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Sequences

Sequence NM_006155

GTGGTGGGCTAGACGAGTTTCGCGCGGCCGCTCGCCGTCCCCCGCCCAGTCGTACTCGGCGCCCCAGCTCGGTGCTGCCGCCATCTTCTTGGAGGACAGG AGGAGAGGCGAAGGCTCCCCCTCCCCGTGATCGCTCCGCACTCCCGCCACCACCTGCCCTCCCGCGACCGCCTCTCTCCTCCTCAGTGGGCACTTGTCTC CTTCTAACAAACGGCCTTCCCCCCACTCCAGTTACCCACCGCAAGGCGAAGATTCTCATTACCTGTTCCACTCTTATAAGCATAAGAAAACCGAGCTCAT AAGACGAAGCTTCACAAAAGATGTCTAAGCAACAGCCAACTCAGTTTATAAATCCAGAAACACCTGGCTATGTTGGATTTGCAAACCTCCCCAATCAAGT TCACCGAAAATCAGTGAAAAAAGGTTTTGAGTTCACACTGATGGTGGTCGGTGAATCAGGTCTAGGAAAATCGACTCTCATAAACAGCCTATTCCTAACT GATCTGTACCCAGAAAGAGTCATACCTGGAGCAGCAGAAAAAATTGAAAGAACTGTCCAGATTGAGGCTTCAACTGTTGAAATTGAAGAGCGAGGGGTCA AGCTACGCCTGACAGTGGTAGATACCCCTGGCTATGGTGACGCTATCAACTGCAGAGATTGTTTTAAGACAATTATCTCCTATATTGATGAGCAATTTGA GAGGTACCTGCATGACGAGAGCGGCTTGAACAGGCGGCACATCATTGATAATAGGGTGCATTGTTGCTTTTACTTTATTTCACCTTTTGGACATGGACTT AAGCCCTTAGATGTGGCGTTTATGAAGGCAATACACAACAAGGTGAATATTGTGCCTGTCATTGCAAAAGCTGACACTCTCACCCTGAAGGAACGGGAGC GGCTGAAGAAAAGGATTCTGGATGAAATTGAAGAACATAACATCAAAATCTATCACTTACCTGATGCAGAATCAGATGAAGATGAAGATTTTAAAGAGCA GACTAGACTTCTCAAGGCTAGCATCCCATTCTCTGTGGTTGGATCCAATCAGTTGATTGAAGCCAAAGGAAAGAAGGTCAGAGGCCGCCTCTACCCCTGG GGTGTTGTGGAAGTGGAGAACCCAGAGCACAATGACTTTCTGAAGCTGAGAACCATGCTCATCACCCACATGCAGGATCTCCAGGAGGTGACCCAGGACC TTCATTATGAAAACTTCCGTTCTGAGAGACTCAAGAGAGGCGGCAGGAAAGTGGAGAATGAGGACATGAATAAAGACCAGATCTTGCTGGAAAAAGAAGC TGAGCTCCGCCGCATGCAAGAGATGATTGCAAGGATGCAGGCGCAGATGCAGATGCAGATGCAGGGCGGGGATGGCGATGGCGGGGCTCTCGGGCACCAC GTGTAAGGTGATGTGCACATATCAAGAAGTCAGAGAAAACACTTTCCTGGATAAAAAAGAAAACATTCCAGATGCATGATCCAGCTGTGTGTTTTCAATC CTTGGGAGGGTGCCATCCACATTTTAACAGTACCTGTGCCTGAGAATTTAATTTTTAAAAGACTTTGATGTGTTTTTGTATGAAGTACTTTTAACGTATG TATTTCATTGCTGTGTCACACTCTGTGTTTTGTGAGGTGAATGTCTTCCTTTTCTTTCTCCCTAACCACTAATGTTAGAATTGATTTCCAAGAATCGGCA TGTATACTTAATACTGAATTTCTTTGATTTAACTGACTTAACAACTGACTAACCATTGATGAGCACTCCTGATTTTTATCTAGAACATTCAGATTTACCA TAATGTTCCTTAGTGGTAGAGGTGTGTGCCTAGTGATGTAGAAAGATACACTGACTTGGTGCAAGGCCATCTGCTTACCACATCACACCACTTGGAGATC TTTGCTTCCTTGCTTTTATGTTTGTACACAACACCTAAAACCAGTTTTGCTGCTATAATTCTATACTGTTGATTCGTCTGCGATTTTATCTGTTAACCAA ATAAAACATAATAGAATTTCCTAATGAGATATATCTTTATACTTAAACAGCTTTTTTAGAGGTGAGTTTTAAAGAAGTCTCTTAATTCTGATGCTAGGTT GTTTTTAAAACCACTATGCAAAGAACTCACCACAAGCCACCTTTTGTAGTGTTCTCCACTAATACTGGTTATCCTGTGCTACAGAGAAAATCAAAGCAGT CATAAGCTCCAGTTTTCGTATTGCAAATAAGACTCTTACCTACAAAATGAGATTCAGTGAACTAATTTGGTTTTTACTCAACCAAATTAAAAATTTTTTT AAGGAAAATTAGCAGTTGGTCTATTCAGAATCAAACCTTTTTATATTTTATACTGCACTTTAGTGTATTTTCTGTCACTGTAGGTATAGAAGATCTGCCT CCCCTGTGGAAATTGGGGTCTGTTGGTGGGCGTGCCCCTGAAGCCTGGCTTGGGTTGAAAAGTGTTCCCGCCCTAAGGCCTTGGTGCCCTGAACCTCTGA TGCCTACCGGGTTCTCCTGATTTGAGTTTCCTTTAAATACTCCCTTTTTGAGTAATTTTCTGATGGGAGGAAAGTAGCAGTCATCATCTTTTTGTGTGCA GGCTGTCTCATTTATTTTTAGCCATTGTCGTTTCATTCATTTTGTGTAATATAAACCGTGTGTCATGTCAAAGTGAAAGACATTTCAAATCTGTAGCATA GGCTAGTGGGCAGGTCCGCACAGTCGAAGCCACACCTGGTCTGTTTTCTGTGCACTGTAGCCTTAGTGTCACCTTTCTTCTTGTGTCTCCTTATGGTACA CTCCAGCGGTTGCCTTTTTTATCATTTCTACTGAAGTTGGGAAATTCAACCCCAGAAATTGACAGATGAAAGGAGACAATGGTTGTGTAGGGAGATGGAG AAAATGCTTAATCTGAGGATGAGACAGGGTTTTTTCATTTTTGTGGGGGCTAGAAAAAACATAAAATGAGGCAGTTAAATAATAATAGTTAATGAAGGTG TGCTACAGAAAATAATCTGGTGTTCTTGCTAACTTTGCCCTTCACTGTTGCTTAATTGTGAACAGCCAAAAGCTATATGTTATGGCTTATTGTGTGAAGG TAACTAAGAAGTGGTGTTCCATGACTTCAGAGTACATCCATGCGGAGTCCATTATTTGAGTTTGACATTTAATAACTTTGCTGGAAAATCTGTAAAAAAG AAAAACAAGTTTGCTAGTGACTAAGCCCCGCATATGTGAGTGAAAGTACTTCAGGCACGCTGCCTCCTGGTAACAGCTATGCAGGGAGGGAGGACCCACA CTGCTACACTTCTGATCCCCTTTGGTTTTACTACCCAAATCTAAATAGATACTTTTGATAATAGATAACTGCTCTTTTACTAAGACATAGTCTCTACCTA TAGAAATGTATTTTGAAAACACTTATTTTACACAGCAATTTTGTATCCATTTAAACTAACCTTTTATCAATAAAGCACTATTGTTTAGATATTAAA

refseq_SEPT2.F2 (forward primer)
refseq_SEPT2.R2 (reverse primer)
Single exon skipping

Frame 0

VVG*TSFARPLAVPRPVVLGAPARCCRHLLGGQ EERRRLPLPVIAPHSRHHLPSRDRLSPPQWALVS F*QTAFPPLQLPTARRRFSLPVPLL*A*ENRAH KTKLHKRCLSNSQLSL*IQKHLAMLDLQTSPIK FTENQ*KKVLSSH*WWSVNQV*ENRLS*TAYS*L ICTQKESYLEQQKKLKELSRLRLQLLKLKSEGS SYA*QW*IPLAMVTLSTAEIVLRQLSPILMSNL RGTCMTRAA*TGGTSLIIGCIVAFTLFHLLDMDL SP*MWRL*RQYTTR*ILCLSLQKLTLSP*RNGS G*RKGFWMKLKNITSKSITYLMQNQMKMKILKS RLDFSRLASHSLWLDPIS*LKPKERRSEAASTPG VLWKWRTQSTMTF*S*EPCSSPTCRISRR*PRT FIMKTSVLRDSREAAGKWRMRT*IKTRSCWKKK LSSAACKR*LQGCRRRCRCRCRAGMAMAGLSGTT CKVMCTYQEVRENTFLDKKENIPDA*SSCVFSI LGRVPSTF*QYLCLRI*FLKDFDVFLYEVLLTY VFHCCVTLCVL*GECLPFLSP*PLMLELISKNRH VYLILNFFDLTDLTTD*PLMSTPDFYLEHSDLP *CSLVVEVCA**CRKIH*LGARPSAYHITPLGD LCFLAFMFVHNT*NQFCCYNSILLIRLRFYLLTK *NIIEFPNEIYLYT*TAFLEVSFKEVS*F*C*V VFKTTMQRTHHKPPFVVFSTNTGYPVLQRKSKQ S*APVFVLQIRLLPTK*DSVN*FGFYSTKLKIFL RKISSWSIQNQTFLYFILHFSVFSVTVGIEDLP PLWKLGSVGGRAPEAWLGLKSVPALRPWCPEPL MPTGFS*FEFPLNTPFLSNFLMGGK*QSSSFCVQ AVSFIFSHCRFIHFV*YKPCVMSK*KTFQICSI G*WAGPHSRSHTWSVFCAL*P*CHLSSCVSLWY TPAVAFFIISTEVGKFNPRN*QMKGDNGCVGRWR KCLI*G*DRVFSFLWGLEKT*NEAVK***LMKV CYRK*SGVLANFALHCCLIVNSQKLYVMAYCVK VTKKWCSMTSEYIHAESII*V*HLITLLENL*KR KTSLLVTKPRICE*KYFRHAASW*QLCREGGPT LLHF*SPLVLLPKSK*ILLIIDNCSFTKT*SLP IEMYFENTYFTQQFCIHLN*PFINKALLFRY*

Frame 1

WWARRVSRGRSPSPAQSYSAPQLGAAAIFLEDR RRGEGSPSP*SLRTPATTCPPATASLLLSGHLS PSNKRPSPHSSYPPQGEDSHYLFHSYKHKKTELI RRSFTKDV*ATANSVYKSRNTWLCWICKPPQSS SPKISEKRF*VHTDGGR*IRSRKIDSHKQPIPN *SVPRKSHTWSSRKN*KNCPD*GFNC*N*RARGQ ATPDSGRYPWLW*RYQLQRLF*DNYLLY**AI* EVPA*RERLEQAAHH***GALLLLLYFTFWTWT *ALRCGVYEGNTQQGEYCACHCKS*HSHPEGTGA AEEKDSG*N*RT*HQNLSLT*CRIR*R*RF*RA D*TSQG*HPILCGWIQSVD*SQRKEGQRPPLPL GCCGSGEPRAQ*LSEAENHAHHPHAGSPGGDPGP SL*KLPF*ETQERRQESGE*GHE*RPDLAGKRS *APPHARDDCKDAGADADADAGRGWRWRGSRAP RVR*CAHIKKSEKTLSWIKKKTFQMHDPAVCFQS LGGCHPHFNSTCA*EFNF*KTLMCFCMKYF*RM YFIAVSHSVFCEVNVFLFFLPNH*C*N*FPRIG MYT*Y*ISLI*LT*QLTNH**ALLIFI*NIQIYH NVP*W*RCVPSDVERYTDLVQGHLLTTSHHLEI FASLLLCLYTTPKTSFAAIILYC*FVCDFIC*P NKT**NFLMRYIFILKQLF*R*VLKKSLNSDARL FLKPLCKELTTSHLL*CSPLILVILCYRENQSS HKLQFSYCK*DSYLQNEIQ*TNLVFTQPN*KFF *GKLAVGLFRIKPFYILYCTLVYFLSL*V*KICL PCGNWGLLVGVPLKPGLG*KVFPP*GLGALNL* CLPGSPDLSFL*ILPF*VIF*WEESSSHHLFVC RLSHLFLAIVVSFILCNINRVSCQSERHFKSVA* ASGQVRTVEATPGLFSVHCSLSVTFLLVSPYGT LQRLPFLSFLLKLGNSTPEIDR*KETMVV*GDG ENA*SEDETGFFHFCGG*KKHKMRQLNNNS**RC ATENNLVFLLTLPFTVA*L*TAKSYMLWLIV*R *LRSGVP*LQSTSMRSPLFEFDI**LCWKICKK EKQVC**LSPAYVSESTSGTLPPGNSYAGREDPH CYTSDPLWFYYPNLNRYF***ITALLLRHSLYL *KCILKTLILHSNFVSI*TNLLSIKHYCLDIK

Frame 2

GGLDEFRAAARRPPPSRTRRPSSVLPPSSWRTG GEAKAPPPRDRSALPPPPALPRPPLSSSVGTCL LLTNGLPPTPVTHRKAKILITCSTLISIRKPSS *DEASQKMSKQQPTQFINPETPGYVGFANLPNQV HRKSVKKGFEFTLMVVGESGLGKSTLINSLFLT DLYPERVIPGAAEKIERTVQIEASTVEIEERGV KLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFE RYLHDESGLNRRHIIDNRVHCCFYFISPFGHGL KPLDVAFMKAIHNKVNIVPVIAKADTLTLKERE RLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQ TRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPW GVVEVENPEHNDFLKLRTMLITHMQDLQEVTQD LHYENFRSERLKRGGRKVENEDMNKDQILLEKEA ELRRMQEMIARMQAQMQMQMQGGDGDGGALGHH V*GDVHISRSQRKHFPG*KRKHSRCMIQLCVFN PWEGAIHILTVPVPENLIFKRL*CVFV*STFNVC ISLLCHTLCFVR*MSSFSFSLTTNVRIDFQESA CILNTEFL*FN*LNN*LTIDEHS*FLSRTFRFT IMFLSGRGVCLVM*KDTLTWCKAICLPHHTTWRS LLPCFYVCTQHLKPVLLL*FYTVDSSAILSVNQ IKHNRIS**DISLYLNSFFRGEF*RSLLILMLG CF*NHYAKNSPQATFCSVLH*YWLSCATEKIKAV ISSSFRIANKTLTYKMRFSELIWFLLNQIKNFF KEN*QLVYSESNLFIFYTAL*CIFCHCRYRRSA SPVEIGVCWWACP*SLAWVEKCSRPKALVP*TSD AYRVLLI*VSFKYSLFE*FSDGRKVAVIIFLCA GCLIYF*PLSFHSFCVI*TVCHVKVKDISNL*H RLVGRSAQSKPHLVCFLCTVALVSPFFLCLLMVH SSGCLFYHFY*SWEIQPQKLTDERRQWLCREME KMLNLRMRQGFFIFVGARKNIK*GS*IIIVNEG VLQKIIWCSC*LCPSLLLNCEQPKAICYGLLCEG N*EVVFHDFRVHPCGVHYLSLTFNNFAGKSVKK KNKFASD*APHM*VKVLQARCLLVTAMQGGRTH TATLLIPFGFTTQI*IDTFDNR*LLFY*DIVSTY RNVF*KHLFYTAILYPFKLTFYQ*STIV*IL

Sequence NM_001008491

GTGGTGGGCTAGACGAGTTTCGCGCGGCCGCTCGCCGTCCCCCGCCCAGTCGTACTCGGCGCCCCAGCTCGGTGCTGCCGCCATCTTCTTGGAGGACAGG AGGAGAGGCGAAGGCTCCCCCTCCCCGTGATCGCTCCGCACTCCCGCCACCACCTGCCCTCCCGCGACCGCCTCTCTCCTCCTCAGTGGGCACTTGTCTC CTTCTAACAAACGGCCTTCCCCCCACTCCAGTTACCCACCGCAAGGCGAAGATTCTCATTACCTGTTCCACTCTTATAAGCATAAGAAAACCGAGCTCAT AAGCATACAGAAACTGCTGTAAAAGAAGAAGTTGTGGGTATTTTTTTTTTTTTTTTTGTCTGGAGGAATGGGGACACCAAAACTCATTTGGCAGCAGAGG TGAGACGAAGCTTCACAAAAGATGTCTAAGCAACAGCCAACTCAGTTTATAAATCCAGAAACACCTGGCTATGTTGGATTTGCAAACCTCCCCAATCAAG TTCACCGAAAATCAGTGAAAAAAGGTTTTGAGTTCACACTGATGGTGGTCGGTGAATCAGGTCTAGGAAAATCGACTCTCATAAACAGCCTATTCCTAAC TGATCTGTACCCAGAAAGAGTCATACCTGGAGCAGCAGAAAAAATTGAAAGAACTGTCCAGATTGAGGCTTCAACTGTTGAAATTGAAGAGCGAGGGGTC AAGCTACGCCTGACAGTGGTAGATACCCCTGGCTATGGTGACGCTATCAACTGCAGAGATTGTTTTAAGACAATTATCTCCTATATTGATGAGCAATTTG AGAGGTACCTGCATGACGAGAGCGGCTTGAACAGGCGGCACATCATTGATAATAGGGTGCATTGTTGCTTTTACTTTATTTCACCTTTTGGACATGGACT TAAGCCCTTAGATGTGGCGTTTATGAAGGCAATACACAACAAGGTGAATATTGTGCCTGTCATTGCAAAAGCTGACACTCTCACCCTGAAGGAACGGGAG CGGCTGAAGAAAAGGATTCTGGATGAAATTGAAGAACATAACATCAAAATCTATCACTTACCTGATGCAGAATCAGATGAAGATGAAGATTTTAAAGAGC AGACTAGACTTCTCAAGGCTAGCATCCCATTCTCTGTGGTTGGATCCAATCAGTTGATTGAAGCCAAAGGAAAGAAGGTCAGAGGCCGCCTCTACCCCTG GGGTGTTGTGGAAGTGGAGAACCCAGAGCACAATGACTTTCTGAAGCTGAGAACCATGCTCATCACCCACATGCAGGATCTCCAGGAGGTGACCCAGGAC CTTCATTATGAAAACTTCCGTTCTGAGAGACTCAAGAGAGGCGGCAGGAAAGTGGAGAATGAGGACATGAATAAAGACCAGATCTTGCTGGAAAAAGAAG CTGAGCTCCGCCGCATGCAAGAGATGATTGCAAGGATGCAGGCGCAGATGCAGATGCAGATGCAGGGCGGGGATGGCGATGGCGGGGCTCTCGGGCACCA CGTGTAAGGTGATGTGCACATATCAAGAAGTCAGAGAAAACACTTTCCTGGATAAAAAAGAAAACATTCCAGATGCATGATCCAGCTGTGTGTTTTCAAT CCTTGGGAGGGTGCCATCCACATTTTAACAGTACCTGTGCCTGAGAATTTAATTTTTAAAAGACTTTGATGTGTTTTTGTATGAAGTACTTTTAACGTAT GTATTTCATTGCTGTGTCACACTCTGTGTTTTGTGAGGTGAATGTCTTCCTTTTCTTTCTCCCTAACCACTAATGTTAGAATTGATTTCCAAGAATCGGC ATGTATACTTAATACTGAATTTCTTTGATTTAACTGACTTAACAACTGACTAACCATTGATGAGCACTCCTGATTTTTATCTAGAACATTCAGATTTACC ATAATGTTCCTTAGTGGTAGAGGTGTGTGCCTAGTGATGTAGAAAGATACACTGACTTGGTGCAAGGCCATCTGCTTACCACATCACACCACTTGGAGAT CTTTGCTTCCTTGCTTTTATGTTTGTACACAACACCTAAAACCAGTTTTGCTGCTATAATTCTATACTGTTGATTCGTCTGCGATTTTATCTGTTAACCA AATAAAACATAATAGAATTTCCTAATGAGATATATCTTTATACTTAAACAGCTTTTTTAGAGGTGAGTTTTAAAGAAGTCTCTTAATTCTGATGCTAGGT TGTTTTTAAAACCACTATGCAAAGAACTCACCACAAGCCACCTTTTGTAGTGTTCTCCACTAATACTGGTTATCCTGTGCTACAGAGAAAATCAAAGCAG TCATAAGCTCCAGTTTTCGTATTGCAAATAAGACTCTTACCTACAAAATGAGATTCAGTGAACTAATTTGGTTTTTACTCAACCAAATTAAAAATTTTTT TAAGGAAAATTAGCAGTTGGTCTATTCAGAATCAAACCTTTTTATATTTTATACTGCACTTTAGTGTATTTTCTGTCACTGTAGGTATAGAAGATCTGCC TCCCCTGTGGAAATTGGGGTCTGTTGGTGGGCGTGCCCCTGAAGCCTGGCTTGGGTTGAAAAGTGTTCCCGCCCTAAGGCCTTGGTGCCCTGAACCTCTG ATGCCTACCGGGTTCTCCTGATTTGAGTTTCCTTTAAATACTCCCTTTTTGAGTAATTTTCTGATGGGAGGAAAGTAGCAGTCATCATCTTTTTGTGTGC AGGCTGTCTCATTTATTTTTAGCCATTGTCGTTTCATTCATTTTGTGTAATATAAACCGTGTGTCATGTCAAAGTGAAAGACATTTCAAATCTGTAGCAT AGGCTAGTGGGCAGGTCCGCACAGTCGAAGCCACACCTGGTCTGTTTTCTGTGCACTGTAGCCTTAGTGTCACCTTTCTTCTTGTGTCTCCTTATGGTAC ACTCCAGCGGTTGCCTTTTTTATCATTTCTACTGAAGTTGGGAAATTCAACCCCAGAAATTGACAGATGAAAGGAGACAATGGTTGTGTAGGGAGATGGA GAAAATGCTTAATCTGAGGATGAGACAGGGTTTTTTCATTTTTGTGGGGGCTAGAAAAAACATAAAATGAGGCAGTTAAATAATAATAGTTAATGAAGGT GTGCTACAGAAAATAATCTGGTGTTCTTGCTAACTTTGCCCTTCACTGTTGCTTAATTGTGAACAGCCAAAAGCTATATGTTATGGCTTATTGTGTGAAG GTAACTAAGAAGTGGTGTTCCATGACTTCAGAGTACATCCATGCGGAGTCCATTATTTGAGTTTGACATTTAATAACTTTGCTGGAAAATCTGTAAAAAA GAAAAACAAGTTTGCTAGTGACTAAGCCCCGCATATGTGAGTGAAAGTACTTCAGGCACGCTGCCTCCTGGTAACAGCTATGCAGGGAGGGAGGACCCAC ACTGCTACACTTCTGATCCCCTTTGGTTTTACTACCCAAATCTAAATAGATACTTTTGATAATAGATAACTGCTCTTTTACTAAGACATAGTCTCTACCT ATAGAAATGTATTTTGAAAACACTTATTTTACACAGCAATTTTGTATCCATTTAAACTAACCTTTTATCAATAAAGCACTATTGTTTAGATATTAAA

refseq_SEPT2.F2 (forward primer)
refseq_SEPT2.R2 (reverse primer)
Single exon skipping

Frame 0

VVG*TSFARPLAVPRPVVLGAPARCCRHLLGGQ EERRRLPLPVIAPHSRHHLPSRDRLSPPQWALVS F*QTAFPPLQLPTARRRFSLPVPLL*A*ENRAH KHTETAVKEEVVGIFFFFFVWRNGDTKTHLAAE VRRSFTKDV*ATANSVYKSRNTWLCWICKPPQSS SPKISEKRF*VHTDGGR*IRSRKIDSHKQPIPN *SVPRKSHTWSSRKN*KNCPD*GFNC*N*RARG QATPDSGRYPWLW*RYQLQRLF*DNYLLY**AI* EVPA*RERLEQAAHH***GALLLLLYFTFWTWT *ALRCGVYEGNTQQGEYCACHCKS*HSHPEGTG AAEEKDSG*N*RT*HQNLSLT*CRIR*R*RF*RA D*TSQG*HPILCGWIQSVD*SQRKEGQRPPLPL GCCGSGEPRAQ*LSEAENHAHHPHAGSPGGDPG PSL*KLPF*ETQERRQESGE*GHE*RPDLAGKRS *APPHARDDCKDAGADADADAGRGWRWRGSRAP RVR*CAHIKKSEKTLSWIKKKTFQMHDPAVCFQ SLGGCHPHFNSTCA*EFNF*KTLMCFCMKYF*RM YFIAVSHSVFCEVNVFLFFLPNH*C*N*FPRIG MYT*Y*ISLI*LT*QLTNH**ALLIFI*NIQIY HNVP*W*RCVPSDVERYTDLVQGHLLTTSHHLEI FASLLLCLYTTPKTSFAAIILYC*FVCDFIC*P NKT**NFLMRYIFILKQLF*R*VLKKSLNSDAR LFLKPLCKELTTSHLL*CSPLILVILCYRENQSS HKLQFSYCK*DSYLQNEIQ*TNLVFTQPN*KFF *GKLAVGLFRIKPFYILYCTLVYFLSL*V*KIC LPCGNWGLLVGVPLKPGLG*KVFPP*GLGALNL* CLPGSPDLSFL*ILPF*VIF*WEESSSHHLFVC RLSHLFLAIVVSFILCNINRVSCQSERHFKSVA *ASGQVRTVEATPGLFSVHCSLSVTFLLVSPYGT LQRLPFLSFLLKLGNSTPEIDR*KETMVV*GDG ENA*SEDETGFFHFCGG*KKHKMRQLNNNS**R CATENNLVFLLTLPFTVA*L*TAKSYMLWLIV*R *LRSGVP*LQSTSMRSPLFEFDI**LCWKICKK EKQVC**LSPAYVSESTSGTLPPGNSYAGREDP HCYTSDPLWFYYPNLNRYF***ITALLLRHSLYL *KCILKTLILHSNFVSI*TNLLSIKHYCLDIK

Frame 1

WWARRVSRGRSPSPAQSYSAPQLGAAAIFLEDR RRGEGSPSP*SLRTPATTCPPATASLLLSGHLS PSNKRPSPHSSYPPQGEDSHYLFHSYKHKKTELI SIQKLL*KKKLWVFFFFFLSGGMGTPKLIWQQR *DEASQKMSKQQPTQFINPETPGYVGFANLPNQ VHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLT DLYPERVIPGAAEKIERTVQIEASTVEIEERGV KLRLTVVDTPGYGDAINCRDCFKTIISYIDEQF ERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGL KPLDVAFMKAIHNKVNIVPVIAKADTLTLKERE RLKKRILDEIEEHNIKIYHLPDAESDEDEDFKE QTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPW GVVEVENPEHNDFLKLRTMLITHMQDLQEVTQD LHYENFRSERLKRGGRKVENEDMNKDQILLEKE AELRRMQEMIARMQAQMQMQMQGGDGDGGALGHH V*GDVHISRSQRKHFPG*KRKHSRCMIQLCVFN PWEGAIHILTVPVPENLIFKRL*CVFV*STFNV CISLLCHTLCFVR*MSSFSFSLTTNVRIDFQESA CILNTEFL*FN*LNN*LTIDEHS*FLSRTFRFT IMFLSGRGVCLVM*KDTLTWCKAICLPHHTTWR SLLPCFYVCTQHLKPVLLL*FYTVDSSAILSVNQ IKHNRIS**DISLYLNSFFRGEF*RSLLILMLG CF*NHYAKNSPQATFCSVLH*YWLSCATEKIKA VISSSFRIANKTLTYKMRFSELIWFLLNQIKNFF KEN*QLVYSESNLFIFYTAL*CIFCHCRYRRSA SPVEIGVCWWACP*SLAWVEKCSRPKALVP*TS DAYRVLLI*VSFKYSLFE*FSDGRKVAVIIFLCA GCLIYF*PLSFHSFCVI*TVCHVKVKDISNL*H RLVGRSAQSKPHLVCFLCTVALVSPFFLCLLMV HSSGCLFYHFY*SWEIQPQKLTDERRQWLCREME KMLNLRMRQGFFIFVGARKNIK*GS*IIIVNEG VLQKIIWCSC*LCPSLLLNCEQPKAICYGLLCE GN*EVVFHDFRVHPCGVHYLSLTFNNFAGKSVKK KNKFASD*APHM*VKVLQARCLLVTAMQGGRTH TATLLIPFGFTTQI*IDTFDNR*LLFY*DIVST YRNVF*KHLFYTAILYPFKLTFYQ*STIV*IL

Frame 2

GGLDEFRAAARRPPPSRTRRPSSVLPPSSWRTG GEAKAPPPRDRSALPPPPALPRPPLSSSVGTCL LLTNGLPPTPVTHRKAKILITCSTLISIRKPSS *AYRNCCKRRSCGYFFFFFCLEEWGHQNSFGSRG ETKLHKRCLSNSQLSL*IQKHLAMLDLQTSPIK FTENQ*KKVLSSH*WWSVNQV*ENRLS*TAYS* LICTQKESYLEQQKKLKELSRLRLQLLKLKSEGS SYA*QW*IPLAMVTLSTAEIVLRQLSPILMSNL RGTCMTRAA*TGGTSLIIGCIVAFTLFHLLDMD LSP*MWRL*RQYTTR*ILCLSLQKLTLSP*RNGS G*RKGFWMKLKNITSKSITYLMQNQMKMKILKS RLDFSRLASHSLWLDPIS*LKPKERRSEAASTP GVLWKWRTQSTMTF*S*EPCSSPTCRISRR*PRT FIMKTSVLRDSREAAGKWRMRT*IKTRSCWKKK LSSAACKR*LQGCRRRCRCRCRAGMAMAGLSGT TCKVMCTYQEVRENTFLDKKENIPDA*SSCVFSI LGRVPSTF*QYLCLRI*FLKDFDVFLYEVLLTY VFHCCVTLCVL*GECLPFLSP*PLMLELISKNR HVYLILNFFDLTDLTTD*PLMSTPDFYLEHSDLP *CSLVVEVCA**CRKIH*LGARPSAYHITPLGD LCFLAFMFVHNT*NQFCCYNSILLIRLRFYLLT K*NIIEFPNEIYLYT*TAFLEVSFKEVS*F*C*V VFKTTMQRTHHKPPFVVFSTNTGYPVLQRKSKQ S*APVFVLQIRLLPTK*DSVN*FGFYSTKLKIF LRKISSWSIQNQTFLYFILHFSVFSVTVGIEDLP PLWKLGSVGGRAPEAWLGLKSVPALRPWCPEPL MPTGFS*FEFPLNTPFLSNFLMGGK*QSSSFCV QAVSFIFSHCRFIHFV*YKPCVMSK*KTFQICSI G*WAGPHSRSHTWSVFCAL*P*CHLSSCVSLWY TPAVAFFIISTEVGKFNPRN*QMKGDNGCVGRW RKCLI*G*DRVFSFLWGLEKT*NEAVK***LMKV CYRK*SGVLANFALHCCLIVNSQKLYVMAYCVK VTKKWCSMTSEYIHAESII*V*HLITLLENL*K RKTSLLVTKPRICE*KYFRHAASW*QLCREGGPT LLHF*SPLVLLPKSK*ILLIIDNCSFTKT*SLP IEMYFENTYFTQQFCIHLN*PFINKALLFRY*