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Sequences

Sequence NM_001034956

AGCAGTTCAGAGCCCCAGTTGCAGACGACTTGTCCTGCCACCACCATGAGTTCTGAATGTGATGGTGGTTCCAAAGCTGTGATGAATGGCTTGGCACCTG GCAGCAATGGGCAAGACAAAGCAACTGCCGACCCTTTACGCGCACGCTCTATTTCTGCTGTTAAAATCATTCCTGTGAAGACAGTGAAAAACGCCTCAGG CCTAGTTCTCCCTACAGACATGGATCTTACAAAAATCTGCACTGGGAAGGGAGCGGTGACTCTCCGGGCCTCGTCTTCCTACAGGGAAACCCCAAGCAGT AGCCCTGCGAGCCCTCAGGAAACCCGGCAACACGAAAGCAAACCAGGTCTGGAGCCAGAGCCTTCTTCAGCAGATGAGTGGAGGCTTTCTTCCAGTGCTG ATGCCAATGGAAATGCCCAGCCCTCTTCACTCGCTGCCAAGGGCTACAGAAGTGTGCATCCCAACCTTCCTTCTGACAAGTCCCAGAGGTGGCCCCACCA CAGCCAGCCAGCCCGCGCCTCTGGCTCCTTTGCCCCCATTAGCCAGACGCCACCATCCTTCTCACCACCACCTCCGCTGGTCCCTCCTGCCCCGGAGGAC CTCCGCAGAGTCTCGGAGCCTGACCTCACGGGAGCTGTTTCGAGTACCGATTCCAGTCCTCTACTAAATGAAGTTTCTTCTTCCCTTATTGGAACTGATT CCCAAGCCTTTCCATCAGTTAGCAAGCCTTCATCCGCCTATCCCTCCACAACGATTGTCAATCCTACTATTGTGCTCTTGCAACACAATCGAGAACAGCA AAAACGACTCAGTAGCCTTTCAGATCCTGTCTCAGAAAGAAGAGTGGGAGAGCAGGACTCAGCACCAACCCAGGAAAAACCCACCTCACCTGGCAAGGCT ATTGAAAAAAGAGCAAAGGATGACAGTAGGCGGGTGGTGAAGAGCACTCAGGACTTAAGCGATGTTTCCATGGATGAAGTGGGCATCCCACTCCGGAACA CTGAGAGATCAAAAGACTGGTACAAGACTATGTTTAAACAGATCCACAAACTGAACAGAGATGATGATTCAGATCTGTACTCTCCCAGATACTCATTTTC TGAAGACACAAAATCTCCCCTTTCTGTGCCTCGCTCAAAAAGTGAGATGAGCTACATTGATGGTGAGAAGGTAGTCAAGAGGTCGGCCACACTACCCCTC CCAGCCCGCTCTTCCTCACTGAAGTCAAGCTCAGAAAGAAATGACTGGGAACCCCCAGATAAGAAAGTAGACACAAGAAAATATCGTGCAGAGCCCAAGA GCATTTACGAATATCAGCCTGGCAAGTCTTCCGTTCTGACCAACGAAAAGATGAGTCGGGATATAAGCCCAGAAGAGATAGATTTAAAGAATGAACCTTG GTATAAATTCTTTTCGGAATTGGAGTTTGGGAAACCGCCTCCCAAAAAGATATGGGATTATACTCCTGGAGACTGCTCTATCCTTCCTAGAGAGGATAGA AAGAGCTCAGCCATCAGCCCTACTCCGGAAATTTCTTCAGAGACTCCTGGATATATATATTCTTCCAACTTCCATGCAGTGAAGAGGGAATCAGACGGGG CTCCTGGGGATCTCACTAGCTTGGAGAATGAGAGACAAATTTATAAAAGTGTCTTGGAAGGTGGTGACATCCCTCTTCAGGGCCTGAGTGGGCTCAAGCG ACCATCCAGCTCTGCTTCCACTAAAGATTCAGAATCGCCAAGACATTTTATACCAGCTGATTACTTGGAATCCACGGAAGAATTTATTCGAAGACGTCAT GATGATAAAGAGAAACTTTTAGCGGACCAGAGACGACTTAAACGCGAGCAAGAAGAGGCTGATATTGCAGCTCGACGCCACACAGGCGTCATTCCGACGC ACCATCAGTTTATCACTAATGAGCGCTTTGGGGACCTCCTCAATATAGACGATACTGCAAAAAGGAAATCTGGGTCAGAGATGAGACCTGCCAGAGCCAA ATTTGACTTTAAAGCTCAGACACTAAAGGAGCTTCCTCTGCAGAAGGGAGATATTGTTTACATTTATAAGCAAATTGATCAGAACTGGTATGAAGGAGAA CACCACGGCCGGGTGGGAATCTTCCCACGCACCTACATCGAGCTTCTTCCTCCTGCTGAGAAGGCACAGCCCAAAAAGTTGACACCAGTGCAGGTTTTGG AATATGGAGAAGCTATTGCTAAGTTTAACTTTAATGGTGATACACAAGTAGAAATGTCCTTCAGAAAGGGTGAGAGGATCACACTGCTCCGGCAGGTAGA TGAGAACTGGTACGAAGGGAGGATCCCGGGGACATCCCGACAAGGCATCTTCCCCATCACCTACGTGGATGTGATCAAGCGACCACTGGTGAAAAACCCT GTGGATTACATGGACCTGCCTTTCTCCTCCTCCCCAAGTCGCAGTGCCACTGCAAGCCCACAGCTTTCTCATCATTCATTGAGAGCAGGACCAGATCTCA CAGAATCTGAAAAGAGCTATGTGCAACCTCAAGCCCAGCAGCGAAGAGTCACCCCCGACAGGAGTCAAACCTCACAAGATTTATTTAGCTATCAAGCATT ATATAGCTATATACCACAGAATGATGATGAGTTGGAACTCCGCGATGGAGATATCGTTGATGTCATGGAAAAATGTGACGATGGATGGTTTGTTGGTACT TCAAGAAGGACAAAGCAGTTTGGTACTTTTCCAGGCAACTATGTAAAACCTTTGTATCTATAAGAAGACTGAAAACCATGGAGATTATTTTTATTGGAGG AGGAAGCATCATTCATGAACCGATCTTTTTAGTTGAGTCAGTAGGAAAATTAATACAGTGGATAAAGTAAGAAGCAAAAGACAGGGACAGAGAAGTGTTG TGTTTAAAACCCAAGCCTGTCTAAGGTTACTGTGTATTAGACAGGGCCGAACTAGTGTGCTGAGCAAAAAGAATTGAAGCAAATTGTATTTACTTAGCCG CTTCTGGGAGCCACTTCAGCCTTTCCCCTCCCCTCCACTTCTTGGGTAATCTGACCTGAAGCATAGTCCAGGAGCAGAGTTAGCCAGAAATGCCTCCTGC TGCCCCAGCCTTAGAGAGCTCCCATCTCAATCATTGAGCCTGAAGGCTTCAAGCCCAAGAATGCAACAAGACCCCCAGCCTACATTTCTCAGCTCCCCTG GAGCCAGCTGATCCTGTAACGCTGCTGGAGGTCAGTCTGAGCTACCAAGACTGTCCCTAGACAAAGGTGGAGTCCCCCACACTGCCCAAGACCAAATCCC TCACTCAACCTGCTGAGGTGTGGATGGGGAAACAGAGGCAAAACTGAGGCACCTGATGCATTCAGCCTGCTGTGCAGCAGTGCCATTGACTGCCCTGATG TTCAGAGAGAAACGCACACAAGGTTTGCCCATGAGAATTGGGGAGCAGATGGCCAAGCAGATAGGTTATGTCTGTTTTCTGAGTGATGAAGTCAGGAAGC CCTGTGGCTCTGGAGGCCACTTGTGGTTCATTCTTTTCCCATATCCTTGGCTTTTAGAAATGGTTACCTTCAGGACAGTGCAGCTGCATTTATCAGAGCA CTATTGCTAAGTTTTCTTTTCTGGCTTGTGTTTTTCTGGGACAGTTTAGAATTGGGAGGCCTATTCTCATAGAACACCAAAAATGATGTTCAGTGATTCA TTTAACATACACCAATGTACTCTGGCTGCTGGGGGGACAACCATAAGCAAGACATGCCCAGGGTTTGCCGTGGCTCCAGATCTACTCCCTGTAGGAGTTC AAGGATCACACAAACGGTAGTAACCAGGGTTGTGAATCTGAGTACACCCTGGCAAGGCTTCTCTTCAGACTGAAGCAGCAATTCTGCCACTACCAGCAGC AACCAGGACGTCTGTTCTTTGTGGGGGCCAGATCAGAAGAGAGAGGCCCCTGTGACGCCCGGGCTGCTTGGTCACAACTCTGTCCAATTCAAGGATGTTT ATCGGCCTCTCTTAGATCCTGAGTGAGACAAATACAGAAATGACCCATTCCCTGCCCACCAGAAACTCAGAGGTGATTGGGGAGACTGACACAGGAAAAT GAACTTAATCAAGAGAGACTGTGATATGTGCTAAGAAGGGTGTGAGGGAGGGAGAGATGAATTTTCCCTGGAGGGATCCTAGAAAGCATTGTCATATTGC CATCTCCATTAGCTCACTTTTAAACAACTAGGGTGCTGGAAGAACCTTTGTCTGAGGGTAGTTCATAGCTGGAAATACTTGGAATATTTTCCAGAGTCTC TAAACTCTCATCTTCCCCCACAGATACACATCCAAGCTCACAAATAGGAGTAGCAATTCTAGGTGGTAGGGTTGTGTACGGAACCCCTGGCTGTCTGCAT ATATCTCAGAATTACCCCAGGACCATTGTCCCAAAGTCTAGAGTCTTTACAGGTAGGCAAAATTTGTTTTCAATGCCTGTGCCTCAGCTGCTGTCACAAA TACCCATCTTAGGATCCCATCAGCTTCCCATCCCCCACCAGACAGCCACAGTACCCTCACTTTCTCCCTATTGTTCTTTCAAATCCTGTTCTCAGGAAAG AAACTGCCACTAATTCATTCACACTAAGGTGTAAATGATTGATAATAGGAATGAGTTACCTCTTCCCACAGACATTTGTTTTTAAGTATGACAGAGCAGG GCCTTAATCCCAAGGGAAAAGGTTATGGAACTGGAGGGGGTGAGCTTTCTGGGTAGAAGGAGACTTCCTGAATTTCCTTAAAACCCAGTAAGAGTAAGAC CTGTTGTTTTGGAAGGTCTGCTCCACCATCTAAGAGCACTGTTTTTTTTTTTTTGTTGTTGTTGTTGTTTTACGGTCTCTGAGGGAATATAGTAAAAATG CATATGCACGTGCAATTTGCACGGCAGCATTTCACCGATTGTGGACTGTATTGGCTAATGTGTTTCCTGGTCTTTAGATGCAAACCATTAATAACACTAT CTTATCTCATAGTTTTTTCAGGGGTGCTTCTTGATTAGTAGGGAATTTTGAACACCTCTTTAAATACAGCTAGAAAATAAAACCAATTTGTAAAGCCACA TTTGCATATGATGCCAGCCTCACGCATTTGTATATCTCCAGAAATTCAGGTATGCCTCACCAATTTGCCCGTCTTTAATAAAATCTTGTGTTAAAATTTG CATCACGTCGCCTTCCTATGTATGACGAAACAAGAAACAGAGATTTCCAATTGCTCTTTTGTCTTCAGACATTTAGTAATATAAAGTACCTATTTTTATG CTGAAATGTTTATACAGGTTTATTAATAGCAAGTGCAACTAACTGGCGGCATGCCTTGCAACACATTTTGATATATTAGCCATGCTTCCGGGTAAAGGCA AGCCCCAAACTCCTTATCTTTTGCAGTCTCTCTGGGATCAGTAAAAGAAAAAAAAAATAATGTGCTTAAGAAGTGGGACTGTAAATATGTATATTTAACT TTGTATAGCCCATGTACCTACCTTGTATAGAAAAATAATTTTAAAAATTTGAATGGAAGGGGGTAAAGGAAGTCATGAAGTTTTTTTGCATTTTTATTTA AATGAAGGAATTCCAAATAACTCACCTACAGATTTTTAGCACAAAAATAGCCATTGTAAAGTGTTAAAATTTACGATAAGTATTCTATTGGGGAGGAAAG GTAACTCTGATCTCAGTTACAGTTTTTTTTTCCTTTTTAATTTCATTATTTTGGGTTTTTGGTTTTTGCAGTCCTATTTATCTGCAGTCGTATTAAGTCC TATTGCTAGAATAGGTTACTACAAAAAAGGTTATATTCTGAAAGAAAAATAACTGACATTATATATAACCAATTAATTTAAAGTATTGCCATTTAAATTA CACACTGAGAGCATGTCCTATGCAGACATAGATTTTTCTGTTCATTTATTTTTCTTCATTGCAGTGGATTGATTTGATAAATAGATGTGTTGAATTACTA CATTTGCTGTACATATTATTTAATAAACTTTATTCAGAATTGCGTGGCA

refseq_SORBS1.F1 (forward primer)
refseq_SORBS1.R1 (reverse primer)
Alternative acceptor

Frame 0

SSSEPQLQTTCPATTMSSECDGGSKAVMNGLAP GSNGQDKATADPLRARSISAVKIIPVKTVKNASG LVLPTDMDLTKICTGKGAVTLRASSSYRETPSS SPASPQETRQHESKPGLEPEPSSADEWRLSSSA DANGNAQPSSLAAKGYRSVHPNLPSDKSQRWPHH SQPARASGSFAPISQTPPSFSPPPPLVPPAPED LRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTD SQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQ KRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKA IEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRN TERSKDWYKTMFKQIHKLNRDDDSDLYSPRYSFS EDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPL PARSSSLKSSSERNDWEPPDKKVDTRKYRAEPK SIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPW YKFFSELEFGKPPPKKIWDYTPGDCSILPREDR KSSAISPTPEISSETPGYIYSSNFHAVKRESDG APGDLTSLENERQIYKSVLEGGDIPLQGLSGLKR PSSSASTKDSESPRHFIPADYLESTEEFIRRRH DDKEKLLADQRRLKREQEEADIAARRHTGVIPT HHQFITNERFGDLLNIDDTAKRKSGSEMRPARAK FDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGE HHGRVGIFPRTYIELLPPAEKAQPKKLTPVQVL EYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVD ENWYEGRIPGTSRQGIFPITYVDVIKRPLVKNP VDYMDLPFSSSPSRSATASPQLSHHSLRAGPDL TESEKSYVQPQAQQRRVTPDRSQTSQDLFSYQAL YSYIPQNDDELELRDGDIVDVMEKCDDGWFVGT SRRTKQFGTFPGNYVKPLYL*ED*KPWRLFLLE EEASFMNRSF*LSQ*EN*YSG*SKKQKTGTEKCC V*NPSLSKVTVY*TGPN*CAEQKELKQIVFT*P LLGATSAFPLPSTSWVI*PEA*SRSRVSQKCLL LPQP*RAPISIIEPEGFKPKNATRPPAYISQLPW SQLIL*RCWRSV*ATKTVPRQRWSPPHCPRPNP SLNLLRCGWGNRGKTEAPDAFSLLCSSAIDCPD VQRETHTRFAHENWGADGQADRLCLFSE**SQEA LWLWRPLVVHSFPISLAFRNGYLQDSAAAFIRA LLLSFLFWLVFFWDSLELGGLFS*NTKNDVQ*F I*HTPMYSGCWGDNHKQDMPRVCRGSRSTPCRSS RITQTVVTRVVNLSTPWQGFSSD*SSNSATTSS NQDVCSLWGPDQKREAPVTPGLLGHNSVQFKDV YRPLLDPE*DKYRNDPFPAHQKLRGDWGD*HRKM NLIKRDCDMC*EGCEGGRDEFSLEGS*KALSYC HLH*LTFKQLGCWKNLCLRVVHSWKYLEYFPES LNSHLPPQIHIQAHK*E*QF*VVGLCTEPLAVCI YLRITPGPLSQSLESLQVGKICFQCLCLSCCHK YPS*DPISFPSPTRQPQYPHFLPIVLSNPVLRK ETATNSFTLRCK*LIIGMSYLFPQTFVFKYDRAG P*SQGKRLWNWRG*AFWVEGDFLNFLKTQ*E*D LLFWKVCSTI*EHCFFFFVVVVVLRSLREYSKN AYARAICTAAFHRLWTVLANVFPGL*MQTINNTI LSHSFFRGAS*LVGNFEHLFKYS*KIKPICKAT FAYDASLTHLYISRNSGMPHQFARL**NLVLKF ASRRLPMYDETRNRDFQLLFCLQTFSNIKYLFLC *NVYTGLLIASATNWRHALQHILIY*PCFRVKA SPKLLIFCSLSGISKRKKK*CA*EVGL*ICIFN FV*PMYLPCIEK*F*KFEWKGVKEVMKFFCIFI* MKEFQITHLQIFSTKIAIVKC*NLR*VFYWGGK VTLISVTVFFSFLISLFWVFGFCSPIYLQSY*V LLLE*VTTKKVIF*KKNN*HYI*PINLKYCHLNY TLRACPMQT*IFLFIYFSSLQWIDLINRCVELL HLLYILFNKLYSELRG

Frame 1

AVQSPSCRRLVLPPP*VLNVMVVPKL**MAWHL AAMGKTKQLPTLYAHALFLLLKSFL*RQ*KTPQ A*FSLQTWILQKSALGRER*LSGPRLPTGKPQAV ALRALRKPGNTKANQVWSQSLLQQMSGGFLPVL MPMEMPSPLHSLPRATEVCIPTFLLTSPRGGPT TASQPAPLAPLPPLARRHHPSHHHLRWSLLPRRT SAESRSLTSRELFRVPIPVLY*MKFLLPLLELI PKPFHQLASLHPPIPPQRLSILLLCSCNTIENS KNDSVAFQILSQKEEWESRTQHQPRKNPPHLARL LKKEQRMTVGGW*RALRT*AMFPWMKWASHSGT LRDQKTGTRLCLNRSTN*TEMMIQICTLPDTHF LKTQNLPFLCLAQKVR*ATLMVRR*SRGRPHYPS QPALPH*SQAQKEMTGNPQIRK*TQENIVQSPR AFTNISLASLPF*PTKR*VGI*AQKR*I*RMNL GINSFRNWSLGNRLPKRYGIILLETALSFLERIE RAQPSALLRKFLQRLLDIYILPTSMQ*RGNQTG LLGISLAWRMRDKFIKVSWKVVTSLFRA*VGSS DHPALLPLKIQNRQDILYQLITWNPRKNLFEDVM MIKRNF*RTRDDLNASKKRLILQLDATQASFRR TISLSLMSALGTSSI*TILQKGNLGQR*DLPEP NLTLKLRH*RSFLCRREILFTFISKLIRTGMKEN TTAGWESSHAPTSSFFLLLRRHSPKS*HQCRFW NMEKLLLSLTLMVIHK*KCPSERVRGSHCSGR* MRTGTKGGSRGHPDKASSPSPTWM*SSDHW*KTL WITWTCLSPPPQVAVPLQAHSFLIIH*EQDQIS QNLKRAMCNLKPSSEESPPTGVKPHKIYLAIKH YIAIYHRMMMSWNSAMEISLMSWKNVTMDGLLVL QEGQSSLVLFQATM*NLCIYKKTENHGDYFYWR RKHHS*TDLFS*VSRKINTVDKVRSKRQGQRSV VFKTQACLRLLCIRQGRTSVLSKKN*SKLYLLSR FWEPLQPFPSPPLLG*SDLKHSPGAELARNASC CPSLRELPSQSLSLKASSPRMQQDPQPTFLSSP GAS*SCNAAGGQSELPRLSLDKGGVPHTAQDQIP HSTC*GVDGETEAKLRHLMHSACCAAVPLTALM FREKRTQGLPMRIGEQMAKQIGYVCFLSDEVRK PCGSGGHLWFILFPYPWLLEMVTFRTVQLHLSEH YC*VFFSGLCFSGTV*NWEAYSHRTPKMMFSDS FNIHQCTLAAGGTTISKTCPGFAVAPDLLPVGV QGSHKR**PGL*I*VHPGKASLQTEAAILPLPAA TRTSVLCGGQIRRERPL*RPGCLVTTLSNSRMF IGLS*ILSETNTEMTHSLPTRNSEVIGETDTGK *T*SRETVICAKKGVREGEMNFPWRDPRKHCHIA ISISSLLNN*GAGRTFV*G*FIAGNTWNIFQSL *TLIFPHRYTSKLTNRSSNSRW*GCVRNPWLSA YISELPQDHCPKV*SLYR*AKFVFNACASAAVTN THLRIPSASHPPPDSHSTLTFSLLFFQILFSGK KLPLIHSH*GVND***E*VTSSHRHLFLSMTEQ GLNPKGKGYGTGGGELSG*KETS*ISLKPSKSKT CCFGRSAPPSKSTVFFFLLLLLFYGL*GNIVKM HMHVQFARQHFTDCGLYWLMCFLVFRCKPLITL SYLIVFSGVLLD**GILNTSLNTARK*NQFVKPH LHMMPASRICISPEIQVCLTNLPVFNKILC*NL HHVAFLCMTKQETEISNCSFVFRHLVI*STYFY AEMFIQVY**QVQLTGGMPCNTF*YISHASG*RQ APNSLSFAVSLGSVKEKKNNVLKKWDCKYVYLT LYSPCTYLV*KNNFKNLNGRG*RKS*SFFAFLF K*RNSK*LTYRFLAQK*PL*SVKIYDKYSIGEER *L*SQLQFFFPF*FHYFGFLVFAVLFICSRIKS YC*NRLLQKRLYSERKITDIIYNQLI*SIAI*I TH*EHVLCRHRFFCSFIFLHCSGLI**IDVLNYY ICCTYYLINFIQNCVA

Frame 2

QFRAPVADDLSCHHHEF*M*WWFQSCDEWLGTW QQWARQSNCRPFTRTLYFCC*NHSCEDSEKRLR PSSPYRHGSYKNLHWEGSGDSPGLVFLQGNPKQ *PCEPSGNPATRKQTRSGARAFFSR*VEAFFQC* CQWKCPALFTRCQGLQKCASQPSF*QVPEVAPP QPASPRLWLLCPH*PDATILLTTTSAGPSCPGG PPQSLGA*PHGSCFEYRFQSSTK*SFFFPYWN*F PSLSIS*QAFIRLSLHNDCQSYYCALATQSRTA KTTQ*PFRSCLRKKSGRAGLSTNPGKTHLTWQG Y*KKSKG*Q*AGGEEHSGLKRCFHG*SGHPTPEH *EIKRLVQDYV*TDPQTEQR**FRSVLSQILIF *RHKISPFCASLKK*DELH*W*EGSQEVGHTTP PSPLFLTEVKLRKK*LGTPR*ESRHKKISCRAQE HLRISAWQVFRSDQRKDESGYKPRRDRFKE*TL V*ILFGIGVWETASQKDMGLYSWRLLYPS*RG* KELSHQPYSGNFFRDSWIYIFFQLPCSEEGIRRG SWGSH*LGE*ETNL*KCLGRW*HPSSGPEWAQA TIQLCFH*RFRIAKTFYTS*LLGIHGRIYSKTS ***RETFSGPETT*TRARRG*YCSSTPHRRHSDA PSVYH**ALWGPPQYRRYCKKEIWVRDETCQSQ I*L*SSDTKGASSAEGRYCLHL*AN*SELV*RR TPRPGGNLPTHLHRASSSC*EGTAQKVDTSAGFG IWRSYC*V*L*W*YTSRNVLQKG*EDHTAPAGR *ELVRREDPGDIPTRHLPHHLRGCDQATTGEKP CGLHGPAFLLLPKSQCHCKPTAFSSFIESRTRSH RI*KELCATSSPAAKSHPRQESNLTRFI*LSSI I*LYTTE***VGTPRWRYR*CHGKM*RWMVCWY FKKDKAVWYFSRQLCKTFVSIRRLKTMEIIFIGG GSIIHEPIFLVESVGKLIQWIK*EAKDRDREVL CLKPKPV*GYCVLDRAELVC*AKRIEANCIYLA ASGSHFSLSPPLHFLGNLT*SIVQEQS*PEMPPA APALESSHLNH*A*RLQAQECNKTPSLHFSAPL EPADPVTLLEVSLSYQDCP*TKVESPTLPKTKS LTQPAEVWMGKQRQN*GT*CIQPAVQQCH*LP*C SERNAHKVCP*ELGSRWPSR*VMSVF*VMKSGS PVALEATCGSFFSHILGF*KWLPSGQCSCIYQS TIAKFSFLACVFLGQFRIGRPILIEHQK*CSVIH LTYTNVLWLLGGQP*ARHAQGLPWLQIYSL*EF KDHTNGSNQGCESEYTLARLLFRLKQQFCHYQQ QPGRLFFVGARSEERGPCDARAAWSQLCPIQGCL SASLRS*VRQIQK*PIPCPPETQR*LGRLTQEN ELNQERL*YVLRRV*GRER*IFPGGILESIVIL PSPLAHF*TTRVLEEPLSEGSS*LEILGIFSRVS KLSSSPTDTHPSSQIGVAILGGRVVYGTPGCLH ISQNYPRTIVPKSRVFTGRQNLFSMPVPQLLSQ IPILGSHQLPIPHQTATVPSLSPYCSFKSCSQER NCH*FIHTKV*MIDNRNELPLPTDICF*V*QSR ALIPREKVMELEGVSFLGRRRLPEFP*NPVRVR PVVLEGLLHHLRALFFFFCCCCCFTVSEGI**KC ICTCNLHGSISPIVDCIG*CVSWSLDANH**HY LIS*FFQGCFLISREF*TPL*IQLENKTNL*SH ICI*CQPHAFVYLQKFRYASPICPSLIKSCVKIC ITSPSYV*RNKKQRFPIALLSSDI**YKVPIFM LKCLYRFINSKCN*LAACLATHFDILAMLPGKG KPQTPYLLQSLWDQ*KKKKIMCLRSGTVNMYI*L CIAHVPTLYRKIILKI*MEGGKGSHEVFLHFYL NEGIPNNSPTDF*HKNSHCKVLKFTISILLGRK GNSDLSYSFFFLFNFIILGFWFLQSYLSAVVLSP IARIGYYKKGYILKEK*LTLYITN*FKVLPFKL HTESMSYADIDFSVHLFFFIAVD*FDK*MC*IT TFAVHII**TLFRIAW

Sequence NM_001034954

AGCAGTTCAGAGCCCCAGTTGCAGACGACTTGTCCTGCCACCACCATGAGTTCTGAATGTGATGGTGGTTCCAAAGCTGTGATGAATGGCTTGGCACCTG GCAGCAATGGGCAAGACAAAGCAACTGCCGACCCTTTACGCGCACGCTCTATTTCTGCTGTTAAAATCATTCCTGTGAAGACAGTGAAAAACGCCTCAGG CCTAGTTCTCCCTACAGACATGGATCTTACAAAAATCTGCACTGGGAAGGGAGCGGTGACTCTCCGGGCCTCGTCTTCCTACAGGGAAACCCCAAGCAGT AGCCCTGCGAGCCCTCAGGAAACCCGGCAACACGAAAGCAAACCAGGTCTGGAGCCAGAGCCTTCTTCAGCAGATGAGTGGAGGCTTTCTTCCAGTGCTG ATGCCAATGGAAATGCCCAGCCCTCTTCACTCGCTGCCAAGGGCTACAGAAGTGTGCATCCCAACCTTCCTTCTGACAAGTCCCAGGATGCCACTTCCTC CAGTGCAGCCCAGCCGGAGGTAATAGTTGTCCCTCTCTACCTGGTTAATACTGACAGAGGGCAAGAAGGCACTGCCAGACCTCCAACACCTCTGGGGCCT CTTGGCTGCGTCCCCACAATCCCAGCGACTGCCTCTGCCGCCTCACCTCTGACCTTCCCGACTCTAGATGATTTCATTCCCCCTCATCTGCAGAGGTGGC CCCACCACAGCCAGCCAGCCCGCGCCTCTGGCTCCTTTGCCCCCATTAGCCAGACGCCACCATCCTTCTCACCACCACCTCCGCTGGTCCCTCCTGCCCC GGAGGACCTCCGCAGAGTCTCGGAGCCTGACCTCACGGGAGCTGTTTCGAGTACCGATTCCAGTCCTCTACTAAATGAAGTTTCTTCTTCCCTTATTGGA ACTGATTCCCAAGCCTTTCCATCAGTTAGCAAGCCTTCATCCGCCTATCCCTCCACAACGATTGTCAATCCTACTATTGTGCTCTTGCAACACAATCGAG AACAGCAAAAACGACTCAGTAGCCTTTCAGATCCTGTCTCAGAAAGAAGAGTGGGAGAGCAGGACTCAGCACCAACCCAGGAAAAACCCACCTCACCTGG CAAGGCTATTGAAAAAAGAGCAAAGGATGACAGTAGGCGGGTGGTGAAGAGCACTCAGGACTTAAGCGATGTTTCCATGGATGAAGTGGGCATCCCACTC CGGAACACTGAGAGATCAAAAGACTGGTACAAGACTATGTTTAAACAGATCCACAAACTGAACAGAGACACTCCTGAAGAAAACCCTTATTTCCCTACGT ACAAATTCCCTGAACTTCCTGAAATCCAGCAAACTTCCGAAGAGGACAATCCTTACACTCCCACCTACCAGTTTCCTGCATCTACTCCTAGTCCTAAATC TGAAGATGATGATTCAGATCTGTACTCTCCCAGATACTCATTTTCTGAAGACACAAAATCTCCCCTTTCTGTGCCTCGCTCAAAAAGTGAGATGAGCTAC ATTGATGGTGAGAAGGTAGTCAAGAGGTCGGCCACACTACCCCTCCCAGCCCGCTCTTCCTCACTGAAGTCAAGCTCAGAAAGAAATGACTGGGAACCCC CAGATAAGAAAGTAGACACAAGAAAATATCGTGCAGAGCCCAAGAGCATTTACGAATATCAGCCTGGCAAGTCTTCCGTTCTGACCAACGAAAAGATGAG TCGGGATATAAGCCCAGAAGAGATAGATTTAAAGAATGAACCTTGGTATAAATTCTTTTCGGAATTGGAGTTTGGGAAACCGCCTCCCAAAAAGATATGG GATTATACTCCTGGAGACTGCTCTATCCTTCCTAGAGAGGATAGAAAGACTAATCTAGACAAAGATCTCAGCCTCTGCCAGACAGAGTTAGAGGCAGATT TAGAAAAAATGGAGACGCTTAATAAAGCACCCAGTGCAAACGTGCCACAGAGCTCAGCCATCAGCCCTACTCCGGAAATTTCTTCAGAGACTCCTGGATA TATATATTCTTCCAACTTCCATGCAGTGAAGAGGGAATCAGACGGGGCTCCTGGGGATCTCACTAGCTTGGAGAATGAGAGACAAATTTATAAAAGTGTC TTGGAAGGTGGTGACATCCCTCTTCAGGGCCTGAGTGGGCTCAAGCGACCATCCAGCTCTGCTTCCACTAAAGATTCAGAATCGCCAAGACATTTTATAC CAGCTGATTACTTGGAATCCACGGAAGAATTTATTCGAAGACGTCATGATGATAAAGAGAAACTTTTAGCGGACCAGAGACGACTTAAACGCGAGCAAGA AGAGGCTGATATTGCAGCTCGACGCCACACAGGCGTCATTCCGACGCACCATCAGTTTATCACTAATGAGCGCTTTGGGGACCTCCTCAATATAGACGAT ACTGCAAAAAGGAAATCTGGGTCAGAGATGAGACCTGCCAGAGCCAAATTTGACTTTAAAGCTCAGACACTAAAGGAGCTTCCTCTGCAGAAGGGAGATA TTGTTTACATTTATAAGCAAATTGATCAGAACTGGTATGAAGGAGAACACCACGGCCGGGTGGGAATCTTCCCACGCACCTACATCGAGCTTCTTCCTCC TGCTGAGAAGGCACAGCCCAAAAAGTTGACACCAGTGCAGGTTTTGGAATATGGAGAAGCTATTGCTAAGTTTAACTTTAATGGTGATACACAAGTAGAA ATGTCCTTCAGAAAGGGTGAGAGGATCACACTGCTCCGGCAGGTAGATGAGAACTGGTACGAAGGGAGGATCCCGGGGACATCCCGACAAGGCATCTTCC CCATCACCTACGTGGATGTGATCAAGCGACCACTGGTGAAAAACCCTGTGGATTACATGGACCTGCCTTTCTCCTCCTCCCCAAGTCGCAGTGCCACTGC AAGCCCACAGTTTTCCAGTCACAGCAAGCTCATCACGCCAGCCCCCTCATCTCTGCCCCACTCCCGCCGAGCCCTGTCCCCCGAGATGCACGCTGTCACC TCTGAGTGGATCTCACTGACTGTGGGGGTCCCAGGCAGGCGTTCTCTGGCCCTGACCCCACCCTTGCCTCCTCTGCCAGAGGCTTCTATCTATAACACTG ACCACCTCGCCTTGTCACCAAGGGCCAGTCCCTCCCTGTCTCTCAGCCTCCCCCATTTGAGTTGGTCAGATCGTCCCACCCCACGATCAGTAGCTTCTCC ACTGGCCCTACCTTCCCCACACAAAACCTACTCCCTAGCACCTACTTCCCAGGCCTCCCTTCACATGAATGGAGACGGTGGTGTCCACACGCCATCTTCA GGCATCCACCAAGATAGCTTCTTGCAGCTGCCGCTGGGGAGCTCTGATAGTGTCATCTCCCAGCTTAGTGATGCCTTTAGCAGCCAGAGCAAGAGGCAGC CATGGCGCGAAGAGAGTGGACAATATGAGAGGAAAGCAGAGAGGGGGGCAGGCGAAAGAGGCCCTGGTGGACCCAAGATCTCTAAGAAGAGCTGCTTGAA GCCTTCAGACGTGGTCAGGTGCCTGAGTACTGAACAGAGACTCTCAGATCTCAACACCCCTGAGGAGAGCCGGCCCGGCAAGCCCCTGGGTAGCGCTTTT CCAGGAAGTGAGGCTGAGCAGACAGAGCGGCATAGAGGTGGCGAGCAGGCGGGGAGGAAAGCTGCTCGGAGAGGTGGGAGCCAGCAACCTCAAGCCCAGC AGCGAAGAGTCACCCCCGACAGGAGTCAAACCTCACAAGATTTATTTAGCTATCAAGCATTATATAGCTATATACCACAGAATGATGATGAGTTGGAACT CCGCGATGGAGATATCGTTGATGTCATGGAAAAATGTGACGATGGATGGTTTGTTGGTACTTCAAGAAGGACAAAGCAGTTTGGTACTTTTCCAGGCAAC TATGTAAAACCTTTGTATCTATAAGAAGACTGAAAACCATGGAGATTATTTTTATTGGAGGAGGAAGCATCATTCATGAACCGATCTTTTTAGTTGAGTC AGTAGGAAAATTAATACAGTGGATAAAGTAAGAAGCAAAAGACAGGGACAGAGAAGTGTTGTGTTTAAAACCCAAGCCTGTCTAAGGTTACTGTGTATTA GACAGGGCCGAACTAGTGTGCTGAGCAAAAAGAATTGAAGCAAATTGTATTTACTTAGCCGCTTCTGGGAGCCACTTCAGCCTTTCCCCTCCCCTCCACT TCTTGGGTAATCTGACCTGAAGCATAGTCCAGGAGCAGAGTTAGCCAGAAATGCCTCCTGCTGCCCCAGCCTTAGAGAGCTCCCATCTCAATCATTGAGC CTGAAGGCTTCAAGCCCAAGAATGCAACAAGACCCCCAGCCTACATTTCTCAGCTCCCCTGGAGCCAGCTGATCCTGTAACGCTGCTGGAGGTCAGTCTG AGCTACCAAGACTGTCCCTAGACAAAGGTGGAGTCCCCCACACTGCCCAAGACCAAATCCCTCACTCAACCTGCTGAGGTGTGGATGGGGAAACAGAGGC AAAACTGAGGCACCTGATGCATTCAGCCTGCTGTGCAGCAGTGCCATTGACTGCCCTGATGTTCAGAGAGAAACGCACACAAGGTTTGCCCATGAGAATT GGGGAGCAGATGGCCAAGCAGATAGGTTATGTCTGTTTTCTGAGTGATGAAGTCAGGAAGCCCTGTGGCTCTGGAGGCCACTTGTGGTTCATTCTTTTCC CATATCCTTGGCTTTTAGAAATGGTTACCTTCAGGACAGTGCAGCTGCATTTATCAGAGCACTATTGCTAAGTTTTCTTTTCTGGCTTGTGTTTTTCTGG GACAGTTTAGAATTGGGAGGCCTATTCTCATAGAACACCAAAAATGATGTTCAGTGATTCATTTAACATACACCAATGTACTCTGGCTGCTGGGGGGACA ACCATAAGCAAGACATGCCCAGGGTTTGCCGTGGCTCCAGATCTACTCCCTGTAGGAGTTCAAGGATCACACAAACGGTAGTAACCAGGGTTGTGAATCT GAGTACACCCTGGCAAGGCTTCTCTTCAGACTGAAGCAGCAATTCTGCCACTACCAGCAGCAACCAGGACGTCTGTTCTTTGTGGGGGCCAGATCAGAAG AGAGAGGCCCCTGTGACGCCCGGGCTGCTTGGTCACAACTCTGTCCAATTCAAGGATGTTTATCGGCCTCTCTTAGATCCTGAGTGAGACAAATACAGAA ATGACCCATTCCCTGCCCACCAGAAACTCAGAGGTGATTGGGGAGACTGACACAGGAAAATGAACTTAATCAAGAGAGACTGTGATATGTGCTAAGAAGG GTGTGAGGGAGGGAGAGATGAATTTTCCCTGGAGGGATCCTAGAAAGCATTGTCATATTGCCATCTCCATTAGCTCACTTTTAAACAACTAGGGTGCTGG AAGAACCTTTGTCTGAGGGTAGTTCATAGCTGGAAATACTTGGAATATTTTCCAGAGTCTCTAAACTCTCATCTTCCCCCACAGATACACATCCAAGCTC ACAAATAGGAGTAGCAATTCTAGGTGGTAGGGTTGTGTACGGAACCCCTGGCTGTCTGCATATATCTCAGAATTACCCCAGGACCATTGTCCCAAAGTCT AGAGTCTTTACAGGTAGGCAAAATTTGTTTTCAATGCCTGTGCCTCAGCTGCTGTCACAAATACCCATCTTAGGATCCCATCAGCTTCCCATCCCCCACC AGACAGCCACAGTACCCTCACTTTCTCCCTATTGTTCTTTCAAATCCTGTTCTCAGGAAAGAAACTGCCACTAATTCATTCACACTAAGGTGTAAATGAT TGATAATAGGAATGAGTTACCTCTTCCCACAGACATTTGTTTTTAAGTATGACAGAGCAGGGCCTTAATCCCAAGGGAAAAGGTTATGGAACTGGAGGGG GTGAGCTTTCTGGGTAGAAGGAGACTTCCTGAATTTCCTTAAAACCCAGTAAGAGTAAGACCTGTTGTTTTGGAAGGTCTGCTCCACCATCTAAGAGCAC TGTTTTTTTTTTTTTGTTGTTGTTGTTGTTTTACGGTCTCTGAGGGAATATAGTAAAAATGCATATGCACGTGCAATTTGCACGGCAGCATTTCACCGAT TGTGGACTGTATTGGCTAATGTGTTTCCTGGTCTTTAGATGCAAACCATTAATAACACTATCTTATCTCATAGTTTTTTCAGGGGTGCTTCTTGATTAGT AGGGAATTTTGAACACCTCTTTAAATACAGCTAGAAAATAAAACCAATTTGTAAAGCCACATTTGCATATGATGCCAGCCTCACGCATTTGTATATCTCC AGAAATTCAGGTATGCCTCACCAATTTGCCCGTCTTTAATAAAATCTTGTGTTAAAATTTGCATCACGTCGCCTTCCTATGTATGACGAAACAAGAAACA GAGATTTCCAATTGCTCTTTTGTCTTCAGACATTTAGTAATATAAAGTACCTATTTTTATGCTGAAATGTTTATACAGGTTTATTAATAGCAAGTGCAAC TAACTGGCGGCATGCCTTGCAACACATTTTGATATATTAGCCATGCTTCCGGGTAAAGGCAAGCCCCAAACTCCTTATCTTTTGCAGTCTCTCTGGGATC AGTAAAAGAAAAAAAAAATAATGTGCTTAAGAAGTGGGACTGTAAATATGTATATTTAACTTTGTATAGCCCATGTACCTACCTTGTATAGAAAAATAAT TTTAAAAATTTGAATGGAAGGGGGTAAAGGAAGTCATGAAGTTTTTTTGCATTTTTATTTAAATGAAGGAATTCCAAATAACTCACCTACAGATTTTTAG CACAAAAATAGCCATTGTAAAGTGTTAAAATTTACGATAAGTATTCTATTGGGGAGGAAAGGTAACTCTGATCTCAGTTACAGTTTTTTTTTCCTTTTTA ATTTCATTATTTTGGGTTTTTGGTTTTTGCAGTCCTATTTATCTGCAGTCGTATTAAGTCCTATTGCTAGAATAGGTTACTACAAAAAAGGTTATATTCT GAAAGAAAAATAACTGACATTATATATAACCAATTAATTTAAAGTATTGCCATTTAAATTACACACTGAGAGCATGTCCTATGCAGACATAGATTTTTCT GTTCATTTATTTTTCTTCATTGCAGTGGATTGATTTGATAAATAGATGTGTTGAATTACTACATTTGCTGTACATATTATTTAATAAACTTTATTCAGAA TTGCGTGGCA

refseq_SORBS1.F1 (forward primer)
refseq_SORBS1.R1 (reverse primer)
Alternative acceptor

Frame 0

SSSEPQLQTTCPATTMSSECDGGSKAVMNGLAP GSNGQDKATADPLRARSISAVKIIPVKTVKNASG LVLPTDMDLTKICTGKGAVTLRASSSYRETPSS SPASPQETRQHESKPGLEPEPSSADEWRLSSSA DANGNAQPSSLAAKGYRSVHPNLPSDKSQDATSS SAAQPEVIVVPLYLVNTDRGQEGTARPPTPLGP LGCVPTIPATASAASPLTFPTLDDFIPPHLQRW PHHSQPARASGSFAPISQTPPSFSPPPPLVPPAP EDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIG TDSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNR EQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPG KAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPL RNTERSKDWYKTMFKQIHKLNRDTPEENPYFPT YKFPELPEIQQTSEEDNPYTPTYQFPASTPSPKS EDDDSDLYSPRYSFSEDTKSPLSVPRSKSEMSY IDGEKVVKRSATLPLPARSSSLKSSSERNDWEP PDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMS RDISPEEIDLKNEPWYKFFSELEFGKPPPKKIW DYTPGDCSILPREDRKTNLDKDLSLCQTELEAD LEKMETLNKAPSANVPQSSAISPTPEISSETPGY IYSSNFHAVKRESDGAPGDLTSLENERQIYKSV LEGGDIPLQGLSGLKRPSSSASTKDSESPRHFI PADYLESTEEFIRRRHDDKEKLLADQRRLKREQE EADIAARRHTGVIPTHHQFITNERFGDLLNIDD TAKRKSGSEMRPARAKFDFKAQTLKELPLQKGD IVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPP AEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVE MSFRKGERITLLRQVDENWYEGRIPGTSRQGIF PITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATA SPQFSSHSKLITPAPSSLPHSRRALSPEMHAVT SEWISLTVGVPGRRSLALTPPLPPLPEASIYNT DHLALSPRASPSLSLSLPHLSWSDRPTPRSVASP LALPSPHKTYSLAPTSQASLHMNGDGGVHTPSS GIHQDSFLQLPLGSSDSVISQLSDAFSSQSKRQ PWREESGQYERKAERGAGERGPGGPKISKKSCLK PSDVVRCLSTEQRLSDLNTPEESRPGKPLGSAF PGSEAEQTERHRGGEQAGRKAARRGGSQQPQAQ QRRVTPDRSQTSQDLFSYQALYSYIPQNDDELEL RDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGN YVKPLYL*ED*KPWRLFLLEEEASFMNRSF*LS Q*EN*YSG*SKKQKTGTEKCCV*NPSLSKVTVY* TGPN*CAEQKELKQIVFT*PLLGATSAFPLPST SWVI*PEA*SRSRVSQKCLLLPQP*RAPISIIE PEGFKPKNATRPPAYISQLPWSQLIL*RCWRSV* ATKTVPRQRWSPPHCPRPNPSLNLLRCGWGNRG KTEAPDAFSLLCSSAIDCPDVQRETHTRFAHEN WGADGQADRLCLFSE**SQEALWLWRPLVVHSFP ISLAFRNGYLQDSAAAFIRALLLSFLFWLVFFW DSLELGGLFS*NTKNDVQ*FI*HTPMYSGCWGD NHKQDMPRVCRGSRSTPCRSSRITQTVVTRVVNL STPWQGFSSD*SSNSATTSSNQDVCSLWGPDQK REAPVTPGLLGHNSVQFKDVYRPLLDPE*DKYR NDPFPAHQKLRGDWGD*HRKMNLIKRDCDMC*EG CEGGRDEFSLEGS*KALSYCHLH*LTFKQLGCW KNLCLRVVHSWKYLEYFPESLNSHLPPQIHIQA HK*E*QF*VVGLCTEPLAVCIYLRITPGPLSQSL ESLQVGKICFQCLCLSCCHKYPS*DPISFPSPT RQPQYPHFLPIVLSNPVLRKETATNSFTLRCK* LIIGMSYLFPQTFVFKYDRAGP*SQGKRLWNWRG *AFWVEGDFLNFLKTQ*E*DLLFWKVCSTI*EH CFFFFVVVVVLRSLREYSKNAYARAICTAAFHR LWTVLANVFPGL*MQTINNTILSHSFFRGAS*LV GNFEHLFKYS*KIKPICKATFAYDASLTHLYIS RNSGMPHQFARL**NLVLKFASRRLPMYDETRN RDFQLLFCLQTFSNIKYLFLC*NVYTGLLIASAT NWRHALQHILIY*PCFRVKASPKLLIFCSLSGI SKRKKK*CA*EVGL*ICIFNFV*PMYLPCIEK* F*KFEWKGVKEVMKFFCIFI*MKEFQITHLQIFS TKIAIVKC*NLR*VFYWGGKVTLISVTVFFSFL ISLFWVFGFCSPIYLQSY*VLLLE*VTTKKVIF *KKNN*HYI*PINLKYCHLNYTLRACPMQT*IFL FIYFSSLQWIDLINRCVELLHLLYILFNKLYSE LRG

Frame 1

AVQSPSCRRLVLPPP*VLNVMVVPKL**MAWHL AAMGKTKQLPTLYAHALFLLLKSFL*RQ*KTPQ A*FSLQTWILQKSALGRER*LSGPRLPTGKPQAV ALRALRKPGNTKANQVWSQSLLQQMSGGFLPVL MPMEMPSPLHSLPRATEVCIPTFLLTSPRMPLP PVQPSRR**LSLSTWLILTEGKKALPDLQHLWGL LAASPQSQRLPLPPHL*PSRL*MISFPLICRGG PTTASQPAPLAPLPPLARRHHPSHHHLRWSLLP RRTSAESRSLTSRELFRVPIPVLY*MKFLLPLLE LIPKPFHQLASLHPPIPPQRLSILLLCSCNTIE NSKNDSVAFQILSQKEEWESRTQHQPRKNPPHL ARLLKKEQRMTVGGW*RALRT*AMFPWMKWASHS GTLRDQKTGTRLCLNRSTN*TETLLKKTLISLR TNSLNFLKSSKLPKRTILTLPPTSFLHLLLVLN LKMMIQICTLPDTHFLKTQNLPFLCLAQKVR*AT LMVRR*SRGRPHYPSQPALPH*SQAQKEMTGNP QIRK*TQENIVQSPRAFTNISLASLPF*PTKR* VGI*AQKR*I*RMNLGINSFRNWSLGNRLPKRYG IILLETALSFLERIERLI*TKISASARQS*RQI *KKWRRLIKHPVQTCHRAQPSALLRKFLQRLLD IYILPTSMQ*RGNQTGLLGISLAWRMRDKFIKVS WKVVTSLFRA*VGSSDHPALLPLKIQNRQDILY QLITWNPRKNLFEDVMMIKRNF*RTRDDLNASK KRLILQLDATQASFRRTISLSLMSALGTSSI*TI LQKGNLGQR*DLPEPNLTLKLRH*RSFLCRREI LFTFISKLIRTGMKENTTAGWESSHAPTSSFFL LLRRHSPKS*HQCRFWNMEKLLLSLTLMVIHK*K CPSERVRGSHCSGR*MRTGTKGGSRGHPDKASS PSPTWM*SSDHW*KTLWITWTCLSPPPQVAVPL QAHSFPVTASSSRQPPHLCPTPAEPCPPRCTLSP LSGSH*LWGSQAGVLWP*PHPCLLCQRLLSITL TTSPCHQGPVPPCLSASPI*VGQIVPPHDQ*LL HWPYLPHTKPTP*HLLPRPPFT*METVVSTRHLQ ASTKIASCSCRWGALIVSSPSLVMPLAARARGS HGAKRVDNMRGKQRGGQAKEALVDPRSLRRAA* SLQTWSGA*VLNRDSQISTPLRRAGPASPWVALF QEVRLSRQSGIEVASRRGGKLLGEVGASNLKPS SEESPPTGVKPHKIYLAIKHYIAIYHRMMMSWN SAMEISLMSWKNVTMDGLLVLQEGQSSLVLFQAT M*NLCIYKKTENHGDYFYWRRKHHS*TDLFS*V SRKINTVDKVRSKRQGQRSVVFKTQACLRLLCI RQGRTSVLSKKN*SKLYLLSRFWEPLQPFPSPPL LG*SDLKHSPGAELARNASCCPSLRELPSQSLS LKASSPRMQQDPQPTFLSSPGAS*SCNAAGGQS ELPRLSLDKGGVPHTAQDQIPHSTC*GVDGETEA KLRHLMHSACCAAVPLTALMFREKRTQGLPMRI GEQMAKQIGYVCFLSDEVRKPCGSGGHLWFILF PYPWLLEMVTFRTVQLHLSEHYC*VFFSGLCFSG TV*NWEAYSHRTPKMMFSDSFNIHQCTLAAGGT TISKTCPGFAVAPDLLPVGVQGSHKR**PGL*I *VHPGKASLQTEAAILPLPAATRTSVLCGGQIRR ERPL*RPGCLVTTLSNSRMFIGLS*ILSETNTE MTHSLPTRNSEVIGETDTGK*T*SRETVICAKK GVREGEMNFPWRDPRKHCHIAISISSLLNN*GAG RTFV*G*FIAGNTWNIFQSL*TLIFPHRYTSKL TNRSSNSRW*GCVRNPWLSAYISELPQDHCPKV *SLYR*AKFVFNACASAAVTNTHLRIPSASHPPP DSHSTLTFSLLFFQILFSGKKLPLIHSH*GVND ***E*VTSSHRHLFLSMTEQGLNPKGKGYGTGG GELSG*KETS*ISLKPSKSKTCCFGRSAPPSKST VFFFLLLLLFYGL*GNIVKMHMHVQFARQHFTD CGLYWLMCFLVFRCKPLITLSYLIVFSGVLLD* *GILNTSLNTARK*NQFVKPHLHMMPASRICISP EIQVCLTNLPVFNKILC*NLHHVAFLCMTKQET EISNCSFVFRHLVI*STYFYAEMFIQVY**QVQ LTGGMPCNTF*YISHASG*RQAPNSLSFAVSLGS VKEKKNNVLKKWDCKYVYLTLYSPCTYLV*KNN FKNLNGRG*RKS*SFFAFLFK*RNSK*LTYRFL AQK*PL*SVKIYDKYSIGEER*L*SQLQFFFPF* FHYFGFLVFAVLFICSRIKSYC*NRLLQKRLYS ERKITDIIYNQLI*SIAI*ITH*EHVLCRHRFF CSFIFLHCSGLI**IDVLNYYICCTYYLINFIQN CVA

Frame 2

QFRAPVADDLSCHHHEF*M*WWFQSCDEWLGTW QQWARQSNCRPFTRTLYFCC*NHSCEDSEKRLR PSSPYRHGSYKNLHWEGSGDSPGLVFLQGNPKQ *PCEPSGNPATRKQTRSGARAFFSR*VEAFFQC* CQWKCPALFTRCQGLQKCASQPSF*QVPGCHFL QCSPAGGNSCPSLPG*Y*QRARRHCQTSNTSGA SWLRPHNPSDCLCRLTSDLPDSR*FHSPSSAEVA PPQPASPRLWLLCPH*PDATILLTTTSAGPSCP GGPPQSLGA*PHGSCFEYRFQSSTK*SFFFPYW N*FPSLSIS*QAFIRLSLHNDCQSYYCALATQSR TAKTTQ*PFRSCLRKKSGRAGLSTNPGKTHLTW QGY*KKSKG*Q*AGGEEHSGLKRCFHG*SGHPT PEH*EIKRLVQDYV*TDPQTEQRHS*RKPLFPYV QIP*TS*NPANFRRGQSLHSHLPVSCIYS*S*I *R**FRSVLSQILIF*RHKISPFCASLKK*DEL H*W*EGSQEVGHTTPPSPLFLTEVKLRKK*LGTP R*ESRHKKISCRAQEHLRISAWQVFRSDQRKDE SGYKPRRDRFKE*TLV*ILFGIGVWETASQKDM GLYSWRLLYPS*RG*KD*SRQRSQPLPDRVRGRF RKNGDA**STQCKRATELSHQPYSGNFFRDSWI YIFFQLPCSEEGIRRGSWGSH*LGE*ETNL*KC LGRW*HPSSGPEWAQATIQLCFH*RFRIAKTFYT S*LLGIHGRIYSKTS***RETFSGPETT*TRAR RG*YCSSTPHRRHSDAPSVYH**ALWGPPQYRR YCKKEIWVRDETCQSQI*L*SSDTKGASSAEGRY CLHL*AN*SELV*RRTPRPGGNLPTHLHRASSS C*EGTAQKVDTSAGFGIWRSYC*V*L*W*YTSR NVLQKG*EDHTAPAGR*ELVRREDPGDIPTRHLP HHLRGCDQATTGEKPCGLHGPAFLLLPKSQCHC KPTVFQSQQAHHASPLISAPLPPSPVPRDARCH L*VDLTDCGGPRQAFSGPDPTLASSARGFYL*H* PPRLVTKGQSLPVSQPPPFELVRSSHPTISSFS TGPTFPTQNLLPSTYFPGLPSHEWRRWCPHAIF RHPPR*LLAAAAGEL**CHLPA**CL*QPEQEAA MARREWTI*EESREGGRRKRPWWTQDL*EELLE AFRRGQVPEY*TETLRSQHP*GEPARQAPG*RF SRK*G*ADRAA*RWRAGGEESCSERWEPATSSPA AKSHPRQESNLTRFI*LSSII*LYTTE***VGT PRWRYR*CHGKM*RWMVCWYFKKDKAVWYFSRQ LCKTFVSIRRLKTMEIIFIGGGSIIHEPIFLVES VGKLIQWIK*EAKDRDREVLCLKPKPV*GYCVL DRAELVC*AKRIEANCIYLAASGSHFSLSPPLH FLGNLT*SIVQEQS*PEMPPAAPALESSHLNH*A *RLQAQECNKTPSLHFSAPLEPADPVTLLEVSL SYQDCP*TKVESPTLPKTKSLTQPAEVWMGKQR QN*GT*CIQPAVQQCH*LP*CSERNAHKVCP*EL GSRWPSR*VMSVF*VMKSGSPVALEATCGSFFS HILGF*KWLPSGQCSCIYQSTIAKFSFLACVFL GQFRIGRPILIEHQK*CSVIHLTYTNVLWLLGGQ P*ARHAQGLPWLQIYSL*EFKDHTNGSNQGCES EYTLARLLFRLKQQFCHYQQQPGRLFFVGARSE ERGPCDARAAWSQLCPIQGCLSASLRS*VRQIQK *PIPCPPETQR*LGRLTQENELNQERL*YVLRR V*GRER*IFPGGILESIVILPSPLAHF*TTRVL EEPLSEGSS*LEILGIFSRVSKLSSSPTDTHPSS QIGVAILGGRVVYGTPGCLHISQNYPRTIVPKS RVFTGRQNLFSMPVPQLLSQIPILGSHQLPIPH QTATVPSLSPYCSFKSCSQERNCH*FIHTKV*MI DNRNELPLPTDICF*V*QSRALIPREKVMELEG VSFLGRRRLPEFP*NPVRVRPVVLEGLLHHLRA LFFFFCCCCCFTVSEGI**KCICTCNLHGSISPI VDCIG*CVSWSLDANH**HYLIS*FFQGCFLIS REF*TPL*IQLENKTNL*SHICI*CQPHAFVYL QKFRYASPICPSLIKSCVKICITSPSYV*RNKKQ RFPIALLSSDI**YKVPIFMLKCLYRFINSKCN *LAACLATHFDILAMLPGKGKPQTPYLLQSLWD Q*KKKKIMCLRSGTVNMYI*LCIAHVPTLYRKII LKI*MEGGKGSHEVFLHFYLNEGIPNNSPTDF* HKNSHCKVLKFTISILLGRKGNSDLSYSFFFLF NFIILGFWFLQSYLSAVVLSPIARIGYYKKGYIL KEK*LTLYITN*FKVLPFKLHTESMSYADIDFS VHLFFFIAVD*FDK*MC*ITTFAVHII**TLFR IAW

Sequence NM_015385

AGCGCTGAGTCCCAGAAAAACAGAGCGGGGCCAGCTGCAGCGTGTAGTGCGAGTGGGGCGGACGCGCGCAGCCCGCCCGCCCGGCGACCAGCAAGGAGTT GGCATCCTTTGGAAGAGTTCGTGAAAGCTTTCTGCCCAGAGCTCCTGGACCAATGCATCTTCCCACCACCTTAAACCACTGAGCAGTTCAGAGCCCCAGT TGCAGACGACTTGTCCTGCCACCACCATGAGTTCTGAATGTGATGGTGGTTCCAAAGCTGTGATGAATGGCTTGGCACCTGGCAGCAATGGGCAAGACAA AGACATGGATCTTACAAAAATCTGCACTGGGAAGGGAGCGGTGACTCTCCGGGCCTCGTCTTCCTACAGGGAAACCCCAAGCAGTAGCCCTGCGAGCCCT CAGGAAACCCGGCAACACGAAAGCAAACCAGGTCTGGAGCCAGAGCCTTCTTCAGCAGATGAGTGGAGGCTTTCTTCCAGTGCTGATGCCAATGGAAATG CCCAGCCCTCTTCACTCGCTGCCAAGGGCTACAGAAGTGTGCATCCCAACCTTCCTTCTGACAAGTCCCAGGATGCCACTTCCTCCAGTGCAGCCCAGCC GGAGGTAATAGTTGTCCCTCTCTACCTGGTTAATACTGACAGAGGGCAAGAAGGCACTGCCAGACCTCCAACACCTCTGGGGCCTCTTGGCTGCGTCCCC ACAATCCCAGCGACTGCCTCTGCCGCCTCACCTCTGACCTTCCCGACTCTAGATGATTTCATTCCCCCTCATCTGCAGAGGTGGCCCCACCACAGCCAGC CAGCCCGCGCCTCTGGCTCCTTTGCCCCCATTAGCCAGACGCCACCATCCTTCTCACCACCACCTCCGCTGGTCCCTCCTGCCCCGGAGGACCTCCGCAG AGTCTCGGAGCCTGACCTCACGGGAGCTGTTTCGAGTACCGATTCCAGTCCTCTACTAAATGAAGTTTCTTCTTCCCTTATTGGAACTGATTCCCAAGCC TTTCCATCAGTTAGCAAGCCTTCATCCGCCTATCCCTCCACAACGATTGTCAATCCTACTATTGTGCTCTTGCAACACAATCGAGAACAGCAAAAACGAC TCAGTAGCCTTTCAGATCCTGTCTCAGAAAGAAGAGTGGGAGAGCAGGACTCAGCACCAACCCAGGAAAAACCCACCTCACCTGGCAAGGCTATTGAAAA AAGAGCAAAGGATGACAGTAGGCGGGTGGTGAAGAGCACTCAGGACTTAAGCGATGTTTCCATGGATGAAGTGGGCATCCCACTCCGGAACACTGAGAGA TCAAAAGACTGGTACAAGACTATGTTTAAACAGATCCACAAACTGAACAGAGATGATGATTCAGATCTGTACTCTCCCAGATACTCATTTTCTGAAGACA CAAAATCTCCCCTTTCTGTGCCTCGCTCAAAAAGTGAGATGAGCTACATTGATGGTGAGAAGGTAGTCAAGAGGTCGGCCACACTACCCCTCCCAGCCCG CTCTTCCTCACTGAAGTCAAGCTCAGAAAGAAATGACTGGGAACCCCCAGATAAGAAAGTAGACACAAGAAAATATCGTGCAGAGCCCAAGAGCATTTAC GAATATCAGCCTGGCAAGTCTTCCGTTCTGACCAACGAAAAGATGAGCTCAGCCATCAGCCCTACTCCGGAAATTTCTTCAGAGACTCCTGGATATATAT ATTCTTCCAACTTCCATGCAGTGAAGAGGGAATCAGACGGGGCTCCTGGGGATCTCACTAGCTTGGAGAATGAGAGACAAATTTATAAAAGTGTCTTGGA AGGTGGTGACATCCCTCTTCAGGGCCTGAGTGGGCTCAAGCGACCATCCAGCTCTGCTTCCACTAAAGATTCAGAATCGCCAAGACATTTTATACCAGCT GATTACTTGGAATCCACGGAAGAATTTATTCGAAGACGTCATGATGATAAAGAGATGAGACCTGCCAGAGCCAAATTTGACTTTAAAGCTCAGACACTAA AGGAGCTTCCTCTGCAGAAGGGAGATATTGTTTACATTTATAAGCAAATTGATCAGAACTGGTATGAAGGAGAACACCACGGCCGGGTGGGAATCTTCCC ACGCACCTACATCGAGCTTCTTCCTCCTGCTGAGAAGGCACAGCCCAAAAAGTTGACACCAGTGCAGGTTTTGGAATATGGAGAAGCTATTGCTAAGTTT AACTTTAATGGTGATACACAAGTAGAAATGTCCTTCAGAAAGGGTGAGAGGATCACACTGCTCCGGCAGGTAGATGAGAACTGGTACGAAGGGAGGATCC CGGGGACATCCCGACAAGGCATCTTCCCCATCACCTACGTGGATGTGATCAAGCGACCACTGGTGAAAAACCCTGTGGATTACATGGACCTGCCTTTCTC CTCCTCCCCAAGTCGCAGTGCCACTGCAAGCCCACAGCAACCTCAAGCCCAGCAGCGAAGAGTCACCCCCGACAGGAGTCAAACCTCACAAGATTTATTT AGCTATCAAGCATTATATAGCTATATACCACAGAATGATGATGAGTTGGAACTCCGCGATGGAGATATCGTTGATGTCATGGAAAAATGTGACGATGGAT GGTTTGTTGGTACTTCAAGAAGGACAAAGCAGTTTGGTACTTTTCCAGGCAACTATGTAAAACCTTTGTATCTATAAGAAGACTGAAAACCATGGAGATT ATTTTTATTGGAGGAGGAAGCATCATTCATGAACCGATCTTTTTAGTTGAGTCAGTAGGAAAATTAATACAGTGGATAAAGTAAGAAGCAAAAGACAGGG ACAGAGAAGTGTTGTGTTTAAAACCCAAGCCTGTCTAAGGTTACTGTGTATTAGACAGGGCCGAACTAGTGTGCTGAGCAAAAAGAATTGAAGCAAATTG TATTTACTTAGCCGCTTCTGGGAGCCACTTCAGCCTTTCCCCTCCCCTCCACTTCTTGGGTAATCTGACCTGAAGCATAGTCCAGGAGCAGAGTTAGCCA GAAATGCCTCCTGCTGCCCCAGCCTTAGAGAGCTCCCATCTCAATCATTGAGCCTGAAGGCTTCAAGCCCAAGAATGCAACAAGACCCCCAGCCTACATT TCTCAGCTCCCCTGGAGCCAGCTGATCCTGTAACGCTGCTGGAGGTCAGTCTGAGCTACCAAGACTGTCCCTAGACAAAGGTGGAGTCCCCCACACTGCC CAAGACCAAATCCCTCACTCAACCTGCTGAGGTGTGGATGGGGAAACAGAGGCAAAACTGAGGCACCTGATGCATTCAGCCTGCTGTGCAGCAGTGCCAT TGACTGCCCTGATGTTCAGAGAGAAACGCACACAAGGTTTGCCCATGAGAATTGGGGAGCAGATGGCCAAGCAGATAGGTTATGTCTGTTTTCTGAGTGA TGAAGTCAGGAAGCCCTGTGGCTCTGGAGGCCACTTGTGGTTCATTCTTTTCCCATATCCTTGGCTTTTAGAAATGGTTACCTTCAGGACAGTGCAGCTG CATTTATCAGAGCACTATTGCTAAGTTTTCTTTTCTGGCTTGTGTTTTTCTGGGACAGTTTAGAATTGGGAGGCCTATTCTCATAGAACACCAAAAATGA TGTTCAGTGATTCATTTAACATACACCAATGTACTCTGGCTGCTGGGGGGACAACCATAAGCAAGACATGCCCAGGGTTTGCCGTGGCTCCAGATCTACT CCCTGTAGGAGTTCAAGGATCACACAAACGGTAGTAACCAGGGTTGTGAATCTGAGTACACCCTGGCAAGGCTTCTCTTCAGACTGAAGCAGCAATTCTG CCACTACCAGCAGCAACCAGGACGTCTGTTCTTTGTGGGGGCCAGATCAGAAGAGAGAGGCCCCTGTGACGCCCGGGCTGCTTGGTCACAACTCTGTCCA ATTCAAGGATGTTTATCGGCCTCTCTTAGATCCTGAGTGAGACAAATACAGAAATGACCCATTCCCTGCCCACCAGAAACTCAGAGGTGATTGGGGAGAC TGACACAGGAAAATGAACTTAATCAAGAGAGACTGTGATATGTGCTAAGAAGGGTGTGAGGGAGGGAGAGATGAATTTTCCCTGGAGGGATCCTAGAAAG CATTGTCATATTGCCATCTCCATTAGCTCACTTTTAAACAACTAGGGTGCTGGAAGAACCTTTGTCTGAGGGTAGTTCATAGCTGGAAATACTTGGAATA TTTTCCAGAGTCTCTAAACTCTCATCTTCCCCCACAGATACACATCCAAGCTCACAAATAGGAGTAGCAATTCTAGGTGGTAGGGTTGTGTACGGAACCC CTGGCTGTCTGCATATATCTCAGAATTACCCCAGGACCATTGTCCCAAAGTCTAGAGTCTTTACAGGTAGGCAAAATTTGTTTTCAATGCCTGTGCCTCA GCTGCTGTCACAAATACCCATCTTAGGATCCCATCAGCTTCCCATCCCCCACCAGACAGCCACAGTACCCTCACTTTCTCCCTATTGTTCTTTCAAATCC TGTTCTCAGGAAAGAAACTGCCACTAATTCATTCACACTAAGGTGTAAATGATTGATAATAGGAATGAGTTACCTCTTCCCACAGACATTTGTTTTTAAG TATGACAGAGCAGGGCCTTAATCCCAAGGGAAAAGGTTATGGAACTGGAGGGGGTGAGCTTTCTGGGTAGAAGGAGACTTCCTGAATTTCCTTAAAACCC AGTAAGAGTAAGACCTGTTGTTTTGGAAGGTCTGCTCCACCATCTAAGAGCACTGTTTTTTTTTTTTTGTTGTTGTTGTTGTTTTACGGTCTCTGAGGGA ATATAGTAAAAATGCATATGCACGTGCAATTTGCACGGCAGCATTTCACCGATTGTGGACTGTATTGGCTAATGTGTTTCCTGGTCTTTAGATGCAAACC ATTAATAACACTATCTTATCTCATAGTTTTTTCAGGGGTGCTTCTTGATTAGTAGGGAATTTTGAACACCTCTTTAAATACAGCTAGAAAATAAAACCAA TTTGTAAAGCCACATTTGCATATGATGCCAGCCTCACGCATTTGTATATCTCCAGAAATTCAGGTATGCCTCACCAATTTGCCCGTCTTTAATAAAATCT TGTGTTAAAATTTGCATCACGTCGCCTTCCTATGTATGACGAAACAAGAAACAGAGATTTCCAATTGCTCTTTTGTCTTCAGACATTTAGTAATATAAAG TACCTATTTTTATGCTGAAATGTTTATACAGGTTTATTAATAGCAAGTGCAACTAACTGGCGGCATGCCTTGCAACACATTTTGATATATTAGCCATGCT TCCGGGTAAAGGCAAGCCCCAAACTCCTTATCTTTTGCAGTCTCTCTGGGATCAGTAAAAGAAAAAAAAAATAATGTGCTTAAGAAGTGGGACTGTAAAT ATGTATATTTAACTTTGTATAGCCCATGTACCTACCTTGTATAGAAAAATAATTTTAAAAATTTGAATGGAAGGGGGTAAAGGAAGTCATGAAGTTTTTT TGCATTTTTATTTAAATGAAGGAATTCCAAATAACTCACCTACAGATTTTTAGCACAAAAATAGCCATTGTAAAGTGTTAAAATTTACGATAAGTATTCT ATTGGGGAGGAAAGGTAACTCTGATCTCAGTTACAGTTTTTTTTTCCTTTTTAATTTCATTATTTTGGGTTTTTGGTTTTTGCAGTCCTATTTATCTGCA GTCGTATTAAGTCCTATTGCTAGAATAGGTTACTACAAAAAAGGTTATATTCTGAAAGAAAAATAACTGACATTATATATAACCAATTAATTTAAAGTAT TGCCATTTAAATTACACACTGAGAGCATGTCCTATGCAGACATAGATTTTTCTGTTCATTTATTTTTCTTCATTGCAGTGGATTGATTTGATAAATAGAT GTGTTGAATTACTACATTTGCTGTACATATTATTTAATAAACTTTATTCAGAATTGCGTGGCA

refseq_SORBS1.F1 (forward primer)
refseq_SORBS1.R1 (reverse primer)
Alternative acceptor

Frame 0

SAESQKNRAGPAAACSASGADARSPPARRPARS WHPLEEFVKAFCPELLDQCIFPPP*TTEQFRAPV ADDLSCHHHEF*M*WWFQSCDEWLGTWQQWARQ RHGSYKNLHWEGSGDSPGLVFLQGNPKQ*PCEP SGNPATRKQTRSGARAFFSR*VEAFFQC*CQWKC PALFTRCQGLQKCASQPSF*QVPGCHFLQCSPA GGNSCPSLPG*Y*QRARRHCQTSNTSGASWLRP HNPSDCLCRLTSDLPDSR*FHSPSSAEVAPPQPA SPRLWLLCPH*PDATILLTTTSAGPSCPGGPPQ SLGA*PHGSCFEYRFQSSTK*SFFFPYWN*FPS LSIS*QAFIRLSLHNDCQSYYCALATQSRTAKTT Q*PFRSCLRKKSGRAGLSTNPGKTHLTWQGY*K KSKG*Q*AGGEEHSGLKRCFHG*SGHPTPEH*E IKRLVQDYV*TDPQTEQR**FRSVLSQILIF*RH KISPFCASLKK*DELH*W*EGSQEVGHTTPPSP LFLTEVKLRKK*LGTPR*ESRHKKISCRAQEHL RISAWQVFRSDQRKDELSHQPYSGNFFRDSWIYI FFQLPCSEEGIRRGSWGSH*LGE*ETNL*KCLG RW*HPSSGPEWAQATIQLCFH*RFRIAKTFYTS *LLGIHGRIYSKTS***RDETCQSQI*L*SSDTK GASSAEGRYCLHL*AN*SELV*RRTPRPGGNLP THLHRASSSC*EGTAQKVDTSAGFGIWRSYC*V *L*W*YTSRNVLQKG*EDHTAPAGR*ELVRREDP GDIPTRHLPHHLRGCDQATTGEKPCGLHGPAFL LLPKSQCHCKPTATSSPAAKSHPRQESNLTRFI *LSSII*LYTTE***VGTPRWRYR*CHGKM*RWM VCWYFKKDKAVWYFSRQLCKTFVSIRRLKTMEI IFIGGGSIIHEPIFLVESVGKLIQWIK*EAKDR DREVLCLKPKPV*GYCVLDRAELVC*AKRIEANC IYLAASGSHFSLSPPLHFLGNLT*SIVQEQS*P EMPPAAPALESSHLNH*A*RLQAQECNKTPSLH FSAPLEPADPVTLLEVSLSYQDCP*TKVESPTLP KTKSLTQPAEVWMGKQRQN*GT*CIQPAVQQCH *LP*CSERNAHKVCP*ELGSRWPSR*VMSVF*V MKSGSPVALEATCGSFFSHILGF*KWLPSGQCSC IYQSTIAKFSFLACVFLGQFRIGRPILIEHQK* CSVIHLTYTNVLWLLGGQP*ARHAQGLPWLQIY SL*EFKDHTNGSNQGCESEYTLARLLFRLKQQFC HYQQQPGRLFFVGARSEERGPCDARAAWSQLCP IQGCLSASLRS*VRQIQK*PIPCPPETQR*LGR LTQENELNQERL*YVLRRV*GRER*IFPGGILES IVILPSPLAHF*TTRVLEEPLSEGSS*LEILGI FSRVSKLSSSPTDTHPSSQIGVAILGGRVVYGT PGCLHISQNYPRTIVPKSRVFTGRQNLFSMPVPQ LLSQIPILGSHQLPIPHQTATVPSLSPYCSFKS CSQERNCH*FIHTKV*MIDNRNELPLPTDICF* V*QSRALIPREKVMELEGVSFLGRRRLPEFP*NP VRVRPVVLEGLLHHLRALFFFFCCCCCFTVSEG I**KCICTCNLHGSISPIVDCIG*CVSWSLDAN H**HYLIS*FFQGCFLISREF*TPL*IQLENKTN L*SHICI*CQPHAFVYLQKFRYASPICPSLIKS CVKICITSPSYV*RNKKQRFPIALLSSDI**YK VPIFMLKCLYRFINSKCN*LAACLATHFDILAML PGKGKPQTPYLLQSLWDQ*KKKKIMCLRSGTVN MYI*LCIAHVPTLYRKIILKI*MEGGKGSHEVF LHFYLNEGIPNNSPTDF*HKNSHCKVLKFTISIL LGRKGNSDLSYSFFFLFNFIILGFWFLQSYLSA VVLSPIARIGYYKKGYILKEK*LTLYITN*FKV LPFKLHTESMSYADIDFSVHLFFFIAVD*FDK*M C*ITTFAVHII**TLFRIAW

Frame 1

ALSPRKTERGQLQRVVRVGRTRAARPPGDQQGV GILWKSS*KLSAQSSWTNASSHHLKPLSSSEPQ LQTTCPATTMSSECDGGSKAVMNGLAPGSNGQDK DMDLTKICTGKGAVTLRASSSYRETPSSSPASP QETRQHESKPGLEPEPSSADEWRLSSSADANGN AQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQP EVIVVPLYLVNTDRGQEGTARPPTPLGPLGCVP TIPATASAASPLTFPTLDDFIPPHLQRWPHHSQ PARASGSFAPISQTPPSFSPPPPLVPPAPEDLRR VSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQA FPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKR LSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEK RAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTER SKDWYKTMFKQIHKLNRDDDSDLYSPRYSFSED TKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPAR SSSLKSSSERNDWEPPDKKVDTRKYRAEPKSIY EYQPGKSSVLTNEKMSSAISPTPEISSETPGYI YSSNFHAVKRESDGAPGDLTSLENERQIYKSVLE GGDIPLQGLSGLKRPSSSASTKDSESPRHFIPA DYLESTEEFIRRRHDDKEMRPARAKFDFKAQTL KELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFP RTYIELLPPAEKAQPKKLTPVQVLEYGEAIAKF NFNGDTQVEMSFRKGERITLLRQVDENWYEGRI PGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFS SSPSRSATASPQQPQAQQRRVTPDRSQTSQDLF SYQALYSYIPQNDDELELRDGDIVDVMEKCDDG WFVGTSRRTKQFGTFPGNYVKPLYL*ED*KPWRL FLLEEEASFMNRSF*LSQ*EN*YSG*SKKQKTG TEKCCV*NPSLSKVTVY*TGPN*CAEQKELKQI VFT*PLLGATSAFPLPSTSWVI*PEA*SRSRVSQ KCLLLPQP*RAPISIIEPEGFKPKNATRPPAYI SQLPWSQLIL*RCWRSV*ATKTVPRQRWSPPHC PRPNPSLNLLRCGWGNRGKTEAPDAFSLLCSSAI DCPDVQRETHTRFAHENWGADGQADRLCLFSE* *SQEALWLWRPLVVHSFPISLAFRNGYLQDSAA AFIRALLLSFLFWLVFFWDSLELGGLFS*NTKND VQ*FI*HTPMYSGCWGDNHKQDMPRVCRGSRST PCRSSRITQTVVTRVVNLSTPWQGFSSD*SSNS ATTSSNQDVCSLWGPDQKREAPVTPGLLGHNSVQ FKDVYRPLLDPE*DKYRNDPFPAHQKLRGDWGD *HRKMNLIKRDCDMC*EGCEGGRDEFSLEGS*K ALSYCHLH*LTFKQLGCWKNLCLRVVHSWKYLEY FPESLNSHLPPQIHIQAHK*E*QF*VVGLCTEP LAVCIYLRITPGPLSQSLESLQVGKICFQCLCL SCCHKYPS*DPISFPSPTRQPQYPHFLPIVLSNP VLRKETATNSFTLRCK*LIIGMSYLFPQTFVFK YDRAGP*SQGKRLWNWRG*AFWVEGDFLNFLKT Q*E*DLLFWKVCSTI*EHCFFFFVVVVVLRSLRE YSKNAYARAICTAAFHRLWTVLANVFPGL*MQT INNTILSHSFFRGAS*LVGNFEHLFKYS*KIKP ICKATFAYDASLTHLYISRNSGMPHQFARL**NL VLKFASRRLPMYDETRNRDFQLLFCLQTFSNIK YLFLC*NVYTGLLIASATNWRHALQHILIY*PC FRVKASPKLLIFCSLSGISKRKKK*CA*EVGL*I CIFNFV*PMYLPCIEK*F*KFEWKGVKEVMKFF CIFI*MKEFQITHLQIFSTKIAIVKC*NLR*VF YWGGKVTLISVTVFFSFLISLFWVFGFCSPIYLQ SY*VLLLE*VTTKKVIF*KKNN*HYI*PINLKY CHLNYTLRACPMQT*IFLFIYFSSLQWIDLINR CVELLHLLYILFNKLYSELRG

Frame 2

R*VPEKQSGASCSV*CEWGGRAQPARPATSKEL ASFGRVRESFLPRAPGPMHLPTTLNH*AVQSPS CRRLVLPPP*VLNVMVVPKL**MAWHLAAMGKT KTWILQKSALGRER*LSGPRLPTGKPQAVALRAL RKPGNTKANQVWSQSLLQQMSGGFLPVLMPMEM PSPLHSLPRATEVCIPTFLLTSPRMPLPPVQPS RR**LSLSTWLILTEGKKALPDLQHLWGLLAASP QSQRLPLPPHL*PSRL*MISFPLICRGGPTTAS QPAPLAPLPPLARRHHPSHHHLRWSLLPRRTSA ESRSLTSRELFRVPIPVLY*MKFLLPLLELIPKP FHQLASLHPPIPPQRLSILLLCSCNTIENSKND SVAFQILSQKEEWESRTQHQPRKNPPHLARLLK KEQRMTVGGW*RALRT*AMFPWMKWASHSGTLRD QKTGTRLCLNRSTN*TEMMIQICTLPDTHFLKT QNLPFLCLAQKVR*ATLMVRR*SRGRPHYPSQP ALPH*SQAQKEMTGNPQIRK*TQENIVQSPRAFT NISLASLPF*PTKR*AQPSALLRKFLQRLLDIY ILPTSMQ*RGNQTGLLGISLAWRMRDKFIKVSW KVVTSLFRA*VGSSDHPALLPLKIQNRQDILYQL ITWNPRKNLFEDVMMIKR*DLPEPNLTLKLRH* RSFLCRREILFTFISKLIRTGMKENTTAGWESS HAPTSSFFLLLRRHSPKS*HQCRFWNMEKLLLSL TLMVIHK*KCPSERVRGSHCSGR*MRTGTKGGS RGHPDKASSPSPTWM*SSDHW*KTLWITWTCLS PPPQVAVPLQAHSNLKPSSEESPPTGVKPHKIYL AIKHYIAIYHRMMMSWNSAMEISLMSWKNVTMD GLLVLQEGQSSLVLFQATM*NLCIYKKTENHGD YFYWRRKHHS*TDLFS*VSRKINTVDKVRSKRQG QRSVVFKTQACLRLLCIRQGRTSVLSKKN*SKL YLLSRFWEPLQPFPSPPLLG*SDLKHSPGAELA RNASCCPSLRELPSQSLSLKASSPRMQQDPQPTF LSSPGAS*SCNAAGGQSELPRLSLDKGGVPHTA QDQIPHSTC*GVDGETEAKLRHLMHSACCAAVP LTALMFREKRTQGLPMRIGEQMAKQIGYVCFLSD EVRKPCGSGGHLWFILFPYPWLLEMVTFRTVQL HLSEHYC*VFFSGLCFSGTV*NWEAYSHRTPKM MFSDSFNIHQCTLAAGGTTISKTCPGFAVAPDLL PVGVQGSHKR**PGL*I*VHPGKASLQTEAAIL PLPAATRTSVLCGGQIRRERPL*RPGCLVTTLS NSRMFIGLS*ILSETNTEMTHSLPTRNSEVIGET DTGK*T*SRETVICAKKGVREGEMNFPWRDPRK HCHIAISISSLLNN*GAGRTFV*G*FIAGNTWN IFQSL*TLIFPHRYTSKLTNRSSNSRW*GCVRNP WLSAYISELPQDHCPKV*SLYR*AKFVFNACAS AAVTNTHLRIPSASHPPPDSHSTLTFSLLFFQI LFSGKKLPLIHSH*GVND***E*VTSSHRHLFLS MTEQGLNPKGKGYGTGGGELSG*KETS*ISLKP SKSKTCCFGRSAPPSKSTVFFFLLLLLFYGL*G NIVKMHMHVQFARQHFTDCGLYWLMCFLVFRCKP LITLSYLIVFSGVLLD**GILNTSLNTARK*NQ FVKPHLHMMPASRICISPEIQVCLTNLPVFNKI LC*NLHHVAFLCMTKQETEISNCSFVFRHLVI*S TYFYAEMFIQVY**QVQLTGGMPCNTF*YISHA SG*RQAPNSLSFAVSLGSVKEKKNNVLKKWDCK YVYLTLYSPCTYLV*KNNFKNLNGRG*RKS*SFF AFLFK*RNSK*LTYRFLAQK*PL*SVKIYDKYS IGEER*L*SQLQFFFPF*FHYFGFLVFAVLFIC SRIKSYC*NRLLQKRLYSERKITDIIYNQLI*SI AI*ITH*EHVLCRHRFFCSFIFLHCSGLI**ID VLNYYICCTYYLINFIQNCVA

Sequence NM_001034955

AGCAGTTCAGAGCCCCAGTTGCAGACGACTTGTCCTGCCACCACCATGAGTTCTGAATGTGATGGTGGTTCCAAAGCTGTGATGAATGGCTTGGCACCTG GCAGCAATGGGCAAGACAAAGCAACTGCCGACCCTTTACGCGCACGCTCTATTTCTGCTGTTAAAATCATTCCTGTGAAGACAGTGAAAAACGCCTCAGG CCTAGTTCTCCCTACAGACATGGATCTTACAAAAATCTGCACTGGGAAGGGAGCGGTGACTCTCCGGGCCTCGTCTTCCTACAGGGAAACCCCAAGCAGT AGCCCTGCGAGCCCTCAGGAAACCCGGCAACACGAAAGCAAACCAGGTCTGGAGCCAGAGCCTTCTTCAGCAGATGAGTGGAGGCTTTCTTCCAGTGCTG ATGCCAATGGAAATGCCCAGCCCTCTTCACTCGCTGCCAAGGGCTACAGAAGTGTGCATCCCAACCTTCCTTCTGACAAGTCCCAGGATGCCACTTCCTC CAGTGCAGCCCAGCCGGAGGTAATAGTTGTCCCTCTCTACCTGGTTAATACTGACAGAGGGCAAGAAGGCACTGCCAGACCTCCAACACCTCTGGGGCCT CTTGGCTGCGTCCCCACAATCCCAGCGACTGCCTCTGCCGCCTCACCTCTGACCTTCCCGACTCTAGATGATTTCATTCCCCCTCATCTGCAGAGGTGGC CCCACCACAGCCAGCCAGCCCGCGCCTCTGGCTCCTTTGCCCCCATTAGCCAGACGCCACCATCCTTCTCACCACCACCTCCGCTGGTCCCTCCTGCCCC GGAGGACCTCCGCAGAGTCTCGGAGCCTGACCTCACGGGAGCTGTTTCGAGTACCGATTCCAGTCCTCTACTAAATGAAGTTTCTTCTTCCCTTATTGGA ACTGATTCCCAAGCCTTTCCATCAGTTAGCAAGCCTTCATCCGCCTATCCCTCCACAACGATTGTCAATCCTACTATTGTGCTCTTGCAACACAATCGAG AACAGCAAAAACGACTCAGTAGCCTTTCAGATCCTGTCTCAGAAAGAAGAGTGGGAGAGCAGGACTCAGCACCAACCCAGGAAAAACCCACCTCACCTGG CAAGGCTATTGAAAAAAGAGCAAAGGATGACAGTAGGCGGGTGGTGAAGAGCACTCAGGACTTAAGCGATGTTTCCATGGATGAAGTGGGCATCCCACTC CGGAACACTGAGAGATCAAAAGACTGGTACAAGACTATGTTTAAACAGATCCACAAACTGAACAGAGACACTCCTGAAGAAAACCCTTATTTCCCTACGT ACAAATTCCCTGAACTTCCTGAAATCCAGCAAACTTCCGAAGAGACAAAGTCTTGCTCTGTCATGTCACCCAGGCTGGAGTGCAGTGGTACAGTCATAGC TCACTGCAGCCTCAAACTCCTAGACTCAAGCAATCCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTGCAGATGATGATTCAGATCTGTACTCTCCCAGA TACTCATTTTCTGAAGACACAAAATCTCCCCTTTCTGTGCCTCGCTCAAAAAGTGAGATGAGCTACATTGATGGTGAGAAGGTAGTCAAGAGGTCGGCCA CACTACCCCTCCCAGCCCGCTCTTCCTCACTGAAGTCAAGCTCAGAAAGAAATGACTGGGAACCCCCAGATAAGAAAGTAGACACAAGAAAATATCGTGC AGAGCCCAAGAGCATTTACGAATATCAGCCTGGCAAGTCTTCCGTTCTGACCAACGAAAAGATGAGTCGGGATATAAGCCCAGAAGAGATAGATTTAAAG AATGAACCTTGGTATAAATTCTTTTCGGAATTGGAGTTTGGGAAACCGCCTCCCAAAAAGATATGGGATTATACTCCTGGAGACTGCTCTATCCTTCCTA GAGAGGATAGAAAGACTAATCTAGACAAAGATCTCAGCCTCTGCCAGACAGAGTTAGAGGCAGATTTAGAAAAAATGGAGACGCTTAATAAAGCACCCAG TGCAAACGTGCCACAGAGCTCAGCCATCAGCCCTACTCCGGAAATTTCTTCAGAGACTCCTGGATATATATATTCTTCCAACTTCCATGCAGTGAAGAGG GAATCAGACGGGGCTCCTGGGGATCTCACTAGCTTGGAGAATGAGAGACAAATTTATAAAAGTGTCTTGGAAGGTGGTGACATCCCTCTTCAGGGCCTGA GTGGGCTCAAGCGACCATCCAGCTCTGCTTCCACTAAAGATTCAGAATCGCCAAGACATTTTATACCAGCTGATTACTTGGAATCCACGGAAGAATTTAT TCGAAGACGTCATGATGATAAAGAGAAACTTTTAGCGGACCAGAGACGACTTAAACGCGAGCAAGAAGAGGCTGATATTGCAGCTCGACGCCACACAGGC GTCATTCCGACGCACCATCAGTTTATCACTAATGAGCGCTTTGGGGACCTCCTCAATATAGACGATACTGCAAAAAGGAAATCTGGGTCAGAGATGAGAC CTGCCAGAGCCAAATTTGACTTTAAAGCTCAGACACTAAAGGAGCTTCCTCTGCAGAAGGGAGATATTGTTTACATTTATAAGCAAATTGATCAGAACTG GTATGAAGGAGAACACCACGGCCGGGTGGGAATCTTCCCACGCACCTACATCGAGCTTCTTCCTCCTGCTGAGAAGGCACAGCCCAAAAAGTTGACACCA GTGCAGGTTTTGGAATATGGAGAAGCTATTGCTAAGTTTAACTTTAATGGTGATACACAAGTAGAAATGTCCTTCAGAAAGGGTGAGAGGATCACACTGC TCCGGCAGGTAGATGAGAACTGGTACGAAGGGAGGATCCCGGGGACATCCCGACAAGGCATCTTCCCCATCACCTACGTGGATGTGATCAAGCGACCACT GGTGAAAAACCCTGTGGATTACATGGACCTGCCTTTCTCCTCCTCCCCAAGTCGCAGTGCCACTGCAAGCCCACAGCCATGGCGCGAAGAGAGTGGACAA TATGAGAGGAAAGCAGAGAGGGGGGCAGGCGAAAGAGGCCCTGGTGGACCCAAGATCTCTAAGAAGAGCTGCTTGAAGCCTTCAGACGTGGTCAGGTGCC TGAGTACTGAACAGAGACTCTCAGATCTCAACACCCCTGAGGAGAGCCGGCCCGGCAAGCCCCTGGGTAGCGCTTTTCCAGGAAGTGAGGCTGAGCAGAC AGAGCGGCATAGAGGTGGCGAGCAGGCGGGGAGGAAAGCTGCTCGGAGAGGTGGGAGCCAGCAACCTCAAGCCCAGCAGCGAAGAGTCACCCCCGACAGG AGTCAAACCTCACAAGATTTATTTAGCTATCAAGCATTATATAGCTATATACCACAGAATGATGATGAGTTGGAACTCCGCGATGGAGATATCGTTGATG TCATGGAAAAATGTGACGATGGATGGTTTGTTGGTACTTCAAGAAGGACAAAGCAGTTTGGTACTTTTCCAGGCAACTATGTAAAACCTTTGTATCTATA AGAAGACTGAAAACCATGGAGATTATTTTTATTGGAGGAGGAAGCATCATTCATGAACCGATCTTTTTAGTTGAGTCAGTAGGAAAATTAATACAGTGGA TAAAGTAAGAAGCAAAAGACAGGGACAGAGAAGTGTTGTGTTTAAAACCCAAGCCTGTCTAAGGTTACTGTGTATTAGACAGGGCCGAACTAGTGTGCTG AGCAAAAAGAATTGAAGCAAATTGTATTTACTTAGCCGCTTCTGGGAGCCACTTCAGCCTTTCCCCTCCCCTCCACTTCTTGGGTAATCTGACCTGAAGC ATAGTCCAGGAGCAGAGTTAGCCAGAAATGCCTCCTGCTGCCCCAGCCTTAGAGAGCTCCCATCTCAATCATTGAGCCTGAAGGCTTCAAGCCCAAGAAT GCAACAAGACCCCCAGCCTACATTTCTCAGCTCCCCTGGAGCCAGCTGATCCTGTAACGCTGCTGGAGGTCAGTCTGAGCTACCAAGACTGTCCCTAGAC AAAGGTGGAGTCCCCCACACTGCCCAAGACCAAATCCCTCACTCAACCTGCTGAGGTGTGGATGGGGAAACAGAGGCAAAACTGAGGCACCTGATGCATT CAGCCTGCTGTGCAGCAGTGCCATTGACTGCCCTGATGTTCAGAGAGAAACGCACACAAGGTTTGCCCATGAGAATTGGGGAGCAGATGGCCAAGCAGAT AGGTTATGTCTGTTTTCTGAGTGATGAAGTCAGGAAGCCCTGTGGCTCTGGAGGCCACTTGTGGTTCATTCTTTTCCCATATCCTTGGCTTTTAGAAATG GTTACCTTCAGGACAGTGCAGCTGCATTTATCAGAGCACTATTGCTAAGTTTTCTTTTCTGGCTTGTGTTTTTCTGGGACAGTTTAGAATTGGGAGGCCT ATTCTCATAGAACACCAAAAATGATGTTCAGTGATTCATTTAACATACACCAATGTACTCTGGCTGCTGGGGGGACAACCATAAGCAAGACATGCCCAGG GTTTGCCGTGGCTCCAGATCTACTCCCTGTAGGAGTTCAAGGATCACACAAACGGTAGTAACCAGGGTTGTGAATCTGAGTACACCCTGGCAAGGCTTCT CTTCAGACTGAAGCAGCAATTCTGCCACTACCAGCAGCAACCAGGACGTCTGTTCTTTGTGGGGGCCAGATCAGAAGAGAGAGGCCCCTGTGACGCCCGG GCTGCTTGGTCACAACTCTGTCCAATTCAAGGATGTTTATCGGCCTCTCTTAGATCCTGAGTGAGACAAATACAGAAATGACCCATTCCCTGCCCACCAG AAACTCAGAGGTGATTGGGGAGACTGACACAGGAAAATGAACTTAATCAAGAGAGACTGTGATATGTGCTAAGAAGGGTGTGAGGGAGGGAGAGATGAAT TTTCCCTGGAGGGATCCTAGAAAGCATTGTCATATTGCCATCTCCATTAGCTCACTTTTAAACAACTAGGGTGCTGGAAGAACCTTTGTCTGAGGGTAGT TCATAGCTGGAAATACTTGGAATATTTTCCAGAGTCTCTAAACTCTCATCTTCCCCCACAGATACACATCCAAGCTCACAAATAGGAGTAGCAATTCTAG GTGGTAGGGTTGTGTACGGAACCCCTGGCTGTCTGCATATATCTCAGAATTACCCCAGGACCATTGTCCCAAAGTCTAGAGTCTTTACAGGTAGGCAAAA TTTGTTTTCAATGCCTGTGCCTCAGCTGCTGTCACAAATACCCATCTTAGGATCCCATCAGCTTCCCATCCCCCACCAGACAGCCACAGTACCCTCACTT TCTCCCTATTGTTCTTTCAAATCCTGTTCTCAGGAAAGAAACTGCCACTAATTCATTCACACTAAGGTGTAAATGATTGATAATAGGAATGAGTTACCTC TTCCCACAGACATTTGTTTTTAAGTATGACAGAGCAGGGCCTTAATCCCAAGGGAAAAGGTTATGGAACTGGAGGGGGTGAGCTTTCTGGGTAGAAGGAG ACTTCCTGAATTTCCTTAAAACCCAGTAAGAGTAAGACCTGTTGTTTTGGAAGGTCTGCTCCACCATCTAAGAGCACTGTTTTTTTTTTTTTGTTGTTGT TGTTGTTTTACGGTCTCTGAGGGAATATAGTAAAAATGCATATGCACGTGCAATTTGCACGGCAGCATTTCACCGATTGTGGACTGTATTGGCTAATGTG TTTCCTGGTCTTTAGATGCAAACCATTAATAACACTATCTTATCTCATAGTTTTTTCAGGGGTGCTTCTTGATTAGTAGGGAATTTTGAACACCTCTTTA AATACAGCTAGAAAATAAAACCAATTTGTAAAGCCACATTTGCATATGATGCCAGCCTCACGCATTTGTATATCTCCAGAAATTCAGGTATGCCTCACCA ATTTGCCCGTCTTTAATAAAATCTTGTGTTAAAATTTGCATCACGTCGCCTTCCTATGTATGACGAAACAAGAAACAGAGATTTCCAATTGCTCTTTTGT CTTCAGACATTTAGTAATATAAAGTACCTATTTTTATGCTGAAATGTTTATACAGGTTTATTAATAGCAAGTGCAACTAACTGGCGGCATGCCTTGCAAC ACATTTTGATATATTAGCCATGCTTCCGGGTAAAGGCAAGCCCCAAACTCCTTATCTTTTGCAGTCTCTCTGGGATCAGTAAAAGAAAAAAAAAATAATG TGCTTAAGAAGTGGGACTGTAAATATGTATATTTAACTTTGTATAGCCCATGTACCTACCTTGTATAGAAAAATAATTTTAAAAATTTGAATGGAAGGGG GTAAAGGAAGTCATGAAGTTTTTTTGCATTTTTATTTAAATGAAGGAATTCCAAATAACTCACCTACAGATTTTTAGCACAAAAATAGCCATTGTAAAGT GTTAAAATTTACGATAAGTATTCTATTGGGGAGGAAAGGTAACTCTGATCTCAGTTACAGTTTTTTTTTCCTTTTTAATTTCATTATTTTGGGTTTTTGG TTTTTGCAGTCCTATTTATCTGCAGTCGTATTAAGTCCTATTGCTAGAATAGGTTACTACAAAAAAGGTTATATTCTGAAAGAAAAATAACTGACATTAT ATATAACCAATTAATTTAAAGTATTGCCATTTAAATTACACACTGAGAGCATGTCCTATGCAGACATAGATTTTTCTGTTCATTTATTTTTCTTCATTGC AGTGGATTGATTTGATAAATAGATGTGTTGAATTACTACATTTGCTGTACATATTATTTAATAAACTTTATTCAGAATTGCGTGGCA

refseq_SORBS1.F1 (forward primer)
refseq_SORBS1.R1 (reverse primer)
Alternative acceptor

Frame 0

SSSEPQLQTTCPATTMSSECDGGSKAVMNGLAP GSNGQDKATADPLRARSISAVKIIPVKTVKNASG LVLPTDMDLTKICTGKGAVTLRASSSYRETPSS SPASPQETRQHESKPGLEPEPSSADEWRLSSSA DANGNAQPSSLAAKGYRSVHPNLPSDKSQDATSS SAAQPEVIVVPLYLVNTDRGQEGTARPPTPLGP LGCVPTIPATASAASPLTFPTLDDFIPPHLQRW PHHSQPARASGSFAPISQTPPSFSPPPPLVPPAP EDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIG TDSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNR EQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPG KAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPL RNTERSKDWYKTMFKQIHKLNRDTPEENPYFPT YKFPELPEIQQTSEETKSCSVMSPRLECSGTVIA HCSLKLLDSSNPPTSASQVAGTADDDSDLYSPR YSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSA TLPLPARSSSLKSSSERNDWEPPDKKVDTRKYRA EPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLK NEPWYKFFSELEFGKPPPKKIWDYTPGDCSILP REDRKTNLDKDLSLCQTELEADLEKMETLNKAPS ANVPQSSAISPTPEISSETPGYIYSSNFHAVKR ESDGAPGDLTSLENERQIYKSVLEGGDIPLQGL SGLKRPSSSASTKDSESPRHFIPADYLESTEEFI RRRHDDKEKLLADQRRLKREQEEADIAARRHTG VIPTHHQFITNERFGDLLNIDDTAKRKSGSEMR PARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNW YEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTP VQVLEYGEAIAKFNFNGDTQVEMSFRKGERITL LRQVDENWYEGRIPGTSRQGIFPITYVDVIKRPL VKNPVDYMDLPFSSSPSRSATASPQPWREESGQ YERKAERGAGERGPGGPKISKKSCLKPSDVVRC LSTEQRLSDLNTPEESRPGKPLGSAFPGSEAEQT ERHRGGEQAGRKAARRGGSQQPQAQQRRVTPDR SQTSQDLFSYQALYSYIPQNDDELELRDGDIVD VMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL* ED*KPWRLFLLEEEASFMNRSF*LSQ*EN*YSG *SKKQKTGTEKCCV*NPSLSKVTVY*TGPN*CA EQKELKQIVFT*PLLGATSAFPLPSTSWVI*PEA *SRSRVSQKCLLLPQP*RAPISIIEPEGFKPKN ATRPPAYISQLPWSQLIL*RCWRSV*ATKTVPR QRWSPPHCPRPNPSLNLLRCGWGNRGKTEAPDAF SLLCSSAIDCPDVQRETHTRFAHENWGADGQAD RLCLFSE**SQEALWLWRPLVVHSFPISLAFRN GYLQDSAAAFIRALLLSFLFWLVFFWDSLELGGL FS*NTKNDVQ*FI*HTPMYSGCWGDNHKQDMPR VCRGSRSTPCRSSRITQTVVTRVVNLSTPWQGF SSD*SSNSATTSSNQDVCSLWGPDQKREAPVTPG LLGHNSVQFKDVYRPLLDPE*DKYRNDPFPAHQ KLRGDWGD*HRKMNLIKRDCDMC*EGCEGGRDE FSLEGS*KALSYCHLH*LTFKQLGCWKNLCLRVV HSWKYLEYFPESLNSHLPPQIHIQAHK*E*QF* VVGLCTEPLAVCIYLRITPGPLSQSLESLQVGK ICFQCLCLSCCHKYPS*DPISFPSPTRQPQYPHF LPIVLSNPVLRKETATNSFTLRCK*LIIGMSYL FPQTFVFKYDRAGP*SQGKRLWNWRG*AFWVEG DFLNFLKTQ*E*DLLFWKVCSTI*EHCFFFFVVV VVLRSLREYSKNAYARAICTAAFHRLWTVLANV FPGL*MQTINNTILSHSFFRGAS*LVGNFEHLF KYS*KIKPICKATFAYDASLTHLYISRNSGMPHQ FARL**NLVLKFASRRLPMYDETRNRDFQLLFC LQTFSNIKYLFLC*NVYTGLLIASATNWRHALQ HILIY*PCFRVKASPKLLIFCSLSGISKRKKK*C A*EVGL*ICIFNFV*PMYLPCIEK*F*KFEWKG VKEVMKFFCIFI*MKEFQITHLQIFSTKIAIVK C*NLR*VFYWGGKVTLISVTVFFSFLISLFWVFG FCSPIYLQSY*VLLLE*VTTKKVIF*KKNN*HY I*PINLKYCHLNYTLRACPMQT*IFLFIYFSSL QWIDLINRCVELLHLLYILFNKLYSELRG

Frame 1

AVQSPSCRRLVLPPP*VLNVMVVPKL**MAWHL AAMGKTKQLPTLYAHALFLLLKSFL*RQ*KTPQ A*FSLQTWILQKSALGRER*LSGPRLPTGKPQAV ALRALRKPGNTKANQVWSQSLLQQMSGGFLPVL MPMEMPSPLHSLPRATEVCIPTFLLTSPRMPLP PVQPSRR**LSLSTWLILTEGKKALPDLQHLWGL LAASPQSQRLPLPPHL*PSRL*MISFPLICRGG PTTASQPAPLAPLPPLARRHHPSHHHLRWSLLP RRTSAESRSLTSRELFRVPIPVLY*MKFLLPLLE LIPKPFHQLASLHPPIPPQRLSILLLCSCNTIE NSKNDSVAFQILSQKEEWESRTQHQPRKNPPHL ARLLKKEQRMTVGGW*RALRT*AMFPWMKWASHS GTLRDQKTGTRLCLNRSTN*TETLLKKTLISLR TNSLNFLKSSKLPKRQSLALSCHPGWSAVVQS* LTAASNS*TQAILPPQPPK*LGLQMMIQICTLPD THFLKTQNLPFLCLAQKVR*ATLMVRR*SRGRP HYPSQPALPH*SQAQKEMTGNPQIRK*TQENIV QSPRAFTNISLASLPF*PTKR*VGI*AQKR*I*R MNLGINSFRNWSLGNRLPKRYGIILLETALSFL ERIERLI*TKISASARQS*RQI*KKWRRLIKHP VQTCHRAQPSALLRKFLQRLLDIYILPTSMQ*RG NQTGLLGISLAWRMRDKFIKVSWKVVTSLFRA* VGSSDHPALLPLKIQNRQDILYQLITWNPRKNL FEDVMMIKRNF*RTRDDLNASKKRLILQLDATQA SFRRTISLSLMSALGTSSI*TILQKGNLGQR*D LPEPNLTLKLRH*RSFLCRREILFTFISKLIRT GMKENTTAGWESSHAPTSSFFLLLRRHSPKS*HQ CRFWNMEKLLLSLTLMVIHK*KCPSERVRGSHC SGR*MRTGTKGGSRGHPDKASSPSPTWM*SSDH W*KTLWITWTCLSPPPQVAVPLQAHSHGAKRVDN MRGKQRGGQAKEALVDPRSLRRAA*SLQTWSGA *VLNRDSQISTPLRRAGPASPWVALFQEVRLSR QSGIEVASRRGGKLLGEVGASNLKPSSEESPPTG VKPHKIYLAIKHYIAIYHRMMMSWNSAMEISLM SWKNVTMDGLLVLQEGQSSLVLFQATM*NLCIY KKTENHGDYFYWRRKHHS*TDLFS*VSRKINTVD KVRSKRQGQRSVVFKTQACLRLLCIRQGRTSVL SKKN*SKLYLLSRFWEPLQPFPSPPLLG*SDLK HSPGAELARNASCCPSLRELPSQSLSLKASSPRM QQDPQPTFLSSPGAS*SCNAAGGQSELPRLSLD KGGVPHTAQDQIPHSTC*GVDGETEAKLRHLMH SACCAAVPLTALMFREKRTQGLPMRIGEQMAKQI GYVCFLSDEVRKPCGSGGHLWFILFPYPWLLEM VTFRTVQLHLSEHYC*VFFSGLCFSGTV*NWEA YSHRTPKMMFSDSFNIHQCTLAAGGTTISKTCPG FAVAPDLLPVGVQGSHKR**PGL*I*VHPGKAS LQTEAAILPLPAATRTSVLCGGQIRRERPL*RP GCLVTTLSNSRMFIGLS*ILSETNTEMTHSLPTR NSEVIGETDTGK*T*SRETVICAKKGVREGEMN FPWRDPRKHCHIAISISSLLNN*GAGRTFV*G* FIAGNTWNIFQSL*TLIFPHRYTSKLTNRSSNSR W*GCVRNPWLSAYISELPQDHCPKV*SLYR*AK FVFNACASAAVTNTHLRIPSASHPPPDSHSTLT FSLLFFQILFSGKKLPLIHSH*GVND***E*VTS SHRHLFLSMTEQGLNPKGKGYGTGGGELSG*KE TS*ISLKPSKSKTCCFGRSAPPSKSTVFFFLLL LLFYGL*GNIVKMHMHVQFARQHFTDCGLYWLMC FLVFRCKPLITLSYLIVFSGVLLD**GILNTSL NTARK*NQFVKPHLHMMPASRICISPEIQVCLT NLPVFNKILC*NLHHVAFLCMTKQETEISNCSFV FRHLVI*STYFYAEMFIQVY**QVQLTGGMPCN TF*YISHASG*RQAPNSLSFAVSLGSVKEKKNN VLKKWDCKYVYLTLYSPCTYLV*KNNFKNLNGRG *RKS*SFFAFLFK*RNSK*LTYRFLAQK*PL*S VKIYDKYSIGEER*L*SQLQFFFPF*FHYFGFL VFAVLFICSRIKSYC*NRLLQKRLYSERKITDII YNQLI*SIAI*ITH*EHVLCRHRFFCSFIFLHC SGLI**IDVLNYYICCTYYLINFIQNCVA

Frame 2

QFRAPVADDLSCHHHEF*M*WWFQSCDEWLGTW QQWARQSNCRPFTRTLYFCC*NHSCEDSEKRLR PSSPYRHGSYKNLHWEGSGDSPGLVFLQGNPKQ *PCEPSGNPATRKQTRSGARAFFSR*VEAFFQC* CQWKCPALFTRCQGLQKCASQPSF*QVPGCHFL QCSPAGGNSCPSLPG*Y*QRARRHCQTSNTSGA SWLRPHNPSDCLCRLTSDLPDSR*FHSPSSAEVA PPQPASPRLWLLCPH*PDATILLTTTSAGPSCP GGPPQSLGA*PHGSCFEYRFQSSTK*SFFFPYW N*FPSLSIS*QAFIRLSLHNDCQSYYCALATQSR TAKTTQ*PFRSCLRKKSGRAGLSTNPGKTHLTW QGY*KKSKG*Q*AGGEEHSGLKRCFHG*SGHPT PEH*EIKRLVQDYV*TDPQTEQRHS*RKPLFPYV QIP*TS*NPANFRRDKVLLCHVTQAGVQWYSHS SLQPQTPRLKQSSHLSLPSSWDCR**FRSVLSQ ILIF*RHKISPFCASLKK*DELH*W*EGSQEVGH TTPPSPLFLTEVKLRKK*LGTPR*ESRHKKISC RAQEHLRISAWQVFRSDQRKDESGYKPRRDRFK E*TLV*ILFGIGVWETASQKDMGLYSWRLLYPS* RG*KD*SRQRSQPLPDRVRGRFRKNGDA**STQ CKRATELSHQPYSGNFFRDSWIYIFFQLPCSEE GIRRGSWGSH*LGE*ETNL*KCLGRW*HPSSGPE WAQATIQLCFH*RFRIAKTFYTS*LLGIHGRIY SKTS***RETFSGPETT*TRARRG*YCSSTPHR RHSDAPSVYH**ALWGPPQYRRYCKKEIWVRDET CQSQI*L*SSDTKGASSAEGRYCLHL*AN*SEL V*RRTPRPGGNLPTHLHRASSSC*EGTAQKVDT SAGFGIWRSYC*V*L*W*YTSRNVLQKG*EDHTA PAGR*ELVRREDPGDIPTRHLPHHLRGCDQATT GEKPCGLHGPAFLLLPKSQCHCKPTAMARREWT I*EESREGGRRKRPWWTQDL*EELLEAFRRGQVP EY*TETLRSQHP*GEPARQAPG*RFSRK*G*AD RAA*RWRAGGEESCSERWEPATSSPAAKSHPRQ ESNLTRFI*LSSII*LYTTE***VGTPRWRYR*C HGKM*RWMVCWYFKKDKAVWYFSRQLCKTFVSI RRLKTMEIIFIGGGSIIHEPIFLVESVGKLIQW IK*EAKDRDREVLCLKPKPV*GYCVLDRAELVC* AKRIEANCIYLAASGSHFSLSPPLHFLGNLT*S IVQEQS*PEMPPAAPALESSHLNH*A*RLQAQE CNKTPSLHFSAPLEPADPVTLLEVSLSYQDCP*T KVESPTLPKTKSLTQPAEVWMGKQRQN*GT*CI QPAVQQCH*LP*CSERNAHKVCP*ELGSRWPSR *VMSVF*VMKSGSPVALEATCGSFFSHILGF*KW LPSGQCSCIYQSTIAKFSFLACVFLGQFRIGRP ILIEHQK*CSVIHLTYTNVLWLLGGQP*ARHAQ GLPWLQIYSL*EFKDHTNGSNQGCESEYTLARLL FRLKQQFCHYQQQPGRLFFVGARSEERGPCDAR AAWSQLCPIQGCLSASLRS*VRQIQK*PIPCPP ETQR*LGRLTQENELNQERL*YVLRRV*GRER*I FPGGILESIVILPSPLAHF*TTRVLEEPLSEGS S*LEILGIFSRVSKLSSSPTDTHPSSQIGVAIL GGRVVYGTPGCLHISQNYPRTIVPKSRVFTGRQN LFSMPVPQLLSQIPILGSHQLPIPHQTATVPSL SPYCSFKSCSQERNCH*FIHTKV*MIDNRNELP LPTDICF*V*QSRALIPREKVMELEGVSFLGRRR LPEFP*NPVRVRPVVLEGLLHHLRALFFFFCCC CCFTVSEGI**KCICTCNLHGSISPIVDCIG*C VSWSLDANH**HYLIS*FFQGCFLISREF*TPL* IQLENKTNL*SHICI*CQPHAFVYLQKFRYASP ICPSLIKSCVKICITSPSYV*RNKKQRFPIALL SSDI**YKVPIFMLKCLYRFINSKCN*LAACLAT HFDILAMLPGKGKPQTPYLLQSLWDQ*KKKKIM CLRSGTVNMYI*LCIAHVPTLYRKIILKI*MEG GKGSHEVFLHFYLNEGIPNNSPTDF*HKNSHCKV LKFTISILLGRKGNSDLSYSFFFLFNFIILGFW FLQSYLSAVVLSPIARIGYYKKGYILKEK*LTL YITN*FKVLPFKLHTESMSYADIDFSVHLFFFIA VD*FDK*MC*ITTFAVHII**TLFRIAW