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Sequences

Sequence NM_001617

ATTTCCTCCCAGCCTCGTGCGGGAAATGGCTTTAATTCTGACGGCAGGGCTGTGAGGGACTAGCGGGAACCCGAGCCTTTTGTCAAGGAACTGCGGCGTC GGTGGCCAGTCATCCCCGCCGCCGCGGAGCCGCTGCACTGCTGGGGGATCTCCCAGCAGCTCTGACGAGCGCGGGCTGCAGCATGGGCAGAAAACGCTGC CCTGCAGATTAGCTGGGTGGATTTTTTAAGCGCACCCCACCCCCCAAACCCATAAAATAACAAAACCAACCCGCAGTGGCCGACCGGAGATAGCTAAGAT GCCGCGCAGGAGTTTCCACCTGGATGTTTGAGGTTGTGTAGATGTGGCCGGCACCCTTGAGAGTGGAGCTAGGGGGTGCAGACTGAGCAGTGAACAGAAG GAGCCTTGGACAGGGCTGGGCCAGCCTCCCGAGTTCCAGGAGCGAATTGCAAACCCACCGGGAAAATGAGCGAAGAGACGGTCCCCGAGGCTGCCTCGCC GCCGCCCCCGCAGGGGCAGCCTTACTTTGACCGCTTCTCAGAGGACGACCCCGAGTACATGCGCCTTCGCAACCGGGCGGCGGACCTGCGGCAGGACTTC AACCTGATGGAGCAGAAGAAGCGCGTCACCATGATCCTGCAGAGTCCCTCTTTCAGGGAGGAGCTGGAAGGCCTCATCCAGGAGCAGATGAAGAAGGGGA ACAACTCCTCCAACATCTGGGCCCTGCGACAGATCGCGGACTTCATGGCCAGCACCTCCCACGCAGTCTTCCCGACATCTTCCATGAATGTCTCCATGAT GACGCCTATCAATGACCTCCACACAGCTGACTCCCTGAACCTGGCCAAAGGGGAGCGGCTCATGCGGTGCAAGATCAGCAGTGTCTACCGACTCCTGGAC CTCTATGGCTGGGCCCAGCTGAGTGACACCTATGTCACGTTGAGAGTCAGCAAGGAGCAGGACCACTTCCTGATCAGCCCTAAGGGAGTTTCTTGCAGTG AAGTCACAGCGTCCAGCCTGATCAAGGTGAACATTCTGGGAGAGGTGGTGGAGAAGGGCAGCAGCTGCTTCCCAGTGGACACCACAGGCTTCTGTCTGCA CTCGGCCATCTATGCAGCGAGGCCCGACGTGCGCTGCATCATCCACCTGCACACACCGGCCACAGCAGCGGTGTCGGCCATGAAGTGGGGCCTCCTGCCT GTCTCCCACAATGCCCTGCTGGTGGGGGACATGGCCTATTATGACTTCAATGGGGAAATGGAGCAGGAAGCCGATCGGATCAACCTGCAGAAGTGCCTTG GACCCACCTGCAAGATCCTGGTGCTAAGAAACCATGGAGTGGTTGCTCTGGGTGACACGGTAGAGGAGGCATTTTACAAGATCTTCCACCTGCAGGCTGC ATGTGAGATACAGGTGTCGGCTCTGTCCAGTGCCGGGGGAGTGGAGAACCTCATCCTCCTGGAGCAGGAGAAGCACCGGCCCCATGAGGTGGGCTCCGTG CAGTGGGCCGGGAGCACCTTTGGGCCTATGCAGAAGAGTCGGCTGGGGGAGCATGAGTTTGAGGCCCTCATGAGGATGCTGGACAACCTGGGCTACAGAA CAGGTTACACGTATCGCCACCCCTTTGTTCAAGAGAAAACCAAACACAAAAGTGAGGTGGAGATTCCAGCCACGGTCACAGCCTTCGTGTTTGAGGAGGA CGGTGCCCCGGTGCCCGCCCTGCGACAGCATGCCCAGAAGCAGCAGAAGGAGAAGACCCGCTGGCTCAATACGCCCAACACCTACCTGCGGGTCAATGTG GCCGATGAGGTCCAGAGGAGCATGGGCAGCCCCCGACCCAAGACCACGTGGATGAAGGCTGACGAGGTGGAGAAATCCAGCAGTGGCATGCCGATTCGCA TCGAAAACCCAAACCAATTTGTGCCTCTCTATACTGACCCCCAGGAAGTACTGGAGATGAGGAACAAGATTCGAGAACAAAACCGACAAGATGTGAAGTC AGCGGGGCCTCAGTCCCAGCTCCTGGCGAGCGTCATTGCCGAGAAGAGCCGAAGCCCGTCTACAGAGAGCCAGCTGATGTCCAAGGGAGACGAGGATACC AAAGACGATTCAGAGGAGACGGTGCCCAACCCCTTCAGCCAACTCACTGACCAGGAGTTGGAGGAGTACAAGAAAGAGGTGGAGAGGAAGAAACTAGAAC TTGATGGAGAGAAAGAAACTGCCCCAGAAGAGCCTGGCTCACCTGCAAAGTCTGCACCTGCTTCTCCAGTGCAGAGCCCAGCGAAGGAGGCAGAGACAAA GAGCCCTTTAGTCTCTCCTTCCAAGTCTTTAGAGGAAGGTACTAAGAAGACAGAAACAAGCAAAGCCGCCACCACAGAGCCCGAAACAACCCAGCCGGAA GGGGTGGTGGTCAACGGGAGGGAGGAGGAGCAGACGGCAGAGGAAATCCTCAGCAAAGGCCTGAGCCAGATGACCACCAGTGCTGACACGGATGTTGATA CCTCTAAGGACAAAACCGAGTCGGTCACCAGCGGCCCCATGTCCCCAGAGGGCTCACCTTCCAAGTCTCCCTCAAAGAAGAAAAAGAAATTCCGAACCCC CTCCTTCCTGAAAAAGAGCAAAAAGAAGGAGAAAGTGGAGTCCTGATTCATGACACCCTTGGGCTCCCTCCTGCCTCCTCTCTCTCCTCCCCTTCCCTTC TCCCATCTCTGTCCCTGCAAGCACAGGGCTAAGGAGGGATAGAGTAGGACCCTGGACCACATTCGGAAGGGGAACTTAGAGATCACCCGACCAACCCTTC GTTTTACAGTTGCCCAAGAGAAATCAGGTGACTTGCCCAAGGTCACACAGCTAGTTAGCGGCAGAGCCTGCACTCGAATTCAGGTCTCCTGACTTCCAGT CCAGTGCTCCTTCTACTACACAACACTGCCTAGTTGTGGGCTGCCTTTGTTTGGATGCTGTCCACCAATCTGAGCCTAGGGCAAGAAGGCCAGAAATGGG CCGTGAGCTCTCACAGGCTCAGACTAAATCAGAGGTCAAGGCTTCCCCTGAGTAAGGTCCATTTCTTCCCAGGAATCCAATCTCCTGTGGATGGAGCTAT CTCTACATTTAAAAATCTCTTCTCTTTTCCACTTTGGGTCCCTGCCCTGCTGCTCAAAGTGACTAGCCAAATTGACCCCTCCAACAGAAAGTAATCTTTG TTCCCAAGGGCTGATGGCTTAGCTTGTACTACCCCAAACATTAACCCTGAGCTTTCTTCATGGAACCTCTTGAATGATGGATGGAAGAGCTATAAGAGGT GGTAGGCATAGGGGCAAGCCATGTAAGCTGAGGATTGGGGATGGTTTCATCAACATAAGAGGCCAGGAACTTGACCCCTTTGAATTGTGCATCTCAGGCA CTTCAAAACTAAAACCAAATTTAGCATAGGAAAAAGTTGTTTAATGCTCAGGGCAGAAATTTGGGGAAGTTGAAATCCTCTGTTGGCTTTGGGTTGTATA AGGAGGATCAAAACAACAGAGGAAATGCTGACTTTCTAGCTTTGCATGACACCTGGAGCAATGCACTGTACCTGCCTCACTCCTGTCCAGTGGTCAGGTT TCCCCTGACCTTCCCTCACCCCCAGAAACACTTGCTTACAGACCGAAACTGGCATCTTACTCTTGGCACCTTGACTTGCACCCTCTGAGGTTCCAACTCA GTCATTCTTTGTCCAGCAGAGGAGAATCAGAAATGAGCCCTTCAGGATTAATCCTCTTGCACCAGCTCTCAGAGAAATGCTGGGTATCCCTGTCCTTGTC CCTATCTGTCCATCCTGGGGCCTGGTAATGGCCACAGTTATTGTTTTAAATGCCAACACTGTCTTCTCATGTTCTTCCGTGGGGCATTGATTAATGAGCA TTTGTTGGCTCCTAAAAATTAGACAATCCATTCTCTTGAAA

refseq_ADD2.F1 (forward primer)
refseq_ADD2.R1 (reverse primer)
Single exon skipping

Frame 0

ISSQPRAGNGFNSDGRAVRD*REPEPFVKELRR RWPVIPAAAEPLHCWGISQQL*RARAAAWAENAA LQISWVDFLSAPHPPNP*NNKTNPQWPTGDS*D AAQEFPPGCLRLCRCGRHP*EWS*GVQTEQ*TE GALDRAGPASRVPGANCKPTGKMSEETVPEAASP PPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDF NLMEQKKRVTMILQSPSFREELEGLIQEQMKKG NNSSNIWALRQIADFMASTSHAVFPTSSMNVSMM TPINDLHTADSLNLAKGERLMRCKISSVYRLLD LYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCS EVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLH SAIYAARPDVRCIIHLHTPATAAVSAMKWGLLP VSHNALLVGDMAYYDFNGEMEQEADRINLQKCL GPTCKILVLRNHGVVALGDTVEEAFYKIFHLQAA CEIQVSALSSAGGVENLILLEQEKHRPHEVGSV QWAGSTFGPMQKSRLGEHEFEALMRMLDNLGYR TGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEED GAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNV ADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIR IENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKS AGPQSQLLASVIAEKSRSPSTESQLMSKGDEDT KDDSEETVPNPFSQLTDQELEEYKKEVERKKLE LDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK SPLVSPSKSLEEGTKKTETSKAATTEPETTQPE GVVVNGREEEQTAEEILSKGLSQMTTSADTDVD TSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTP SFLKKSKKKEKVES*FMTPLGSLLPPLSPPLPF SHLCPCKHRAKEG*SRTLDHIRKGNLEITRPTL RFTVAQEKSGDLPKVTQLVSGRACTRIQVS*LPV QCSFYYTTLPSCGLPLFGCCPPI*A*GKKARNG P*ALTGSD*IRGQGFP*VRSISSQESNLLWMEL SLHLKISSLFHFGSLPCCSK*LAKLTPPTESNLC SQGLMA*LVLPQTLTLSFLHGTS*MMDGRAIRG GRHRGKPCKLRIGDGFINIRGQELDPFELCISG TSKLKPNLA*EKVV*CSGQKFGEVEILCWLWVV* GGSKQQRKC*LSSFA*HLEQCTVPASLLSSGQV SPDLPSPPETLAYRPKLASYSWHLDLHPLRFQL SHSLSSRGESEMSPSGLILLHQLSEKCWVSLSLS LSVHPGAW*WPQLLF*MPTLSSHVLPWGID**A FVGS*KLDNPFS*

Frame 1

FPPSLVREMALILTAGL*GTSGNPSLLSRNCGV GGQSSPPPRSRCTAGGSPSSSDERGLQHGQKTL PCRLAGWIF*AHPTPQTHKITKPTRSGRPEIAKM PRRSFHLDV*GCVDVAGTLESGARGCRLSSEQK EPWTGLGQPPEFQERIANPPGK*AKRRSPRLPR RRPRRGSLTLTASQRTTPSTCAFATGRRTCGRTS T*WSRRSASP*SCRVPLSGRSWKASSRSR*RRG TTPPTSGPCDRSRTSWPAPPTQSSRHLP*MSP* *RLSMTSTQLTP*TWPKGSGSCGARSAVSTDSWT SMAGPS*VTPMSR*ESARSRTTS*SALREFLAV KSQRPA*SR*TFWERWWRRAAAASQWTPQASVC TRPSMQRGPTCAASSTCTHRPQQRCRP*SGASCL SPTMPCWWGTWPIMTSMGKWSRKPIGSTCRSAL DPPARSWC*ETMEWLLWVTR*RRHFTRSSTCRL HVRYRCRLCPVPGEWRTSSSWSRRSTGPMRWAPC SGPGAPLGLCRRVGWGSMSLRPS*GCWTTWATE QVTRIATPLFKRKPNTKVRWRFQPRSQPSCLRR TVPRCPPCDSMPRSSRRRRPAGSIRPTPTCGSMW PMRSRGAWAAPDPRPRG*RLTRWRNPAVACRFA SKTQTNLCLSILTPRKYWR*GTRFENKTDKM*S QRGLSPSSWRASLPRRAEARLQRAS*CPRETRIP KTIQRRRCPTPSANSLTRSWRSTRKRWRGRN*N LMERKKLPQKSLAHLQSLHLLLQCRAQRRRQRQ RAL*SLLPSL*RKVLRRQKQAKPPPQSPKQPSRK GWWSTGGRRSRRQRKSSAKA*AR*PPVLTRMLI PLRTKPSRSPAAPCPQRAHLPSLPQRRKRNSEP PPS*KRAKRRRKWSPDS*HPWAPSCLLSLLPFPS PISVPASTGLRRDRVGPWTTFGRGT*RSPDQPF VLQLPKRNQVTCPRSHS*LAAEPALEFRSPDFQ SSAPSTTQHCLVVGCLCLDAVHQSEPRARRPEMG RELSQAQTKSEVKASPE*GPFLPRNPISCGWSY LYI*KSLLFSTLGPCPAAQSD*PN*PLQQKVIF VPKG*WLSLYYPKH*P*AFFMEPLE*WMEEL*EV VGIGASHVS*GLGMVSST*EARNLTPLNCASQA LQN*NQI*HRKKLFNAQGRNLGKLKSSVGFGLY KEDQNNRGNADFLALHDTWSNALYLPHSCPVVRF PLTFPHPQKHLLTDRNWHLTLGTLTCTL*GSNS VILCPAEENQK*ALQD*SSCTSSQRNAGYPCPC PYLSILGPGNGHSYCFKCQHCLLMFFRGALINEH LLAPKN*TIHSLE

Frame 2

FLPASCGKWL*F*RQGCEGLAGTRAFCQGTAAS VASHPRRRGAAALLGDLPAALTSAGCSMGRKRC PAD*LGGFFKRTPPPKPIK*QNQPAVADRR*LR CRAGVSTWMFEVV*MWPAPLRVELGGAD*AVNRR SLGQGWASLPSSRSELQTHRENERRDGPRGCLA AAPAGAALL*PLLRGRPRVHAPSQPGGGPAAGL QPDGAEEARHHDPAESLFQGGAGRPHPGADEEGE QLLQHLGPATDRGLHGQHLPRSLPDIFHECLHD DAYQ*PPHS*LPEPGQRGAAHAVQDQQCLPTPG PLWLGPAE*HLCHVESQQGAGPLPDQP*GSFLQ* SHSVQPDQGEHSGRGGGEGQQLLPSGHHRLLSA LGHLCSEARRALHHPPAHTGHSSGVGHEVGPPA CLPQCPAGGGHGLL*LQWGNGAGSRSDQPAEVPW THLQDPGAKKPWSGCSG*HGRGGILQDLPPAGC M*DTGVGSVQCRGSGEPHPPGAGEAPAP*GGLR AVGREHLWAYAEESAGGA*V*GPHEDAGQPGLQN RLHVSPPLCSRENQTQK*GGDSSHGHSLRV*GG RCPGARPATACPEAAEGEDPLAQYAQHLPAGQC GR*GPEEHGQPPTQDHVDEG*RGGEIQQWHADSH RKPKPICASLY*PPGSTGDEEQDSRTKPTRCEV SGASVPAPGERHCREEPKPVYREPADVQGRRGY QRRFRGDGAQPLQPTH*PGVGGVQERGGEEETRT *WRERNCPRRAWLTCKVCTCFSSAEPSEGGRDK EPFSLSFQVFRGRY*EDRNKQSRHHRARNNPAG RGGGQREGGGADGRGNPQQRPEPDDHQC*HGC*Y L*GQNRVGHQRPHVPRGLTFQVSLKEEKEIPNP LLPEKEQKEGESGVLIHDTLGLPPASSLSSPSL LPSLSLQAQG*GGIE*DPGPHSEGELRDHPTNPS FYSCPREIR*LAQGHTAS*RQSLHSNSGLLTSS PVLLLLHNTA*LWAAFVWMLSTNLSLGQEGQKW AVSSHRLRLNQRSRLPLSKVHFFPGIQSPVDGAI STFKNLFSFPLWVPALLLKVTSQIDPSNRK*SL FPRADGLACTTPNINPELSSWNLLNDGWKSYKR W*A*GQAM*AEDWGWFHQHKRPGT*PL*IVHLRH FKTKTKFSIGKSCLMLRAEIWGS*NPLLALGCI RRIKTTEEMLTF*LCMTPGAMHCTCLTPVQWSG FP*PSLTPRNTCLQTETGILLLAP*LAPSEVPTQ SFFVQQRRIRNEPFRINPLAPALREMLGIPVLV PICPSWGLVMATVIVLNANTVFSCSSVGH*LMS ICWLLKIRQSILLK

Sequence NM_017483

ATTTCCTCCCAGCCTCGTGCGGGAAATGGCTTTAATTCTGACGGCAGGGCTGTGAGGGACTAGCGGGAACCCGAGCCTTTTGTCAAGGAACTGCGGCGTC GGTGGCCAGTCATCCCCGCCGCCGCGGAGCCGCTGCACTGCTGGGGGATCTCCCAGCAGCTCTGACGAGCGCGGGCTGCAGCATGGGCAGAAAACGCTGC CCTGCAGATTAGCTGGGTGGATTTTTTAAGCGCACCCCACCCCCCAAACCCATAAAATAACAAAACCAACCCGCAGTGGCCGACCGGAGATAGCTAAGAT GCCGCGCAGGAGTTTCCACCTGGATGTTTGAGGTTGTGTAGATGTGGCCGGCACCCTTGAGAGTGGAGCTAGGGGGTGCAGACTGAGCAGTGAACAGAAG GAGCCTTGGACAGGGCTGGGCCAGCCTCCCGAGTTCCAGGAGCGAATTGCAAACCCACCGGGAAAATGAGCGAAGAGACGGTCCCCGAGGCTGCCTCGCC GCCGCCCCCGCAGGGGCAGCCTTACTTTGACCGCTTCTCAGAGGACGACCCCGAGTACATGCGCCTTCGCAACCGGGCGGCGGACCTGCGGCAGGACTTC AACCTGATGGAGCAGAAGAAGCGCGTCACCATGATCCTGCAGAGTCCCTCTTTCAGGGAGGAGCTGGAAGGCCTCATCCAGGAGCAGATGAAGAAGGGGA ACAACTCCTCCAACATCTGGGCCCTGCGACAGATCGCGGACTTCATGGCCAGCACCTCCCACGCAGTCTTCCCGACATCTTCCATGAATGTCTCCATGAT GACGCCTATCAATGACCTCCACACAGCTGACTCCCTGAACCTGGCCAAAGGGGAGCGGCTCATGCGGTGCAAGATCAGCAGTGTCTACCGACTCCTGGAC CTCTATGGCTGGGCCCAGCTGAGTGACACCTATGTCACGTTGAGAGTCAGCAAGGAGCAGGACCACTTCCTGATCAGCCCTAAGGGAGTTTCTTGCAGTG AAGTCACAGCGTCCAGCCTGATCAAGGAAGTACTGGAGATGAGGAACAAGATTCGAGAACAAAACCGACAAGATGTGAAGTCAGCGGGGCCTCAGTCCCA GCTCCTGGCGAGCGTCATTGCCGAGAAGAGCCGAAGCCCGTCTACAGAGAGCCAGCTGATGTCCAAGGGAGACGAGGATACCAAAGACGATTCAGAGGAG ACGGTGCCCAACCCCTTCAGCCAACTCACTGACCAGGAGTTGGAGGAGTACAAGAAAGAGGTGGAGAGGAAGAAACTAGAACTTGATGGAGAGAAAGAAA CTGCCCCAGAAGAGCCTGGCTCACCTGCAAAGTCTGCACCTGCTTCTCCAGTGCAGAGCCCAGCGAAGGAGGCAGAGACAAAGAGCCCTTTAGTCTCTCC TTCCAAGTCTTTAGAGGAAGGTACTAAGAAGACAGAAACAAGCAAAGCCGCCACCACAGAGCCCGAAACAACCCAGCCGGAAGGGGTGGTGGTCAACGGG AGGGAGGAGGAGCAGACGGCAGAGGAAATCCTCAGCAAAGGCCTGAGCCAGATGACCACCAGTGCTGACACGGATGTTGATACCTCTAAGGACAAAACCG AGTCGGTCACCAGCGGCCCCATGTCCCCAGAGGGCTCACCTTCCAAGTCTCCCTCAAAGAAGAAAAAGAAATTCCGAACCCCCTCCTTCCTGAAAAAGAG CAAAAAGAAGGAGAAAGTGGAGTCCTGATTCATGACACCCTTGGGCTCCCTCCTGCCTCCTCTCTCTCCTCCCCTTCCCTTCTCCCATCTCTGTCCCTGC AAGCACAGGGCTAAGGAGGGATAGAGTAGGACCCTGGACCACATTCGGAAGGGGAACTTAGAGATCACCCGACCAACCCTTCGTTTTACAGTTGCCCAAG AGAAATCAGGTGACTTGCCCAAGGTCACACAGCTAGTTAGCGGCAGAGCCTGCACTCGAATTCAGGTCTCCTGACTTCCAGTCCAGTGCTCCTTCTACTA CACAACACTGCCTAGTTGTGGGCTGCCTTTGTTTGGATGCTGTCCACCAATCTGAGCCTAGGGCAAGAAGGCCAGAAATGGGCCGTGAGCTCTCACAGGC TCAGACTAAATCAGAGGTCAAGGCTTCCCCTGAGTAAGGTCCATTTCTTCCCAGGAATCCAATCTCCTGTGGATGGAGCTATCTCTACATTTAAAAATCT CTTCTCTTTTCCACTTTGGGTCCCTGCCCTGCTGCTCAAAGTGACTAGCCAAATTGACCCCTCCAACAGAAAGTAATCTTTGTTCCCAAGGGCTGATGGC TTAGCTTGTACTACCCCAAACATTAACCCTGAGCTTTCTTCATGGAACCTCTTGAATGATGGATGGAAGAGCTATAAGAGGTGGTAGGCATAGGGGCAAG CCATGTAAGCTGAGGATTGGGGATGGTTTCATCAACATAAGAGGCCAGGAACTTGACCCCTTTGAATTGTGCATCTCAGGCACTTCAAAACTAAAACCAA ATTTAGCATAGGAAAAAGTTGTTTAATGCTCAGGGCAGAAATTTGGGGAAGTTGAAATCCTCTGTTGGCTTTGGGTTGTATAAGGAGGATCAAAACAACA GAGGAAATGCTGACTTTCTAGCTTTGCATGACACCTGGAGCAATGCACTGTACCTGCCTCACTCCTGTCCAGTGGTCAGGTTTCCCCTGACCTTCCCTCA CCCCCAGAAACACTTGCTTACAGACCGAAACTGGCATCTTACTCTTGGCACCTTGACTTGCACCCTCTGAGGTTCCAACTCAGTCATTCTTTGTCCAGCA GAGGAGAATCAGAAATGAGCCCTTCAGGATTAATCCTCTTGCACCAGCTCTCAGAGAAATGCTGGGTATCCCTGTCCTTGTCCCTATCTGTCCATCCTGG GGCCTGGTAATGGCCACAGTTATTGTTTTAAATGCCAACACTGTCTTCTCATGTTCTTCCGTGGGGCATTGATTAATGAGCATTTGTTGGCTCCTAAAAA TTAGACAATCCATTCTCTTGAAA

refseq_ADD2.F1 (forward primer)
refseq_ADD2.R1 (reverse primer)
Single exon skipping

Frame 0

ISSQPRAGNGFNSDGRAVRD*REPEPFVKELRR RWPVIPAAAEPLHCWGISQQL*RARAAAWAENAA LQISWVDFLSAPHPPNP*NNKTNPQWPTGDS*D AAQEFPPGCLRLCRCGRHP*EWS*GVQTEQ*TE GALDRAGPASRVPGANCKPTGKMSEETVPEAASP PPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDF NLMEQKKRVTMILQSPSFREELEGLIQEQMKKG NNSSNIWALRQIADFMASTSHAVFPTSSMNVSMM TPINDLHTADSLNLAKGERLMRCKISSVYRLLD LYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCS EVTASSLIKEVLEMRNKIREQNRQDVKSAGPQSQ LLASVIAEKSRSPSTESQLMSKGDEDTKDDSEE TVPNPFSQLTDQELEEYKKEVERKKLELDGEKE TAPEEPGSPAKSAPASPVQSPAKEAETKSPLVSP SKSLEEGTKKTETSKAATTEPETTQPEGVVVNG REEEQTAEEILSKGLSQMTTSADTDVDTSKDKT ESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKS KKKEKVES*FMTPLGSLLPPLSPPLPFSHLCPC KHRAKEG*SRTLDHIRKGNLEITRPTLRFTVAQ EKSGDLPKVTQLVSGRACTRIQVS*LPVQCSFYY TTLPSCGLPLFGCCPPI*A*GKKARNGP*ALTG SD*IRGQGFP*VRSISSQESNLLWMELSLHLKI SSLFHFGSLPCCSK*LAKLTPPTESNLCSQGLMA *LVLPQTLTLSFLHGTS*MMDGRAIRGGRHRGK PCKLRIGDGFINIRGQELDPFELCISGTSKLKP NLA*EKVV*CSGQKFGEVEILCWLWVV*GGSKQQ RKC*LSSFA*HLEQCTVPASLLSSGQVSPDLPS PPETLAYRPKLASYSWHLDLHPLRFQLSHSLSS RGESEMSPSGLILLHQLSEKCWVSLSLSLSVHPG AW*WPQLLF*MPTLSSHVLPWGID**AFVGS*K LDNPFS*

Frame 1

FPPSLVREMALILTAGL*GTSGNPSLLSRNCGV GGQSSPPPRSRCTAGGSPSSSDERGLQHGQKTL PCRLAGWIF*AHPTPQTHKITKPTRSGRPEIAKM PRRSFHLDV*GCVDVAGTLESGARGCRLSSEQK EPWTGLGQPPEFQERIANPPGK*AKRRSPRLPR RRPRRGSLTLTASQRTTPSTCAFATGRRTCGRTS T*WSRRSASP*SCRVPLSGRSWKASSRSR*RRG TTPPTSGPCDRSRTSWPAPPTQSSRHLP*MSP* *RLSMTSTQLTP*TWPKGSGSCGARSAVSTDSWT SMAGPS*VTPMSR*ESARSRTTS*SALREFLAV KSQRPA*SRKYWR*GTRFENKTDKM*SQRGLSP SSWRASLPRRAEARLQRAS*CPRETRIPKTIQRR RCPTPSANSLTRSWRSTRKRWRGRN*NLMERKK LPQKSLAHLQSLHLLLQCRAQRRRQRQRAL*SL LPSL*RKVLRRQKQAKPPPQSPKQPSRKGWWSTG GRRSRRQRKSSAKA*AR*PPVLTRMLIPLRTKP SRSPAAPCPQRAHLPSLPQRRKRNSEPPPS*KR AKRRRKWSPDS*HPWAPSCLLSLLPFPSPISVPA STGLRRDRVGPWTTFGRGT*RSPDQPFVLQLPK RNQVTCPRSHS*LAAEPALEFRSPDFQSSAPST TQHCLVVGCLCLDAVHQSEPRARRPEMGRELSQA QTKSEVKASPE*GPFLPRNPISCGWSYLYI*KS LLFSTLGPCPAAQSD*PN*PLQQKVIFVPKG*W LSLYYPKH*P*AFFMEPLE*WMEEL*EVVGIGAS HVS*GLGMVSST*EARNLTPLNCASQALQN*NQ I*HRKKLFNAQGRNLGKLKSSVGFGLYKEDQNN RGNADFLALHDTWSNALYLPHSCPVVRFPLTFPH PQKHLLTDRNWHLTLGTLTCTL*GSNSVILCPA EENQK*ALQD*SSCTSSQRNAGYPCPCPYLSIL GPGNGHSYCFKCQHCLLMFFRGALINEHLLAPKN *TIHSLE

Frame 2

FLPASCGKWL*F*RQGCEGLAGTRAFCQGTAAS VASHPRRRGAAALLGDLPAALTSAGCSMGRKRC PAD*LGGFFKRTPPPKPIK*QNQPAVADRR*LR CRAGVSTWMFEVV*MWPAPLRVELGGAD*AVNRR SLGQGWASLPSSRSELQTHRENERRDGPRGCLA AAPAGAALL*PLLRGRPRVHAPSQPGGGPAAGL QPDGAEEARHHDPAESLFQGGAGRPHPGADEEGE QLLQHLGPATDRGLHGQHLPRSLPDIFHECLHD DAYQ*PPHS*LPEPGQRGAAHAVQDQQCLPTPG PLWLGPAE*HLCHVESQQGAGPLPDQP*GSFLQ* SHSVQPDQGSTGDEEQDSRTKPTRCEVSGASVP APGERHCREEPKPVYREPADVQGRRGYQRRFRG DGAQPLQPTH*PGVGGVQERGGEEETRT*WRERN CPRRAWLTCKVCTCFSSAEPSEGGRDKEPFSLS FQVFRGRY*EDRNKQSRHHRARNNPAGRGGGQR EGGGADGRGNPQQRPEPDDHQC*HGC*YL*GQNR VGHQRPHVPRGLTFQVSLKEEKEIPNPLLPEKE QKEGESGVLIHDTLGLPPASSLSSPSLLPSLSL QAQG*GGIE*DPGPHSEGELRDHPTNPSFYSCPR EIR*LAQGHTAS*RQSLHSNSGLLTSSPVLLLL HNTA*LWAAFVWMLSTNLSLGQEGQKWAVSSHR LRLNQRSRLPLSKVHFFPGIQSPVDGAISTFKNL FSFPLWVPALLLKVTSQIDPSNRK*SLFPRADG LACTTPNINPELSSWNLLNDGWKSYKRW*A*GQ AM*AEDWGWFHQHKRPGT*PL*IVHLRHFKTKTK FSIGKSCLMLRAEIWGS*NPLLALGCIRRIKTT EEMLTF*LCMTPGAMHCTCLTPVQWSGFP*PSL TPRNTCLQTETGILLLAP*LAPSEVPTQSFFVQQ RRIRNEPFRINPLAPALREMLGIPVLVPICPSW GLVMATVIVLNANTVFSCSSVGH*LMSICWLLK IRQSILLK

Sequence NM_017488

ATTTCCTCCCAGCCTCGTGCGGGAAATGGCTTTAATTCTGACGGCAGGGCTGTGAGGGACTAGCGGGAACCCGAGCCTTTTGTCAAGGAACTGCGGCGTC GGTGGCCAGTCATCCCCGCCGCCGCGGAGCCGCTGCACTGCTGGGGGATCTCCCAGCAGCTCTGACGAGCGCGGGCTGCAGCATGGGCAGAAAACGCTGC CCTGCAGATTAGCTGGGTGGATTTTTTAAGCGCACCCCACCCCCCAAACCCATAAAATAACAAAACCAACCCGCAGTGGCCGACCGGAGATAGCTAAGAT GCCGCGCAGGAGTTTCCACCTGGATGTTTGAGGTTGTGTAGATGTGGCCGGCACCCTTGAGAGTGGAGCTAGGGGGTGCAGACTGAGCAGTGAACAGAAG GAGCCTTGGACAGGGCTGGGCCAGCCTCCCGAGTTCCAGGAGCGAATTGCAAACCCACCGGGAAAATGAGCGAAGAGACGGTCCCCGAGGCTGCCTCGCC GCCGCCCCCGCAGGGGCAGCCTTACTTTGACCGCTTCTCAGAGGACGACCCCGAGTACATGCGCCTTCGCAACCGGGCGGCGGACCTGCGGCAGGACTTC AACCTGATGGAGCAGAAGAAGCGCGTCACCATGATCCTGCAGAGTCCCTCTTTCAGGGAGGAGCTGGAAGGCCTCATCCAGGAGCAGATGAAGAAGGGGA ACAACTCCTCCAACATCTGGGCCCTGCGACAGATCGCGGACTTCATGGCCAGCACCTCCCACGCAGTCTTCCCGACATCTTCCATGAATGTCTCCATGAT GACGCCTATCAATGACCTCCACACAGCTGACTCCCTGAACCTGGCCAAAGGGGAGCGGCTCATGCGGTGCAAGATCAGCAGTGTCTACCGACTCCTGGAC CTCTATGGCTGGGCCCAGCTGAGTGACACCTATGTCACGTTGAGAGTCAGCAAGGAGCAGGACCACTTCCTGATCAGCCCTAAGGGAGTTTCTTGCAGTG AAGTCACAGCGTCCAGCCTGATCAAGGTGAACATTCTGGGAGAGGTGGTGGAGAAGGGCAGCAGCTGCTTCCCAGTGGACACCACAGGCTTCTGTCTGCA CTCGGCCATCTATGCAGCGAGGCCCGACGTGCGCTGCATCATCCACCTGCACACACCGGCCACAGCAGCGGTGTCGGCCATGAAGTGGGGCCTCCTGCCT GTCTCCCACAATGCCCTGCTGGTGGGGGACATGGCCTATTATGACTTCAATGGGGAAATGGAGCAGGAAGCCGATCGGATCAACCTGCAGAAGTGCCTTG GACCCACCTGCAAGATCCTGGTGCTAAGAAACCATGGAGTGGTTGCTCTGGGTGACACGGTAGAGGAGGCATTTTACAAGATCTTCCACCTGCAGGCTGC ATGTGAGATACAGGTGTCGGCTCTGTCCAGTGCCGGGGGAGTGGAGAACCTCATCCTCCTGGAGCAGGAGAAGCACCGGCCCCATGAGGTGGGCTCCGTG CAGTGGGCCGGGAGCACCTTTGGGCCTATGCAGAAGAGTCGGCTGGGGGAGCATGAGTTTGAGGCCCTCATGAGGATGCTGGACAACCTGGGCTACAGAA CAGGTTACACGTATCGCCACCCCTTTGTTCAAGAGAAAACCAAACACAAAAGTGAGGTGGAGATTCCAGCCACGGTCACAGCCTTCGTGTTTGAGGAGGA CGGTGCCCCGGTGCCCGCCCTGCGACAGCATGCCCAGAAGCAGCAGAAGGAGAAGACCCGCTGGCTCAATACGCCCAACACCTACCTGCGGGTCAATGTG GCCGATGAGGTCCAGAGGAGCATGGGCAGCCCCCGACCCAAGACCACGTGGATGAAGGCTGACGAGGTGGAGAAATCCAGCAGTGGCATGCCGATTCGCA TCGAAAACCCAAACCAATTTGTGCCTCTCTATACTGACCCCCAGGAAGTACTGGAGATGAGGAACAAGATTCGAGAACAAAACCGACAAGATGTGAAGTC AGCGGGGCCTCAGTCCCAGCTCCTGGCGAGCGTCATTGCCGAGAAGAGCCGAAGCCCGTCTACAGAGAGCCAGCTGATGTCCAAGGGAGACGAGGATACC AAAGACGATTCAGAGGAGACGGTGCCCAACCCCTTCAGCCAACTCACTGACCAGGAGTTGGAGGAGTACAAGAAAGAGGTGGAGAGGAAGAAACTAGAAC TTGATGAGACAGGACAGGAACGAGAGCCAGGCTCTGGTCCGGCCGTGTGCGAGTTCTTCAGCGTTGCCCTCCACATCTGGAGTAACATATTGGAGAGAAA GAAACTGCCCCAGAAGAGCCTGGCTCACCTGCAAAGTCTGCACCTGCTTCTCCAGTGCAGAGCCCAGCGAAGGAGGCAGAGACAAAGAGCCCTTTAGTCT CTCCTTCCAAGTCTTTAGAGGAAGGTACTAAGAAGACAGAAACAAGCAAAGCCGCCACCACAGAGCCCGAAACAACCCAGCCGGAAGGGGTGGTGGTCAA CGGGAGGGAGGAGGAGCAGACGGCAGAGGAAATCCTCAGCAAAGGCCTGAGCCAGATGACCACCAGTGCTGACACGGATGTTGATACCTCTAAGGACAAA ACCGAGTCGGTCACCAGCGGCCCCATGTCCCCAGAGGGCTCACCTTCCAAGTCTCCCTCAAAGAAGAAAAAGAAATTCCGAACCCCCTCCTTCCTGAAAA AGAGCAAAAAGAAGGAGAAAGTGGAGTCCTGATTCATGACACCCTTGGGCTCCCTCCTGCCTCCTCTCTCTCCTCCCCTTCCCTTCTCCCATCTCTGTCC CTGCAAGCACAGGGCTAAGGAGGGATAGAGTAGGACCCTGGACCACATTCGGAAGGGGAACTTAGAGATCACCCGACCAACCCTTCGTTTTACAGTTGCC CAAGAGAAATCAGGTGACTTGCCCAAGGTCACACAGCTAGTTAGCGGCAGAGCCTGCACTCGAATTCAGGTCTCCTGACTTCCAGTCCAGTGCTCCTTCT ACTACACAACACTGCCTAGTTGTGGGCTGCCTTTGTTTGGATGCTGTCCACCAATCTGAGCCTAGGGCAAGAAGGCCAGAAATGGGCCGTGAGCTCTCAC AGGCTCAGACTAAATCAGAGGTCAAGGCTTCCCCTGAGTAAGGTCCATTTCTTCCCAGGAATCCAATCTCCTGTGGATGGAGCTATCTCTACATTTAAAA ATCTCTTCTCTTTTCCACTTTGGGTCCCTGCCCTGCTGCTCAAAGTGACTAGCCAAATTGACCCCTCCAACAGAAAGTAATCTTTGTTCCCAAGGGCTGA TGGCTTAGCTTGTACTACCCCAAACATTAACCCTGAGCTTTCTTCATGGAACCTCTTGAATGATGGATGGAAGAGCTATAAGAGGTGGTAGGCATAGGGG CAAGCCATGTAAGCTGAGGATTGGGGATGGTTTCATCAACATAAGAGGCCAGGAACTTGACCCCTTTGAATTGTGCATCTCAGGCACTTCAAAACTAAAA CCAAATTTAGCATAGGAAAAAGTTGTTTAATGCTCAGGGCAGAAATTTGGGGAAGTTGAAATCCTCTGTTGGCTTTGGGTTGTATAAGGAGGATCAAAAC AACAGAGGAAATGCTGACTTTCTAGCTTTGCATGACACCTGGAGCAATGCACTGTACCTGCCTCACTCCTGTCCAGTGGTCAGGTTTCCCCTGACCTTCC CTCACCCCCAGAAACACTTGCTTACAGACCGAAACTGGCATCTTACTCTTGGCACCTTGACTTGCACCCTCTGAGGTTCCAACTCAGTCATTCTTTGTCC AGCAGAGGAGAATCAGAAATGAGCCCTTCAGGATTAATCCTCTTGCACCAGCTCTCAGAGAAATGCTGGGTATCCCTGTCCTTGTCCCTATCTGTCCATC CTGGGGCCTGGTAATGGCCACAGTTATTGTTTTAAATGCCAACACTGTCTTCTCATGTTCTTCCGTGGGGCATTGATTAATGAGCATTTGTTGGCTCCTA AAAATTAGACAATCCATTCTCTTGAAA

refseq_ADD2.F1 (forward primer)
refseq_ADD2.R1 (reverse primer)
Single exon skipping

Frame 0

ISSQPRAGNGFNSDGRAVRD*REPEPFVKELRR RWPVIPAAAEPLHCWGISQQL*RARAAAWAENAA LQISWVDFLSAPHPPNP*NNKTNPQWPTGDS*D AAQEFPPGCLRLCRCGRHP*EWS*GVQTEQ*TE GALDRAGPASRVPGANCKPTGKMSEETVPEAASP PPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDF NLMEQKKRVTMILQSPSFREELEGLIQEQMKKG NNSSNIWALRQIADFMASTSHAVFPTSSMNVSMM TPINDLHTADSLNLAKGERLMRCKISSVYRLLD LYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCS EVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLH SAIYAARPDVRCIIHLHTPATAAVSAMKWGLLP VSHNALLVGDMAYYDFNGEMEQEADRINLQKCL GPTCKILVLRNHGVVALGDTVEEAFYKIFHLQAA CEIQVSALSSAGGVENLILLEQEKHRPHEVGSV QWAGSTFGPMQKSRLGEHEFEALMRMLDNLGYR TGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEED GAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNV ADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIR IENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKS AGPQSQLLASVIAEKSRSPSTESQLMSKGDEDT KDDSEETVPNPFSQLTDQELEEYKKEVERKKLE LDETGQEREPGSGPAVCEFFSVALHIWSNILERK KLPQKSLAHLQSLHLLLQCRAQRRRQRQRAL*S LLPSL*RKVLRRQKQAKPPPQSPKQPSRKGWWS TGGRRSRRQRKSSAKA*AR*PPVLTRMLIPLRTK PSRSPAAPCPQRAHLPSLPQRRKRNSEPPPS*K RAKRRRKWSPDS*HPWAPSCLLSLLPFPSPISV PASTGLRRDRVGPWTTFGRGT*RSPDQPFVLQLP KRNQVTCPRSHS*LAAEPALEFRSPDFQSSAPS TTQHCLVVGCLCLDAVHQSEPRARRPEMGRELS QAQTKSEVKASPE*GPFLPRNPISCGWSYLYI*K SLLFSTLGPCPAAQSD*PN*PLQQKVIFVPKG* WLSLYYPKH*P*AFFMEPLE*WMEEL*EVVGIG ASHVS*GLGMVSST*EARNLTPLNCASQALQN*N QI*HRKKLFNAQGRNLGKLKSSVGFGLYKEDQN NRGNADFLALHDTWSNALYLPHSCPVVRFPLTF PHPQKHLLTDRNWHLTLGTLTCTL*GSNSVILCP AEENQK*ALQD*SSCTSSQRNAGYPCPCPYLSI LGPGNGHSYCFKCQHCLLMFFRGALINEHLLAP KN*TIHSLE

Frame 1

FPPSLVREMALILTAGL*GTSGNPSLLSRNCGV GGQSSPPPRSRCTAGGSPSSSDERGLQHGQKTL PCRLAGWIF*AHPTPQTHKITKPTRSGRPEIAKM PRRSFHLDV*GCVDVAGTLESGARGCRLSSEQK EPWTGLGQPPEFQERIANPPGK*AKRRSPRLPR RRPRRGSLTLTASQRTTPSTCAFATGRRTCGRTS T*WSRRSASP*SCRVPLSGRSWKASSRSR*RRG TTPPTSGPCDRSRTSWPAPPTQSSRHLP*MSP* *RLSMTSTQLTP*TWPKGSGSCGARSAVSTDSWT SMAGPS*VTPMSR*ESARSRTTS*SALREFLAV KSQRPA*SR*TFWERWWRRAAAASQWTPQASVC TRPSMQRGPTCAASSTCTHRPQQRCRP*SGASCL SPTMPCWWGTWPIMTSMGKWSRKPIGSTCRSAL DPPARSWC*ETMEWLLWVTR*RRHFTRSSTCRL HVRYRCRLCPVPGEWRTSSSWSRRSTGPMRWAPC SGPGAPLGLCRRVGWGSMSLRPS*GCWTTWATE QVTRIATPLFKRKPNTKVRWRFQPRSQPSCLRR TVPRCPPCDSMPRSSRRRRPAGSIRPTPTCGSMW PMRSRGAWAAPDPRPRG*RLTRWRNPAVACRFA SKTQTNLCLSILTPRKYWR*GTRFENKTDKM*S QRGLSPSSWRASLPRRAEARLQRAS*CPRETRIP KTIQRRRCPTPSANSLTRSWRSTRKRWRGRN*N LMRQDRNESQALVRPCASSSALPSTSGVTYWRE RNCPRRAWLTCKVCTCFSSAEPSEGGRDKEPFSL SFQVFRGRY*EDRNKQSRHHRARNNPAGRGGGQ REGGGADGRGNPQQRPEPDDHQC*HGC*YL*GQ NRVGHQRPHVPRGLTFQVSLKEEKEIPNPLLPEK EQKEGESGVLIHDTLGLPPASSLSSPSLLPSLS LQAQG*GGIE*DPGPHSEGELRDHPTNPSFYSC PREIR*LAQGHTAS*RQSLHSNSGLLTSSPVLLL LHNTA*LWAAFVWMLSTNLSLGQEGQKWAVSSH RLRLNQRSRLPLSKVHFFPGIQSPVDGAISTFK NLFSFPLWVPALLLKVTSQIDPSNRK*SLFPRAD GLACTTPNINPELSSWNLLNDGWKSYKRW*A*G QAM*AEDWGWFHQHKRPGT*PL*IVHLRHFKTK TKFSIGKSCLMLRAEIWGS*NPLLALGCIRRIKT TEEMLTF*LCMTPGAMHCTCLTPVQWSGFP*PS LTPRNTCLQTETGILLLAP*LAPSEVPTQSFFV QQRRIRNEPFRINPLAPALREMLGIPVLVPICPS WGLVMATVIVLNANTVFSCSSVGH*LMSICWLL KIRQSILLK

Frame 2

FLPASCGKWL*F*RQGCEGLAGTRAFCQGTAAS VASHPRRRGAAALLGDLPAALTSAGCSMGRKRC PAD*LGGFFKRTPPPKPIK*QNQPAVADRR*LR CRAGVSTWMFEVV*MWPAPLRVELGGAD*AVNRR SLGQGWASLPSSRSELQTHRENERRDGPRGCLA AAPAGAALL*PLLRGRPRVHAPSQPGGGPAAGL QPDGAEEARHHDPAESLFQGGAGRPHPGADEEGE QLLQHLGPATDRGLHGQHLPRSLPDIFHECLHD DAYQ*PPHS*LPEPGQRGAAHAVQDQQCLPTPG PLWLGPAE*HLCHVESQQGAGPLPDQP*GSFLQ* SHSVQPDQGEHSGRGGGEGQQLLPSGHHRLLSA LGHLCSEARRALHHPPAHTGHSSGVGHEVGPPA CLPQCPAGGGHGLL*LQWGNGAGSRSDQPAEVPW THLQDPGAKKPWSGCSG*HGRGGILQDLPPAGC M*DTGVGSVQCRGSGEPHPPGAGEAPAP*GGLR AVGREHLWAYAEESAGGA*V*GPHEDAGQPGLQN RLHVSPPLCSRENQTQK*GGDSSHGHSLRV*GG RCPGARPATACPEAAEGEDPLAQYAQHLPAGQC GR*GPEEHGQPPTQDHVDEG*RGGEIQQWHADSH RKPKPICASLY*PPGSTGDEEQDSRTKPTRCEV SGASVPAPGERHCREEPKPVYREPADVQGRRGY QRRFRGDGAQPLQPTH*PGVGGVQERGGEEETRT **DRTGTRARLWSGRVRVLQRCPPHLE*HIGEK ETAPEEPGSPAKSAPASPVQSPAKEAETKSPLV SPSKSLEEGTKKTETSKAATTEPETTQPEGVVVN GREEEQTAEEILSKGLSQMTTSADTDVDTSKDK TESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLK KSKKKEKVES*FMTPLGSLLPPLSPPLPFSHLCP CKHRAKEG*SRTLDHIRKGNLEITRPTLRFTVA QEKSGDLPKVTQLVSGRACTRIQVS*LPVQCSF YYTTLPSCGLPLFGCCPPI*A*GKKARNGP*ALT GSD*IRGQGFP*VRSISSQESNLLWMELSLHLK ISSLFHFGSLPCCSK*LAKLTPPTESNLCSQGL MA*LVLPQTLTLSFLHGTS*MMDGRAIRGGRHRG KPCKLRIGDGFINIRGQELDPFELCISGTSKLK PNLA*EKVV*CSGQKFGEVEILCWLWVV*GGSK QQRKC*LSSFA*HLEQCTVPASLLSSGQVSPDLP SPPETLAYRPKLASYSWHLDLHPLRFQLSHSLS SRGESEMSPSGLILLHQLSEKCWVSLSLSLSVH PGAW*WPQLLF*MPTLSSHVLPWGID**AFVGS* KLDNPFS*