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Sequences

Sequence NM_199004

CCCCGCGTGTCTGCTAGGAGAGGGCGGGCAGCGCCGCGGCGCGCGCGATCCGGCTGACGCATCTGGCCCCGGTTCCCCAAGACCAGAGCGGGGCCGGGAG GGAGGGGGAAGAGGCGAGAGCGCGGAGGGCGCGCGTGCGCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCG AACCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGGGTCTTCAAGAAGTCGAGCCCTAACTGCAAGCTCACCGTGTACTTGGGC AAGCGGGACTTCGTAGATCACCTGGACAAAGTGGACCCTGTAGTGTTTGTGACCCTCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTGGATGTGCTGG GCTTGTCCTTCCGCAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGGTGCCCAACCCACCCCGGCCCCCCACCCGCCTGCAGGACCGGCTGCT GAGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCATACCCCAGAATCTTCCATGCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAG GCCTGCGGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAGCCACAAAAGGAACTCTGTGCGGCTGGTGATCCGAAAGGTGC AGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTTCAGCCGAAACCACACGCCACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGACAA GGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAACTCCACCAAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTAC GCCGACATCTGCCTCTTCAGCACCGCCCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGACCAGGTATCTCCCAGCTCCACATTCTGTAAGGTGT ACACCATAACCCCACTGCTCAGCGACAACCGGGAGAAGCGGGGTCTCGCCCTGGATGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAGCACCAT CGTGAAGGAGGGTGCCAACAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAGGTGAAGCTGGTGGTGTCTCGAGGCGGGGATGTCTCTGTGGAG CTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGACCACATCCCCCTCCCCAGACCCCAGTCAGCCGCTCCGGAGACAGATGTCCCTGTGGACACCAACC TCATTGAATTTGATACCAACTATGCCACAGATGATGACATTGTGTTTGAGGACTTTGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGACTATGATGA TCAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGGTGAGGGCAGGATTAAGATCCCCACTGTCAATGGGGGATTGTCCCA GCCCCTCTTCCCTTCCCCTCACCTGGAAGCTTCTTCAACCAATCCCTTCACACTCTCTCCCCCATCCCCCCAAGATACACACTGGACCCTCTCTTGCTGA ATGTGGGCATTAATTTTTTGACTGCAGCTCTGCTTCTCCAGCCCCGCCGTGGGTGGCAAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGACAGTGAAA AGAGGAGTGACAGGAGGGAAAGGGGGAGACAAAACTCCTACTCTCAACCTCACACCAACACCTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAAGAG GAGACCCTTTGGGGACAAGGCCGTTTCTTTGTTTCTGAGCATAAAGAAGAAAATAAATCTTTTACTAAGCATGA

refseq_ARRB2.F1 (forward primer)
refseq_ARRB2.R1 (reverse primer)
Single exon skipping

Frame 0

PRVSARRGRAAPRRARSG*RIWPRFPKTRAGPG GRGKRRERGGRACALARGGAGILAAGEEAASEPR TERAAGARTMGEKPGTRVFKKSSPNCKLTVYLG KRDFVDHLDKVDPVVFVTLTCAFRYGREDLDVL GLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLL RKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGK ACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKV QFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDK ELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQY ADICLFSTAQYKCPVAQLEQDDQVSPSSTFCKV YTITPLLSDNREKRGLALDGKLKHEDTNLASSTI VKEGANKEVLGILVSYRVKVKLVVSRGGDVSVE LPFVLMHPKPHDHIPLPRPQSAAPETDVPVDTN LIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDD QLC*EAGWEEGRGWGWER*GQD*DPHCQWGIVP APLPFPSPGSFFNQSLHTLSPIPPRYTLDPLLL NVGINFLTAALLLQPRRGWQAVFIPKFSGRGQ*K EE*QEGKGETKLLLSTSHQHLPLSLSLPPFLQE ETLWGQGRFFVSEHKEENKSFTKH

Frame 1

PACLLGEGGQRRGARDPADASGPGSPRPERGRE GGGRGESAEGARAHWRGEEQGSWQRARRLRASR EPSGRRARAPWGRNPGPGSSRSRALTASSPCTWA SGTS*ITWTKWTL*CL*PSPAPSAMAVKTWMCW ACPSAKTCSSPPTRPSPRCPTHPGPPPACRTGC *GSWASMPTPSSSPYPRIFHAPSHCSQAQRIQER PAA*TLRFEPSVLNH*KRKATKGTLCGW*SERC SSPRRNPAPSLQPKPHATSSCLTGPCTSRLPWT RSCTTMGSPSM*MSTSPTTPPRPSRRSKSL*DST PTSASSAPPSTSVLWLNSNKMTRYLPAPHSVRC TP*PHCSATTGRSGVSPWMGNSSTRTPTWLPAP S*RRVPTRRCWESWCPTGSR*SWWCLEAGMSLWS CLLFLCTPSPTTTSPSPDPSQPLRRQMSLWTPT SLNLIPTMPQMMTLCLRTLPGFG*RG*RMTTMM INSARKRGGKKGGDGVGRGEGRIKIPTVNGGLSQ PLFPSPHLEASSTNPFTLSPPSPQDTHWTLSC* MWALIF*LQLCFSSPAVGGKLCSYLNFLEGDSE KRSDRRERGRQNSYSQPHTNTSHYHSLCPHSFKR RPFGDKAVSLFLSIKKKINLLLSM

Frame 2

PRVC*ERAGSAAARAIRLTHLAPVPQDQSGAGR EGEEARARRARVRIGAGRSRDLGSGRGGCERAA NRAGGGRAHHGGETRDQGLQEVEP*LQAHRVLG QAGLRRSPGQSGPCSVCDPHLRLPLWP*RPGCAG LVLPQRPVHRHLPGLPPGAQPTPAPHPPAGPAA EEAGPACPPLLLHHTPESSMLRHTAARPRGYRK GLRRRL*DSSLLC*ITRREKPQKELCAAGDPKGA VRPGETRPPAFSRNHTPLPHV*PVPAPRGFPGQ GAVLPWGAPQCKCPRHQQLHQDRQEDQSLCETV RRHLPLQHRPVQVSCGSTRTR*PGISQLHIL*GV HHNPTAQRQPGEAGSRPGWETQARGHQPGFQHH REGGCQQGGAGNPGVLQGQGEAGGVSRRGCLCG AAFCSYAPQAPRPHPPPQTPVSRSGDRCPCGHQP H*I*YQLCHR**HCV*GLCPASAEGDEG*RL** STLLGSGVGRREGMGLGEVRAGLRSPLSMGDCP SPSSLPLTWKLLQPIPSHSLPHPPKIHTGPSLAE CGH*FFDCSSASPAPPWVASCVHT*IFWKGTVK RGVTGGKGGDKTPTLNLTPTPPIITLSAPIPSR GDPLGTRPFLCF*A*RRK*IFY*A*

Sequence NM_004313

CCCCGCGTGTCTGCTAGGAGAGGGCGGGCAGCGCCGCGGCGCGCGCGATCCGGCTGACGCATCTGGCCCCGGTTCCCCAAGACCAGAGCGGGGCCGGGAG GGAGGGGGAAGAGGCGAGAGCGCGGAGGGCGCGCGTGCGCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCG AACCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGGGTCTTCAAGAAGTCGAGCCCTAACTGCAAGCTCACCGTGTACTTGGGC AAGCGGGACTTCGTAGATCACCTGGACAAAGTGGACCCTGTAGATGGCGTGGTGCTTGTGGACCCTGACTACCTGAAGGACCGCAAAGTGTTTGTGACCC TCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTGGATGTGCTGGGCTTGTCCTTCCGCAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGGT GCCCAACCCACCCCGGCCCCCCACCCGCCTGCAGGACCGGCTGCTGAGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCATACCCCAGAATCTT CCATGCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAGGCCTGCGGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGA AAAGCCACAAAAGGAACTCTGTGCGGCTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTTCAGCCGAAACCACACGCCACTT CCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGACAAGGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAAC TCCACCAAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTCTTCAGCACCGCCCAGTACAAGTGTCCTGTGGCTCAACTCG AACAAGATGACCAGGTATCTCCCAGCTCCACATTCTGTAAGGTGTACACCATAACCCCACTGCTCAGCGACAACCGGGAGAAGCGGGGTCTCGCCCTGGA TGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAGCACCATCGTGAAGGAGGGTGCCAACAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTC AAGGTGAAGCTGGTGGTGTCTCGAGGCGGGGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGACCACATCCCCCTCCCCAGAC CCCAGTCAGCCGCTCCGGAGACAGATGTCCCTGTGGACACCAACCTCATTGAATTTGATACCAACTATGCCACAGATGATGACATTGTGTTTGAGGACTT TGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGACTATGATGATCAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGG TGAGGGCAGGATTAAGATCCCCACTGTCAATGGGGGATTGTCCCAGCCCCTCTTCCCTTCCCCTCACCTGGAAGCTTCTTCAACCAATCCCTTCACACTC TCTCCCCCATCCCCCCAAGATACACACTGGACCCTCTCTTGCTGAATGTGGGCATTAATTTTTTGACTGCAGCTCTGCTTCTCCAGCCCCGCCGTGGGTG GCAAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGACAGTGAAAAGAGGAGTGACAGGAGGGAAAGGGGGAGACAAAACTCCTACTCTCAACCTCACAC CAACACCTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAAGAGGAGACCCTTTGGGGACAAGGCCGTTTCTTTGTTTCTGAGCATAAAGAAGAAAATA AATCTTTTACTAAGCATGA

refseq_ARRB2.F1 (forward primer)
refseq_ARRB2.R1 (reverse primer)
Single exon skipping

Frame 0

PRVSARRGRAAPRRARSG*RIWPRFPKTRAGPG GRGKRRERGGRACALARGGAGILAAGEEAASEPR TERAAGARTMGEKPGTRVFKKSSPNCKLTVYLG KRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVT LTCAFRYGREDLDVLGLSFRKDLFIATYQAFPPV PNPPRPPTRLQDRLLRKLGQHAHPFFFTIPQNL PCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEE KSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHF LMSDRSLHLEASLDKELYYHGEPLNVNVHVTNN STKTVKKIKVSVRQYADICLFSTAQYKCPVAQL EQDDQVSPSSTFCKVYTITPLLSDNREKRGLALD GKLKHEDTNLASSTIVKEGANKEVLGILVSYRV KVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPR PQSAAPETDVPVDTNLIEFDTNYATDDDIVFEDF ARLRLKGMKDDDYDDQLC*EAGWEEGRGWGWER *GQD*DPHCQWGIVPAPLPFPSPGSFFNQSLHT LSPIPPRYTLDPLLLNVGINFLTAALLLQPRRGW QAVFIPKFSGRGQ*KEE*QEGKGETKLLLSTSH QHLPLSLSLPPFLQEETLWGQGRFFVSEHKEEN KSFTKH

Frame 1

PACLLGEGGQRRGARDPADASGPGSPRPERGRE GGGRGESAEGARAHWRGEEQGSWQRARRLRASR EPSGRRARAPWGRNPGPGSSRSRALTASSPCTWA SGTS*ITWTKWTL*MAWCLWTLTT*RTAKCL*P SPAPSAMAVKTWMCWACPSAKTCSSPPTRPSPR CPTHPGPPPACRTGC*GSWASMPTPSSSPYPRIF HAPSHCSQAQRIQERPAA*TLRFEPSVLNH*KR KATKGTLCGW*SERCSSPRRNPAPSLQPKPHAT SSCLTGPCTSRLPWTRSCTTMGSPSM*MSTSPTT PPRPSRRSKSL*DSTPTSASSAPPSTSVLWLNS NKMTRYLPAPHSVRCTP*PHCSATTGRSGVSPW MGNSSTRTPTWLPAPS*RRVPTRRCWESWCPTGS R*SWWCLEAGMSLWSCLLFLCTPSPTTTSPSPD PSQPLRRQMSLWTPTSLNLIPTMPQMMTLCLRT LPGFG*RG*RMTTMMINSARKRGGKKGGDGVGRG EGRIKIPTVNGGLSQPLFPSPHLEASSTNPFTL SPPSPQDTHWTLSC*MWALIF*LQLCFSSPAVG GKLCSYLNFLEGDSEKRSDRRERGRQNSYSQPHT NTSHYHSLCPHSFKRRPFGDKAVSLFLSIKKKI NLLLSM

Frame 2

PRVC*ERAGSAAARAIRLTHLAPVPQDQSGAGR EGEEARARRARVRIGAGRSRDLGSGRGGCERAA NRAGGGRAHHGGETRDQGLQEVEP*LQAHRVLG QAGLRRSPGQSGPCRWRGACGP*LPEGPQSVCDP HLRLPLWP*RPGCAGLVLPQRPVHRHLPGLPPG AQPTPAPHPPAGPAAEEAGPACPPLLLHHTPES SMLRHTAARPRGYRKGLRRRL*DSSLLC*ITRRE KPQKELCAAGDPKGAVRPGETRPPAFSRNHTPL PHV*PVPAPRGFPGQGAVLPWGAPQCKCPRHQQ LHQDRQEDQSLCETVRRHLPLQHRPVQVSCGSTR TR*PGISQLHIL*GVHHNPTAQRQPGEAGSRPG WETQARGHQPGFQHHREGGCQQGGAGNPGVLQG QGEAGGVSRRGCLCGAAFCSYAPQAPRPHPPPQT PVSRSGDRCPCGHQPH*I*YQLCHR**HCV*GL CPASAEGDEG*RL**STLLGSGVGRREGMGLGE VRAGLRSPLSMGDCPSPSSLPLTWKLLQPIPSHS LPHPPKIHTGPSLAECGH*FFDCSSASPAPPWV ASCVHT*IFWKGTVKRGVTGGKGGDKTPTLNLT PTPPIITLSAPIPSRGDPLGTRPFLCF*A*RRK* IFY*A*