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Sequences

Sequence NM_030593

GTGTTGTACGAAAGCGCGTCTGCGGCCGCAATGTCTGCTGAGAGTTGTAGTTCTGTGCCCTATCACGGCCACTCCCATTTCTGGTGCCGTCACGGGACAG AGCAGTCGGTGACAGGACAGAGCAGTCGGTGACGGGACACAGTGGTTGGTGACGGGACAGAGCGGTCGGTGACAGCCTCAAGGGCTTCAGCACCGCGCCC ATGGCAGAGCCAGACCGACTCAGATTCAGACTCTGAGGGAGGAGCCGCTGGTGGAGAAGCAGACATGGACTTCCTGCGGAACTTATTCTCCCAGACGCTC AGCCTGGGCAGCCAGAAGGAGCGTCTGCTGGACGAGCTGACCTTGGAAGGGGTGGCCCGGTACATGCAGAGCGAACGCTGTCGCAGAGTCATCTGTTTGG TGGGAGCTGGAATCTCCACATCCGCAGGCATCCCCGACTTTCGCTCTCCATCCACCGGCCTCTATGACAACCTAGAGAAGTACCATCTTCCCTACCCAGA GGCCATCTTTGAGATCAGCTATTTCAAGAAACATCCGGAACCCTTCTTCGCCCTCGCCAAGGAACTCTATCCTGGGCAGTTCAAGCCAACCATCTGTCAC TACTTCATGCGCCTGCTGAAGGACAAGGGGCTACTCCTGCGCTGCTACACGCAGAACATAGATACCCTGGAGCGAATAGCCGGGCTGGAACAGGAGGACT TGGTGGAGGCGCACGGCACCTTCTACACATCACACTGCGTCAGCGCCAGCTGCCGGCACGAATACCCGCTAAGCTGGATGAAAGAGAAGATCTTCTCTGA GGTGACGCCCAAGTGTGAAGACTGTCAGAGCCTGGTGAAGCCTGATATCGTCTTTTTTGGTGAGAGCCTCCCAGCGCGTTTCTTCTCCTGTATGCAGTCA GACTTCCTGAAGGTGGACCTCCTCCTGGTCATGGGTACCTCCTTGCAGGTGCAGCCCTTTGCCTCCCTCATCAGCAAGGCACCCCTCTCCACCCCTCGCC TGCTCATCAACAAGGAGAAAGCTGGCCAGTCGGACCCTTTCCTGGGGATGATTATGGGCCTCGGAGGAGGCATGGACTTTGACTCCAAGAAGGCCTACAG GGACGTGGCCTGGCTGGGTGAATGCGACCAGGGCTGCCTGGCCCTTGCTGAGCTCCTTGGATGGAAGAAGGAGCTGGAGGACCTTGTCCGGAGGGAGCAC GCCAGCATAGATGCCCAGTCGGGGGCGGGGGTCCCCAACCCCAGCACTTCAGCTTCCCCCAAGAAGTCCCCGCCACCTGCCAAGGACGAGGCCAGGACAA CAGAGAGGGAGAAACCCCAGTGACAGCTGCATCTCCCAGGCGGGATGCCGAGCTCCTCAGGGACAGCTGAGCCCCAACCGGGCCTGGCCCCCTCTTAACC AGCAGTTCTTGTCTGGGGAGCTCAGAACATCCCCCAATCTCTTACAGCTCCCTCCCCAAAACTGGGGTCCCAGCAACCCTGGCCCCCAACCCCAGCAAAT CTCTAACACCTCCTAGAGGCCAAGGCTTAAACAGGCATCTCTACCAGCCCCACTGTCTCTAACCACTCCTGGGCTAAGGAGTAACCTCCCTCATCTCTAA CTGCCCCCACGGGGCCAGGGCTACCCCAGAACTTTTAACTCTTCCAGGACAGGGAGCTTCGGGCCCCCACTCTGTCTCCTGCCCCCGGGGGCCTGTGGCT AAGTAAACCATACCTAACCTACCCCAGTGTGGGTGTGGGCCTCTGAATATAACCCACACCCAGCGTAGGGGGAGTCTGAGCCGGGAGGGCTCCCGAGTCT CTGCCTTCAGCTCCCAAAGTGGGTGGTGGGCCCCCTTCACGTGGGACCCACTTCCCATGCTGGATGGGCAGAAGACATTGCTTATTGGAGACAAATTAAA AACAAAAACAACTAACAA

refseq_SIRT2.F1 (forward primer)
refseq_SIRT2.R1 (reverse primer)
Single exon skipping

Frame 0

VLYESASAAAMSAESCSSVPYHGHSHFWCRHGT EQSVTGQSSR*RDTVVGDGTERSVTASRASAPRP WQSQTDSDSDSEGGAAGGEADMDFLRNLFSQTL SLGSQKERLLDELTLEGVARYMQSERCRRVICL VGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPE AIFEISYFKKHPEPFFALAKELYPGQFKPTICH YFMRLLKDKGLLLRCYTQNIDTLERIAGLEQED LVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSE VTPKCEDCQSLVKPDIVFFGESLPARFFSCMQS DFLKVDLLLVMGTSLQVQPFASLISKAPLSTPR LLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYR DVAWLGECDQGCLALAELLGWKKELEDLVRREH ASIDAQSGAGVPNPSTSASPKKSPPPAKDEART TEREKPQ*QLHLPGGMPSSSGTAEPQPGLAPS*P AVLVWGAQNIPQSLTAPSPKLGSQQPWPPTPAN L*HLLEAKA*TGISTSPTVSNHSWAKE*PPSSL TAPTGPGLPQNF*LFQDRELRAPTLSPAPGGLWL SKPYLTYPSVGVGL*I*PTPSVGGV*AGRAPES LPSAPKVGGGPPSRGTHFPCWMGRRHCLLETN* KQKQLT

Frame 1

CCTKARLRPQCLLRVVVLCPITATPISGAVTGQ SSR*QDRAVGDGTQWLVTGQSGR*QPQGLQHRA HGRARPTQIQTLREEPLVEKQTWTSCGTYSPRRS AWAARRSVCWTS*PWKGWPGTCRANAVAESSVW WELESPHPQASPTFALHPPASMTT*RSTIFPTQ RPSLRSAISRNIRNPSSPSPRNSILGSSSQPSVT TSCAC*RTRGYSCAATRRT*IPWSE*PGWNRRT WWRRTAPSTHHTASAPAAGTNTR*AG*KRRSSL R*RPSVKTVRAW*SLISSFLVRASQRVSSPVCSQ TS*RWTSSWSWVPPCRCSPLPPSSARHPSPPLA CSSTRRKLASRTLSWG*LWASEEAWTLTPRRPT GTWPGWVNATRAAWPLLSSLDGRRSWRTLSGGST PA*MPSRGRGSPTPALQLPPRSPRHLPRTRPGQ QRGRNPSDSCISQAGCRAPQGQLSPNRAWPPLN QQFLSGELRTSPNLLQLPPQNWGPSNPGPQPQQI SNTS*RPRLKQASLPAPLSLTTPGLRSNLPHL* LPPRGQGYPRTFNSSRTGSFGPPLCLLPPGACG *VNHT*PTPVWVWASEYNPHPA*GESEPGGLPSL CLQLPKWVVGPLHVGPTSHAGWAEDIAYWRQIK NKNN*Q

Frame 2

VVRKRVCGRNVC*EL*FCALSRPLPFLVPSRDR AVGDRTEQSVTGHSGW*RDRAVGDSLKGFSTAP MAEPDRLRFRL*GRSRWWRSRHGLPAELILPDA QPGQPEGASAGRADLGRGGPVHAERTLSQSHLFG GSWNLHIRRHPRLSLSIHRPL*QPREVPSSLPR GHL*DQLFQETSGTLLRPRQGTLSWAVQANHLS LLHAPAEGQGATPALLHAEHRYPGANSRAGTGGL GGGARHLLHITLRQRQLPARIPAKLDEREDLL* GDAQV*RLSEPGEA*YRLFW*EPPSAFLLLYAV RLPEGGPPPGHGYLLAGAALCLPHQQGTPLHPSP AHQQGESWPVGPFPGDDYGPRRRHGL*LQEGLQ GRGLAG*MRPGLPGPC*APWMEEGAGGPCPEGA RQHRCPVGGGGPQPQHFSFPQEVPATCQGRGQDN REGETPVTAASPRRDAELLRDS*APTGPGPLLT SSSCLGSSEHPPISYSSLPKTGVPATLAPNPSK SLTPPRGQGLNRHLYQPHCL*PLLG*GVTSLISN CPHGARATPELLTLPGQGASGPHSVSCPRGPVA K*TIPNLPQCGCGPLNITHTQRRGSLSREGSRV SAFSSQSGWWAPFTWDPLPMLDGQKTLLIGDKLK TKTTN

Sequence NM_012237

GTGTTGTACGAAAGCGCGTCTGCGGCCGCAATGTCTGCTGAGAGTTGTAGTTCTGTGCCCTATCACGGCCACTCCCATTTCTGGTGCCGTCACGGGACAG AGCAGTCGGTGACAGGACAGAGCAGTCGGTGACGGGACACAGTGGTTGGTGACGGGACAGAGCGGTCGGTGACAGCCTCAAGGGCTTCAGCACCGCGCCC ATGGCAGAGCCAGACCCCTCTCACCCTCTGGAGACCCAGGCAGGGAAGGTGCAGGAGGCTCAGGACTCAGATTCAGACTCTGAGGGAGGAGCCGCTGGTG GAGAAGCAGACATGGACTTCCTGCGGAACTTATTCTCCCAGACGCTCAGCCTGGGCAGCCAGAAGGAGCGTCTGCTGGACGAGCTGACCTTGGAAGGGGT GGCCCGGTACATGCAGAGCGAACGCTGTCGCAGAGTCATCTGTTTGGTGGGAGCTGGAATCTCCACATCCGCAGGCATCCCCGACTTTCGCTCTCCATCC ACCGGCCTCTATGACAACCTAGAGAAGTACCATCTTCCCTACCCAGAGGCCATCTTTGAGATCAGCTATTTCAAGAAACATCCGGAACCCTTCTTCGCCC TCGCCAAGGAACTCTATCCTGGGCAGTTCAAGCCAACCATCTGTCACTACTTCATGCGCCTGCTGAAGGACAAGGGGCTACTCCTGCGCTGCTACACGCA GAACATAGATACCCTGGAGCGAATAGCCGGGCTGGAACAGGAGGACTTGGTGGAGGCGCACGGCACCTTCTACACATCACACTGCGTCAGCGCCAGCTGC CGGCACGAATACCCGCTAAGCTGGATGAAAGAGAAGATCTTCTCTGAGGTGACGCCCAAGTGTGAAGACTGTCAGAGCCTGGTGAAGCCTGATATCGTCT TTTTTGGTGAGAGCCTCCCAGCGCGTTTCTTCTCCTGTATGCAGTCAGACTTCCTGAAGGTGGACCTCCTCCTGGTCATGGGTACCTCCTTGCAGGTGCA GCCCTTTGCCTCCCTCATCAGCAAGGCACCCCTCTCCACCCCTCGCCTGCTCATCAACAAGGAGAAAGCTGGCCAGTCGGACCCTTTCCTGGGGATGATT ATGGGCCTCGGAGGAGGCATGGACTTTGACTCCAAGAAGGCCTACAGGGACGTGGCCTGGCTGGGTGAATGCGACCAGGGCTGCCTGGCCCTTGCTGAGC TCCTTGGATGGAAGAAGGAGCTGGAGGACCTTGTCCGGAGGGAGCACGCCAGCATAGATGCCCAGTCGGGGGCGGGGGTCCCCAACCCCAGCACTTCAGC TTCCCCCAAGAAGTCCCCGCCACCTGCCAAGGACGAGGCCAGGACAACAGAGAGGGAGAAACCCCAGTGACAGCTGCATCTCCCAGGCGGGATGCCGAGC TCCTCAGGGACAGCTGAGCCCCAACCGGGCCTGGCCCCCTCTTAACCAGCAGTTCTTGTCTGGGGAGCTCAGAACATCCCCCAATCTCTTACAGCTCCCT CCCCAAAACTGGGGTCCCAGCAACCCTGGCCCCCAACCCCAGCAAATCTCTAACACCTCCTAGAGGCCAAGGCTTAAACAGGCATCTCTACCAGCCCCAC TGTCTCTAACCACTCCTGGGCTAAGGAGTAACCTCCCTCATCTCTAACTGCCCCCACGGGGCCAGGGCTACCCCAGAACTTTTAACTCTTCCAGGACAGG GAGCTTCGGGCCCCCACTCTGTCTCCTGCCCCCGGGGGCCTGTGGCTAAGTAAACCATACCTAACCTACCCCAGTGTGGGTGTGGGCCTCTGAATATAAC CCACACCCAGCGTAGGGGGAGTCTGAGCCGGGAGGGCTCCCGAGTCTCTGCCTTCAGCTCCCAAAGTGGGTGGTGGGCCCCCTTCACGTGGGACCCACTT CCCATGCTGGATGGGCAGAAGACATTGCTTATTGGAGACAAATTAAAAACAAAAACAACTAACAA

refseq_SIRT2.F1 (forward primer)
refseq_SIRT2.R1 (reverse primer)
Single exon skipping

Frame 0

VLYESASAAAMSAESCSSVPYHGHSHFWCRHGT EQSVTGQSSR*RDTVVGDGTERSVTASRASAPRP WQSQTPLTLWRPRQGRCRRLRTQIQTLREEPLV EKQTWTSCGTYSPRRSAWAARRSVCWTS*PWKG WPGTCRANAVAESSVWWELESPHPQASPTFALHP PASMTT*RSTIFPTQRPSLRSAISRNIRNPSSP SPRNSILGSSSQPSVTTSCAC*RTRGYSCAATR RT*IPWSE*PGWNRRTWWRRTAPSTHHTASAPAA GTNTR*AG*KRRSSLR*RPSVKTVRAW*SLISS FLVRASQRVSSPVCSQTS*RWTSSWSWVPPCRC SPLPPSSARHPSPPLACSSTRRKLASRTLSWG*L WASEEAWTLTPRRPTGTWPGWVNATRAAWPLLS SLDGRRSWRTLSGGSTPA*MPSRGRGSPTPALQ LPPRSPRHLPRTRPGQQRGRNPSDSCISQAGCRA PQGQLSPNRAWPPLNQQFLSGELRTSPNLLQLP PQNWGPSNPGPQPQQISNTS*RPRLKQASLPAP LSLTTPGLRSNLPHL*LPPRGQGYPRTFNSSRTG SFGPPLCLLPPGACG*VNHT*PTPVWVWASEYN PHPA*GESEPGGLPSLCLQLPKWVVGPLHVGPT SHAGWAEDIAYWRQIKNKNN*Q

Frame 1

CCTKARLRPQCLLRVVVLCPITATPISGAVTGQ SSR*QDRAVGDGTQWLVTGQSGR*QPQGLQHRA HGRARPLSPSGDPGREGAGGSGLRFRL*GRSRWW RSRHGLPAELILPDAQPGQPEGASAGRADLGRG GPVHAERTLSQSHLFGGSWNLHIRRHPRLSLSI HRPL*QPREVPSSLPRGHL*DQLFQETSGTLLRP RQGTLSWAVQANHLSLLHAPAEGQGATPALLHA EHRYPGANSRAGTGGLGGGARHLLHITLRQRQL PARIPAKLDEREDLL*GDAQV*RLSEPGEA*YRL FW*EPPSAFLLLYAVRLPEGGPPPGHGYLLAGA ALCLPHQQGTPLHPSPAHQQGESWPVGPFPGDD YGPRRRHGL*LQEGLQGRGLAG*MRPGLPGPC*A PWMEEGAGGPCPEGARQHRCPVGGGGPQPQHFS FPQEVPATCQGRGQDNREGETPVTAASPRRDAE LLRDS*APTGPGPLLTSSSCLGSSEHPPISYSSL PKTGVPATLAPNPSKSLTPPRGQGLNRHLYQPH CL*PLLG*GVTSLISNCPHGARATPELLTLPGQ GASGPHSVSCPRGPVAK*TIPNLPQCGCGPLNIT HTQRRGSLSREGSRVSAFSSQSGWWAPFTWDPL PMLDGQKTLLIGDKLKTKTTN

Frame 2

VVRKRVCGRNVC*EL*FCALSRPLPFLVPSRDR AVGDRTEQSVTGHSGW*RDRAVGDSLKGFSTAP MAEPDPSHPLETQAGKVQEAQDSDSDSEGGAAG GEADMDFLRNLFSQTLSLGSQKERLLDELTLEGV ARYMQSERCRRVICLVGAGISTSAGIPDFRSPS TGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFA LAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQ NIDTLERIAGLEQEDLVEAHGTFYTSHCVSASC RHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIV FFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQ PFASLISKAPLSTPRLLINKEKAGQSDPFLGMI MGLGGGMDFDSKKAYRDVAWLGECDQGCLALAE LLGWKKELEDLVRREHASIDAQSGAGVPNPSTSA SPKKSPPPAKDEARTTEREKPQ*QLHLPGGMPS SSGTAEPQPGLAPS*PAVLVWGAQNIPQSLTAP SPKLGSQQPWPPTPANL*HLLEAKA*TGISTSPT VSNHSWAKE*PPSSLTAPTGPGLPQNF*LFQDR ELRAPTLSPAPGGLWLSKPYLTYPSVGVGL*I* PTPSVGGV*AGRAPESLPSAPKVGGGPPSRGTHF PCWMGRRHCLLETN*KQKQLT