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Sequences

Sequence NM_138636

CTCCTGCATAGAGGGTACCATTCTGCGCTGCTGCAAGTTACGGAATGAAAAATTAGAACAACAGAAACATGGAAAACATGTTCCTTCAGTCGTCAATGCT
GACCTGCATTTTCCTGCTAATATCTGGTTCCTGTGAGTTATGCGCCGAAGAAAATTTTTCTAGAAGCTATCCTTGTGATGAGAAAAAGCAAAATGACTCA
GTTATTGCAGAGTGCAGCAATCGTCGACTACAGGAAGTTCCCCAAACGGTGGGCAAATATGTGACAGAACTAGACCTGTCTGATAATTTCATCACACACA
TAACGAATGAATCATTTCAAGGGCTGCAAAATCTCACTAAAATAAATCTAAACCACAACCCCAATGTACAGCACCAGAACGGAAATCCCGGTATACAATC
AAATGGCTTGAATATCACAGACGGGGCATTCCTCAACCTAAAAAACCTAAGGGAGTTACTGCTTGAAGACAACCAGTTACCCCAAATACCCTCTGGTTTG
CCAGAGTCTTTGACAGAACTTAGTCTAATTCAAAACAATATATACAACATAACTAAAGAGGGCATTTCAAGACTTATAAACTTGAAAAATCTCTATTTGG
CCTGGAACTGCTATTTTAACAAAGTTTGCGAGAAAACTAACATAGAAGATGGAGTATTTGAAACGCTGACAAATTTGGAGTTGCTATCACTATCTTTCAA
TTCTCTTTCACACGTGCCACCCAAACTGCCAAGCTCCCTACGCAAACTTTTTCTGAGCAACACCCAGATCAAATACATTAGTGAAGAAGATTTCAAGGGA
TTGATAAATTTAACATTACTAGATTTAAGCGGGAACTGTCCGAGGTGCTTCAATGCCCCATTTCCATGCGTGCCTTGTGATGGTGGTGCTTCAATTAATA
TAGATCGTTTTGCTTTTCAAAACTTGACCCAACTTCGATACCTAAACCTCTCTAGCACTTCCCTCAGGAAGATTAATGCTGCCTGGTTTAAAAATATGCC
TCATCTGAAGGTGCTGGATCTTGAATTCAACTATTTAGTGGGAGAAATAGCCTCTGGGGCATTTTTAACGATGCTGCCCCGCTTAGAAATACTTGACTTG
TCTTTTAACTATATAAAGGGGAGTTATCCACAGCATATTAATATTTCCAGAAACTTCTCTAAACTTTTGTCTCTACGGGCATTGCATTTAAGAGGTTATG
TGTTCCAGGAACTCAGAGAAGATGATTTCCAGCCCCTGATGCAGCTTCCAAACTTATCGACTATCAACTTGGGTATTAATTTTATTAAGCAAATCGATTT
CAAACTTTTCCAAAATTTCTCCAATCTGGAAATTATTTACTTGTCAGAAAACAGAATATCACCGTTGGTAAAAGATACCCGGCAGAGTTATGCAAATAGT
TCCTCTTTTCAACGTCATATCCGGAAACGACGCTCAACAGATTTTGAGTTTGACCCACATTCGAACTTTTATCATTTCACCCGTCCTTTAATAAAGCCAC
AATGTGCTGCTTATGGAAAAGCCTTAGATTTAAGCCTCAACAGTATTTTCTTCATTGGGCCAAACCAATTTGAAAATCTTCCTGACATTGCCTGTTTAAA
TCTGTCTGCAAATAGCAATGCTCAAGTGTTAAGTGGAACTGAATTTTCAGCCATTCCTCATGTCAAATATTTGGATTTGACAAACAATAGACTAGACTTT
GATAATGCTAGTGCTCTTACTGAATTGTCCGACTTGGAAGTTCTAGATCTCAGCTATAATTCACACTATTTCAGAATAGCAGGCGTAACACATCATCTAG
AATTTATTCAAAATTTCACAAATCTAAAAGTTTTAAACTTGAGCCACAACAACATTTATACTTTAACAGATAAGTATAACCTGGAAAGCAAGTCCCTGGT
AGAATTAGTTTTCAGTGGCAATCGCCTTGACATTTTGTGGAATGATGATGACAACAGGTATATCTCCATTTTCAAAGGTCTCAAGAATCTGACACGTCTG
GATTTATCCCTTAATAGGCTGAAGCACATCCCAAATGAAGCATTCCTTAATTTGCCAGCGAGTCTCACTGAACTACATATAAATGATAATATGTTAAAGT
TTTTTAACTGGACATTACTCCAGCAGTTTCCTCGTCTCGAGTTGCTTGACTTACGTGGAAACAAACTACTCTTTTTAACTGATAGCCTATCTGACTTTAC
ATCTTCCCTTCGGACACTGCTGCTGAGTCATAACAGGATTTCCCACCTACCCTCTGGCTTTCTTTCTGAAGTCAGTAGTCTGAAGCACCTCGATTTAAGT
TCCAATCTGCTAAAAACAATCAACAAATCCGCACTTGAAACTAAGACCACCACCAAATTATCTATGTTGGAACTACACGGAAACCCCTTTGAATGCACCT
GTGACATTGGAGATTTCCGAAGATGGATGGATGAACATCTGAATGTCAAAATTCCCAGACTGGTAGATGTCATTTGTGCCAGTCCTGGGGATCAAAGAGG
GAAGAGTATTGTGAGTCTGGAGCTAACAACTTGTGTTTCAGATGTCACTGCAGTGATATTATTTTTCTTCACGTTCTTTATCACCACCATGGTTATGTTG
GCTGCCCTGGCTCACCATTTGTTTTACTGGGATGTTTGGTTTATATATAATGTGTGTTTAGCTAAGGTAAAAGGCTACAGGTCTCTTTCCACATCCCAAA
CTTTCTATGATGCTTACATTTCTTATGACACCAAAGATGCCTCTGTTACTGACTGGGTGATAAATGAGCTGCGCTACCACCTTGAAGAGAGCCGAGACAA
AAACGTTCTCCTTTGTCTAGAGGAGAGGGATTGGGATCCGGGATTGGCCATCATCGACAACCTCATGCAGAGCATCAACCAAAGCAAGAAAACAGTATTT
GTTTTAACCAAAAAATATGCAAAAAGCTGGAACTTTAAAACAGCTTTTTACTTGGCTTTGCAGAGGCTAATGGATGAGAACATGGATGTGATTATATTTA
TCCTGCTGGAGCCAGTGTTACAGCATTCTCAGTATTTGAGGCTACGGCAGCGGATCTGTAAGAGCTCCATCCTCCAGTGGCCTGACAACCCGAAGGCAGA
AGGCTTGTTTTGGCAAACTCTGAGAAATGTGGTCTTGACTGAAAATGATTCACGGTATAACAATATGTATGTCGATTCCATTAAGCAATACTAACTGACG
TTAAGTCATGATTTCGCGCCATAATAAAGATGCAAAGGAATGACATTTCTGTATTAGTTATCTATTGCTATGTAACAAATTATCCCAAAACTTAGTGGTT
TAAAACAACACATTTGCTGGCCCACAGTTTTTGAGGGTCAGGAGTCCAGGCCCAGCATAACTGGGTCCTCTGCTCAGGGTGTCTCAGAGGCTGCAATGTA
GGTGTTCACCAGAGACATAGGCATCACTGGGGTCACACTCATGTGGTTGTTTTCTGGATTCAATTCCTCCTGGGCTATTGGCCAAAGGCTATACTCATGT
AAGCCATGCGAGCCTCTCCCACAAGGCAGCTTGCTTCATCAGAGCTAGCAAAAAAGAGAGGTTGCTAGCAAGATGAAGTCACAATCTTTTGTAATCGAAT
CAAAAAAGTGATATCTCATCACTTTGGCCATATTCTATTTGTTAGAAGTAAACCACAGGTCCCACCAGCTCCATGGGAGTGACCACCTCAGTCCAGGGAA
AACAGCTGAAGACCAAGATGGTGAGCTCTGATTGCTTCAGTTGGTCATCAACTATTTTCCCTTGACTGCTGTCCTGGGATGGCCTGCTATCTTGATGATA
GATTGTGAATATCAGGAGGCAGGGATCACTGTGGACCATCTTAGCAGTTGACCTAACACATCTTCTTTTCAATATCTAAGAACTTTTGCCACTGTGACTA
ATGGTCCTAATATTAAGCTGTTGTTTATATTTATCATATATCTATGGCTACATGGTTATATTATGCTGTGGTTGCGTTCGGTTTTATTTACAGTTGCTTT
TACAAATATTTGCTGTAACATTTGACTTCTAAGGTTTAGATGCCATTTAAGAACTGAGATGGATAGCTTTTAAAGCATCTTTTACTTCTTACCATTTTTT
AAAAGTATGCAGCTAAATTCGAAGCTTTTGGTCTATATTGTTAATTGCCATTGCTGTAAATCTTAAAATGAATGAATAAAAATGTTTCATTTTACAA
  • refseq_TLR8.F1 (forward primer)
  • refseq_TLR8.R1 (reverse primer)
  • Single exon skipping

Frame 0

LLHRGYHSALLQVTE*KIRTTETWKTCSFSRQC
*PAFSC*YLVPVSYAPKKIFLEAILVMRKSKMTQ
LLQSAAIVDYRKFPKRWANM*QN*TCLIISSHT
*RMNHFKGCKISLK*I*TTTPMYSTRTEIPVYN
QMA*ISQTGHSST*KT*GSYCLKTTSYPKYPLVC
QSL*QNLV*FKTIYTT*LKRAFQDL*T*KISIW
PGTAILTKFARKLT*KMEYLKR*QIWSCYHYLS
ILFHTCHPNCQAPYANFF*ATPRSNTLVKKISRD
**I*HY*I*AGTVRGASMPHFHACLVMVVLQLI
*IVLLFKT*PNFDT*TSLALPSGRLMLPGLKIC
LI*RCWILNSTI*WEK*PLGHF*RCCPA*KYLTC
LLTI*RGVIHSILIFPETSLNFCLYGHCI*EVM
CSRNSEKMISSP*CSFQTYRLSTWVLILLSKSI
SNFSKISPIWKLFTCQKTEYHRW*KIPGRVMQIV
PLFNVISGNDAQQILSLTHIRTFIISPVL**SH
NVLLMEKP*I*ASTVFSSLGQTNLKIFLTLPV*
ICLQIAMLKC*VELNFQPFLMSNIWI*QTID*TL
IMLVLLLNCPTWKF*ISAIIHTISE*QA*HII*
NLFKISQI*KF*T*ATTTFIL*QISITWKASPW
*N*FSVAIALTFCGMMMTTGISPFSKVSRI*HVW
IYPLIG*STSQMKHSLICQRVSLNYI*MIIC*S
FLTGHYSSSFLVSSCLTYVETNYSF*LIAYLTL
HLPFGHCC*VITGFPTYPLAFFLKSVV*STSI*V
PIC*KQSTNPHLKLRPPPNYLCWNYTETPLNAP
VTLEISEDGWMNI*MSKFPDW*MSFVPVLGIKE
GRVL*VWS*QLVFQMSLQ*YYFSSRSLSPPWLCW
LPWLTICFTGMFGLYIMCV*LR*KATGLFPHPK
LSMMLTFLMTPKMPLLLTG**MSCATTLKRAET
KTFSFV*RRGIGIRDWPSSTTSCRASTKARKQYL
F*PKNMQKAGTLKQLFTWLCRG*WMRTWM*LYL
SCWSQCYSILSI*GYGSGSVRAPSSSGLTTRRQ
KACFGKL*EMWS*LKMIHGITICMSIPLSNTN*R
*VMISRHNKDAKE*HFCISYLLLCNKLSQNLVV
*NNTFAGPQFLRVRSPGPA*LGPLLRVSQRLQC
RCSPET*ASLGSHSCGCFLDSIPPGLLAKGYTHV
SHASLSHKAACFIRASKKERLLAR*SHNLL*SN
QKSDISSLWPYSIC*K*TTGPTSSMGVTTSVQG
KQLKTKMVSSDCFSWSSTIFP*LLSWDGLLS***
IVNIRRQGSLWTILAVDLTHLLFNI*ELLPL*L
MVLILSCCLYLSYIYGYMVILCCGCVRFYLQLL
LQIFAVTFDF*GLDAI*ELRWIAFKASFTSYHFL
KVCS*IRSFWSILLIAIAVNLKMNE*KCFILQ

Frame 1

SCIEGTILRCCKLRNEKLEQQKHGKHVPSVVNA
DLHFPANIWFL*VMRRRKFF*KLSL**EKAK*L
SYCRVQQSSTTGSSPNGGQICDRTRPV**FHHTH
NE*IISRAAKSH*NKSKPQPQCTAPERKSRYTI
KWLEYHRRGIPQPKKPKGVTA*RQPVTPNTLWF
ARVFDRT*SNSKQYIQHN*RGHFKTYKLEKSLFG
LELLF*QSLREN*HRRWSI*NADKFGVAITIFQ
FSFTRATQTAKLPTQTFSEQHPDQIH**RRFQG
IDKFNITRFKRELSEVLQCPISMRAL*WWCFN*Y
RSFCFSKLDPTSIPKPL*HFPQED*CCLV*KYA
SSEGAGS*IQLFSGRNSLWGIFNDAAPLRNT*L
VF*LYKGELSTAY*YFQKLL*TFVSTGIAFKRLC
VPGTQRR*FPAPDAASKLIDYQLGY*FY*ANRF
QTFPKFLQSGNYLLVRKQNITVGKRYPAELCK*
FLFSTSYPETTLNRF*V*PTFELLSFHPSFNKAT
MCCLWKSLRFKPQQYFLHWAKPI*KSS*HCLFK
SVCK*QCSSVKWN*IFSHSSCQIFGFDKQ*TRL
**C*CSY*IVRLGSSRSQL*FTLFQNSRRNTSSR
IYSKFHKSKSFKLEPQQHLYFNR*V*PGKQVPG
RISFQWQSP*HFVE***QQVYLHFQRSQESDTS
GFIP**AEAHPK*SIP*FASESH*TTYK**YVKV
F*LDITPAVSSSRVA*LTWKQTTLFN**PI*LY
IFPSDTAAES*QDFPPTLWLSF*SQ*SEAPRFK
FQSAKNNQQIRT*N*DHHQIIYVGTTRKPL*MHL
*HWRFPKMDG*TSECQNSQTGRCHLCQSWGSKR
EEYCESGANNLCFRCHCSDIIFLHVLYHHHGYV
GCPGSPFVLLGCLVYI*CVFS*GKRLQVSFHIPN
FL*CLHFL*HQRCLCY*LGDK*AALPP*REPRQ
KRSPLSRGEGLGSGIGHHRQPHAEHQPKQENSI
CFNQKICKKLEL*NSFLLGFAEANG*EHGCDYIY
PAGASVTAFSVFEATAADL*ELHPPVA*QPEGR
RLVLANSEKCGLD*K*FTV*QYVCRFH*AILTD
VKS*FRAIIKMQRNDISVLVIYCYVTNYPKT*WF
KTTHLLAHSF*GSGVQAQHNWVLCSGCLRGCNV
GVHQRHRHHWGHTHVVVFWIQFLLGYWPKAILM
*AMRASPTRQLASSELAKKRGC*QDEVTIFCNRI
KKVISHHFGHILFVRSKPQVPPAPWE*PPQSRE
NS*RPRW*ALIASVGHQLFSLDCCPGMACYLDD
RL*ISGGRDHCGPS*QLT*HIFFSISKNFCHCD*
WS*Y*AVVYIYHISMATWLYYAVVAFGFIYSCF
YKYLL*HLTSKV*MPFKN*DG*LLKHLLLLTIF
*KYAAKFEAFGLYC*LPLL*ILK*MNKNVSFY

Frame 2

PA*RVPFCAAASYGMKN*NNRNMENMFLQSSML
TCIFLLISGSCELCAEENFSRSYPCDEKKQNDS
VIAECSNRRLQEVPQTVGKYVTELDLSDNFITH
ITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQS
NGLNITDGAFLNLKNLRELLLEDNQLPQIPSGL
PESLTELSLIQNNIYNITKEGISRLINLKNLYL
AWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFN
SLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKG
LINLTLLDLSGNCPRCFNAPFPCVPCDGGASIN
IDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP
HLKVLDLEFNYLVGEIASGAFLTMLPRLEILDL
SFNYIKGSYPQHINISRNFSKLLSLRALHLRGY
VFQELREDDFQPLMQLPNLSTINLGINFIKQIDF
KLFQNFSNLEIIYLSENRISPLVKDTRQSYANS
SSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKP
QCAAYGKALDLSLNSIFFIGPNQFENLPDIACLN
LSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDF
DNASALTELSDLEVLDLSYNSHYFRIAGVTHHL
EFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLV
ELVFSGNRLDILWNDDDNRYISIFKGLKNLTRL
DLSLNRLKHIPNEAFLNLPASLTELHINDNMLK
FFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFT
SSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLS
SNLLKTINKSALETKTTTKLSMLELHGNPFECT
CDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRG
KSIVSLELTTCVSDVTAVILFFFTFFITTMVML
AALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQ
TFYDAYISYDTKDASVTDWVINELRYHLEESRDK
NVLLCLEERDWDPGLAIIDNLMQSINQSKKTVF
VLTKKYAKSWNFKTAFYLALQRLMDENMDVIIF
ILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAE
GLFWQTLRNVVLTENDSRYNNMYVDSIKQY*LT
LSHDFAP**RCKGMTFLY*LSIAM*QIIPKLSG
LKQHICWPTVFEGQESRPSITGSSAQGVSEAAM*
VFTRDIGITGVTLMWLFSGFNSSWAIGQRLYSC
KPCEPLPQGSLLHQS*QKREVASKMKSQSFVIE
SKK*YLITLAIFYLLEVNHRSHQLHGSDHLSPGK
TAEDQDGEL*LLQLVINYFPLTAVLGWPAILMI
DCEYQEAGITVDHLSS*PNTSSFQYLRTFATVT
NGPNIKLLFIFIIYLWLHGYIMLWLRSVLFTVAF
TNICCNI*LLRFRCHLRTEMDSF*SIFYFLPFF
KSMQLNSKLLVYIVNCHCCKS*NE*IKMFHFT

Sequence NM_016610

CTCCTGCATAGAGGGTACCATTCTGCGCTGCTGCAAGTTACGGAATGAAAAATTAGAACAACAGAAACATGGTTCTCTTGACACTTCAGTGTTAGGGAAC
ATCAGCAAGACCCATCCCAGGAGACCTTGAAGGAAGCCTTTGAAAGGGAGAATGAAGGAGTCATCTTTGCAAAATAGCTCCTGCAGCCTGGGAAAGGAGA
CTAAAAAGGAAAACATGTTCCTTCAGTCGTCAATGCTGACCTGCATTTTCCTGCTAATATCTGGTTCCTGTGAGTTATGCGCCGAAGAAAATTTTTCTAG
AAGCTATCCTTGTGATGAGAAAAAGCAAAATGACTCAGTTATTGCAGAGTGCAGCAATCGTCGACTACAGGAAGTTCCCCAAACGGTGGGCAAATATGTG
ACAGAACTAGACCTGTCTGATAATTTCATCACACACATAACGAATGAATCATTTCAAGGGCTGCAAAATCTCACTAAAATAAATCTAAACCACAACCCCA
ATGTACAGCACCAGAACGGAAATCCCGGTATACAATCAAATGGCTTGAATATCACAGACGGGGCATTCCTCAACCTAAAAAACCTAAGGGAGTTACTGCT
TGAAGACAACCAGTTACCCCAAATACCCTCTGGTTTGCCAGAGTCTTTGACAGAACTTAGTCTAATTCAAAACAATATATACAACATAACTAAAGAGGGC
ATTTCAAGACTTATAAACTTGAAAAATCTCTATTTGGCCTGGAACTGCTATTTTAACAAAGTTTGCGAGAAAACTAACATAGAAGATGGAGTATTTGAAA
CGCTGACAAATTTGGAGTTGCTATCACTATCTTTCAATTCTCTTTCACACGTGCCACCCAAACTGCCAAGCTCCCTACGCAAACTTTTTCTGAGCAACAC
CCAGATCAAATACATTAGTGAAGAAGATTTCAAGGGATTGATAAATTTAACATTACTAGATTTAAGCGGGAACTGTCCGAGGTGCTTCAATGCCCCATTT
CCATGCGTGCCTTGTGATGGTGGTGCTTCAATTAATATAGATCGTTTTGCTTTTCAAAACTTGACCCAACTTCGATACCTAAACCTCTCTAGCACTTCCC
TCAGGAAGATTAATGCTGCCTGGTTTAAAAATATGCCTCATCTGAAGGTGCTGGATCTTGAATTCAACTATTTAGTGGGAGAAATAGCCTCTGGGGCATT
TTTAACGATGCTGCCCCGCTTAGAAATACTTGACTTGTCTTTTAACTATATAAAGGGGAGTTATCCACAGCATATTAATATTTCCAGAAACTTCTCTAAA
CTTTTGTCTCTACGGGCATTGCATTTAAGAGGTTATGTGTTCCAGGAACTCAGAGAAGATGATTTCCAGCCCCTGATGCAGCTTCCAAACTTATCGACTA
TCAACTTGGGTATTAATTTTATTAAGCAAATCGATTTCAAACTTTTCCAAAATTTCTCCAATCTGGAAATTATTTACTTGTCAGAAAACAGAATATCACC
GTTGGTAAAAGATACCCGGCAGAGTTATGCAAATAGTTCCTCTTTTCAACGTCATATCCGGAAACGACGCTCAACAGATTTTGAGTTTGACCCACATTCG
AACTTTTATCATTTCACCCGTCCTTTAATAAAGCCACAATGTGCTGCTTATGGAAAAGCCTTAGATTTAAGCCTCAACAGTATTTTCTTCATTGGGCCAA
ACCAATTTGAAAATCTTCCTGACATTGCCTGTTTAAATCTGTCTGCAAATAGCAATGCTCAAGTGTTAAGTGGAACTGAATTTTCAGCCATTCCTCATGT
CAAATATTTGGATTTGACAAACAATAGACTAGACTTTGATAATGCTAGTGCTCTTACTGAATTGTCCGACTTGGAAGTTCTAGATCTCAGCTATAATTCA
CACTATTTCAGAATAGCAGGCGTAACACATCATCTAGAATTTATTCAAAATTTCACAAATCTAAAAGTTTTAAACTTGAGCCACAACAACATTTATACTT
TAACAGATAAGTATAACCTGGAAAGCAAGTCCCTGGTAGAATTAGTTTTCAGTGGCAATCGCCTTGACATTTTGTGGAATGATGATGACAACAGGTATAT
CTCCATTTTCAAAGGTCTCAAGAATCTGACACGTCTGGATTTATCCCTTAATAGGCTGAAGCACATCCCAAATGAAGCATTCCTTAATTTGCCAGCGAGT
CTCACTGAACTACATATAAATGATAATATGTTAAAGTTTTTTAACTGGACATTACTCCAGCAGTTTCCTCGTCTCGAGTTGCTTGACTTACGTGGAAACA
AACTACTCTTTTTAACTGATAGCCTATCTGACTTTACATCTTCCCTTCGGACACTGCTGCTGAGTCATAACAGGATTTCCCACCTACCCTCTGGCTTTCT
TTCTGAAGTCAGTAGTCTGAAGCACCTCGATTTAAGTTCCAATCTGCTAAAAACAATCAACAAATCCGCACTTGAAACTAAGACCACCACCAAATTATCT
ATGTTGGAACTACACGGAAACCCCTTTGAATGCACCTGTGACATTGGAGATTTCCGAAGATGGATGGATGAACATCTGAATGTCAAAATTCCCAGACTGG
TAGATGTCATTTGTGCCAGTCCTGGGGATCAAAGAGGGAAGAGTATTGTGAGTCTGGAGCTAACAACTTGTGTTTCAGATGTCACTGCAGTGATATTATT
TTTCTTCACGTTCTTTATCACCACCATGGTTATGTTGGCTGCCCTGGCTCACCATTTGTTTTACTGGGATGTTTGGTTTATATATAATGTGTGTTTAGCT
AAGGTAAAAGGCTACAGGTCTCTTTCCACATCCCAAACTTTCTATGATGCTTACATTTCTTATGACACCAAAGATGCCTCTGTTACTGACTGGGTGATAA
ATGAGCTGCGCTACCACCTTGAAGAGAGCCGAGACAAAAACGTTCTCCTTTGTCTAGAGGAGAGGGATTGGGATCCGGGATTGGCCATCATCGACAACCT
CATGCAGAGCATCAACCAAAGCAAGAAAACAGTATTTGTTTTAACCAAAAAATATGCAAAAAGCTGGAACTTTAAAACAGCTTTTTACTTGGCTTTGCAG
AGGCTAATGGATGAGAACATGGATGTGATTATATTTATCCTGCTGGAGCCAGTGTTACAGCATTCTCAGTATTTGAGGCTACGGCAGCGGATCTGTAAGA
GCTCCATCCTCCAGTGGCCTGACAACCCGAAGGCAGAAGGCTTGTTTTGGCAAACTCTGAGAAATGTGGTCTTGACTGAAAATGATTCACGGTATAACAA
TATGTATGTCGATTCCATTAAGCAATACTAACTGACGTTAAGTCATGATTTCGCGCCATAATAAAGATGCAAAGGAATGACATTTCTGTATTAGTTATCT
ATTGCTATGTAACAAATTATCCCAAAACTTAGTGGTTTAAAACAACACATTTGCTGGCCCACAGTTTTTGAGGGTCAGGAGTCCAGGCCCAGCATAACTG
GGTCCTCTGCTCAGGGTGTCTCAGAGGCTGCAATGTAGGTGTTCACCAGAGACATAGGCATCACTGGGGTCACACTCATGTGGTTGTTTTCTGGATTCAA
TTCCTCCTGGGCTATTGGCCAAAGGCTATACTCATGTAAGCCATGCGAGCCTCTCCCACAAGGCAGCTTGCTTCATCAGAGCTAGCAAAAAAGAGAGGTT
GCTAGCAAGATGAAGTCACAATCTTTTGTAATCGAATCAAAAAAGTGATATCTCATCACTTTGGCCATATTCTATTTGTTAGAAGTAAACCACAGGTCCC
ACCAGCTCCATGGGAGTGACCACCTCAGTCCAGGGAAAACAGCTGAAGACCAAGATGGTGAGCTCTGATTGCTTCAGTTGGTCATCAACTATTTTCCCTT
GACTGCTGTCCTGGGATGGCCTGCTATCTTGATGATAGATTGTGAATATCAGGAGGCAGGGATCACTGTGGACCATCTTAGCAGTTGACCTAACACATCT
TCTTTTCAATATCTAAGAACTTTTGCCACTGTGACTAATGGTCCTAATATTAAGCTGTTGTTTATATTTATCATATATCTATGGCTACATGGTTATATTA
TGCTGTGGTTGCGTTCGGTTTTATTTACAGTTGCTTTTACAAATATTTGCTGTAACATTTGACTTCTAAGGTTTAGATGCCATTTAAGAACTGAGATGGA
TAGCTTTTAAAGCATCTTTTACTTCTTACCATTTTTTAAAAGTATGCAGCTAAATTCGAAGCTTTTGGTCTATATTGTTAATTGCCATTGCTGTAAATCT
TAAAATGAATGAATAAAAATGTTTCATTTTACAA
  • refseq_TLR8.F1 (forward primer)
  • refseq_TLR8.R1 (reverse primer)
  • Single exon skipping

Frame 0

LLHRGYHSALLQVTE*KIRTTETWFS*HFSVRE
HQQDPSQETLKEAFERENEGVIFAK*LLQPGKGD
*KGKHVPSVVNADLHFPANIWFL*VMRRRKFF*
KLSL**EKAK*LSYCRVQQSSTTGSSPNGGQIC
DRTRPV**FHHTHNE*IISRAAKSH*NKSKPQPQ
CTAPERKSRYTIKWLEYHRRGIPQPKKPKGVTA
*RQPVTPNTLWFARVFDRT*SNSKQYIQHN*RG
HFKTYKLEKSLFGLELLF*QSLREN*HRRWSI*N
ADKFGVAITIFQFSFTRATQTAKLPTQTFSEQH
PDQIH**RRFQGIDKFNITRFKRELSEVLQCPI
SMRAL*WWCFN*YRSFCFSKLDPTSIPKPL*HFP
QED*CCLV*KYASSEGAGS*IQLFSGRNSLWGI
FNDAAPLRNT*LVF*LYKGELSTAY*YFQKLL*
TFVSTGIAFKRLCVPGTQRR*FPAPDAASKLIDY
QLGY*FY*ANRFQTFPKFLQSGNYLLVRKQNIT
VGKRYPAELCK*FLFSTSYPETTLNRF*V*PTF
ELLSFHPSFNKATMCCLWKSLRFKPQQYFLHWAK
PI*KSS*HCLFKSVCK*QCSSVKWN*IFSHSSC
QIFGFDKQ*TRL**C*CSY*IVRLGSSRSQL*F
TLFQNSRRNTSSRIYSKFHKSKSFKLEPQQHLYF
NR*V*PGKQVPGRISFQWQSP*HFVE***QQVY
LHFQRSQESDTSGFIP**AEAHPK*SIP*FASE
SH*TTYK**YVKVF*LDITPAVSSSRVA*LTWKQ
TTLFN**PI*LYIFPSDTAAES*QDFPPTLWLS
F*SQ*SEAPRFKFQSAKNNQQIRT*N*DHHQII
YVGTTRKPL*MHL*HWRFPKMDG*TSECQNSQTG
RCHLCQSWGSKREEYCESGANNLCFRCHCSDII
FLHVLYHHHGYVGCPGSPFVLLGCLVYI*CVFS
*GKRLQVSFHIPNFL*CLHFL*HQRCLCY*LGDK
*AALPP*REPRQKRSPLSRGEGLGSGIGHHRQP
HAEHQPKQENSICFNQKICKKLEL*NSFLLGFA
EANG*EHGCDYIYPAGASVTAFSVFEATAADL*E
LHPPVA*QPEGRRLVLANSEKCGLD*K*FTV*Q
YVCRFH*AILTDVKS*FRAIIKMQRNDISVLVI
YCYVTNYPKT*WFKTTHLLAHSF*GSGVQAQHNW
VLCSGCLRGCNVGVHQRHRHHWGHTHVVVFWIQ
FLLGYWPKAILM*AMRASPTRQLASSELAKKRG
C*QDEVTIFCNRIKKVISHHFGHILFVRSKPQVP
PAPWE*PPQSRENS*RPRW*ALIASVGHQLFSL
DCCPGMACYLDDRL*ISGGRDHCGPS*QLT*HI
FFSISKNFCHCD*WS*Y*AVVYIYHISMATWLYY
AVVAFGFIYSCFYKYLL*HLTSKV*MPFKN*DG
*LLKHLLLLTIF*KYAAKFEAFGLYC*LPLL*I
LK*MNKNVSFY

Frame 1

SCIEGTILRCCKLRNEKLEQQKHGSLDTSVLGN
ISKTHPRRP*RKPLKGRMKESSLQNSSCSLGKE
TKKENMFLQSSMLTCIFLLISGSCELCAEENFSR
SYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYV
TELDLSDNFITHITNESFQGLQNLTKINLNHNP
NVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLL
EDNQLPQIPSGLPESLTELSLIQNNIYNITKEG
ISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFE
TLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNT
QIKYISEEDFKGLINLTLLDLSGNCPRCFNAPF
PCVPCDGGASINIDRFAFQNLTQLRYLNLSSTS
LRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAF
LTMLPRLEILDLSFNYIKGSYPQHINISRNFSK
LLSLRALHLRGYVFQELREDDFQPLMQLPNLST
INLGINFIKQIDFKLFQNFSNLEIIYLSENRISP
LVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHS
NFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGP
NQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV
KYLDLTNNRLDFDNASALTELSDLEVLDLSYNS
HYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYT
LTDKYNLESKSLVELVFSGNRLDILWNDDDNRYI
SIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPAS
LTELHINDNMLKFFNWTLLQQFPRLELLDLRGN
KLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFL
SEVSSLKHLDLSSNLLKTINKSALETKTTTKLS
MLELHGNPFECTCDIGDFRRWMDEHLNVKIPRL
VDVICASPGDQRGKSIVSLELTTCVSDVTAVILF
FFTFFITTMVMLAALAHHLFYWDVWFIYNVCLA
KVKGYRSLSTSQTFYDAYISYDTKDASVTDWVI
NELRYHLEESRDKNVLLCLEERDWDPGLAIIDNL
MQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQ
RLMDENMDVIIFILLEPVLQHSQYLRLRQRICK
SSILQWPDNPKAEGLFWQTLRNVVLTENDSRYNN
MYVDSIKQY*LTLSHDFAP**RCKGMTFLY*LS
IAM*QIIPKLSGLKQHICWPTVFEGQESRPSIT
GSSAQGVSEAAM*VFTRDIGITGVTLMWLFSGFN
SSWAIGQRLYSCKPCEPLPQGSLLHQS*QKREV
ASKMKSQSFVIESKK*YLITLAIFYLLEVNHRS
HQLHGSDHLSPGKTAEDQDGEL*LLQLVINYFPL
TAVLGWPAILMIDCEYQEAGITVDHLSS*PNTS
SFQYLRTFATVTNGPNIKLLFIFIIYLWLHGYI
MLWLRSVLFTVAFTNICCNI*LLRFRCHLRTEMD
SF*SIFYFLPFFKSMQLNSKLLVYIVNCHCCKS
*NE*IKMFHFT

Frame 2

PA*RVPFCAAASYGMKN*NNRNMVLLTLQC*GT
SARPIPGDLEGSL*KGE*RSHLCKIAPAAWERR
LKRKTCSFSRQC*PAFSC*YLVPVSYAPKKIFL
EAILVMRKSKMTQLLQSAAIVDYRKFPKRWANM*
QN*TCLIISSHT*RMNHFKGCKISLK*I*TTTP
MYSTRTEIPVYNQMA*ISQTGHSST*KT*GSYC
LKTTSYPKYPLVCQSL*QNLV*FKTIYTT*LKRA
FQDL*T*KISIWPGTAILTKFARKLT*KMEYLK
R*QIWSCYHYLSILFHTCHPNCQAPYANFF*AT
PRSNTLVKKISRD**I*HY*I*AGTVRGASMPHF
HACLVMVVLQLI*IVLLFKT*PNFDT*TSLALP
SGRLMLPGLKICLI*RCWILNSTI*WEK*PLGH
F*RCCPA*KYLTCLLTI*RGVIHSILIFPETSLN
FCLYGHCI*EVMCSRNSEKMISSP*CSFQTYRL
STWVLILLSKSISNFSKISPIWKLFTCQKTEYH
RW*KIPGRVMQIVPLFNVISGNDAQQILSLTHIR
TFIISPVL**SHNVLLMEKP*I*ASTVFSSLGQ
TNLKIFLTLPV*ICLQIAMLKC*VELNFQPFLM
SNIWI*QTID*TLIMLVLLLNCPTWKF*ISAIIH
TISE*QA*HII*NLFKISQI*KF*T*ATTTFIL
*QISITWKASPW*N*FSVAIALTFCGMMMTTGI
SPFSKVSRI*HVWIYPLIG*STSQMKHSLICQRV
SLNYI*MIIC*SFLTGHYSSSFLVSSCLTYVET
NYSF*LIAYLTLHLPFGHCC*VITGFPTYPLAF
FLKSVV*STSI*VPIC*KQSTNPHLKLRPPPNYL
CWNYTETPLNAPVTLEISEDGWMNI*MSKFPDW
*MSFVPVLGIKEGRVL*VWS*QLVFQMSLQ*YY
FSSRSLSPPWLCWLPWLTICFTGMFGLYIMCV*L
R*KATGLFPHPKLSMMLTFLMTPKMPLLLTG**
MSCATTLKRAETKTFSFV*RRGIGIRDWPSSTT
SCRASTKARKQYLF*PKNMQKAGTLKQLFTWLCR
G*WMRTWM*LYLSCWSQCYSILSI*GYGSGSVR
APSSSGLTTRRQKACFGKL*EMWS*LKMIHGIT
ICMSIPLSNTN*R*VMISRHNKDAKE*HFCISYL
LLCNKLSQNLVV*NNTFAGPQFLRVRSPGPA*L
GPLLRVSQRLQCRCSPET*ASLGSHSCGCFLDS
IPPGLLAKGYTHVSHASLSHKAACFIRASKKERL
LAR*SHNLL*SNQKSDISSLWPYSIC*K*TTGP
TSSMGVTTSVQGKQLKTKMVSSDCFSWSSTIFP
*LLSWDGLLS***IVNIRRQGSLWTILAVDLTHL
LFNI*ELLPL*LMVLILSCCLYLSYIYGYMVIL
CCGCVRFYLQLLLQIFAVTFDF*GLDAI*ELRW
IAFKASFTSYHFLKVCS*IRSFWSILLIAIAVNL
KMNE*KCFILQ

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