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Sequences

Sequence NM_001040273

AATCGGGCTCGATGAGGAAGACGTGAGTCAGAGCTTGCGCCTCTCGCTTCCAGCTGTGGGTGGCGCTAGGCAGCTTCAGCCGGACCGGGTAGGGGTCCTC
GCTCGCTAGCTTGCTGTTTCTCGGAGAAGCTCCCGAGTGTCCGGCCTAGAGGCCATGAGAAGGCAGTGGGGGTCTGCCATGAGGGCGGCCGAGCAGGCGG
GCTGCATGGTGAGCGCCTCCCGGGCCGGACAGCCCGAGGCGGGCCCGTGGAGCTGCAGCGGGGTAATCCTGAGCCGTAGCCCGGGCCTGGTGCTTTGCCA
CGGGGGCATCTTCGTCCCCTTCCTGCGAGCTGGCAGCGAAGTCCTGACCGCGGCCGGCGCCGTCTTCCTGCCTGGCGACAGTTGCAGGGACGACCTGCGC
CTGCACGTGCAGTGGGCCCCAACGGCCGCGGGTCCCGGGGGCGGCGCGGAGCGGGGCCGCCCAGGGCTGTGCACGCCCCAGTGCGCGAGCCTCGAGCCCG
GCCCACCTGCCCCGTCCCGCGGGCGTCCCCTGCAGCCCCGGCTTCCTGCTGAGCTGCTGCTGCTGCTGAGCTGCCCGGCCTTCTGGGCCCACTTCGCGCG
CCTCTTCGGGGACGAGGCAGCGGAACAGTGGCGCTTCTCGAGCGCGGCGCGGGATGACGAAGTGTCGGAGGACGAGGAGGCGGATCAACTGAGAGCGCTG
GGCTGGTTTGCGCTGCTGGGCGTGCGGCTAGGCCAGGAGGAGGTGGAGGAGGAGCGCGGGCCAGCCATGGCGGTGTCGCCTCTCGGGGCCGTGCCCAAGG
GTGCGCCATTGCTGGTCTGCGGCTCCCCTTTCGGCGCCTTCTGCCCCGACATCTTTCTCAACACGCTGAGCTGCGGGGTGCTCAGCAACGTGGCCGGCCC
ACTGCTGCTTACCGACGCACGCTGCCTGCCCGGCACCGAGGGCGGCGGCGTGTTCACCGCGCGGCCCGCGGGGGCGCTGGTGGCGCTGGTGGTGGCGCCG
CTCTGTTGGAAGGCCGGCGAATGGGTGGGCTTCACGCTGCTCTGCGCCGCCGCCCCCCTTTTCCGCGCCGCCCGCGACGCGCTTCACCGCCTGCCGCACA
GCACCGCTGCCCTGGCCGCCCTTCTGCCGCCAGAGGTGGGCGTCCCGTGGGGTCTGCCCCTCCGAGACTCCGGGCCCCTGTGGGCAGCCGCGGCAGTGTT
GGTGGAGTGCGGCACCGTATGGGGCTCCGGAGTGGCTGTGGCACCCCGCCTTGTAGTGACCTGTCGGCACGTGTCCCCTCGGGAAGCAGCCAGGGTCCTG
GTGCGCTCCACCACCCCCAAGCATAATCACCAGCAACACCCGGGACAATAATACGGGGGCCACCTACCCCCACCTGAACTTCAGCATTCCCATCACGGTG
CTCCAGCCGGCCCTGCAGCAGTACAGCCAGACCCAAGACCTAGGTGGCCTCCGTGAGCTGGACCGCGCTGCTGAGCCAGTCAGGGTGGTGTGGCGGTTGC
AGCGGCCCCTGGCAGAGGCCCCGCGGAGCAAGCTCTGAGGCTGTGTTACCACCTTTGGAAAGAAGAGTGACCTTTTTCTGCTGTAGGAAGTGATGTTGAG
GTGACGGTGGCCTCAGGATTCAGGGCCCAGCCCCTGCAGGGGCCCAGGCTGCCTCTCATCTCCACCCACTGACTGCAGACTGGGCTTTGGGCTCTGGGGC
AAACTTCTCTTCAGCCCCATGGATCCTTAACCTGGCAGCCCGTTTTGGGGTGCTTTCTTGAGCCCCCAGTTCTCTGTCCCCTAGCACTAGACTCAGCTGT
ATTGTTTTTCCTTCTGGGGAGCCCACTCCAACTGCACAGAAGTTCTGGGCCTGACAGGTAGATTCCAGCTGGAAGGCAGGCCCGTGCCTGGTTTTGCGTC
TGTTCCCCTGAGGGCCATCGTCATCCTGGAGCTTCAATGGGGCCTTGGCTCCTGTCTGCCTCTCAGTCAGAGTCAGGGCTGACAAAGGACTCAGCTTCCT
TAGCATCTCAGCAGAAACCTTGCTCTGAAGACCAGAGACAGAAGGGACAGAAACAGGAGTGCCTCCTGCTGTGCCAGGCCCATGGGCAGTGCAGGCAGAT
CCCTGAAGGTCAGCACTCCTGGGTCTTCATATGCCAACAGGGGCGCTCTTGACACTGTGCCTTCATTTTCCAGCCCACAGCCTGGGTCTCAGGGATCTTG
AGGGGTAGAACATGTCTGGTTGGGGCTTGGGAATAAACATGATCTATTGAAAAACCTCTGTATTTATATATCAAATTGTTTCTTTTTTTCAGGAGTTGAA
CTGGGAATAGGCAAGTACCAGGCAAAGAAACACACCCTTTCCTTTTTTTTTTTTTTTTTTCTTTAGAGCTGTGGTCTTGCTCTCTCACCCAGGCTGGAGT
GCAGTGTTGCGATCACAGCTCACTGCAGCCTCAAACTCCTGGGCTCCAGGAGACCTCCTGCCTCAGCCTCCTGAATAGCTGGGACTACAGTCGCGCACCA
CCACGCCTGGCTAATTTTTTATTTTTGTAGAAATGGGGTATTGCTTTGTTGCCCGTGCTGGCTTCAGCCTTCTGGTTTCAAGCAGTCCTCCTGCCTCAGC
TTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGTGCCCAACCCAGAAATACACCCTTTCTGTGCTGTTTTCTCAGCAGGGTGTGAGCTCACGGGATA
CGGTCCTGCCAGACTGGCCCTCATAGCTGGTCATGTGCCAGTCAGAGCTGGGTGGGGCTTGCAGGTCCCGGAAGGTGGTGGTCTTGACCTGGCAGCAGAT
GCTTAAAGAATGCCTAAGGTGGGTGGCAGTTGGGGAGTTCAAGGGTGAATGAGGCCAGGGCAGCCCCCAGGAGCTGAGGCCAACTCTTTGAGTCAGGACT
GTGCCGTGTGCCCAGGGCCTTGCATGTGTGGGCCCTCGAGTGATTTCTACTGGCAGGCTGAAAGCCCTGTGAGGGGCGGCTGTGGGCGGAGGCCACGCAG
GAAGAGTGCTTAGGAGTAACTTGTTTCTAACACCTGTGTGCTGAGTGCCAATGCTGGGTGTGGTGTTATGATATATATTGGTTTTCATCCAGCATTCCTG
ACTCGTAACTCTCATAGTCCTTGTTCCAGTCTTTGTTAGAATACTGGGTATGTTAGGGCTTGGGACAGGCCTCTGACCTCTGGGTATCCTTTCACTAATG
TTCGCCCACCTTTTTCACAGTGGGTCCTAAAGACCTTCCCATGAGAGGGTCTCAATCCTAGGGGAAGGAATGTTGATGTCATGAACCTTCCATAAAAACC
CAAGAGGACAGGGTTCAGAGAGCTTCTGGATAGCTGAACACCTGGCACTTCCTGGAGTGTGGCGTGCCCAGGGAGGGCACGGAAGCTCTGCACTCCTTCC
CCTTCCCTCATTCCTTGCTCTATGTGCATCTCTTCATCTGTATCCTTTGCGATATCCTTTATAATAAACCGGTAAACATAAGTAA
  • refseq_TYSND1.F1 (forward primer)
  • refseq_TYSND1.R1 (reverse primer)
  • Multiple exon skipping

Frame 0

NRAR*GRRESELAPLASSCGWR*AASAGPGRGP
RSLACCFSEKLPSVRPRGHEKAVGVCHEGGRAGG
LHGERLPGRTARGGPVELQRGNPEP*PGPGALP
RGHLRPLPASWQRSPDRGRRRLPAWRQLQGRPA
PARAVGPNGRGSRGRRGAGPPRAVHAPVREPRAR
PTCPVPRASPAAPASC*AAAAAELPGLLGPLRA
PLRGRGSGTVALLERGAG*RSVGGRGGGSTESA
GLVCAAGRAARPGGGGGGARASHGGVASRGRAQG
CAIAGLRLPFRRLLPRHLSQHAELRGAQQRGRP
TAAYRRTLPARHRGRRRVHRAARGGAGGAGGGA
ALLEGRRMGGLHAALRRRPPFPRRPRRASPPAAQ
HRCPGRPSAARGGRPVGSAPPRLRAPVGSRGSV
GGVRHRMGLRSGCGTPPCSDLSARVPSGSSQGP
GALHHPQA*SPATPGTIIRGPPTPT*TSAFPSRC
SSRPCSSTARPKT*VASVSWTALLSQSGWCGGC
SGPWQRPRGASSEAVLPPLERRVTFFCCRK*C*
GDGGLRIQGPAPAGAQAASHLHPLTADWALGSGA
NFSSAPWILNLAARFGVLS*APSSLSPSTRLSC
IVFPSGEPTPTAQKFWA*QVDSSWKAGPCLVLR
LFP*GPSSSWSFNGALAPVCLSVRVRADKGLSFL
SISAETLL*RPETEGTETGVPPAVPGPWAVQAD
P*RSALLGLHMPTGALLTLCLHFPAHSLGLRDL
EG*NMSGWGLGINMIY*KTSVFIYQIVSFFQELN
WE*ASTRQRNTPFPFFFFFFFRAVVLLSHPGWS
AVLRSQLTAASNSWAPGDLLPQPPE*LGLQSRT
TTPG*FFIFVEMGYCFVARAGFSLLVSSSPPASA
SQSAGITGVSHCAQPRNTPFLCCFLSRV*AHGI
RSCQTGPHSWSCASQSWVGLAGPGRWWS*PGSR
CLKNA*GGWQLGSSRVNEARAAPRS*GQLFESGL
CRVPRALHVWALE*FLLAG*KPCEGRLWAEATQ
EECLGVTCF*HLCAECQCWVWCYDIYWFSSSIP
DS*LS*SLFQSLLEYWVC*GLGQASDLWVSFH*C
SPTFFTVGPKDLPMRGSQS*GKEC*CHEPSIKT
QEDRVQRASG*LNTWHFLECGVPREGTEALHSF
PFPHSLLYVHLFICILCDILYNKPVNIS

Frame 1

IGLDEEDVSQSLRLSLPAVGGARQLQPDRVGVL
AR*LAVSRRSSRVSGLEAMRRQWGSAMRAAEQA
GCMVSASRAGQPEAGPWSCSGVILSRSPGLVLCH
GGIFVPFLRAGSEVLTAAGAVFLPGDSCRDDLR
LHVQWAPTAAGPGGGAERGRPGLCTPQCASLEP
GPPAPSRGRPLQPRLPAELLLLLSCPAFWAHFAR
LFGDEAAEQWRFSSAARDDEVSEDEEADQLRAL
GWFALLGVRLGQEEVEEERGPAMAVSPLGAVPK
GAPLLVCGSPFGAFCPDIFLNTLSCGVLSNVAGP
LLLTDARCLPGTEGGGVFTARPAGALVALVVAP
LCWKAGEWVGFTLLCAAAPLFRAARDALHRLPH
STAALAALLPPEVGVPWGLPLRDSGPLWAAAAVL
VECGTVWGSGVAVAPRLVVTCRHVSPREAARVL
VRSTTPKHNHQQHPGQ*YGGHLPPPELQHSHHG
APAGPAAVQPDPRPRWPP*AGPRC*ASQGGVAVA
AAPGRGPAEQALRLCYHLWKEE*PFSAVGSDVE
VTVASGFRAQPLQGPRLPLISTH*LQTGLWALG
QTSLQPHGSLTWQPVLGCFLEPPVLCPLALDSAV
LFFLLGSPLQLHRSSGPDR*IPAGRQARAWFCV
CSPEGHRHPGASMGPWLLSASQSESGLTKDSAS
LASQQKPCSEDQRQKGQKQECLLLCQAHGQCRQI
PEGQHSWVFICQQGRS*HCAFIFQPTAWVSGIL
RGRTCLVGAWE*T*SIEKPLYLYIKLFLFFRS*
TGNRQVPGKETHPFLFFFFFSLELWSCSLTQAGV
QCCDHSSLQPQTPGLQETSCLSLLNSWDYSRAP
PRLANFLFL*KWGIALLPVLASAFWFQAVLLPQ
LPKVLGLQV*ATVPNPEIHPFCAVFSAGCELTGY
GPARLALIAGHVPVRAGWGLQVPEGGGLDLAAD
A*RMPKVGGSWGVQG*MRPGQPPGAEANSLSQD
CAVCPGPCMCGPSSDFYWQAESPVRGGCGRRPRR
KSA*E*LVSNTCVLSANAGCGVMIYIGFHPAFL
TRNSHSPCSSLC*NTGYVRAWDRPLTSGYPFTN
VRPPFSQWVLKTFP*EGLNPRGRNVDVMNLP*KP
KRTGFRELLDS*TPGTSWSVACPGRARKLCTPS
PSLIPCSMCISSSVSFAISFIINR*T*V

Frame 2

SGSMRKT*VRACASRFQLWVALGSFSRTG*GSS
LASLLFLGEAPECPA*RP*EGSGGLP*GRPSRR
AAW*APPGPDSPRRARGAAAG*S*AVARAWCFA
TGASSSPSCELAAKS*PRPAPSSCLATVAGTTCA
CTCSGPQRPRVPGAARSGAAQGCARPSARASSP
AHLPRPAGVPCSPGFLLSCCCC*AARPSGPTSR
ASSGTRQRNSGASRARRGMTKCRRTRRRIN*ERW
AGLRCWACG*ARRRWRRSAGQPWRCRLSGPCPR
VRHCWSAAPLSAPSAPTSFSTR*AAGCSATWPA
HCCLPTHAACPAPRAAACSPRGPRGRWWRWWWRR
SVGRPANGWASRCSAPPPPFSAPPATRFTACRT
APLPWPPFCRQRWASRGVCPSETPGPCGQPRQC
WWSAAPYGAPEWLWHPAL**PVGTCPLGKQPGSW
CAPPPPSIITSNTRDNNTGATYPHLNFSIPITV
LQPALQQYSQTQDLGGLRELDRAAEPVRVVWRL
QRPLAEAPRSKL*GCVTTFGKKSDLFLL*EVMLR
*RWPQDSGPSPCRGPGCLSSPPTDCRLGFGLWG
KLLFSPMDP*PGSPFWGAFLSPQFSVP*H*TQL
YCFSFWGAHSNCTEVLGLTGRFQLEGRPVPGFAS
VPLRAIVILELQWGLGSCLPLSQSQG*QRTQLP
*HLSRNLALKTRDRRDRNRSASCCARPMGSAGR
SLKVSTPGSSYANRGALDTVPSFSSPQPGSQGS*
GVEHVWLGLGNKHDLLKNLCIYISNCFFFSGVE
LGIGKYQAKKHTLSFFFFFFL*SCGLALSPRLE
CSVAITAHCSLKLLGSRRPPASAS*IAGTTVAHH
HAWLIFYFCRNGVLLCCPCWLQPSGFKQSSCLS
FPKCWDYRCEPLCPTQKYTLSVLFSQQGVSSRD
TVLPDWPS*LVMCQSELGGACRSRKVVVLTWQQM
LKECLRWVAVGEFKGE*GQGSPQELRPTL*VRT
VPCAQGLACVGPRVISTGRLKAL*GAAVGGGHA
GRVLRSNLFLTPVC*VPMLGVVL*YILVFIQHS*
LVTLIVLVPVFVRILGMLGLGTGL*PLGILSLM
FAHLFHSGS*RPSHERVSILGEGMLMS*TFHKN
PRGQGSESFWIAEHLALPGVWRAQGGHGSSALLP
LPSFLALCASLHLYPLRYPL**TGKHK*

Sequence NM_173555

AATCGGGCTCGATGAGGAAGACGTGAGTCAGAGCTTGCGCCTCTCGCTTCCAGCTGTGGGTGGCGCTAGGCAGCTTCAGCCGGACCGGGTAGGGGTCCTC
GCTCGCTAGCTTGCTGTTTCTCGGAGAAGCTCCCGAGTGTCCGGCCTAGAGGCCATGAGAAGGCAGTGGGGGTCTGCCATGAGGGCGGCCGAGCAGGCGG
GCTGCATGGTGAGCGCCTCCCGGGCCGGACAGCCCGAGGCGGGCCCGTGGAGCTGCAGCGGGGTAATCCTGAGCCGTAGCCCGGGCCTGGTGCTTTGCCA
CGGGGGCATCTTCGTCCCCTTCCTGCGAGCTGGCAGCGAAGTCCTGACCGCGGCCGGCGCCGTCTTCCTGCCTGGCGACAGTTGCAGGGACGACCTGCGC
CTGCACGTGCAGTGGGCCCCAACGGCCGCGGGTCCCGGGGGCGGCGCGGAGCGGGGCCGCCCAGGGCTGTGCACGCCCCAGTGCGCGAGCCTCGAGCCCG
GCCCACCTGCCCCGTCCCGCGGGCGTCCCCTGCAGCCCCGGCTTCCTGCTGAGCTGCTGCTGCTGCTGAGCTGCCCGGCCTTCTGGGCCCACTTCGCGCG
CCTCTTCGGGGACGAGGCAGCGGAACAGTGGCGCTTCTCGAGCGCGGCGCGGGATGACGAAGTGTCGGAGGACGAGGAGGCGGATCAACTGAGAGCGCTG
GGCTGGTTTGCGCTGCTGGGCGTGCGGCTAGGCCAGGAGGAGGTGGAGGAGGAGCGCGGGCCAGCCATGGCGGTGTCGCCTCTCGGGGCCGTGCCCAAGG
GTGCGCCATTGCTGGTCTGCGGCTCCCCTTTCGGCGCCTTCTGCCCCGACATCTTTCTCAACACGCTGAGCTGCGGGGTGCTCAGCAACGTGGCCGGCCC
ACTGCTGCTTACCGACGCACGCTGCCTGCCCGGCACCGAGGGCGGCGGCGTGTTCACCGCGCGGCCCGCGGGGGCGCTGGTGGCGCTGGTGGTGGCGCCG
CTCTGTTGGAAGGCCGGCGAATGGGTGGGCTTCACGCTGCTCTGCGCCGCCGCCCCCCTTTTCCGCGCCGCCCGCGACGCGCTTCACCGCCTGCCGCACA
GCACCGCTGCCCTGGCCGCCCTTCTGCCGCCAGAGGTGGGCGTCCCGTGGGGTCTGCCCCTCCGAGACTCCGGGCCCCTGTGGGCAGCCGCGGCAGTGTT
GGTGGAGTGCGGCACCGTATGGGGCTCCGGAGTGGCTGTGGCACCCCGCCTTGTAGTGACCTGTCGGCACGTGTCCCCTCGGGAAGCAGCCAGGGTCCTG
GTGCGCTCCACCACCCCCAAGAGTGTGGCCATCTGGGGCCGTGTGGTATTTGCCACTCAGGAGACATGTCCCTATGACATAGCAGTGGTGAGCCTGGAGG
AGGACCTGGATGATGTCCCCATCCCTGTGCCCGCTGAGCACTTCCATGAAGGCGAGGCTGTGAGTGTGGTGGGCTTTGGCGTCTTTGGCCAGTCTTGCGG
GCCCTCGGTGACCTCAGGCATCCTTTCGGCTGTGGTGCAGGTGAATGGCACGCCCGTAATGCTGCAGACCACGTGTGCTGTGCACAGCGGCTCCAGTGGG
GGACCCCTCTTCTCCAACCACTCAGGAAACCTCCTTG
GCATAATCACCAGCAACACCCGGGACAATAATACGGGGGCCACCTACCCCCACCTGAACTTCA
GCATTCCCATCACGGTGCTCCAGCCGGCCCTGCAGCAGTACAGCCAGACCCAAGACCTAGGTGGCCTCCGTGAGCTGGACCGCGCTGCTGAGCCAGTCAG
GGTGGTGTGGCGGTTGCAGCGGCCCCTGGCAGAGGCCCCGCGGAGCAAGCTCTGAGGCTGTGTTACCACCTTTGGAAAGAAGAGTGACCTTTTTCTGCTG
TAGGAAGTGATGTTGAGGTGACGGTGGCCTCAGGATTCAGGGCCCAGCCCCTGCAGGGGCCCAGGCTGCCTCTCATCTCCACCCACTGACTGCAGACTGG
GCTTTGGGCTCTGGGGCAAACTTCTCTTCAGCCCCATGGATCCTTAACCTGGCAGCCCGTTTTGGGGTGCTTTCTTGAGCCCCCAGTTCTCTGTCCCCTA
GCACTAGACTCAGCTGTATTGTTTTTCCTTCTGGGGAGCCCACTCCAACTGCACAGAAGTTCTGGGCCTGACAGGTAGATTCCAGCTGGAAGGCAGGCCC
GTGCCTGGTTTTGCGTCTGTTCCCCTGAGGGCCATCGTCATCCTGGAGCTTCAATGGGGCCTTGGCTCCTGTCTGCCTCTCAGTCAGAGTCAGGGCTGAC
AAAGGACTCAGCTTCCTTAGCATCTCAGCAGAAACCTTGCTCTGAAGACCAGAGACAGAAGGGACAGAAACAGGAGTGCCTCCTGCTGTGCCAGGCCCAT
GGGCAGTGCAGGCAGATCCCTGAAGGTCAGCACTCCTGGGTCTTCATATGCCAACAGGGGCGCTCTTGACACTGTGCCTTCATTTTCCAGCCCACAGCCT
GGGTCTCAGGGATCTTGAGGGGTAGAACATGTCTGGTTGGGGCTTGGGAATAAACATGATCTATTGAAAAACCTCTGTATTTATATATCAAATTGTTTCT
TTTTTTCAGGAGTTGAACTGGGAATAGGCAAGTACCAGGCAAAGAAACACACCCTTTCCTTTTTTTTTTTTTTTTTTCTTTAGAGCTGTGGTCTTGCTCT
CTCACCCAGGCTGGAGTGCAGTGTTGCGATCACAGCTCACTGCAGCCTCAAACTCCTGGGCTCCAGGAGACCTCCTGCCTCAGCCTCCTGAATAGCTGGG
ACTACAGTCGCGCACCACCACGCCTGGCTAATTTTTTATTTTTGTAGAAATGGGGTATTGCTTTGTTGCCCGTGCTGGCTTCAGCCTTCTGGTTTCAAGC
AGTCCTCCTGCCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGTGCCCAACCCAGAAATACACCCTTTCTGTGCTGTTTTCTCAGCAGGG
TGTGAGCTCACGGGATACGGTCCTGCCAGACTGGCCCTCATAGCTGGTCATGTGCCAGTCAGAGCTGGGTGGGGCTTGCAGGTCCCGGAAGGTGGTGGTC
TTGACCTGGCAGCAGATGCTTAAAGAATGCCTAAGGTGGGTGGCAGTTGGGGAGTTCAAGGGTGAATGAGGCCAGGGCAGCCCCCAGGAGCTGAGGCCAA
CTCTTTGAGTCAGGACTGTGCCGTGTGCCCAGGGCCTTGCATGTGTGGGCCCTCGAGTGATTTCTACTGGCAGGCTGAAAGCCCTGTGAGGGGCGGCTGT
GGGCGGAGGCCACGCAGGAAGAGTGCTTAGGAGTAACTTGTTTCTAACACCTGTGTGCTGAGTGCCAATGCTGGGTGTGGTGTTATGATATATATTGGTT
TTCATCCAGCATTCCTGACTCGTAACTCTCATAGTCCTTGTTCCAGTCTTTGTTAGAATACTGGGTATGTTAGGGCTTGGGACAGGCCTCTGACCTCTGG
GTATCCTTTCACTAATGTTCGCCCACCTTTTTCACAGTGGGTCCTAAAGACCTTCCCATGAGAGGGTCTCAATCCTAGGGGAAGGAATGTTGATGTCATG
AACCTTCCATAAAAACCCAAGAGGACAGGGTTCAGAGAGCTTCTGGATAGCTGAACACCTGGCACTTCCTGGAGTGTGGCGTGCCCAGGGAGGGCACGGA
AGCTCTGCACTCCTTCCCCTTCCCTCATTCCTTGCTCTATGTGCATCTCTTCATCTGTATCCTTTGCGATATCCTTTATAATAAACCGGTAAACATAAGT
AA
  • refseq_TYSND1.F1 (forward primer)
  • refseq_TYSND1.R1 (reverse primer)
  • Multiple exon skipping

Frame 0

NRAR*GRRESELAPLASSCGWR*AASAGPGRGP
RSLACCFSEKLPSVRPRGHEKAVGVCHEGGRAGG
LHGERLPGRTARGGPVELQRGNPEP*PGPGALP
RGHLRPLPASWQRSPDRGRRRLPAWRQLQGRPA
PARAVGPNGRGSRGRRGAGPPRAVHAPVREPRAR
PTCPVPRASPAAPASC*AAAAAELPGLLGPLRA
PLRGRGSGTVALLERGAG*RSVGGRGGGSTESA
GLVCAAGRAARPGGGGGGARASHGGVASRGRAQG
CAIAGLRLPFRRLLPRHLSQHAELRGAQQRGRP
TAAYRRTLPARHRGRRRVHRAARGGAGGAGGGA
ALLEGRRMGGLHAALRRRPPFPRRPRRASPPAAQ
HRCPGRPSAARGGRPVGSAPPRLRAPVGSRGSV
GGVRHRMGLRSGCGTPPCSDLSARVPSGSSQGP
GALHHPQECGHLGPCGICHSGDMSL*HSSGEPGG
GPG*CPHPCAR*ALP*RRGCECGGLWRLWPVLR
ALGDLRHPFGCGAGEWHARNAADHVCCAQRLQW
GTPLLQPLRKPPW
HNHQQHPGQ*YGGHLPPPELQ
HSHHGAPAGPAAVQPDPRPRWPP*AGPRC*ASQ
GGVAVAAAPGRGPAEQALRLCYHLWKEE*PFSA
VGSDVEVTVASGFRAQPLQGPRLPLISTH*LQTG
LWALGQTSLQPHGSLTWQPVLGCFLEPPVLCPL
ALDSAVLFFLLGSPLQLHRSSGPDR*IPAGRQA
RAWFCVCSPEGHRHPGASMGPWLLSASQSESGLT
KDSASLASQQKPCSEDQRQKGQKQECLLLCQAH
GQCRQIPEGQHSWVFICQQGRS*HCAFIFQPTA
WVSGILRGRTCLVGAWE*T*SIEKPLYLYIKLFL
FFRS*TGNRQVPGKETHPFLFFFFFSLELWSCS
LTQAGVQCCDHSSLQPQTPGLQETSCLSLLNSW
DYSRAPPRLANFLFL*KWGIALLPVLASAFWFQA
VLLPQLPKVLGLQV*ATVPNPEIHPFCAVFSAG
CELTGYGPARLALIAGHVPVRAGWGLQVPEGGG
LDLAADA*RMPKVGGSWGVQG*MRPGQPPGAEAN
SLSQDCAVCPGPCMCGPSSDFYWQAESPVRGGC
GRRPRRKSA*E*LVSNTCVLSANAGCGVMIYIG
FHPAFLTRNSHSPCSSLC*NTGYVRAWDRPLTSG
YPFTNVRPPFSQWVLKTFP*EGLNPRGRNVDVM
NLP*KPKRTGFRELLDS*TPGTSWSVACPGRAR
KLCTPSPSLIPCSMCISSSVSFAISFIINR*T*V

Frame 1

IGLDEEDVSQSLRLSLPAVGGARQLQPDRVGVL
AR*LAVSRRSSRVSGLEAMRRQWGSAMRAAEQA
GCMVSASRAGQPEAGPWSCSGVILSRSPGLVLCH
GGIFVPFLRAGSEVLTAAGAVFLPGDSCRDDLR
LHVQWAPTAAGPGGGAERGRPGLCTPQCASLEP
GPPAPSRGRPLQPRLPAELLLLLSCPAFWAHFAR
LFGDEAAEQWRFSSAARDDEVSEDEEADQLRAL
GWFALLGVRLGQEEVEEERGPAMAVSPLGAVPK
GAPLLVCGSPFGAFCPDIFLNTLSCGVLSNVAGP
LLLTDARCLPGTEGGGVFTARPAGALVALVVAP
LCWKAGEWVGFTLLCAAAPLFRAARDALHRLPH
STAALAALLPPEVGVPWGLPLRDSGPLWAAAAVL
VECGTVWGSGVAVAPRLVVTCRHVSPREAARVL
VRSTTPKSVAIWGRVVFATQETCPYDIAVVSLE
EDLDDVPIPVPAEHFHEGEAVSVVGFGVFGQSCG
PSVTSGILSAVVQVNGTPVMLQTTCAVHSGSSG
GPLFSNHSGNLL
GIITSNTRDNNTGATYPHLNF
SIPITVLQPALQQYSQTQDLGGLRELDRAAEPVR
VVWRLQRPLAEAPRSKL*GCVTTFGKKSDLFLL
*EVMLR*RWPQDSGPSPCRGPGCLSSPPTDCRL
GFGLWGKLLFSPMDP*PGSPFWGAFLSPQFSVP*
H*TQLYCFSFWGAHSNCTEVLGLTGRFQLEGRP
VPGFASVPLRAIVILELQWGLGSCLPLSQSQG*
QRTQLP*HLSRNLALKTRDRRDRNRSASCCARPM
GSAGRSLKVSTPGSSYANRGALDTVPSFSSPQP
GSQGS*GVEHVWLGLGNKHDLLKNLCIYISNCF
FFSGVELGIGKYQAKKHTLSFFFFFFL*SCGLAL
SPRLECSVAITAHCSLKLLGSRRPPASAS*IAG
TTVAHHHAWLIFYFCRNGVLLCCPCWLQPSGFK
QSSCLSFPKCWDYRCEPLCPTQKYTLSVLFSQQG
VSSRDTVLPDWPS*LVMCQSELGGACRSRKVVV
LTWQQMLKECLRWVAVGEFKGE*GQGSPQELRP
TL*VRTVPCAQGLACVGPRVISTGRLKAL*GAAV
GGGHAGRVLRSNLFLTPVC*VPMLGVVL*YILV
FIQHS*LVTLIVLVPVFVRILGMLGLGTGL*PL
GILSLMFAHLFHSGS*RPSHERVSILGEGMLMS*
TFHKNPRGQGSESFWIAEHLALPGVWRAQGGHG
SSALLPLPSFLALCASLHLYPLRYPL**TGKHK
*

Frame 2

SGSMRKT*VRACASRFQLWVALGSFSRTG*GSS
LASLLFLGEAPECPA*RP*EGSGGLP*GRPSRR
AAW*APPGPDSPRRARGAAAG*S*AVARAWCFA
TGASSSPSCELAAKS*PRPAPSSCLATVAGTTCA
CTCSGPQRPRVPGAARSGAAQGCARPSARASSP
AHLPRPAGVPCSPGFLLSCCCC*AARPSGPTSR
ASSGTRQRNSGASRARRGMTKCRRTRRRIN*ERW
AGLRCWACG*ARRRWRRSAGQPWRCRLSGPCPR
VRHCWSAAPLSAPSAPTSFSTR*AAGCSATWPA
HCCLPTHAACPAPRAAACSPRGPRGRWWRWWWRR
SVGRPANGWASRCSAPPPPFSAPPATRFTACRT
APLPWPPFCRQRWASRGVCPSETPGPCGQPRQC
WWSAAPYGAPEWLWHPAL**PVGTCPLGKQPGSW
CAPPPPRVWPSGAVWYLPLRRHVPMT*QW*AWR
RTWMMSPSLCPLSTSMKARL*VWWALASLASLA
GPR*PQASFRLWCR*MARP*CCRPRVLCTAAPVG
DPSSPTTQETSL
A*SPATPGTIIRGPPTPT*TS
AFPSRCSSRPCSSTARPKT*VASVSWTALLSQS
GWCGGCSGPWQRPRGASSEAVLPPLERRVTFFCC
RK*C*GDGGLRIQGPAPAGAQAASHLHPLTADW
ALGSGANFSSAPWILNLAARFGVLS*APSSLSP
STRLSCIVFPSGEPTPTAQKFWA*QVDSSWKAGP
CLVLRLFP*GPSSSWSFNGALAPVCLSVRVRAD
KGLSFLSISAETLL*RPETEGTETGVPPAVPGP
WAVQADP*RSALLGLHMPTGALLTLCLHFPAHSL
GLRDLEG*NMSGWGLGINMIY*KTSVFIYQIVS
FFQELNWE*ASTRQRNTPFPFFFFFFFRAVVLL
SHPGWSAVLRSQLTAASNSWAPGDLLPQPPE*LG
LQSRTTTPG*FFIFVEMGYCFVARAGFSLLVSS
SPPASASQSAGITGVSHCAQPRNTPFLCCFLSR
V*AHGIRSCQTGPHSWSCASQSWVGLAGPGRWWS
*PGSRCLKNA*GGWQLGSSRVNEARAAPRS*GQ
LFESGLCRVPRALHVWALE*FLLAG*KPCEGRL
WAEATQEECLGVTCF*HLCAECQCWVWCYDIYWF
SSSIPDS*LS*SLFQSLLEYWVC*GLGQASDLW
VSFH*CSPTFFTVGPKDLPMRGSQS*GKEC*CH
EPSIKTQEDRVQRASG*LNTWHFLECGVPREGTE
ALHSFPFPHSLLYVHLFICILCDILYNKPVNIS

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