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Sequences

Sequence NM_001011722

GTGTGTAGCTGGGACGGTGCTGGTCTGAGCTGGACCTTGTCTGATGGCTTCCTCCAACCCTCCTCCACAGCCTGCCATAGGAGATCAGCTGGTTCCAGGA
GTCCCAGGCCCCTCCTCTGAGGCAGAGGACGACCCAGGAGAGGCGTTTGAGTTTGATGACAGTGATGATGAAGAGGACACCAGCGCAGCCCTGGGCGTCC
CCAGCCTTGCTCCTGAGAGGGACACAGACCCCCCACTGATCCACTTGGACTCCATCCCTGTCACTGACCCAGACCCAGCAGCTGCTCCACCCGGCACAGG
GGTGCCAGCCTGGGTGAGCAATGGGGATGCAGCGGACGCAGCCTTCTCCGGGGCCCGGCACTCCAGCTGGAAGCGGAAGAGTTCCCGTCGCATTGACCGG
TTCACTTTCCCCGCCCTGGAAGAGGATGTGATTTATGACGACGTCCCCTGCGAGAGCCCAGATGCGCATCAGCCCGGGGCAGAGAGGAACCTGCTCTACG
AGGATGCGCACCGGGCTGGGGCCCCTCGGCAGGCGGAGGACCTAGGCTGGAGCTCCAGTGAGTTCGAGAGCTACAGCGAGGACTCGGGGGAGGAGGCCAA
GCCGGAGGTCGAGGTCGAGCCCGCCAAGCACCGAGTGTCCTTCCAGCCCAAGATGACCCAGCTCATGAAGGCCGCCAAGAGCGGGACCAAGGATGGGCTG
GAGAAGACACGGATGGCCGTGATGCGCAAAGTCTCCTTCCTGCACAGGAAGGACGTCCTCGGTGACTCGGAGGAGGAGGACATGGGGCTCCTGGAGGTCA
GCGTTTCGGACATCAAGCCCCCAGCCCCAGAGCTGGGCCCCATGCCAGAGGGCCTGAGCCCTCAGCAGGTGGTCCGGAGGCATATCCTGGGCTCCATCGT
GCAGAGCGAAGGCAGCTACGTGGAGTCTCTGAAGCGGATACTCCAGGACTACCGCAACCCCCTGATGGAGATGGAGCCCAAGGCGCTGAGCGCCCGCAAG
TGCCAGGTGGTGTTCTTCCGCGTGAAGGAGATCCTGCACTGCCACTCCATGTTCCAGATCGCCCTGTCCTCCCGCGTGGCTGAGTGGGATTCCACCGAGA
AGATCGGGGACCTCTTCGTGGCCTCGTTTTCCAAGTCCATGGTGCTAGATGTGTACAGTGACTACGTGAACAACTTCACCAGTGCCATGTCCATCATCAA
GAAGGCCTGCCTCACCAAGCCTGCCTTCCTCGAGTTCCTCAAGCGACGGCAGGTGTGCAGCCCAGACCGTGTCACCCTCTACGGGCTGATGGTCAAGCCC
ATCCAGAGGTTCCCACAGTTCATACTCCTGCTTCAGGACATGCTGAAGAACACCCCCAGGGGCCATCCGGACAGGCTGTCGCTGCAGCTGGCCCTCACAG
AGCTGGAGACGCTGGCTGAGAAGCTGAACGAGCAGAAGCGGCTGGCTGACCAGGTGGCTGAGATCCAGCAGCTGACCAAGAGCGTCAGTGACCGCAGCAG
CCTCAACAAGCTGTTGACCTCAGGCCAGCGGCAGCTGCTCCTGTGTGAGACGTTGACGGAGACCGTGTACGGTGACCGCGGGCAGCTAATTAAGTCCAAG
GAGCGTCGGGTCTTCCTGCTCAACGACATGCTTGTCTGTGCCAACATCAACTTCAAGCCTGCCAACCACAGGGGCCAGCTGGAGATCAGCAGCCTGGTGC
CCCTGGGGCCCAAGTATGTGGTGAAGTGGAACACGGCGCTGCCCCAGGTGCAGGTGGTGGAGGTGGGCCAGGACGGTGGCACCTATGACAAGGACAATGT
GCTCATCCAGCACTCAGGCGCCAAGAAGGCCTCTGCCTCAGGGCAGGCTCAGAATAAGGTGTACCTCGGCCCCCCACGCCTCTTCCAGGAGCTGCAGGAC
CTGCAGAAGGACCTGGCCGTGGTGGAGCAGATCACGCTTCTCATCAGCACGCTGCACGGCACCTACCAGAACCTGAACATGACTGTGGCTCAAGACTGGT
GCCTGGCCCTGCAGAGGCTGATGCGGGTGAAGGAGGAAGAGATCCACTCGGCCAACAAGTGCCGTCTCAGGCTCCTGCTTCCTGGGAAACCCGACAAGTC
CGGCCGCCCCATTAGCTTCATGGTGGTTTTCATCACCCCCAACCCCCTGAGCAAGATTTCCTGGGTCAACAGGTTACATTTGGCCAAAATCGGACTCCGG
GAGGAGAACCAGCCAGGCTGGCTATGCCCGGATGAGGACAAGAAGAGCAAAGCCCCATTCTGGTGCCCGATCCTGGCCTGCTGCATCCCTGCCTTCTCCT
CCCGGGCACTCAGCCTGCAGCTTGGGGCCCTGGTCCACAGTCCTGTCAACTGTCCCCTGCTGGGTTTCTCAGCAGTCAGCACCTCCCTTCCACAGGGCTA
CCTCTGGGTCGGGGGCGGACAGGAAGGCGCAGGGGGCCAGGTGGAAATCTTTTCCTTGAACCGGCCCTCGCCCCGCACCGTCAAGTCCTTCCCACTGGCA
GCCCCTGTGCTCTGCATGGAGTATATCCCGGAGCTGGAGGAGGAGGCGGAGAGCAGAGACGAGAGCCCGACAGTTGCTGACCCCTCGGCCACGGTGCATC
CAACCATCTGCCTCGGGCTCCAGGATGGCAGCATCCTCCTCTACAGCAGTGTGGACACTGGCACCCAGTGCCTGGTGAGCTGCAGGAGCCCAGGTCTGCA
GCCTGTGCTCTGCCTGCGACACAGCCCCTTCCACCTGCTCGCTGGCCTGCAGGATGGGACCCTTGCTGCTTACCCTCGGACCAGCGGAGGTGTCCTGTGG
GACCTGGAGAGCCCTCCCGTGTGCCTGACTGTGGGGCCCGGGCCTGTCCGCACCCTGTTGAGCCTGGAGGATGCCGTGTGGGCCAGCTGTGGGCCCTGGG
TCACTGTCCTGGAAGCCACCACCCTGCAGCCTCAGCAAAGCTTCGAGGCGCACCAGGACGAGGCAGTGAGCGTGACACACATGGTGAAGGCGGGCAGCGG
CGTCTGGATGGCCTTCTCCTCCGGCACCTCCATCCGCCTCTTCCACACTGAGACCCTGGAGCATCTGCAAGAGATCAACATCGCCACCAGGACCACCTTC
CTCCTGCCAGGCCAGAAGCACTTGTGTGTCACCAGCCTCCTGATCTGCCAGGGTCTGCTCTGGGTGGGCACTGACCAGGGTGTCATCGTCCTGCTGCCCG
TGCCTCGGCTGGAAGGCATCCCCAAGATCACAGGGAAAGGCATGGTCTCACTCAACGGGCACTGTGGGCCTGTGGCCTTCCTGGCTGTGGCTACCAGCAT
CCTGGCCCCTGACATCCTGCGGAGTGACCAGGAGGAGGCTGAGGGGCCCCGGGCTGAGGAGGACAAGCCAGACGGGCAGGCACACGAGCCCATGCCCGAT
AGCCACGTGGGCCGAGAGCTGACCCGCAAGAAGGGCATCCTCTTGCAGTACCGCCTGCGCTCCACCGCACACCTCCCGGGCCCGCTGCTCTCCATGCGGG
AGCCGGCGCCTGCTGATGGCGCAGCTTTGGAGCACAGCGAGGAGGACGGCTCCATTTACGAGATGGCCGACGACCCCGACATCTGGGTGCGCAGCCGGCC
CTGCGCCCGCGACGCCCACCGCAAGGAGATTTGCTCTGTGGCCATCATCTCCGGCGGGCAGGGCTACCGCAACTTTGGCAGCGCTCTGGGCAGCAGTGGG
AGGCAGGCCCCGTGTGGGGAGACGGACAGCACCCTCCTCATCTGGCAGGTGCCCTTGATGCTATAGCGCCTCCCCTCTCCCCTCAGAGGGCACAGCTGCA
GGCCTGACCAAGGCCACGCCCGGCTCTCGTGCTCTAGGACCTGCACGGGACTTGTGGATGGGCCTGGACTCTCCAGAAACTACTTGGGCAGAGCAAAGGA
AAACCTCTTGTTTTAAAAAAATTTTTTTCAGAGTGTTTTGGGGAGGAGTTTTAGGGCTTGGGGAGAGGGAGGACACATCTGGAGGAAATGGCCTTCTTTT
TAAAAGCAAAAAACACAAAACCTCACAACTGCCTGGCAAGCCCAGTATCACTTGTTTGGGCCCTAGCGGGACTCCAAGGCAGCCACACGCCCCTCCTGGA
AGGGTGTGTGCGTGTGAGTGTGTGCGAGTGTGTGGGCTGGTGTGTGAATATCTATAAATAAGTATATATGGTGTATATTATATGTGTATAAATAAAGTCT
GTACATATTGGAGCTCTGGGAGATGCTGGAATAAAAGACAAGAGTTACATCTGGACTTGGA
  • refseq_ARHGEF10L.F1 (forward primer)
  • refseq_ARHGEF10L.R1 (reverse primer)
  • Single exon skipping

Frame 0

VCSWDGAGLSWTLSDGFLQPSSTACHRRSAGSR
SPRPLL*GRGRPRRGV*V**Q***RGHQRSPGRP
QPCS*EGHRPPTDPLGLHPCH*PRPSSCSTRHR
GASLGEQWGCSGRSLLRGPALQLEAEEFPSH*P
VHFPRPGRGCDL*RRPLREPRCASARGREEPALR
GCAPGWGPSAGGGPRLELQ*VRELQRGLGGGGQ
AGGRGRARQAPSVLPAQDDPAHEGRQERDQGWA
GEDTDGRDAQSLLPAQEGRPR*LGGGGHGAPGGQ
RFGHQAPSPRAGPHARGPEPSAGGPEAYPGLHR
AERRQLRGVSEADTPGLPQPPDGDGAQGAERPQ
VPGGVLPREGDPALPLHVPDRPVLPRG*VGFHRE
DRGPLRGLVFQVHGARCVQ*LREQLHQCHVHHQ
EGLPHQACLPRVPQATAGVQPRPCHPLRADGQA
HPEVPTVHTPASGHAEEHPQGPSGQAVAAAGPHR
AGDAG*EAERAEAAG*PGG*DPAADQERQ*PQQ
PQQAVDLRPAAAAPV*DVDGDRVR*PRAAN*VQ
GASGLPAQRHACLCQHQLQACQPQGPAGDQQPGA
PGAQVCGEVEHGAAPGAGGGGGPGRWHL*QGQC
AHPALRRQEGLCLRAGSE*GVPRPPTPLPGAAG
PAEGPGRGGADHASHQHAARHLPEPEHDCGSRLV
PGPAEADAGEGGRDPLGQQVPSQAPASWETRQV
RPPH*LHGGFHHPQPPEQDFLGQQVTFGQNRTP
GGEPARLAMPG*GQEEQSPILVPDPGLLHPCLLL
PGTQPAAWGPGPQSCQLSPAGFLSSQHLPSTGL
PLGRGRTGRRRGPGGNLFLEPALAPHRQVLPTG
SPCALHGVYPGAGGGGGEQRREPDSC*PLGHGAS
NHLPRAPGWQHPPLQQCGHWHPVPGELQEPRSA
ACALPATQPLPPARWPAGWDPCCLPSDQRRCPV
GPGEPSRVPDCGARACPHPVEPGGCRVGQLWALG
HCPGSHHPAASAKLRGAPGRGSERDTHGEGGQR
RLDGLLLRHLHPPLPH*DPGASARDQHRHQDHL
PPARPEALVCHQPPDLPGSALGGH*PGCHRPAAR
ASAGRHPQDHRERHGLTQRALWACGLPGCGYQH
PGP*HPAE*PGGG*GAPG*GGQARRAGTRAHAR
*PRGPRADPQEGHPLAVPPALHRTPPGPAALHAG
AGAC*WRSFGAQRGGRLHLRDGRRPRHLGAQPA
LRPRRPPQGDLLCGHHLRRAGLPQLWQRSGQQW
EAGPVWGDGQHPPHLAGALDAIAPPLSPQRAQLQ
A*PRPRPALVL*DLHGTCGWAWTLQKLLGQSKG
KPLVLKKFFSECFGEEF*GLGRGRTHLEEMAFF
LKAKNTKPHNCLASPVSLVWALAGLQGSHTPLLE
GCVRVSVCECVGWCVNIYK*VYMVYIICV*IKS
VHIGALGDAGIKDKSYIWTW

Frame 1

CVAGTVLV*AGPCLMASSNPPPQPAIGDQLVPG
VPGPSSEAEDDPGEAFEFDDSDDEEDTSAALGV
PSLAPERDTDPPLIHLDSIPVTDPDPAAAPPGTG
VPAWVSNGDAADAAFSGARHSSWKRKSSRRIDR
FTFPALEEDVIYDDVPCESPDAHQPGAERNLLY
EDAHRAGAPRQAEDLGWSSSEFESYSEDSGEEAK
PEVEVEPAKHRVSFQPKMTQLMKAAKSGTKDGL
EKTRMAVMRKVSFLHRKDVLGDSEEEDMGLLEV
SVSDIKPPAPELGPMPEGLSPQQVVRRHILGSIV
QSEGSYVESLKRILQDYRNPLMEMEPKALSARK
CQVVFFRVKEILHCHSMFQIALSSRVAEWDSTE
KIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIK
KACLTKPAFLEFLKRRQVCSPDRVTLYGLMVKP
IQRFPQFILLLQDMLKNTPRGHPDRLSLQLALT
ELETLAEKLNEQKRLADQVAEIQQLTKSVSDRSS
LNKLLTSGQRQLLLCETLTETVYGDRGQLIKSK
ERRVFLLNDMLVCANINFKPANHRGQLEISSLV
PLGPKYVVKWNTALPQVQVVEVGQDGGTYDKDNV
LIQHSGAKKASASGQAQNKVYLGPPRLFQELQD
LQKDLAVVEQITLLISTLHGTYQNLNMTVAQDW
CLALQRLMRVKEEEIHSANKCRLRLLLPGKPDKS
GRPISFMVVFITPNPLSKISWVNRLHLAKIGLR
EENQPGWLCPDEDKKSKAPFWCPILACCIPAFS
SRALSLQLGALVHSPVNCPLLGFSAVSTSLPQGY
LWVGGGQEGAGGQVEIFSLNRPSPRTVKSFPLA
APVLCMEYIPELEEEAESRDESPTVADPSATVH
PTICLGLQDGSILLYSSVDTGTQCLVSCRSPGLQ
PVLCLRHSPFHLLAGLQDGTLAAYPRTSGGVLW
DLESPPVCLTVGPGPVRTLLSLEDAVWASCGPW
VTVLEATTLQPQQSFEAHQDEAVSVTHMVKAGSG
VWMAFSSGTSIRLFHTETLEHLQEINIATRTTF
LLPGQKHLCVTSLLICQGLLWVGTDQGVIVLLP
VPRLEGIPKITGKGMVSLNGHCGPVAFLAVATSI
LAPDILRSDQEEAEGPRAEEDKPDGQAHEPMPD
SHVGRELTRKKGILLQYRLRSTAHLPGPLLSMR
EPAPADGAALEHSEEDGSIYEMADDPDIWVRSRP
CARDAHRKEICSVAIISGGQGYRNFGSALGSSG
RQAPCGETDSTLLIWQVPLML*RLPSPLRGHSC
RPDQGHARLSCSRTCTGLVDGPGLSRNYLGRAKE
NLLF*KNFFQSVLGRSFRAWGEGGHIWRKWPSF
*KQKTQNLTTAWQAQYHLFGP*RDSKAATRPSW
KGVCV*VCASVWAGV*ISINKYIWCILYVYK*SL
YILELWEMLE*KTRVTSGLG

Frame 2

V*LGRCWSELDLV*WLPPTLLHSLP*EISWFQE
SQAPPLRQRTTQERRLSLMTVMMKRTPAQPWAS
PALLLRGTQTPH*STWTPSLSLTQTQQLLHPAQ
GCQPG*AMGMQRTQPSPGPGTPAGSGRVPVALTG
SLSPPWKRM*FMTTSPARAQMRISPGQRGTCST
RMRTGLGPLGRRRT*AGAPVSSRATARTRGRRP
SRRSRSSPPSTECPSSPR*PSS*RPPRAGPRMGW
RRHGWP*CAKSPSCTGRTSSVTRRRRTWGSWRS
AFRTSSPQPQSWAPCQRA*ALSRWSGGISWAPS
CRAKAATWSL*SGYSRTTATP*WRWSPRR*APAS
ARWCSSA*RRSCTATPCSRSPCPPAWLSGIPPR
RSGTSSWPRFPSPWC*MCTVTT*TTSPVPCPSS
RRPASPSLPSSSSSSDGRCAAQTVSPSTG*WSSP
SRGSHSSYSCFRTC*RTPPGAIRTGCRCSWPSQ
SWRRWLRS*TSRSGWLTRWLRSSS*PRASVTAA
ASTSC*PQASGSCSCVRR*RRPCTVTAGS*LSPR
SVGSSCSTTCLSVPTSTSSLPTTGASWRSAAWC
PWGPSMW*SGTRRCPRCRWWRWARTVAPMTRTM
CSSSTQAPRRPLPQGRLRIRCTSAPHASSRSCRT
CRRTWPWWSRSRFSSARCTAPTRT*T*LWLKTG
AWPCRG*CG*RRKRSTRPTSAVSGSCFLGNPTS
PAAPLASWWFSSPPTP*ARFPGSTGYIWPKSDSG
RRTSQAGYARMRTRRAKPHSGARSWPAASLPSP
PGHSACSLGPWSTVLSTVPCWVSQQSAPPFHRA
TSGSGADRKAQGARWKSFP*TGPRPAPSSPSHWQ
PLCSAWSISRSWRRRRRAETRARQLLTPRPRCI
QPSASGSRMAASSSTAVWTLAPSAW*AAGAQVC
SLCSACDTAPSTCSLACRMGPLLLTLGPAEVSCG
TWRALPCA*LWGPGLSAPC*AWRMPCGPAVGPG
SLSWKPPPCSLSKASRRTRTRQ*A*HTW*RRAA
ASGWPSPPAPPSASSTLRPWSICKRSTSPPGPPS
SCQARSTCVSPAS*SARVCSGWALTRVSSSCCP
CLGWKASPRSQGKAWSHSTGTVGLWPSWLWLPA
SWPLTSCGVTRRRLRGPGLRRTSQTGRHTSPCPI
ATWAES*PARRASSCSTACAPPHTSRARCSPCG
SRRLLMAQLWSTARRTAPFTRWPTTPTSGCAAG
PAPATPTARRFALWPSSPAGRATATLAALWAAVG
GRPRVGRRTAPSSSGRCP*CYSASPLPSEGTAA
GLTKATPGSRALGPARDLWMGLDSPETTWAEQR
KTSCFKKIFFRVFWGGVLGLGEREDTSGGNGLLF
KSKKHKTSQLPGKPSITCLGPSGTPRQPHAPPG
RVCACECVRVCGLVCEYL*ISIYGVYYMCINKV
CTYWSSGRCWNKRQELHLDL

Sequence NM_018125

GCGCCGTCCCGGCCATGGGCGCCCGCGGCGGCCTGCGGAGCTGGAGGCGCGGCGCCGGCCGCCAGGCGCCTTTGTGAGCGGCGCGGACGACAAAGGCGCG
GGCCCGGGCAGCCGAGGTGTGTAGCTGGGACGGTGCTGGTCTGAGCTGGACCTTGTCTGATGGCTTCCTCCAACCCTCCTCCACAGCCTGCCATAGGAGA
TCAGCTGGTTCCAGGAGTCCCAGGCCCCTCCTCTGAGGCAGAGGACGACCCAGGAGAGGCGTTTGAGTTTGATGACAGTGATGATGAAGAGGACACCAGC
GCAGCCCTGGGCGTCCCCAGCCTTGCTCCTGAGAGGGACACAGACCCCCCACTGATCCACTTGGACTCCATCCCTGTCACTGACCCAGACCCAGCAGCTG
CTCCACCCGGCACAGGGGTGCCAGCCTGGGTGAGCAATGGGGATGCAGCGGACGCAGCCTTCTCCGGGGCCCGGCACTCCAGCTGGAAGCGGAAGAGTTC
CCGTCGCATTGACCGGTTCACTTTCCCCGCCCTGGAAGAGGATGTGATTTATGACGACGTCCCCTGCGAGAGCCCAGATGCGCATCAGCCCGGGGCAGAG
AGGAACCTGCTCTACGAGGATGCGCACCGGGCTGGGGCCCCTCGGCAGGCGGAGGACCTAGGCTGGAGCTCCAGTGAGTTCGAGAGCTACAGCGAGGACT
CGGGGGAGGAGGCCAAGCCGGAGGTCGAGGTCGAGCCCGCCAAGCACCGAGTGTCCTTCCAGCCCAAGCTTTCTCCAGACCTGACTAGGCTAAAGGAGAG
ATACGCCAGGACTAAGAGAGACATCTTGGCTTTGAGAGTTGGGGGGAGAGACATGCAGGAGCTGAAGCACAAGTACGATTGTAAG
ATGACCCAGCTCATG
AAGGCCGCCAAGAGCGGGACCAAGGATGGGCTGGAGAAGACACGGATGGCCGTGATGCGCAAAGTCTCCTTCCTGCACAGGAAGGACGTCCTCGGTGACT
CGGAGGAGGAGGACATGGGGCTCCTGGAGGTCAGCGTTTCGGACATCAAGCCCCCAGCCCCAGAGCTGGGCCCCATGCCAGAGGGCCTGAGCCCTCAGCA
GGTGGTCCGGAGGCATATCCTGGGCTCCATCGTGCAGAGCGAAGGCAGCTACGTGGAGTCTCTGAAGCGGATACTCCAGGACTACCGCAACCCCCTGATG
GAGATGGAGCCCAAGGCGCTGAGCGCCCGCAAGTGCCAGGTGGTGTTCTTCCGCGTGAAGGAGATCCTGCACTGCCACTCCATGTTCCAGATCGCCCTGT
CCTCCCGCGTGGCTGAGTGGGATTCCACCGAGAAGATCGGGGACCTCTTCGTGGCCTCGTTTTCCAAGTCCATGGTGCTAGATGTGTACAGTGACTACGT
GAACAACTTCACCAGTGCCATGTCCATCATCAAGAAGGCCTGCCTCACCAAGCCTGCCTTCCTCGAGTTCCTCAAGCGACGGCAGGTGTGCAGCCCAGAC
CGTGTCACCCTCTACGGGCTGATGGTCAAGCCCATCCAGAGGTTCCCACAGTTCATACTCCTGCTTCAGGACATGCTGAAGAACACCCCCAGGGGCCATC
CGGACAGGCTGTCGCTGCAGCTGGCCCTCACAGAGCTGGAGACGCTGGCTGAGAAGCTGAACGAGCAGAAGCGGCTGGCTGACCAGGTGGCTGAGATCCA
GCAGCTGACCAAGAGCGTCAGTGACCGCAGCAGCCTCAACAAGCTGTTGACCTCAGGCCAGCGGCAGCTGCTCCTGTGTGAGACGTTGACGGAGACCGTG
TACGGTGACCGCGGGCAGCTAATTAAGTCCAAGGAGCGTCGGGTCTTCCTGCTCAACGACATGCTTGTCTGTGCCAACATCAACTTCAAGCCTGCCAACC
ACAGGGGCCAGCTGGAGATCAGCAGCCTGGTGCCCCTGGGGCCCAAGTATGTGGTGAAGTGGAACACGGCGCTGCCCCAGGTGCAGGTGGTGGAGGTGGG
CCAGGACGGTGGCACCTATGACAAGGACAATGTGCTCATCCAGCACTCAGGCGCCAAGAAGGCCTCTGCCTCAGGGCAGGCTCAGAATAAGGTGTACCTC
GGCCCCCCACGCCTCTTCCAGGAGCTGCAGGACCTGCAGAAGGACCTGGCCGTGGTGGAGCAGATCACGCTTCTCATCAGCACGCTGCACGGCACCTACC
AGAACCTGAACATGACTGTGGCTCAAGACTGGTGCCTGGCCCTGCAGAGGCTGATGCGGGTGAAGGAGGAAGAGATCCACTCGGCCAACAAGTGCCGTCT
CAGGCTCCTGCTTCCTGGGAAACCCGACAAGTCCGGCCGCCCCATTAGCTTCATGGTGGTTTTCATCACCCCCAACCCCCTGAGCAAGATTTCCTGGGTC
AACAGGTTACATTTGGCCAAAATCGGACTCCGGGAGGAGAACCAGCCAGGCTGGCTATGCCCGGATGAGGACAAGAAGAGCAAAGCCCCATTCTGGTGCC
CGATCCTGGCCTGCTGCATCCCTGCCTTCTCCTCCCGGGCACTCAGCCTGCAGCTTGGGGCCCTGGTCCACAGTCCTGTCAACTGTCCCCTGCTGGGTTT
CTCAGCAGTCAGCACCTCCCTTCCACAGGGCTACCTCTGGGTCGGGGGCGGACAGGAAGGCGCAGGGGGCCAGGTGGAAATCTTTTCCTTGAACCGGCCC
TCGCCCCGCACCGTCAAGTCCTTCCCACTGGCAGCCCCTGTGCTCTGCATGGAGTATATCCCGGAGCTGGAGGAGGAGGCGGAGAGCAGAGACGAGAGCC
CGACAGTTGCTGACCCCTCGGCCACGGTGCATCCAACCATCTGCCTCGGGCTCCAGGATGGCAGCATCCTCCTCTACAGCAGTGTGGACACTGGCACCCA
GTGCCTGGTGAGCTGCAGGAGCCCAGGTCTGCAGCCTGTGCTCTGCCTGCGACACAGCCCCTTCCACCTGCTCGCTGGCCTGCAGGATGGGACCCTTGCT
GCTTACCCTCGGACCAGCGGAGGTGTCCTGTGGGACCTGGAGAGCCCTCCCGTGTGCCTGACTGTGGGGCCCGGGCCTGTCCGCACCCTGTTGAGCCTGG
AGGATGCCGTGTGGGCCAGCTGTGGGCCCTGGGTCACTGTCCTGGAAGCCACCACCCTGCAGCCTCAGCAAAGCTTCGAGGCGCACCAGGACGAGGCAGT
GAGCGTGACACACATGGTGAAGGCGGGCAGCGGCGTCTGGATGGCCTTCTCCTCCGGCACCTCCATCCGCCTCTTCCACACTGAGACCCTGGAGCATCTG
CAAGAGATCAACATCGCCACCAGGACCACCTTCCTCCTGCCAGGCCAGAAGCACTTGTGTGTCACCAGCCTCCTGATCTGCCAGGGTCTGCTCTGGGTGG
GCACTGACCAGGGTGTCATCGTCCTGCTGCCCGTGCCTCGGCTGGAAGGCATCCCCAAGATCACAGGGAAAGGCATGGTCTCACTCAACGGGCACTGTGG
GCCTGTGGCCTTCCTGGCTGTGGCTACCAGCATCCTGGCCCCTGACATCCTGCGGAGTGACCAGGAGGAGGCTGAGGGGCCCCGGGCTGAGGAGGACAAG
CCAGACGGGCAGGCACACGAGCCCATGCCCGATAGCCACGTGGGCCGAGAGCTGACCCGCAAGAAGGGCATCCTCTTGCAGTACCGCCTGCGCTCCACCG
CACACCTCCCGGGCCCGCTGCTCTCCATGCGGGAGCCGGCGCCTGCTGATGGCGCAGCTTTGGAGCACAGCGAGGAGGACGGCTCCATTTACGAGATGGC
CGACGACCCCGACATCTGGGTGCGCAGCCGGCCCTGCGCCCGCGACGCCCACCGCAAGGAGATTTGCTCTGTGGCCATCATCTCCGGCGGGCAGGGCTAC
CGCAACTTTGGCAGCGCTCTGGGCAGCAGTGGGAGGCAGGCCCCGTGTGGGGAGACGGACAGCACCCTCCTCATCTGGCAGGTGCCCTTGATGCTATAGC
GCCTCCCCTCTCCCCTCAGAGGGCACAGCTGCAGGCCTGACCAAGGCCACGCCCGGCTCTCGTGCTCTAGGACCTGCACGGGACTTGTGGATGGGCCTGG
ACTCTCCAGAAACTACTTGGGCAGAGCAAAGGAAAACCTCTTGTTTTAAAAAAATTTTTTTCAGAGTGTTTTGGGGAGGAGTTTTAGGGCTTGGGGAGAG
GGAGGACACATCTGGAGGAAATGGCCTTCTTTTTAAAAGCAAAAAACACAAAACCTCACAACTGCCTGGCAAGCCCAGTATCACTTGTTTGGGCCCTAGC
GGGACTCCAAGGCAGCCACACGCCCCTCCTGGAAGGGTGTGTGCGTGTGAGTGTGTGCGAGTGTGTGGGCTGGTGTGTGAATATCTATAAATAAGTATAT
ATGGTGTATATTATATGTGTATAAATAAAGTCTGTACATATTGGAGCTCTGGGAGATGCTGGAATAAAAGACAAGAGTTACATCTGGACTTGGA
  • refseq_ARHGEF10L.F1 (forward primer)
  • refseq_ARHGEF10L.R1 (reverse primer)
  • Single exon skipping

Frame 0

APSRPWAPAAACGAGGAAPAARRLCERRGRQRR
GPGQPRCVAGTVLV*AGPCLMASSNPPPQPAIGD
QLVPGVPGPSSEAEDDPGEAFEFDDSDDEEDTS
AALGVPSLAPERDTDPPLIHLDSIPVTDPDPAA
APPGTGVPAWVSNGDAADAAFSGARHSSWKRKSS
RRIDRFTFPALEEDVIYDDVPCESPDAHQPGAE
RNLLYEDAHRAGAPRQAEDLGWSSSEFESYSED
SGEEAKPEVEVEPAKHRVSFQPKLSPDLTRLKER
YARTKRDILALRVGGRDMQELKHKYDCK
MTQLM
KAAKSGTKDGLEKTRMAVMRKVSFLHRKDVLGD
SEEEDMGLLEVSVSDIKPPAPELGPMPEGLSPQQ
VVRRHILGSIVQSEGSYVESLKRILQDYRNPLM
EMEPKALSARKCQVVFFRVKEILHCHSMFQIAL
SSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYV
NNFTSAMSIIKKACLTKPAFLEFLKRRQVCSPD
RVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGH
PDRLSLQLALTELETLAEKLNEQKRLADQVAEIQ
QLTKSVSDRSSLNKLLTSGQRQLLLCETLTETV
YGDRGQLIKSKERRVFLLNDMLVCANINFKPAN
HRGQLEISSLVPLGPKYVVKWNTALPQVQVVEVG
QDGGTYDKDNVLIQHSGAKKASASGQAQNKVYL
GPPRLFQELQDLQKDLAVVEQITLLISTLHGTY
QNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRL
RLLLPGKPDKSGRPISFMVVFITPNPLSKISWV
NRLHLAKIGLREENQPGWLCPDEDKKSKAPFWC
PILACCIPAFSSRALSLQLGALVHSPVNCPLLGF
SAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRP
SPRTVKSFPLAAPVLCMEYIPELEEEAESRDES
PTVADPSATVHPTICLGLQDGSILLYSSVDTGTQ
CLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLA
AYPRTSGGVLWDLESPPVCLTVGPGPVRTLLSL
EDAVWASCGPWVTVLEATTLQPQQSFEAHQDEAV
SVTHMVKAGSGVWMAFSSGTSIRLFHTETLEHL
QEINIATRTTFLLPGQKHLCVTSLLICQGLLWV
GTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCG
PVAFLAVATSILAPDILRSDQEEAEGPRAEEDK
PDGQAHEPMPDSHVGRELTRKKGILLQYRLRST
AHLPGPLLSMREPAPADGAALEHSEEDGSIYEMA
DDPDIWVRSRPCARDAHRKEICSVAIISGGQGY
RNFGSALGSSGRQAPCGETDSTLLIWQVPLML*
RLPSPLRGHSCRPDQGHARLSCSRTCTGLVDGPG
LSRNYLGRAKENLLF*KNFFQSVLGRSFRAWGE
GGHIWRKWPSF*KQKTQNLTTAWQAQYHLFGP*
RDSKAATRPSWKGVCV*VCASVWAGV*ISINKYI
WCILYVYK*SLYILELWEMLE*KTRVTSGLG

Frame 1

RRPGHGRPRRPAELEARRRPPGAFVSGADDKGA
GPGSRGV*LGRCWSELDLV*WLPPTLLHSLP*E
ISWFQESQAPPLRQRTTQERRLSLMTVMMKRTPA
QPWASPALLLRGTQTPH*STWTPSLSLTQTQQL
LHPAQGCQPG*AMGMQRTQPSPGPGTPAGSGRV
PVALTGSLSPPWKRM*FMTTSPARAQMRISPGQR
GTCSTRMRTGLGPLGRRRT*AGAPVSSRATART
RGRRPSRRSRSSPPSTECPSSPSFLQT*LG*RR
DTPGLRETSWL*ELGGETCRS*STSTIVR
*PSS*
RPPRAGPRMGWRRHGWP*CAKSPSCTGRTSSVT
RRRRTWGSWRSAFRTSSPQPQSWAPCQRA*ALS
RWSGGISWAPSCRAKAATWSL*SGYSRTTATP*W
RWSPRR*APASARWCSSA*RRSCTATPCSRSPC
PPAWLSGIPPRRSGTSSWPRFPSPWC*MCTVTT
*TTSPVPCPSSRRPASPSLPSSSSSSDGRCAAQT
VSPSTG*WSSPSRGSHSSYSCFRTC*RTPPGAI
RTGCRCSWPSQSWRRWLRS*TSRSGWLTRWLRS
SS*PRASVTAAASTSC*PQASGSCSCVRR*RRPC
TVTAGS*LSPRSVGSSCSTTCLSVPTSTSSLPT
TGASWRSAAWCPWGPSMW*SGTRRCPRCRWWRW
ARTVAPMTRTMCSSSTQAPRRPLPQGRLRIRCTS
APHASSRSCRTCRRTWPWWSRSRFSSARCTAPT
RT*T*LWLKTGAWPCRG*CG*RRKRSTRPTSAV
SGSCFLGNPTSPAAPLASWWFSSPPTP*ARFPGS
TGYIWPKSDSGRRTSQAGYARMRTRRAKPHSGA
RSWPAASLPSPPGHSACSLGPWSTVLSTVPCWV
SQQSAPPFHRATSGSGADRKAQGARWKSFP*TGP
RPAPSSPSHWQPLCSAWSISRSWRRRRRAETRA
RQLLTPRPRCIQPSASGSRMAASSSTAVWTLAP
SAW*AAGAQVCSLCSACDTAPSTCSLACRMGPLL
LTLGPAEVSCGTWRALPCA*LWGPGLSAPC*AW
RMPCGPAVGPGSLSWKPPPCSLSKASRRTRTRQ
*A*HTW*RRAAASGWPSPPAPPSASSTLRPWSIC
KRSTSPPGPPSSCQARSTCVSPAS*SARVCSGW
ALTRVSSSCCPCLGWKASPRSQGKAWSHSTGTV
GLWPSWLWLPASWPLTSCGVTRRRLRGPGLRRTS
QTGRHTSPCPIATWAES*PARRASSCSTACAPP
HTSRARCSPCGSRRLLMAQLWSTARRTAPFTRW
PTTPTSGCAAGPAPATPTARRFALWPSSPAGRAT
ATLAALWAAVGGRPRVGRRTAPSSSGRCP*CYS
ASPLPSEGTAAGLTKATPGSRALGPARDLWMGL
DSPETTWAEQRKTSCFKKIFFRVFWGGVLGLGER
EDTSGGNGLLFKSKKHKTSQLPGKPSITCLGPS
GTPRQPHAPPGRVCACECVRVCGLVCEYL*ISI
YGVYYMCINKVCTYWSSGRCWNKRQELHLDL

Frame 2

AVPAMGARGGLRSWRRGAGRQAPL*AARTTKAR
ARAAEVCSWDGAGLSWTLSDGFLQPSSTACHRR
SAGSRSPRPLL*GRGRPRRGV*V**Q***RGHQ
RSPGRPQPCS*EGHRPPTDPLGLHPCH*PRPSSC
STRHRGASLGEQWGCSGRSLLRGPALQLEAEEF
PSH*PVHFPRPGRGCDL*RRPLREPRCASARGR
EEPALRGCAPGWGPSAGGGPRLELQ*VRELQRGL
GGGGQAGGRGRARQAPSVLPAQAFSRPD*AKGE
IRQD*ERHLGFESWGERHAGAEAQVRL*
DDPAH
EGRQERDQGWAGEDTDGRDAQSLLPAQEGRPR*L
GGGGHGAPGGQRFGHQAPSPRAGPHARGPEPSA
GGPEAYPGLHRAERRQLRGVSEADTPGLPQPPD
GDGAQGAERPQVPGGVLPREGDPALPLHVPDRPV
LPRG*VGFHREDRGPLRGLVFQVHGARCVQ*LR
EQLHQCHVHHQEGLPHQACLPRVPQATAGVQPR
PCHPLRADGQAHPEVPTVHTPASGHAEEHPQGPS
GQAVAAAGPHRAGDAG*EAERAEAAG*PGG*DP
AADQERQ*PQQPQQAVDLRPAAAAPV*DVDGDR
VR*PRAAN*VQGASGLPAQRHACLCQHQLQACQP
QGPAGDQQPGAPGAQVCGEVEHGAAPGAGGGGG
PGRWHL*QGQCAHPALRRQEGLCLRAGSE*GVP
RPPTPLPGAAGPAEGPGRGGADHASHQHAARHLP
EPEHDCGSRLVPGPAEADAGEGGRDPLGQQVPS
QAPASWETRQVRPPH*LHGGFHHPQPPEQDFLG
QQVTFGQNRTPGGEPARLAMPG*GQEEQSPILVP
DPGLLHPCLLLPGTQPAAWGPGPQSCQLSPAGF
LSSQHLPSTGLPLGRGRTGRRRGPGGNLFLEPA
LAPHRQVLPTGSPCALHGVYPGAGGGGGEQRREP
DSC*PLGHGASNHLPRAPGWQHPPLQQCGHWHP
VPGELQEPRSAACALPATQPLPPARWPAGWDPC
CLPSDQRRCPVGPGEPSRVPDCGARACPHPVEPG
GCRVGQLWALGHCPGSHHPAASAKLRGAPGRGS
ERDTHGEGGQRRLDGLLLRHLHPPLPH*DPGAS
ARDQHRHQDHLPPARPEALVCHQPPDLPGSALGG
H*PGCHRPAARASAGRHPQDHRERHGLTQRALW
ACGLPGCGYQHPGP*HPAE*PGGG*GAPG*GGQ
ARRAGTRAHAR*PRGPRADPQEGHPLAVPPALHR
TPPGPAALHAGAGAC*WRSFGAQRGGRLHLRDG
RRPRHLGAQPALRPRRPPQGDLLCGHHLRRAGL
PQLWQRSGQQWEAGPVWGDGQHPPHLAGALDAIA
PPLSPQRAQLQA*PRPRPALVL*DLHGTCGWAW
TLQKLLGQSKGKPLVLKKFFSECFGEEF*GLGR
GRTHLEEMAFFLKAKNTKPHNCLASPVSLVWALA
GLQGSHTPLLEGCVRVSVCECVGWCVNIYK*VY
MVYIICV*IKSVHIGALGDAGIKDKSYIWTW

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