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Sequences

Sequence NM_182742

GGCAGTTAGCCCGCCCGCTCGGCGCAGGGCGTGGCTTCTCGTAGCCATTAGGAAACAGCAACCCTTTCACCTCAGTTTTCTTCACTCCGGCATTTGCAGC AGAGCGAAAGGTGGTCGAGTCCTGAAGGAGGGCCTGATGTCTTCATCATTCTCAAATTCTTGTAAGCTCTGCGTCGGGTGAAACCAGACAAAGCCGCGAG CCCAGGGATGGGAGCACGCGGGGGACGGCCTGCCGGCGGGGACGACAGCATTGCGCCTGGGTGCAGCAGTGTGCGTCTCGGGGAAGGGAAGATATTTTAA GGCGTGTCTGAGCAGACGGGGAGGCTTTTCCAAACCCAGGCAGCTTCGTGGCGTGTGCGGTTTCGACCCGGTCACACAAAGCTTCAGCATGTCATGTGGC TTATCAGGAGGGCAGACTTCAAAAGCTACTAAAAATGAACGGCCCTGAAGATCTTCCCAAGTCCTATGACTATGACCTTATCATCATTGGAGGTGGCTCA GGAGGTCTGGCAGCTGCTAAGGAGGCAGCCCAATATGGCAAGAAGGTGATGGTCCTGGACTTTGTCACTCCCACCCCTCTTGGAACTAGATGGGGTCTCG GAGGAACATGTGTGAATGTGGGTTGCATACCTAAAAAACTGATGCATCAAGCAGCTTTGTTAGGACAAGCCCTGCAAGACTCTCGAAATTATGGATGGAA AGTCGAGGAGACAGTTAAGCATGATTGGGACAGAATGATAGAAGCTGTACAGAATCACATTGGCTCTTTGAATTGGGGCTACCGAGTAGCTCTGCGGGAG AAAAAAGTCGTCTATGAGAATGCTTATGGGCAATTTATTGGTCCTCACAGGATTAAGGCAACAAATAATAAAGGCAAAGAAAAAATTTATTCAGCAGAGA GATTTCTCATTGCCACTGGTGAAAGACCACGTTACTTGGGCATCCCTGGTGACAAAGAATACTGCATCAGCAGTGATGATCTTTTCTCCTTGCCTTACTG CCCGGGTAAGACCCTGGTTGTTGGAGCATCCTATGTCGCTTTGGAGTGCGCTGGATTTCTTGCTGGTATTGGTTTAGACGTCACTGTTATGGTTAGGTCC ATTCTTCTTAGAGGATTTGACCAGGACATGGCCAACAAAATTGGTGAACACATGGAAGAACATGGCATCAAGTTTATAAGACAGTTCGTACCAATTAAAG TTGAACAAATTGAAGCAGGGACACCAGGCCGACTCAGAGTAGTAGCTCAGTCCACCAATAGTGAGGAAATCATTGAAGGAGAATATAATACGGTGATGCT GGCAATAGGAAGAGATGCTTGCACAAGAAAAATTGGCTTAGAAACCGTAGGGGTGAAGATAAATGAAAAGACTGGAAAAATACCTGTCACAGATGAAGAA CAGACCAATGTGCCTTACATCTATGCCATTGGCGATATATTGGAGGATAAGGTGGAGCTCACCCCAGTTGCAATCCAGGCAGGAAGATTGCTGGCTCAGA GGCTCTATGCAGGTTCCACTGTCAAGTGTGACTATGAAAATGTTCCAACCACTGTATTTACTCCTTTGGAATATGGTGCTTGTGGCCTTTCTGAGGAGAA AGCTGTGGAGAAGTTTGGGGAAGAAAATATTGAGGTTTACCATAGTTACTTTTGGCCATTGGAATGGACGATTCCGTCAAGAGATAACAACAAATGTTAT GCAAAAATAATCTGTAATACTAAAGACAATGAACGTGTTGTGGGCTTTCACGTACTGGGTCCAAATGCTGGAGAAGTTACACAAGGCTTTGCAGCTGCGC TCAAATGTGGACTGACCAAAAAGCAGCTGGACAGCACAATTGGAATCCACCCTGTCTGTGCAGAGGTATTCACAACATTGTCTGTGACCAAGCGCTCTGG GGCAAGCATCCTCCAGGCTGGCTGCTGAGGTTAAGCCCCAGTGTGGATGCTGTTGCCAAGACTGCAAACCACTGGCTCGTTTCCGTGCCCAAATCCAAGG CGAAGTTTTCTAGAGGGTTCTTGGGCTCTTGGCACCTGCGTGTCCTGTGCTTACCACCGCCCAAGGCCCCCTTGGATCTCTTGGATAGGAGTTGGTGAAT AGAAGGCAGGCAGCATCACACTGGGGTCACTGACAGACTTGAAGCTGACATTTGGCAGGGCATCGAAGGGATGCATCCATGAAGTCACCAGTCTCAAGCC CATGTGGTAGGCGGTGATGGAACAACTGTCAAATCAGTTTTAGCATGACCTTTCCTTGTGGATTTTCTTATTCTCGTTGTCAAGTTTTCTAGGGTTGAAT TTTTTTCTTTTTTCTCCATGGTGTTAATGATATTAGAGATGAAAAACGTTAGCAGTTGATTTTTGTCCAAAAGCAAGTCATGGCTAGAGTATCCATGCAA GGTGTCTTGTTGCATGGAAGGGATAGTTTGGCTCCCTTGGAGGCTATGTAGGCTTGTCCCGGGAAAGAGAACTGTCCTGCAGCTGAAATGGACTGTTCTT TACTGACCTGCTCAGCAGTTTCTTCTCTCATATATTCCCAAAACAAGTACATCTGCGATCAACTCTAGCCAAATTTGCCCCTGTGTGCTACATGATGGAT GATTATTATTTTAAGGTCTGTTTAGGAAGGGAAATGGCTACTTGGCCAGCCATTGCCTGGCATTTGGTAGTATAGTATGATTCTCACCATTATTTGTCAT GGAGGCAGACATACACCAGAAATGGGGGAGAAACAGTACATATCTTTCTGTCTTTAGTTTATTGTGTGCTGGTCTAAGCAAGCTGAGATCATTTGCAATG GAAAACACGTAACTTGTTTAAAAGTTTTTCTGGTAGCTTTAGCTTTATGCTAAAAAAAATAATGACATTGGGTATCTATTTCTTTCTAAGACTACATTAG TAGGAAAATAAGTCTTTTCATGCTTATGATTTAGCTGTTTTGTGGTAATTGCTTTTTAAAGGAAGTTATTAATATCATAAGTTATTATTAATATTTTGAA CACAGGTGGATGTGAAGGATTTTCATTTAAAAACCAAGTGGTTTTGACTTTTTCTGTTGAATGAACAACTGTGCCTTGTGGAATTTTTGCAGAAGTGTTT ATGCTTTGTTAGCATTTCAACTTGCATTATTATAAAGAGGTATTAATGCCTCAGTTATGTGTTTGTCAATGTACTGGCTGAGGATTCTATCTCAGCTGTC TTTTCTAACTGTGTAGGTTGAGTTTTGAACACGTGCTTGTGGACATCAGGCCTCCTGCCAGCAGTTCTTGAAGCTTCTTTTTCATTCCTGCTACTCTACC TGTATTTCTCAGTTGCAGCACTGAGTGGTCAAAATACATTTCTGGGCCACCTCAGGGAACCCATGCATCTGCCTGGCATTTAGGCAGCAGAGCCCCTGAC CGTCCCCCACAGGGCTCTGCCTCACGTCCTCATCTCATTTGGCTGTGTAAAGAAATGGGAAAAGGGAAAAGGAGAGAGCAATTGAGGCAGTTGACCATAT TCAGTTTTATTTATTTATTTTTAATTTGTTTTTTTCTCCAAGTCCACCAGTCTCTGAAATTAGAACAGTAGGCGGTATGAGATAATCAGGCCTAATCATG TTGTGATTCTCTTTTCTTAGTGGAGTGGAATGTTCTATCCCCACAAGAAGGATTATATCTTATAGACTTGTCTTGTTCAGATTCTGTATTTACCCATTTT ATTGAAACATATACTAAGTTCCATGTATTTTTGTTACAAATCTTCTGAAAAAAAACAAAACAATGTGAAACATTAAAATTAAAAGGCATTAATAATA

refseq_TXNRD1.F2 (forward primer)
refseq_TXNRD1.R2 (reverse primer)
Single exon skipping

Frame 0

GS*PARSAQGVASRSH*ETATLSPQFSSLRHLQ QSERWSSPEGGPDVFIILKFL*ALRRVKPDKAAS PGMGARGGRPAGGDDSIAPGCSSVRLGEGKIF* GVSEQTGRLFQTQAASWRVRFRPGHTKLQHVMW LIRRADFKSY*K*TALKIFPSPMTMTLSSLEVAQ EVWQLLRRQPNMARR*WSWTLSLPPLLELDGVS EEHV*MWVAYLKN*CIKQLC*DKPCKTLEIMDG KSRRQLSMIGTE**KLYRITLAL*IGATE*LCGR KKSSMRMLMGNLLVLTGLRQQIIKAKKKFIQQR DFSLPLVKDHVTWASLVTKNTASAVMIFSPCLT ARVRPWLLEHPMSLWSALDFLLVLV*TSLLWLGP FFLEDLTRTWPTKLVNTWKNMASSL*DSSYQLK LNKLKQGHQADSE**LSPPIVRKSLKENIIR*C WQ*EEMLAQEKLA*KP*G*R*MKRLEKYLSQMKN RPMCLTSMPLAIYWRIRWSSPQLQSRQEDCWLR GSMQVPLSSVTMKMFQPLYLLLWNMVLVAFLRR KLWRSLGKKILRFTIVTFGHWNGRFRQEITTNVM QK*SVILKTMNVLWAFTYWVQMLEKLHKALQLR SNVD*PKSSWTAQLESTLSVQRYSQHCL*PSAL GQASSRLAAEVKPQCGCCCQDCKPLARFRAQIQG EVF*RVLGLLAPACPVLTTAQGPLGSLG*ELVN RRQAASHWGH*QT*S*HLAGHRRDASMKSPVSS PCGRR*WNNCQISFSMTFPCGFSYSRCQVF*G*I FFFFLHGVNDIRDEKR*QLIFVQKQVMARVSMQ GVLLHGRDSLAPLEAM*ACPGKENCPAAEMDCS LLTCSAVSSLIYSQNKYICDQL*PNLPLCAT*WM IIILRSV*EGKWLLGQPLPGIW*YSMILTIICH GGRHTPEMGEKQYISFCL*FIVCWSKQAEIICN GKHVTCLKVFLVALALC*KK**HWVSISF*DYIS RKISLFMLMI*LFCGNCFLKEVINIISYY*YFE HRWM*RIFI*KPSGFDFFC*MNNCALWNFCRSV YALLAFQLALL*RGINASVMCLSMYWLRILSQLS FLTV*VEF*TRACGHQASCQQFLKLLFHSCYST CISQLQH*VVKIHFWATSGNPCICLAFRQQSP* PSPTGLCLTSSSHLAV*RNGKREKERAIEAVDHI QFYLFIFNLFFSPSPPVSEIRTVGGMR*SGLIM L*FSFLSGVECSIPTRRIISYRLVLFRFCIYPF Y*NIY*VPCIFVTNLLKKNKTM*NIKIKRH**

Frame 1

AVSPPARRRAWLLVAIRKQQPFHLSFLHSGICS RAKGGRVLKEGLMSSSFSNSCKLCVG*NQTKPR AQGWEHAGDGLPAGTTALRLGAAVCVSGKGRYFK ACLSRRGGFSKPRQLRGVCGFDPVTQSFSMSCG LSGGQTSKATKNERP*RSSQVL*L*PYHHWRWL RRSGSC*GGSPIWQEGDGPGLCHSHPSWN*MGSR RNMCECGLHT*KTDASSSFVRTSPARLSKLWME SRGDS*A*LGQNDRSCTESHWLFELGLPSSSAG EKSRL*ECLWAIYWSSQD*GNK**RQRKNLFSRE ISHCHW*KTTLLGHPW*QRILHQQ**SFLLALL PG*DPGCWSILCRFGVRWISCWYWFRRHCYG*V HSS*RI*PGHGQQNW*THGRTWHQVYKTVRTN*S *TN*SRDTRPTQSSSSVHQ**GNH*RRI*YGDA GNRKRCLHKKNWLRNRRGEDK*KDWKNTCHR*R TDQCALHLCHWRYIGG*GGAHPSCNPGRKIAGSE ALCRFHCQV*L*KCSNHCIYSFGIWCLWPF*GE SCGEVWGRKY*GLP*LLLAIGMDDSVKR*QQML CKNNL*Y*RQ*TCCGLSRTGSKCWRSYTRLCSCA QMWTDQKAAGQHNWNPPCLCRGIHNIVCDQALW GKHPPGWLLRLSPSVDAVAKTANHWLVSVPKSK AKFSRGFLGSWHLRVLCLPPPKAPLDLLDRSW*I EGRQHHTGVTDRLEADIWQGIEGMHP*SHQSQA HVVGGDGTTVKSVLA*PFLVDFLILVVKFSRVE FFSFFSMVLMILEMKNVSS*FLSKSKSWLEYPCK VSCCMEGIVWLPWRLCRLVPGKRTVLQLKWTVL Y*PAQQFLLSYIPKTSTSAINSSQICPCVLHDG *LLF*GLFRKGNGYLASHCLAFGSIV*FSPLFVM EADIHQKWGRNSTYLSVFSLLCAGLSKLRSFAM ENT*LV*KFFW*L*LYAKKNNDIGYLFLSKTTL VGK*VFSCL*FSCFVVIAF*RKLLIS*VIINILN TGGCEGFSFKNQVVLTFSVE*TTVPCGIFAEVF MLC*HFNLHYYKEVLMPQLCVCQCTG*GFYLSC LF*LCRLSFEHVLVDIRPPASSS*SFFFIPATLP VFLSCSTEWSKYISGPPQGTHASAWHLGSRAPD RPPQGSASRPHLIWLCKEMGKGKRREQLRQLTI FSFIYLFLICFFLQVHQSLKLEQ*AV*DNQA*SC CDSLFLVEWNVLSPQEGLYLIDLSCSDSVFTHF IETYTKFHVFLLQIF*KKTKQCETLKLKGINN

Frame 2

QLARPLGAGRGFS*PLGNSNPFTSVFFTPAFAA ERKVVES*RRA*CLHHSQILVSSASGETRQSRE PRDGSTRGTACRRGRQHCAWVQQCASRGREDIL RRV*ADGEAFPNPGSFVACAVSTRSHKASACHVA YQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGS GGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGL GGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWK VEETVKHDWDRMIEAVQNHIGSLNWGYRVALRE KKVVYENAYGQFIGPHRIKATNNKGKEKIYSAE RFLIATGERPRYLGIPGDKEYCISSDDLFSLPYC PGKTLVVGASYVALECAGFLAGIGLDVTVMVRS ILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIK VEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVML AIGRDACTRKIGLETVGVKINEKTGKIPVTDEE QTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQ RLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEK AVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCY AKIICNTKDNERVVGFHVLGPNAGEVTQGFAAA LKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSG ASILQAGC*G*APVWMLLPRLQTTGSFPCPNPR RSFLEGSWALGTCVSCAYHRPRPPWISWIGVGE *KAGSITLGSLTDLKLTFGRASKGCIHEVTSLKP MW*AVMEQLSNQF*HDLSLWIFLFSLSSFLGLN FFLFSPWC**Y*R*KTLAVDFCPKASHG*SIHA RCLVAWKG*FGSLGGYVGLSRERELSCS*NGLFF TDLLSSFFSHIFPKQVHLRSTLAKFAPVCYMMD DYYFKVCLGREMATWPAIAWHLVV*YDSHHYLS WRQTYTRNGGETVHIFLSLVYCVLV*AS*DHLQW KTRNLFKSFSGSFSFMLKKIMTLGIYFFLRLH* *ENKSFHAYDLAVLW*LLFKGSY*YHKLLLIF* TQVDVKDFHLKTKWF*LFLLNEQLCLVEFLQKCL CFVSISTCIIIKRY*CLSYVFVNVLAEDSISAV FSNCVG*VLNTCLWTSGLLPAVLEASFSFLLLY LYFSVAALSGQNTFLGHLREPMHLPGI*AAEPLT VPHRALPHVLISFGCVKKWEKGKGESN*GS*PY SVLFIYF*FVFFSKSTSL*N*NSRRYEIIRPNH VVILFS*WSGMFYPHKKDYIL*TCLVQILYLPIL LKHILSSMYFCYKSSEKKQNNVKH*N*KALII

Sequence NM_003330

GGCAGTTAGCCCGCCCGCTCGGCGCAGGGCGTGGCTTCTCGTAGCCATTAGGAAACAGCAACCCTTTCACCTCAGTTTTCTTCACTCCGGCATTTGCAGC AGAGCGAAAGGTGGTCGAGTCCTGAAGGAGGGCCTGATGTCTTCATCATTCTCAAATTCTTGTAAGCTCTGCGTCGGGTGAAACCAGACAAAGCCGCGAG CCCAGGGATGGGAGCACGCGGGGGACGGCCTGCCGGCGGGGACGACAGCATTGCGCCTGGGTGCAGCAGTGTGCGTCTCGGGGAAGGGAAGATATTTTAA GGCGTGTCTGAGCAGACGGGGAGGCTTTTCCAAACCCAGGCAGCTTCGTGGCGTGTGCGGTTTCGACCCGGTCACACAAAGCTTCAGCATGTCATGTGAG GACGGTCGGGCCCTGGAAGGAACGCTCTCGGAATTGGCCGCGGAAACCGATCTGCCCGTTGTGTTTGTGAAACAGAGAAAGATAGGCGGCCATGGTCCAA CCTTGAAGGCTTATCAGGAGGGCAGACTTCAAAAGCTACTAAAAATGAACGGCCCTGAAGATCTTCCCAAGTCCTATGACTATGACCTTATCATCATTGG AGGTGGCTCAGGAGGTCTGGCAGCTGCTAAGGAGGCAGCCCAATATGGCAAGAAGGTGATGGTCCTGGACTTTGTCACTCCCACCCCTCTTGGAACTAGA TGGGGTCTCGGAGGAACATGTGTGAATGTGGGTTGCATACCTAAAAAACTGATGCATCAAGCAGCTTTGTTAGGACAAGCCCTGCAAGACTCTCGAAATT ATGGATGGAAAGTCGAGGAGACAGTTAAGCATGATTGGGACAGAATGATAGAAGCTGTACAGAATCACATTGGCTCTTTGAATTGGGGCTACCGAGTAGC TCTGCGGGAGAAAAAAGTCGTCTATGAGAATGCTTATGGGCAATTTATTGGTCCTCACAGGATTAAGGCAACAAATAATAAAGGCAAAGAAAAAATTTAT TCAGCAGAGAGATTTCTCATTGCCACTGGTGAAAGACCACGTTACTTGGGCATCCCTGGTGACAAAGAATACTGCATCAGCAGTGATGATCTTTTCTCCT TGCCTTACTGCCCGGGTAAGACCCTGGTTGTTGGAGCATCCTATGTCGCTTTGGAGTGCGCTGGATTTCTTGCTGGTATTGGTTTAGACGTCACTGTTAT GGTTAGGTCCATTCTTCTTAGAGGATTTGACCAGGACATGGCCAACAAAATTGGTGAACACATGGAAGAACATGGCATCAAGTTTATAAGACAGTTCGTA CCAATTAAAGTTGAACAAATTGAAGCAGGGACACCAGGCCGACTCAGAGTAGTAGCTCAGTCCACCAATAGTGAGGAAATCATTGAAGGAGAATATAATA CGGTGATGCTGGCAATAGGAAGAGATGCTTGCACAAGAAAAATTGGCTTAGAAACCGTAGGGGTGAAGATAAATGAAAAGACTGGAAAAATACCTGTCAC AGATGAAGAACAGACCAATGTGCCTTACATCTATGCCATTGGCGATATATTGGAGGATAAGGTGGAGCTCACCCCAGTTGCAATCCAGGCAGGAAGATTG CTGGCTCAGAGGCTCTATGCAGGTTCCACTGTCAAGTGTGACTATGAAAATGTTCCAACCACTGTATTTACTCCTTTGGAATATGGTGCTTGTGGCCTTT CTGAGGAGAAAGCTGTGGAGAAGTTTGGGGAAGAAAATATTGAGGTTTACCATAGTTACTTTTGGCCATTGGAATGGACGATTCCGTCAAGAGATAACAA CAAATGTTATGCAAAAATAATCTGTAATACTAAAGACAATGAACGTGTTGTGGGCTTTCACGTACTGGGTCCAAATGCTGGAGAAGTTACACAAGGCTTT GCAGCTGCGCTCAAATGTGGACTGACCAAAAAGCAGCTGGACAGCACAATTGGAATCCACCCTGTCTGTGCAGAGGTATTCACAACATTGTCTGTGACCA AGCGCTCTGGGGCAAGCATCCTCCAGGCTGGCTGCTGAGGTTAAGCCCCAGTGTGGATGCTGTTGCCAAGACTGCAAACCACTGGCTCGTTTCCGTGCCC AAATCCAAGGCGAAGTTTTCTAGAGGGTTCTTGGGCTCTTGGCACCTGCGTGTCCTGTGCTTACCACCGCCCAAGGCCCCCTTGGATCTCTTGGATAGGA GTTGGTGAATAGAAGGCAGGCAGCATCACACTGGGGTCACTGACAGACTTGAAGCTGACATTTGGCAGGGCATCGAAGGGATGCATCCATGAAGTCACCA GTCTCAAGCCCATGTGGTAGGCGGTGATGGAACAACTGTCAAATCAGTTTTAGCATGACCTTTCCTTGTGGATTTTCTTATTCTCGTTGTCAAGTTTTCT AGGGTTGAATTTTTTTCTTTTTTCTCCATGGTGTTAATGATATTAGAGATGAAAAACGTTAGCAGTTGATTTTTGTCCAAAAGCAAGTCATGGCTAGAGT ATCCATGCAAGGTGTCTTGTTGCATGGAAGGGATAGTTTGGCTCCCTTGGAGGCTATGTAGGCTTGTCCCGGGAAAGAGAACTGTCCTGCAGCTGAAATG GACTGTTCTTTACTGACCTGCTCAGCAGTTTCTTCTCTCATATATTCCCAAAACAAGTACATCTGCGATCAACTCTAGCCAAATTTGCCCCTGTGTGCTA CATGATGGATGATTATTATTTTAAGGTCTGTTTAGGAAGGGAAATGGCTACTTGGCCAGCCATTGCCTGGCATTTGGTAGTATAGTATGATTCTCACCAT TATTTGTCATGGAGGCAGACATACACCAGAAATGGGGGAGAAACAGTACATATCTTTCTGTCTTTAGTTTATTGTGTGCTGGTCTAAGCAAGCTGAGATC ATTTGCAATGGAAAACACGTAACTTGTTTAAAAGTTTTTCTGGTAGCTTTAGCTTTATGCTAAAAAAAATAATGACATTGGGTATCTATTTCTTTCTAAG ACTACATTAGTAGGAAAATAAGTCTTTTCATGCTTATGATTTAGCTGTTTTGTGGTAATTGCTTTTTAAAGGAAGTTATTAATATCATAAGTTATTATTA ATATTTTGAACACAGGTGGATGTGAAGGATTTTCATTTAAAAACCAAGTGGTTTTGACTTTTTCTGTTGAATGAACAACTGTGCCTTGTGGAATTTTTGC AGAAGTGTTTATGCTTTGTTAGCATTTCAACTTGCATTATTATAAAGAGGTATTAATGCCTCAGTTATGTGTTTGTCAATGTACTGGCTGAGGATTCTAT CTCAGCTGTCTTTTCTAACTGTGTAGGTTGAGTTTTGAACACGTGCTTGTGGACATCAGGCCTCCTGCCAGCAGTTCTTGAAGCTTCTTTTTCATTCCTG CTACTCTACCTGTATTTCTCAGTTGCAGCACTGAGTGGTCAAAATACATTTCTGGGCCACCTCAGGGAACCCATGCATCTGCCTGGCATTTAGGCAGCAG AGCCCCTGACCGTCCCCCACAGGGCTCTGCCTCACGTCCTCATCTCATTTGGCTGTGTAAAGAAATGGGAAAAGGGAAAAGGAGAGAGCAATTGAGGCAG TTGACCATATTCAGTTTTATTTATTTATTTTTAATTTGTTTTTTTCTCCAAGTCCACCAGTCTCTGAAATTAGAACAGTAGGCGGTATGAGATAATCAGG CCTAATCATGTTGTGATTCTCTTTTCTTAGTGGAGTGGAATGTTCTATCCCCACAAGAAGGATTATATCTTATAGACTTGTCTTGTTCAGATTCTGTATT TACCCATTTTATTGAAACATATACTAAGTTCCATGTATTTTTGTTACAAATCTTCTGAAAAAAAACAAAACAATGTGAAACATTAAAATTAAAAGGCATT AATAATA

refseq_TXNRD1.F2 (forward primer)
refseq_TXNRD1.R2 (reverse primer)
Single exon skipping

Frame 0

GS*PARSAQGVASRSH*ETATLSPQFSSLRHLQ QSERWSSPEGGPDVFIILKFL*ALRRVKPDKAAS PGMGARGGRPAGGDDSIAPGCSSVRLGEGKIF* GVSEQTGRLFQTQAASWRVRFRPGHTKLQHVM* GRSGPGRNALGIGRGNRSARCVCETEKDRRPWSN LEGLSGGQTSKATKNERP*RSSQVL*L*PYHHW RWLRRSGSC*GGSPIWQEGDGPGLCHSHPSWN* MGSRRNMCECGLHT*KTDASSSFVRTSPARLSKL WMESRGDS*A*LGQNDRSCTESHWLFELGLPSS SAGEKSRL*ECLWAIYWSSQD*GNK**RQRKNL FSREISHCHW*KTTLLGHPW*QRILHQQ**SFLL ALLPG*DPGCWSILCRFGVRWISCWYWFRRHCY G*VHSS*RI*PGHGQQNW*THGRTWHQVYKTVR TN*S*TN*SRDTRPTQSSSSVHQ**GNH*RRI*Y GDAGNRKRCLHKKNWLRNRRGEDK*KDWKNTCH R*RTDQCALHLCHWRYIGG*GGAHPSCNPGRKI AGSEALCRFHCQV*L*KCSNHCIYSFGIWCLWPF *GESCGEVWGRKY*GLP*LLLAIGMDDSVKR*Q QMLCKNNL*Y*RQ*TCCGLSRTGSKCWRSYTRL CSCAQMWTDQKAAGQHNWNPPCLCRGIHNIVCDQ ALWGKHPPGWLLRLSPSVDAVAKTANHWLVSVP KSKAKFSRGFLGSWHLRVLCLPPPKAPLDLLDR SW*IEGRQHHTGVTDRLEADIWQGIEGMHP*SHQ SQAHVVGGDGTTVKSVLA*PFLVDFLILVVKFS RVEFFSFFSMVLMILEMKNVSS*FLSKSKSWLE YPCKVSCCMEGIVWLPWRLCRLVPGKRTVLQLKW TVLY*PAQQFLLSYIPKTSTSAINSSQICPCVL HDG*LLF*GLFRKGNGYLASHCLAFGSIV*FSP LFVMEADIHQKWGRNSTYLSVFSLLCAGLSKLRS FAMENT*LV*KFFW*L*LYAKKNNDIGYLFLSK TTLVGK*VFSCL*FSCFVVIAF*RKLLIS*VII NILNTGGCEGFSFKNQVVLTFSVE*TTVPCGIFA EVFMLC*HFNLHYYKEVLMPQLCVCQCTG*GFY LSCLF*LCRLSFEHVLVDIRPPASSS*SFFFIP ATLPVFLSCSTEWSKYISGPPQGTHASAWHLGSR APDRPPQGSASRPHLIWLCKEMGKGKRREQLRQ LTIFSFIYLFLICFFLQVHQSLKLEQ*AV*DNQ A*SCCDSLFLVEWNVLSPQEGLYLIDLSCSDSVF THFIETYTKFHVFLLQIF*KKTKQCETLKLKGI NN

Frame 1

AVSPPARRRAWLLVAIRKQQPFHLSFLHSGICS RAKGGRVLKEGLMSSSFSNSCKLCVG*NQTKPR AQGWEHAGDGLPAGTTALRLGAAVCVSGKGRYFK ACLSRRGGFSKPRQLRGVCGFDPVTQSFSMSCE DGRALEGTLSELAAETDLPVVFVKQRKIGGHGP TLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIG GGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTR WGLGGTCVNVGCIPKKLMHQAALLGQALQDSRN YGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVA LREKKVVYENAYGQFIGPHRIKATNNKGKEKIY SAERFLIATGERPRYLGIPGDKEYCISSDDLFS LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVM VRSILLRGFDQDMANKIGEHMEEHGIKFIRQFV PIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYN TVMLAIGRDACTRKIGLETVGVKINEKTGKIPVT DEEQTNVPYIYAIGDILEDKVELTPVAIQAGRL LAQRLYAGSTVKCDYENVPTTVFTPLEYGACGL SEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNN KCYAKIICNTKDNERVVGFHVLGPNAGEVTQGF AAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT KRSGASILQAGC*G*APVWMLLPRLQTTGSFPCP NPRRSFLEGSWALGTCVSCAYHRPRPPWISWIG VGE*KAGSITLGSLTDLKLTFGRASKGCIHEVT SLKPMW*AVMEQLSNQF*HDLSLWIFLFSLSSFL GLNFFLFSPWC**Y*R*KTLAVDFCPKASHG*S IHARCLVAWKG*FGSLGGYVGLSRERELSCS*N GLFFTDLLSSFFSHIFPKQVHLRSTLAKFAPVCY MMDDYYFKVCLGREMATWPAIAWHLVV*YDSHH YLSWRQTYTRNGGETVHIFLSLVYCVLV*AS*D HLQWKTRNLFKSFSGSFSFMLKKIMTLGIYFFLR LH**ENKSFHAYDLAVLW*LLFKGSY*YHKLLL IF*TQVDVKDFHLKTKWF*LFLLNEQLCLVEFL QKCLCFVSISTCIIIKRY*CLSYVFVNVLAEDSI SAVFSNCVG*VLNTCLWTSGLLPAVLEASFSFL LLYLYFSVAALSGQNTFLGHLREPMHLPGI*AA EPLTVPHRALPHVLISFGCVKKWEKGKGESN*GS *PYSVLFIYF*FVFFSKSTSL*N*NSRRYEIIR PNHVVILFS*WSGMFYPHKKDYIL*TCLVQILY LPILLKHILSSMYFCYKSSEKKQNNVKH*N*KAL II

Frame 2

QLARPLGAGRGFS*PLGNSNPFTSVFFTPAFAA ERKVVES*RRA*CLHHSQILVSSASGETRQSRE PRDGSTRGTACRRGRQHCAWVQQCASRGREDIL RRV*ADGEAFPNPGSFVACAVSTRSHKASACHVR TVGPWKERSRNWPRKPICPLCL*NRER*AAMVQ P*RLIRRADFKSY*K*TALKIFPSPMTMTLSSL EVAQEVWQLLRRQPNMARR*WSWTLSLPPLLELD GVSEEHV*MWVAYLKN*CIKQLC*DKPCKTLEI MDGKSRRQLSMIGTE**KLYRITLAL*IGATE* LCGRKKSSMRMLMGNLLVLTGLRQQIIKAKKKFI QQRDFSLPLVKDHVTWASLVTKNTASAVMIFSP CLTARVRPWLLEHPMSLWSALDFLLVLV*TSLL WLGPFFLEDLTRTWPTKLVNTWKNMASSL*DSSY QLKLNKLKQGHQADSE**LSPPIVRKSLKENII R*CWQ*EEMLAQEKLA*KP*G*R*MKRLEKYLS QMKNRPMCLTSMPLAIYWRIRWSSPQLQSRQEDC WLRGSMQVPLSSVTMKMFQPLYLLLWNMVLVAF LRRKLWRSLGKKILRFTIVTFGHWNGRFRQEIT TNVMQK*SVILKTMNVLWAFTYWVQMLEKLHKAL QLRSNVD*PKSSWTAQLESTLSVQRYSQHCL*P SALGQASSRLAAEVKPQCGCCCQDCKPLARFRA QIQGEVF*RVLGLLAPACPVLTTAQGPLGSLG*E LVNRRQAASHWGH*QT*S*HLAGHRRDASMKSP VSSPCGRR*WNNCQISFSMTFPCGFSYSRCQVF *G*IFFFFLHGVNDIRDEKR*QLIFVQKQVMARV SMQGVLLHGRDSLAPLEAM*ACPGKENCPAAEM DCSLLTCSAVSSLIYSQNKYICDQL*PNLPLCA T*WMIIILRSV*EGKWLLGQPLPGIW*YSMILTI ICHGGRHTPEMGEKQYISFCL*FIVCWSKQAEI ICNGKHVTCLKVFLVALALC*KK**HWVSISF* DYISRKISLFMLMI*LFCGNCFLKEVINIISYY* YFEHRWM*RIFI*KPSGFDFFC*MNNCALWNFC RSVYALLAFQLALL*RGINASVMCLSMYWLRIL SQLSFLTV*VEF*TRACGHQASCQQFLKLLFHSC YSTCISQLQH*VVKIHFWATSGNPCICLAFRQQ SP*PSPTGLCLTSSSHLAV*RNGKREKERAIEA VDHIQFYLFIFNLFFSPSPPVSEIRTVGGMR*SG LIML*FSFLSGVECSIPTRRIISYRLVLFRFCI YPFY*NIY*VPCIFVTNLLKKNKTM*NIKIKRH **