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Sequences

Sequence NM_033207

AATGTGGACTCCCGTCAGCTGGGGATGGAGTGGCCAGCCTCAGCCTCATGTAACCCATTGTTTCCAAAGGGCTGCAGGCTGCAGAAGCCCCCAAGCTCTC AGGCCAGCTGTGGCTTCTTTGCTGAGATGGAGGTATAGCCAAGAAAGCAGCCTGAAAAGTAAGGACAGAAAATCAAGGCAAAGAGGGTGGGTGAACCAGG CCATACACGTCGGCCATGCAGCAGCAGCCCATCTTTCCCGAGGGATGGACTGAGGGCTTGGCTACTCCCCTGACCATAAATGGCTTGGCCAGGGTTCTCT TGGAGCCACCTCTCAGCCTGCCTCTGCAGCTTTGTCAGTTAACTGTTCCTACAAATGAAAGACACAAGCCAATAAAGCCAGTGAGAAAGGAGCTTACCAA AGGCAGTGTACGAAGAAGGTTCCTGGGAGACTGTCAGAAATGAGTTTTTCACTGAACTTCACCCTGCCGGCGAACACAACGTCCTCTCCTGTCACAGGTG GGAAAGAAACGGACTGTGGGCCCTCTCTTGGATTAGCGGCGGGCATACCATTGCTGGTGGCCACAGCCCTGCTGGTGGCTTTACTATTTACTTTGATTCA CCGAAGAAGAAGCAGCATTGAGGCCATGGAGGAAAGTGACAGACCATGTGAAATTTCAGAAATTGATGACAATCCCAAGATATCTGAGAATCCTAGGAGA TCACCCACACATGAGAAGAATACGATGGGAGCACAAGAGGCCCACATATATGTGAAGACTGTAGCAGGAAGCGAGGAACCTGTGCATGACCGTTACCGTC CTACTATAGAAATGGAAAGAAGGAGGGGATTGTGGTGGCTTGTGCCCAGACTGAGCCTGGAATGATGCAGCTCAGTCAAGGAGCAGCAGACCTGGCACTG GAACAGGGTTGAAAACCCAGGGTTTTGTACTTGGAGAGGAAAGATGCCAAGCTGCTTCTTAATCAATCCAAATTTCATTTACAGCTCTGGAACACTTTGG GGCTGATTTGTCTCTTTAGGGGACATCCCCAACATGGTTAATTCCAACTCTCAGATCTTGTGCTTTAGTTAGTACATGTGACTCACCAGATGGGGTCCTT AGATCCTATTCCTGCTCCCAGTGGGAATTTGCTTTTCTTTGTCATTTTGGGAAAGGGGCTTGGTTTCTGAGTGTCTTGCCTTCTCATCTTTTTTTTTCAT ATCCTTTTTCTCAAAAAAGCCATCAGATCTGACTTTCATGGAAGTGTTGCTGAGGTCAGCCTGGTGCAAGTTGGGATACAAATGAAACTTATGCAGGATG TGTGAGAGGAAGCAGTTAATTGTTTCTGAATATCTCAGGGTAGGAACCATGTGGAGCCACACATTCCCTGACCACAGGGAAGCACCTGGCTCAATCATGT CACACAGCAGTGGAAAGAATACGGACTCTTAAGTCACACCTACCACTGAGCAGCTGTACGACTTTGGAGAAGTTGTTTAACATTTTCAAGCCTCAGTTTT TGCTTTTTTAAAGGAGGGGAAATATTTGCCTCATGTCATAATTGAAAAGATTAAATAAGAAATAAAGGGAAGTGTCTGCTACTTAGTTGCCAGTCAAAAT GTTAGTTCTCTCTCTCTACCACCTTCTTCCTACCTCTTCCCATATTGCTTGCCTGATAAAACAGCTAATCACCAGCATTTGTTCCCCATAGTCACAGGGC CACACAAGGGAACATTTAGGACAAACTTTCTCCATGGCCTATGATCCAAATTGTTATCTAAAGATGATTCTAGGTGTTGCTGGTAGTATGTGAATCTTCC AATCTAGGTGTGATCGTGTCCTCATATGAATCAGGAAAAGGCAGTTTCTTACAAGTTCCGAATTCCAAATACAGAGACTGGTGGTGTTACATTTAACCTT AAAGATGTTAATGTTGATGGAAATTCATGTTTCATATTAAAACAACACTTTGTCTTTACAATGAAACATTTTGCTTAATTTTTAAAGTAAGACATTATGA TACCTCTGATGGCAGTTCCTCAAATAACTTTAACTTTTGTGCTTTAGGGATAGTTGTTAAAGTTACAACTTCTTTTATTTTATTTTTTAAAGGCTTCAGA TTAAACAAGAGCCCTTAAGCCCACGCATAGCATTGCCGCTTCAGCTTGCTGAGGACTGTCTCCAAGGAGGCCAAATGGAAAAGGAGAGGCTACTTCAAGT GGTGTTGGCCCATTGAGCCTATTGGGCAAACTATAACCAGGTTGCCTTATTTTGGGTGGATTACTCCAGGAGAGGCCACCCTCCAGCTTTCTCTTATCCC AGTAACTCCTCTTCCCATTTTCCAATCCATCCCCAGCCTTTTTTTTTTTTCTTCTGTACTCTTCTTTTGCCTTCAATATGAGTTTCATTTCCTCTGTGTC TTTGGGCAGACTTCCTTCTAACATGTGTCAGCTACCCTACCACACACCTGGCCTAGGAGACACATCATTCATTGCTCCTACTTGTGTCTGTAATCAGAGA GTATTTAAGGAGGGCAGTTCTGCGACGGACTGTGTGTGTGTTGAAAGTAAAGATGGGGGGCCGCGGGGAAGGCAAGAGTTTTTCCAAAAGATTATTAGAA ATGAGGGCTGTATCTACTCTGTGGAGTAGAACCAAGTCTACTTGGAGAAAAGAACCAAGTCCTTGGATATCTAGGGGAAAGCTGTTTGGCAGAAAGAAAA ATCAAGAGGACCCAAGGGGATGGAGACAGGACCACAGGAATGGGCCAAGGAGCAACGTGCCTGCCATTCAGCCAGCTTGGGACAGGCTTTCACTTTCACT CCCATGAGGAGGCTTCCAGGCAGCCTGGTTCCCCCATGTATAGCCATTGCCCTCTAGCAGGCCAGGCCTCCCAGTGGGAAGGCCTGGGTCCAGGGCATCT TAAGTTCATCCAGCAGCTCCATGAGCCACACAGATATCCTAGAAAATATTCCTTTCTCACACAGGGCTTCTGATTACTCAGAAACATGCCCCTCTTCCCT GAATAACCAAGAACATGTTCTATGAACCCAATCTCTGCCACATGTCAATACCTGCTCTTCAAAGCCCCTTTTGAAACTCAGTTTTGTGCCAAGTCCTCTG GATCTAATTACCTTAAACAAGCAGATTTAGCCATTTTTAAACAGACATTCCCAGTCATCCTGGTGCTTGTACTTCTCCTACATGTCATGAAGGACCTTGG ATTTACTGAGAACTCAGCCGTGGCCTTGGCTTTGATACTTATAGGTGTCAGCCCTTGGGCCGATTGTTGATCATCCAGAGCCTCAGTTCTGTACTTGTAA AGTGGAGACAGCAGTTCTCATCCTCCATCCTTTTAGCCCATGGGGTGGTTGTAAGGCTGGATTGAAATATGCATGTGACTAAGCCATGTAGCTATAAAGT GAGGGATGACTTGTGTTTTGGATCACTTATTTTAATTCTACTTATAATCCACGGCTTAGAATATTTAAACATTGTTTCTATTAAACTAGAAAGGTTCAGC ATTTCTGTCATTTACTTCTGCTATGATACACAAGAACTTATGTTGGAATGAAGTGAAAAGTAAAATGGCCATTCTTATGAACCTACAAAA

refseq_TMEM10.F1 (forward primer)
refseq_TMEM10.R1 (reverse primer)
Single exon skipping

Frame 0

NVDSRQLGMEWPASASCNPLFPKGCRLQKPPSS QASCGFFAEMEV*PRKQPEK*GQKIKAKRVGEPG HTRRPCSSSPSFPRDGLRAWLLP*P*MAWPGFS WSHLSACLCSFVS*LFLQMKDTSQ*SQ*ERSLP KAVYEEGSWETVRNEFFTELHPAGEHNVLSCHRW ERNGLWALSWISGGHTIAGGHSPAGGFTIYFDS PKKKQH*GHGGK*QTM*NFRN**QSQDI*ES*E ITHT*EEYDGSTRGPHICEDCSRKRGTCA*PLPS YYRNGKKEGIVVACAQTEPGMMQLSQGAADLAL EQG*KPRVLYLERKDAKLLLNQSKFHLQLWNTL GLICLFRGHPQHG*FQLSDLVL*LVHVTHQMGSL DPIPAPSGNLLFFVILGKGLGF*VSCLLIFFFH ILFLKKAIRSDFHGSVAEVSLVQVGIQMKLMQD V*EEAVNCF*ISQGRNHVEPHIP*PQGSTWLNHV TQQWKEYGLLSHTYH*AAVRLWRSCLTFSSLSF CFFKGGEIFASCHN*KD*IRNKGKCLLLSCQSK C*FSLSTTFFLPLPILLA**NS*SPAFVPHSHRA TQGNI*DKLSPWPMIQIVI*R*F*VLLVVCESS NLGVIVSSYESGKGSFLQVPNSKYRDWWCYI*P *RC*C*WKFMFHIKTTLCLYNETFCLIFKVRHYD TSDGSSSNNFNFCALGIVVKVTTSFILFFKGFR LNKSP*AHA*HCRFSLLRTVSKEAKWKRRGYFK WCWPIEPIGQTITRLPYFGWITPGEATLQLSLIP VTPLPIFQSIPSLFFFSSVLFFCLQYEFHFLCV FGQTSF*HVSATLPHTWPRRHIIHCSYLCL*SE SI*GGQFCDGLCVC*K*RWGAAGKARVFPKDY*K *GLYLLCGVEPSLLGEKNQVLGYLGESCLAERK IKRTQGDGDRTTGMGQGATCLPFSQLGTGFHFH SHEEASRQPGSPMYSHCPLAGQASQWEGLGPGHL KFIQQLHEPHRYPRKYSFLTQGF*LLRNMPLFP E*PRTCSMNPISATCQYLLFKAPFETQFCAKSS GSNYLKQADLAIFKQTFPVILVLVLLLHVMKDLG FTENSAVALALILIGVSPWADC*SSRASVLYL* SGDSSSHPPSF*PMGWL*GWIEICM*LSHVAIK *GMTCVLDHLF*FYL*STA*NI*TLFLLN*KGSA FLSFTSAMIHKNLCWNEVKSKMAILMNLQ

Frame 1

MWTPVSWGWSGQPQPHVTHCFQRAAGCRSPQAL RPAVASLLRWRYSQESSLKSKDRKSRQRGWVNQ AIHVGHAAAAHLSRGMD*GLGYSPDHKWLGQGSL GATSQPASAALSVNCSYK*KTQANKASEKGAYQ RQCTKKVPGRLSEMSFSLNFTLPANTTSSPVTG GKETDCGPSLGLAAGIPLLVATALLVALLFTLIH RRRSSIEAMEESDRPCEISEIDDNPKISENPRR SPTHEKNTMGAQEAHIYVKTVAGSEEPVHDRYR PTIEMERRRGLWWLVPRLSLE*CSSVKEQQTWHW NRVENPGFCTWRGKMPSCFLINPNFIYSSGTLW G*FVSLGDIPNMVNSNSQILCFS*YM*LTRWGP *ILFLLPVGICFSLSFWERGLVSECLAFSSFFFI SFFSKKPSDLTFMEVLLRSAWCKLGYK*NLCRM CERKQLIVSEYLRVGTMWSHTFPDHREAPGSIM SHSSGKNTDS*VTPTTEQLYDFGEVV*HFQASVF AFLKEGKYLPHVIIEKIK*EIKGSVCYLVASQN VSSLSLPPSSYLFPYCLPDKTANHQHLFPIVTG PHKGTFRTNFLHGL*SKLLSKDDSRCCW*YVNLP I*V*SCPHMNQEKAVSYKFRIPNTETGGVTFNL KDVNVDGNSCFILKQHFVFTMKHFA*FLK*DIM IPLMAVPQITLTFVL*G*LLKLQLLLFYFLKASD *TRALKPTHSIAASAC*GLSPRRPNGKGEATSS GVGPLSLLGKL*PGCLILGGLLQERPPSSFLLS Q*LLFPFSNPSPAFFFFLLYSSFAFNMSFISSVS LGRLPSNMCQLPYHTPGLGDTSFIAPTCVCNQR VFKEGSSATDCVCVESKDGGPRGRQEFFQKIIR NEGCIYSVE*NQVYLEKRTKSLDI*GKAVWQKEK SRGPKGMETGPQEWAKEQRACHSASLGQAFTFT PMRRLPGSLVPPCIAIAL*QARPPSGKAWVQGI LSSSSSSMSHTDILENIPFSHRASDYSETCPSSL NNQEHVL*TQSLPHVNTCSSKPLLKLSFVPSPL DLITLNKQI*PFLNRHSQSSWCLYFSYMS*RTL DLLRTQPWPWL*YL*VSALGPIVDHPEPQFCTCK VETAVLILHPFSPWGGCKAGLKYACD*AM*L*S EG*LVFWITYFNSTYNPRLRIFKHCFY*TRKVQ HFCHLLLL*YTRTYVGMK*KVKWPFL*TYK

Frame 2

CGLPSAGDGVASLSLM*PIVSKGLQAAEAPKLS GQLWLLC*DGGIAKKAA*KVRTENQGKEGG*TR PYTSAMQQQPIFPEGWTEGLATPLTINGLARVL LEPPLSLPLQLCQLTVPTNERHKPIKPVRKELTK GSVRRRFLGDCQK*VFH*TSPCRRTQRPLLSQV GKKRTVGPLLD*RRAYHCWWPQPCWWLYYLL*F TEEEAALRPWRKVTDHVKFQKLMTIPRYLRILGD HPHMRRIRWEHKRPTYM*RL*QEARNLCMTVTV LL*KWKEGGDCGGLCPD*AWNDAAQSRSSRPGT GTGLKTQGFVLGEERCQAAS*SIQISFTALEHFG ADLSL*GTSPTWLIPTLRSCALVSTCDSPDGVL RSYSCSQWEFAFLCHFGKGAWFLSVLPSHLFFS YPFSQKSHQI*LSWKCC*GQPGASWDTNETYAGC VRGSS*LFLNISG*EPCGATHSLTTGKHLAQSC HTAVERIRTLKSHLPLSSCTTLEKLFNIFKPQF LLF*RRGNICLMS*LKRLNKK*REVSAT*LPVKM LVLSLYHLLPTSSHIACLIKQLITSICSP*SQG HTREHLGQTFSMAYDPNCYLKMILGVAGSM*IF QSRCDRVLI*IRKRQFLTSSEFQIQRLVVLHLTL KMLMLMEIHVSY*NNTLSLQ*NILLNF*SKTL* YL*WQFLK*L*LLCFRDSC*SYNFFYFIF*RLQ IKQEPLSPRIALPLQLAEDCLQGGQMEKERLLQV VLAH*AYWANYNQVALFWVDYSRRGHPPAFSYP SNSSSHFPIHPQPFFFFFCTLLLPSI*VSFPLC LWADFLLTCVSYPTTHLA*ETHHSLLLLVSVIRE YLRRAVLRRTVCVLKVKMGGRGEGKSFSKRLLE MRAVSTLWSRTKSTWRKEPSPWISRGKLFGRKK NQEDPRGWRQDHRNGPRSNVPAIQPAWDRLSLSL P*GGFQAAWFPHV*PLPSSRPGLPVGRPGSRAS *VHPAAP*ATQIS*KIFLSHTGLLITQKHAPLP *ITKNMFYEPNLCHMSIPALQSPF*NSVLCQVLW I*LP*TSRFSHF*TDIPSHPGACTSPTCHEGPW IY*ELSRGLGFDTYRCQPLGRLLIIQSLSSVLV KWRQQFSSSILLAHGVVVRLD*NMHVTKPCSYKV RDDLCFGSLILILLIIHGLEYLNIVSIKLERFS ISVIYFCYDTQELMLE*SEK*NGHSYEPTK

Sequence NM_001040103

AATGTGGACTCCCGTCAGCTGGGGATGGAGTGGCCAGCCTCAGCCTCATGTAACCCATTGTTTCCAAAGGGCTGCAGGCTGCAGAAGCCCCCAAGCTCTC AGGCCAGCTGTGGCTTCTTTGCTGAGATGGAGGTATAGCCAAGAAAGCAGCCTGAAAAGTAAGGACAGAAAATCAAGGCAAAGAGGGTGGGTGAACCAGG CCATACACGTCGGCCATGCAGCAGCAGCCCATCTTTCCCGAGGGATGGACTGAGGGCTTGGCTACTCCCCTGACCATAAATGGCTTGGCCAGGGTTCTCT TGGAGCCACCTCTCAGCCTGCCTCTGCAGCTTTGTCAGTTAACTGTTCCTACAAATGAAAGACACAAGCCAATAAAGCCAGTGAGAAAGGAGCTTACCAA AGGCAGTGTACGAAGAAGGTTCCTGGGAGACTGTCAGAAATGAGTTTTTCACTGAACTTCACCCTGCCGGCGAACACACACTGAAAGTCCTGGGCAGCTC TCTGGACAATGCGGATGACGTCCTCTCCTGTCACAGGTGGGAAAGAAACGGACTGTGGGCCCTCTCTTGGATTAGCGGCGGGCATACCATTGCTGGTGGC CACAGCCCTGCTGGTGGCTTTACTATTTACTTTGATTCACCGAAGAAGAAGCAGCATTGAGGCCATGGAGGAAAGTGACAGACCATGTGAAATTTCAGAA ATTGATGACAATCCCAAGATATCTGAGAATCCTAGGAGATCACCCACACATGAGAAGAATACGATGGGAGCACAAGAGGCCCACATATATGTGAAGACTG TAGCAGGAAGCGAGGAACCTGTGCATGACCGTTACCGTCCTACTATAGAAATGGAAAGAAGGAGGGGATTGTGGTGGCTTGTGCCCAGACTGAGCCTGGA ATGATGCAGCTCAGTCAAGGAGCAGCAGACCTGGCACTGGAACAGGGTTGAAAACCCAGGGTTTTGTACTTGGAGAGGAAAGATGCCAAGCTGCTTCTTA ATCAATCCAAATTTCATTTACAGCTCTGGAACACTTTGGGGCTGATTTGTCTCTTTAGGGGACATCCCCAACATGGTTAATTCCAACTCTCAGATCTTGT GCTTTAGTTAGTACATGTGACTCACCAGATGGGGTCCTTAGATCCTATTCCTGCTCCCAGTGGGAATTTGCTTTTCTTTGTCATTTTGGGAAAGGGGCTT GGTTTCTGAGTGTCTTGCCTTCTCATCTTTTTTTTTCATATCCTTTTTCTCAAAAAAGCCATCAGATCTGACTTTCATGGAAGTGTTGCTGAGGTCAGCC TGGTGCAAGTTGGGATACAAATGAAACTTATGCAGGATGTGTGAGAGGAAGCAGTTAATTGTTTCTGAATATCTCAGGGTAGGAACCATGTGGAGCCACA CATTCCCTGACCACAGGGAAGCACCTGGCTCAATCATGTCACACAGCAGTGGAAAGAATACGGACTCTTAAGTCACACCTACCACTGAGCAGCTGTACGA CTTTGGAGAAGTTGTTTAACATTTTCAAGCCTCAGTTTTTGCTTTTTTAAAGGAGGGGAAATATTTGCCTCATGTCATAATTGAAAAGATTAAATAAGAA ATAAAGGGAAGTGTCTGCTACTTAGTTGCCAGTCAAAATGTTAGTTCTCTCTCTCTACCACCTTCTTCCTACCTCTTCCCATATTGCTTGCCTGATAAAA CAGCTAATCACCAGCATTTGTTCCCCATAGTCACAGGGCCACACAAGGGAACATTTAGGACAAACTTTCTCCATGGCCTATGATCCAAATTGTTATCTAA AGATGATTCTAGGTGTTGCTGGTAGTATGTGAATCTTCCAATCTAGGTGTGATCGTGTCCTCATATGAATCAGGAAAAGGCAGTTTCTTACAAGTTCCGA ATTCCAAATACAGAGACTGGTGGTGTTACATTTAACCTTAAAGATGTTAATGTTGATGGAAATTCATGTTTCATATTAAAACAACACTTTGTCTTTACAA TGAAACATTTTGCTTAATTTTTAAAGTAAGACATTATGATACCTCTGATGGCAGTTCCTCAAATAACTTTAACTTTTGTGCTTTAGGGATAGTTGTTAAA GTTACAACTTCTTTTATTTTATTTTTTAAAGGCTTCAGATTAAACAAGAGCCCTTAAGCCCACGCATAGCATTGCCGCTTCAGCTTGCTGAGGACTGTCT CCAAGGAGGCCAAATGGAAAAGGAGAGGCTACTTCAAGTGGTGTTGGCCCATTGAGCCTATTGGGCAAACTATAACCAGGTTGCCTTATTTTGGGTGGAT TACTCCAGGAGAGGCCACCCTCCAGCTTTCTCTTATCCCAGTAACTCCTCTTCCCATTTTCCAATCCATCCCCAGCCTTTTTTTTTTTTCTTCTGTACTC TTCTTTTGCCTTCAATATGAGTTTCATTTCCTCTGTGTCTTTGGGCAGACTTCCTTCTAACATGTGTCAGCTACCCTACCACACACCTGGCCTAGGAGAC ACATCATTCATTGCTCCTACTTGTGTCTGTAATCAGAGAGTATTTAAGGAGGGCAGTTCTGCGACGGACTGTGTGTGTGTTGAAAGTAAAGATGGGGGGC CGCGGGGAAGGCAAGAGTTTTTCCAAAAGATTATTAGAAATGAGGGCTGTATCTACTCTGTGGAGTAGAACCAAGTCTACTTGGAGAAAAGAACCAAGTC CTTGGATATCTAGGGGAAAGCTGTTTGGCAGAAAGAAAAATCAAGAGGACCCAAGGGGATGGAGACAGGACCACAGGAATGGGCCAAGGAGCAACGTGCC TGCCATTCAGCCAGCTTGGGACAGGCTTTCACTTTCACTCCCATGAGGAGGCTTCCAGGCAGCCTGGTTCCCCCATGTATAGCCATTGCCCTCTAGCAGG CCAGGCCTCCCAGTGGGAAGGCCTGGGTCCAGGGCATCTTAAGTTCATCCAGCAGCTCCATGAGCCACACAGATATCCTAGAAAATATTCCTTTCTCACA CAGGGCTTCTGATTACTCAGAAACATGCCCCTCTTCCCTGAATAACCAAGAACATGTTCTATGAACCCAATCTCTGCCACATGTCAATACCTGCTCTTCA AAGCCCCTTTTGAAACTCAGTTTTGTGCCAAGTCCTCTGGATCTAATTACCTTAAACAAGCAGATTTAGCCATTTTTAAACAGACATTCCCAGTCATCCT GGTGCTTGTACTTCTCCTACATGTCATGAAGGACCTTGGATTTACTGAGAACTCAGCCGTGGCCTTGGCTTTGATACTTATAGGTGTCAGCCCTTGGGCC GATTGTTGATCATCCAGAGCCTCAGTTCTGTACTTGTAAAGTGGAGACAGCAGTTCTCATCCTCCATCCTTTTAGCCCATGGGGTGGTTGTAAGGCTGGA TTGAAATATGCATGTGACTAAGCCATGTAGCTATAAAGTGAGGGATGACTTGTGTTTTGGATCACTTATTTTAATTCTACTTATAATCCACGGCTTAGAA TATTTAAACATTGTTTCTATTAAACTAGAAAGGTTCAGCATTTCTGTCATTTACTTCTGCTATGATACACAAGAACTTATGTTGGAATGAAGTGAAAAGT AAAATGGCCATTCTTATGAACCTACAAAA

refseq_TMEM10.F1 (forward primer)
refseq_TMEM10.R1 (reverse primer)
Single exon skipping

Frame 0

NVDSRQLGMEWPASASCNPLFPKGCRLQKPPSS QASCGFFAEMEV*PRKQPEK*GQKIKAKRVGEPG HTRRPCSSSPSFPRDGLRAWLLP*P*MAWPGFS WSHLSACLCSFVS*LFLQMKDTSQ*SQ*ERSLP KAVYEEGSWETVRNEFFTELHPAGEHTLKVLGSS LDNADDVLSCHRWERNGLWALSWISGGHTIAGG HSPAGGFTIYFDSPKKKQH*GHGGK*QTM*NFR N**QSQDI*ES*EITHT*EEYDGSTRGPHICEDC SRKRGTCA*PLPSYYRNGKKEGIVVACAQTEPG MMQLSQGAADLALEQG*KPRVLYLERKDAKLLL NQSKFHLQLWNTLGLICLFRGHPQHG*FQLSDLV L*LVHVTHQMGSLDPIPAPSGNLLFFVILGKGL GF*VSCLLIFFFHILFLKKAIRSDFHGSVAEVS LVQVGIQMKLMQDV*EEAVNCF*ISQGRNHVEPH IP*PQGSTWLNHVTQQWKEYGLLSHTYH*AAVR LWRSCLTFSSLSFCFFKGGEIFASCHN*KD*IR NKGKCLLLSCQSKC*FSLSTTFFLPLPILLA**N S*SPAFVPHSHRATQGNI*DKLSPWPMIQIVI* R*F*VLLVVCESSNLGVIVSSYESGKGSFLQVP NSKYRDWWCYI*P*RC*C*WKFMFHIKTTLCLYN ETFCLIFKVRHYDTSDGSSSNNFNFCALGIVVK VTTSFILFFKGFRLNKSP*AHA*HCRFSLLRTV SKEAKWKRRGYFKWCWPIEPIGQTITRLPYFGWI TPGEATLQLSLIPVTPLPIFQSIPSLFFFSSVL FFCLQYEFHFLCVFGQTSF*HVSATLPHTWPRR HIIHCSYLCL*SESI*GGQFCDGLCVC*K*RWGA AGKARVFPKDY*K*GLYLLCGVEPSLLGEKNQV LGYLGESCLAERKIKRTQGDGDRTTGMGQGATC LPFSQLGTGFHFHSHEEASRQPGSPMYSHCPLAG QASQWEGLGPGHLKFIQQLHEPHRYPRKYSFLT QGF*LLRNMPLFPE*PRTCSMNPISATCQYLLF KAPFETQFCAKSSGSNYLKQADLAIFKQTFPVIL VLVLLLHVMKDLGFTENSAVALALILIGVSPWA DC*SSRASVLYL*SGDSSSHPPSF*PMGWL*GW IEICM*LSHVAIK*GMTCVLDHLF*FYL*STA*N I*TLFLLN*KGSAFLSFTSAMIHKNLCWNEVKS KMAILMNLQ

Frame 1

MWTPVSWGWSGQPQPHVTHCFQRAAGCRSPQAL RPAVASLLRWRYSQESSLKSKDRKSRQRGWVNQ AIHVGHAAAAHLSRGMD*GLGYSPDHKWLGQGSL GATSQPASAALSVNCSYK*KTQANKASEKGAYQ RQCTKKVPGRLSEMSFSLNFTLPANTH*KSWAA LWTMRMTSSPVTGGKETDCGPSLGLAAGIPLLVA TALLVALLFTLIHRRRSSIEAMEESDRPCEISE IDDNPKISENPRRSPTHEKNTMGAQEAHIYVKT VAGSEEPVHDRYRPTIEMERRRGLWWLVPRLSLE *CSSVKEQQTWHWNRVENPGFCTWRGKMPSCFL INPNFIYSSGTLWG*FVSLGDIPNMVNSNSQIL CFS*YM*LTRWGP*ILFLLPVGICFSLSFWERGL VSECLAFSSFFFISFFSKKPSDLTFMEVLLRSA WCKLGYK*NLCRMCERKQLIVSEYLRVGTMWSH TFPDHREAPGSIMSHSSGKNTDS*VTPTTEQLYD FGEVV*HFQASVFAFLKEGKYLPHVIIEKIK*E IKGSVCYLVASQNVSSLSLPPSSYLFPYCLPDK TANHQHLFPIVTGPHKGTFRTNFLHGL*SKLLSK DDSRCCW*YVNLPI*V*SCPHMNQEKAVSYKFR IPNTETGGVTFNLKDVNVDGNSCFILKQHFVFT MKHFA*FLK*DIMIPLMAVPQITLTFVL*G*LLK LQLLLFYFLKASD*TRALKPTHSIAASAC*GLS PRRPNGKGEATSSGVGPLSLLGKL*PGCLILGG LLQERPPSSFLLSQ*LLFPFSNPSPAFFFFLLYS SFAFNMSFISSVSLGRLPSNMCQLPYHTPGLGD TSFIAPTCVCNQRVFKEGSSATDCVCVESKDGG PRGRQEFFQKIIRNEGCIYSVE*NQVYLEKRTKS LDI*GKAVWQKEKSRGPKGMETGPQEWAKEQRA CHSASLGQAFTFTPMRRLPGSLVPPCIAIAL*Q ARPPSGKAWVQGILSSSSSSMSHTDILENIPFSH RASDYSETCPSSLNNQEHVL*TQSLPHVNTCSS KPLLKLSFVPSPLDLITLNKQI*PFLNRHSQSS WCLYFSYMS*RTLDLLRTQPWPWL*YL*VSALGP IVDHPEPQFCTCKVETAVLILHPFSPWGGCKAG LKYACD*AM*L*SEG*LVFWITYFNSTYNPRLR IFKHCFY*TRKVQHFCHLLLL*YTRTYVGMK*KV KWPFL*TYK

Frame 2

CGLPSAGDGVASLSLM*PIVSKGLQAAEAPKLS GQLWLLC*DGGIAKKAA*KVRTENQGKEGG*TR PYTSAMQQQPIFPEGWTEGLATPLTINGLARVL LEPPLSLPLQLCQLTVPTNERHKPIKPVRKELTK GSVRRRFLGDCQK*VFH*TSPCRRTHTESPGQL SGQCG*RPLLSQVGKKRTVGPLLD*RRAYHCWW PQPCWWLYYLL*FTEEEAALRPWRKVTDHVKFQK LMTIPRYLRILGDHPHMRRIRWEHKRPTYM*RL *QEARNLCMTVTVLL*KWKEGGDCGGLCPD*AW NDAAQSRSSRPGTGTGLKTQGFVLGEERCQAAS* SIQISFTALEHFGADLSL*GTSPTWLIPTLRSC ALVSTCDSPDGVLRSYSCSQWEFAFLCHFGKGA WFLSVLPSHLFFSYPFSQKSHQI*LSWKCC*GQP GASWDTNETYAGCVRGSS*LFLNISG*EPCGAT HSLTTGKHLAQSCHTAVERIRTLKSHLPLSSCT TLEKLFNIFKPQFLLF*RRGNICLMS*LKRLNKK *REVSAT*LPVKMLVLSLYHLLPTSSHIACLIK QLITSICSP*SQGHTREHLGQTFSMAYDPNCYL KMILGVAGSM*IFQSRCDRVLI*IRKRQFLTSSE FQIQRLVVLHLTLKMLMLMEIHVSY*NNTLSLQ *NILLNF*SKTL*YL*WQFLK*L*LLCFRDSC* SYNFFYFIF*RLQIKQEPLSPRIALPLQLAEDCL QGGQMEKERLLQVVLAH*AYWANYNQVALFWVD YSRRGHPPAFSYPSNSSSHFPIHPQPFFFFFCT LLLPSI*VSFPLCLWADFLLTCVSYPTTHLA*ET HHSLLLLVSVIREYLRRAVLRRTVCVLKVKMGG RGEGKSFSKRLLEMRAVSTLWSRTKSTWRKEPS PWISRGKLFGRKKNQEDPRGWRQDHRNGPRSNVP AIQPAWDRLSLSLP*GGFQAAWFPHV*PLPSSR PGLPVGRPGSRAS*VHPAAP*ATQIS*KIFLSH TGLLITQKHAPLP*ITKNMFYEPNLCHMSIPALQ SPF*NSVLCQVLWI*LP*TSRFSHF*TDIPSHP GACTSPTCHEGPWIY*ELSRGLGFDTYRCQPLG RLLIIQSLSSVLVKWRQQFSSSILLAHGVVVRLD *NMHVTKPCSYKVRDDLCFGSLILILLIIHGLE YLNIVSIKLERFSISVIYFCYDTQELMLE*SEK *NGHSYEPTK