×
1 warning:
  • Access restricted to public data.
    Please sign in at Rnomics Platform to access your data.
Navigation
Sequences

Sequence NM_003174

TCGGCGGGAAGCGGCGATCCTGCCACCGGGAGGTGTGGAAGAGCCGGGTAGATTCTGGCTACATTGGAGATTGGTTGCTTTCTAAAACTGAAGGAGAAGC
CCATGAAGAGATGGTGGATTCTCACTGAGTTTTGACTAGCGGAAGAAAAGAGAGAGTTCAAGTGGATGGCCTTGAGGACTTGAAAAGCTGAGATATGATG
ATTTTGAAGTCATTTCACATCGAAGCCATGATTTAAATATCGGCGTTAAGATTTCAACAAGAAAAACTTAAGCTTCCTTGGATTCCCACGTCAAAGGAAA
GTTTCAAGCTTTCAGAAGGAGTTCTCACTCGAAGATAAAGAACAGCTCGCTAACCACGAAAGAGGAATCGATGCTCAGCTTTTAGTTGCACTTCCTAAAG
TTGCAGAATTAAGACAAATCTTTGAACCAAAGAAGAAAGAATTCTTAGAAATGAAAAGAAAAGAAAGAATTGCCAGGCGCCTGGAAGGGATTGAAAATGA
CACTCAGCCCATCCTCTTGCAGAGCTGCACAGGATTGGTGACTCACCGCCTGCTGGAGGAAGACACCCCTCGATACATGAGAGCCAGCGACCCTGCCAGC
CCCCACATCGGCCGATCAAATGAAGAGGAGGAAACTTCTGATTCTTCTCTAGAAAAGCAAACTCGATCCAAATACTGCACAGAAACCTCCGGTGTCCACG
GTGACTCACCCTATGGTTCGGGTACCATGGACACCCACAGTCTGGAGTCCAAAGCCGAAAGAATTGCAAGGTACAAAGCAGAAAGAAGGCGACAGCTGGC
AGAGAAGTATGGGCTGACTCTGGATCCCGAGGCCGACTCCGAGTATTTATCCCGCTATACCAAGTCCAGGAAGGAGCCTGATGCTGTCGAGAAGCGGGGA
GGAAAAAGTGACAAACAGGAAGAGTCAAGCAGAGATGCTAGTTCTCTGTACCCCGGGACCGAGACGATGGGGCTCAGGACCTGTGCCGGTGAATCCAAGG
ACTATGCCCTCCATGTGGGTGACGGCTCTTCCGACCCGGAGGTGCTGCTGAACATAGAAAACCAAAGACGAGGTCAAGAGCTGAGTGCCACCCGGCAGGC
CCATGACCTGTCCCCAGCAGCCGAGAGTTCCTCGACCTTCTCTTTCTCTGGGCGAGACTCCTCCTTCACTGAAGTGCCACGGTCCCCCAAGCACGCCCAC
AGCTCCTCCCTGCAGCAGGCAGCCTCCCGGAGCCCCTCCTTTGGTGACCCACAGCTATCCCCTGAGGCCCGACCCAGGTGCACTTCACATTCAGAAACGC
CAACTGTCGATGATGAAGAAAAGGTGGATGAACGAGCCAAGCTGAGCGTCGCCGCCAAGAGGTTGCTTTTCAGGGAGATGGAAAAATCTTTTGATGAACA
AAATGTTCCAAAGCGACGCTCAAGAAACACAGCTGTGGAGCAGAGGCTACGCCGTCTGCAGGACAGGTCCCTCACCCAGCCCATCACCACTGAAGAGGTG
GTCATCGCAGCCACATTGCAGGCCTCTGCTCACCAAAAGGCCTTAGCCAAGGACCAGACAAATGAGGGCAAAGAGCTTGCTGAGCAAGGAGAACCTGATT
CCTCCACTCTAAGCTTGGCCGAAAAGTTGGCCTTGTTTAACAAATTGTCCCAGCCAGTCTCAAAAGCGATTTCTACCCGGAACAGAATAGACACGAGACA
GAGGAGAATGAACGCTCGCTATCAAACTCAGCCAGTCACACTGGGAGAGGTGGAGCAGGTGCAGAGTGGAAAGCTCATTCCTTTCTCACCTGCCGTGAAC
ACATCAGTGTCTACCGTAGCATCCACGGTTGCTCCAATGTATGCCGGAGATCTTCGCACAAAGCCACCTCTTGACCACAATGCAAGTGCCACTGACTATA
AGTTTTCTTCTTCAATAGAAAATTCGGACTCTCCAGTTAGAAGCATTCTGAAATCGCAAGCTTGGCAGCCTTTGGTAGAGGGTAGCGAGAACAAGGGAAT
GTTGAGAGAATATGGAGAGACAGAAAGCAAGAGAGCTTTGACAGGTCGAGACAGTGGGATGGAGAAGTATGGGTCCTTTGAGGAAGCAGAAGCATCCTAC
CCCATCCTGAACCGAGCCAGGGAAGGAGACAGCCATAAGGAATCTAAATATGCTGTTCCCAGAAGAGGAAGCCTGGAACGGGCGAACCCTCCCATCACCC
ACCTCGGGGATGAACCGAAGGAATTTTCCATGGCTAAAATGAATGCACAAGGAAACTTGGACTTGAGGGACAGGCTGCCCTTTGAAGAGAAGGTGGAGGT
GGAGAATGTTATGAAAAGGAAGTTTTCACTAAGAGCGGCAGAGTTCGGGGAGCCCACTTCCGAGCAGACGGGGACAGCTGCTGGGAAAACTATTGCTCAA
ACCACAGCCCCCGTGTCCTGGAAGCCCCAGGATTCTTCGGAACAGCCACAGGAGAAGCTCTGCAAGAATCCATGTGCGATGTTTGCTGCTGGAGAGATCA
AAACGCCGACAGGGGAGGGCCTTCTTGACTCACCCAGCAAAACCATGTCTATTAAAGAAAGATTGGCACTGTTGAAGAAAAGCGGGGAGGAAGATTGGAG
AAACAGACTCAGCAGGAGGCAGGAGGGCGGCAAGGCGCCGGCCAGCAGCCTGCACACCCAGGAAGCAGGGCGGTCCCTCATCAAGAAGCGGGTCACAGAA
AGTCGAGAGAGCCAAATGACGATTGAGGAGAGGAAGCAGCTCATCACTGTGAGAGAGGAGGCCTGGAAGACGAGAGGCAGAGGAGCGGCCAACGACTCGA
CCCAGTTCACTGTGGCTGGCAGGATGGTGAAGAAAGGTTTGGCGTCACCTACTGCCATAACCCCAGTAGCCTCACCCATTTGCGGTAAAACAAGAGGCAC
CACACCCGTTTCCAAACCCCTGGAAGATATCGAAGCCAGACCAGATATGCAGTTAGAATCGGACCTGAAGTTGGACAGGCTGGAAACCTTTCTAAGAAGG
CTGAATAACAAAGTTGGCGGGATGCACGAAACGGTGCTCACTGTCACCGGCAAATCTGTGAAGGAGGTGATGAAGCCAGATGATGATGAAACCTTTGCCA
AATTTTACCGCAGCGTGGATTATAATATGCCAAGAAGTCCTGTGGAGATGGATGAGGACTTCGATGTCATTTTCGATCCTTATGCACCCAAATTGACGTC
TTCCGTGGCCGAGCACAAGCGGGCAGTTAGGCCCAAGCGCCGGGTTCAGGCCTCCAAAAACCCCCTGAAAATGCTGGCGGCAAGAGAAGATCTCCTTCAG
GAATACACTGAGCAGAGATTAAACGTTGCCTTCATGGAGTCAAAGCGGATGAAAGTAGAAAAGATGTCTTCCAACTCCAACTTCTCAGAAGTCACCCTGG
CGGGTTTAGCCAGTAAAGAAAACTTCAGCAACGTCAGCCTGCGGAGCGTCAACCTGACGGAACAGAACTCTAACAACAGCGCCGTGCCCTACAAGAGGCT
GATGCTGTTGCAGATTAAAGGAAGAAGACATGTGCAGACCAGGCTGGTGGAACCTCGAGCTTCGGCGCTCAACAGTGGGGACTGCTTCCTCCTGCTCTCT
CCCCACTGCTGCTTCCTGTGGGTAGGAGAGTTTGCAAACGTCATAGAAAAGGCGAAGGCCTCAGAACTTGCAACTTTAATTCAGACAAAGAGGGAACTTG
GTTGTAGAGCTACTTATATCCAAACCATTGAAGAAGGAATTAATACACACACTCATGCAGCCAAAGACTTCTGGAAGCTTCTGGGTGGCCAAACCAGTTA
CCAATCTGCTGGAGACCCAAAAGAAGATGAACTCTATGAAGCAGCCATAATAGAAACTAACTGCATTTACCGTCTCATGGATGACAAACTTGTTCCTGAT
GACGACTACTGGGGGAAAATTCCGAAGTGCTCCCTTCTGCAACCCAAAGAGGTACTGGTGTTTGATTTTGGTAGTGAAGTTTACGTATGGCATGGGAAAG
AAGTCACATTAGCACAACGAAAAATAGCATTTCAGCTGGCAAAGCACTTATGGAATGGAACCTTTGACTATGAGAACTGTGACATCAATCCCCTGGATCC
TGGAGAATGCAATCCGCTTATCCCCAGAAAAGGACAGGGGCGGCCCGACTGGGCGATATTTGGGAGACTTACTGAACACAATGAGACGATTTTGTTCAAA
GAGAAGTTTCTGGATTGGACGGAACTGAAGAGATCGAATGAGAAGAACCCCGGGGAACTTGCCCAGCACAAGGAAGACCCCAGGACTGATGTCAAGGCAT
ACGATGTGACACGGATGGTGTCCATGCCCCAGACGACAGCAGGCACCATCCTGGACGGAGTGAACGTCGGCCGTGGCTATGGCCTGGTGGAAGGACACGA
CAGGAGGCAGTTTGAGATCACCAGCGTTTCCGTGGATGTCTGGCACATCCTGGAATTCGACTATAGCAGGCTCCCCAAACAAAGCATCGGGCAGTTCCAT
GAGGGGGATGCCTATGTGGTCAAGTGGAAGTTCATGGTGAGCACGGCAGTGGGAAGTCGCCAGAAGGGAGAGCACTCGGTGAGGGCAGCCGGCAAAGAGA
AGTGCGTCTACTTCTTCTGGCAAGGCCGGCACTCCACCGTGAGTGAGAAGGGCACGTCGGCGCTGATGACGGTGGAGCTGGACGAGGAAAGGGGGGCCCA
GGTCCAGGTTCTCCAGGGAAAGGAGCCCCCCTGTTTCCTGCAGTGTTTCCAGGGGGGGATGGTGGTGCACTCGGGGAGGCGGGAAGAGGAAGAAGAAAAT
GTGCAAAGTGAGTGGCGGCTGTACTGCGTGCGTGGAGAGGTGCCCGTGGAAGGGAATTTGCTGGAAGTGGCCTGTCACTGTAGCAGCCTGAGGTCCAGAA
CTTCCATGGTGGTGCTTAACGTCAACAAGGCCCTCATCTACCTGTGGCACGGATGCAAAGCCCAGGCCCACACGAAGGAGGTCGGAAGGACCGCTGCGAA
CAAGATCAAGGAACAATGTCCCCTGGAAGCAGGACTGCATAGTAGCAGCAAAGTCACAATACACGAGTGTGATGAAGGCTCCGAGCCACTCGGATTCTGG
GATGCCTTAGGAAGGAGAGACAGGAAAGCCTACGATTGCATGCTTCAAGATCCTGGAAGTTTTAACTTCGCGCCCCGCCTGTTCATCCTCAGCAGCTCCT
CTGGGGATTTTGCAGCCACAGAGTTTGTGTACCCTGCCCGAGCCCCCTCTGTGGTCAGTTCCATGCCCTTCCTGCAGGAAGATCTGTACAGCGCGCCCCA
GCCAGCACTTTTCCTTGTTGACAATCACCACGAGGTGTACCTCTGGCAAGGCTGGTGGCCCATCGAGAACAAGATCACTGGTTCCGCCCGCATCCGCTGG
GCCTCCGACCGGAAGAGTGCGATGGAGACTGTGCTCCAGTACTGCAAAGGAAAAAATCTCAAGAAACCAGCCCCCAAGTCTTACCTTATCCACGCTGGTC
TGGAGCCCCTGACATTCACCAATATGTTTCCCAGCTGGGAGCACAGAGAGGACATCGCTGAGATCACAGAGATGGACACGGAAGTTTCCAATCAGATCAC
CCTCGTGGAAGACGTCTTAGCCAAGCTCTGTAAAACCATTTACCCGCTGGCCGACCTCCTGGCCAGGCCACTCCCGGAGGGGGTCGATCCTCTGAAGCTT
GAGATCTATCTCACCGACGAAGACTTCGAGTTTGCACTAGACATGACGAGGGATGAATACAACGCCCTGCCCGCCTGGAAGCAGGTGAACCTGAAGAAAG
CAAAAGGCCTGTTCTGAGTGGGGAGACGCCAGAGGAGCCTCACGGTCACGTCCAACAACACCACTGCACCAGGGAAATGGATATATATTTTTGGACTGGT
GTTTTTCACAAAGTATTTTTCAATCAGAGTTTTCAGAACCTGACATTGTTAAAGATACTGCTTGTCCCGGAGTTGTGTATTTTGTAAATGTTCAAGGGAA
CTGTTTGGAAACTTCTTTCCACCATTCAGGAGGTTATCAGAATTAATAAAAGTATCTGTTATGTGCACTTAAGCCGCAGCTGCTATAGATAGCACTGCCT
TCTTGTTCCAGCTAGGCAATGCCTTTTTTTTTTTTTTTTGAAGCAGTTCTCTTTATAAAGTGTTATTTTGATAGTTTGTGGATTCTAAAATATATATATA
TTTATATAAACACCATATAAGTCAAATATGTATTTAACAAAGCAATATGTATTCATTCACTTTCAAGATTTGTTTTGGTGTCAAAATAACATGAAAAGGT
AGATGGAGTTGCTTCTGTTGAATTAGCTCTGCCACCAATATGTATCTTCATACACGTTTGGAAATGTTTCCTGCAGCATTAGGTATGACTTGTTCTGAGT
ACTGCTTCCGGTGCTAAAATGAACAAAGAATTTGTACTTAATGGCATGGACTCTGGAGAATCTATGCGAATCAACCTTTCTACCTTAATATCTCCCCAAA
AATGTATAGTGCCTTGTTTTTATGTACAGTTTATATACAGAAAAGTTTGCTCTGCATTTTTGATGATGGTTTGGAACATTATCTACAATTTTACTCTCAA
ATAGTCAAAATAAAAACATCTCAATTTCTAATACCGGTTGTAAACAGTACACATGTCATTTTGTGATATAGGACTCCCAAATAAAAGTATCAGAATAAAC
ACAACAATTAACTGGT
  • refseq_SVIL.F1 (forward primer)
  • refseq_SVIL.R1 (reverse primer)
  • Single exon skipping

Frame 0

SAGSGDPATGRCGRAG*ILATLEIGCFLKLKEK
PMKRWWILTEF*LAEEKREFKWMALRT*KAEI**
F*SHFTSKP*FKYRR*DFNKKNLSFLGFPRQRK
VSSFQKEFSLEDKEQLANHERGIDAQLLVALPK
VAELRQIFEPKKKEFLEMKRKERIARRLEGIEND
TQPILLQSCTGLVTHRLLEEDTPRYMRASDPAS
PHIGRSNEEEETSDSSLEKQTRSKYCTETSGVH
GDSPYGSGTMDTHSLESKAERIARYKAERRRQLA
EKYGLTLDPEADSEYLSRYTKSRKEPDAVEKRG
GKSDKQEESSRDASSLYPGTETMGLRTCAGESK
DYALHVGDGSSDPEVLLNIENQRRGQELSATRQA
HDLSPAAESSSTFSFSGRDSSFTEVPRSPKHAH
SSSLQQAASRSPSFGDPQLSPEARPRCTSHSET
PTVDDEEKVDERAKLSVAAKRLLFREMEKSFDEQ
NVPKRRSRNTAVEQRLRRLQDRSLTQPITTEEV
VIAATLQASAHQKALAKDQTNEGKELAEQGEPD
SSTLSLAEKLALFNKLSQPVSKAISTRNRIDTRQ
RRMNARYQTQPVTLGEVEQVQSGKLIPFSPAVN
TSVSTVASTVAPMYAGDLRTKPPLDHNASATDY
KFSSSIENSDSPVRSILKSQAWQPLVEGSENKGM
LREYGETESKRALTGRDSGMEKYGSFEEAEASY
PILNRAREGDSHKESKYAVPRRGSLERANPPIT
HLGDEPKEFSMAKMNAQGNLDLRDRLPFEEKVEV
ENVMKRKFSLRAAEFGEPTSEQTGTAAGKTIAQ
TTAPVSWKPQDSSEQPQEKLCKNPCAMFAAGEI
KTPTGEGLLDSPSKTMSIKERLALLKKSGEEDWR
NRLSRRQEGGKAPASSLHTQEAGRSLIKKRVTE
SRESQMTIEERKQLITVREEAWKTRGRGAANDS
TQFTVAGRMVKKGLASPTAITPVASPICGKTRGT
TPVSKPLEDIEARPDMQLESDLKLDRLETFLRR
LNNKVGGMHETVLTVTGKSVKEVMKPDDDETFA
KFYRSVDYNMPRSPVEMDEDFDVIFDPYAPKLTS
SVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQ
EYTEQRLNVAFMESKRMKVEKMSSNSNFSEVTL
AGLASKENFSNVSLRSVNLTEQNSNNSAVPYKRL
MLLQIKGRRHVQTRLVEPRASALNSGDCFLLLS
PHCCFLWVGEFANVIEKAKASELATLIQTKREL
GCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY
QSAGDPKEDELYEAAIIETNCIYRLMDDKLVPD
DDYWGKIPKCSLLQPKEVLVFDFGSEVYVWHGK
EVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDP
GECNPLIPRKGQGRPDWAIFGRLTEHNETILFK
EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKA
YDVTRMVSMPQTTAGTILDGVNVGRGYGLVEGHD
RRQFEITSVSVDVWHILEFDYSRLPKQSIGQFH
EGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKE
KCVYFFWQGRHSTVSEKGTSALMTVELDEERGAQ
VQVLQGKEPPCFLQCFQGGMVVHSGRREEEEEN
VQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSR
TSMVVLNVNKALIYLWHGCKAQAHTKEVGRTAAN
KIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFW
DALGRRDRKAYDCMLQDPGSFNFAPRLFILSSS
SGDFAATEFVYPARAPSVVSSMPFLQEDLYSAPQ
PALFLVDNHHEVYLWQGWWPIENKITGSARIRW
ASDRKSAMETVLQYCKGKNLKKPAPKSYLIHAG
LEPLTFTNMFPSWEHREDIAEITEMDTEVSNQIT
LVEDVLAKLCKTIYPLADLLARPLPEGVDPLKL
EIYLTDEDFEFALDMTRDEYNALPAWKQVNLKK
AKGLF*VGRRQRSLTVTSNNTTAPGKWIYIFGLV
FFTKYFSIRVFRT*HC*RYCLSRSCVFCKCSRE
LFGNFFPPFRRLSELIKVSVMCT*AAAAIDSTA
FLFQLGNAFFFFF*SSSLYKVLF**FVDSKIYIY
LYKHHISQICI*QSNMYSFTFKICFGVKIT*KG
RWSCFC*ISSATNMYLHTRLEMFPAALGMTCSE
YCFRC*NEQRICT*WHGLWRIYANQPFYLNISPK
MYSALFLCTVYIQKSLLCIFDDGLEHYLQFYSQ
IVKIKTSQFLIPVVNSTHVIL*YRTPK*KYQNK
HNN*L

Frame 1

RREAAILPPGGVEEPGRFWLHWRLVAF*N*RRS
P*RDGGFSLSFD*RKKRESSSGWP*GLEKLRYD
DFEVISHRSHDLNIGVKISTRKT*ASLDSHVKGK
FQAFRRSSHSKIKNSSLTTKEESMLSF*LHFLK
LQN*DKSLNQRRKNS*K*KEKKELPGAWKGLKM
TLSPSSCRAAQDW*LTACWRKTPLDT*EPATLPA
PTSADQMKRRKLLILL*KSKLDPNTAQKPPVST
VTHPMVRVPWTPTVWSPKPKELQGTKQKEGDSW
QRSMG*LWIPRPTPSIYPAIPSPGRSLMLSRSGE
EKVTNRKSQAEMLVLCTPGPRRWGSGPVPVNPR
TMPSMWVTALPTRRCC*T*KTKDEVKS*VPPGR
PMTCPQQPRVPRPSLSLGETPPSLKCHGPPSTPT
APPCSRQPPGAPPLVTHSYPLRPDPGALHIQKR
QLSMMKKRWMNEPS*ASPPRGCFSGRWKNLLMN
KMFQSDAQETQLWSRGYAVCRTGPSPSPSPLKRW
SSQPHCRPLLTKRP*PRTRQMRAKSLLSKENLI
PPL*AWPKSWPCLTNCPSQSQKRFLPGTE*TRD
RGE*TLAIKLSQSHWERWSRCRVESSFLSHLP*T
HQCLP*HPRLLQCMPEIFAQSHLLTTMQVPLTI
SFLLQ*KIRTLQLEAF*NRKLGSLW*RVARTRE
C*ENMERQKAREL*QVETVGWRSMGPLRKQKHPT
PS*TEPGKETAIRNLNMLFPEEEAWNGRTLPSP
TSGMNRRNFPWLK*MHKETWT*GTGCPLKRRWR
WRML*KGSFH*ERQSSGSPLPSRRGQLLGKLLLK
PQPPCPGSPRILRNSHRRSSARIHVRCLLLERS
KRRQGRAFLTHPAKPCLLKKDWHC*RKAGRKIG
ETDSAGGRRAARRRPAACTPRKQGGPSSRSGSQK
VERAK*RLRRGSSSSL*ERRPGRREAEERPTTR
PSSLWLAGW*RKVWRHLLP*PQ*PHPFAVKQEA
PHPFPNPWKISKPDQICS*NRT*SWTGWKPF*EG
*ITKLAGCTKRCSLSPANL*RR**SQMMMKPLP
NFTAAWIIICQEVLWRWMRTSMSFSILMHPN*R
LPWPSTSGQLGPSAGFRPPKTP*KCWRQEKISFR
NTLSRD*TLPSWSQSG*K*KRCLPTPTSQKSPW
RV*PVKKTSATSACGAST*RNRTLTTAPCPTRG
*CCCRLKEEDMCRPGWWNLELRRSTVGTASSCSL
PTAASCG*ESLQTS*KRRRPQNLQL*FRQRGNL
VVELLISKPLKKELIHTLMQPKTSGSFWVAKPV
TNLLETQKKMNSMKQP**KLTAFTVSWMTNLFLM
TTTGGKFRSAPFCNPKRYWCLILVVKFTYGMGK
KSH*HNEK*HFSWQSTYGMEPLTMRTVTSIPWI
LENAIRLSPEKDRGGPTGRYLGDLLNTMRRFCSK
RSFWIGRN*RDRMRRTPGNLPSTRKTPGLMSRH
TM*HGWCPCPRRQQAPSWTE*TSAVAMAWWKDT
TGGSLRSPAFPWMSGTSWNSTIAGSPNKASGSSM
RGMPMWSSGSSW*ARQWEVARRESTR*GQPAKR
SASTSSGKAGTPP*VRRARRR**RWSWTRKGGP
RSRFSRERSPPVSCSVSRGGWWCTRGGGKRKKKM
CKVSGGCTACVERCPWKGICWKWPVTVAA*GPE
LPWWCLTSTRPSSTCGTDAKPRPTRRRSEGPLR
TRSRNNVPWKQDCIVAAKSQYTSVMKAPSHSDSG
MP*EGETGKPTIACFKILEVLTSRPACSSSAAP
LGILQPQSLCTLPEPPLWSVPCPSCRKICTARP
SQHFSLLTITTRCTSGKAGGPSRTRSLVPPASAG
PPTGRVRWRLCSSTAKEKISRNQPPSLTLSTLV
WSP*HSPICFPAGSTERTSLRSQRWTRKFPIRS
PSWKTS*PSSVKPFTRWPTSWPGHSRRGSIL*SL
RSISPTKTSSLH*T*RGMNTTPCPPGSR*T*RK
QKACSEWGDARGASRSRPTTPLHQGNGYIFLDW
CFSQSIFQSEFSEPDIVKDTACPGVVYFVNVQGN
CLETSFHHSGGYQN**KYLLCALKPQLL*IALP
SCSS*AMPFFFFFEAVLFIKCYFDSLWILKYIY
IYINTI*VKYVFNKAICIHSLSRFVLVSK*HEKV
DGVASVELALPPICIFIHVWKCFLQH*V*LVLS
TASGAKMNKEFVLNGMDSGESMRINLSTLISPQ
KCIVPCFYVQFIYRKVCSAFLMMVWNIIYNFTLK
*SK*KHLNF*YRL*TVHMSFCDIGLPNKSIRIN
TTINW

Frame 2

GGKRRSCHREVWKSRVDSGYIGDWLLSKTEGEA
HEEMVDSH*VLTSGRKERVQVDGLEDLKS*DMM
ILKSFHIEAMI*ISALRFQQEKLKLPWIPTSKE
SFKLSEGVLTRR*RTAR*PRKRNRCSAFSCTS*S
CRIKTNL*TKEERILRNEKKRKNCQAPGRD*K*
HSAHPLAELHRIGDSPPAGGRHPSIHESQRPCQ
PPHRPIK*RGGNF*FFSRKANSIQILHRNLRCPR
*LTLWFGYHGHPQSGVQSRKNCKVQSRKKATAG
REVWADSGSRGRLRVFIPLYQVQEGA*CCREAG
RKK*QTGRVKQRC*FSVPRDRDDGAQDLCR*IQG
LCPPCG*RLFRPGGAAEHRKPKTRSRAECHPAG
P*PVPSSREFLDLLFLWARLLLH*SATVPQARP
QLLPAAGSLPEPLLW*PTAIP*GPTQVHFTFRNA
NCR**RKGG*TSQAERRRQEVAFQGDGKIF**T
KCSKATLKKHSCGAEATPSAGQVPHPAHHH*RG
GHRSHIAGLCSPKGLSQGPDK*GQRAC*ARRT*F
LHSKLGRKVGLV*QIVPASLKSDFYPEQNRHET
EENERSLSNSASHTGRGGAGAEWKAHSFLTCRE
HISVYRSIHGCSNVCRRSSHKATS*PQCKCH*L*
VFFFNRKFGLSS*KHSEIASLAAFGRG*REQGN
VERIWRDRKQESFDRSRQWDGEVWVL*GSRSIL
PHPEPSQGRRQP*GI*ICCSQKRKPGTGEPSHHP
PRG*TEGIFHG*NECTRKLGLEGQAAL*REGGG
GECYEKEVFTKSGRVRGAHFRADGDSCWENYCS
NHSPRVLEAPGFFGTATGEALQESMCDVCCWRDQ
NADRGGPS*LTQQNHVY*RKIGTVEEKRGGRLE
KQTQQEAGGRQGAGQQPAHPGSRAVPHQEAGHR
KSREPNDD*GEEAAHHCERGGLEDERQRSGQRLD
PVHCGWQDGEERFGVTYCHNPSSLTHLR*NKRH
HTRFQTPGRYRSQTRYAVRIGPEVGQAGNLSKK
AE*QSWRDARNGAHCHRQICEGGDEAR***NLCQ
ILPQRGL*YAKKSCGDG*GLRCHFRSLCTQIDV
FRGRAQAGS*AQAPGSGLQKPPENAGGKRRSPS
GIH*AEIKRCLHGVKADESRKDVFQLQLLRSHPG
GFSQ*RKLQQRQPAERQPDGTEL*QQRRALQEA
DAVAD*RKKTCADQAGGTSSFGAQQWGLLPPAL
SPLLLPVGRRVCKRHRKGEGLRTCNFNSDKEGTW
L*SYLYPNH*RRN*YTHSCSQRLLEASGWPNQL
PICWRPKRR*TL*SSHNRN*LHLPSHG*QTCS*
*RLLGENSEVLPSATQRGTGV*FW**SLRMAWER
SHISTTKNSISAGKALMEWNL*L*EL*HQSPGS
WRMQSAYPQKRTGAARLGDIWETY*TQ*DDFVQ
REVSGLDGTEEIE*EEPRGTCPAQGRPQD*CQGI
RCDTDGVHAPDDSRHHPGRSERRPWLWPGGRTR
QEAV*DHQRFRGCLAHPGIRL*QAPQTKHRAVP
*GGCLCGQVEVHGEHGSGKSPEGRALGEGSRQRE
VRLLLLARPALHRE*EGHVGADDGGAGRGKGGP
GPGSPGKGAPLFPAVFPGGDGGALGEAGRGRRK
CAK*VAAVLRAWRGARGREFAGSGLSL*QPEVQN
FHGGA*RQQGPHLPVARMQSPGPHEGGRKDRCE
QDQGTMSPGSRTA**QQSHNTRV**RLRATRIL
GCLRKERQESLRLHASRSWKF*LRAPPVHPQQLL
WGFCSHRVCVPCPSPLCGQFHALPAGRSVQRAP
ASTFPC*QSPRGVPLARLVAHREQDHWFRPHPL
GLRPEECDGDCAPVLQRKKSQETSPQVLPYPRWS
GAPDIHQYVSQLGAQRGHR*DHRDGHGSFQSDH
PRGRRLSQAL*NHLPAGRPPGQATPGGGRSSEA
*DLSHRRRLRVCTRHDEG*IQRPARLEAGEPEES
KRPVLSGETPEEPHGHVQQHHCTREMDIYFWTG
VFHKVFFNQSFQNLTLLKILLVPELCIL*MFKG
TVWKLLSTIQEVIRINKSICYVHLSRSCYR*HCL
LVPARQCLFFFFLKQFSL*SVILIVCGF*NIYI
FI*TPYKSNMYLTKQYVFIHFQDLFWCQNNMKR
*MELLLLN*LCHQYVSSYTFGNVSCSIRYDLF*V
LLPVLK*TKNLYLMAWTLENLCESTFLP*YLPK
NV*CLVFMYSLYTEKFALHF**WFGTLSTILLS
NSQNKNISISNTGCKQYTCHFVI*DSQIKVSE*T
QQLTG

Sequence NM_021738

CACTGCTCTGACTGCGTCCTCCCCAGGCTGAAGTGTCCTCAGGTTTCATGTGGATTTGCCCAGTAATGGATGGCTCCACCGAGGCCAGGTTGGGGAAGTT
CAGCCTCGAGGACACTAGGGGACGAAAAACTTCAAAAAGAAGACTCTTTTTATTAATATTTTGGCGTTCTTTTTGGAGAGGAACTTTTGGGATGTAGCCT
TTACCTGTTTCCTGAATTTGACATCCAAAAAGCCTTTTGGAAAACACCATTCTAAATTTATCCTGTTCTGAATCATCATCGCTTCTGATAGATGCAGTTG
CTTGCTGACATCGTGATCTTTGATTTTGTACAACGCTATTTGGGCTAACTTTTGGGATTTTACTTTGTGCTTAGAATTTGAAAGTAGTATTCATTGGAAA
GAGACTCCAAGAAAATACTCGAAGACATCAAAAGCTGGATTCGAGGGTATAACGTGTTTTGTTTTGTTTTTTAAATTAGAAAAATAAGGAATTGCAGTGT
GATTTTCTTTCCCCCTTTAACTTAGAGGAACGAGGATTATACAGAAATTTGAAATTTCAACAAGAAAAACTTAAGCTTCCTTGGATTCCCACGTCAAAGG
AAAGTTTCAAGCTTTCAGAAGGAGTTCTCACTCGAAGATAAAGAACAGCTCGCTAACCACGAAAGAGGAATCGATGCTCAGCTTTTAGTTGCACTTCCTA
AAGTTGCAGAATTAAGACAAATCTTTGAACCAAAGAAGAAAGAATTCTTAGAAATGAAAAGAAAAGAAAGAATTGCCAGGCGCCTGGAAGGGATTGAAAA
TGACACTCAGCCCATCCTCTTGCAGAGCTGCACAGGATTGGTGACTCACCGCCTGCTGGAGGAAGACACCCCTCGATACATGAGAGCCAGCGACCCTGCC
AGCCCCCACATCGGCCGATCAAATGAAGAGGAGGAAACTTCTGATTCTTCTCTAGAAAAGCAAACTCGATCCAAATACTGCACAGAAACCTCCGGTGTCC
ACGGTGACTCACCCTATGGTTCGGGTACCATGGACACCCACAGTCTGGAGTCCAAAGCCGAAAGAATTGCAAGGTACAAAGCAGAAAGAAGGCGACAGCT
GGCAGAGAAGTATGGGCTGACTCTGGATCCCGAGGCCGACTCCGAGTATTTATCCCGCTATACCAAGTCCAGGAAGGAGCCTGATGCTGTCGAGAAGCGG
GGAGGAAAAAGTGACAAACAGGAAGAGTCAAGCAGAGATGCTAGTTCTCTGTACCCCGGGACCGAGACGATGGGGCTCAGGACCTGTGCCGGTGAATCCA
AGGACTATGCCCTCCATGTGGGTGACGGCTCTTCCGACCCGGAGGTGCTGCTGAACATAGAAAACCAAAGACGAGGTCAAGAGCTGAGTGCCACCCGGCA
GGCCCATGACCTGTCCCCAGCAGCCGAGAGTTCCTCGACCTTCTCTTTCTCTGGGCGAGACTCCTCCTTCACTGAAGTGCCACGGTCCCCCAAGCACGCC
CACAGCTCCTCCCTGCAGCAGGCAGCCTCCCGGAGCCCCTCCTTTGGTGACCCACAGCTATCCCCTGAGGCCCGACCCAGTACAGGGAAACCCAAACATG
AGTGGTTTCTCCAGAAAGATTCCGAAGGGGACACACCTTCACTTATCAACTGGCCTTCCAGAGTTAAAGTTAGAGAAAAATTGGTGAAAGAGGAAAGTGC
TCGAAACAGCCCTGAACTCGCCTCAGAGTCCGTAACTCAGAGGAGACACCAGCCAGCGCCAGTCCATTACGTGTCATTTCAGTCTGAGCACTCAGCCTTT
GATAGGGTCCCCAGCAAGGCAGCAGGCTCTACACGACAGCCAATCCGTGGCTATGTCCAACCCGCAGATACCGGTCACACCGCCAAGCTAGTGACGCCAG
AAACCCCAGAAAATGCATCTGAGTGTAGCTGGGTAGCATCAGCCACCCAGAATGTCCCCAAACCTCCCAGCTTGACGGTTCTAGAAGGTGACGGAAGGGA
TAGCCCAGTTCTCCATGTCTGCGAGTCAAAAGCAGAAGAAGAAGAAGGGGAAGGAGAAGGAGAAGAAAAAGAAGAAGATGTGTGCTTCACTGAAGCTCTC
GAGCAAAGCAAGAAAACCCTACTGGCTTTGGAGGGTGATGGGCTAGTGAGAAGCCCAGAAGATCCCTCTAGAAATGAGGACTTTGGTAAGCCTGCTGTGA
GCACAGTCACCTTAGAGCATCAGAAGGAACTGGAAAACGTGGCACAACCCCCTCAAGCTCCGCACCAGCCCACTGAGAGGACAGGCAGGAGCGAGATGGT
TCTCTACATTCAAAGTGAGCCTGTGTCCCAAGACGCCAAACCAACTGGTCACAACAGGGAAGCCTCGAAAAAGCGCAAGGTCCGTACCCGCTCTCTGTCA
GATTTCACAGGCCCCCCTCAGCTCCAGGCCTTGAAGTATAAGGACCCAGCTTCCAGGAGAGAGCTGGAGCTGCCCAGCTCCAAGACCGAAGGGCCTTATG
GGGAGATCAGCATGCTGGACACAAAAGTCTCTGTCGCCCAGCTCCGAAGTGCGTTCCTGGCATCTGCCAACGCCTGCAGGAGACCTGAACTCAAATCACG
GGTGGAGAGGTCGGCTGAAGGACCTGGCTTGCCCACCGGTGTGGAACGGGAGAGAGGGTCCCGGAAACCAAGACGCTATTTTTCTCCTGGTGAAAGTAGA
AAAACTTCCGAGAGATTTAGAACCCAACCTATAACTTCAGCAGAACGAAAGGAATCGGATAGGTGCACTTCACATTCAGAAACGCCAACTGTCGATGATG
AAGAAAAGGTGGATGAACGAGCCAAGCTGAGCGTCGCCGCCAAGAGGTTGCTTTTCAGGGAGATGGAAAAATCTTTTGATGAACAAAATGTTCCAAAGCG
ACGCTCAAGAAACACAGC
TGTGGAGCAGAGGCTACGCCGTCTGCAGGACAGGTCCCTCACCCAGCCCATCACCACTGAAGAGGTGGTCATCGCAGCCACT
GAACCTATCCCCGCTTCGTGTTCTGGGGGCACCCACCCTGTAATGGCGAGACTTCCTAGCCCCACTGTAGCTAGGAGCGCTGTGCAGCCTGCCAG
ATTGC
AGGCCTCTGCTCACCAAAAGGCCTTAGCCAAGGACCAGACAAATGAGGGCAAAGAGCTTGCTGAGCAAGGAGAACCTGATTCCTCCACTCTAAGCTTGGC
CGAAAAGTTGGCCTTGTTTAACAAATTGTCCCAGCCAGTCTCAAAAGCGATTTCTACCCGGAACAGAATAGACACGAGACAGAGGAGAATGAACGCTCGC
TATCAAACTCAGCCAGTCACACTGGGAGAGGTGGAGCAGGTGCAGAGTGGAAAGCTCATTCCTTTCTCACCTGCCGTGAACACATCAGTGTCTACCGTAG
CATCCACGGTTGCTCCAATGTATGCCGGAGATCTTCGCACAAAGCCACCTCTTGACCACAATGCAAGTGCCACTGACTATAAGTTTTCTTCTTCAATAGA
AAATTCGGACTCTCCAGTTAGAAGCATTCTGAAATCGCAAGCTTGGCAGCCTTTGGTAGAGGGTAGCGAGAACAAGGGAATGTTGAGAGAATATGGAGAG
ACAGAAAGCAAGAGAGCTTTGACAGGTCGAGACAGTGGGATGGAGAAGTATGGGTCCTTTGAGGAAGCAGAAGCATCCTACCCCATCCTGAACCGAGCCA
GGGAAGGAGACAGCCATAAGGAATCTAAATATGCTGTTCCCAGAAGAGGAAGCCTGGAACGGGCGAACCCTCCCATCACCCACCTCGGGGATGAACCGAA
GGAATTTTCCATGGCTAAAATGAATGCACAAGGAAACTTGGACTTGAGGGACAGGCTGCCCTTTGAAGAGAAGGTGGAGGTGGAGAATGTTATGAAAAGG
AAGTTTTCACTAAGAGCGGCAGAGTTCGGGGAGCCCACTTCCGAGCAGACGGGGACAGCTGCTGGGAAAACTATTGCTCAAACCACAGCCCCCGTGTCCT
GGAAGCCCCAGGATTCTTCGGAACAGCCACAGGAGAAGCTCTGCAAGAATCCATGTGCGATGTTTGCTGCTGGAGAGATCAAAACGCCGACAGGGGAGGG
CCTTCTTGACTCACCCAGCAAAACCATGTCTATTAAAGAAAGATTGGCACTGTTGAAGAAAAGCGGGGAGGAAGATTGGAGAAACAGACTCAGCAGGAGG
CAGGAGGGCGGCAAGGCGCCGGCCAGCAGCCTGCACACCCAGGAAGCAGGGCGGTCCCTCATCAAGAAGCGGGTCACAGAAAGTCGAGAGAGCCAAATGA
CGATTGAGGAGAGGAAGCAGCTCATCACTGTGAGAGAGGAGGCCTGGAAGACGAGAGGCAGAGGAGCGGCCAACGACTCGACCCAGTTCACTGTGGCTGG
CAGGATGGTGAAGAAAGGTTTGGCGTCACCTACTGCCATAACCCCAGTAGCCTCACCCATTTGCGGTAAAACAAGAGGCACCACACCCGTTTCCAAACCC
CTGGAAGATATCGAAGCCAGACCAGATATGCAGTTAGAATCGGACCTGAAGTTGGACAGGCTGGAAACCTTTCTAAGAAGGCTGAATAACAAAGTTGGCG
GGATGCACGAAACGGTGCTCACTGTCACCGGCAAATCTGTGAAGGAGGTGATGAAGCCAGATGATGATGAAACCTTTGCCAAATTTTACCGCAGCGTGGA
TTATAATATGCCAAGAAGTCCTGTGGAGATGGATGAGGACTTCGATGTCATTTTCGATCCTTATGCACCCAAATTGACGTCTTCCGTGGCCGAGCACAAG
CGGGCAGTTAGGCCCAAGCGCCGGGTTCAGGCCTCCAAAAACCCCCTGAAAATGCTGGCGGCAAGAGAAGATCTCCTTCAGGAATACACTGAGCAGAGAT
TAAACGTTGCCTTCATGGAGTCAAAGCGGATGAAAGTAGAAAAGATGTCTTCCAACTCCAACTTCTCAGAAGTCACCCTGGCGGGTTTAGCCAGTAAAGA
AAACTTCAGCAACGTCAGCCTGCGGAGCGTCAACCTGACGGAACAGAACTCTAACAACAGCGCCGTGCCCTACAAGAGGCTGATGCTGTTGCAGATTAAA
GGAAGAAGACATGTGCAGACCAGGCTGGTGGAACCTCGAGCTTCGGCGCTCAACAGTGGGGACTGCTTCCTCCTGCTCTCTCCCCACTGCTGCTTCCTGT
GGGTAGGAGAGTTTGCAAACGTCATAGAAAAGGCGAAGGCCTCAGAACTTGCAACTTTAATTCAGACAAAGAGGGAACTTGGTTGTAGAGCTACTTATAT
CCAAACCATTGAAGAAGGAATTAATACACACACTCATGCAGCCAAAGACTTCTGGAAGCTTCTGGGTGGCCAAACCAGTTACCAATCTGCTGGAGACCCA
AAAGAAGATGAACTCTATGAAGCAGCCATAATAGAAACTAACTGCATTTACCGTCTCATGGATGACAAACTTGTTCCTGATGACGACTACTGGGGGAAAA
TTCCGAAGTGCTCCCTTCTGCAACCCAAAGAGGTACTGGTGTTTGATTTTGGTAGTGAAGTTTACGTATGGCATGGGAAAGAAGTCACATTAGCACAACG
AAAAATAGCATTTCAGCTGGCAAAGCACTTATGGAATGGAACCTTTGACTATGAGAACTGTGACATCAATCCCCTGGATCCTGGAGAATGCAATCCGCTT
ATCCCCAGAAAAGGACAGGGGCGGCCCGACTGGGCGATATTTGGGAGACTTACTGAACACAATGAGACGATTTTGTTCAAAGAGAAGTTTCTGGATTGGA
CGGAACTGAAGAGATCGAATGAGAAGAACCCCGGGGAACTTGCCCAGCACAAGGAAGACCCCAGGACTGATGTCAAGGCATACGATGTGACACGGATGGT
GTCCATGCCCCAGACGACAGCAGGCACCATCCTGGACGGAGTGAACGTCGGCCGTGGCTATGGCCTGGTGGAAGGACACGACAGGAGGCAGTTTGAGATC
ACCAGCGTTTCCGTGGATGTCTGGCACATCCTGGAATTCGACTATAGCAGGCTCCCCAAACAAAGCATCGGGCAGTTCCATGAGGGGGATGCCTATGTGG
TCAAGTGGAAGTTCATGGTGAGCACGGCAGTGGGAAGTCGCCAGAAGGGAGAGCACTCGGTGAGGGCAGCCGGCAAAGAGAAGTGCGTCTACTTCTTCTG
GCAAGGCCGGCACTCCACCGTGAGTGAGAAGGGCACGTCGGCGCTGATGACGGTGGAGCTGGACGAGGAAAGGGGGGCCCAGGTCCAGGTTCTCCAGGGA
AAGGAGCCCCCCTGTTTCCTGCAGTGTTTCCAGGGGGGGATGGTGGTGCACTCGGGGAGGCGGGAAGAGGAAGAAGAAAATGTGCAAAGTGAGTGGCGGC
TGTACTGCGTGCGTGGAGAGGTGCCCGTGGAAGGGAATTTGCTGGAAGTGGCCTGTCACTGTAGCAGCCTGAGGTCCAGAACTTCCATGGTGGTGCTTAA
CGTCAACAAGGCCCTCATCTACCTGTGGCACGGATGCAAAGCCCAGGCCCACACGAAGGAGGTCGGAAGGACCGCTGCGAACAAGATCAAGGAACAATGT
CCCCTGGAAGCAGGACTGCATAGTAGCAGCAAAGTCACAATACACGAGTGTGATGAAGGCTCCGAGCCACTCGGATTCTGGGATGCCTTAGGAAGGAGAG
ACAGGAAAGCCTACGATTGCATGCTTCAAGATCCTGGAAGTTTTAACTTCGCGCCCCGCCTGTTCATCCTCAGCAGCTCCTCTGGGGATTTTGCAGCCAC
AGAGTTTGTGTACCCTGCCCGAGCCCCCTCTGTGGTCAGTTCCATGCCCTTCCTGCAGGAAGATCTGTACAGCGCGCCCCAGCCAGCACTTTTCCTTGTT
GACAATCACCACGAGGTGTACCTCTGGCAAGGCTGGTGGCCCATCGAGAACAAGATCACTGGTTCCGCCCGCATCCGCTGGGCCTCCGACCGGAAGAGTG
CGATGGAGACTGTGCTCCAGTACTGCAAAGGAAAAAATCTCAAGAAACCAGCCCCCAAGTCTTACCTTATCCACGCTGGTCTGGAGCCCCTGACATTCAC
CAATATGTTTCCCAGCTGGGAGCACAGAGAGGACATCGCTGAGATCACAGAGATGGACACGGAAGTTTCCAATCAGATCACCCTCGTGGAAGACGTCTTA
GCCAAGCTCTGTAAAACCATTTACCCGCTGGCCGACCTCCTGGCCAGGCCACTCCCGGAGGGGGTCGATCCTCTGAAGCTTGAGATCTATCTCACCGACG
AAGACTTCGAGTTTGCACTAGACATGACGAGGGATGAATACAACGCCCTGCCCGCCTGGAAGCAGGTGAACCTGAAGAAAGCAAAAGGCCTGTTCTGAGT
GGGGAGACGCCAGAGGAGCCTCACGGTCACGTCCAACAACACCACTGCACCAGGGAAATGGATATATATTTTTGGACTGGTGTTTTTCACAAAGTATTTT
TCAATCAGAGTTTTCAGAACCTGACATTGTTAAAGATACTGCTTGTCCCGGAGTTGTGTATTTTGTAAATGTTCAAGGGAACTGTTTGGAAACTTCTTTC
CACCATTCAGGAGGTTATCAGAATTAATAAAAGTATCTGTTATGTGCACTTAAGCCGCAGCTGCTATAGATAGCACTGCCTTCTTGTTCCAGCTAGGCAA
TGCCTTTTTTTTTTTTTTTTGAAGCAGTTCTCTTTATAAAGTGTTATTTTGATAGTTTGTGGATTCTAAAATATATATATATTTATATAAACACCATATA
AGTCAAATATGTATTTAACAAAGCAATATGTATTCATTCACTTTCAAGATTTGTTTTGGTGTCAAAATAACATGAAAAGGTAGATGGAGTTGCTTCTGTT
GAATTAGCTCTGCCACCAATATGTATCTTCATACACGTTTGGAAATGTTTCCTGCAGCATTAGGTATGACTTGTTCTGAGTACTGCTTCCGGTGCTAAAA
TGAACAAAGAATTTGTACTTAATGGCATGGACTCTGGAGAATCTATGCGAATCAACCTTTCTACCTTAATATCTCCCCAAAAATGTATAGTGCCTTGTTT
TTATGTACAGTTTATATACAGAAAAGTTTGCTCTGCATTTTTGATGATGGTTTGGAACATTATCTACAATTTTACTCTCAAATAGTCAAAATAAAAACAT
CTCAATTTCTAATACCGGTTGTAAACAGTACACATGTCATTTTGTGATATAGGACTCCCAAATAAAAGTATCAGAATAAACACAACAATTAACTGGT
  • refseq_SVIL.F1 (forward primer)
  • refseq_SVIL.R1 (reverse primer)
  • Single exon skipping

Frame 0

HCSDCVLPRLKCPQVSCGFAQ*WMAPPRPGWGS
SASRTLGDEKLQKEDSFY*YFGVLFGEELLGCSL
YLFPEFDIQKAFWKTPF*IYPVLNHHRF**MQL
LADIVIFDFVQRYLG*LLGFYFVLRI*K*YSLE
RDSKKILEDIKSWIRGYNVFCFVF*IRKIRNCSV
IFFPPLT*RNEDYTEI*NFNKKNLSFLGFPRQR
KVSSFQKEFSLEDKEQLANHERGIDAQLLVALP
KVAELRQIFEPKKKEFLEMKRKERIARRLEGIEN
DTQPILLQSCTGLVTHRLLEEDTPRYMRASDPA
SPHIGRSNEEEETSDSSLEKQTRSKYCTETSGV
HGDSPYGSGTMDTHSLESKAERIARYKAERRRQL
AEKYGLTLDPEADSEYLSRYTKSRKEPDAVEKR
GGKSDKQEESSRDASSLYPGTETMGLRTCAGES
KDYALHVGDGSSDPEVLLNIENQRRGQELSATRQ
AHDLSPAAESSSTFSFSGRDSSFTEVPRSPKHA
HSSSLQQAASRSPSFGDPQLSPEARPSTGKPKH
EWFLQKDSEGDTPSLINWPSRVKVREKLVKEESA
RNSPELASESVTQRRHQPAPVHYVSFQSEHSAF
DRVPSKAAGSTRQPIRGYVQPADTGHTAKLVTP
ETPENASECSWVASATQNVPKPPSLTVLEGDGRD
SPVLHVCESKAEEEEGEGEGEEKEEDVCFTEAL
EQSKKTLLALEGDGLVRSPEDPSRNEDFGKPAV
STVTLEHQKELENVAQPPQAPHQPTERTGRSEMV
LYIQSEPVSQDAKPTGHNREASKKRKVRTRSLS
DFTGPPQLQALKYKDPASRRELELPSSKTEGPY
GEISMLDTKVSVAQLRSAFLASANACRRPELKSR
VERSAEGPGLPTGVERERGSRKPRRYFSPGESR
KTSERFRTQPITSAERKESDRCTSHSETPTVDD
EEKVDERAKLSVAAKRLLFREMEKSFDEQNVPKR
RSRNTA
VEQRLRRLQDRSLTQPITTEEVVIAAT
EPIPASCSGGTHPVMARLPSPTVARSAVQPAR
L
QASAHQKALAKDQTNEGKELAEQGEPDSSTLSLA
EKLALFNKLSQPVSKAISTRNRIDTRQRRMNAR
YQTQPVTLGEVEQVQSGKLIPFSPAVNTSVSTV
ASTVAPMYAGDLRTKPPLDHNASATDYKFSSSIE
NSDSPVRSILKSQAWQPLVEGSENKGMLREYGE
TESKRALTGRDSGMEKYGSFEEAEASYPILNRA
REGDSHKESKYAVPRRGSLERANPPITHLGDEPK
EFSMAKMNAQGNLDLRDRLPFEEKVEVENVMKR
KFSLRAAEFGEPTSEQTGTAAGKTIAQTTAPVS
WKPQDSSEQPQEKLCKNPCAMFAAGEIKTPTGEG
LLDSPSKTMSIKERLALLKKSGEEDWRNRLSRR
QEGGKAPASSLHTQEAGRSLIKKRVTESRESQM
TIEERKQLITVREEAWKTRGRGAANDSTQFTVAG
RMVKKGLASPTAITPVASPICGKTRGTTPVSKP
LEDIEARPDMQLESDLKLDRLETFLRRLNNKVG
GMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVD
YNMPRSPVEMDEDFDVIFDPYAPKLTSSVAEHK
RAVRPKRRVQASKNPLKMLAAREDLLQEYTEQR
LNVAFMESKRMKVEKMSSNSNFSEVTLAGLASKE
NFSNVSLRSVNLTEQNSNNSAVPYKRLMLLQIK
GRRHVQTRLVEPRASALNSGDCFLLLSPHCCFL
WVGEFANVIEKAKASELATLIQTKRELGCRATYI
QTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDP
KEDELYEAAIIETNCIYRLMDDKLVPDDDYWGK
IPKCSLLQPKEVLVFDFGSEVYVWHGKEVTLAQR
KIAFQLAKHLWNGTFDYENCDINPLDPGECNPL
IPRKGQGRPDWAIFGRLTEHNETILFKEKFLDW
TELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMV
SMPQTTAGTILDGVNVGRGYGLVEGHDRRQFEI
TSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYV
VKWKFMVSTAVGSRQKGEHSVRAAGKEKCVYFFW
QGRHSTVSEKGTSALMTVELDEERGAQVQVLQG
KEPPCFLQCFQGGMVVHSGRREEEEENVQSEWR
LYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLN
VNKALIYLWHGCKAQAHTKEVGRTAANKIKEQC
PLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR
DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAAT
EFVYPARAPSVVSSMPFLQEDLYSAPQPALFLV
DNHHEVYLWQGWWPIENKITGSARIRWASDRKS
AMETVLQYCKGKNLKKPAPKSYLIHAGLEPLTFT
NMFPSWEHREDIAEITEMDTEVSNQITLVEDVL
AKLCKTIYPLADLLARPLPEGVDPLKLEIYLTD
EDFEFALDMTRDEYNALPAWKQVNLKKAKGLF*V
GRRQRSLTVTSNNTTAPGKWIYIFGLVFFTKYF
SIRVFRT*HC*RYCLSRSCVFCKCSRELFGNFF
PPFRRLSELIKVSVMCT*AAAAIDSTAFLFQLGN
AFFFFF*SSSLYKVLF**FVDSKIYIYLYKHHI
SQICI*QSNMYSFTFKICFGVKIT*KGRWSCFC
*ISSATNMYLHTRLEMFPAALGMTCSEYCFRC*N
EQRICT*WHGLWRIYANQPFYLNISPKMYSALF
LCTVYIQKSLLCIFDDGLEHYLQFYSQIVKIKT
SQFLIPVVNSTHVIL*YRTPK*KYQNKHNN*L

Frame 1

TALTASSPG*SVLRFHVDLPSNGWLHRGQVGEV
QPRGH*GTKNFKKKTLFINILAFFLERNFWDVA
FTCFLNLTSKKPFGKHHSKFILF*IIIASDRCSC
LLTS*SLILYNAIWANFWDFTLCLEFESSIHWK
ETPRKYSKTSKAGFEGITCFVLFFKLEK*GIAV
*FSFPL*LRGTRIIQKFEISTRKT*ASLDSHVKG
KFQAFRRSSHSKIKNSSLTTKEESMLSF*LHFL
KLQN*DKSLNQRRKNS*K*KEKKELPGAWKGLK
MTLSPSSCRAAQDW*LTACWRKTPLDT*EPATLP
APTSADQMKRRKLLILL*KSKLDPNTAQKPPVS
TVTHPMVRVPWTPTVWSPKPKELQGTKQKEGDS
WQRSMG*LWIPRPTPSIYPAIPSPGRSLMLSRSG
EEKVTNRKSQAEMLVLCTPGPRRWGSGPVPVNP
RTMPSMWVTALPTRRCC*T*KTKDEVKS*VPPG
RPMTCPQQPRVPRPSLSLGETPPSLKCHGPPSTP
TAPPCSRQPPGAPPLVTHSYPLRPDPVQGNPNM
SGFSRKIPKGTHLHLSTGLPELKLEKNW*KRKV
LETALNSPQSP*LRGDTSQRQSITCHFSLSTQPL
IGSPARQQALHDSQSVAMSNPQIPVTPPS**RQ
KPQKMHLSVAG*HQPPRMSPNLPA*RF*KVTEG
IAQFSMSASQKQKKKKGKEKEKKKKKMCASLKLS
SKARKPYWLWRVMG**EAQKIPLEMRTLVSLL*
AQSP*SIRRNWKTWHNPLKLRTSPLRGQAGARW
FSTFKVSLCPKTPNQLVTTGKPRKSARSVPALCQ
ISQAPLSSRP*SIRTQLPGESWSCPAPRPKGLM
GRSACWTQKSLSPSSEVRSWHLPTPAGDLNSNH
GWRGRLKDLACPPVWNGREGPGNQDAIFLLVKVE
KLPRDLEPNL*LQQNERNRIGALHIQKRQLSMM
KKRWMNEPS*ASPPRGCFSGRWKNLLMNKMFQS
DAQETQ
LWSRGYAVCRTGPSPSPSPLKRWSSQPL
NLSPLRVLGAPTL*WRDFLAPL*LGALCSLP
DC
RPLLTKRP*PRTRQMRAKSLLSKENLIPPL*AW
PKSWPCLTNCPSQSQKRFLPGTE*TRDRGE*TLA
IKLSQSHWERWSRCRVESSFLSHLP*THQCLP*
HPRLLQCMPEIFAQSHLLTTMQVPLTISFLLQ*
KIRTLQLEAF*NRKLGSLW*RVARTREC*ENMER
QKAREL*QVETVGWRSMGPLRKQKHPTPS*TEP
GKETAIRNLNMLFPEEEAWNGRTLPSPTSGMNR
RNFPWLK*MHKETWT*GTGCPLKRRWRWRML*KG
SFH*ERQSSGSPLPSRRGQLLGKLLLKPQPPCP
GSPRILRNSHRRSSARIHVRCLLLERSKRRQGR
AFLTHPAKPCLLKKDWHC*RKAGRKIGETDSAGG
RRAARRRPAACTPRKQGGPSSRSGSQKVERAK*
RLRRGSSSSL*ERRPGRREAEERPTTRPSSLWL
AGW*RKVWRHLLP*PQ*PHPFAVKQEAPHPFPNP
WKISKPDQICS*NRT*SWTGWKPF*EG*ITKLA
GCTKRCSLSPANL*RR**SQMMMKPLPNFTAAW
IIICQEVLWRWMRTSMSFSILMHPN*RLPWPSTS
GQLGPSAGFRPPKTP*KCWRQEKISFRNTLSRD
*TLPSWSQSG*K*KRCLPTPTSQKSPWRV*PVK
KTSATSACGAST*RNRTLTTAPCPTRG*CCCRLK
EEDMCRPGWWNLELRRSTVGTASSCSLPTAASC
G*ESLQTS*KRRRPQNLQL*FRQRGNLVVELLI
SKPLKKELIHTLMQPKTSGSFWVAKPVTNLLETQ
KKMNSMKQP**KLTAFTVSWMTNLFLMTTTGGK
FRSAPFCNPKRYWCLILVVKFTYGMGKKSH*HN
EK*HFSWQSTYGMEPLTMRTVTSIPWILENAIRL
SPEKDRGGPTGRYLGDLLNTMRRFCSKRSFWIG
RN*RDRMRRTPGNLPSTRKTPGLMSRHTM*HGW
CPCPRRQQAPSWTE*TSAVAMAWWKDTTGGSLRS
PAFPWMSGTSWNSTIAGSPNKASGSSMRGMPMW
SSGSSW*ARQWEVARRESTR*GQPAKRSASTSS
GKAGTPP*VRRARRR**RWSWTRKGGPRSRFSRE
RSPPVSCSVSRGGWWCTRGGGKRKKKMCKVSGG
CTACVERCPWKGICWKWPVTVAA*GPELPWWCL
TSTRPSSTCGTDAKPRPTRRRSEGPLRTRSRNNV
PWKQDCIVAAKSQYTSVMKAPSHSDSGMP*EGE
TGKPTIACFKILEVLTSRPACSSSAAPLGILQP
QSLCTLPEPPLWSVPCPSCRKICTARPSQHFSLL
TITTRCTSGKAGGPSRTRSLVPPASAGPPTGRV
RWRLCSSTAKEKISRNQPPSLTLSTLVWSP*HS
PICFPAGSTERTSLRSQRWTRKFPIRSPSWKTS*
PSSVKPFTRWPTSWPGHSRRGSIL*SLRSISPT
KTSSLH*T*RGMNTTPCPPGSR*T*RKQKACSE
WGDARGASRSRPTTPLHQGNGYIFLDWCFSQSIF
QSEFSEPDIVKDTACPGVVYFVNVQGNCLETSF
HHSGGYQN**KYLLCALKPQLL*IALPSCSS*A
MPFFFFFEAVLFIKCYFDSLWILKYIYIYINTI*
VKYVFNKAICIHSLSRFVLVSK*HEKVDGVASV
ELALPPICIFIHVWKCFLQH*V*LVLSTASGAK
MNKEFVLNGMDSGESMRINLSTLISPQKCIVPCF
YVQFIYRKVCSAFLMMVWNIIYNFTLK*SK*KH
LNF*YRL*TVHMSFCDIGLPNKSIRINTTINW

Frame 2

LL*LRPPQAEVSSGFMWICPVMDGSTEARLGKF
SLEDTRGRKTSKRRLFLLIFWRSFWRGTFGM*P
LPVS*I*HPKSLLENTILNLSCSESSSLLIDAV
AC*HRDL*FCTTLFGLTFGILLCA*NLKVVFIGK
RLQENTRRHQKLDSRV*RVLFCFLN*KNKELQC
DFLSPFNLEERGLYRNLKFQQEKLKLPWIPTSK
ESFKLSEGVLTRR*RTAR*PRKRNRCSAFSCTS*
SCRIKTNL*TKEERILRNEKKRKNCQAPGRD*K
*HSAHPLAELHRIGDSPPAGGRHPSIHESQRPC
QPPHRPIK*RGGNF*FFSRKANSIQILHRNLRCP
R*LTLWFGYHGHPQSGVQSRKNCKVQSRKKATA
GREVWADSGSRGRLRVFIPLYQVQEGA*CCREA
GRKK*QTGRVKQRC*FSVPRDRDDGAQDLCR*IQ
GLCPPCG*RLFRPGGAAEHRKPKTRSRAECHPA
GP*PVPSSREFLDLLFLWARLLLH*SATVPQAR
PQLLPAAGSLPEPLLW*PTAIP*GPTQYRETQT*
VVSPERFRRGHTFTYQLAFQS*S*RKIGERGKC
SKQP*TRLRVRNSEETPASASPLRVISV*ALSL
**GPQQGSRLYTTANPWLCPTRRYRSHRQASDAR
NPRKCI*V*LGSISHPECPQTSQLDGSRR*RKG
*PSSPCLRVKSRRRRRGRRRRRKRRRCVLH*SS
RAKQENPTGFGG*WASEKPRRSL*K*GLW*ACCE
HSHLRASEGTGKRGTTPSSSAPAH*EDRQERDG
SLHSK*ACVPRRQTNWSQQGSLEKAQGPYPLSV
RFHRPPSAPGLEV*GPSFQERAGAAQLQDRRALW
GDQHAGHKSLCRPAPKCVPGICQRLQET*TQIT
GGEVG*RTWLAHRCGTGERVPETKTLFFSW*K*
KNFREI*NPTYNFSRTKGIG*VHFTFRNANCR**
RKGG*TSQAERRRQEVAFQGDGKIF**TKCSKA
TLKKHS
CGAEATPSAGQVPHPAHHH*RGGHRSH
*TYPRFVFWGHPPCNGETS*PHCS*ERCAACQ
IA
GLCSPKGLSQGPDK*GQRAC*ARRT*FLHSKLG
RKVGLV*QIVPASLKSDFYPEQNRHETEENERS
LSNSASHTGRGGAGAEWKAHSFLTCREHISVYRS
IHGCSNVCRRSSHKATS*PQCKCH*L*VFFFNR
KFGLSS*KHSEIASLAAFGRG*REQGNVERIWR
DRKQESFDRSRQWDGEVWVL*GSRSILPHPEPSQ
GRRQP*GI*ICCSQKRKPGTGEPSHHPPRG*TE
GIFHG*NECTRKLGLEGQAAL*REGGGGECYEK
EVFTKSGRVRGAHFRADGDSCWENYCSNHSPRVL
EAPGFFGTATGEALQESMCDVCCWRDQNADRGG
PS*LTQQNHVY*RKIGTVEEKRGGRLEKQTQQE
AGGRQGAGQQPAHPGSRAVPHQEAGHRKSREPND
D*GEEAAHHCERGGLEDERQRSGQRLDPVHCGW
QDGEERFGVTYCHNPSSLTHLR*NKRHHTRFQT
PGRYRSQTRYAVRIGPEVGQAGNLSKKAE*QSWR
DARNGAHCHRQICEGGDEAR***NLCQILPQRG
L*YAKKSCGDG*GLRCHFRSLCTQIDVFRGRAQ
AGS*AQAPGSGLQKPPENAGGKRRSPSGIH*AEI
KRCLHGVKADESRKDVFQLQLLRSHPGGFSQ*R
KLQQRQPAERQPDGTEL*QQRRALQEADAVAD*
RKKTCADQAGGTSSFGAQQWGLLPPALSPLLLPV
GRRVCKRHRKGEGLRTCNFNSDKEGTWL*SYLY
PNH*RRN*YTHSCSQRLLEASGWPNQLPICWRP
KRR*TL*SSHNRN*LHLPSHG*QTCS**RLLGEN
SEVLPSATQRGTGV*FW**SLRMAWERSHISTT
KNSISAGKALMEWNL*L*EL*HQSPGSWRMQSA
YPQKRTGAARLGDIWETY*TQ*DDFVQREVSGLD
GTEEIE*EEPRGTCPAQGRPQD*CQGIRCDTDG
VHAPDDSRHHPGRSERRPWLWPGGRTRQEAV*D
HQRFRGCLAHPGIRL*QAPQTKHRAVP*GGCLCG
QVEVHGEHGSGKSPEGRALGEGSRQREVRLLLL
ARPALHRE*EGHVGADDGGAGRGKGGPGPGSPG
KGAPLFPAVFPGGDGGALGEAGRGRRKCAK*VAA
VLRAWRGARGREFAGSGLSL*QPEVQNFHGGA*
RQQGPHLPVARMQSPGPHEGGRKDRCEQDQGTM
SPGSRTA**QQSHNTRV**RLRATRILGCLRKER
QESLRLHASRSWKF*LRAPPVHPQQLLWGFCSH
RVCVPCPSPLCGQFHALPAGRSVQRAPASTFPC
*QSPRGVPLARLVAHREQDHWFRPHPLGLRPEEC
DGDCAPVLQRKKSQETSPQVLPYPRWSGAPDIH
QYVSQLGAQRGHR*DHRDGHGSFQSDHPRGRRL
SQAL*NHLPAGRPPGQATPGGGRSSEA*DLSHRR
RLRVCTRHDEG*IQRPARLEAGEPEESKRPVLS
GETPEEPHGHVQQHHCTREMDIYFWTGVFHKVF
FNQSFQNLTLLKILLVPELCIL*MFKGTVWKLLS
TIQEVIRINKSICYVHLSRSCYR*HCLLVPARQ
CLFFFFLKQFSL*SVILIVCGF*NIYIFI*TPY
KSNMYLTKQYVFIHFQDLFWCQNNMKR*MELLLL
N*LCHQYVSSYTFGNVSCSIRYDLF*VLLPVLK
*TKNLYLMAWTLENLCESTFLP*YLPKNV*CLV
FMYSLYTEKFALHF**WFGTLSTILLSNSQNKNI
SISNTGCKQYTCHFVI*DSQIKVSE*TQQLTG

Copyright ©2008,2017, all rights reserved.