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Sequences

Sequence NM_001005367

CCCAGCCAGACCCCGCGCCGCCCGCGCCCCGCTCGACTCCGGAGGCTCCCGCAGCCCCGGCGTCCGCCCCGCTGCCCCCTCCCCCGGGGGCCATGGGGGC
GCCCCCGGGCTACCGGCCCTCAGCTTGGGTGCATCTCCTCCACCAGCTGCCCCGCGCCGACTTCCAGCTCCGCCCGGTGCCCAGCGTTTTCGCGCCCCAA
GAGCAGGAATACCAGCAGGCCTTGTTGCTGGTGGCGGCCTTGGCGGGCCTGGGCTTGGGCCTGAGCCTCATTTTCATCGCTGTCTACCTCATCCGCTTCT
GCTGCTGCCGGCCCCCCGAGCCCCCCGGGTCCAAGATCCCCTCGCCCGGGGGAGGCTGCGTCACCTGGAGCTGCATTGTCGCCCTTCTCGCCGGCTGCAC
TGGCATTGGCATCGGTTTCTATGGCAACAGTGAGACCAGTGATGGGGTGTCCCAGCTCAGCTCTGCGCTGCTGCACGCCAACCACACACTCAGCACCATT
GACCACCTGGTGTTGGAGACGGTGGAGAGGCTGGGCGAGGCGGTGAGGACAGAGCTGACCACCCTGGAGGAGGTGCTCGAGCCGCGCACGGAGCTGGTGG
CTGCCGCCCGAGGGGCTCGACGGCAGGCGGAGGCTGCGGCCCAGCAGCTGCAGGGGCTGGCCTTCTGGCAGGGAGTGCCCCTGAGCCCCCTGCAGGTGGC
TGAAAATGTGTCCTTTGTGGAGGAGTACAGGTGGCTGGCCTACGTCCTCCTGCTGCTCCTGGAGCTGCTGGTCTGCCTCTTCACCCTCCTGGGCCTGGCG
AAGCAGAGCAAGTGGCTGGTGATCGTGATGACAGTCATGAGTCTCCTGGTTCTCGTCCTGAGCTGGGGCTCCATGGGCCTGGAGGCAGCCACGGCCGTGG
GCCTCAGTGACTTCTGCTCCAATCCAGACCCTTATGTTCTGAACCTGACCCAGGAGGAGACAGGGCTCAGCTCAGACATCCTGAGCTATTATCTCCTCTG
CAACCGGGCCGTCTCCAACCCCTTCCAACAGAGGCTGACTCTGTCCCAGCGAGCTCTGGCCAACATCCACTCCCAGCTGCTGGGCCTGGAGCGAGAAGCT
GTGCCTCAGTTCCCTTCAGCGCAGAAGCCTCTGCTGTCCTTGGAGGAGACTCTGAATGTGACAGAAGGAAATTTCCACCAGTTGGTGGCACTGCTACACT
GCCGCAGCCTGCACAAGGACTATGGTGCAGCCCTGCGGGGCCTGTGCGAAGACGCCCTGGAAGGCCTGCTCTTCCTGCTACTCTTCTCCCTGCTGTCTGC
AGGAGCGCTGGCCACTGCCCTCTGCAGCCTGCCCCGAGCCTGGGCCCTCTTCCCACCCAGGAATCCAAGCGCTTTGTGCAGTGGCAGTCGTCTATCTGAG
CCCCTCCTCCCGGCTGGACTGGAGCCTGGCTCCCCTCTTCGTTCCTTCCCTGGCTGCCGGAGGAGACCCCACTAACCCAGCCTGCCTGGGCTCTGACCAC
TAACACTCTTGGCCATGGACAGCCTGCACAGGACCGCCTCCCTGCTCTTGGCCACTGTGCTCCCATTTCTGTCCTTGGCCTTGGGAGTAGCTGAGGGGGC
AGACTAGGGAGTAGGGCTGGCAGGGGAGGGGGCAGACAGCCTCGCCTCGCACCCTTCATCCCTGGCTGCCGGTCCCATCCTTGGAGGGACTAAGCTGGGG
GTGGGGGACATGAGTCCCCCTGCTGCCCCTGCCACATCCCAGTGGGCTCTGACCCCCTGATCTCAACTCGTGGCACTAACTTGGAAAAGGGTTGATTTAA
AATAAAAGGGAAGACTATTTTACAAGCAGCTGGGTCCTCCTTATTTCTCCTCTCCCTTGATTCGGCCTCCTGGCCAGGGCTGGGACATCCTCCCTGCTGT
CCTCTCTCCCCCGGCCTCCCAGCTGCCAGGAATTTCTGCGCCTGTCCAGGCTCAGCAAGGGGTCCAAAGACATTGTTCTTTAAAAAAAAAAAAAAAAAA
  • refseq_TTYH1.F1 (forward primer)
  • refseq_TTYH1.R1 (reverse primer)
  • Single exon skipping

Frame 0

PSQTPRRPRPARLRRLPQPRRPPRCPLPRGPWG
RPRATGPQLGCISSTSCPAPTSSSARCPAFSRPK
SRNTSRPCCWWRPWRAWAWA*ASFSSLSTSSAS
AAAGPPSPPGPRSPRPGEAASPGAALSPFSPAA
LALASVSMATVRPVMGCPSSALRCCTPTTHSAPL
TTWCWRRWRGWARR*GQS*PPWRRCSSRARSWW
LPPEGLDGRRRLRPSSCRGWPSGRECP*APCRW
LKMCPLWRSTGGWPTSSCCSWSCWSASSPSWAWR
SRASGW*S**QS*VSWFSS*AGAPWAWRQPRPW
ASVTSAPIQTLMF*T*PRRRQGSAQTS*AIISS
ATGPSPTPSNRG*LCPSELWPTSTPSCWAWSEKL
CLSSLQRRSLCCPWRRL*M*QKEISTSWWHCYT
AAACTRTMVQPCGACAKTPWKACSSCYSSPCCL
QERWPLPSAACPEPGPSSHPGIQALCAVAVVYLS
PSSRLDWSLAPLFVPSLAAGGDPTNPACLGSDH
*HSWPWTACTGPPPCSWPLCSHFCPWPWE*LRG
QTRE*GWQGRGQTASPRTLHPWLPVPSLEGLSWG
WGT*VPLLPLPHPSGL*PPDLNSWH*LGKGLI*
NKREDYFTSSWVLLISPLP*FGLLARAGTSSLL
SSLPRPPSCQEFLRLSRLSKGSKDIVL*KKKKK

Frame 1

PARPRAARAPLDSGGSRSPGVRPAAPSPGGHGG
APGLPALSLGASPPPAAPRRLPAPPGAQRFRAP
RAGIPAGLVAGGGLGGPGLGPEPHFHRCLPHPLL
LLPAPRAPRVQDPLARGRLRHLELHCRPSRRLH
WHWHRFLWQQ*DQ*WGVPAQLCAAARQPHTQHH
*PPGVGDGGEAGRGGEDRADHPGGGARAAHGAGG
CRPRGSTAGGGCGPAAAGAGLLAGSAPEPPAGG
*KCVLCGGVQVAGLRPPAAPGAAGLPLHPPGPG
EAEQVAGDRDDSHESPGSRPELGLHGPGGSHGRG
PQ*LLLQSRPLCSEPDPGGDRAQLRHPELLSPL
QPGRLQPLPTEADSVPASSGQHPLPAAGPGARS
CASVPFSAEASAVLGGDSECDRRKFPPVGGTATL
PQPAQGLWCSPAGPVRRRPGRPALPATLLPAVC
RSAGHCPLQPAPSLGPLPTQESKRFVQWQSSI*
APPPGWTGAWLPSSFLPWLPEETPLTQPAWALTT
NTLGHGQPAQDRLPALGHCAPISVLGLGSS*GG
RLGSRAGRGGGRQPRLAPFIPGCRSHPWRD*AG
GGGHESPCCPCHIPVGSDPLISTRGTNLEKG*FK
IKGKTILQAAGSSLFLLSLDSASWPGLGHPPCC
PLSPGLPAARNFCACPGSARGPKTLFFKKKKKK

Frame 2

QPDPAPPAPRSTPEAPAAPASAPLPPPPGAMGA
PPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQ
EQEYQQALLLVAALAGLGLGLSLIFIAVYLIRF
CCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCT
GIGIGFYGNSETSDGVSQLSSALLHANHTLSTI
DHLVLETVERLGEAVRTELTTLEEVLEPRTELV
AAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVA
ENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLA
KQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAV
GLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLC
NRAVSNPFQQRLTLSQRALANIHSQLLGLEREA
VPQFPSAQKPLLSLEETLNVTEGNFHQLVALLH
CRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSA
GALATALCSLPRAWALFPPRNPSALCSGSRLSE
PLLPAGLEPGSPLRSFPGCRRRPH*PSLPGL*P
LTLLAMDSLHRTASLLLATVLPFLSLALGVAEGA
D*GVGLAGEGADSLASHPSSLAAGPILGGTKLG
VGDMSPPAAPATSQWALTP*SQLVALTWKRVDL
K*KGRLFYKQLGPPYFSSPLIRPPGQGWDILPAV
LSPPASQLPGISAPVQAQQGVQRHCSLKKKKK

Sequence NM_020659

CCCAGCCAGACCCCGCGCCGCCCGCGCCCCGCTCGACTCCGGAGGCTCCCGCAGCCCCGGCGTCCGCCCCGCTGCCCCCTCCCCCGGGGGCCATGGGGGC
GCCCCCGGGCTACCGGCCCTCAGCTTGGGTGCATCTCCTCCACCAGCTGCCCCGCGCCGACTTCCAGCTCCGCCCGGTGCCCAGCGTTTTCGCGCCCCAA
GAGCAGGAATACCAGCAGGCCTTGTTGCTGGTGGCGGCCTTGGCGGGCCTGGGCTTGGGCCTGAGCCTCATTTTCATCGCTGTCTACCTCATCCGCTTCT
GCTGCTGCCGGCCCCCCGAGCCCCCCGGGTCCAAGATCCCCTCGCCCGGGGGAGGCTGCGTCACCTGGAGCTGCATTGTCGCCCTTCTCGCCGGCTGCAC
TGGCATTGGCATCGGTTTCTATGGCAACAGTGAGACCAGTGATGGGGTGTCCCAGCTCAGCTCTGCGCTGCTGCACGCCAACCACACACTCAGCACCATT
GACCACCTGGTGTTGGAGACGGTGGAGAGGCTGGGCGAGGCGGTGAGGACAGAGCTGACCACCCTGGAGGAGGTGCTCGAGCCGCGCACGGAGCTGGTGG
CTGCCGCCCGAGGGGCTCGACGGCAGGCGGAGGCTGCGGCCCAGCAGCTGCAGGGGCTGGCCTTCTGGCAGGGAGTGCCCCTGAGCCCCCTGCAGGTGGC
TGAAAATGTGTCCTTTGTGGAGGAGTACAGGTGGCTGGCCTACGTCCTCCTGCTGCTCCTGGAGCTGCTGGTCTGCCTCTTCACCCTCCTGGGCCTGGCG
AAGCAGAGCAAGTGGCTGGTGATCGTGATGACAGTCATGAGTCTCCTGGTTCTCGTCCTGAGCTGGGGCTCCATGGGCCTGGAGGCAGCCACGGCCGTGG
GCCTCAGTGACTTCTGCTCCAATCCAGACCCTTATGTTCTGAACCTGACCCAGGAGGAGACAGGGCTCAGCTCAGACATCCTGAGCTATTATCTCCTCTG
CAACCGGGCCGTCTCCAACCCCTTCCAACAGAGGCTGACTCTGTCCCAGCGAGCTCTGGCCAACATCCACTCCCAGCTGCTGGGCCTGGAGCGAGAAGCT
GTGCCTCAGTTCCCTTCAGCGCAGAAGCCTCTGCTGTCCTTGGAGGAGACTCTGAATGTGACAGAAGGAAATTTCCACCAGTTGGTGGCACTGCTACACT
GCCGCAGCCTGCACAAGGACTATGGTGCAGCCCTGCGGGGCCTGTGCGAAGACGCCCTGGAAGGCCTGCTCTTCCTGCTACTCTTCTCCCTGCTGTCTGC
AGGAGCGCTGGCCACTGCCCTCTGCAGCCTGCCCCGAGCCTGGGCCCTCTTCCCACCCAGTGACGACTACGATGACACAGACGATGACGACCCTTTCAAC
CCTCAGGAATCCAAGCGCTTTGTGCAGTGGCAGTCGTCTATCTGAGCCCCTCCTCCCGGCTGGACTGGAGCCTGGCTCCCCTCTTCGTTCCTTCCCTGGC
TGCCGGAGGAGACCCCACTAACCCAGCCTGCCTGGGCTCTGACCACTAACACTCTTGGCCATGGACAGCCTGCACAGGACCGCCTCCCTGCTCTTGGCCA
CTGTGCTCCCATTTCTGTCCTTGGCCTTGGGAGTAGCTGAGGGGGCAGACTAGGGAGTAGGGCTGGCAGGGGAGGGGGCAGACAGCCTCGCCTCGCACCC
TTCATCCCTGGCTGCCGGTCCCATCCTTGGAGGGACTAAGCTGGGGGTGGGGGACATGAGTCCCCCTGCTGCCCCTGCCACATCCCAGTGGGCTCTGACC
CCCTGATCTCAACTCGTGGCACTAACTTGGAAAAGGGTTGATTTAAAATAAAAGGGAAGACTATTTTACAAGCAGCTGGGTCCTCCTTATTTCTCCTCTC
CCTTGATTCGGCCTCCTGGCCAGGGCTGGGACATCCTCCCTGCTGTCCTCTCTCCCCCGGCCTCCCAGCTGCCAGGAATTTCTGCGCCTGTCCAGGCTCA
GCAAGGGGTCCAAAGACATTGTTCTTTAAAAAAAAAAAAAAAAAA
  • refseq_TTYH1.F1 (forward primer)
  • refseq_TTYH1.R1 (reverse primer)
  • Single exon skipping

Frame 0

PSQTPRRPRPARLRRLPQPRRPPRCPLPRGPWG
RPRATGPQLGCISSTSCPAPTSSSARCPAFSRPK
SRNTSRPCCWWRPWRAWAWA*ASFSSLSTSSAS
AAAGPPSPPGPRSPRPGEAASPGAALSPFSPAA
LALASVSMATVRPVMGCPSSALRCCTPTTHSAPL
TTWCWRRWRGWARR*GQS*PPWRRCSSRARSWW
LPPEGLDGRRRLRPSSCRGWPSGRECP*APCRW
LKMCPLWRSTGGWPTSSCCSWSCWSASSPSWAWR
SRASGW*S**QS*VSWFSS*AGAPWAWRQPRPW
ASVTSAPIQTLMF*T*PRRRQGSAQTS*AIISS
ATGPSPTPSNRG*LCPSELWPTSTPSCWAWSEKL
CLSSLQRRSLCCPWRRL*M*QKEISTSWWHCYT
AAACTRTMVQPCGACAKTPWKACSSCYSSPCCL
QERWPLPSAACPEPGPSSHPVTTTMTQTMTTLST
LRNPSALCSGSRLSEPLLPAGLEPGSPLRSFPG
CRRRPH*PSLPGL*PLTLLAMDSLHRTASLLLA
TVLPFLSLALGVAEGAD*GVGLAGEGADSLASHP
SSLAAGPILGGTKLGVGDMSPPAAPATSQWALT
P*SQLVALTWKRVDLK*KGRLFYKQLGPPYFSS
PLIRPPGQGWDILPAVLSPPASQLPGISAPVQAQ
QGVQRHCSLKKKKK

Frame 1

PARPRAARAPLDSGGSRSPGVRPAAPSPGGHGG
APGLPALSLGASPPPAAPRRLPAPPGAQRFRAP
RAGIPAGLVAGGGLGGPGLGPEPHFHRCLPHPLL
LLPAPRAPRVQDPLARGRLRHLELHCRPSRRLH
WHWHRFLWQQ*DQ*WGVPAQLCAAARQPHTQHH
*PPGVGDGGEAGRGGEDRADHPGGGARAAHGAGG
CRPRGSTAGGGCGPAAAGAGLLAGSAPEPPAGG
*KCVLCGGVQVAGLRPPAAPGAAGLPLHPPGPG
EAEQVAGDRDDSHESPGSRPELGLHGPGGSHGRG
PQ*LLLQSRPLCSEPDPGGDRAQLRHPELLSPL
QPGRLQPLPTEADSVPASSGQHPLPAAGPGARS
CASVPFSAEASAVLGGDSECDRRKFPPVGGTATL
PQPAQGLWCSPAGPVRRRPGRPALPATLLPAVC
RSAGHCPLQPAPSLGPLPTQ*RLR*HRR*RPFQ
PSGIQALCAVAVVYLSPSSRLDWSLAPLFVPSLA
AGGDPTNPACLGSDH*HSWPWTACTGPPPCSWP
LCSHFCPWPWE*LRGQTRE*GWQGRGQTASPRT
LHPWLPVPSLEGLSWGWGT*VPLLPLPHPSGL*P
PDLNSWH*LGKGLI*NKREDYFTSSWVLLISPL
P*FGLLARAGTSSLLSSLPRPPSCQEFLRLSRL
SKGSKDIVL*KKKKK

Frame 2

QPDPAPPAPRSTPEAPAAPASAPLPPPPGAMGA
PPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQ
EQEYQQALLLVAALAGLGLGLSLIFIAVYLIRF
CCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCT
GIGIGFYGNSETSDGVSQLSSALLHANHTLSTI
DHLVLETVERLGEAVRTELTTLEEVLEPRTELV
AAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVA
ENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLA
KQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAV
GLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLC
NRAVSNPFQQRLTLSQRALANIHSQLLGLEREA
VPQFPSAQKPLLSLEETLNVTEGNFHQLVALLH
CRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSA
GALATALCSLPRAWALFPPSDDYDDTDDDDPFN
PQESKRFVQWQSSI*APPPGWTGAWLPSSFLPW
LPEETPLTQPAWALTTNTLGHGQPAQDRLPALGH
CAPISVLGLGSS*GGRLGSRAGRGGGRQPRLAP
FIPGCRSHPWRD*AGGGGHESPCCPCHIPVGSD
PLISTRGTNLEKG*FKIKGKTILQAAGSSLFLLS
LDSASWPGLGHPPCCPLSPGLPAARNFCACPGS
ARGPKTLFFKKKKKK

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