGAAAEAAPEPVNRITSREGRG
EGGGRRSARAGCRAHHG*GTWFSSRWSWTC*TG
SWGTMWWTWTRPSSLWASGKELWPSRIFKLKKM
P*VNWMYHLKLKLVT*VILNL*FHGKTFILNLLK
PYWKKFIYL*CLLLE*NMIL*KKRNNSWKQSNR
N*KE*KKQNKK*LIKNNICRKNRTLLQKN*LHR
S*KIFR*KFPVSIFVMKMISQIGTNRCHLVFPFK
I*ACRQLINTGFHVYMMKLRNWFVS*SDWITCL
PIGM*SLRCFILVIMITPWTT*RMALSMKILFQ
KVMILYFVPYLLMPNL**IADLILTFLPPK*TWK
LSYIT*QLNLINHSISVLWSFLNQLI*WHKICH
IGSSNLMCLFTTMPENGGLMLYMAFLK*MFAPG
YGCGHGSILENIGKK*SNIKNCIKKS*QVRSHLV
NFSCLWRSWKKPWMSLI*L*LDRRQKLR*RKLD
TKFTKKE*KIQRIIKGGLAGYGLGQNKILMNSN
QMFNLKLLKKC*HLKKKLYSMKQLAIVKQQLIQL
Y*KHLKP*SFLST*KVCLLF*EKIIKNLSW*IL
**KNLAP*LCKDQEHKQ*NLKLK*IHFILLAYQ
IIQKNPASCLHWMMQCHFSKLHLR*IH*MKLFLR
GVS*KLNL*KSYMMQGQ*IV*WNSSDLQKRYI*
HSSLQQL*QNWKNFAVRQQQVYCILLKHRKFLI
SKLI*RLHILLSHKMEFLVLHQICFFWTLVI*R*
RVKVVLNYQM*NKVRPILKR*WIELMIHLIFNL
QVYSCFTVELVIIGEKHENSVYLPSIFWYPCTS
IWNCLRPWFSWM*GCPNSRFMESYLLFLYESQIK
NYKGLWN*LKAFQNLNQ*LKYLPLSNHSRFKHL
LLWEHHRFHRK*FLSWNFHLFLKMIQRRNFLMH
HVVPWKNLFSFQLELKVFEPESYKSRIVQ*I*LH
LK*DLKYQRF*SSFITLLEIVNYLW*KFLF*DW
VQKLRLEHTI*KQMPF*KSSA*NAQNTWMKTRN
QFIWLQPWITQWKTC*RWNM*RLKRMYPT*KVPI
TMFYN*LR*IFPLWIFIYTLKHF*IQ*IIFIIS
FRNQRKNQPQCPLQRLKTKEMSLKN*L*NYPQM
KISLLCRF*QNYRVYRSLFKIRNVTFLKLRLKGL
ILR*L*GLQKLK*TQS*GI*LF*ILI*QLYTKR
LFISLEKKFSASKWFLTWMQLLVLHTQI*MWLT
FRLI**LVALK*FLSRNFYILYWLL*IIFRQLNK
PWLRQLFRQLEWLLLV*KNSHKGVPEWHWILTS
KPQLWSSRSLQFLKMFLLLILD*LQ*QIPFI**
QRARALPHLLLI**Q*S*VKCDYTDLDLLMMHTR
KYWIYSCH*ILRLWLNEIYAGSGTRKFLVLM*M
LS*NQWSSFLVKKI*QLFLKHCMAIYGMKKMVV
PHLL*QKTNTVPLVELLLMLHTIQEEQLW*QLLW
*KYIHVPY*LRQH*T*ASKLMISPWCCIVQVLN
RLPLQMFVILL*NLLNLNWRIL*VL*KCIQMAQ
HFLPSH*KTVF*MIKDLMSRKQLLE**D*QLVLT
KKT*WI*STGKSEMVV*LMRSFKKCIFVQA*NF
CRLLQMSFLRPTPQALL*KPVCKHGLLRKKYLH
RNQ*SGKLMLLLKILKLCL*LT*QKMMLLL*SLQ
HNVKFAIKVTLKIVQ*LLPLKISK*EPARFFQS
REKAKSLLFCSPVTCFIKLLRKVQIHK*SICQ*
NP*H*RFHQLL*IL*LP*LQHCIQLRKPSQKKRL
LLLHIYGKRRIQRL*KCGFLKNQMKLKK*LPQL
NWYPKAR**K*TLILFL*FLRLELVIEQYLCFW
QSHVFQGKAKTGVP**ICTVSLS*KCIIIMKCLV
YGSLCLNP*KLIRLRILDHGILVSR*KRKQKWP
LLSQILKKKTTKCQNIKLSSVSIQKTN*TLHYP
NVVL*C*TI*SRHLQKLPLDLQLTS*RI*HHL*F
*IPLDLLFLFRQVILLVYSTFLWQNHMY*KMEK
V*VWIISEPRTMIISMQ*PA*AANSSSFFLHLL
TILLLIRFL*QKWDDVCTL*DTESLALKDLLFVK
LIQ*KEVRRSQFAPQCR*EIIFQSHCLFTKGIP
YWELPHLKMNSTYH*DLTDHSFF*SQKMRTIKC
VKELTLKRL*KMMVLF*RRNVDLKTLLRNHFSLI
LFQKKII*HLYQCIQKMVGIYHT*CICGHLSCS
EIFFLTKLLII*RELKIRFLL*VKDIQPRFVLH
SWVKPGYI*NYLTISITIGKVNIT*SLISKTLVL
SVLLVLQKWKRLI*ILLSI*LTILVRQLWHFIV
LIGWSIKLAACYSTKQTEFIESIHLIIKSQFSF
LFSQITFLITIRFNLW*LIVSCPISFQLILLVVM
ELLNVKA*KWTIKLVSL*T*AVLTLLEL*HLPL
FI*LKTKANTIYQWLKKEMINGSLLIWSSVSPF
GLSMLLVNFLFKSKGVKILPKGYILTSRKIVFYC
V*ITSLEVL*QK*IWPSILQLLHF*IIMMEQLH
SS**ITQRMNLFNTIKVLSVK*KIPSLLVKPCF
IHGLIRWALEG*SGDVEKAMVK*HRRMI**CL*I
WGKRQYI*FHSLKVYNALFYSLKIQGYLK*HMK
VRKQS*QSKKLQWHYKMLEFLLSTITRSKK*PI
*ALQVLMWFGKQSPRRRQDGSQ*V*STLRS*REN
LRNILNLLLQKIRLFSWTLMFRFA*PLLVIT*K
FCSRM**LYEEIIFQH*KWNITHLHINHHLEFR
FTEYRSKIRYMVLYFPLCFILLNLQSRSPWIQHQ
SPLQMSVLS*DLQDIPRYHVLSISKY*FKKWIS
G*ILGLSML*QTL*QKLR*LKIQRLSFFIKI*K
LSKKNIKQPH**INHKSASMNIFIYLLSSYI*VF
H*VPAEKKLKIQNKMED*FQFIL*IFC*RVLVP
H*QMYKM*FLSLHFLNSTISSIQHPIYSLKS*D
TIQNRPLSRCMYSFLDLMFWEIHLA*LENFLKV*
KHFFMNLTREPSRVLKSLWKEWH*DLRH*LVEL
LVDWLVLPPKSPVLWLRG*QL*PWMKTTNRREE
KP*ISNQLVLEKASLVEEKA*FLDLLVA*QELLQ
NQSKELKKEEQLVSLKVLGKV**ER*QGQLEAS
*TWLAVHFRE*KELQRLLKWRVCDLLGSSMKME
LSDRTG*GMGLEIKCYRKFNSTGSGL*LTVAVVM
MMMMMMMMMSQI*TIKIHMFFILLGMFH*HVLY
DLYHNAHMSIYREVKHIFF*NVFLHIFIKQNNC
II*AQKKMYLTSKVGRASNIL*ICFYIFYSFVLH
SLSLRVQVRLKYNFDVHWFYFKLPSYLLAKCLF
LMVSVNFLGFNVMPLCKKKGRK***PFNVLYLS
F*RYFCQISFNNNKHM*
Frame 1
SSLSGLRAQVCAALRLQPRADLRTRRESDRLRLSLGSLGLRVGPAGAPQLKPPRSR*TELPRGRGV
GKAAGGGAHGPAAVPTTAEEHGFRVGGRGRVEPV
LGGLCGGLGHVPALSGHLERSCGPQESSN*RKC
PESTGCTI*S*SWSHR*S*TYNSMEKPLYSTC*
SRIGRNLFTYSAFF*NKI*SFKRRETTHGSKATG
TEKNRRSKTKSS*SRTTSAGKTGHFCRKISYTD
HKKSSGENFQYPYSL*R*YHKSGQTAVIWYFPS
KSEHADN*SILGSMFT**N*ETGS*VNPIG*PVC
LLECEVSDVLS**L**LLGRLEEWHCQ*KYCSR
RL*FCISSHIC*CQTCDESPI*F*LFCPQNKLG
N*VT*HSN*I**TTVFQYYGAS*IS*YDGTKSAI
*EVQT*CASSPPCQRMVGLCYTWRS*SKCLPQV
MDVVMEAY*KT*AKSEAI*RTV*KKVNK*EATW
*TSRVFGGVGKNLGCL*YNYS*TDGRS*GKESWI
QNLQRRSKRSRG**RVV*LAMVLVRTKY**TAT
RCST*NS*RNVDT*RKSFTL*SNWL**NSS*SN
FTKNI*SLEVFCPLEKYVYCSKRKSSKT*AGRYC
NRRI*HLNCAKTRSTSNKI*N*NRFISYYWLTR
*FRKTPPPVFIG*CNVTFPNYI*DKSIR*NCFS
EVYHRS*TFRNHI*CKDSE*YSGILQTSKRGTSS
TAHCSNFDKTGRISQ*DSNRSTVYY*NTESS*S
QN*FEGFIYYCPTRWNF*SYIKSASFGPWSSKG
DE*KSF*ITRCETR*GQS*RDNG*SL*FI*YSTY
KCTAALQ*SW**LERSTKTQCIYPAYFGTHALQ
FGTV*GHGFHGCKDAQIQDLWKVTSYFFTNLR*
KTTRDYGID*KHSKT*TSN*SICPCQIIPDSNIY
FFGNITDFTENNSSLGTSICF*R*FRGGIF*CT
M*SLGRTSSVSNWS*KYSNQKVTKAGLFSKYDY
I*NKI*STKGFDRVLSPCWRL*TICGRNSCFRIG
CRN*D*NIRFESKCLFERVLLKMPRILG*KQET
SLFGYNPG*HNGRPVNAGICKG*KECTRLEKYL
*QCFTID*GKFFLFGYSFTH*STSEYNKLSS*YP
SAIRGKISPSVHYRD*RQRRCH*KISFKTIHK*
RYHYFADFSRIIVFTDLYSRSEM*HF*N*D*RA
*F*DDYEAFRN*NKRKAKEYNCFRF*YNSYIQKG
CLYHWKRSFQLQNGFLHGCNCWFCIHRYECG*H
SG*FNSWLH*SSFCHEISIFYIGFYR*FSGS*T
SLG*GNCSGSWNGCYWCKRTRTKEFQNGTGY*HQ
SPSCGHPAVSSF*KCFCC*FWTNYNDKYLSYDN
REPELSPTCY*FDNNKAE*NATIQISIY**CIP
GSTGSTPAIKS*GCG*TKFMLGVVPGSSLF*CKC
SAETNGVHS*SRRYNNYF*NIAWQYMV*KRW*C
LTCCNKRPIQCH*WSYY*CFTPFRRSNCGDSCC
GRSTFTCLTS*DNTKHKLQN**SHHGAV*SRS*T
GFLYRCS*SFSETC*I*IGEYYKYFKNVYRWLN
IFFLLIKKLYFR**KTSCQESNSSNDRTDSWF*
QKRHDGYKVQESQRWLCD*CGLSRNVYLCKRRIS
ADCCKCLS*GLHHRHCCRNQCANMDC*GRSTYT
GISEVGN*CYY*KS*NCVCS*HDKK*CSCFSHY
NTM*NLL*R*P*K*YNDCCH*RSPSESLPVSSSQ
EKRQNHYCFAAL*LVLSNYSERYRSTSDRYVSK
IPDTKGFTSYYKYYDYHNFSTVYN*GNHPRRNG
FFYCTFMGKEGYKDFKNVVS*RIK*N*KNSSHN*
IGTQRRDDKNEH*FYFYSS*GWNWS*NSTYASG
KVTFFRGRQKLEFPNKSALSA*ARSALL**NVW
CMGAFA*TLRN*SD*GF*TMESWYQDEKESKNGH
C*VRS*RRKLQSARI*NCHQFPFKRPIKHYIIQ
MWSCNVKQFSQGIYRSCHWIFS*LRKGSSTIYD
FKFPWTYYFCFAK*FF*CTQHSYGKIICIEKWRK
FKYGLYPNQGQ*SFQCNDQPKQQTLLHSSYTC*
PFYC**DSFNKSGTTSVHCKTQRVWR*KIYCLS
N*YSRRK*EGHNSLPSADKKSFFSPTVCLRRGYL
IGNCLT*K*IQHTIRILPIIHFSEARR*ELSNV
*RN*L*RDYKK*WCSSKEEM*I*KPF*GIISH*
YCSRKR*FNISISVFRRWLGFTIHNAFVATYPAP
KSSSLQNCLLYRGN*KFGFYSK*RTFSPDLYCT
VG*SQATFKIT*LSQSRLEK*ISHKA*SARH*F
CQFYLCYRNGKD*FRYCCPYDLQYWSDSCGIS*S
LLDGQ*NWPHVTVQSRRNSSKAST*L*KASSLF
FSAKSLF**Q*GSTYGN***VVQSVFN*YCW*S
WSC*M*RPENGLSSWCHYRPEQF*HY*NCDIYPF
LYD*KQKQIPYISG*RRK**MALS*FGAVYPLL
A*VCF**TSYSSRKE*RSSQKDIF*QAGKLYSI
ASR*RAWRYYSRSEFGRAFYSYYIFRLS*WSSYI
PLNKSHKE*TCSIQSKFSQ*NRRFPPSW*SRVL
YMG*SGGL*KAEVEM*KKPW*SNTEG*YDDAYR
FGGKDNIFSFIL*RFTTHYFIH*RSKGI*SNI*K
*ESRVSRARNCSGITRCWNFSCQQLHEARSSLY
RHYKF*CGLGNKAQEEGKMEANECKAH*EVRER
I*GIY*IFSFRR*GYSVGH*CSGSPNPYWS*HEN
SAAACNSSTKKLSSSIKSGI*HICTSIII*NSD
LQNTDPKSDTWCCISLCVLSC*TSKVGHHGFST
KALYRCQYCHEICRTFPDITY*VFQSIDSRNGSQ
VRSWVYLCFNRPYDRS*GD*KYRG*AFS*RYRS
FQRRI*NSLISRSITSQPL*IFSYISYQVTFKC
FTEFRQRRS*RFKTKWRTDSSSFFKSFAEEYWCH
TDRCTRCSF*ACIF*TQLSVPYNIRSTV*SHKT
LFKTGH*ADVCTHSWT*CFGKSIWLN*RIF*RC
RSIFL*TLPGSHPGS*RVCGRNGTRT*GTSWWSC
WWIGWCCLQNHRCYG*GGSSYDHG*RLPTEEKR
SHE*ATSWF*RRHHSWRKRLSFWIC*WHNRNCY
KTNQRSSKRRSSWFL*RCWERFSRSGSKANWRHH
RHG*QYISGNKKSYRDF*SGESATSSVLQ*RWS
YQTVQVEGWDWKSNVTENSILQGVDYDSQ*Q**
**********VRSKPLKFICSLFYLECFINMFCM
TYTIMPICPFIGR*NTFSFKMFSYTFS*SKIIV
LFKHRKKCILHPK*GGHPTYYRFAFIYFIALYC
IVCL*EFKLDLNIILMFTGFILNCLLIC*QNAFF
*WSL*IFWALM*CHCVKKKEENSNSHLMFYIYH
FKDIFVKFLLIIINICN
Frame 2
PPSQGCAPRSAPRSASSRAQTCARVVRATASVSRWAR*GCALGQRGRRS*SRPGAGEPNYLEGGAW
GRRREEERTGRLPCPPRLRNMVFESVVVDVLNR
FLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENA
LSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVE
AVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQ
ELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQI
IKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ
NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLF
AYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPE
GYDFVFRPISANAKLVMNRRSDFDFSAPKINLE
IELHNIAIEFNKPQYFSIMELLESVDMMAQNLP
YRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRL
WMWSWKHIRKHRQKVKQYKELYKKKLTSKKPPG
ELLVSLEELEKTLDVFNITIARQTAEVEVKKAG
YKIYKEGVKDPEDNKGWFSWLWSWSEQNTNEQQP
DVQPETLEEMLTPEEKALLYEAIGYSETAVDPT
LLKTFEALKFFVHLKSMSIVLRENHQKPELVDI
VIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPD
NSEKPRLLSSLDDAMSLFQITFEINPLDETVSQ
RCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHL
AQLTAATLTKLEEFRSKTATGLLYIIETQKVLDL
KINLKASYIIVPQDGIFSPTSNLLLLDLGHLKV
TSKSRSELPDVKQGEANLKEIMDRAYDSFDIQL
TSVQLLYSRVGDNWREARKLSVSTQHILVPMHFN
LELSKAMVFMDVRMPKFKIYGKLPLISLRISDK
KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTS
TSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAP
CSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTT
FKIRFEVPKVLIEFYHLVGDCELSVVEILVLGL
GAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKP
VYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTY
NNVLQLIKVNFSSLDIHLHTEALLNTINYLHNI
LPQSEEKSAPVSTTETEDKGDVIKKLALKLSTNE
DIITLQILAELSCLQIFIQDQKCNISEIKIEGL
DSEMIMRPSETEINAKLRNIIVLDSDITAIYKK
AVYITGKEVFSFKMVSYMDATAGSAYTDMNVVDI
QVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQ
ALAEATVQAAGMAATGVKELAQRSSRMALDINI
KAPVVVIPQSPVSENVFVADFGLITMTNTFHMIT
ESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQ
EVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVN
AQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSA
SPAVTKDQYSATSGVTTNASHHSGGATVVTAAV
VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPK
QASFTDVRDPSLKLAEFKLENIISTLKMYTDGST
FSSFSLKNCILDDKRPHVKKATPRMIGLTVGFD
KKDMMDIKYRKVRDGCVTDAVFQEMYICASVEF
LQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQ
ESVKWEINVIIKNPEIVFVADMTKNDAPALVIT
TQCEICYKGNLENSTMTAAIKDLQVRACPFLPV
KRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK
SLTLKVSPVIINTMITITSALYTTKETIPEETA
SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTT
ELVPKGEMIKMNIDSIFIVLEAGIGHRTVPMLLA
KSRFSGEGKNWSSLINLHCQLELEVHYYNEMFG
VWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMA
IVESDPEEENYKVPEYKTVISFHSKDQLNITLSK
CGLVMLNNLVKAFTEAATGSSADFVKDLAPFMI
LNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGE
SLSMDYIRTKDNDHFNAMTSLSSKLFFILLTPVN
HSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ
IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDT
LLGTASPENEFNIPLGSYRSFIFLKPEDENYQMC
EGIDFEEIIKNDGALLKKKCRSKNPSKESFLIN
IVPEKDNLTSLSVYSEDGWDLPYIMHLWPPILL
RNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQ
LGKARLHLKLLDYLNHDWKSEYHIKPNQQDISF
VSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHS
PYWMVNKTGRMLQYKADGIHRKHPPNYKKPVLFS
FQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH
GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTP
FYMIKNKSKYHISVAEEGNDKWLSLDLEQCIPFW
PEYASSKLLIQVERSEDPPKRIYFNKQENCILL
RLDNELGGIIAEVNLAEHSTVITFLDYHDGAAT
FLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFY
TWADPVGSRRLKWRCRKSHGEVTQKDDMMMPID
LGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYE
SEKAELAEQEIAVALQDVGISLVNNYTKQEVAYI
GITSSDVVWETKPKKKARWKPMSVKHTEKLERE
FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMK
ILQPHVIALRRNYLPALKVEYNTSAHQSSFRIQI
YRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAP
KPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDL
RLDLGFIYALTDLMTEAEVTENTEVELFHKDIEA
FKEEYKTASLVDQSQVSLYEYFHISPIKLHLSV
SLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGA
TLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRH
YSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV
EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGA
VGGLAGAASKITGAMAKGVAAMTMDEDYQQKRRE
AMNKQPAGFREGITRGGKGLVSGFVSGITGIVT
KPIKGAQKGGAAGFFKGVGKGLVGAVARPTGGI
IDMASSTFQGIKRATETSEVESLRPPRFFNEDGV
IRPYRLRDGTGNQMLQKIQFYREWIMTHSSSSD
DDDDDDDDDESDLNH*NSYVLYFTWNVSLTCFV
*LIP*CPYVHL*GGKTHFLLKCFPTHFHKAK*LY
YLSTEKNVSYIQSREGIQHIIDLLLYIL*LCIA
*FVFKSSS*T*I*F*CSLVLF*IAFLFVSKMPF
FNGLCKFSGL*CNATV*KKRKKIVIAI*CFIFII
LKIFLSNFF****TYVI
Sequence NM_033305
TTCCTCCCTCTCAGGGCTGCGCGCCCAGGTCTGCGCCGCGCTCCGCCTCCAGCCGCGCGCAGACTTGCGCACGCGTCGTGAGAGCGACCGCCTCCGTCTCTCGCTGGGCTCGCTAGGGCTGCGCGTTGGGCCAGCGGGGGCGCCGCAGCTGAAGCCGCCCCGGAGCCGGTGAACCGAATTACCTCGAGGGAGGGGCGTGG
GGAAGGCGGCGGGAGGAGGAGCGCACGGGCCGGCTGCCGTGCCCACCACGGCTGAGGAACATGGTTTTCGAGTCGGTGGTCGTGGACGTGTTGAACCGGT
TCTTGGGGGACTATGTGGTGGACTTGGACACGTCCCAGCTCTCTCTGGGCATCTGGAAAGGAGCTGTGGCCCTCAAGAATCTTCAAATTAAAGAAAATGC
CCTGAGTCAACTGGATGTACCATTTAAAGTTAAAGTTGGTCACATAGGTAATCTTAAACTTATAATTCCATGGAAAAACCTTTATACTCAACCTGTTGAA
GCCGTATTGGAAGAAATTTATTTACTTATAGTGCCTTCTTCTAGAATAAAATATGATCCTTTAAAAGAAGAGAAACAACTCATGGAAGCAAAGCAACAGG
AACTGAAAAGAATAGAAGAAGCAAAACAAAAAGTAGTTGATCAAGAACAACATCTGCCGGAAAAACAGGACACTTTTGCAGAAAAATTAGTTACACAGAT
CATAAAAAATCTTCAGGTGAAAATTTCCAGTATCCATATTCGTTATGAAGATGATATCACAAATCGGGACAAACCGCTGTCATTTGGTATTTCCCTTCAA
AATCTGAGCATGCAGACAACTGATCAATACTGGGTTCCATGTTTACATGATGAAACTGAGAAACTGGTTCGTAAGTTAATCCGATTGGATAACCTGTTTG
CCTATTGGAATGTGAAGTCTCAGATGTTTTATCTTAGTGATTATGATAACTCCTTGGACGACTTGAAGAATGGCATTGTCAATGAAAATATTGTTCCAGA
AGGTTATGATTTTGTATTTCGTCCCATATCTGCTAATGCCAAACTTGTGATGAATCGCCGATCTGATTTTGACTTTTCTGCCCCCAAAATAAACTTGGAA
ATTGAGTTACATAACATAGCAATTGAATTTAATAAACCACAGTATTTCAGTATTATGGAGCTTCTTGAATCAGTTGATATGATGGCACAAAATCTGCCAT
ATAGGAAGTTCAAACCTGATGTGCCTCTTCACCACCATGCCAGAGAATGGTGGGCTTATGCTATACATGGCGTTCTTGAAGTAAATGTTTGCCCCAGGTT
ATGGATGTGGTCATGGAAGCATATTAGAAAACATAGGCAAAAAGTGAAGCAATATAAAGAACTGTATAAAAAAAAGTTAACAAGTAAGAAGCCACCTGGT
GAACTTCTCGTGTCTTTGGAGGAGTTGGAAAAAACCTTGGATGTCTTTAATATAACTATAGCTAGACAGACGGCAGAAGTTGAGGTAAAGAAAGCTGGAT
ACAAAATTTACAAAGAAGGAGTAAAAGATCCAGAGGATAATAAAGGGTGGTTTAGCTGGCTATGGTCTTGGTCAGAACAAAATACTAATGAACAGCAACC
AGATGTTCAACCTGAAACTCTTGAAGAAATGTTGACACCTGAAGAAAAAGCTTTACTCTATGAAGCAATTGGCTATAGTGAAACAGCAGTTGATCCAACT
TTACTAAAAACATTTGAAGCCTTGAAGTTTTTTGTCCACTTGAAAAGTATGTCTATTGTTCTAAGAGAAAATCATCAAAAACCTGAGCTGGTAGATATTG
TAATAGAAGAATTTAGCACCTTAATTGTGCAAAGACCAGGAGCACAAGCAATAAAATTTGAAACTAAAATAGATTCATTTCATATTACTGGCTTACCAGA
TAATTCAGAAAAACCCCGCCTCCTGTCTTCATTGGATGATGCAATGTCACTTTTCCAAATTACATTTGAGATAAATCCATTAGATGAAACTGTTTCTCAG
AGGTGTATCATAGAAGCTGAACCTTTAGAAATCATATATGATGCAAGGACAGTGAATAGTATAGTGGAATTCTTCAGACCTCCAAAAGAGGTACATCTAG
CACAGCTCACTGCAGCAACTTTGACAAAACTGGAAGAATTTCGCAGTAAGACAGCAACAGGTCTACTGTATATTATTGAAACACAGAAAGTTCTTGATCT
CAAAATTAATTTGAAGGCTTCATATATTATTGTCCCACAAGATGGAATTTTTAGTCCTACATCAAATCTGCTTCTTTTGGACCTTGGTCATCTAAAGGTG
ACGAGTAAAAGTCGTTCTGAATTACCAGATGTGAAACAAGGTGAGGCCAATCTTAAAGAGATAATGGATAGAGCTTATGATTCATTTGATATTCAACTTA
CAAGTGTACAGCTGCTTTACAGTAGAGTTGGTGATAATTGGAGAGAAGCACGAAAACTCAGTGTATCTACCCAGCATATTTTGGTACCCATGCACTTCAA
TTTGGAACTGTCTAAGGCCATGGTTTTCATGGATGTAAGGATGCCCAAATTCAAGATTTATGGAAAGTTACCTCTTATTTCTTTACGAATCTCAGATAAA
AAACTACAAGGGATTATGGAATTGATTGAAAGCATTCCAAAACCTGAACCAGTAACTGAAGTATCTGCCCCTGTCAAATCATTCCAGATTCAAACATCTA
CTTCTTTGGGAACATCACAGATTTCACAGAAAATAATTCCTCTCTTGGAACTTCCATCTGTTTCTGAAGATGATTCAGAGGAGGAATTTTTTGATGCACC
ATGTAGTCCCTTGGAAGAACCTCTTCAGTTTCCAACTGGAGTTAAAAGTATTCGAACCAGAAAGTTACAAAAGCAGGATTGTTCAGTAAATATGACTACA
TTTAAAATAAGATTTGAAGTACCAAAGGTTTTGATCGAGTTTTATCACCTTGTTGGAGATTGTGAACTATCTGTGGTAGAAATTCTTGTTTTAGGATTGG
GTGCAGAAATTGAGATTAGAACATACGATTTGAAAGCAAATGCCTTTTTGAAAGAGTTCTGCTTAAAATGCCCAGAATACTTGGATGAAAACAAGAAACC
AGTTTATTTGGTTACAACCCTGGATAACACAATGGAAGACCTGTTAACGCTGGAATATGTAAAGGCTGAAAAGAATGTACCCGACTTGAAAAGTACCTAT
AACAATGTTTTACAATTGATTAAGGTAAATTTTTCCTCTTTGGATATTCATTTACACACTGAAGCACTTCTGAATACAATAAATTATCTTCATAATATCC
TTCCGCAATCAGAGGAAAAATCAGCCCCAGTGTCCACTACAGAGACTGAAGACAAAGGAGATGTCATTAAAAAATTAGCTTTAAAACTATCCACAAATGA
AGATATCATTACTTTGCAGATTTTAGCAGAATTATCGTGTTTACAGATCTTTATTCAAGATCAGAAATGTAACATTTCTGAAATTAAGATTGAAGGGCTT
GATTCTGAGATGATTATGAGGCCTTCAGAAACTGAAATAAACGCAAAGCTAAGGAATATAATTGTTTTAGATTCTGATATAACAGCTATATACAAAAAGG
CTGTTTATATCACTGGAAAAGAAGTTTTCAGCTTCAAAATGGTTTCTTACATGGATGCAACTGCTGGTTCTGCATACACAGATATGAATGTGGTTGACAT
TCAGGTTAATTTAATAGTTGGTTGCATTGAAGTAGTTTTTGTCACGAAATTTCTATATTCTATATTGGCTTTTATAGATAATTTTCAGGCAGCTAAACAA
GCCTTGGCTGAGGCAACTGTTCAGGCAGCTGGAATGGCTGCTACTGGTGTAAAAGAACTCGCACAAAGGAGTTCCAGAATGGCACTGGATATTAACATCA
AAGCCCCAGTTGTGGTCATCCCGCAGTCTCCAGTTTCTGAAAATGTTTTTGTTGCTGATTTTGGACTAATTACAATGACAAATACCTTTCATATGATAAC
AGAGAGCCAGAGCTCTCCCCCACCTGTTATTGATTTGATAACAATAAAGCTGAGTGAAATGCGACTATACAGATCTCGATTTATTAATGATGCATACCAG
GAAGTACTGGATCTACTCCTGCCATTAAATCTTGAGGTTGTGGTTGAACGAAATTTATGCTGGGAGTGGTACCAGGAAGTTCCTTGTTTTAATGTAAATG
CTCAGCTGAAACCAATGGAGTTCATTCTTAGTCAAGAAGATATAACAACTATTTTTAAAACATTGCATGGCAATATATGGTATGAAAAAGATGGTAGTGC
CTCACCTGCTGTAACAAAAGACCAATACAGTGCCACTAGTGGAGTTACTACTAATGCTTCACACCATTCAGGAGGAGCAACTGTGGTGACAGCTGCTGTG
GTAGAAGTACATTCACGTGCCTTACTAGTTAAGACAACACTAAACATAAGCTTCAAAACTGATGATCTCACCATGGTGCTGTATAGTCCAGGTCCTAAAC
AGGCTTCCTTTACAGATGTTCGTGATCCTTCTCTGAAACTTGCTGAATTTAAATTGGAGAATATTATAAGTACTTTAAAAATGTATACAGATGGCTCAAC
ATTTTCTTCCTTCTCATTAAAAAACTGTATTTTAGATGATAAAAGACCTCATGTCAAGAAAGCAACTCCTCGAATGATAGGACTGACAGTTGGTTTTGAC
AAAAAAGACATGATGGATATAAAGTACAGGAAAGTCAGAGATGGTTGTGTGACTGATGCGGTCTTTCAAGAAATGTATATTTGTGCAAGCGTAGAATTTC
TGCAGACTGTTGCAAATGTCTTTCTTGAGGCCTACACCACAGGCACTGCTGTAGAAACCAGTGTGCAAACATGGACTGCTAAGGAAGAAGTACCTACACA
GGAATCAGTGAAGTGGGAAATTAATGTTATTATTAAAAATCCTGAAATTGTGTTTGTAGCTGACATGACAAAAAATGATGCTCCTGCTTTAGTCATTACA
ACACAATGTGAAATTTGCTATAAAGGTAACCTTGAAAATAGTACAATGACTGCTGCCATTAAAGATCTCCAAGTGAGAGCCTGCCCGTTTCTTCCAGTCA
AGAGAAAAGGCAAAATCACTACTGTTTTGCAGCCCTGTGACTTGTTTTATCAAACTACTCAGAAAGGTACAGATCCACAAGTGATCGATATGTCAGTAAA
ATCCCTGACACTAAAGGTTTCACCAGTTATTATAAATACTATGATTACCATAACTTCAGCACTGTATACAACTAAGGAAACCATCCCAGAAGAAACGGCT
TCTTCTACTGCACATTTATGGGAAAAGAAGGATACAAAGACTTTAAAAATGTGGTTTCTTGAAGAATCAAATGAAACTGAAAAAATAGCTCCCACAACTG
AATTGGTACCCAAAGGCGAGATGATAAAAATGAACATTGATTCTATTTTTATAGTTCTTGAGGCTGGAATTGGTCATAGAACAGTACCTATGCTTCTGGC
AAAGTCACGTTTTTCAGGGGAAGGCAAAAACTGGAGTTCCCTAATAAATCTGCACTGTCAGCTTGAGCTAGAAGTGCATTATTATAATGAAATGTTTGGT
GTATGGGAGCCTTTGCTTGAACCCTTAGAAATTGATCAGACTGAGGATTTTAGACCATGGAATCTTGGTATCAAGATGAAAAAGAAAGCAAAAATGGCCA
TTGTTGAGTCAGATCCTGAAGAAGAAAACTACAAAGTGCCAGAATATAAAACTGTCATCAGTTTCCATTCAAAAGACCAATTAAACATTACATTATCCAA
ATGTGGTCTTGTAATGTTAAACAATTTAGTCAAGGCATTTACAGAAGCTGCCACTGGATCTTCAGCTGACTTCGTAAAGGATCTAGCACCATTTATGATT
TTAAATTCCCTTGGACTTACTATTTCTGTTTCGCCAAGTGATTCTTTTAGTGTACTCAACATTCCTATGGCAAAATCATATGTATTGAAAAATGGAGAAA
GTTTAAGTATGGATTATATCCGAACCAAGGACAATGATCATTTCAATGCAATGACCAGCCTAAGCAGCAAACTCTTCTTCATTCTTCTTACACCTGTTAA
CCATTCTACTGCTGATAAGATTCCTTTAACAAAAGTGGGACGACGTCTGTACACTGTAAGACACAGAGAGTCTGGCGTTGAAAGATCTATTGTTTGTCAA
ATTGATACAGTAGAAGGAAGTAAGAAGGTCACAATTCGCTCCCCAGTGCAGATAAGAAATCATTTTTCAGTCCCACTGTCTGTTTACGAAGGGGATACCT
TATTGGGAACTGCCTCACCTGAAAATGAATTCAACATACCATTAGGATCTTACCGATCATTCATTTTTCTGAAGCCAGAAGATGAGAACTATCAAATGTG
TGAAGGAATTGACTTTGAAGAGATTATAAAAAATGATGGTGCTCTTCTAAAGAAGAAATGTAGATCTAAAAACCCTTCTAAGGAATCATTTCTCATTAAT
ATTGTTCCAGAAAAAGATAATTTAACATCTCTATCAGTGTATTCAGAAGATGGTTGGGATTTACCATACATAATGCATTTGTGGCCACCTATCCTGCTCC
GAAATCTTCTTCCTTACAAAATTGCTTATTATATAGAGGGAATTGAAAATTCGGTTTTTACTCTAAGTGAAGGACATTCAGCCCAGATTTGTACTGCACA
GTTGGGTAAAGCCAGGCTACATTTAAAATTACTTGACTATCTCAATCACGATTGGAAAAGTGAATATCACATAAAGCCTAATCAGCAAGACATTAGTTTT
GTCAGTTTTACTTGTGTTACAGAAATGGAAAAGACTGATTTAGATATTGCTGTCCATATGACTTACAATACTGGTCAGACAGTTGTGGCATTTCATAGTC
CTTATTGGATGGTCAATAAAACTGGCCGCATGTTACAGTACAAAGCAGACGGAATTCATCGAAAGCATCCACCTAATTATAAAAAGCCAGTTCTCTTTTC
TTTTCAGCCAAATCACTTTTTTAATAACAATAAGGTTCAACTTATGGTAACTGATAGTGAGTTGTCCAATCAGTTTTCAATTGATACTGTTGGTAGTCAT
GGAGCTGTTAAATGTAAAGGCCTGAAAATGGACTATCAAGTTGGTGTCACTATAGACCTGAGCAGTTTTAACATTACTAGAATTGTGACATTTACCCCTT
TTTATATGATTAAAAACAAAAGCAAATACCATATATCAGTGGCTGAAGAAGGAAATGATAAATGGCTCTCTCTTGATTTGGAGCAGTGTATCCCCTTTTG
GCCTGAGTATGCTTCTAGTAAACTTCTTATTCAAGTCGAAAGGAGTGAAGATCCTCCCAAAAGGATATATTTTAACAAGCAGGAAAATTGTATTCTATTG
CGTCTAGATAACGAGCTTGGAGGTATTATAGCAGAAGTGAATTTGGCCGAGCATTCTACAGTTATTACATTTTTAGATTATCATGATGGAGCAGCTACAT
TCCTCTTAATAAATCACACAAAGAATGAACTTGTTCAATACAATCAAAGTTCTCTCAGTGAAATAGAAGATTCCCTCCCTCCTGGTAAAGCCGTGTTTTA
TACATGGGCTGATCCGGTGGGCTCTAGAAGGCTGAAGTGGAGATGTAGAAAAAGCCATGGTGAAGTAACACAGAAGGATGATATGATGATGCCTATAGAT
TTGGGGGAAAAGACAATATATTTAGTTTCATTCTTTGAAGGTTTACAACGCATTATTTTATTCACTGAAGATCCAAGGGTATTTAAAGTAACATATGAAA
GTGAGAAAGCAGAGTTAGCAGAGCAAGAAATTGCAGTGGCATTACAAGATGTTGGAATTTCTCTTGTCAACAATTACACGAAGCAAGAAGTAGCCTATAT
AGGCATTACAAGTTCTGATGTGGTTTGGGAAACAAAGCCCAAGAAGAAGGCAAGATGGAAGCCAATGAGTGTAAAGCACACTGAGAAGTTAGAGAGAGAA
TTTAAGGAATATACTGAATCTTCTCCTTCAGAAGATAAGGTTATTCAGTTGGACACTAATGTTCCGGTTCGCCTAACCCCTACTGGTCATAACATGAAAA
TTCTGCAGCCGCATGTAATAGCTCTACGAAGAAATTATCTTCCAGCATTAAAAGTGGAATATAACACATCTGCACATCAATCATCATTTAGAATTCAGAT
TTACAGAATACAGATCCAAAATCAGATACATGGTGCTGTATTTCCCTTTGTGTTTTATCCTGTTAAACCTCCAAAGTCGGTCACCATGGATTCAGCACCA
AAGCCCTTTACAGATGTCAGTATTGTCATGAGATCTGCAGGACATTCCCAGATATCACGTATTAAGTATTTCAAAGTATTGATTCAAGAAATGGATCTCA
GGTTAGATCTTGGGTTTATCTATGCTTTAACAGACCTTATGACAGAAGCTGAGGTGACTGAAAATACAGAGGTTGAGCTTTTTCATAAAGATATAGAAGC
TTTCAAAGAAGAATATAAAACAGCCTCATTAGTAGATCAATCACAAGTCAGCCTCTATGAATATTTTCATATATCTCCTATCAAGTTACATTTAAGTGTT
TCACTGAGTTCCGGCAGAGAAGAAGCTAAAGATTCAAAACAAAATGGAGGACTGATTCCAGTTCATTCTTTAAATCTTTTGCTGAAGAGTATTGGTGCCA
CACTGACAGATGTACAAGATGTAGTTTTTAAGCTTGCATTTTTTGAACTCAACTATCAGTTCCATACAACATCCGATCTACAGTCTGAAGTCATAAGACA
CTATTCAAAACAGGCCATTAAGCAGATGTATGTACTCATTCTTGGACTTGATGTTTTGGGAAATCCATTTGGCTTAATTAGAGAATTTTCTGAAGGTGTA
GAAGCATTTTTTTATGAACCTTACCAGGGAGCCATCCAGGGTCCTGAAGAGTTTGTGGAAGGAATGGCACTAGGACTTAAGGCACTAGTTGGTGGAGCTG
TTGGTGGATTGGCTGGTGCTGCCTCCAAAATCACCGGTGCTATGGCTAAGGGGGTAGCAGCTATGACCATGGATGAAGACTACCAACAGAAGAGAAGAGA
AGCCATGAATAAGCAACCAGCTGGTTTTAGAGAAGGCATCACTCGTGGAGGAAAAGGCTTAGTTTCTGGATTTGTTAGTGGCATAACAGGAATTGTTACA
AAACCAATCAAAGGAGCTCAAAAAGGAGGAGCAGCTGGTTTCTTTAAAGGTGTTGGGAAAGGTTTAGTAGGAGCGGTAGCAAGGCCAACTGGAGGCATCA
TAGACATGGCTAGCAGTACATTTCAGGGAATAAAAAGAGCTACAGAGACTTCTGAAGTGGAGAGTCTGCGACCTCCTCGGTTCTTCAATGAAGATGGAGT
TATCAGACCGTACAGGTTGAGGGATGGGACTGGAAATCAAATGTTACAGGTCATGGAAAATGGAAGATTTGCAAAATACAAATATTTTACCCATGTCATG
ATCAATAAGACAGATATGCTAATGATAACCAGACGTGGTGTATTGTTTGTAACAAAGGGAACATTTGGACAACTCACGTGTGAGTGGCAGTATAGTTTTG
ATGAATTTACCAAAGAGCCATTCATTGTTCATGGGAGAAGATTGCGCATTGAAGCAAAGGAACGAGTGAAGTCTGTATTTCATGCCAGAGAGTTTGGAAA
AATAATTAACTTCAAGACCCCAGAGGATGCCAGGTGGATCCTCACAAAGCTACAAGAAGCAAGAGAACCTTCTCCGAGCCTCTGACAGAGAACACTGCCT
GAAGACACACAGCAATAAGTGATTACAGCTCCTAGACTACCTTCCAAAACCTGTTTGGGAAGCATATTACAGAAATGATTTCAAGTACCCTGTATTCTGG
ATGCTAAAAAACAAAAACAAACAAAAAAACAAAAACAAAAAAACAAAACCAGAATCAGGTAAAACAGCTATGTGATTAAAATATTTTAATTCTTCAGCAA
TTACCCGGTTTTCTAAATTGAATCATGCATCTATTTATAATTCTAATTATTTTGTAAAAGAAGACAAAATTATGAATCTTAAGTATTTGCTCCATCTTTT
TCTCTGTAATGGTGGAGAGGCTGCCCATAATTCATCTCCACATGGAGCCAAGTTTAATGTTTCTAGTTCACATTTTGTACTTCTGTCATGCTTATTTCAA
ACTCCCTGAGTGATGGGTAAGAAATCAAACATTGCCTCAGTGGTATCAAGAGAACTTTGGTGGTGGTTTCTTCAGAATCATGAAGTTCTTTTGCCAGATA
AATATTTTGATATTATTTTCCTTTTTAATATAAAGGATAGGTTTGAATTGTACTTAAAATGCATAGCATTATTAAAAACAATCTTTTAAAATATAATTTA
TAACATAGATTGAAGCCTCCCCTTAAGAAACCTTAAAGAAATAAGTATCCTACTCAAAAAAGGAAGTCTGTTTCAGAACTTTAGGGCCTTTGAAATATTT
CCTCAAGCCTATTTCATGAGATCTACTTGGTTTACCCAAGTCATGTTTTTAATAGACTGCTAATATCAAAGGAGAATTTTTAAAGCCTTAACAATGCCTA
CTTTCCATTCACTGTTAACATGGAATAAACACAATTCCCAACATCTTAGATAGTGTATTATGCTTCCAACAGACAGTCCCTCTCATATAAAGTTTATGTA
CCCTAAAATCTAACCCAATAACCTGTCCCGTTGCCAATAGATTGAGAATTTCTGGTTTGCTTACTCTACAGTTATTCAAATGAGAGTCACGCTTTTAAAT
TTACAGCTCATCACAGAAATCATCAGCTATACATTAGTAAAAATAAGGACATGAGGTTTTCTTTCTTGGTTTTTGTCCAAGATCTTTGCACCTTAATATT
AATGGACTGTTTCAGGTAAAAGAGAATGAATGTATGATTGTGAACTGTGAAGAGAATGATGCAGGATCCTATTTAGTTACTGAATAATACAGAGTATTCA
ATGCATGTTGTATGTGCCACCAAGTTACTATTAACTGTTTTTGGAATTGAAGACTCTGTATAGTCAATAGTTGTGAAATTCTTCTCAGGCTCCTTAAACC
CTCGCTTTGTTGTAAAAGCTAAAATAAACAGCATGCTATATTGTAATTGTATTTCTTGCTGACCAAATCTACTAAATGCTATTGATTTCTCTCTGATTAC
TAAAACACATTGTTTATTCTCAGTAGTTTCCCCCAAAATGCTTTTTTCTTTGCTGAACTTAA
- refseq_VPS13A.F1 (forward primer)
- refseq_VPS13A.R1 (reverse primer)
- Single exon skipping
Frame 0
FLPLRAARPGLRRAPPPAARRLAHAS*ERPPPSLAGLARAARWASGGAAAEAAPEPVNRITSREGRG
EGGGRRSARAGCRAHHG*GTWFSSRWSWTC*TG
SWGTMWWTWTRPSSLWASGKELWPSRIFKLKKM
P*VNWMYHLKLKLVT*VILNL*FHGKTFILNLLK
PYWKKFIYL*CLLLE*NMIL*KKRNNSWKQSNR
N*KE*KKQNKK*LIKNNICRKNRTLLQKN*LHR
S*KIFR*KFPVSIFVMKMISQIGTNRCHLVFPFK
I*ACRQLINTGFHVYMMKLRNWFVS*SDWITCL
PIGM*SLRCFILVIMITPWTT*RMALSMKILFQ
KVMILYFVPYLLMPNL**IADLILTFLPPK*TWK
LSYIT*QLNLINHSISVLWSFLNQLI*WHKICH
IGSSNLMCLFTTMPENGGLMLYMAFLK*MFAPG
YGCGHGSILENIGKK*SNIKNCIKKS*QVRSHLV
NFSCLWRSWKKPWMSLI*L*LDRRQKLR*RKLD
TKFTKKE*KIQRIIKGGLAGYGLGQNKILMNSN
QMFNLKLLKKC*HLKKKLYSMKQLAIVKQQLIQL
Y*KHLKP*SFLST*KVCLLF*EKIIKNLSW*IL
**KNLAP*LCKDQEHKQ*NLKLK*IHFILLAYQ
IIQKNPASCLHWMMQCHFSKLHLR*IH*MKLFLR
GVS*KLNL*KSYMMQGQ*IV*WNSSDLQKRYI*
HSSLQQL*QNWKNFAVRQQQVYCILLKHRKFLI
SKLI*RLHILLSHKMEFLVLHQICFFWTLVI*R*
RVKVVLNYQM*NKVRPILKR*WIELMIHLIFNL
QVYSCFTVELVIIGEKHENSVYLPSIFWYPCTS
IWNCLRPWFSWM*GCPNSRFMESYLLFLYESQIK
NYKGLWN*LKAFQNLNQ*LKYLPLSNHSRFKHL
LLWEHHRFHRK*FLSWNFHLFLKMIQRRNFLMH
HVVPWKNLFSFQLELKVFEPESYKSRIVQ*I*LH
LK*DLKYQRF*SSFITLLEIVNYLW*KFLF*DW
VQKLRLEHTI*KQMPF*KSSA*NAQNTWMKTRN
QFIWLQPWITQWKTC*RWNM*RLKRMYPT*KVPI
TMFYN*LR*IFPLWIFIYTLKHF*IQ*IIFIIS
FRNQRKNQPQCPLQRLKTKEMSLKN*L*NYPQM
KISLLCRF*QNYRVYRSLFKIRNVTFLKLRLKGL
ILR*L*GLQKLK*TQS*GI*LF*ILI*QLYTKR
LFISLEKKFSASKWFLTWMQLLVLHTQI*MWLT
FRLI**LVALK*FLSRNFYILYWLL*IIFRQLNK
PWLRQLFRQLEWLLLV*KNSHKGVPEWHWILTS
KPQLWSSRSLQFLKMFLLLILD*LQ*QIPFI**
QRARALPHLLLI**Q*S*VKCDYTDLDLLMMHTR
KYWIYSCH*ILRLWLNEIYAGSGTRKFLVLM*M
LS*NQWSSFLVKKI*QLFLKHCMAIYGMKKMVV
PHLL*QKTNTVPLVELLLMLHTIQEEQLW*QLLW
*KYIHVPY*LRQH*T*ASKLMISPWCCIVQVLN
RLPLQMFVILL*NLLNLNWRIL*VL*KCIQMAQ
HFLPSH*KTVF*MIKDLMSRKQLLE**D*QLVLT
KKT*WI*STGKSEMVV*LMRSFKKCIFVQA*NF
CRLLQMSFLRPTPQALL*KPVCKHGLLRKKYLH
RNQ*SGKLMLLLKILKLCL*LT*QKMMLLL*SLQ
HNVKFAIKVTLKIVQ*LLPLKISK*EPARFFQS
REKAKSLLFCSPVTCFIKLLRKVQIHK*SICQ*
NP*H*RFHQLL*IL*LP*LQHCIQLRKPSQKKRL
LLLHIYGKRRIQRL*KCGFLKNQMKLKK*LPQL
NWYPKAR**K*TLILFL*FLRLELVIEQYLCFW
QSHVFQGKAKTGVP**ICTVSLS*KCIIIMKCLV
YGSLCLNP*KLIRLRILDHGILVSR*KRKQKWP
LLSQILKKKTTKCQNIKLSSVSIQKTN*TLHYP
NVVL*C*TI*SRHLQKLPLDLQLTS*RI*HHL*F
*IPLDLLFLFRQVILLVYSTFLWQNHMY*KMEK
V*VWIISEPRTMIISMQ*PA*AANSSSFFLHLL
TILLLIRFL*QKWDDVCTL*DTESLALKDLLFVK
LIQ*KEVRRSQFAPQCR*EIIFQSHCLFTKGIP
YWELPHLKMNSTYH*DLTDHSFF*SQKMRTIKC
VKELTLKRL*KMMVLF*RRNVDLKTLLRNHFSLI
LFQKKII*HLYQCIQKMVGIYHT*CICGHLSCS
EIFFLTKLLII*RELKIRFLL*VKDIQPRFVLH
SWVKPGYI*NYLTISITIGKVNIT*SLISKTLVL
SVLLVLQKWKRLI*ILLSI*LTILVRQLWHFIV
LIGWSIKLAACYSTKQTEFIESIHLIIKSQFSF
LFSQITFLITIRFNLW*LIVSCPISFQLILLVVM
ELLNVKA*KWTIKLVSL*T*AVLTLLEL*HLPL
FI*LKTKANTIYQWLKKEMINGSLLIWSSVSPF
GLSMLLVNFLFKSKGVKILPKGYILTSRKIVFYC
V*ITSLEVL*QK*IWPSILQLLHF*IIMMEQLH
SS**ITQRMNLFNTIKVLSVK*KIPSLLVKPCF
IHGLIRWALEG*SGDVEKAMVK*HRRMI**CL*I
WGKRQYI*FHSLKVYNALFYSLKIQGYLK*HMK
VRKQS*QSKKLQWHYKMLEFLLSTITRSKK*PI
*ALQVLMWFGKQSPRRRQDGSQ*V*STLRS*REN
LRNILNLLLQKIRLFSWTLMFRFA*PLLVIT*K
FCSRM**LYEEIIFQH*KWNITHLHINHHLEFR
FTEYRSKIRYMVLYFPLCFILLNLQSRSPWIQHQ
SPLQMSVLS*DLQDIPRYHVLSISKY*FKKWIS
G*ILGLSML*QTL*QKLR*LKIQRLSFFIKI*K
LSKKNIKQPH**INHKSASMNIFIYLLSSYI*VF
H*VPAEKKLKIQNKMED*FQFIL*IFC*RVLVP
H*QMYKM*FLSLHFLNSTISSIQHPIYSLKS*D
TIQNRPLSRCMYSFLDLMFWEIHLA*LENFLKV*
KHFFMNLTREPSRVLKSLWKEWH*DLRH*LVEL
LVDWLVLPPKSPVLWLRG*QL*PWMKTTNRREE
KP*ISNQLVLEKASLVEEKA*FLDLLVA*QELLQ
NQSKELKKEEQLVSLKVLGKV**ER*QGQLEAS
*TWLAVHFRE*KELQRLLKWRVCDLLGSSMKME
LSDRTG*GMGLEIKCYRSWKMEDLQNTNILPMS*
SIRQIC***PDVVYCL*QREHLDNSRVSGSIVL
MNLPKSHSLFMGEDCALKQRNE*SLYFMPESLE
K*LTSRPQRMPGGSSQSYKKQENLLRASDREHCL
KTHSNK*LQLLDYLPKPVWEAYYRNDFKYPVFW
MLKNKNKQKNKNKKTKPESGKTAM*LKYFNSSA
ITRFSKLNHASIYNSNYFVKEDKIMNLKYLLHLF
LCNGGEAAHNSSPHGAKFNVSSSHFVLLSCLFQ
TP*VMGKKSNIASVVSRELWWWFLQNHEVLLPD
KYFDIIFLFNIKDRFELYLKCIALLKTIF*NIIY
NID*SLPLRNLKEISILLKKGSLFQNFRAFEIF
PQAYFMRSTWFTQVMFLIDC*YQRRIFKALTMP
TFHSLLTWNKHNSQHLR*CIMLPTDSPSHIKFMY
PKI*PNNLSRCQ*IENFWFAYSTVIQMRVTLLN
LQLITEIISYTLVKIRT*GFLSWFLSKIFAP*Y
*WTVSGKRE*MYDCEL*RE*CRILFSY*IIQSIQ
CMLYVPPSYY*LFLELKTLYSQ*L*NSSQAP*T
LALL*KLK*TACYIVIVFLADQIY*MLLISL*L
LKHIVYSQ*FPPKCFFLC*T*
Frame 1
SSLSGLRAQVCAALRLQPRADLRTRRESDRLRLSLGSLGLRVGPAGAPQLKPPRSR*TELPRGRGV
GKAAGGGAHGPAAVPTTAEEHGFRVGGRGRVEPV
LGGLCGGLGHVPALSGHLERSCGPQESSN*RKC
PESTGCTI*S*SWSHR*S*TYNSMEKPLYSTC*
SRIGRNLFTYSAFF*NKI*SFKRRETTHGSKATG
TEKNRRSKTKSS*SRTTSAGKTGHFCRKISYTD
HKKSSGENFQYPYSL*R*YHKSGQTAVIWYFPS
KSEHADN*SILGSMFT**N*ETGS*VNPIG*PVC
LLECEVSDVLS**L**LLGRLEEWHCQ*KYCSR
RL*FCISSHIC*CQTCDESPI*F*LFCPQNKLG
N*VT*HSN*I**TTVFQYYGAS*IS*YDGTKSAI
*EVQT*CASSPPCQRMVGLCYTWRS*SKCLPQV
MDVVMEAY*KT*AKSEAI*RTV*KKVNK*EATW
*TSRVFGGVGKNLGCL*YNYS*TDGRS*GKESWI
QNLQRRSKRSRG**RVV*LAMVLVRTKY**TAT
RCST*NS*RNVDT*RKSFTL*SNWL**NSS*SN
FTKNI*SLEVFCPLEKYVYCSKRKSSKT*AGRYC
NRRI*HLNCAKTRSTSNKI*N*NRFISYYWLTR
*FRKTPPPVFIG*CNVTFPNYI*DKSIR*NCFS
EVYHRS*TFRNHI*CKDSE*YSGILQTSKRGTSS
TAHCSNFDKTGRISQ*DSNRSTVYY*NTESS*S
QN*FEGFIYYCPTRWNF*SYIKSASFGPWSSKG
DE*KSF*ITRCETR*GQS*RDNG*SL*FI*YSTY
KCTAALQ*SW**LERSTKTQCIYPAYFGTHALQ
FGTV*GHGFHGCKDAQIQDLWKVTSYFFTNLR*
KTTRDYGID*KHSKT*TSN*SICPCQIIPDSNIY
FFGNITDFTENNSSLGTSICF*R*FRGGIF*CT
M*SLGRTSSVSNWS*KYSNQKVTKAGLFSKYDY
I*NKI*STKGFDRVLSPCWRL*TICGRNSCFRIG
CRN*D*NIRFESKCLFERVLLKMPRILG*KQET
SLFGYNPG*HNGRPVNAGICKG*KECTRLEKYL
*QCFTID*GKFFLFGYSFTH*STSEYNKLSS*YP
SAIRGKISPSVHYRD*RQRRCH*KISFKTIHK*
RYHYFADFSRIIVFTDLYSRSEM*HF*N*D*RA
*F*DDYEAFRN*NKRKAKEYNCFRF*YNSYIQKG
CLYHWKRSFQLQNGFLHGCNCWFCIHRYECG*H
SG*FNSWLH*SSFCHEISIFYIGFYR*FSGS*T
SLG*GNCSGSWNGCYWCKRTRTKEFQNGTGY*HQ
SPSCGHPAVSSF*KCFCC*FWTNYNDKYLSYDN
REPELSPTCY*FDNNKAE*NATIQISIY**CIP
GSTGSTPAIKS*GCG*TKFMLGVVPGSSLF*CKC
SAETNGVHS*SRRYNNYF*NIAWQYMV*KRW*C
LTCCNKRPIQCH*WSYY*CFTPFRRSNCGDSCC
GRSTFTCLTS*DNTKHKLQN**SHHGAV*SRS*T
GFLYRCS*SFSETC*I*IGEYYKYFKNVYRWLN
IFFLLIKKLYFR**KTSCQESNSSNDRTDSWF*
QKRHDGYKVQESQRWLCD*CGLSRNVYLCKRRIS
ADCCKCLS*GLHHRHCCRNQCANMDC*GRSTYT
GISEVGN*CYY*KS*NCVCS*HDKK*CSCFSHY
NTM*NLL*R*P*K*YNDCCH*RSPSESLPVSSSQ
EKRQNHYCFAAL*LVLSNYSERYRSTSDRYVSK
IPDTKGFTSYYKYYDYHNFSTVYN*GNHPRRNG
FFYCTFMGKEGYKDFKNVVS*RIK*N*KNSSHN*
IGTQRRDDKNEH*FYFYSS*GWNWS*NSTYASG
KVTFFRGRQKLEFPNKSALSA*ARSALL**NVW
CMGAFA*TLRN*SD*GF*TMESWYQDEKESKNGH
C*VRS*RRKLQSARI*NCHQFPFKRPIKHYIIQ
MWSCNVKQFSQGIYRSCHWIFS*LRKGSSTIYD
FKFPWTYYFCFAK*FF*CTQHSYGKIICIEKWRK
FKYGLYPNQGQ*SFQCNDQPKQQTLLHSSYTC*
PFYC**DSFNKSGTTSVHCKTQRVWR*KIYCLS
N*YSRRK*EGHNSLPSADKKSFFSPTVCLRRGYL
IGNCLT*K*IQHTIRILPIIHFSEARR*ELSNV
*RN*L*RDYKK*WCSSKEEM*I*KPF*GIISH*
YCSRKR*FNISISVFRRWLGFTIHNAFVATYPAP
KSSSLQNCLLYRGN*KFGFYSK*RTFSPDLYCT
VG*SQATFKIT*LSQSRLEK*ISHKA*SARH*F
CQFYLCYRNGKD*FRYCCPYDLQYWSDSCGIS*S
LLDGQ*NWPHVTVQSRRNSSKAST*L*KASSLF
FSAKSLF**Q*GSTYGN***VVQSVFN*YCW*S
WSC*M*RPENGLSSWCHYRPEQF*HY*NCDIYPF
LYD*KQKQIPYISG*RRK**MALS*FGAVYPLL
A*VCF**TSYSSRKE*RSSQKDIF*QAGKLYSI
ASR*RAWRYYSRSEFGRAFYSYYIFRLS*WSSYI
PLNKSHKE*TCSIQSKFSQ*NRRFPPSW*SRVL
YMG*SGGL*KAEVEM*KKPW*SNTEG*YDDAYR
FGGKDNIFSFIL*RFTTHYFIH*RSKGI*SNI*K
*ESRVSRARNCSGITRCWNFSCQQLHEARSSLY
RHYKF*CGLGNKAQEEGKMEANECKAH*EVRER
I*GIY*IFSFRR*GYSVGH*CSGSPNPYWS*HEN
SAAACNSSTKKLSSSIKSGI*HICTSIII*NSD
LQNTDPKSDTWCCISLCVLSC*TSKVGHHGFST
KALYRCQYCHEICRTFPDITY*VFQSIDSRNGSQ
VRSWVYLCFNRPYDRS*GD*KYRG*AFS*RYRS
FQRRI*NSLISRSITSQPL*IFSYISYQVTFKC
FTEFRQRRS*RFKTKWRTDSSSFFKSFAEEYWCH
TDRCTRCSF*ACIF*TQLSVPYNIRSTV*SHKT
LFKTGH*ADVCTHSWT*CFGKSIWLN*RIF*RC
RSIFL*TLPGSHPGS*RVCGRNGTRT*GTSWWSC
WWIGWCCLQNHRCYG*GGSSYDHG*RLPTEEKR
SHE*ATSWF*RRHHSWRKRLSFWIC*WHNRNCY
KTNQRSSKRRSSWFL*RCWERFSRSGSKANWRHH
RHG*QYISGNKKSYRDF*SGESATSSVLQ*RWS
YQTVQVEGWDWKSNVTGHGKWKICKIQIFYPCH
DQ*DRYANDNQTWCIVCNKGNIWTTHV*VAV*F*
*IYQRAIHCSWEKIAH*SKGTSEVCISCQRVWK
NN*LQDPRGCQVDPHKATRSKRTFSEPLTENTA
*RHTAISDYSS*TTFQNLFGKHITEMISSTLYSG
C*KTKTNKKTKTKKQNQNQVKQLCD*NILILQQ
LPGFLN*IMHLFIILIIL*KKTKL*ILSICSIF
FSVMVERLPIIHLHMEPSLMFLVHILYFCHAYFK
LPE*WVRNQTLPQWYQENFGGGFFRIMKFFCQI
NILILFSFLI*RIGLNCT*NA*HY*KQSFKI*F
IT*IEASP*ETLKK*VSYSKKEVCFRTLGPLKYF
LKPIS*DLLGLPKSCF**TANIKGEFLKP*QCL
LSIHC*HGINTIPNILDSVLCFQQTVPLI*SLC
TLKSNPITCPVANRLRISGLLTLQLFK*ESRF*I
YSSSQKSSAIH**K*GHEVFFLGFCPRSLHLNI
NGLFQVKENECMIVNCEENDAGSYLVTE*YRVF
NACCMCHQVTINCFWN*RLCIVNSCEILLRLLKP
SLCCKS*NKQHAIL*LYFLLTKSTKCY*FLSDY
*NTLFILSSFPQNAFFFAEL
Frame 2
PPSQGCAPRSAPRSASSRAQTCARVVRATASVSRWAR*GCALGQRGRRS*SRPGAGEPNYLEGGAW
GRRREEERTGRLPCPPRLRNMVFESVVVDVLNR
FLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENA
LSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVE
AVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQ
ELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQI
IKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ
NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLF
AYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPE
GYDFVFRPISANAKLVMNRRSDFDFSAPKINLE
IELHNIAIEFNKPQYFSIMELLESVDMMAQNLP
YRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRL
WMWSWKHIRKHRQKVKQYKELYKKKLTSKKPPG
ELLVSLEELEKTLDVFNITIARQTAEVEVKKAG
YKIYKEGVKDPEDNKGWFSWLWSWSEQNTNEQQP
DVQPETLEEMLTPEEKALLYEAIGYSETAVDPT
LLKTFEALKFFVHLKSMSIVLRENHQKPELVDI
VIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPD
NSEKPRLLSSLDDAMSLFQITFEINPLDETVSQ
RCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHL
AQLTAATLTKLEEFRSKTATGLLYIIETQKVLDL
KINLKASYIIVPQDGIFSPTSNLLLLDLGHLKV
TSKSRSELPDVKQGEANLKEIMDRAYDSFDIQL
TSVQLLYSRVGDNWREARKLSVSTQHILVPMHFN
LELSKAMVFMDVRMPKFKIYGKLPLISLRISDK
KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTS
TSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAP
CSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTT
FKIRFEVPKVLIEFYHLVGDCELSVVEILVLGL
GAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKP
VYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTY
NNVLQLIKVNFSSLDIHLHTEALLNTINYLHNI
LPQSEEKSAPVSTTETEDKGDVIKKLALKLSTNE
DIITLQILAELSCLQIFIQDQKCNISEIKIEGL
DSEMIMRPSETEINAKLRNIIVLDSDITAIYKK
AVYITGKEVFSFKMVSYMDATAGSAYTDMNVVDI
QVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQ
ALAEATVQAAGMAATGVKELAQRSSRMALDINI
KAPVVVIPQSPVSENVFVADFGLITMTNTFHMIT
ESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQ
EVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVN
AQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSA
SPAVTKDQYSATSGVTTNASHHSGGATVVTAAV
VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPK
QASFTDVRDPSLKLAEFKLENIISTLKMYTDGST
FSSFSLKNCILDDKRPHVKKATPRMIGLTVGFD
KKDMMDIKYRKVRDGCVTDAVFQEMYICASVEF
LQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQ
ESVKWEINVIIKNPEIVFVADMTKNDAPALVIT
TQCEICYKGNLENSTMTAAIKDLQVRACPFLPV
KRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK
SLTLKVSPVIINTMITITSALYTTKETIPEETA
SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTT
ELVPKGEMIKMNIDSIFIVLEAGIGHRTVPMLLA
KSRFSGEGKNWSSLINLHCQLELEVHYYNEMFG
VWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMA
IVESDPEEENYKVPEYKTVISFHSKDQLNITLSK
CGLVMLNNLVKAFTEAATGSSADFVKDLAPFMI
LNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGE
SLSMDYIRTKDNDHFNAMTSLSSKLFFILLTPVN
HSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ
IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDT
LLGTASPENEFNIPLGSYRSFIFLKPEDENYQMC
EGIDFEEIIKNDGALLKKKCRSKNPSKESFLIN
IVPEKDNLTSLSVYSEDGWDLPYIMHLWPPILL
RNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQ
LGKARLHLKLLDYLNHDWKSEYHIKPNQQDISF
VSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHS
PYWMVNKTGRMLQYKADGIHRKHPPNYKKPVLFS
FQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH
GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTP
FYMIKNKSKYHISVAEEGNDKWLSLDLEQCIPFW
PEYASSKLLIQVERSEDPPKRIYFNKQENCILL
RLDNELGGIIAEVNLAEHSTVITFLDYHDGAAT
FLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFY
TWADPVGSRRLKWRCRKSHGEVTQKDDMMMPID
LGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYE
SEKAELAEQEIAVALQDVGISLVNNYTKQEVAYI
GITSSDVVWETKPKKKARWKPMSVKHTEKLERE
FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMK
ILQPHVIALRRNYLPALKVEYNTSAHQSSFRIQI
YRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAP
KPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDL
RLDLGFIYALTDLMTEAEVTENTEVELFHKDIEA
FKEEYKTASLVDQSQVSLYEYFHISPIKLHLSV
SLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGA
TLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRH
YSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV
EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGA
VGGLAGAASKITGAMAKGVAAMTMDEDYQQKRRE
AMNKQPAGFREGITRGGKGLVSGFVSGITGIVT
KPIKGAQKGGAAGFFKGVGKGLVGAVARPTGGI
IDMASSTFQGIKRATETSEVESLRPPRFFNEDGV
IRPYRLRDGTGNQMLQVMENGRFAKYKYFTHVM
INKTDMLMITRRGVLFVTKGTFGQLTCEWQYSF
DEFTKEPFIVHGRRLRIEAKERVKSVFHAREFGK
IINFKTPEDARWILTKLQEAREPSPSL*QRTLP
EDTQQ*VITAPRLPSKTCLGSILQK*FQVPCIL
DAKKQKQTKKQKQKNKTRIR*NSYVIKIF*FFSN
YPVF*IESCIYL*F*LFCKRRQNYES*VFAPSF
SL*WWRGCP*FISTWSQV*CF*FTFCTSVMLIS
NSLSDG*EIKHCLSGIKRTLVVVSSES*SSFAR*
IF*YYFPF*YKG*V*IVLKMHSIIKNNLLKYNL
*HRLKPPLKKP*RNKYPTQKRKSVSEL*GL*NI
SSSLFHEIYLVYPSHVFNRLLISKENF*SLNNAY
FPFTVNME*TQFPTS*IVYYASNRQSLSYKVYV
P*NLTQ*PVPLPID*EFLVCLLYSYSNESHAFK
FTAHHRNHQLYISKNKDMRFSFLVFVQDLCTLIL
MDCFR*KRMNV*L*TVKRMMQDPI*LLNNTEYS
MHVVCATKLLLTVFGIEDSV*SIVVKFFSGSLN
PRFVVKAKINSMLYCNCISC*PNLLNAIDFSLIT
KTHCLFSVVSPKMLFSLLNL
Sequence NM_001018038
TTCCTCCCTCTCAGGGCTGCGCGCCCAGGTCTGCGCCGCGCTCCGCCTCCAGCCGCGCGCAGACTTGCGCACGCGTCGTGAGAGCGACCGCCTCCGTCTCTCGCTGGGCTCGCTAGGGCTGCGCGTTGGGCCAGCGGGGGCGCCGCAGCTGAAGCCGCCCCGGAGCCGGTGAACCGAATTACCTCGAGGGAGGGGCGTGG
GGAAGGCGGCGGGAGGAGGAGCGCACGGGCCGGCTGCCGTGCCCACCACGGCTGAGGAACATGGTTTTCGAGTCGGTGGTCGTGGACGTGTTGAACCGGT
TCTTGGGGGACTATGTGGTGGACTTGGACACGTCCCAGCTCTCTCTGGGCATCTGGAAAGGAGCTGTGGCCCTCAAGAATCTTCAAATTAAAGAAAATGC
CCTGAGTCAACTGGATGTACCATTTAAAGTTAAAGTTGGTCACATAGGTAATCTTAAACTTATAATTCCATGGAAAAACCTTTATACTCAACCTGTTGAA
GCCGTATTGGAAGAAATTTATTTACTTATAGTGCCTTCTTCTAGAATAAAATATGATCCTTTAAAAGAAGAGAAACAACTCATGGAAGCAAAGCAACAGG
AACTGAAAAGAATAGAAGAAGCAAAACAAAAAGTAGTTGATCAAGAACAACATCTGCCGGAAAAACAGGACACTTTTGCAGAAAAATTAGTTACACAGAT
CATAAAAAATCTTCAGGTGAAAATTTCCAGTATCCATATTCGTTATGAAGATGATATCACAAATCGGGACAAACCGCTGTCATTTGGTATTTCCCTTCAA
AATCTGAGCATGCAGACAACTGATCAATACTGGGTTCCATGTTTACATGATGAAACTGAGAAACTGGTTCGTAAGTTAATCCGATTGGATAACCTGTTTG
CCTATTGGAATGTGAAGTCTCAGATGTTTTATCTTAGTGATTATGATAACTCCTTGGACGACTTGAAGAATGGCATTGTCAATGAAAATATTGTTCCAGA
AGGTTATGATTTTGTATTTCGTCCCATATCTGCTAATGCCAAACTTGTGATGAATCGCCGATCTGATTTTGACTTTTCTGCCCCCAAAATAAACTTGGAA
ATTGAGTTACATAACATAGCAATTGAATTTAATAAACCACAGTATTTCAGTATTATGGAGCTTCTTGAATCAGTTGATATGATGGCACAAAATCTGCCAT
ATAGGAAGTTCAAACCTGATGTGCCTCTTCACCACCATGCCAGAGAATGGTGGGCTTATGCTATACATGGCGTTCTTGAAGTAAATGTTTGCCCCAGGTT
ATGGATGTGGTCATGGAAGCATATTAGAAAACATAGGCAAAAAGTGAAGCAATATAAAGAACTGTATAAAAAAAAGTTAACAAGTAAGAAGCCACCTGGT
GAACTTCTCGTGTCTTTGGAGGAGTTGGAAAAAACCTTGGATGTCTTTAATATAACTATAGCTAGACAGACGGCAGAAGTTGAGGTAAAGAAAGCTGGAT
ACAAAATTTACAAAGAAGGAGTAAAAGATCCAGAGGATAATAAAGGGTGGTTTAGCTGGCTATGGTCTTGGTCAGAACAAAATACTAATGAACAGCAACC
AGATGTTCAACCTGAAACTCTTGAAGAAATGTTGACACCTGAAGAAAAAGCTTTACTCTATGAAGCAATTGGCTATAGTGAAACAGCAGTTGATCCAACT
TTACTAAAAACATTTGAAGCCTTGAAGTTTTTTGTCCACTTGAAAAGTATGTCTATTGTTCTAAGAGAAAATCATCAAAAACCTGAGCTGGTAGATATTG
TAATAGAAGAATTTAGCACCTTAATTGTGCAAAGACCAGGAGCACAAGCAATAAAATTTGAAACTAAAATAGATTCATTTCATATTACTGGCTTACCAGA
TAATTCAGAAAAACCCCGCCTCCTGTCTTCATTGGATGATGCAATGTCACTTTTCCAAATTACATTTGAGATAAATCCATTAGATGAAACTGTTTCTCAG
AGGTGTATCATAGAAGCTGAACCTTTAGAAATCATATATGATGCAAGGACAGTGAATAGTATAGTGGAATTCTTCAGACCTCCAAAAGAGGTACATCTAG
CACAGCTCACTGCAGCAACTTTGACAAAACTGGAAGAATTTCGCAGTAAGACAGCAACAGGTCTACTGTATATTATTGAAACACAGAAAGTTCTTGATCT
CAAAATTAATTTGAAGGCTTCATATATTATTGTCCCACAAGATGGAATTTTTAGTCCTACATCAAATCTGCTTCTTTTGGACCTTGGTCATCTAAAGGTG
ACGAGTAAAAGTCGTTCTGAATTACCAGATGTGAAACAAGGTGAGGCCAATCTTAAAGAGATAATGGATAGAGCTTATGATTCATTTGATATTCAACTTA
CAAGTGTACAGCTGCTTTACAGTAGAGTTGGTGATAATTGGAGAGAAGCACGAAAACTCAGTGTATCTACCCAGCATATTTTGGTACCCATGCACTTCAA
TTTGGAACTGTCTAAGGCCATGGTTTTCATGGATGTAAGGATGCCCAAATTCAAGATTTATGGAAAGTTACCTCTTATTTCTTTACGAATCTCAGATAAA
AAACTACAAGGGATTATGGAATTGATTGAAAGCATTCCAAAACCTGAACCAGTAACTGAAGTATCTGCCCCTGTCAAATCATTCCAGATTCAAACATCTA
CTTCTTTGGGAACATCACAGATTTCACAGAAAATAATTCCTCTCTTGGAACTTCCATCTGTTTCTGAAGATGATTCAGAGGAGGAATTTTTTGATGCACC
ATGTAGTCCCTTGGAAGAACCTCTTCAGTTTCCAACTGGAGTTAAAAGTATTCGAACCAGAAAGTTACAAAAGCAGGATTGTTCAGTAAATATGACTACA
TTTAAAATAAGATTTGAAGTACCAAAGGTTTTGATCGAGTTTTATCACCTTGTTGGAGATTGTGAACTATCTGTGGTAGAAATTCTTGTTTTAGGATTGG
GTGCAGAAATTGAGATTAGAACATACGATTTGAAAGCAAATGCCTTTTTGAAAGAGTTCTGCTTAAAATGCCCAGAATACTTGGATGAAAACAAGAAACC
AGTTTATTTGGTTACAACCCTGGATAACACAATGGAAGACCTGTTAACGCTGGAATATGTAAAGGCTGAAAAGAATGTACCCGACTTGAAAAGTACCTAT
AACAATGTTTTACAATTGATTAAGGTAAATTTTTCCTCTTTGGATATTCATTTACACACTGAAGCACTTCTGAATACAATAAATTATCTTCATAATATCC
TTCCGCAATCAGAGGAAAAATCAGCCCCAGTGTCCACTACAGAGACTGAAGACAAAGGAGATGTCATTAAAAAATTAGCTTTAAAACTATCCACAAATGA
AGATATCATTACTTTGCAGATTTTAGCAGAATTATCGTGTTTACAGATCTTTATTCAAGATCAGAAATGTAACATTTCTGAAATTAAGATTGAAGGGCTT
GATTCTGAGATGATTATGAGGCCTTCAGAAACTGAAATAAACGCAAAGCTAAGGAATATAATTGTTTTAGATTCTGATATAACAGCTATATACAAAAAGG
CTGTTTATATCACTGGAAAAGAAGTTTTCAGCTTCAAAATGGTTTCTTACATGGATGCAACTGCTGGTTCTGCATACACAGATATGAATGTGGTTGACAT
TCAGGTTAATTTAATAGTTGGTTGCATTGAAGTAGTTTTTGTCACGAAATTTCTATATTCTATATTGGCTTTTATAGATAATTTTCAGGCAGCTAAACAA
GCCTTGGCTGAGGCAACTGTTCAGGCAGCTGGAATGGCTGCTACTGGTGTAAAAGAACTCGCACAAAGGAGTTCCAGAATGGCACTGGATATTAACATCA
AAGCCCCAGTTGTGGTCATCCCGCAGTCTCCAGTTTCTGAAAATGTTTTTGTTGCTGATTTTGGACTAATTACAATGACAAATACCTTTCATATGATAAC
AGAGAGCCAGAGCTCTCCCCCACCTGTTATTGATTTGATAACAATAAAGCTGAGTGAAATGCGACTATACAGATCTCGATTTATTAATGATGCATACCAG
GAAGTACTGGATCTACTCCTGCCATTAAATCTTGAGGTTGTGGTTGAACGAAATTTATGCTGGGAGTGGTACCAGGAAGTTCCTTGTTTTAATGTAAATG
CTCAGCTGAAACCAATGGAGTTCATTCTTAGTCAAGAAGATATAACAACTATTTTTAAAACATTGCATGGCAATATATGGTATGAAAAAGATGGTAGTGC
CTCACCTGCTGTAACAAAAGACCAATACAGTGCCACTAGTGGAGTTACTACTAATGCTTCACACCATTCAGGAGGAGCAACTGTGGTGACAGCTGCTGTG
GTAGAAGTACATTCACGTGCCTTACTAGTTAAGACAACACTAAACATAAGCTTCAAAACTGATGATCTCACCATGGTGCTGTATAGTCCAGGTCCTAAAC
AGGCTTCCTTTACAGATGTTCGTGATCCTTCTCTGAAACTTGCTGAATTTAAATTGGAGAATATTATAAGTACTTTAAAAATGTATACAGATGGCTCAAC
ATTTTCTTCCTTCTCATTAAAAAACTGTATTTTAGATGATAAAAGACCTCATGTCAAGAAAGCAACTCCTCGAATGATAGGACTGACAGTTGGTTTTGAC
AAAAAAGACATGATGGATATAAAGTACAGGAAAGTCAGAGATGGTTGTGTGACTGATGCGGTCTTTCAAGAAATGTATATTTGTGCAAGCGTAGAATTTC
TGCAGACTGTTGCAAATGTCTTTCTTGAGGCCTACACCACAGGCACTGCTGTAGAAACCAGTGTGCAAACATGGACTGCTAAGGAAGAAGTACCTACACA
GGAATCAGTGAAGTGGGAAATTAATGTTATTATTAAAAATCCTGAAATTGTGTTTGTAGCTGACATGACAAAAAATGATGCTCCTGCTTTAGTCATTACA
ACACAATGTGAAATTTGCTATAAAGGTAACCTTGAAAATAGTACAATGACTGCTGCCATTAAAGATCTCCAAGTGAGAGCCTGCCCGTTTCTTCCAGTCA
AGAGAAAAGGCAAAATCACTACTGTTTTGCAGCCCTGTGACTTGTTTTATCAAACTACTCAGAAAGGTACAGATCCACAAGTGATCGATATGTCAGTAAA
ATCCCTGACACTAAAGGTTTCACCAGTTATTATAAATACTATGATTACCATAACTTCAGCACTGTATACAACTAAGGAAACCATCCCAGAAGAAACGGCT
TCTTCTACTGCACATTTATGGGAAAAGAAGGATACAAAGACTTTAAAAATGTGGTTTCTTGAAGAATCAAATGAAACTGAAAAAATAGCTCCCACAACTG
AATTGGTACCCAAAGGCGAGATGATAAAAATGAACATTGATTCTATTTTTATAGTTCTTGAGGCTGGAATTGGTCATAGAACAGTACCTATGCTTCTGGC
AAAGTCACGTTTTTCAGGGGAAGGCAAAAACTGGAGTTCCCTAATAAATCTGCACTGTCAGCTTGAGCTAGAAGTGCATTATTATAATGAAATGTTTGGT
GTATGGGAGCCTTTGCTTGAACCCTTAGAAATTGATCAGACTGAGGATTTTAGACCATGGAATCTTGGTATCAAGATGAAAAAGAAAGCAAAAATGGCCA
TTGTTGAGTCAGATCCTGAAGAAGAAAACTACAAAGTGCCAGAATATAAAACTGTCATCAGTTTCCATTCAAAAGACCAATTAAACATTACATTATCCAA
ATGTGGTCTTGTAATGTTAAACAATTTAGTCAAGGCATTTACAGAAGCTGCCACTGGATCTTCAGCTGACTTCGTAAAGGATCTAGCACCATTTATGATT
TTAAATTCCCTTGGACTTACTATTTCTGTTTCGCCAAGTGATTCTTTTAGTGTACTCAACATTCCTATGGCAAAATCATATGTATTGAAAAATGGAGAAA
GTTTAAGTATGGATTATATCCGAACCAAGGACAATGATCATTTCAATGCAATGACCAGCCTAAGCAGCAAACTCTTCTTCATTCTTCTTACACCTGTTAA
CCATTCTACTGCTGATAAGATTCCTTTAACAAAAGTGGGACGACGTCTGTACACTGTAAGACACAGAGAGTCTGGCGTTGAAAGATCTATTGTTTGTCAA
ATTGATACAGTAGAAGGAAGTAAGAAGGTCACAATTCGCTCCCCAGTGCAGATAAGAAATCATTTTTCAGTCCCACTGTCTGTTTACGAAGGGGATACCT
TATTGGGAACTGCCTCACCTGAAAATGAATTCAACATACCATTAGGATCTTACCGATCATTCATTTTTCTGAAGCCAGAAGATGAGAACTATCAAATGTG
TGAAGGAATTGACTTTGAAGAGATTATAAAAAATGATGGTGCTCTTCTAAAGAAGAAATGTAGATCTAAAAACCCTTCTAAGGAATCATTTCTCATTAAT
ATTGTTCCAGAAAAAGATAATTTAACATCTCTATCAGTGTATTCAGAAGATGGTTGGGATTTACCATACATAATGCATTTGTGGCCACCTATCCTGCTCC
GAAATCTTCTTCCTTACAAAATTGCTTATTATATAGAGGGAATTGAAAATTCGGTTTTTACTCTAAGTGAAGGACATTCAGCCCAGATTTGTACTGCACA
GTTGGGTAAAGCCAGGCTACATTTAAAATTACTTGACTATCTCAATCACGATTGGAAAAGTGAATATCACATAAAGCCTAATCAGCAAGACATTAGTTTT
GTCAGTTTTACTTGTGTTACAGAAATGGAAAAGACTGATTTAGATATTGCTGTCCATATGACTTACAATACTGGTCAGACAGTTGTGGCATTTCATAGTC
CTTATTGGATGGTCAATAAAACTGGCCGCATGTTACAGTACAAAGCAGACGGAATTCATCGAAAGCATCCACCTAATTATAAAAAGCCAGTTCTCTTTTC
TTTTCAGCCAAATCACTTTTTTAATAACAATAAGGTTCAACTTATGGTAACTGATAGTGAGTTGTCCAATCAGTTTTCAATTGATACTGTTGGTAGTCAT
GGAGCTGTTAAATGTAAAGGCCTGAAAATGGACTATCAAGTTGGTGTCACTATAGACCTGAGCAGTTTTAACATTACTAGAATTGTGACATTTACCCCTT
TTTATATGATTAAAAACAAAAGCAAATACCATATATCAGTGGCTGAAGAAGGAAATGATAAATGGCTCTCTCTTGATTTGGAGCAGTGTATCCCCTTTTG
GCCTGAGTATGCTTCTAGTAAACTTCTTATTCAAGTCGAAAGGAGTGAAGATCCTCCCAAAAGGATATATTTTAACAAGCAGGAAAATTGTATTCTATTG
CGTCTAGATAACGAGCTTGGAGGTATTATAGCAGAAGTGAATTTGGCCGAGCATTCTACAGTTATTACATTTTTAGATTATCATGATGGAGCAGCTACAT
TCCTCTTAATAAATCACACAAAGAATGAACTTGTTCAATACAATCAAAGTTCTCTCAGTGAAATAGAAGATTCCCTCCCTCCTGGTAAAGCCGTGTTTTA
TACATGGGCTGATCCGGTGGGCTCTAGAAGGCTGAAGTGGAGATGTAGAAAAAGCCATGGTGAAGTAACACAGAAGGATGATATGATGATGCCTATAGAT
TTGGGGGAAAAGACAATATATTTAGTTTCATTCTTTGAAGGTTTACAACGCATTATTTTATTCACTGAAGATCCAAGGGTATTTAAAGTAACATATGAAA
GTGAGAAAGCAGAGTTAGCAGAGCAAGAAATTGCAGTGGCATTACAAGATGTTGGAATTTCTCTTGTCAACAATTACACGAAGCAAGAAGTAGCCTATAT
AGGCATTACAAGTTCTGATGTGGTTTGGGAAACAAAGCCCAAGAAGAAGGCAAGATGGAAGCCAATGAGTGTAAAGCACACTGAGAAGTTAGAGAGAGAA
TTTAAGGAATATACTGAATCTTCTCCTTCAGAAGATAAGGTTATTCAGTTGGACACTAATGTTCCGGTTCGCCTAACCCCTACTGGTCATAACATGAAAA
TTCTGCAGCCGCATGTAATAGCTCTACGAAGAAATTATCTTCCAGCATTAAAAGTGGAATATAACACATCTGCACATCAATCATCATTTAGAATTCAGAT
TTACAGAATACAGATCCAAAATCAGATACATGGTGCTGTATTTCCCTTTGTGTTTTATCCTGTTAAACCTCCAAAGTCGGTCACCATGGATTCAGCACCA
AAGCCCTTTACAGATGTCAGTATTGTCATGAGATCTGCAGGACATTCCCAGATATCACGTATTAAGTATTTCAAAGTATTGATTCAAGAAATGGATCTCA
GGTTAGATCTTGGGTTTATCTATGCTTTAACAGACCTTATGACAGAAGCTGAGGTGACTGAAAATACAGAGGTTGAGCTTTTTCATAAAGATATAGAAGC
TTTCAAAGAAGAATATAAAACAGCCTCATTAGTAGATCAATCACAAGTCAGCCTCTATGAATATTTTCATATATCTCCTATCAAGTTACATTTAAGTGTT
TCACTGAGTTCCGGCAGAGAAGAAGCTAAAGATTCAAAACAAAATGGAGGACTGATTCCAGTTCATTCTTTAAATCTTTTGCTGAAGAGTATTGGTGCCA
CACTGACAGATGTACAAGATGTAGTTTTTAAGCTTGCATTTTTTGAACTCAACTATCAGTTCCATACAACATCCGATCTACAGTCTGAAGTCATAAGACA
CTATTCAAAACAGGCCATTAAGCAGATGTATGTACTCATTCTTGGACTTGATGTTTTGGGAAATCCATTTGGCTTAATTAGAGAATTTTCTGAAGGTGTA
GAAGCATTTTTTTATGAACCTTACCAGGGAGCCATCCAGGGTCCTGAAGAGTTTGTGGAAGGAATGGCACTAGGACTTAAGGCACTAGTTGGTGGAGCTG
TTGGTGGATTGGCTGGTGCTGCCTCCAAAATCACCGGTGCTATGGCTAAGGGGGTAGCAGCTATGACCATGGATGAAGACTACCAACAGAAGAGAAGAGA
AGCCATGAATAAGCAACCAGCTGGTTTTAGAGAAGGCATCACTCGTGGAGGAAAAGGCTTAGTTTCTGGATTTGTTAGTGGCATAACAGGAATTGTTACA
AAACCAATCAAAGGAGCTCAAAAAGGAGGAGCAGCTGGTTTCTTTAAAGGTGTTGGGAAAGGTTTAGTAGGAGCGGTAGCAAGGCCAACTGGAGGCATCA
TAGACATGGCTAGCAGTACATTTCAGGGAATAAAAAGAGCTACAGAGACTTCTGAAGTGGAGAGTCTGCGACCTCCTCGGTTCTTCAATGAAGATGGAGT
TATCAGACCGTACAGGTTGAGGGATGGGACTGGAAATCAAATGTTACAGGCATCAAAAAGTTTGATATGAAAAGTTAATGCATGACTTTGCAAGTGAAAG
CCAACAGTAGATTTTAGTCTTAAAATTTACAAACTACGTACAGCTGTTTCAGTATTTTGAATACAAAGAAAACCTTTTGTATTGGTAACTTTTAATAGGA
ATTTTAATGAATCTGGTTTTTTTATAGGGTGTTCTTAGTTCTGCACTGGATTTGCTAGATTTGTTGGAAGCCTTTGTACCTTATGTATCCTCGTCATTGG
TGGTACTTACTTAACCAATTAAACCATTTCTGTTGTGGGGTTATTAAACCACTGGTAGCTTTTATACCAGATATATAATCCTTATATCCAATTACACATG
AAGAAGGAAAAGCAAAACTCAGGAACACTGCTATTGTGAATTACTCTTGGATTCTTGTGCTTTGCCTTTGAAAATGCTTAAATGGCCATGACCCTCTTCC
TGCTTTATTCTAGTGTAGTCTTTATAAAACTTGTGGGATTTGATAAGCAGTTCACATGCAAACCAGTATCTTTTAATAATACAAAGTAGCATCTGGAACA
ATAGACAGTTTGAAGTTAGAATCTGCTTAGACAACTTTCTTACTTGGTAAATTCGACTTTTTAAAACCTGGATTATGCTGTAGGTAACTAGTAATCATAT
ATAGGCTATACCAGTGTCATGTTGTTTCTGTGGTT
- refseq_VPS13A.F1 (forward primer)
- refseq_VPS13A.R1 (reverse primer)
- Single exon skipping
Frame 0
FLPLRAARPGLRRAPPPAARRLAHAS*ERPPPSLAGLARAARWASGGAAAEAAPEPVNRITSREGRG
EGGGRRSARAGCRAHHG*GTWFSSRWSWTC*TG
SWGTMWWTWTRPSSLWASGKELWPSRIFKLKKM
P*VNWMYHLKLKLVT*VILNL*FHGKTFILNLLK
PYWKKFIYL*CLLLE*NMIL*KKRNNSWKQSNR
N*KE*KKQNKK*LIKNNICRKNRTLLQKN*LHR
S*KIFR*KFPVSIFVMKMISQIGTNRCHLVFPFK
I*ACRQLINTGFHVYMMKLRNWFVS*SDWITCL
PIGM*SLRCFILVIMITPWTT*RMALSMKILFQ
KVMILYFVPYLLMPNL**IADLILTFLPPK*TWK
LSYIT*QLNLINHSISVLWSFLNQLI*WHKICH
IGSSNLMCLFTTMPENGGLMLYMAFLK*MFAPG
YGCGHGSILENIGKK*SNIKNCIKKS*QVRSHLV
NFSCLWRSWKKPWMSLI*L*LDRRQKLR*RKLD
TKFTKKE*KIQRIIKGGLAGYGLGQNKILMNSN
QMFNLKLLKKC*HLKKKLYSMKQLAIVKQQLIQL
Y*KHLKP*SFLST*KVCLLF*EKIIKNLSW*IL
**KNLAP*LCKDQEHKQ*NLKLK*IHFILLAYQ
IIQKNPASCLHWMMQCHFSKLHLR*IH*MKLFLR
GVS*KLNL*KSYMMQGQ*IV*WNSSDLQKRYI*
HSSLQQL*QNWKNFAVRQQQVYCILLKHRKFLI
SKLI*RLHILLSHKMEFLVLHQICFFWTLVI*R*
RVKVVLNYQM*NKVRPILKR*WIELMIHLIFNL
QVYSCFTVELVIIGEKHENSVYLPSIFWYPCTS
IWNCLRPWFSWM*GCPNSRFMESYLLFLYESQIK
NYKGLWN*LKAFQNLNQ*LKYLPLSNHSRFKHL
LLWEHHRFHRK*FLSWNFHLFLKMIQRRNFLMH
HVVPWKNLFSFQLELKVFEPESYKSRIVQ*I*LH
LK*DLKYQRF*SSFITLLEIVNYLW*KFLF*DW
VQKLRLEHTI*KQMPF*KSSA*NAQNTWMKTRN
QFIWLQPWITQWKTC*RWNM*RLKRMYPT*KVPI
TMFYN*LR*IFPLWIFIYTLKHF*IQ*IIFIIS
FRNQRKNQPQCPLQRLKTKEMSLKN*L*NYPQM
KISLLCRF*QNYRVYRSLFKIRNVTFLKLRLKGL
ILR*L*GLQKLK*TQS*GI*LF*ILI*QLYTKR
LFISLEKKFSASKWFLTWMQLLVLHTQI*MWLT
FRLI**LVALK*FLSRNFYILYWLL*IIFRQLNK
PWLRQLFRQLEWLLLV*KNSHKGVPEWHWILTS
KPQLWSSRSLQFLKMFLLLILD*LQ*QIPFI**
QRARALPHLLLI**Q*S*VKCDYTDLDLLMMHTR
KYWIYSCH*ILRLWLNEIYAGSGTRKFLVLM*M
LS*NQWSSFLVKKI*QLFLKHCMAIYGMKKMVV
PHLL*QKTNTVPLVELLLMLHTIQEEQLW*QLLW
*KYIHVPY*LRQH*T*ASKLMISPWCCIVQVLN
RLPLQMFVILL*NLLNLNWRIL*VL*KCIQMAQ
HFLPSH*KTVF*MIKDLMSRKQLLE**D*QLVLT
KKT*WI*STGKSEMVV*LMRSFKKCIFVQA*NF
CRLLQMSFLRPTPQALL*KPVCKHGLLRKKYLH
RNQ*SGKLMLLLKILKLCL*LT*QKMMLLL*SLQ
HNVKFAIKVTLKIVQ*LLPLKISK*EPARFFQS
REKAKSLLFCSPVTCFIKLLRKVQIHK*SICQ*
NP*H*RFHQLL*IL*LP*LQHCIQLRKPSQKKRL
LLLHIYGKRRIQRL*KCGFLKNQMKLKK*LPQL
NWYPKAR**K*TLILFL*FLRLELVIEQYLCFW
QSHVFQGKAKTGVP**ICTVSLS*KCIIIMKCLV
YGSLCLNP*KLIRLRILDHGILVSR*KRKQKWP
LLSQILKKKTTKCQNIKLSSVSIQKTN*TLHYP
NVVL*C*TI*SRHLQKLPLDLQLTS*RI*HHL*F
*IPLDLLFLFRQVILLVYSTFLWQNHMY*KMEK
V*VWIISEPRTMIISMQ*PA*AANSSSFFLHLL
TILLLIRFL*QKWDDVCTL*DTESLALKDLLFVK
LIQ*KEVRRSQFAPQCR*EIIFQSHCLFTKGIP
YWELPHLKMNSTYH*DLTDHSFF*SQKMRTIKC
VKELTLKRL*KMMVLF*RRNVDLKTLLRNHFSLI
LFQKKII*HLYQCIQKMVGIYHT*CICGHLSCS
EIFFLTKLLII*RELKIRFLL*VKDIQPRFVLH
SWVKPGYI*NYLTISITIGKVNIT*SLISKTLVL
SVLLVLQKWKRLI*ILLSI*LTILVRQLWHFIV
LIGWSIKLAACYSTKQTEFIESIHLIIKSQFSF
LFSQITFLITIRFNLW*LIVSCPISFQLILLVVM
ELLNVKA*KWTIKLVSL*T*AVLTLLEL*HLPL
FI*LKTKANTIYQWLKKEMINGSLLIWSSVSPF
GLSMLLVNFLFKSKGVKILPKGYILTSRKIVFYC
V*ITSLEVL*QK*IWPSILQLLHF*IIMMEQLH
SS**ITQRMNLFNTIKVLSVK*KIPSLLVKPCF
IHGLIRWALEG*SGDVEKAMVK*HRRMI**CL*I
WGKRQYI*FHSLKVYNALFYSLKIQGYLK*HMK
VRKQS*QSKKLQWHYKMLEFLLSTITRSKK*PI
*ALQVLMWFGKQSPRRRQDGSQ*V*STLRS*REN
LRNILNLLLQKIRLFSWTLMFRFA*PLLVIT*K
FCSRM**LYEEIIFQH*KWNITHLHINHHLEFR
FTEYRSKIRYMVLYFPLCFILLNLQSRSPWIQHQ
SPLQMSVLS*DLQDIPRYHVLSISKY*FKKWIS
G*ILGLSML*QTL*QKLR*LKIQRLSFFIKI*K
LSKKNIKQPH**INHKSASMNIFIYLLSSYI*VF
H*VPAEKKLKIQNKMED*FQFIL*IFC*RVLVP
H*QMYKM*FLSLHFLNSTISSIQHPIYSLKS*D
TIQNRPLSRCMYSFLDLMFWEIHLA*LENFLKV*
KHFFMNLTREPSRVLKSLWKEWH*DLRH*LVEL
LVDWLVLPPKSPVLWLRG*QL*PWMKTTNRREE
KP*ISNQLVLEKASLVEEKA*FLDLLVA*QELLQ
NQSKELKKEEQLVSLKVLGKV**ER*QGQLEAS
*TWLAVHFRE*KELQRLLKWRVCDLLGSSMKME
LSDRTG*GMGLEIKCYRHQKV*YEKLMHDFASES
QQ*ILVLKFTNYVQLFQYFEYKENLLYW*LLIG
ILMNLVFL*GVLSSALDLLDLLEAFVPYVSSSL
VVLT*PIKPFLLWGY*TTGSFYTRYIILISNYT*
RRKSKTQEHCYCELLLDSCALPLKMLKWP*PSS
CFILV*SL*NLWDLISSSHANQYLLIIQSSIWN
NRQFEVRICLDNFLTW*IRLFKTWIML*VTSNHI
*AIPVSCCFCG
Frame 1
SSLSGLRAQVCAALRLQPRADLRTRRESDRLRLSLGSLGLRVGPAGAPQLKPPRSR*TELPRGRGV
GKAAGGGAHGPAAVPTTAEEHGFRVGGRGRVEPV
LGGLCGGLGHVPALSGHLERSCGPQESSN*RKC
PESTGCTI*S*SWSHR*S*TYNSMEKPLYSTC*
SRIGRNLFTYSAFF*NKI*SFKRRETTHGSKATG
TEKNRRSKTKSS*SRTTSAGKTGHFCRKISYTD
HKKSSGENFQYPYSL*R*YHKSGQTAVIWYFPS
KSEHADN*SILGSMFT**N*ETGS*VNPIG*PVC
LLECEVSDVLS**L**LLGRLEEWHCQ*KYCSR
RL*FCISSHIC*CQTCDESPI*F*LFCPQNKLG
N*VT*HSN*I**TTVFQYYGAS*IS*YDGTKSAI
*EVQT*CASSPPCQRMVGLCYTWRS*SKCLPQV
MDVVMEAY*KT*AKSEAI*RTV*KKVNK*EATW
*TSRVFGGVGKNLGCL*YNYS*TDGRS*GKESWI
QNLQRRSKRSRG**RVV*LAMVLVRTKY**TAT
RCST*NS*RNVDT*RKSFTL*SNWL**NSS*SN
FTKNI*SLEVFCPLEKYVYCSKRKSSKT*AGRYC
NRRI*HLNCAKTRSTSNKI*N*NRFISYYWLTR
*FRKTPPPVFIG*CNVTFPNYI*DKSIR*NCFS
EVYHRS*TFRNHI*CKDSE*YSGILQTSKRGTSS
TAHCSNFDKTGRISQ*DSNRSTVYY*NTESS*S
QN*FEGFIYYCPTRWNF*SYIKSASFGPWSSKG
DE*KSF*ITRCETR*GQS*RDNG*SL*FI*YSTY
KCTAALQ*SW**LERSTKTQCIYPAYFGTHALQ
FGTV*GHGFHGCKDAQIQDLWKVTSYFFTNLR*
KTTRDYGID*KHSKT*TSN*SICPCQIIPDSNIY
FFGNITDFTENNSSLGTSICF*R*FRGGIF*CT
M*SLGRTSSVSNWS*KYSNQKVTKAGLFSKYDY
I*NKI*STKGFDRVLSPCWRL*TICGRNSCFRIG
CRN*D*NIRFESKCLFERVLLKMPRILG*KQET
SLFGYNPG*HNGRPVNAGICKG*KECTRLEKYL
*QCFTID*GKFFLFGYSFTH*STSEYNKLSS*YP
SAIRGKISPSVHYRD*RQRRCH*KISFKTIHK*
RYHYFADFSRIIVFTDLYSRSEM*HF*N*D*RA
*F*DDYEAFRN*NKRKAKEYNCFRF*YNSYIQKG
CLYHWKRSFQLQNGFLHGCNCWFCIHRYECG*H
SG*FNSWLH*SSFCHEISIFYIGFYR*FSGS*T
SLG*GNCSGSWNGCYWCKRTRTKEFQNGTGY*HQ
SPSCGHPAVSSF*KCFCC*FWTNYNDKYLSYDN
REPELSPTCY*FDNNKAE*NATIQISIY**CIP
GSTGSTPAIKS*GCG*TKFMLGVVPGSSLF*CKC
SAETNGVHS*SRRYNNYF*NIAWQYMV*KRW*C
LTCCNKRPIQCH*WSYY*CFTPFRRSNCGDSCC
GRSTFTCLTS*DNTKHKLQN**SHHGAV*SRS*T
GFLYRCS*SFSETC*I*IGEYYKYFKNVYRWLN
IFFLLIKKLYFR**KTSCQESNSSNDRTDSWF*
QKRHDGYKVQESQRWLCD*CGLSRNVYLCKRRIS
ADCCKCLS*GLHHRHCCRNQCANMDC*GRSTYT
GISEVGN*CYY*KS*NCVCS*HDKK*CSCFSHY
NTM*NLL*R*P*K*YNDCCH*RSPSESLPVSSSQ
EKRQNHYCFAAL*LVLSNYSERYRSTSDRYVSK
IPDTKGFTSYYKYYDYHNFSTVYN*GNHPRRNG
FFYCTFMGKEGYKDFKNVVS*RIK*N*KNSSHN*
IGTQRRDDKNEH*FYFYSS*GWNWS*NSTYASG
KVTFFRGRQKLEFPNKSALSA*ARSALL**NVW
CMGAFA*TLRN*SD*GF*TMESWYQDEKESKNGH
C*VRS*RRKLQSARI*NCHQFPFKRPIKHYIIQ
MWSCNVKQFSQGIYRSCHWIFS*LRKGSSTIYD
FKFPWTYYFCFAK*FF*CTQHSYGKIICIEKWRK
FKYGLYPNQGQ*SFQCNDQPKQQTLLHSSYTC*
PFYC**DSFNKSGTTSVHCKTQRVWR*KIYCLS
N*YSRRK*EGHNSLPSADKKSFFSPTVCLRRGYL
IGNCLT*K*IQHTIRILPIIHFSEARR*ELSNV
*RN*L*RDYKK*WCSSKEEM*I*KPF*GIISH*
YCSRKR*FNISISVFRRWLGFTIHNAFVATYPAP
KSSSLQNCLLYRGN*KFGFYSK*RTFSPDLYCT
VG*SQATFKIT*LSQSRLEK*ISHKA*SARH*F
CQFYLCYRNGKD*FRYCCPYDLQYWSDSCGIS*S
LLDGQ*NWPHVTVQSRRNSSKAST*L*KASSLF
FSAKSLF**Q*GSTYGN***VVQSVFN*YCW*S
WSC*M*RPENGLSSWCHYRPEQF*HY*NCDIYPF
LYD*KQKQIPYISG*RRK**MALS*FGAVYPLL
A*VCF**TSYSSRKE*RSSQKDIF*QAGKLYSI
ASR*RAWRYYSRSEFGRAFYSYYIFRLS*WSSYI
PLNKSHKE*TCSIQSKFSQ*NRRFPPSW*SRVL
YMG*SGGL*KAEVEM*KKPW*SNTEG*YDDAYR
FGGKDNIFSFIL*RFTTHYFIH*RSKGI*SNI*K
*ESRVSRARNCSGITRCWNFSCQQLHEARSSLY
RHYKF*CGLGNKAQEEGKMEANECKAH*EVRER
I*GIY*IFSFRR*GYSVGH*CSGSPNPYWS*HEN
SAAACNSSTKKLSSSIKSGI*HICTSIII*NSD
LQNTDPKSDTWCCISLCVLSC*TSKVGHHGFST
KALYRCQYCHEICRTFPDITY*VFQSIDSRNGSQ
VRSWVYLCFNRPYDRS*GD*KYRG*AFS*RYRS
FQRRI*NSLISRSITSQPL*IFSYISYQVTFKC
FTEFRQRRS*RFKTKWRTDSSSFFKSFAEEYWCH
TDRCTRCSF*ACIF*TQLSVPYNIRSTV*SHKT
LFKTGH*ADVCTHSWT*CFGKSIWLN*RIF*RC
RSIFL*TLPGSHPGS*RVCGRNGTRT*GTSWWSC
WWIGWCCLQNHRCYG*GGSSYDHG*RLPTEEKR
SHE*ATSWF*RRHHSWRKRLSFWIC*WHNRNCY
KTNQRSSKRRSSWFL*RCWERFSRSGSKANWRHH
RHG*QYISGNKKSYRDF*SGESATSSVLQ*RWS
YQTVQVEGWDWKSNVTGIKKFDMKS*CMTLQVK
ANSRF*S*NLQTTYSCFSILNTKKTFCIGNF**E
F**IWFFYRVFLVLHWIC*ICWKPLYLMYPRHW
WYLLNQLNHFCCGVIKPLVAFIPDI*SLYPITH
EEGKAKLRNTAIVNYSWILVLCL*KCLNGHDPLP
ALF*CSLYKTCGI**AVHMQTSIF**YKVASGT
IDSLKLESA*TTFLLGKFDFLKPGLCCR*LVII
YRLYQCHVVSVV
Frame 2
PPSQGCAPRSAPRSASSRAQTCARVVRATASVSRWAR*GCALGQRGRRS*SRPGAGEPNYLEGGAW
GRRREEERTGRLPCPPRLRNMVFESVVVDVLNR
FLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENA
LSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVE
AVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQ
ELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQI
IKNLQVKISSIHIRYEDDITNRDKPLSFGISLQ
NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLF
AYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPE
GYDFVFRPISANAKLVMNRRSDFDFSAPKINLE
IELHNIAIEFNKPQYFSIMELLESVDMMAQNLP
YRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRL
WMWSWKHIRKHRQKVKQYKELYKKKLTSKKPPG
ELLVSLEELEKTLDVFNITIARQTAEVEVKKAG
YKIYKEGVKDPEDNKGWFSWLWSWSEQNTNEQQP
DVQPETLEEMLTPEEKALLYEAIGYSETAVDPT
LLKTFEALKFFVHLKSMSIVLRENHQKPELVDI
VIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPD
NSEKPRLLSSLDDAMSLFQITFEINPLDETVSQ
RCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHL
AQLTAATLTKLEEFRSKTATGLLYIIETQKVLDL
KINLKASYIIVPQDGIFSPTSNLLLLDLGHLKV
TSKSRSELPDVKQGEANLKEIMDRAYDSFDIQL
TSVQLLYSRVGDNWREARKLSVSTQHILVPMHFN
LELSKAMVFMDVRMPKFKIYGKLPLISLRISDK
KLQGIMELIESIPKPEPVTEVSAPVKSFQIQTS
TSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAP
CSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTT
FKIRFEVPKVLIEFYHLVGDCELSVVEILVLGL
GAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKP
VYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTY
NNVLQLIKVNFSSLDIHLHTEALLNTINYLHNI
LPQSEEKSAPVSTTETEDKGDVIKKLALKLSTNE
DIITLQILAELSCLQIFIQDQKCNISEIKIEGL
DSEMIMRPSETEINAKLRNIIVLDSDITAIYKK
AVYITGKEVFSFKMVSYMDATAGSAYTDMNVVDI
QVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQ
ALAEATVQAAGMAATGVKELAQRSSRMALDINI
KAPVVVIPQSPVSENVFVADFGLITMTNTFHMIT
ESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQ
EVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVN
AQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSA
SPAVTKDQYSATSGVTTNASHHSGGATVVTAAV
VEVHSRALLVKTTLNISFKTDDLTMVLYSPGPK
QASFTDVRDPSLKLAEFKLENIISTLKMYTDGST
FSSFSLKNCILDDKRPHVKKATPRMIGLTVGFD
KKDMMDIKYRKVRDGCVTDAVFQEMYICASVEF
LQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQ
ESVKWEINVIIKNPEIVFVADMTKNDAPALVIT
TQCEICYKGNLENSTMTAAIKDLQVRACPFLPV
KRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVK
SLTLKVSPVIINTMITITSALYTTKETIPEETA
SSTAHLWEKKDTKTLKMWFLEESNETEKIAPTT
ELVPKGEMIKMNIDSIFIVLEAGIGHRTVPMLLA
KSRFSGEGKNWSSLINLHCQLELEVHYYNEMFG
VWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMA
IVESDPEEENYKVPEYKTVISFHSKDQLNITLSK
CGLVMLNNLVKAFTEAATGSSADFVKDLAPFMI
LNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGE
SLSMDYIRTKDNDHFNAMTSLSSKLFFILLTPVN
HSTADKIPLTKVGRRLYTVRHRESGVERSIVCQ
IDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDT
LLGTASPENEFNIPLGSYRSFIFLKPEDENYQMC
EGIDFEEIIKNDGALLKKKCRSKNPSKESFLIN
IVPEKDNLTSLSVYSEDGWDLPYIMHLWPPILL
RNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQ
LGKARLHLKLLDYLNHDWKSEYHIKPNQQDISF
VSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHS
PYWMVNKTGRMLQYKADGIHRKHPPNYKKPVLFS
FQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSH
GAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTP
FYMIKNKSKYHISVAEEGNDKWLSLDLEQCIPFW
PEYASSKLLIQVERSEDPPKRIYFNKQENCILL
RLDNELGGIIAEVNLAEHSTVITFLDYHDGAAT
FLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFY
TWADPVGSRRLKWRCRKSHGEVTQKDDMMMPID
LGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYE
SEKAELAEQEIAVALQDVGISLVNNYTKQEVAYI
GITSSDVVWETKPKKKARWKPMSVKHTEKLERE
FKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMK
ILQPHVIALRRNYLPALKVEYNTSAHQSSFRIQI
YRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAP
KPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDL
RLDLGFIYALTDLMTEAEVTENTEVELFHKDIEA
FKEEYKTASLVDQSQVSLYEYFHISPIKLHLSV
SLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGA
TLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRH
YSKQAIKQMYVLILGLDVLGNPFGLIREFSEGV
EAFFYEPYQGAIQGPEEFVEGMALGLKALVGGA
VGGLAGAASKITGAMAKGVAAMTMDEDYQQKRRE
AMNKQPAGFREGITRGGKGLVSGFVSGITGIVT
KPIKGAQKGGAAGFFKGVGKGLVGAVARPTGGI
IDMASSTFQGIKRATETSEVESLRPPRFFNEDGV
IRPYRLRDGTGNQMLQASKSLI*KVNA*LCK*K
PTVDFSLKIYKLRTAVSVF*IQRKPFVLVTFNR
NFNESGFFIGCS*FCTGFARFVGSLCTLCILVIG
GTYLTN*TISVVGLLNHW*LLYQIYNPYIQLHM
KKEKQNSGTLLL*ITLGFLCFAFENA*MAMTLF
LLYSSVVFIKLVGFDKQFTCKPVSFNNTK*HLEQ
*TV*S*NLLRQLSYLVNSTF*NLDYAVGN**SY
IGYTSVMLFLW
Copyright ©2008,2017, all rights reserved. 