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Sequences

Sequence NM_183247

AATCAAGCTGCCCAAAGTCCCCCAATCACTCCTGGAATACACAGAGAGAGGCAGCAGCTTGCTCAGCGGACAAGGATGCTGGGCGTGAGGGACCAAGGCC TGCCCTGCACTCGGGCCTCCTCCAGCCAGTGCTGACCAGGGACTTCTGACCTGCTGGCCAGCCAGGACCTGTGTGGGGAGGCCCTCCTGCTGCCTTGGGG TGACAATCTCAGCTCCAGGCTACAGGGAGACCGGGAGGATCACAGAGCCAGCATGGATCCTGACAGTGATCAACCTCTGAACAGCCTCGATGTCAAACCC CTGCGCAAACCCCGTATCCCCATGGAGACCTTCAGAAAGGTGGGGATCCCCATCATCATAGCACTACTGAGCCTGGCGAGTATCATCATTGTGGTTGTCC TCATCAAGGTGATTCTGGATAAATACTACTTCCTCTGCGGGCAGCCTCTCCACTTCATCCCGAGGAAGCAGCTGTGTGACGGAGAGCTGGACTGTCCCTT GGGGGAGGACGAGGAGCACTGTGTCAAGAGCTTCCCCGAAGGGCCTGCAGTGGCAGTCCGCCTCTCCAAGGACCGATCCACACTGCAGGTGCTGGACTCG GCCACAGGGAACTGGTTCTCTGCCTGTTTCGACAACTTCACAGAAGCTCTCGCTGAGACAGCCTGTAGGCAGATGGGCTACAGCAGCAAACCCACTTTCA GAGCTGTGGAGATTGGCCCAGACCAGGATCTGGATGTTGTTGAAATCACAGAAAACAGCCAGGAGCTTCGCATGCGGAACTCAAGTGGGCCCTGTCTCTC AGGCTCCCTGGTCTCCCTGCACTGTCTTGCCTGTGGGAAGAGCCTGAAGACCCCCCGTGTGGTGGGTGTGGAGGAGGCCTCTGTGGATTCTTGGCCTTGG CAGGTCAGCATCCAGTACGACAAACAGCACGTCTGTGGAGGGAGCATCCTGGACCCCCACTGGGTCCTCACGGCAGCCCACTGCTTCAGGAAACATACCG ATGTGTTCAACTGGAAGGTGCGGGCAGGCTCAGACAAACTGGGCAGCTTCCCATCCCTGGCTGTGGCCAAGATCATCATCATTGAATTCAACCCCATGTA CCCCAAAGACAATGACATCGCCCTCATGAAGCTGCAGTTCCCACTCACTTTCTCAGGCACAGTCAGGCCCATCTGTCTGCCCTTCTTTGATGAGGAGCTC ACTCCAGCCACCCCACTCTGGATCATTGGATGGGGCTTTACGAAGCAGAATGGAGGGTGACAGTGGTGGGCCCCTGATGTACCAATCTGACCAGTGGCAT GTGGTGGGCATCGTTAGTTGGGGCTATGGCTGCGGGGGCCCGAGCACCCCAGGAGTATACACCAAGGTCTCAGCCTATCTCAACTGGATCTACAATGTCT GGAAGGCTGAGCTGTAATGCTGCTGCCCCTTTGCAGTGCTGGGAGCCGCTTCCTTCCTGCCCTGCCCACCTGGGGATCCCCCAAAGTCAGACACAGAGCA AGAGTCCCCTTGGGTACACCCCTCTGCCCACAGCCTCAGCATTTCTTGGAGCAGCAAAGGGCCTCAATTCCTATAAGAGACCCTCGCAGCCCAGAGGCGC CCAGAGGAAGTCAGCAGCCCTAGCTCGGCCACACTTGGTGCTCCCAGCATCCCAGGGAGAGACACAGCCCACTGAACAAGGTCTCAGGGGTATTGCTAAG CCAAGAAGGAACTTTCCCACACTACTGAATGGAAGCAGGCTGTCTTGTAAAAGCCCAGATCACTGTGGGCTGGAGAGGAGAAGGAAAGGGTCTGCGCCAG CCCTGTCCGTCTTCACCCATCCCCAAGCCTACTAGAGCAAGAAACCAGTTGTAATATAAAATGCACTGCCCTACTGTTGGTATGACTACCGTTACCTACT GTTGTCATTGTTATTACAGCTATGGCCACTATTATTAAAGAGCTGTGTAACATCTCTGG

refseq_TMPRSS4.F1 (forward primer)
refseq_TMPRSS4.R1 (reverse primer)
Single exon skipping

Frame 0

NQAAQSPPITPGIHRERQQLAQRTRMLGVRDQG LPCTRASSSQC*PGTSDLLASQDLCGEALLLPWG DNLSSRLQGDREDHRASMDPDSDQPLNSLDVKP LRKPRIPMETFRKVGIPIIIALLSLASIIIVVV LIKVILDKYYFLCGQPLHFIPRKQLCDGELDCPL GEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDS ATGNWFSACFDNFTEALAETACRQMGYSSKPTF RAVEIGPDQDLDVVEITENSQELRMRNSSGPCLS GSLVSLHCLACGKSLKTPRVVGVEEASVDSWPW QVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHT DVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMY PKDNDIALMKLQFPLTFSGTVRPICLPFFDEEL TPATPLWIIGWGFTKQNGG*QWWAPDVPI*PVA CGGHR*LGLWLRGPEHPRSIHQGLSLSQLDLQCL EG*AVMLLPLCSAGSRFLPALPTWGSPKVRHRA RVPLGTPLCPQPQHFLEQQRASIPIRDPRSPEA PRGSQQP*LGHTWCSQHPRERHSPLNKVSGVLLS QEGTFPHY*MEAGCLVKAQITVGWRGEGKGLRQ PCPSSPIPKPTRARNQL*YKMHCPTVGMTTVTY CCHCYYSYGHYY*RAV*HLW

Frame 1

IKLPKVPQSLLEYTERGSSLLSGQGCWA*GTKA CPALGPPPASADQGLLTCWPARTCVGRPSCCLG VTISAPGYRETGRITEPAWILTVINL*TASMSNP CANPVSPWRPSERWGSPSS*HY*AWRVSSLWLS SSR*FWINTTSSAGSLSTSSRGSSCVTESWTVP WGRTRSTVSRASPKGLQWQSASPRTDPHCRCWTR PQGTGSLPVSTTSQKLSLRQPVGRWATAANPLS ELWRLAQTRIWMLLKSQKTARSFACGTQVGPVS QAPWSPCTVLPVGRA*RPPVWWVWRRPLWILGLG RSASSTTNSTSVEGASWTPTGSSRQPTASGNIP MCSTGRCGQAQTNWAASHPWLWPRSSSLNSTPC TPKTMTSPS*SCSSHSLSQAQSGPSVCPSLMRSS LQPPHSGSLDGALRSRMEGDSGGPLMYQSDQWH VVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNV WKAEL*CCCPFAVLGAASFLPCPPGDPPKSDTEQ ESPWVHPSAHSLSISWSSKGPQFL*ETLAAQRR PEEVSSPSSATLGAPSIPGRDTAH*TRSQGYC* AKKELSHTTEWKQAVL*KPRSLWAGEEKERVCAS PVRLHPSPSLLEQETSCNIKCTALLLV*LPLPT VVIVITAMATIIKELCNIS

Frame 2

SSCPKSPNHSWNTQREAAACSADKDAGREGPRP ALHSGLLQPVLTRDF*PAGQPGPVWGGPPAALG *QSQLQATGRPGGSQSQHGS*Q*STSEQPRCQT PAQTPYPHGDLQKGGDPHHHSTTEPGEYHHCGCP HQGDSG*ILLPLRAASPLHPEEAAV*RRAGLSL GGGRGALCQELPRRACSGSPPLQGPIHTAGAGL GHRELVLCLFRQLHRSSR*DSL*ADGLQQQTHFQ SCGDWPRPGSGCC*NHRKQPGASHAELKWALSL RLPGLPALSCLWEEPEDPPCGGCGGGLCGFLAL AGQHPVRQTARLWREHPGPPLGPHGSPLLQETYR CVQLEGAGRLRQTGQLPIPGCGQDHHH*IQPHV PQRQ*HRPHEAAVPTHFLRHSQAHLSALL**GA HSSHPTLDHWMGLYEAEWRVTVVGP*CTNLTSGM WWASLVGAMAAGARAPQEYTPRSQPISTGSTMS GRLSCNAAAPLQCWEPLPSCPAHLGIPQSQTQS KSPLGYTPLPTASAFLGAAKGLNSYKRPSQPRGA QRKSAALARPHLVLPASQGETQPTEQGLRGIAK PRRNFPTLLNGSRLSCKSPDHCGLERRRKGSAP ALSVFTHPQAY*SKKPVVI*NALPYCWYDYRYLL LSLLLQLWPLLLKSCVTSL

Sequence NM_019894

AATCAAGCTGCCCAAAGTCCCCCAATCACTCCTGGAATACACAGAGAGAGGCAGCAGCTTGCTCAGCGGACAAGGATGCTGGGCGTGAGGGACCAAGGCC TGCCCTGCACTCGGGCCTCCTCCAGCCAGTGCTGACCAGGGACTTCTGACCTGCTGGCCAGCCAGGACCTGTGTGGGGAGGCCCTCCTGCTGCCTTGGGG TGACAATCTCAGCTCCAGGCTACAGGGAGACCGGGAGGATCACAGAGCCAGCATGTTACAGGATCCTGACAGTGATCAACCTCTGAACAGCCTCGATGTC AAACCCCTGCGCAAACCCCGTATCCCCATGGAGACCTTCAGAAAGGTGGGGATCCCCATCATCATAGCACTACTGAGCCTGGCGAGTATCATCATTGTGG TTGTCCTCATCAAGGTGATTCTGGATAAATACTACTTCCTCTGCGGGCAGCCTCTCCACTTCATCCCGAGGAAGCAGCTGTGTGACGGAGAGCTGGACTG TCCCTTGGGGGAGGACGAGGAGCACTGTGTCAAGAGCTTCCCCGAAGGGCCTGCAGTGGCAGTCCGCCTCTCCAAGGACCGATCCACACTGCAGGTGCTG GACTCGGCCACAGGGAACTGGTTCTCTGCCTGTTTCGACAACTTCACAGAAGCTCTCGCTGAGACAGCCTGTAGGCAGATGGGCTACAGCAGCAAACCCA CTTTCAGAGCTGTGGAGATTGGCCCAGACCAGGATCTGGATGTTGTTGAAATCACAGAAAACAGCCAGGAGCTTCGCATGCGGAACTCAAGTGGGCCCTG TCTCTCAGGCTCCCTGGTCTCCCTGCACTGTCTTGCCTGTGGGAAGAGCCTGAAGACCCCCCGTGTGGTGGGTGTGGAGGAGGCCTCTGTGGATTCTTGG CCTTGGCAGGTCAGCATCCAGTACGACAAACAGCACGTCTGTGGAGGGAGCATCCTGGACCCCCACTGGGTCCTCACGGCAGCCCACTGCTTCAGGAAAC ATACCGATGTGTTCAACTGGAAGGTGCGGGCAGGCTCAGACAAACTGGGCAGCTTCCCATCCCTGGCTGTGGCCAAGATCATCATCATTGAATTCAACCC CATGTACCCCAAAGACAATGACATCGCCCTCATGAAGCTGCAGTTCCCACTCACTTTCTCAGGCACAGTCAGGCCCATCTGTCTGCCCTTCTTTGATGAG GAGCTCACTCCAGCCACCCCACTCTGGATCATTGGATGGGGCTTTACGAAGCAGAATGGAGGGAAGATGTCTGACATACTGCTGCAGGCGTCAGTCCAGG TCATTGACAGCACACGGTGCAATGCAGACGATGCGTACCAGGGGGAAGTCACCGAGAAGATGATGTGTGCAGGCATCCCGGAAGGGGGTGTGGACACCTG CCAGGGTGACAGTGGTGGGCCCCTGATGTACCAATCTGACCAGTGGCATGTGGTGGGCATCGTTAGTTGGGGCTATGGCTGCGGGGGCCCGAGCACCCCA GGAGTATACACCAAGGTCTCAGCCTATCTCAACTGGATCTACAATGTCTGGAAGGCTGAGCTGTAATGCTGCTGCCCCTTTGCAGTGCTGGGAGCCGCTT CCTTCCTGCCCTGCCCACCTGGGGATCCCCCAAAGTCAGACACAGAGCAAGAGTCCCCTTGGGTACACCCCTCTGCCCACAGCCTCAGCATTTCTTGGAG CAGCAAAGGGCCTCAATTCCTATAAGAGACCCTCGCAGCCCAGAGGCGCCCAGAGGAAGTCAGCAGCCCTAGCTCGGCCACACTTGGTGCTCCCAGCATC CCAGGGAGAGACACAGCCCACTGAACAAGGTCTCAGGGGTATTGCTAAGCCAAGAAGGAACTTTCCCACACTACTGAATGGAAGCAGGCTGTCTTGTAAA AGCCCAGATCACTGTGGGCTGGAGAGGAGAAGGAAAGGGTCTGCGCCAGCCCTGTCCGTCTTCACCCATCCCCAAGCCTACTAGAGCAAGAAACCAGTTG TAATATAAAATGCACTGCCCTACTGTTGGTATGACTACCGTTACCTACTGTTGTCATTGTTATTACAGCTATGGCCACTATTATTAAAGAGCTGTGTAAC ATCTCTGG

refseq_TMPRSS4.F1 (forward primer)
refseq_TMPRSS4.R1 (reverse primer)
Single exon skipping

Frame 0

NQAAQSPPITPGIHRERQQLAQRTRMLGVRDQG LPCTRASSSQC*PGTSDLLASQDLCGEALLLPWG DNLSSRLQGDREDHRASMLQDPDSDQPLNSLDV KPLRKPRIPMETFRKVGIPIIIALLSLASIIIV VVLIKVILDKYYFLCGQPLHFIPRKQLCDGELDC PLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVL DSATGNWFSACFDNFTEALAETACRQMGYSSKP TFRAVEIGPDQDLDVVEITENSQELRMRNSSGPC LSGSLVSLHCLACGKSLKTPRVVGVEEASVDSW PWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRK HTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNP MYPKDNDIALMKLQFPLTFSGTVRPICLPFFDE ELTPATPLWIIGWGFTKQNGGKMSDILLQASVQ VIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTC QGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTP GVYTKVSAYLNWIYNVWKAEL*CCCPFAVLGAA SFLPCPPGDPPKSDTEQESPWVHPSAHSLSISWS SKGPQFL*ETLAAQRRPEEVSSPSSATLGAPSI PGRDTAH*TRSQGYC*AKKELSHTTEWKQAVL* KPRSLWAGEEKERVCASPVRLHPSPSLLEQETSC NIKCTALLLV*LPLPTVVIVITAMATIIKELCN IS

Frame 1

IKLPKVPQSLLEYTERGSSLLSGQGCWA*GTKA CPALGPPPASADQGLLTCWPARTCVGRPSCCLG VTISAPGYRETGRITEPACYRILTVINL*TASMS NPCANPVSPWRPSERWGSPSS*HY*AWRVSSLW LSSSR*FWINTTSSAGSLSTSSRGSSCVTESWT VPWGRTRSTVSRASPKGLQWQSASPRTDPHCRCW TRPQGTGSLPVSTTSQKLSLRQPVGRWATAANP LSELWRLAQTRIWMLLKSQKTARSFACGTQVGP VSQAPWSPCTVLPVGRA*RPPVWWVWRRPLWILG LGRSASSTTNSTSVEGASWTPTGSSRQPTASGN IPMCSTGRCGQAQTNWAASHPWLWPRSSSLNST PCTPKTMTSPS*SCSSHSLSQAQSGPSVCPSLMR SSLQPPHSGSLDGALRSRMEGRCLTYCCRRQSR SLTAHGAMQTMRTRGKSPRR*CVQASRKGVWTP ARVTVVGP*CTNLTSGMWWASLVGAMAAGARAPQ EYTPRSQPISTGSTMSGRLSCNAAAPLQCWEPL PSCPAHLGIPQSQTQSKSPLGYTPLPTASAFLG AAKGLNSYKRPSQPRGAQRKSAALARPHLVLPAS QGETQPTEQGLRGIAKPRRNFPTLLNGSRLSCK SPDHCGLERRRKGSAPALSVFTHPQAY*SKKPV VI*NALPYCWYDYRYLLLSLLLQLWPLLLKSCVT SL

Frame 2

SSCPKSPNHSWNTQREAAACSADKDAGREGPRP ALHSGLLQPVLTRDF*PAGQPGPVWGGPPAALG *QSQLQATGRPGGSQSQHVTGS*Q*STSEQPRC QTPAQTPYPHGDLQKGGDPHHHSTTEPGEYHHCG CPHQGDSG*ILLPLRAASPLHPEEAAV*RRAGL SLGGGRGALCQELPRRACSGSPPLQGPIHTAGA GLGHRELVLCLFRQLHRSSR*DSL*ADGLQQQTH FQSCGDWPRPGSGCC*NHRKQPGASHAELKWAL SLRLPGLPALSCLWEEPEDPPCGGCGGGLCGFL ALAGQHPVRQTARLWREHPGPPLGPHGSPLLQET YRCVQLEGAGRLRQTGQLPIPGCGQDHHH*IQP HVPQRQ*HRPHEAAVPTHFLRHSQAHLSALL** GAHSSHPTLDHWMGLYEAEWREDV*HTAAGVSPG H*QHTVQCRRCVPGGSHREDDVCRHPGRGCGHL PG*QWWAPDVPI*PVACGGHR*LGLWLRGPEHP RSIHQGLSLSQLDLQCLEG*AVMLLPLCSAGSRF LPALPTWGSPKVRHRARVPLGTPLCPQPQHFLE QQRASIPIRDPRSPEAPRGSQQP*LGHTWCSQH PRERHSPLNKVSGVLLSQEGTFPHY*MEAGCLVK AQITVGWRGEGKGLRQPCPSSPIPKPTRARNQL *YKMHCPTVGMTTVTYCCHCYYSYGHYY*RAV* HLW