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Sequences

Sequence NM_198554

AGTCGACCGTGGACCGCGCTGCGAGCCTCGGAGACGCCGTAGAAGGAGACCTGCTTCCGGGACTGGACCAGGCGCCTGCGACTCTTCTCAGACGCCGACG TGCACGAGTGACTACTATTAATTCTATTTAAAATGGGTGTAAAGAAGAAGAAAGAAATGCAAGTTGCTGCGCTGACCATTTGCCATCAGGACCTTGAAAC TTTGAAATCTTTTGCTGATGTGGAAGGGAAAAATCTAGCTTCTTTGCTGTTACATTGTGTGCAACTCACGGATGGAGTGTCACAAATCCATTATATTAAA CAGATTGTGCCTCTGCTGGAGAAAGCAGATAAAAATGGCATGTGTGATCCCACTATTCAAAGTTGTTTGGATATCTTAGCAGGCATTTATCTTTCTTTGA GTCTAAAGAATCCCTTGAAGAAAGTATTGGCAAGCTCACTAAATAGCCTGCCTGATTTTTTTCTACCTGAGGCTATGCACCGTTTTACTTCTCGTCTTCA GGAAGAATTGAATACTACTGACTTATACTCTTACAGGAAAGTTACTGACAATATTTCTTCCTGTATGGAGAACTTTAACTTGGGTAGAGCAAGTGTTAAT AATCTGCTTAAAAATGTGCTTCATTTTCTGCAGAAGAGTTTAATTGAAATCCTGGAAGAAAATAGAAAATGTGCTGGAAATCATATTATTCAAACACAGT TGATGAATGACTTACTGGTAGGCATTAGAGTTTCAATGATGTTAGTACAGAAAGTACAAGATTTCCAGGGAAATCTTTGGAAGACTTCCGATTCTCCCAT ATGGCAAAATATGTGTGGATTGCTGAGTATTTTTACCAAGGTTTTAAGCGATGATGATCTGTTACAGACTGTACAGAGCACATCTGGATTAGCTATTATT CTTTTTATTAAGACTATGTTTCACCCGTCTGAAAAGATTCCTCATTTGTGTGCTGCTTCGTTCAGTGGACTGCACCAGTGTCCCCGAGTGGTTTATGAGC AGCTGCAGGAGCCTCTGTTGTGGTGACATCTCTCAGTCAGCTGTCTTATTCCTCTGTCAGGGGACACTTGCCATGTTGGACTGGCAGAACGGAAGCATGG GTCGGAGTGGGGAGGCCCTGCTCTTGGATACTGCACATGTTTTGTTCACCTTGAGTTCACAGATTAAAGAGCCAACGCTGGAAATGTTTCTGTCTAGAAT CTTAGCATCCTGGACTAATTCAGCCATACAAGTCCTTGAATCAAGTTCCCCGAGCCTAACGGACAGCCTGAATGGGAATTCAAGTATAGTTGGGAGACTT TTGGAATATGTCTATACCCATTGGGAACATCCATTGGATGCTCTGAGACACCAAACCAAAATCATGTTCAAAAACCTTCTCCAAATGCACCGGCTCACTG TGGAAGGTGCAGATTTCGTCCCTGATCCTTTCTTTGTGGAATTGACTGAGAGTCTTTTACGATTGGAATGGCATATTAAAGGAAAGTACACGTGCCTTGG TTGTTTGGTAGAGTGCATAGGAGTTGAACATATTTTGGCTATAGATAAAACTATTCCATCTCAAATCTTAGAGGTGATGGGAGACCAGTCATTGGTACCT TATGCAAGTGACCTCTTGGAAACCATGTTTAGAAATCATAAGAGTCATTTGAAATCCCAGACTGCTGAGAGTTCTTGGATTGACCAGTGGCATGAGACTT GGGTTTCTCCTCTCCTTTTTATATTGTGTGAAGGAAACTTGGATCAAAAATCTTACGTGATTGATTATTACTTGCCAAAATTATTAAGTTACAGCCCTGA AAGCTTACAGTACATGGTAAAGATTCTTCAGACTTCTATTGATGCTAAAACTGGACAAGAGCAATCTTTCCCATCCTTAGGGTCTTGTAATAGCAGGGGG GCTCTGGGAGCTTTGATGGCATGTCTGCGAATAGCTAGAGCTCATGGACATCTTCAGTCTGCAACTGATACCTGGGAGAACCTCGTGTCTGATGCAAGAA TAAAGCAAGGCTTAATTCATCAGCATTGCCAAGTAAGGATAGATACATTAGGCTTGCTTTGTGAAAGTAATCGGAGCACAGAAATTGTTTCCATGGAAGA AATGCAGTGGATTCAGTTCTTTATTACATACAATCTTAACAGCCAGTCTCCAGGAGTGCGGCAACAGATCTGTTCTCTTCTTAAAAAGTTGTTTTGTAGG ATACAGGAAAGTTCTCAGGTACTTTATAAATTGGAGCAGAGTAAATCCAAACGTGAACCAGAGAATGAGTTAACCAAACAGCACCCTTCTGTTTCTTTAC AGCAGTATAAGAATTTCATGTCATCCATTTGTAACAGTCTTTTTGAAGCATTGTTTCCTGGATCTTCCTACTCGACTAGATTTTCAGCTTTAACCATTTT AGGTTCAATAGCTGAAGTTTTTCATGTCCCAGAAGGCAGAATTTATACAGTATATCAGCTGAGTCATGATATTGATGTTGGTCGTTTCCAAACACTAATG GAATGTTTTACCAGCACTTTTGAAGACGTGAAAATTTTAGCATTTGATCTTCTGATGAAGTTATCAAAAACAGCTGTACATTTTCAGGATTCGGGGAAAC TGCAAGGCTTATTTCAGGCAGCATTGGAGCTCAGCACAAGCACCAAACCATACGACTGTGTGACAGCTTCCTACCTGCTGAACTTCTTAATCTGGCAGGA TGCTCTACCGTCATCCTTGTCTGCCTACTTAACTCAGCAAGTTGCATGTGATAATGGAGATAGGCCTGCTGCTGTGGTGGAAAGGAACACATTAATGGTT ATCAAATGCTTGATGGAAAATCTTGAGGAAGAAGTATCTCAGGCTGAAAATTCTCTGCTTCAGGCAGCAGCAGCATTTCCAATGTATGGGCGAGTCCACT GTATAACAGGAGCTTTGCAGAAGTTATCTCTAAACAGCCTGCAGTTGGTGAGCGAGTGGAGACCTGTGGTAGAGAAGCTCCTTTTGATGTCCTACAGGCT TTCCACTGTGGTGTCTCCAGTCATTCAGAGCTCATCCCCTGAAGGCCTCATCCCAATGGACACTGATTCAGAGTCAGCAAGCCGCTTACAGATGATTCTG AATGAGATTCAGCCTCGAGATACTAATGATTATTTTAACCAAGCCAAAATATTGAAAGAACATGATAGCTTTGATATGAAGGACTTGAATGCTAGTGTGG TGAATATTGATACTTCTACAGAAATCAAAGGTAAAGAAGTAAAAACATGTGATGTAACTGCGCAGATGGTGCTGGTATGTTGTTGGAGAAGTATGAAGGA AGTTGCTTTACTTTTAGGCATGTTGTGCCAGCTTCTGCCCATGCAGCCTGTGCCAGAATCTTCTGATGGATTATTGACGGTGGAGCAGGTAAAAGAAATA GGAGATTACTTTAAACAACACCTTTTGCAGTCCAGGCACAGAGGAGCATTTGAATTGGCTTATACTGGTTTTGTGAAACTCACTGAAGTACTAAACAGGT GCCCAAATGTGAGTCTGCAAAAGCTGCCAGAACAGTGGCTATGGAGTGTTTTAGAGGAAATTAAATGCAGTGATCCTTCATCTAAACTCTGTGCTACAAG GCGCAGTGCTGGAATTCCTTTCTACATACAGGCACTGTTGGCATCTGAACCAAAGAAAGGCAGAATGGATTTGTTGAAAATAACAATGAAAGAGTTAATC TCTTTGGCTGGGCCTACAGATGACATACAGAGTACAGTCCCCCAGGTTCATGCTTTAAATATCCTTAGAGCATTGTTCAGAGATACGCGCCTGGGAGAAA ATATTATTCCTTATGTTGCTGATGGAGCTAAGGCTGCAATTCTGGGTTTTACATCACCGGTCTGGGCATGATATGGGAGAACCAAATCGTCATCCAAGCA TGTTTCTCTTACTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCATTATGAG GTGTGGTCACTCACCTGTCTACCACTCCCGTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTAATACCATTCGAACTCTG TTGTCCACACTCCCCAGCTGCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGTTTTTCATTTGTTGCAAGCCTACTCAGACT CCAAACACGGAACGAATTCAGACTTCCAGCACGAGCTGACTGACATCACTGTTTGTACCAAAGCCAAACTCTGGCTGGCCAAGAGGCAAAATCCATGTTT GGTGACCAGAGCTGTATATATTGATATTCTCTTCCTATTGACTTGCTGCCTCAACAGATCTGCAAAGGACAACCAGCCAGTTCTGGAGAGTCTTGGCTTC TGGGAGGAAGTCAGAGGGATTATCTCAGGATCAGAGCTGATAACGGGATTCCCTTGGGCCTTCAAGGTGCCAGGCCTGCCCCAGTACCTCCAGAGCCTCA CCAGACTAGCCATTGCTGCAGTGTGGGCCGCGGCAGCCAAGAGTGGAGAGCGGGAGACGAATGTCCCCATCTCTTTCTCTCAGCTGTTAGAATCTGCCTT CCCTGAAGTGCGCTCACTAACACTGGAAGCCCTCTTGGAAAAGTTCTTAGCAGCAGCCTCTGGACTTGGAGAGAAGGGCGTGCCACCCTTGCTGTGCAAC ATGGGAGAGAAGTTCTTATTGTTGGCCATGAAGGAAAATCACCCAGAATGCTTCTGCAAGATACTGAAAATTCTCCACTGCATGGACCCTGGTGAGTGGC TTCCCCAGACGGAGCACTGTGTCCATCTGACCCCAAAGGAGTTCTTGATCTGGACGATGGATATTGCTTCCAATGAAAGATCTGAAATTCAGAGTGTAGC TCTGAGACTTGCTTCCAAAGTCATTTCCCACCACATGCAGACATGTGTGGAGAACAGGGAATTGATAGCTGCTGAGCTGAAGCAGTGGGTTCAGCTGGTC ATCTTGTCATGTGAAGACCATCTTCCTACAGAGTCTAGGCTGGCCGTCGTTGAAGTCCTCACCAGTACTACACCACTTTTCCTCACCAACCCCCATCCTA TTCTTGAGTTGCAGGATACACTTGCTCTCTGGAAGTGTGTCCTTACCCTTCTGCAGAGTGAGGAGCAAGCTGTTAGAGATGCAGCCACGGAAACCGTGAC AACTGCCATGTCACAAGAAAATACCTGCCAGTCAACAGAGTTTGCCTTCTGCCAGGTGGATGCCTCCATCGCTCTGGCCCTGGCCCTGGCCGTCCTGTGT GATCTGCTCCAGCAGTGGGACCAGTTGGCCCCTGGACTGCCCATCCTGCTGGGATGGCTGTTGGGAGAGAGTGATGACCTCGTGGCCTGTGTGGAGAGCA TGCATCAGGTGGAAGAAGACTACCTGTTTGAAAAAGCAGAAGTCAACTTTTGGGCCGAGACCCTGATCTTTGTGAAATACCTCTGCAAGCACCTCTTCTG TCTCCTCTCAAAGTCCGGCTGGCGTCCCCCAAGCCCTGAGATGCTCTGTCACCTTCAAAGGATGGTGTCAGAGCAGTGCCACCTCCTGTCTCAGTTCTTC AGAGAGCTTCCACCAGCTGCTGAGTTTGTGAAGACAGTGGAGTTCACAAGACTACGCATTCAAGAGGAAAGGACTTTGGCTTGCTTGAGGCTGCTGGCCT TTTTGGAAGGAAAGGAAGGGGAAGACACCCTAGTTCTCAGTGTTTGGGACTCTTATGCAGAATCGAGGCAGTTAACTCTTCCAAGAACAGAAGCGGCATG TTGAAGAAAATCTGGGGGATTGGGATGGGGGTATGTGTGGATTTTTCCTCCACTAAATCTGCAGGAAACATGTTGAACATAAATTCAAAAATTTTATCCC

refseq_THADA.F2 (forward primer)
refseq_THADA.R2 (reverse primer)
Multiple exon skipping

Frame 0

SRPWTALRASETP*KETCFRDWTRRLRLFSDAD VHE*LLLILFKMGVKKKKEMQVAALTICHQDLET LKSFADVEGKNLASLLLHCVQLTDGVSQIHYIK QIVPLLEKADKNGMCDPTIQSCLDILAGIYLSL SLKNPLKKVLASSLNSLPDFFLPEAMHRFTSRLQ EELNTTDLYSYRKVTDNISSCMENFNLGRASVN NLLKNVLHFLQKSLIEILEENRKCAGNHIIQTQ LMNDLLVGIRVSMMLVQKVQDFQGNLWKTSDSPI WQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAII LFIKTMFHPSEKIPHLCAASFSGLHQCPRVVYE QLQEPLLW*HLSVSCLIPLSGDTCHVGLAERKHG SEWGGPALGYCTCFVHLEFTD*RANAGNVSV*N LSILD*FSHTSP*IKFPEPNGQPEWEFKYSWET FGICLYPLGTSIGCSETPNQNHVQKPSPNAPAHC GRCRFRP*SFLCGID*ESFTIGMAY*RKVHVPW LFGRVHRS*TYFGYR*NYSISNLRGDGRPVIGT LCK*PLGNHV*KS*ESFEIPDC*EFLD*PVA*DL GFSSPFYIV*RKLGSKILRD*LLLAKIIKLQP* KLTVHGKDSSDFY*C*NWTRAIFPILRVL**QG GSGSFDGMSANS*SSWTSSVCN*YLGEPRV*CKN KARLNSSALPSKDRYIRLAL*K*SEHRNCFHGR NAVDSVLYYIQS*QPVSRSAATDLFSS*KVVL* DTGKFSGTL*IGAE*IQT*TRE*VNQTAPFCFFT AV*EFHVIHL*QSF*SIVSWIFLLD*IFSFNHF RFNS*SFSCPRRQNLYSISAES*Y*CWSFPNTN GMFYQHF*RRENFSI*SSDEVIKNSCTFSGFGET ARLISGSIGAQHKHQTIRLCDSFLPAELLNLAG CSTVILVCLLNSASCM**WR*ACCCGGKEHING YQMLDGKS*GRSISG*KFSASGSSSISNVWASPL YNRSFAEVISKQPAVGERVETCGREAPFDVLQA FHCGVSSHSELIP*RPHPNGH*FRVSKPLTDDS E*DSASRY**LF*PSQNIERT**L*YEGLEC*CG EY*YFYRNQR*RSKNM*CNCADGAGMLLEKYEG SCFTFRHVVPASAHAACARIF*WIIDGGAGKRN RRLL*TTPFAVQAQRSI*IGLYWFCETH*STKQV PKCESAKAARTVAMECFRGN*MQ*SFI*TLCYK AQCWNSFLHTGTVGI*TKERQNGFVENNNERVN LFGWAYR*HTEYSPPGSCFKYP*SIVQRYAPGRK YYSLCC*WS*GCNSGFYITGLGMIWENQIVIQA CFSYFWCWRDSTLPRWMVLLLLSAWDLLFPSL* GVVTHLSTTPVKWQLVPWSHLL**ITFLIPFELC CPHSPAALTSVSGKTTFMGHFSRFFICCKPTQT PNTERIQTSSTS*LTSLFVPKPNSGWPRGKIHV W*PELYILIFSSY*LAASTDLQRTTSQFWRVLAS GRKSEGLSQDQS**RDSLGPSRCQACPSTSRAS PD*PLLQCGPRQPRVESGRRMSPSLSLSC*NLP SLKCAH*HWKPSWKSS*QQPLDLERRACHPCCAT WERSSYCWP*RKITQNASARY*KFSTAWTLVSG FPRRSTVSI*PQRSS*SGRWILLPMKDLKFRV* L*DLLPKSFPTTCRHVWRTGN**LLS*SSGFSWS SCHVKTIFLQSLGWPSLKSSPVLHHFSSPTPIL FLSCRIHLLSGSVSLPFCRVRSKLLEMQPRKP* QLPCHKKIPASQQSLPSARWMPPSLWPWPWPSCV ICSSSGTSWPLDCPSCWDGCWERVMTSWPVWRA CIRWKKTTCLKKQKSTFGPRP*SL*NTSASTSS VSSQSPAGVPQALRCSVTFKGWCQSSATSCLSSS ESFHQLLSL*RQWSSQDYAFKRKGLWLA*GCWP FWKERKGKTP*FSVFGTLMQNRGS*LFQEQKRH VEENLGDWDGGMCGFFLH*ICRKHVEHKFKNFI

Frame 1

VDRGPRCEPRRRRRRRPASGTGPGACDSSQTPT CTSDYY*FYLKWV*RRRKKCKLLR*PFAIRTLK L*NLLLMWKGKI*LLCCYIVCNSRMECHKSIILN RLCLCWRKQIKMACVIPLFKVVWIS*QAFIFL* V*RIP*RKYWQAH*IACLIFFYLRLCTVLLLVF RKN*ILLTYTLTGKLLTIFLPVWRTLTWVEQVLI ICLKMCFIFCRRV*LKSWKKIENVLEIILFKHS **MTYW*ALEFQ*C*YRKYKISREIFGRLPILP YGKICVDC*VFLPRF*AMMICYRLYRAHLD*LLF FLLRLCFTRLKRFLICVLLRSVDCTSVPEWFMS SCRSLCCGDISQSAVLFLCQGTLAMLDWQNGSM GRSGEALLLDTAHVLFTLSSQIKEPTLEMFLSRI LASWTNSAIQVLESSSPSLTDSLNGNSSIVGRL LEYVYTHWEHPLDALRHQTKIMFKNLLQMHRLT VEGADFVPDPFFVELTESLLRLEWHIKGKYTCLG CLVECIGVEHILAIDKTIPSQILEVMGDQSLVP YASDLLETMFRNHKSHLKSQTAESSWIDQWHET WVSPLLFILCEGNLDQKSYVIDYYLPKLLSYSPE SLQYMVKILQTSIDAKTGQEQSFPSLGSCNSRG ALGALMACLRIARAHGHLQSATDTWENLVSDAR IKQGLIHQHCQVRIDTLGLLCESNRSTEIVSMEE MQWIQFFITYNLNSQSPGVRQQICSLLKKLFCR IQESSQVLYKLEQSKSKREPENELTKQHPSVSL QQYKNFMSSICNSLFEALFPGSSYSTRFSALTIL GSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLM ECFTSTFEDVKILAFDLLMKLSKTAVHFQDSGK LQGLFQAALELSTSTKPYDCVTASYLLNFLIWQD ALPSSLSAYLTQQVACDNGDRPAAVVERNTLMV IKCLMENLEEEVSQAENSLLQAAAAFPMYGRVH CITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRL STVVSPVIQSSSPEGLIPMDTDSESASRLQMIL NEIQPRDTNDYFNQAKILKEHDSFDMKDLNASV VNIDTSTEIKGKEVKTCDVTAQMVLVCCWRSMKE VALLLGMLCQLLPMQPVPESSDGLLTVEQVKEI GDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNR CPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATR RSAGIPFYIQALLASEPKKGRMDLLKITMKELI SLAGPTDDIQSTVPQVHALNILRALFRDTRLGE NIIPYVADGAKAAILGFTSPVWA*YGRTKSSSKH VSLTFGVGETLRFPDGWYFFCSQHGTFCSLHYE VWSLTCLPLP*NGSSCLGPICYDRSHS*YHSNS VVHTPQLH*PVFPAKPHSWDTSPGFSFVASLLRL QTRNEFRLPARAD*HHCLYQSQTLAGQEAKSMF GDQSCIY*YSLPIDLLPQQICKGQPASSGESWL LGGSQRDYLRIRADNGIPLGLQGARPAPVPPEPH QTSHCCSVGRGSQEWRAGDECPHLFLSAVRICL P*SALTNTGSPLGKVLSSSLWTWREGRATLAVQ HGREVLIVGHEGKSPRMLLQDTENSPLHGPW*VA SPDGALCPSDPKGVLDLDDGYCFQ*KI*NSECS SETCFQSHFPPHADMCGEQGIDSC*AEAVGSAG HLVM*RPSSYRV*AGRR*SPHQYYTTFPHQPPSY S*VAGYTCSLEVCPYPSAE*GASC*RCSHGNRD NCHVTRKYLPVNRVCLLPGGCLHRSGPGPGRPV *SAPAVGPVGPWTAHPAGMAVGRE**PRGLCGEH ASGGRRLPV*KSRSQLLGRDPDLCEIPLQAPLL SPLKVRLASPKP*DALSPSKDGVRAVPPPVSVL QRASTSC*VCEDSGVHKTTHSRGKDFGLLEAAGL FGRKGRGRHPSSQCLGLLCRIEAVNSSKNRSGM LKKIWGIGMGVCVDFSSTKSAGNMLNINSKILS

Frame 2

STVDRAASLGDAVEGDLLPGLDQAPATLLRRRR ARVTTINSI*NGCKEEERNASCCADHLPSGP*N FEIFC*CGREKSSFFAVTLCATHGWSVTNPLY* TDCASAGESR*KWHV*SHYSKLFGYLSRHLSFFE SKESLEESIGKLTK*PA*FFST*GYAPFYFSSS GRIEYY*LILLQESY*QYFFLYGEL*LG*SKC* *SA*KCASFSAEEFN*NPGRK*KMCWKSYYSNTV DE*LTGRH*SFNDVSTESTRFPGKSLEDFRFSH MAKYVWIAEYFYQGFKR**SVTDCTEHIWISYY SFY*DYVSPV*KDSSFVCCFVQWTAPVSPSGL*A AAGASVVVTSLSQLSYSSVRGHLPCWTGRTEAW VGVGRPCSWILHMFCSP*VHRLKSQRWKCFCLE S*HPGLIQPYKSLNQVPRA*RTA*MGIQV*LGDF WNMSIPIGNIHWML*DTKPKSCSKTFSKCTGSL WKVQISSLILSLWN*LRVFYDWNGILKESTRAL VVW*SA*ELNIFWL*IKLFHLKS*R*WETSHWYL MQVTSWKPCLEIIRVI*NPRLLRVLGLTSGMRL GFLLSFLYCVKETWIKNLT*LIITCQNY*VTAL KAYSTW*RFFRLLLMLKLDKSNLSHP*GLVIAGG LWEL*WHVCE*LELMDIFSLQLIPGRTSCLMQE *SKA*FISIAK*G*IH*ACFVKVIGAQKLFPWK KCSGFSSLLHTILTASLQECGNRSVLFLKSCFVG YRKVLRYFINWSRVNPNVNQRMS*PNSTLLFLY SSIRISCHPFVTVFLKHCFLDLPTRLDFQL*PF *VQ*LKFFMSQKAEFIQYIS*VMILMLVVSKH*W NVLPALLKT*KF*HLIF**SYQKQLYIFRIRGN CKAYFRQHWSSAQAPNHTTV*QLPTC*TS*SGR MLYRHPCLPT*LSKLHVIMEIGLLLWWKGTH*WL SNA*WKILRKKYLRLKILCFRQQQHFQCMGEST V*QELCRSYL*TACSW*ASGDLW*RSSF*CPTG FPLWCLQSFRAHPLKASSQWTLIQSQQAAYR*F* MRFSLEILMIILTKPKY*KNMIALI*RT*MLVW *ILILLQKSKVKK*KHVM*LRRWCWYVVGEV*R KLLYF*ACCASFCPCSLCQNLLMDY*RWSR*KK* EITLNNTFCSPGTEEHLNWLILVL*NSLKY*TG AQM*VCKSCQNSGYGVF*RKLNAVILHLNSVLQ GAVLEFLSTYRHCWHLNQRKAEWIC*K*Q*KS*S LWLGLQMTYRVQSPRFML*ISLEHCSEIRAWEK ILFLMLLMELRLQFWVLHHRSGHDMGEPNRHPS MFLLLLVLERLYASPMDGTSSALSMGPFVPFIMR CGHSPVYHSREMAARALVPFVMIDHIPNTIRTL LSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYSD SKHGTNSDFQHELTDITVCTKAKLWLAKRQNPCL VTRAVYIDILFLLTCCLNRSAKDNQPVLESLGF WEEVRGIISGSELITGFPWAFKVPGLPQYLQSL TRLAIAAVWAAAAKSGERETNVPISFSQLLESAF PEVRSLTLEALLEKFLAAASGLGEKGVPPLLCN MGEKFLLLAMKENHPECFCKILKILHCMDPGEW LPQTEHCVHLTPKEFLIWTMDIASNERSEIQSVA LRLASKVISHHMQTCVENRELIAAELKQWVQLV ILSCEDHLPTESRLAVVEVLTSTTPLFLTNPHP ILELQDTLALWKCVLTLLQSEEQAVRDAATETVT TAMSQENTCQSTEFAFCQVDASIALALALAVLC DLLQQWDQLAPGLPILLGWLLGESDDLVACVES MHQVEEDYLFEKAEVNFWAETLIFVKYLCKHLFC LLSKSGWRPPSPEMLCHLQRMVSEQCHLLSQFF RELPPAAEFVKTVEFTRLRIQEERTLACLRLLA FLEGKEGEDTLVLSVWDSYAESRQLTLPRTEAAC *RKSGGLGWGYVWIFPPLNLQETC*T*IQKFYP

Sequence NM_022065

AGTCGACCGTGGACCGCGCTGCGAGCCTCGGAGACGCCGTAGAAGGAGACCTGCTTCCGGGACTGGACCAGGCGCCTGCGACTCTTCTCAGACGCCGACG TGCACGAGTGACTACTATTAATTCTATTTAAAATGGGTGTAAAGAAGAAGAAAGAAATGCAAGTTGCTGCGCTGACCATTTGCCATCAGGACCTTGAAAC TTTGAAATCTTTTGCTGATGTGGAAGGGAAAAATCTAGCTTCTTTGCTGTTACATTGTGTGCAACTCACGGATGGAGTGTCACAAATCCATTATATTAAA CAGATTGTGCCTCTGCTGGAGAAAGCAGATAAAAATGGCATGTGTGATCCCACTATTCAAAGTTGTTTGGATATCTTAGCAGGCATTTATCTTTCTTTGA GTCTAAAGAATCCCTTGAAGAAAGTATTGGCAAGCTCACTAAATAGCCTGCCTGATTTTTTTCTACCTGAGGCTATGCACCGTTTTACTTCTCGTCTTCA GGAAGAATTGAATACTACTGACTTATACTCTTACAGGAAAGTTACTGACAATATTTCTTCCTGTATGGAGAACTTTAACTTGGGTAGAGCAAGTGTTAAT AATCTGCTTAAAAATGTGCTTCATTTTCTGCAGAAGAGTTTAATTGAAATCCTGGAAGAAAATAGAAAATGTGCTGGAAATCATATTATTCAAACACAGT TGATGAATGACTTACTGGTAGGCATTAGAGTTTCAATGATGTTAGTACAGAAAGTACAAGATTTCCAGGGAAATCTTTGGAAGACTTCCGATTCTCCCAT ATGGCAAAATATGTGTGGATTGCTGAGTATTTTTACCAAGGTTTTAAGCGATGATGATCTGTTACAGACTGTACAGAGCACATCTGGATTAGCTATTATT CTTTTTATTAAGACTATGTTTCACCCGTCTGAAAAGATTCCTCATTTGATTAGCAGTGTGCTGCTTCGTTCAGTGGACTGCACCAGTGTCCCCGAGTGGT TTATGAGCAGCTGCAGGAGCCTCTGTTGTGGTGACATCTCTCAGTCAGCTGTCTTATTCCTCTGTCAGGGGACACTTGCCATGTTGGACTGGCAGAACGG AAGCATGGGTCGGAGTGGGGAGGCCCTGCTCTTGGATACTGCACATGTTTTGTTCACCTTGAGTTCACAGATTAAAGAGCCAACGCTGGAAATGTTTCTG TCTAGAATCTTAGCATCCTGGACTAATTCAGCCATACAAGTCCTTGAATCAAGTTCCCCGAGCCTAACGGACAGCCTGAATGGGAATTCAAGTATAGTTG GGAGACTTTTGGAATATGTCTATACCCATTGGGAACATCCATTGGATGCTCTGAGACACCAAACCAAAATCATGTTCAAAAACCTTCTCCAAATGCACCG GCTCACTGTGGAAGGTGCAGATTTCGTCCCTGATCCTTTCTTTGTGGAATTGACTGAGAGTCTTTTACGATTGGAATGGCATATTAAAGGAAAGTACACG TGCCTTGGTTGTTTGGTAGAGTGCATAGGAGTTGAACATATTTTGGCTATAGATAAAACTATTCCATCTCAAATCTTAGAGGTGATGGGAGACCAGTCAT TGGTACCTTATGCAAGTGACCTCTTGGAAACCATGTTTAGAAATCATAAGAGTCATTTGAAATCCCAGACTGCTGAGAGTTCTTGGATTGACCAGTGGCA TGAGACTTGGGTTTCTCCTCTCCTTTTTATATTGTGTGAAGGAAACTTGGATCAAAAATCTTACGTGATTGATTATTACTTGCCAAAATTATTAAGTTAC AGCCCTGAAAGCTTACAGTACATGGTAAAGATTCTTCAGACTTCTATTGATGCTAAAACTGGACAAGAGCAATCTTTCCCATCCTTAGGGTCTTGTAATA GCAGGGGGGCTCTGGGAGCTTTGATGGCATGTCTGCGAATAGCTAGAGCTCATGGACATCTTCAGTCTGCAACTGATACCTGGGAGAACCTCGTGTCTGA TGCAAGAATAAAGCAAGGCTTAATTCATCAGCATTGCCAAGTAAGGATAGATACATTAGGCTTGCTTTGTGAAAGTAATCGGAGCACAGAAATTGTTTCC ATGGAAGAAATGCAGTGGATTCAGTTCTTTATTACATACAATCTTAACAGCCAGTCTCCAGGAGTGCGGCAACAGATCTGTTCTCTTCTTAAAAAGTTGT TTTGTAGGATACAGGAAAGTTCTCAGGTACTTTATAAATTGGAGCAGAGTAAATCCAAACGTGAACCAGAGAATGAGTTAACCAAACAGCACCCTTCTGT TTCTTTACAGCAGTATAAGAATTTCATGTCATCCATTTGTAACAGTCTTTTTGAAGCATTGTTTCCTGGATCTTCCTACTCGACTAGATTTTCAGCTTTA ACCATTTTAGGTTCAATAGCTGAAGTTTTTCATGTCCCAGAAGGCAGAATTTATACAGTATATCAGCTGAGTCATGATATTGATGTTGGTCGTTTCCAAA CACTAATGGAATGTTTTACCAGCACTTTTGAAGACGTGAAAATTTTAGCATTTGATCTTCTGATGAAGTTATCAAAAACAGCTGTACATTTTCAGGATTC GGGGAAACTGCAAGGCTTATTTCAGGCAGCATTGGAGCTCAGCACAAGCACCAAACCATACGACTGTGTGACAGCTTCCTACCTGCTGAACTTCTTAATC TGGCAGGATGCTCTACCGTCATCCTTGTCTGCCTACTTAACTCAGCAAGTTGCATGTGATAATGGAGATAGGCCTGCTGCTGTGGTGGAAAGGAACACAT TAATGGTTATCAAATGCTTGATGGAAAATCTTGAGGAAGAAGTATCTCAGGCTGAAAATTCTCTGCTTCAGGCAGCAGCAGCATTTCCAATGTATGGGCG AGTCCACTGTATAACAGGAGCTTTGCAGAAGTTATCTCTAAACAGCCTGCAGTTGGTGAGCGAGTGGAGACCTGTGGTAGAGAAGCTCCTTTTGATGTCC TACAGGCTTTCCACTGTGGTGTCTCCAGTCATTCAGAGCTCATCCCCTGAAGGCCTCATCCCAATGGACACTGATTCAGAGTCAGCAAGCCGCTTACAGA TGATTCTGAATGAGATTCAGCCTCGAGATACTAATGATTATTTTAACCAAGCCAAAATATTGAAAGAACATGATAGCTTTGATATGAAGGACTTGAATGC TAGTGTGGTGAATATTGATACTTCTACAGAAATCAAAGGTAAAGAAGTAAAAACATGTGATGTAACTGCGCAGATGGTGCTGGTATGTTGTTGGAGAAGT ATGAAGGAAGTTGCTTTACTTTTAGGCATGTTGTGCCAGCTTCTGCCCATGCAGCCTGTGCCAGAATCTTCTGATGGATTATTGACGGTGGAGCAGGTAA AAGAAATAGGAGATTACTTTAAACAACACCTTTTGCAGTCCAGGCACAGAGGAGCATTTGAATTGGCTTATACTGGTTTTGTGAAACTCACTGAAGTACT AAACAGGTGCCCAAATGTGAGTCTGCAAAAGCTGCCAGAACAGTGGCTATGGAGTGTTTTAGAGGAAATTAAATGCAGTGATCCTTCATCTAAACTCTGT GCTACAAGGCGCAGTGCTGGAATTCCTTTCTACATACAGGCACTGTTGGCATCTGAACCAAAGAAAGGCAGAATGGATTTGTTGAAAATAACAATGAAAG AGTTAATCTCTTTGGCTGGGCCTACAGATGACATACAGAGTACAGTCCCCCAGGTTCATGCTTTAAATATCCTTAGAGCATTGTTCAGAGATACGCGCCT GGGAGAAAATATTATTCCTTATGTTGCTGATGGAGCTAAGGCTGCAATTCTGGGTTTTACATCACCGGTCTGGGCAGTGCGAAATTCATCCACACTTCTC TTTAGTGCCTTGATCACAAGAATTTTTGGAGTTAAAAGGGCAAAGGATGAACATTCCAAAACAAATAGAATGACAGGGAGAGAGTTTTTCTCTCGTTTCC CAGAACTCTATCCTTTTCTTCTCAAACAGTTGGAAACTGTAGCCAATACAGTAGACAGTGATATGGGAGAACCAAATCGTCATCCAAGCATGTTTCTCTT ACTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCATTATGAGGTGTGGTCAC TCACCTGTCTACCACTCCCGTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTAATACCATTCGAACTCTGTTGTCCACAC TCCCCAGCTGCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGTTTTTCATTTGTTGCAAGCCTACTCAGACTCCAAACACGG AACGAATTCAGACTTCCAGCACGAGCTGACTGACATCACTGTTTGTACCAAAGCCAAACTCTGGCTGGCCAAGAGGCAAAATCCATGTTTGGTGACCAGA GCTGTATATATTGATATTCTCTTCCTATTGACTTGCTGCCTCAACAGATCTGCAAAGGACAACCAGCCAGTTCTGGAGAGTCTTGGCTTCTGGGAGGAAG TCAGAGGGATTATCTCAGGATCAGAGCTGATAACGGGATTCCCTTGGGCCTTCAAGGTGCCAGGCCTGCCCCAGTACCTCCAGAGCCTCACCAGACTAGC CATTGCTGCAGTGTGGGCCGCGGCAGCCAAGAGTGGAGAGCGGGAGACGAATGTCCCCATCTCTTTCTCTCAGCTGTTAGAATCTGCCTTCCCTGAAGTG CGCTCACTAACACTGGAAGCCCTCTTGGAAAAGTTCTTAGCAGCAGCCTCTGGACTTGGAGAGAAGGGCGTGCCACCCTTGCTGTGCAACATGGGAGAGA AGTTCTTATTGTTGGCCATGAAGGAAAATCACCCAGAATGCTTCTGCAAGATACTGAAAATTCTCCACTGCATGGACCCTGGTGAGTGGCTTCCCCAGAC GGAGCACTGTGTCCATCTGACCCCAAAGGAGTTCTTGATCTGGACGATGGATATTGCTTCCAATGAAAGATCTGAAATTCAGAGTGTAGCTCTGAGACTT GCTTCCAAAGTCATTTCCCACCACATGCAGACATGTGTGGAGAACAGGGAATTGATAGCTGCTGAGCTGAAGCAGTGGGTTCAGCTGGTCATCTTGTCAT GTGAAGACCATCTTCCTACAGAGTCTAGGCTGGCCGTCGTTGAAGTCCTCACCAGTACTACACCACTTTTCCTCACCAACCCCCATCCTATTCTTGAGTT GCAGGATACACTTGCTCTCTGGAAGTGTGTCCTTACCCTTCTGCAGAGTGAGGAGCAAGCTGTTAGAGATGCAGCCACGGAAACCGTGACAACTGCCATG TCACAAGAAAATACCTGCCAGTCAACAGAGTTTGCCTTCTGCCAGGTGGATGCCTCCATCGCTCTGGCCCTGGCCCTGGCCGTCCTGTGTGATCTGCTCC AGCAGTGGGACCAGTTGGCCCCTGGACTGCCCATCCTGCTGGGATGGCTGTTGGGAGAGAGTGATGACCTCGTGGCCTGTGTGGAGAGCATGCATCAGGT GGAAGAAGACTACCTGTTTGAAAAAGCAGAAGTCAACTTTTGGGCCGAGACCCTGATCTTTGTGAAATACCTCTGCAAGCACCTCTTCTGTCTCCTCTCA AAGTCCGGCTGGCGTCCCCCAAGCCCTGAGATGCTCTGTCACCTTCAAAGGATGGTGTCAGAGCAGTGCCACCTCCTGTCTCAGTTCTTCAGAGAGCTTC CACCAGCTGCTGAGTTTGTGAAGACAGTGGAGTTCACAAGACTACGCATTCAAGAGGAAAGGACTTTGGCTTGCTTGAGGCTGCTGGCCTTTTTGGAAGG AAAGGAAGGGGAAGACACCCTAGTTCTCAGTGTTTGGGACTCTTATGCAGAATCGAGGCAGTTAACTCTTCCAAGAACAGAAGCGGCATGTTGAAGAAAA TCTGGGGGATTGGGATGGGGGTATGTGTGGATTTTTCCTCCACTAAATCTGCAGGAAACATGTTGAACATAAATTCAAAAATTTTATCCC

refseq_THADA.F2 (forward primer)
refseq_THADA.R2 (reverse primer)
Multiple exon skipping

Frame 0

SRPWTALRASETP*KETCFRDWTRRLRLFSDAD VHE*LLLILFKMGVKKKKEMQVAALTICHQDLET LKSFADVEGKNLASLLLHCVQLTDGVSQIHYIK QIVPLLEKADKNGMCDPTIQSCLDILAGIYLSL SLKNPLKKVLASSLNSLPDFFLPEAMHRFTSRLQ EELNTTDLYSYRKVTDNISSCMENFNLGRASVN NLLKNVLHFLQKSLIEILEENRKCAGNHIIQTQ LMNDLLVGIRVSMMLVQKVQDFQGNLWKTSDSPI WQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAII LFIKTMFHPSEKIPHLISSVLLRSVDCTSVPEW FMSSCRSLCCGDISQSAVLFLCQGTLAMLDWQNG SMGRSGEALLLDTAHVLFTLSSQIKEPTLEMFL SRILASWTNSAIQVLESSSPSLTDSLNGNSSIV GRLLEYVYTHWEHPLDALRHQTKIMFKNLLQMHR LTVEGADFVPDPFFVELTESLLRLEWHIKGKYT CLGCLVECIGVEHILAIDKTIPSQILEVMGDQS LVPYASDLLETMFRNHKSHLKSQTAESSWIDQWH ETWVSPLLFILCEGNLDQKSYVIDYYLPKLLSY SPESLQYMVKILQTSIDAKTGQEQSFPSLGSCN SRGALGALMACLRIARAHGHLQSATDTWENLVSD ARIKQGLIHQHCQVRIDTLGLLCESNRSTEIVS MEEMQWIQFFITYNLNSQSPGVRQQICSLLKKL FCRIQESSQVLYKLEQSKSKREPENELTKQHPSV SLQQYKNFMSSICNSLFEALFPGSSYSTRFSAL TILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQ TLMECFTSTFEDVKILAFDLLMKLSKTAVHFQDS GKLQGLFQAALELSTSTKPYDCVTASYLLNFLI WQDALPSSLSAYLTQQVACDNGDRPAAVVERNT LMVIKCLMENLEEEVSQAENSLLQAAAAFPMYGR VHCITGALQKLSLNSLQLVSEWRPVVEKLLLMS YRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQ MILNEIQPRDTNDYFNQAKILKEHDSFDMKDLNA SVVNIDTSTEIKGKEVKTCDVTAQMVLVCCWRS MKEVALLLGMLCQLLPMQPVPESSDGLLTVEQV KEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVL NRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLC ATRRSAGIPFYIQALLASEPKKGRMDLLKITMK ELISLAGPTDDIQSTVPQVHALNILRALFRDTRL GENIIPYVADGAKAAILGFTSPVWAVRNSSTLL FSALITRIFGVKRAKDEHSKTNRMTGREFFSRF PELYPFLLKQLETVANTVDSDMGEPNRHPSMFLL LLVLERLYASPMDGTSSALSMGPFVPFIMRCGH SPVYHSREMAARALVPFVMIDHIPNTIRTLLST LPSCTDQCFRQNHIHGTLLQVFHLLQAYSDSKHG TNSDFQHELTDITVCTKAKLWLAKRQNPCLVTR AVYIDILFLLTCCLNRSAKDNQPVLESLGFWEE VRGIISGSELITGFPWAFKVPGLPQYLQSLTRLA IAAVWAAAAKSGERETNVPISFSQLLESAFPEV RSLTLEALLEKFLAAASGLGEKGVPPLLCNMGE KFLLLAMKENHPECFCKILKILHCMDPGEWLPQT EHCVHLTPKEFLIWTMDIASNERSEIQSVALRL ASKVISHHMQTCVENRELIAAELKQWVQLVILS CEDHLPTESRLAVVEVLTSTTPLFLTNPHPILEL QDTLALWKCVLTLLQSEEQAVRDAATETVTTAM SQENTCQSTEFAFCQVDASIALALALAVLCDLL QQWDQLAPGLPILLGWLLGESDDLVACVESMHQV EEDYLFEKAEVNFWAETLIFVKYLCKHLFCLLS KSGWRPPSPEMLCHLQRMVSEQCHLLSQFFREL PPAAEFVKTVEFTRLRIQEERTLACLRLLAFLEG KEGEDTLVLSVWDSYAESRQLTLPRTEAAC*RK SGGLGWGYVWIFPPLNLQETC*T*IQKFYP

Frame 1

VDRGPRCEPRRRRRRRPASGTGPGACDSSQTPT CTSDYY*FYLKWV*RRRKKCKLLR*PFAIRTLK L*NLLLMWKGKI*LLCCYIVCNSRMECHKSIILN RLCLCWRKQIKMACVIPLFKVVWIS*QAFIFL* V*RIP*RKYWQAH*IACLIFFYLRLCTVLLLVF RKN*ILLTYTLTGKLLTIFLPVWRTLTWVEQVLI ICLKMCFIFCRRV*LKSWKKIENVLEIILFKHS **MTYW*ALEFQ*C*YRKYKISREIFGRLPILP YGKICVDC*VFLPRF*AMMICYRLYRAHLD*LLF FLLRLCFTRLKRFLI*LAVCCFVQWTAPVSPSG L*AAAGASVVVTSLSQLSYSSVRGHLPCWTGRT EAWVGVGRPCSWILHMFCSP*VHRLKSQRWKCFC LES*HPGLIQPYKSLNQVPRA*RTA*MGIQV*L GDFWNMSIPIGNIHWML*DTKPKSCSKTFSKCT GSLWKVQISSLILSLWN*LRVFYDWNGILKESTR ALVVW*SA*ELNIFWL*IKLFHLKS*R*WETSH WYLMQVTSWKPCLEIIRVI*NPRLLRVLGLTSG MRLGFLLSFLYCVKETWIKNLT*LIITCQNY*VT ALKAYSTW*RFFRLLLMLKLDKSNLSHP*GLVI AGGLWEL*WHVCE*LELMDIFSLQLIPGRTSCL MQE*SKA*FISIAK*G*IH*ACFVKVIGAQKLFP WKKCSGFSSLLHTILTASLQECGNRSVLFLKSC FVGYRKVLRYFINWSRVNPNVNQRMS*PNSTLL FLYSSIRISCHPFVTVFLKHCFLDLPTRLDFQL* PF*VQ*LKFFMSQKAEFIQYIS*VMILMLVVSK H*WNVLPALLKT*KF*HLIF**SYQKQLYIFRI RGNCKAYFRQHWSSAQAPNHTTV*QLPTC*TS*S GRMLYRHPCLPT*LSKLHVIMEIGLLLWWKGTH *WLSNA*WKILRKKYLRLKILCFRQQQHFQCMG ESTV*QELCRSYL*TACSW*ASGDLW*RSSF*CP TGFPLWCLQSFRAHPLKASSQWTLIQSQQAAYR *F*MRFSLEILMIILTKPKY*KNMIALI*RT*M LVW*ILILLQKSKVKK*KHVM*LRRWCWYVVGEV *RKLLYF*ACCASFCPCSLCQNLLMDY*RWSR* KK*EITLNNTFCSPGTEEHLNWLILVL*NSLKY *TGAQM*VCKSCQNSGYGVF*RKLNAVILHLNSV LQGAVLEFLSTYRHCWHLNQRKAEWIC*K*Q*K S*SLWLGLQMTYRVQSPRFML*ISLEHCSEIRA WEKILFLMLLMELRLQFWVLHHRSGQCEIHPHFS LVP*SQEFLELKGQRMNIPKQIE*QGESFSLVS QNSILFFSNSWKL*PIQ*TVIWENQIVIQACFS YFWCWRDSTLPRWMVLLLLSAWDLLFPSL*GVVT HLSTTPVKWQLVPWSHLL**ITFLIPFELCCPH SPAALTSVSGKTTFMGHFSRFFICCKPTQTPNT ERIQTSSTS*LTSLFVPKPNSGWPRGKIHVW*PE LYILIFSSY*LAASTDLQRTTSQFWRVLASGRK SEGLSQDQS**RDSLGPSRCQACPSTSRASPD* PLLQCGPRQPRVESGRRMSPSLSLSC*NLPSLKC AH*HWKPSWKSS*QQPLDLERRACHPCCATWER SSYCWP*RKITQNASARY*KFSTAWTLVSGFPR RSTVSI*PQRSS*SGRWILLPMKDLKFRV*L*DL LPKSFPTTCRHVWRTGN**LLS*SSGFSWSSCH VKTIFLQSLGWPSLKSSPVLHHFSSPTPILFLS CRIHLLSGSVSLPFCRVRSKLLEMQPRKP*QLPC HKKIPASQQSLPSARWMPPSLWPWPWPSCVICS SSGTSWPLDCPSCWDGCWERVMTSWPVWRACIR WKKTTCLKKQKSTFGPRP*SL*NTSASTSSVSSQ SPAGVPQALRCSVTFKGWCQSSATSCLSSSESF HQLLSL*RQWSSQDYAFKRKGLWLA*GCWPFWK ERKGKTP*FSVFGTLMQNRGS*LFQEQKRHVEEN LGDWDGGMCGFFLH*ICRKHVEHKFKNFI

Frame 2

STVDRAASLGDAVEGDLLPGLDQAPATLLRRRR ARVTTINSI*NGCKEEERNASCCADHLPSGP*N FEIFC*CGREKSSFFAVTLCATHGWSVTNPLY* TDCASAGESR*KWHV*SHYSKLFGYLSRHLSFFE SKESLEESIGKLTK*PA*FFST*GYAPFYFSSS GRIEYY*LILLQESY*QYFFLYGEL*LG*SKC* *SA*KCASFSAEEFN*NPGRK*KMCWKSYYSNTV DE*LTGRH*SFNDVSTESTRFPGKSLEDFRFSH MAKYVWIAEYFYQGFKR**SVTDCTEHIWISYY SFY*DYVSPV*KDSSFD*QCAASFSGLHQCPRVV YEQLQEPLLW*HLSVSCLIPLSGDTCHVGLAER KHGSEWGGPALGYCTCFVHLEFTD*RANAGNVS V*NLSILD*FSHTSP*IKFPEPNGQPEWEFKYSW ETFGICLYPLGTSIGCSETPNQNHVQKPSPNAP AHCGRCRFRP*SFLCGID*ESFTIGMAY*RKVH VPWLFGRVHRS*TYFGYR*NYSISNLRGDGRPVI GTLCK*PLGNHV*KS*ESFEIPDC*EFLD*PVA *DLGFSSPFYIV*RKLGSKILRD*LLLAKIIKL QP*KLTVHGKDSSDFY*C*NWTRAIFPILRVL** QGGSGSFDGMSANS*SSWTSSVCN*YLGEPRV* CKNKARLNSSALPSKDRYIRLAL*K*SEHRNCF HGRNAVDSVLYYIQS*QPVSRSAATDLFSS*KVV L*DTGKFSGTL*IGAE*IQT*TRE*VNQTAPFC FFTAV*EFHVIHL*QSF*SIVSWIFLLD*IFSF NHFRFNS*SFSCPRRQNLYSISAES*Y*CWSFPN TNGMFYQHF*RRENFSI*SSDEVIKNSCTFSGF GETARLISGSIGAQHKHQTIRLCDSFLPAELLN LAGCSTVILVCLLNSASCM**WR*ACCCGGKEHI NGYQMLDGKS*GRSISG*KFSASGSSSISNVWA SPLYNRSFAEVISKQPAVGERVETCGREAPFDV LQAFHCGVSSHSELIP*RPHPNGH*FRVSKPLTD DSE*DSASRY**LF*PSQNIERT**L*YEGLEC *CGEY*YFYRNQR*RSKNM*CNCADGAGMLLEK YEGSCFTFRHVVPASAHAACARIF*WIIDGGAGK RNRRLL*TTPFAVQAQRSI*IGLYWFCETH*ST KQVPKCESAKAARTVAMECFRGN*MQ*SFI*TL CYKAQCWNSFLHTGTVGI*TKERQNGFVENNNER VNLFGWAYR*HTEYSPPGSCFKYP*SIVQRYAP GRKYYSLCC*WS*GCNSGFYITGLGSAKFIHTS L*CLDHKNFWS*KGKG*TFQNK*NDRERVFLSFP RTLSFSSQTVGNCSQYSRQ*YGRTKSSSKHVSL TFGVGETLRFPDGWYFFCSQHGTFCSLHYEVWS LTCLPLP*NGSSCLGPICYDRSHS*YHSNSVVHT PQLH*PVFPAKPHSWDTSPGFSFVASLLRLQTR NEFRLPARAD*HHCLYQSQTLAGQEAKSMFGDQ SCIY*YSLPIDLLPQQICKGQPASSGESWLLGGS QRDYLRIRADNGIPLGLQGARPAPVPPEPHQTS HCCSVGRGSQEWRAGDECPHLFLSAVRICLP*S ALTNTGSPLGKVLSSSLWTWREGRATLAVQHGRE VLIVGHEGKSPRMLLQDTENSPLHGPW*VASPD GALCPSDPKGVLDLDDGYCFQ*KI*NSECSSET CFQSHFPPHADMCGEQGIDSC*AEAVGSAGHLVM *RPSSYRV*AGRR*SPHQYYTTFPHQPPSYS*V AGYTCSLEVCPYPSAE*GASC*RCSHGNRDNCH VTRKYLPVNRVCLLPGGCLHRSGPGPGRPV*SAP AVGPVGPWTAHPAGMAVGRE**PRGLCGEHASG GRRLPV*KSRSQLLGRDPDLCEIPLQAPLLSPL KVRLASPKP*DALSPSKDGVRAVPPPVSVLQRAS TSC*VCEDSGVHKTTHSRGKDFGLLEAAGLFGR KGRGRHPSSQCLGLLCRIEAVNSSKNRSGMLKK IWGIGMGVCVDFSSTKSAGNMLNINSKILS