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Sequences

Sequence NM_018399

ATGTAAAGTTTTTCCAGTGAAACAAAACGTAAGAATCTGAGTTTGTTTTTCAAAGATCACTAAATTTTAGTTATGATTATATCACATTTTCCAAAATGTG TGGCAGTTTTTGCCCTCCTTGCTCTGAGTGTTGGTGCACTGGACACTTTTATTGCTGCAGTATATGAGCATGCGGTGATATTACCAAACAGAACAGAAAC ACCTGTTTCAAAAGAAGAAGCTTTGCTCCTGATGAACAAGAACATAGATGTTTTGGAGAAAGCAGTTAAGCTGGCAGCGAAGCAGGGTGCACATATCATT GTGACCCCAGAAGATGGAATCTATGGTTGGATCTTCACCAGGGAGAGCATTTACCCCTATCTAGAGGATATACCAGACCCTGGAGTGAACTGGATTCCAT GTAGAGACCCCTGGAGATTCGGCAACACACCAGTGCAACAAAGACTCAGCTGCCTGGCCAAGGACAACTCTATCTATGTCGTGGCTAATATTGGGGACAA GAAGCCATGCAATGCCAGTGACTCTCAGTGTCCCCCTGATGGCCGTTACCAATACAACACTGATGTGGTGTTTGATTCTCAGGGAAAACTGTTGGCACGC TACCATAAGTACAATCTTTTTGCACCTGAAATTCAGTTTGATTTCCCCAAGGATTCAGAACTTGTGACTTTTGACACTCCCTTTGGGAAGTTTGGCATTT TTACTTGCTTTGACATTTTTTCTCATGACCCAGCTGTGGTGGTGGTGGATGAGTTTCAATTGACAGCATTCTCTACCCCACAGCATGGTACAACACGCTG CCCCTCCTCTCGGCTGTTCCCTTCCATTCAGCATGGGCCAAGGCCATGGGAGTCAATCTACTTGCTGCAAATACCCACAACACCAGCATGCACATGACAG GGAGTGGAATCTACGCCCCAGAAGCAGTCAAGGTGTACCACTATGACATGGAAACAGAGAGTGGTCAGCTGTTGCTATCAGAACTGAAGTCTCGGCCCCG CCGTGAGCCCACCTACCCTGCAGCTGTTGACTGGCATGCGTATGCCAGCAGTGTCAAGCCATTTTCCTCTGAACAGTCAGATTTTCTGGGGATGATTTAT TTTGATGAGTTTACCTTCACCAAGCTTAAGAGAAATACAGGAAATTACACAGCTTGCCAGAAAGATCTGTGTTGTCACTTAACTTACAAGATGTCTGAGA AGCGAACAGACGAGATCTATGCCCTAGGTGCTTTTGATGGACTGCACACAGTAGAAGGCCAATATTACTTACAGATATGTGCATTACTGAAGTGTCAAAC CACTGACCTGGAAACGTGTGGAGAACCTGTGGGGTCAGCTTTTACCAAGTTTGAAGACTTCTCCCTCAGTGGCACATTTGGAACGCGTTATGTTTTCCCA CAGATCATTCTAAGTGGGAGTCAGCTTGCCCCTGAAAGACATTATGAGATTTCAAGAGATGGACGCTTGAGGAGCCGAAGTGGAGCCCCTTTGCCTGTCT TAGTTATGGCCCTGTATGGAAGAGTGTTTGAGAAGGACCCTCCACGCTTAGGGCAGGGATCTGGGAAATTCCAGTGATCTCCTTTAGCAGAGCCCTTTTA GGATTAGCCTGGCTAAGAAAGGAAGAAAAAAAAGAGATCCGTTAGTGTCTGTTTAGAAAAGATGTTATAAACTTACAGAAACAAATATAATAAACTGAAG CAGATTTGAAAAGCAA

refseq_VNN3.F2 (forward primer)
refseq_VNN3.R2 (reverse primer)
Exon skipping and alternative donor or acceptor

Frame 0

M*SFSSETKRKNLSLFFKDH*ILVMIISHFPKC VAVFALLALSVGALDTFIAAVYEHAVILPNRTET PVSKEEALLLMNKNIDVLEKAVKLAAKQGAHII VTPEDGIYGWIFTRESIYPYLEDIPDPGVNWIP CRDPWRFGNTPVQQRLSCLAKDNSIYVVANIGDK KPCNASDSQCPPDGRYQYNTDVVFDSQGKLLAR YHKYNLFAPEIQFDFPKDSELVTFDTPFGKFGI FTCFDIFSHDPAVVVVDEFQLTAFSTPQHGTTRC PSSRLFPSIQHGPRPWESIYLLQIPTTPACT*Q GVESTPQKQSRCTTMTWKQRVVSCCYQN*SLGP AVSPPTLQLLTGMRMPAVSSHFPLNSQIFWG*FI LMSLPSPSLREIQEITQLARKICVVT*LTRCLR SEQTRSMP*VLLMDCTQ*KANITYRYVHY*SVK PLTWKRVENLWGQLLPSLKTSPSVAHLERVMFSH RSF*VGVSLPLKDIMRFQEMDA*GAEVEPLCLS *LWPCMEECLRRTLHA*GRDLGNSSDLL*QSPF RISLAKKGRKKRDPLVSV*KRCYKLTETNIIN*S RFEKQ

Frame 1

CKVFPVKQNVRI*VCFSKITKF*L*LYHIFQNV WQFLPSLL*VLVHWTLLLLQYMSMR*YYQTEQK HLFQKKKLCS**TRT*MFWRKQLSWQRSRVHISL *PQKMESMVGSSPGRAFTPI*RIYQTLE*TGFH VETPGDSATHQCNKDSAAWPRTTLSMSWLILGT RSHAMPVTLSVPLMAVTNTTLMWCLILRENCWHA TISTIFLHLKFSLISPRIQNL*LLTLPLGSLAF LLALTFFLMTQLWWWWMSFN*QHSLPHSMVQHA APPLGCSLPFSMGQGHGSQSTCCKYPQHQHAHDR EWNLRPRSSQGVPL*HGNREWSAVAIRTEVSAP P*AHLPCSC*LACVCQQCQAIFL*TVRFSGDDL F**VYLHQA*EKYRKLHSLPERSVLSLNLQDV*E ANRRDLCPRCF*WTAHSRRPILLTDMCITEVSN H*PGNVWRTCGVSFYQV*RLLPQWHIWNALCFP TDHSKWESACP*KTL*DFKRWTLEEPKWSPFACL SYGPVWKSV*EGPSTLRAGIWEIPVISFSRALL GLAWLRKEEKKEIR*CLFRKDVINLQKQI**TE ADLKS

Frame 2

VKFFQ*NKT*ESEFVFQRSLNFSYDYITFSKMC GSFCPPCSECWCTGHFYCCSI*ACGDITKQNRN TCFKRRSFAPDEQEHRCFGESS*AGSEAGCTYH CDPRRWNLWLDLHQGEHLPLSRGYTRPWSELDSM *RPLEIRQHTSATKTQLPGQGQLYLCRG*YWGQ EAMQCQ*LSVSP*WPLPIQH*CGV*FSGKTVGT LP*VQSFCT*NSV*FPQGFRTCDF*HSLWEVWHF YLL*HFFS*PSCGGGG*VSIDSILYPTAWYNTL PLLSAVPFHSAWAKAMGVNLLAANTHNTSMHMT GSGIYAPEAVKVYHYDMETESGQLLLSELKSRPR REPTYPAAVDWHAYASSVKPFSSEQSDFLGMIY FDEFTFTKLKRNTGNYTACQKDLCCHLTYKMSE KRTDEIYALGAFDGLHTVEGQYYLQICALLKCQT TDLETCGEPVGSAFTKFEDFSLSGTFGTRYVFP QIILSGSQLAPERHYEISRDGRLRSRSGAPLPV LVMALYGRVFEKDPPRLGQGSGKFQ*SPLAEPF* D*PG*ERKKKKRSVSVCLEKML*TYRNKYNKLK QI*KA

Sequence NM_078625

ATGTAAAGTTTTTCCAGTGAAACAAAACGTAAGAATCTGAGTTTGTTTTTCAAAGATCACTAAATTTTAGTTATGATTATATCACATTTTCCAAAATGTG TGGCAGTTTTTGCCCTCCTTGCTCTGAGTGTTGGTGCACTGGACACTTTTATTGCTGCAGTATATGAGCATGCGGTGATATTACCAAACAGAACAGAAAC ACCTGTTTCAAAAGAAGAAGCTTTGCTCCTGATGAACAAGAACATAGATGTTTTGGAGAAAGCAGTTAAGCTGGCAGCGAAGCAGGGTGCACATATCATT GTGACCCCAGAAGATGGAATCTATGGTTGGATCTTCACCAGGGAGAGCATTTACCCCTATCTAGAGGATATACCAGACCCTGGAGTGAACTGGATTCCAT GTAGAGACCCCTGGAGGAAGAGTAAAAAGATGAATGAGCCTGTTTCCAAAGAGCTTTGCTATCACTGTCATTCAGAATGCAATCAATATGGCCAATGGAA ATTGTATAGGACTTGAAAAAGGAAGCCCTACTTCTGGGACCACATTTTACGACCACCTAGCTGAGTGATAAATCACTAAAATATAGTAAGTTTGAGGAAA TGTCTATTGAATTAGATTCGGCAACACACCAGTGCAACAAAGACTCAGCTGCCTGGCCAAGGACAACTCTATCTATGTCGTGGCTAATATTGGGGACAAG AAGCCATGCAATGCCAGTGACTCTCAGTGTCCCCCTGATGGCCGTTACCAATACAACACTGATGTGGTGTTTGATTCTCAGGGAAAACTGTTGGCACGCT ACCATAAGTACAATCTTTTTGCACCTGAAATTCAGTTTGATTTCCCCAAGGATTCAGAACTTGTGACTTTTGACACTCCCTTTGGGAAGTTTGGCATTTT TACTTGCTTTGACATTTTTTCTCATGACCCAGCTGTGGTGGTGGTGGATGAGTTTCAATTGACAGCATTCTCTACCCCACAGCATGGTACAACACGCTGC CCCTCCTCTCGGCTGTTCCCTTCCATTCAGCATGGGCCAAGGCCATGGGAGTCAATCTACTTGCTGCAAATACCCACAACACCAGCATGCACATGACAGG GAGTGGAATCTACGCCCCAGAAGCAGTCAAGGTGTACCACTATGACATGGAAACAGAGAGTGGTCAGCTGTTGCTATCAGAACTGAAGTCTCGGCCCCGC CGTGAGCCCACCTACCCTGCAGCTGTTGACTGGCATGCGTATGCCAGCAGTGTCAAGCCATTTTCCTCTGAACAGTCAGATTTTCTGGGGATGATTTATT TTGATGAGTTTACCTTCACCAAGCTTAAGAGAAATACAGGAAATTACACAGCTTGCCAGAAAGATCTGTGTTGTCACTTAACTTACAAGATGTCTGAGAA GCGAACAGACGAGATCTATGCCCTAGGTGCTTTTGATGGACTGCACACAGTAGAAGGCCAATATTACTTACAGATATGTGCATTACTGAAGTGTCAAACC ACTGACCTGGAAACGTGTGGAGAACCTGTGGGGTCAGCTTTTACCAAGTTTGAAGACTTCTCCCTCAGTGGCACATTTGGAACGCGTTATGTTTTCCCAC AGATCATTCTAAGTGGGAGTCAGCTTGCCCCTGAAAGACATTATGAGATTTCAAGAGATGGACGCTTGAGGAGCCGAAGTGGAGCCCCTTTGCCTGTCTT AGTTATGGCCCTGTATGGAAGAGTGTTTGAGAAGGACCCTCCACGCTTAGGGCAGGGATCTGGGAAATTCCAGTGATCTCCTTTAGCAGAGCCCTTTTAG GATTAGCCTGGCTAAGAAAGGAAGAAAAAAAAGAGATCCGTTAGTGTCTGTTTAGAAAAGATGTTATAAACTTACAGAAACAAATATAATAAACTGAAGC AGATTTGAAAAGCAA

refseq_VNN3.F2 (forward primer)
refseq_VNN3.R2 (reverse primer)
Exon skipping and alternative donor or acceptor

Frame 0

M*SFSSETKRKNLSLFFKDH*ILVMIISHFPKC VAVFALLALSVGALDTFIAAVYEHAVILPNRTET PVSKEEALLLMNKNIDVLEKAVKLAAKQGAHII VTPEDGIYGWIFTRESIYPYLEDIPDPGVNWIP CRDPWRKSKKMNEPVSKELCYHCHSECNQYGQWK LYRT*KRKPYFWDHILRPPS*VINH*NIVSLRK CLLN*IRQHTSATKTQLPGQGQLYLCRG*YWGQ EAMQCQ*LSVSP*WPLPIQH*CGV*FSGKTVGTL P*VQSFCT*NSV*FPQGFRTCDF*HSLWEVWHF YLL*HFFS*PSCGGGG*VSIDSILYPTAWYNTL PLLSAVPFHSAWAKAMGVNLLAANTHNTSMHMTG SGIYAPEAVKVYHYDMETESGQLLLSELKSRPR REPTYPAAVDWHAYASSVKPFSSEQSDFLGMIY FDEFTFTKLKRNTGNYTACQKDLCCHLTYKMSEK RTDEIYALGAFDGLHTVEGQYYLQICALLKCQT TDLETCGEPVGSAFTKFEDFSLSGTFGTRYVFP QIILSGSQLAPERHYEISRDGRLRSRSGAPLPVL VMALYGRVFEKDPPRLGQGSGKFQ*SPLAEPF* D*PG*ERKKKKRSVSVCLEKML*TYRNKYNKLK QI*KA

Frame 1

CKVFPVKQNVRI*VCFSKITKF*L*LYHIFQNV WQFLPSLL*VLVHWTLLLLQYMSMR*YYQTEQK HLFQKKKLCS**TRT*MFWRKQLSWQRSRVHISL *PQKMESMVGSSPGRAFTPI*RIYQTLE*TGFH VETPGGRVKR*MSLFPKSFAITVIQNAINMANG NCIGLEKGSPTSGTTFYDHLAE**ITKI**V*GN VY*IRFGNTPVQQRLSCLAKDNSIYVVANIGDK KPCNASDSQCPPDGRYQYNTDVVFDSQGKLLAR YHKYNLFAPEIQFDFPKDSELVTFDTPFGKFGIF TCFDIFSHDPAVVVVDEFQLTAFSTPQHGTTRC PSSRLFPSIQHGPRPWESIYLLQIPTTPACT*Q GVESTPQKQSRCTTMTWKQRVVSCCYQN*SLGPA VSPPTLQLLTGMRMPAVSSHFPLNSQIFWG*FI LMSLPSPSLREIQEITQLARKICVVT*LTRCLR SEQTRSMP*VLLMDCTQ*KANITYRYVHY*SVKP LTWKRVENLWGQLLPSLKTSPSVAHLERVMFSH RSF*VGVSLPLKDIMRFQEMDA*GAEVEPLCLS *LWPCMEECLRRTLHA*GRDLGNSSDLL*QSPFR ISLAKKGRKKRDPLVSV*KRCYKLTETNIIN*S RFEKQ

Frame 2

VKFFQ*NKT*ESEFVFQRSLNFSYDYITFSKMC GSFCPPCSECWCTGHFYCCSI*ACGDITKQNRN TCFKRRSFAPDEQEHRCFGESS*AGSEAGCTYH CDPRRWNLWLDLHQGEHLPLSRGYTRPWSELDSM *RPLEEE*KDE*ACFQRALLSLSFRMQSIWPME IV*DLKKEALLLGPHFTTT*LSDKSLKYSKFEE MSIELDSATHQCNKDSAAWPRTTLSMSWLILGTR SHAMPVTLSVPLMAVTNTTLMWCLILRENCWHA TISTIFLHLKFSLISPRIQNL*LLTLPLGSLAF LLALTFFLMTQLWWWWMSFN*QHSLPHSMVQHAA PPLGCSLPFSMGQGHGSQSTCCKYPQHQHAHDR EWNLRPRSSQGVPL*HGNREWSAVAIRTEVSAP P*AHLPCSC*LACVCQQCQAIFL*TVRFSGDDLF **VYLHQA*EKYRKLHSLPERSVLSLNLQDV*E ANRRDLCPRCF*WTAHSRRPILLTDMCITEVSN H*PGNVWRTCGVSFYQV*RLLPQWHIWNALCFPT DHSKWESACP*KTL*DFKRWTLEEPKWSPFACL SYGPVWKSV*EGPSTLRAGIWEIPVISFSRALL GLAWLRKEEKKEIR*CLFRKDVINLQKQI**TEA DLKS