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Sequences

Sequence NM_173059

GCCATGTTGATTTCTGATCCTTGAGCTTTTCTGTGTTTCTCTGTTCATTCTTCATGGCATCCTTGGAAGGATGCCAAGCTAAGGAGGCCAGGGGGGAATA AAAGGAGTCCAGGCTCCCAACTGTGCCCTTCCCCTCTCCCCTGGGAGCAACCACTTAGGGTCCTCATGGTTCCTCCAGTCTGGACTCTGCTGCTTCTGGT GGGGGCTGCCCTTTTCAGGAAAGAGAAGCCTCCGGACCAGAAGCTGGTTGTTCGCAGCTCTAGGGACAACTATGTCCTCACCCAGTGTGATTTTGAGGAT GACGCCAAACCCCTCTGTGACTGGTCCCAAGTGTCCGCAGACGATGAAGACTGGGTTCGAGCCAGTGGGCCCTCTCCCACCGGCTCCACCGGGGCCCCCG GGGGGTACCCTAACGGAGAGGGCAGCTATCTGCATATGGAATCGAACAGCTTCCACCGTGGGGGAGTGGCCCGCCTGCTCAGCCCCGACCTATGGGAGCA AGGCCCCCTCTGTGTGCACTTTGCCCACCACATGTTCGGGCTGTCTTGGGGCGCCCAGCTCAGGCTGCTGCTGCTCTCGGGTGAAGAGGGCCGCCGCCCC GATGTGCTCTGGAAACACTGGAACACCCAGAGACCCTCCTGGATGCTCACCACCGTCACTGTGCCCGCAGGGTTCACCCTGCCCACCCGGCTGATGTTTG AGGGAACACGGGGTAGCACTGCCTACCTGGACATCGCCCTGGATGCCCTCTCTATCCGCCGGGGCTCCTGTAATCGCGTCTGTATGATGCAAACATGCAG CTTTGACATTCCAAATGACCTCTGTGACTGGACCTGGATCCCAACTGCCTCCGGGGCCAAGTGGACTCAGAAGAAAGGGTCATCAGGAAAGCCAGGCGTG GGGCCTGATGGCGACTTCTCTAGCCCTGGTAGTGGCTGCTACATGCTCCTGGACCCCAAGAATGCAAGACCTGGGCAGAAAGCTGTCCTCCTGAGCCCCG TGAGCCTGTCCTCTGGCTGTCTGAGCTTTTCCTTCCACTACATCCTCCGGGGCCAGTCTCCTGGTGCAGCCCTCCACATTTATGCTTCAGTCTTGGGGAG TATCCGGAAACACACTCTCTTCTCAGGACAACCTGGGCCCAACTGGCAGGCTGTTTCTGTCAATTACACAGCCGTGGGACGGATACAGTTTGCCGTGGTA GGCGTTTTTGGAAAGACCCCAGAGCCAGCTGTGGCAGTTGATGCAACCAGCATTGCTCCTTGTGGGGAGGGTTTTCCTCAGTGTGACTTTGAAGACAACG CCCATCCCTTCTGTGACTGGGTCCAGACTTCCGGGGATGGTGGACACTGGGCCCTCGGACATAAAAATGGACCCGTCCATGGCATGGGCCCTGCGGGAGG TTTCCCTAATGCAGGGGGTCACTATATCTACCTTGAGGCTGACGAGTTCTCCCAGGCAGGCCAGTCAGTCAGACTGGTGAGCCGGCCCTTCTGCGCCCCA GGTGACATCTGCGTGGAGTTCGCATACCACATGTATGGCCTTGGGGAGGGTACTATGCTCGAACTCCTCCTGGGAAGTCCTGCGGGGAGTCCCCCGATTC CTCTCTGGAAACGCGTGGGGTCTCAGCGCCCTTACTGGCAGAACACCTCCGTCACCGTCCCCTCAGGACACCAACAGCCCATGCAGCTTATTTTCAAGGG CATCCAGGGAAGCAACACGGCCTCTGTGGTTGCTATGGGTTTCATCTTGATCAATCCTGGGACTTGTCCAGTAAAAGTGCTACCAGAGCTTCCTCCCGTA TCTCCAGTTTCTTCCACTGGCCCTTCTGAAACCACTGGCCTCACAGAAAACCCTACAATCTCCACCAAGAAACCTACAGTTTCCATAGAAAAACCCAGTG TCACCACAGAAAAGCCCACAGTCCCCAAAGAAAAGCCCACCATTCCCACAGAAAAACCCACCATCTCCACAGAAAAACCCACCATTCCTTCAGAAAAACC CAACATGCCCTCAGAAAAACCCACCATTCCCTCAGAAAAACCCACCATCCTCACAGAAAAACCCACCATTCCCTCAGAAAAACCCACCATTCCCTCAGAA AAACCCACCATTTCCACAGAAAAACCCACCGTCCCCACAGAAGAGCCCACCACCCCCACTGAGGAGACCACCACCTCCATGGAAGAGCCTGTCATCCCTA CAGAAAAACCCAGCATCCCTACAGAAAAACCCAGCATCCCCACGGAAAAACCCACCATCTCCATGGAAGAGACTATCATCTCCACAGAAAAACCCACCAT CTCCCCAGAAAAACCCACCATCCCCACAGAAAAACCCACCATCCCCACAGAAAAATCCACCATCTCCCCAGAAAAACCCACCACCCCCACAGAAAAACCC ACCATCCCCACAGAAAAACCCACCATCTCCCCAGAAAAACCCACCACCCCCACAGAAAAACCCACCATCTCCCCAGAAAAACTCACCATCCCCACAGAAA AACCCACCATCCCCACAGAAAAACCCACCATTCCCACAGAAAAACCCACCATCTCCACAGAAGAGCCCACCACCCCCACTGAGGAGACCACCATCTCCAC AGAAAAACCCAGCATCCCCATGGAAAAACCCACTCTCCCCACTGAAGAAACCACCACCTCTGTTGAAGAGACTACCATCTCTACAGAAAAACTCACCATC CCCATGGAAAAACCCACCATCTCCACAGAAAAACCCACCATCCCCACAGAAAAACCCACCATCTCCCCAGAAAAACTCACCATCCCCACGGAAAAACTCA CCATCCCCACGGAAAAACCCACCATCCCCATTGAAGAGACTACCATCTCCACAGAAAAACTCACCATCCCCACAGAAAAACCCACCATCTCCCCAGAAAA ACCCACCATCTCCACGGAAAAACCCACCATCCCCACGGAAAAACCCACCATCCCCACTGAAGAGACTACCATCTCCACAGAAAAACTCACCATCCCCACA GAAAAACCCACCATCTCCCCAGAAAAACTCACCATCCCCACAGAAAAACCCACCATCTCCACGGAAAAACCCACCATCCCCACGGAAAAACTTACCATCC CCACGGAAAAACCCACCATCCCCACAGAAAAACCCACCATTCCCACAGAGAAGCTCACAGCCCTGAGGCCACCCCATCCCAGCCCCACAGCCACTGGGCT GGCAGCCTTGGTGATGTCTCCACATGCTCCAAGTACCCCTATGACCAGTGTGATTCTGGGCACTACCACAACCTCCAGATCCAGTACAGAGCGCTGCCCT CCAAATGCCCGCTACGAATCCTGTGCTTGTCCTGCTTCGTGCAAGAGCCCCAGGCCTAGCTGTGGGCCCCTCTGTCGGGAGGGCTGTGTCTGCAACCCTG GCTTTTTGTTTAGTGACAACCACTGCATCCAGGCCTCTTCCTGCAATTGCTTCTACAACAACGACTACTATGAGCCTGGGGCAGAGTGGTTCAGCCCCAA CTGCACAGAACATTGCCGCTGCTGGCCCGGCAGTCGGGTCGAGTGCCAGATCTCTCAGTGTGGGACACACACCGTGTGCCAGCTTAAGAATGGCCAGTAT GGATGCCACCCCTACGCAGGCACTGCCACCTGCTTGGTCTACGGAGACCCTCATTATGTCACCTTTGACGGGAGGCACTTTGGCTTCATGGGCAAGTGCA CTTACATCTTGGCCCAGCCCTGTGGCAACTCAACAGACCCATTCTTCAGGGTGACAGCCAAGAATGAGGAGCAGGGACAGGAAGGCGTGTCCTGCCTGAG CAAAGTCTACGTGACCCTGCCCGAGAGCACCGTCACCCTGCTTAAGGGCAGACGCACTCTGGTTGGGGGTCAGCAAGTTACTCTCCCAGCCATACCCTCT AAAGGCGTCTTCCTGGGTGCAAGCGGGCGGTTTGTGGAGCTGCAGACGGAGTTCGGTTTGCGGGTGAGATGGGATGGTGACCAGCAGCTGTATGTTACTG TGTCCAGCACATACTCTGGCAAACTCTGTGGTTTGTGTGGGAACTATGACGGCAACAGTGACAATGACCACCTGAAGTTGGACGGCAGCCCAGCAGGAGA CAAGGAGGAGCTGGGGAACAGCTGGCAGACGGACCAGGACGAGGACCAGGAGTGTCAGAAGTACCAGGTGGTGAATTCCCCGTCTTGTGATTCATCTCTG CAGAGCAGCATGTCGGGGCCAGGGTTCTGTGGACGGCTGGTCGACACTCATGGCCCATTTGAGACATGCCTGCTGCACGTGAAGGCCGCTTCCTTCTTCG ACAGCTGCATGCTTGATATGTGCGGATTCCAGGGGCTGCAGCACCTGCTGTGCACACACATGTCCACCATGACCACCACCTGCCAGGACGCAGGCCACGC TGTGAAGCCCTGGAGGGAACCCCACTTCTGCCCAATGGCCTGCCCGCCCAACAGCAAGTACTCCCTGTGTGCGAAGCCATGCCCTGACACCTGCCATTCA GGATTCTCCGGCATGTTCTGCTCAGACCGGTGCGTGGAGGCCTGTGAATGCAATCCGGGCTTCGTCCTCAGTGGCCTCGAGTGCATACCTCGCTCCCAGT GTGGGTGCCTCCACCCTGCAGGCAGCTACTTCAAGGTAGGGGAGCGGTGGTACAAGCCAGGCTGCAAAGAGTTGTGCGTCTGTGAAAGCAACAACAGAAT TCGCTGCCAGCCCTGGAGGTGTAGGGCCCAGGAGTTCTGTGGCCAACAGGATGGTATCTATGGCTGCCATGCCCAAGGTGCCGCCACCTGCACAGCCTCG GGTGACCCCCACTACCTGACCTTCGATGGCGCCTTGCACCACTTCATGGGCACCTGCACCTATGTCCTGACCCGGCCTTGCTGGTCCAGGTCCCAAGACA GCTATTTTGTTGTGAGCGCCACCAACGAGAACCGCGGGGGGATCCTGGAGGTCTCCTACATCAAAGCCGTCCACGTGACAGTCTTTGACCTCAGCATCTC ACTGCTCAGAGGCTGTAAGGTCATGCTGAATGGCCATCGGGTGGCCCTACCTGTGTGGCTTGCACAAGGCCGGGTGACCATAAGGCTCAGCAGCAACCTC GTCCTCCTCTACACGAACTTTGGGCTCCAAGTTCGCTACGACGGGAGCCACTTGGTGGAAGTGACAGTCCCCTCCTCCTATGGCGGCCAGCTCTGTGGGC TGTGTGGGAACTACAACAACAACAGCTTGGATGACAACCTGCGCCCCGACAGAAAGCTTGCAGGCGATTCCATGCAGCTGGGGGCCGCCTGGAAGTTACC TGAATCCTCTGAACCTGGCTGTTTCCTTGTGGGTGGCAAGCCCTCCAGCTGCCAGGAGAACAGCATGGCAGACGCCTGGAACAAGAACTGTGCGATCTTA ATAAACCCTCAGGGACCCTTCTCTCAATGTCACCAGGTGGTGCCTCCCCAGTCCAGCTTTGCCAGTTGCGTGCATGGTCAGTGTGGGACCAAGGGCGACA CCACAGCCCTGTGCCGCTCCCTGCAGGCCTACGCGTCCCTGTGTGCCCAGGCTGGCCAGGCCCCTGCCTGGCGGAACAGAACCTTCTGCCCTATGAGGTG CCCACCTGGCAGCAGCTACAGCCCCTGCAGCAGCCCCTGCCCAGACACCTGCAGCAGCATAAACAACCCGAGGGACTGCCCCAAAGCACTGCCCTGTGCT GAGAGCTGTGAATGTCAGAAAGGCCACATCTTGAGTGGAACCTCCTGCGTGCCCCTTGGCCAGTGTGGCTGCACTGACCCAGCGGGCTCCTACCACCCGG TCGGGGAGCGCTGGTACACAGAGAACACCTGCACCAGGCTCTGCACCTGCTCCGTCCACAACAACATCACCTGCTTCCAGAGCACCTGCAAACCCAACCA GATATGCTGGGCCCTGGATGGGCTGCTCCGTTTCGGGCCTCAGGTGTGGGAGTGTGTCAGCTCCCAGGGGAGTCCCACTACGTGAGCTTTGATGGTAGTA ACCATTCTATCCCGGACGCCTGCACTCTTGTCCTGGTGAAAGTGTGCCACCCCGCCATGGCCTTGCCCTTCTTCAAGATCAGTGCCAAGCATGAGAAGGA GGAAGGTGGAACTGAGGCTTTCCGCCTTCATGAGGTCTACATTGACATCTACGATGCCCAGGTCACCCTGCAGAAGGGCCACCGTGTGCTAATCAACAGC AAACAGGTCACCCTCCCCGCCATCTCCCAGATCCCTGGGGTCAGTGTCAAGTCCAGCAGCATCTACAGCATTGTTAACATCAAGATCGGGGTGCAAGTCA AGTTTGACGGGAATCATCTCTTAGAGATTGAAATCCCCACAACCTACTATGGAAAGGTCTGCGGCATGTGTGGGAACTTCAATGATGAGGAAGAGGACGA ACTAATGATGCCCAGCGATGAAGTAGCAAATAGTGACAGTGAATTTGTGAACAGTTGGAAAGATAAGGACATTGACCCAAGTTGTCAGAGTCTCCTGGTA GATGAGCAGCAGATTCCAGCGGAACAGCAGGAGAACCCGAGTGGAAACTGCAGGGCGGCCGACCTCCGCAGGGCGCGGGAAAAGTGCGAGGCAGCGCTCC GGGCTCCTGTGTGGGCCCAGTGCGCCTCCCGCATAGACCTCACGCCCTTCCTGGTGGACTGTGCAAACACCCTCTGTGAGTTCGGAGGTCTCTACCAGGC CCTCTGCCAGGCTCTGCAAGCCTTCGGGGCCACCTGCCAGAGCCAGGGGCTCAAGCCCCCACTCTGGAGAAACAGCAGCTTCTGCCCTCTGGAATGCCCT GCCTACAGCAGCTACACCAACTGCCTTCCCTCCTGCTCACCCTCCTGCTGGGACCTGGATGGCCGGTGTGAGGGCGCCAAAGTCCCCTCTGCCTGCGCTG AGGGCTGCATTTGTCAGCCCGGCTATGTGCTGAGTGAAGACAAGTGTGTCCCCAGAAGTCAGTGTGGCTGCAAGGATGCCCATGGTGGCTCCATCCCTCT GGGCAAGAGCTGGGTCTCCAGCGGTTGCACGGAGAAGTGTGTCTGCACGGGAGGAGCCATTCAGTGCGGGGACTTCCGATGCCCCTCTGGGTCCCACTGC CAGCTCACTTCCGACAACAGCAACAGCAATTGTGTCTCAGACAAGTCTGAACAATGCTCAGTCTATGGCGACCCCCGTTACCTCACATTTGACGGCTTCA GCTACCGCTTGCAAGGCCGCATGACCTATGTTCTGATCAAGACTGTGGACGTACTGCCTGAGGGGGTGGAGCCCCTCCTCGTGGAAGGACGCAACAAGAT GGATCCGCCCAGGAGCTCCATCTTCTTGCAGGAAGTGATTACCACCGTCTACGGCTATAAAGTGCAGCTCCAAGCTGGTCTGGAGCTTGTGGTCAACAAC CAGAAGATGGCCGTCCCCTACAGGCCAAATGAACACCTGCGGGTCACCCTGTGGGGCCAACGGCTCTACCTGGTCACCGACTTTGAGCTGGTCGTCAGCT TTGGTGGAAGGAAAAATGCAGTGATCTCCCTACCCAGCATGTACGAGGGGCTTGTGAGTGGCCTGTGCGGAAACTACGACAAGAACCGCAAGAATGACAT GATGCTGCCCAGTGGCGCCCTGACCCAGAACCTCAACACCTTTGGCAACAGCTGGGAGGTGAAGACCGAGGACGCACTCCTGCGCTTCCCCAGGGCTATA CCAGCGGAGGAGGAGGGACAAGGGGCGGAGCTGGGCCTCCGCACGGGCCTCCAAGTGTCCGAATGTAGCCCGGAGCAGCTGGCGAGCAACAGCACCCAGG CCTGTAGGGTGCTGGCAGACCCCCAGGGCCCCTTTGCTGCCTGTCACCAGACGGTGGCCCCAGAGCCCTTCCAAGAGCACTGCGTGCTGGATCTGTGCTC TGCTCAGGACCCAAGAGAGCAAGAGGAGCTGCGTTGCCAGGTCCTCAGTGGGTACGCCATCCTCTGCCAGGAGGCGGGCGCTGCCCTGGCTGGCTGGCGG GACCGCACCCTCTGCGAAAGCCCGTGTCTGCAGAACCCCTGTCAGAATGACGGGCAGTGTCGGGAGCAGGGAGCCACCTTCACCTGCGAGTGTGAAGTTG GTTACGGGGGAGGCCTGTGTATGGAGCCTCGAGATGCGCCACCTCCCAGAAAGCCAGCATCTAACCTGGTGGGCGTCCTACTGGGACTGCTGGTGCCTGT GGTGGTCGTACTACTGGCCGTGACCAGAGAGTGCATTTACAGAACGAGGAGGAAGAGAGAGAAAACGCAGGAGGGAGACAGACTGGCCAGGCTGGTGGAC ACAGATACTGTTCTGGACTGTGCCTGTTAAGTTGCTCAGTTTTGAGCTGTCTTCAGACAAGAAGATTAAATAAATTTATATATTTATTTATTTGA

refseq_ZAN.F1 (forward primer)
refseq_ZAN.R1 (reverse primer)
Exon skipping and alternative donor or acceptor

Frame 0

AMLISDP*AFLCFSVHSSWHPWKDAKLRRPGGN KRSPGSQLCPSPLPWEQPLRVLMVPPVWTLLLLV GAALFRKEKPPDQKLVVRSSRDNYVLTQCDFED DAKPLCDWSQVSADDEDWVRASGPSPTGSTGAP GGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQ GPLCVHFAHHMFGLSWGAQLRLLLLSGEEGRRP DVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMF EGTRGSTAYLDIALDALSIRRGSCNRVCMMQTCS FDIPNDLCDWTWIPTASGAKWTQKKGSSGKPGV GPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSP VSLSSGCLSFSFHYILRGQSPGAALHIYASVLGS IRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVV GVFGKTPEPAVAVDATSIAPCGEGFPQCDFEDN AHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGG FPNAGGHYIYLEADEFSQAGQSVRLVSRPFCAP GDICVEFAYHMYGLGEGTMLELLLGSPAGSPPI PLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKG IQGSNTASVVAMGFILINPGTCPVKVLPELPPV SPVSSTGPSETTGLTENPTISTKKPTVSIEKPS VTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKP NMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIP TEKPSIPTEKPSIPTEKPTISMEETIISTEKPTI SPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP TIPTEKPTISPEKPTTPTEKPTISPEKLTIPTE KPTIPTEKPTIPTEKPTISTEEPTTPTEETTIST EKPSIPMEKPTLPTEETTTSVEETTISTEKLTI PMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEK PTISTEKPTIPTEKPTIPTEETTISTEKLTIPT EKPTISPEKLTIPTEKPTISTEKPTIPTEKLTI PTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGL AALVMSPHAPSTPMTSVILGTTTTSRSSTERCP PNARYESCACPASCKSPRPSCGPLCREGCVCNP GFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPN CTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKC TYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLS KVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS KGVFLGASGRFVELQTEFGLRVRWDGDQQLYVT VSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGD KEELGNSWQTDQDEDQECQKYQVVNSPSCDSSL QSSMSGPGFCGRLVDTHGPFETCLLHVKAASFF DSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHA VKPWREPHFCPMACPPNSKYSLCAKPCPDTCHS GFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ CGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTAS GDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQD SYFVVSATNENRGGILEVSYIKAVHVTVFDLSIS LLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNL VLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCG LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLP ESSEPGCFLVGGKPSSCQENSMADAWNKNCAIL INPQGPFSQCHQVVPPQSSFASCVHGQCGTKGD TTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC PPGSSYSPCSSPCPDTCSSINNPRDCPKALPCA ESCECQKGHILSGTSCVPLGQCGCTDPAGSYHP VGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQ ICWALDGLLRFGPQVWECVSSQGSPTT*ALMVV TILSRTPALLSW*KCATPPWPCPSSRSVPSMRR RKVELRLSAFMRSTLTSTMPRSPCRRATVC*STA NRSPSPPSPRSLGSVSSPAASTALLTSRSGCKS SLTGIIS*RLKSPQPTMERSAACVGTSMMRKRT N**CPAMK*QIVTVNL*TVGKIRTLTQVVRVSW* MSSRFQRNSRRTRVETAGRPTSAGRGKSARQRS GLLCGPSAPPA*TSRPSWWTVQTPSVSSEVSTR PSARLCKPSGPPARARGSSPHSGETAASALWNAL PTAATPTAFPPAHPPAGTWMAGVRAPKSPLPAL RAAFVSPAMC*VKTSVSPEVSVAARMPMVAPSL WARAGSPAVARRSVSAREEPFSAGTSDAPLGPTA SSLPTTATAIVSQTSLNNAQSMATPVTSHLTAS ATACKAA*PMF*SRLWTYCLRGWSPSSWKDATR WIRPGAPSSCRK*LPPSTAIKCSSKLVWSLWSTT RRWPSPTGQMNTCGSPCGANGSTWSPTLSWSSA LVEGKMQ*SPYPACTRGL*VACAETTTRTARMT *CCPVAP*PRTSTPLATAGR*RPRTHSCASPGLY QRRRRDKGRSWASARASKCPNVARSSWRATAPR PVGCWQTPRAPLLPVTRRWPQSPSKSTACWICA LLRTQESKRSCVARSSVGTPSSARRRALPWLAGG TAPSAKARVCRTPVRMTGSVGSREPPSPASVKL VTGEACVWSLEMRHLPESQHLTWWASYWDCWCL WWSYYWP*PESAFTERGGRERKRRRETDWPGWWT QILFWTVPVKLLSFELSSDKKIK*IYIFIYL

Frame 1

PC*FLILELFCVSLFILHGILGRMPS*GGQGGI KGVQAPNCALPLSPGSNHLGSSWFLQSGLCCFW WGLPFSGKRSLRTRSWLFAALGTTMSSPSVILRM TPNPSVTGPKCPQTMKTGFEPVGPLPPAPPGPP GGTLTERAAICIWNRTASTVGEWPACSAPTYGS KAPSVCTLPTTCSGCLGAPSSGCCCSRVKRAAAP MCSGNTGTPRDPPGCSPPSLCPQGSPCPPG*CL REHGVALPTWTSPWMPSLSAGAPVIASV*CKHA ALTFQMTSVTGPGSQLPPGPSGLRRKGHQESQAW GLMATSLALVVAATCSWTPRMQDLGRKLSS*AP *ACPLAV*AFPSTTSSGASLLVQPSTFMLQSWG VSGNTLSSQDNLGPTGRLFLSITQPWDGYSLPW* AFLERPQSQLWQLMQPALLLVGRVFLSVTLKTT PIPSVTGSRLPGMVDTGPSDIKMDPSMAWALRE VSLMQGVTISTLRLTSSPRQASQSDW*AGPSAPQ VTSAWSSHTTCMALGRVLCSNSSWEVLRGVPRF LSGNAWGLSALTGRTPPSPSPQDTNSPCSLFSR ASREATRPLWLLWVSS*SILGLVQ*KCYQSFLPY LQFLPLALLKPLASQKTLQSPPRNLQFP*KNPV SPQKSPQSPKKSPPFPQKNPPSPQKNPPFLQKN PTCPQKNPPFPQKNPPSSQKNPPFPQKNPPFPQK NPPFPQKNPPSPQKSPPPPLRRPPPPWKSLSSL QKNPASLQKNPASPRKNPPSPWKRLSSPQKNPP SPQKNPPSPQKNPPSPQKNPPSPQKNPPPPQKNP PSPQKNPPSPQKNPPPPQKNPPSPQKNSPSPQK NPPSPQKNPPFPQKNPPSPQKSPPPPLRRPPSP QKNPASPWKNPLSPLKKPPPLLKRLPSLQKNSPS PWKNPPSPQKNPPSPQKNPPSPQKNSPSPRKNS PSPRKNPPSPLKRLPSPQKNSPSPQKNPPSPQK NPPSPRKNPPSPRKNPPSPLKRLPSPQKNSPSPQ KNPPSPQKNSPSPQKNPPSPRKNPPSPRKNLPS PRKNPPSPQKNPPFPQRSSQP*GHPIPAPQPLG WQPW*CLHMLQVPL*PV*FWALPQPPDPVQSAAL QMPATNPVLVLLRARAPGLAVGPSVGRAVSATL AFCLVTTTASRPLPAIASTTTTTMSLGQSGSAP TAQNIAAAGPAVGSSARSLSVGHTPCASLRMASM DATPTQALPPAWSTETLIMSPLTGGTLASWASA LTSWPSPVATQQTHSSG*QPRMRSRDRKACPA* AKST*PCPRAPSPCLRADALWLGVSKLLSQPYPL KASSWVQAGGLWSCRRSSVCG*DGMVTSSCMLL CPAHTLANSVVCVGTMTATVTMTT*SWTAAQQE TRRSWGTAGRRTRTRTRSVRSTRW*IPRLVIHLC RAACRGQGSVDGWSTLMAHLRHACCT*RPLPSS TAACLICADSRGCSTCCAHTCPP*PPPARTQAT L*SPGGNPTSAQWPARPTASTPCVRSHALTPAIQ DSPACSAQTGAWRPVNAIRASSSVASSAYLAPS VGASTLQAATSR*GSGGTSQAAKSCASVKATTE FAASPGGVGPRSSVANRMVSMAAMPKVPPPAQPR VTPTT*PSMAPCTTSWAPAPMS*PGLAGPGPKT AILL*APPTRTAGGSWRSPTSKPST*QSLTSAS HCSEAVRSC*MAIGWPYLCGLHKAG*P*GSAATS SSSTRTLGSKFATTGATWWK*QSPPPMAASSVG CVGTTTTTAWMTTCAPTESLQAIPCSWGPPGSY LNPLNLAVSLWVASPPAARRTAWQTPGTRTVRS* *TLRDPSLNVTRWCLPSPALPVACMVSVGPRAT PQPCAAPCRPTRPCVPRLARPLPGGTEPSAL*G AHLAAATAPAAAPAQTPAAA*TTRGTAPKHCPVL RAVNVRKATS*VEPPACPLASVAALTQRAPTTR SGSAGTQRTPAPGSAPAPSTTTSPASRAPANPT RYAGPWMGCSVSGLRCGSVSAPRGVPLREL*W** PFYPGRLHSCPGESVPPRHGLALLQDQCQA*EG GRWN*GFPPS*GLH*HLRCPGHPAEGPPCANQQ QTGHPPRHLPDPWGQCQVQQHLQHC*HQDRGASQ V*RESSLRD*NPHNLLWKGLRHVWELQ**GRGR TNDAQR*SSK**Q*ICEQLER*GH*PKLSESPG R*AADSSGTAGEPEWKLQGGRPPQGAGKVRGSAP GSCVGPVRLPHRPHALPGGLCKHPL*VRRSLPG PLPGSASLRGHLPEPGAQAPTLEKQQLLPSGMP CLQQLHQLPSLLLTLLLGPGWPV*GRQSPLCLR* GLHLSARLCAE*RQVCPQKSVWLQGCPWWLHPS GQELGLQRLHGEVCLHGRSHSVRGLPMPLWVPL PAHFRQQQQQLCLRQV*TMLSLWRPPLPHI*RLQ LPLARPHDLCSDQDCGRTA*GGGAPPRGRTQQD GSAQELHLLAGSDYHRLRL*SAAPSWSGACGQQ PEDGRPLQAK*TPAGHPVGPTALPGHRL*AGRQL WWKEKCSDLPTQHVRGACEWPVRKLRQEPQE*H DAAQWRPDPEPQHLWQQLGGEDRGRTPALPQGY TSGGGGTRGGAGPPHGPPSVRM*PGAAGEQQHPG L*GAGRPPGPLCCLSPDGGPRALPRALRAGSVL CSGPKRARGAALPGPQWVRHPLPGGGRCPGWLA GPHPLRKPVSAEPLSE*RAVSGAGSHLHLRV*SW LRGRPVYGASRCATSQKASI*PGGRPTGTAGAC GGRTTGRDQRVHLQNEEEERENAGGRQTGQAGG HRYCSGLCLLSCSVLSCLQTRRLNKFIYLFI*

Frame 2

HVDF*SLSFSVFLCSFFMASLEGCQAKEARGE* KESRLPTVPFPSPLGATT*GPHGSSSLDSAASG GGCPFQEREASGPEAGCSQL*GQLCPHPV*F*G *RQTPL*LVPSVRRR*RLGSSQWALSHRLHRGPR GVP*RRGQLSAYGIEQLPPWGSGPPAQPRPMGA RPPLCALCPPHVRAVLGRPAQAAAALG*RGPPP RCALETLEHPETLLDAHHRHCARRVHPAHPADV* GNTG*HCLPGHRPGCPLYPPGLL*SRLYDANMQ L*HSK*PL*LDLDPNCLRGQVDSEERVIRKARR GA*WRLL*PW*WLLHAPGPQECKTWAESCPPEPR EPVLWLSELFLPLHPPGPVSWCSPPHLCFSLGE YPETHSLLRTTWAQLAGCFCQLHSRGTDTVCRG RRFWKDPRASCGS*CNQHCSLWGGFSSV*L*RQR PSLL*LGPDFRGWWTLGPRT*KWTRPWHGPCGR FP*CRGSLYLP*G*RVLPGRPVSQTGEPALLRP R*HLRGVRIPHVWPWGGYYARTPPGKSCGESPDS SLETRGVSAPLLAEHLRHRPLRTPTAHAAYFQG HPGKQHGLCGCYGFHLDQSWDLSSKSATRASSR ISSFFHWPF*NHWPHRKPYNLHQETYSFHRKTQC HHRKAHSPQRKAHHSHRKTHHLHRKTHHSFRKT QHALRKTHHSLRKTHHPHRKTHHSLRKTHHSLR KTHHFHRKTHRPHRRAHHPH*GDHHLHGRACHPY RKTQHPYRKTQHPHGKTHHLHGRDYHLHRKTHH LPRKTHHPHRKTHHPHRKIHHLPRKTHHPHRKT HHPHRKTHHLPRKTHHPHRKTHHLPRKTHHPHRK THHPHRKTHHSHRKTHHLHRRAHHPH*GDHHLH RKTQHPHGKTHSPH*RNHHLC*RDYHLYRKTHH PHGKTHHLHRKTHHPHRKTHHLPRKTHHPHGKTH HPHGKTHHPH*RDYHLHRKTHHPHRKTHHLPRK THHLHGKTHHPHGKTHHPH*RDYHLHRKTHHPH RKTHHLPRKTHHPHRKTHHLHGKTHHPHGKTYHP HGKTHHPHRKTHHSHREAHSPEATPSQPHSHWA GSLGDVSTCSKYPYDQCDSGHYHNLQIQYRALP SKCPLRILCLSCFVQEPQA*LWAPLSGGLCLQPW LFV**QPLHPGLFLQLLLQQRLL*AWGRVVQPQ LHRTLPLLARQSGRVPDLSVWDTHRVPA*EWPV WMPPLRRHCHLLGLRRPSLCHL*REALWLHGQVH LHLGPALWQLNRPILQGDSQE*GAGTGRRVLPE QSLRDPAREHRHPA*GQTHSGWGSASYSPSHTL *RRLPGCKRAVCGAADGVRFAGEMGW*PAAVCYC VQHILWQTLWFVWEL*RQQ*Q*PPEVGRQPSRR QGGAGEQLADGPGRGPGVSEVPGGEFPVL*FIS AEQHVGARVLWTAGRHSWPI*DMPAAREGRFLLR QLHA*YVRIPGAAAPAVHTHVHHDHHLPGRRPR CEALEGTPLLPNGLPAQQQVLPVCEAMP*HLPF RILRHVLLRPVRGGL*MQSGLRPQWPRVHTSLPV WVPPPCRQLLQGRGAVVQARLQRVVRL*KQQQN SLPALEV*GPGVLWPTGWYLWLPCPRCRHLHSL G*PPLPDLRWRLAPLHGHLHLCPDPALLVQVPRQ LFCCERHQREPRGDPGGLLHQSRPRDSL*PQHL TAQRL*GHAEWPSGGPTCVACTRPGDHKAQQQP RPPLHELWAPSSLRREPLGGSDSPLLLWRPALWA VWELQQQQLG*QPAPRQKACRRFHAAGGRLEVT *IL*TWLFPCGWQALQLPGEQHGRRLEQELCDL NKPSGTLLSMSPGGASPVQLCQLRAWSVWDQGRH HSPVPLPAGLRVPVCPGWPGPCLAEQNLLPYEV PTWQQLQPLQQPLPRHLQQHKQPEGLPQSTALC *EL*MSERPHLEWNLLRAPWPVWLH*PSGLLPPG RGALVHREHLHQALHLLRPQQHHLLPEHLQTQP DMLGPGWAAPFRASGVGVCQLPGESHYVSFDGS NHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE EGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINS KQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQV KFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLV DEQQIPAEQQENPSGNCRAADLRRAREKCEAAL RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQA LCQALQAFGATCQSQGLKPPLWRNSSFCPLECP AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACA EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL GKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHC QLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGF SYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKM DPPRSSIFLQEVITTVYGYKVQLQAGLELVVNN QKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVS FGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDM MLPSGALTQNLNTFGNSWEVKTEDALLRFPRAI PAEEEGQGAELGLRTGLQVSECSPEQLASNSTQ ACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCS AQDPREQEELRCQVLSGYAILCQEAGAALAGWR DRTLCESPCLQNPCQNDGQCREQGATFTCECEV GYGGGLCMEPRDAPPPRKPASNLVGVLLGLLVPV VVVLLAVTRECIYRTRRKREKTQEGDRLARLVD TDTVLDCAC*VAQF*AVFRQED*INLYIYLF

Sequence NM_003386

GCCATGTTGATTTCTGATCCTTGAGCTTTTCTGTGTTTCTCTGTTCATTCTTCATGGCATCCTTGGAAGGATGCCAAGCTAAGGAGGCCAGGGGGGAATA AAAGGAGTCCAGGCTCCCAACTGTGCCCTTCCCCTCTCCCCTGGGAGCAACCACTTAGGGTCCTCATGGTTCCTCCAGTCTGGACTCTGCTGCTTCTGGT GGGGGCTGCCCTTTTCAGGAAAGAGAAGCCTCCGGACCAGAAGCTGGTTGTTCGCAGCTCTAGGGACAACTATGTCCTCACCCAGTGTGATTTTGAGGAT GACGCCAAACCCCTCTGTGACTGGTCCCAAGTGTCCGCAGACGATGAAGACTGGGTTCGAGCCAGTGGGCCCTCTCCCACCGGCTCCACCGGGGCCCCCG GGGGGTACCCTAACGGAGAGGGCAGCTATCTGCATATGGAATCGAACAGCTTCCACCGTGGGGGAGTGGCCCGCCTGCTCAGCCCCGACCTATGGGAGCA AGGCCCCCTCTGTGTGCACTTTGCCCACCACATGTTCGGGCTGTCTTGGGGCGCCCAGCTCAGGCTGCTGCTGCTCTCGGGTGAAGAGGGCCGCCGCCCC GATGTGCTCTGGAAACACTGGAACACCCAGAGACCCTCCTGGATGCTCACCACCGTCACTGTGCCCGCAGGGTTCACCCTGCCCACCCGGCTGATGTTTG AGGGAACACGGGGTAGCACTGCCTACCTGGACATCGCCCTGGATGCCCTCTCTATCCGCCGGGGCTCCTGTAATCGCGTCTGTATGATGCAAACATGCAG CTTTGACATTCCAAATGACCTCTGTGACTGGACCTGGATCCCAACTGCCTCCGGGGCCAAGTGGACTCAGAAGAAAGGGTCATCAGGAAAGCCAGGCGTG GGGCCTGATGGCGACTTCTCTAGCCCTGGTAGTGGCTGCTACATGCTCCTGGACCCCAAGAATGCAAGACCTGGGCAGAAAGCTGTCCTCCTGAGCCCCG TGAGCCTGTCCTCTGGCTGTCTGAGCTTTTCCTTCCACTACATCCTCCGGGGCCAGTCTCCTGGTGCAGCCCTCCACATTTATGCTTCAGTCTTGGGGAG TATCCGGAAACACACTCTCTTCTCAGGACAACCTGGGCCCAACTGGCAGGCTGTTTCTGTCAATTACACAGCCGTGGGACGGATACAGTTTGCCGTGGTA GGCGTTTTTGGAAAGACCCCAGAGCCAGCTGTGGCAGTTGATGCAACCAGCATTGCTCCTTGTGGGGAGGGTTTTCCTCAGTGTGACTTTGAAGACAACG CCCATCCCTTCTGTGACTGGGTCCAGACTTCCGGGGATGGTGGACACTGGGCCCTCGGACATAAAAATGGACCCGTCCATGGCATGGGCCCTGCGGGAGG TTTCCCTAATGCAGGGGGTCACTATATCTACCTTGAGGCTGACGAGTTCTCCCAGGCAGGCCAGTCAGTCAGACTGGTGAGCCGGCCCTTCTGCGCCCCA GGTGACATCTGCGTGGAGTTCGCATACCACATGTATGGCCTTGGGGAGGGTACTATGCTCGAACTCCTCCTGGGAAGTCCTGCGGGGAGTCCCCCGATTC CTCTCTGGAAACGCGTGGGGTCTCAGCGCCCTTACTGGCAGAACACCTCCGTCACCGTCCCCTCAGGACACCAACAGCCCATGCAGCTTATTTTCAAGGG CATCCAGGGAAGCAACACGGCCTCTGTGGTTGCTATGGGTTTCATCTTGATCAATCCTGGGACTTGTCCAGTAAAAGTGCTACCAGAGCTTCCTCCCGTA TCTCCAGTTTCTTCCACTGGCCCTTCTGAAACCACTGGCCTCACAGAAAACCCTACAATCTCCACCAAGAAACCTACAGTTTCCATAGAAAAACCCAGTG TCACCACAGAAAAGCCCACAGTCCCCAAAGAAAAGCCCACCATTCCCACAGAAAAACCCACCATCTCCACAGAAAAACCCACCATTCCTTCAGAAAAACC CAACATGCCCTCAGAAAAACCCACCATTCCCTCAGAAAAACCCACCATCCTCACAGAAAAACCCACCATTCCCTCAGAAAAACCCACCATTCCCTCAGAA AAACCCACCATTTCCACAGAAAAACCCACCGTCCCCACAGAAGAGCCCACCACCCCCACTGAGGAGACCACCACCTCCATGGAAGAGCCTGTCATCCCTA CAGAAAAACCCAGCATCCCTACAGAAAAACCCAGCATCCCCACGGAAAAACCCACCATCTCCATGGAAGAGACTATCATCTCCACAGAAAAACCCACCAT CTCCCCAGAAAAACCCACCATCCCCACAGAAAAACCCACCATCCCCACAGAAAAATCCACCATCTCCCCAGAAAAACCCACCACCCCCACAGAAAAACCC ACCATCCCCACAGAAAAACCCACCATCTCCCCAGAAAAACCCACCACCCCCACAGAAAAACCCACCATCTCCCCAGAAAAACTCACCATCCCCACAGAAA AACCCACCATCCCCACAGAAAAACCCACCATTCCCACAGAAAAACCCACCATCTCCACAGAAGAGCCCACCACCCCCACTGAGGAGACCACCATCTCCAC AGAAAAACCCAGCATCCCCATGGAAAAACCCACTCTCCCCACTGAAGAAACCACCACCTCTGTTGAAGAGACTACCATCTCTACAGAAAAACTCACCATC CCCATGGAAAAACCCACCATCTCCACAGAAAAACCCACCATCCCCACAGAAAAACCCACCATCTCCCCAGAAAAACTCACCATCCCCACGGAAAAACTCA CCATCCCCACGGAAAAACCCACCATCCCCATTGAAGAGACTACCATCTCCACAGAAAAACTCACCATCCCCACAGAAAAACCCACCATCTCCCCAGAAAA ACCCACCATCTCCACGGAAAAACCCACCATCCCCACGGAAAAACCCACCATCCCCACTGAAGAGACTACCATCTCCACAGAAAAACTCACCATCCCCACA GAAAAACCCACCATCTCCCCAGAAAAACTCACCATCCCCACAGAAAAACCCACCATCTCCACGGAAAAACCCACCATCCCCACGGAAAAACTTACCATCC CCACGGAAAAACCCACCATCCCCACAGAAAAACCCACCATTCCCACAGAGAAGCTCACAGCCCTGAGGCCACCCCATCCCAGCCCCACAGCCACTGGGCT GGCAGCCTTGGTGATGTCTCCACATGCTCCAAGTACCCCTATGACCAGTGTGATTCTGGGCACTACCACAACCTCCAGATCCAGTACAGAGCGCTGCCCT CCAAATGCCCGCTACGAATCCTGTGCTTGTCCTGCTTCGTGCAAGAGCCCCAGGCCTAGCTGTGGGCCCCTCTGTCGGGAGGGCTGTGTCTGCAACCCTG GCTTTTTGTTTAGTGACAACCACTGCATCCAGGCCTCTTCCTGCAATTGCTTCTACAACAACGACTACTATGAGCCTGGGGCAGAGTGGTTCAGCCCCAA CTGCACAGAACATTGCCGCTGCTGGCCCGGCAGTCGGGTCGAGTGCCAGATCTCTCAGTGTGGGACACACACCGTGTGCCAGCTTAAGAATGGCCAGTAT GGATGCCACCCCTACGCAGGCACTGCCACCTGCTTGGTCTACGGAGACCCTCATTATGTCACCTTTGACGGGAGGCACTTTGGCTTCATGGGCAAGTGCA CTTACATCTTGGCCCAGCCCTGTGGCAACTCAACAGACCCATTCTTCAGGGTGACAGCCAAGAATGAGGAGCAGGGACAGGAAGGCGTGTCCTGCCTGAG CAAAGTCTACGTGACCCTGCCCGAGAGCACCGTCACCCTGCTTAAGGGCAGACGCACTCTGGTTGGGGGTCAGCAAGTTACTCTCCCAGCCATACCCTCT AAAGGCGTCTTCCTGGGTGCAAGCGGGCGGTTTGTGGAGCTGCAGACGGAGTTCGGTTTGCGGGTGAGATGGGATGGTGACCAGCAGCTGTATGTTACTG TGTCCAGCACATACTCTGGCAAACTCTGTGGTTTGTGTGGGAACTATGACGGCAACAGTGACAATGACCACCTGAAGTTGGACGGCAGCCCAGCAGGAGA CAAGGAGGAGCTGGGGAACAGCTGGCAGACGGACCAGGACGAGGACCAGGAGTGTCAGAAGTACCAGGTGGTGAATTCCCCGTCTTGTGATTCATCTCTG CAGAGCAGCATGTCGGGGCCAGGGTTCTGTGGACGGCTGGTCGACACTCATGGCCCATTTGAGACATGCCTGCTGCACGTGAAGGCCGCTTCCTTCTTCG ACAGCTGCATGCTTGATATGTGCGGATTCCAGGGGCTGCAGCACCTGCTGTGCACACACATGTCCACCATGACCACCACCTGCCAGGACGCAGGCCACGC TGTGAAGCCCTGGAGGGAACCCCACTTCTGCCCAATGGCCTGCCCGCCCAACAGCAAGTACTCCCTGTGTGCGAAGCCATGCCCTGACACCTGCCATTCA GGATTCTCCGGCATGTTCTGCTCAGACCGGTGCGTGGAGGCCTGTGAATGCAATCCGGGCTTCGTCCTCAGTGGCCTCGAGTGCATACCTCGCTCCCAGT GTGGGTGCCTCCACCCTGCAGGCAGCTACTTCAAGGTAGGGGAGCGGTGGTACAAGCCAGGCTGCAAAGAGTTGTGCGTCTGTGAAAGCAACAACAGAAT TCGCTGCCAGCCCTGGAGGTGTAGGGCCCAGGAGTTCTGTGGCCAACAGGATGGTATCTATGGCTGCCATGCCCAAGGTGCCGCCACCTGCACAGCCTCG GGTGACCCCCACTACCTGACCTTCGATGGCGCCTTGCACCACTTCATGGGCACCTGCACCTATGTCCTGACCCGGCCTTGCTGGTCCAGGTCCCAAGACA GCTATTTTGTTGTGAGCGCCACCAACGAGAACCGCGGGGGGATCCTGGAGGTCTCCTACATCAAAGCCGTCCACGTGACAGTCTTTGACCTCAGCATCTC ACTGCTCAGAGGCTGTAAGGTCATGCTGAATGGCCATCGGGTGGCCCTACCTGTGTGGCTTGCACAAGGCCGGGTGACCATAAGGCTCAGCAGCAACCTC GTCCTCCTCTACACGAACTTTGGGCTCCAAGTTCGCTACGACGGGAGCCACTTGGTGGAAGTGACAGTCCCCTCCTCCTATGGCGGCCAGCTCTGTGGGC TGTGTGGGAACTACAACAACAACAGCTTGGATGACAACCTGCGCCCCGACAGAAAGCTTGCAGGCGATTCCATGCAGCTGGGGGCCGCCTGGAAGTTACC TGAATCCTCTGAACCTGGCTGTTTCCTTGTGGGTGGCAAGCCCTCCAGCTGCCAGGAGAACAGCATGGCAGACGCCTGGAACAAGAACTGTGCGATCTTA ATAAACCCTCAGGGACCCTTCTCTCAATGTCACCAGGTGGTGCCTCCCCAGTCCAGCTTTGCCAGTTGCGTGCATGGTCAGTGTGGGACCAAGGGCGACA CCACAGCCCTGTGCCGCTCCCTGCAGGCCTACGCGTCCCTGTGTGCCCAGGCTGGCCAGGCCCCTGCCTGGCGGAACAGAACCTTCTGCCCTATGAGGTG CCCACCTGGCAGCAGCTACAGCCCCTGCAGCAGCCCCTGCCCAGACACCTGCAGCAGCATAAACAACCCGAGGGACTGCCCCAAAGCACTGCCCTGTGCT GAGAGCTGTGAATGTCAGAAAGGCCACATCTTGAGTGGAACCTCCTGCGTGCCCCTTGGCCAGTGTGGCTGCACTGACCCAGCGGGCTCCTACCACCCGG TCGGGGAGCGCTGGTACACAGAGAACACCTGCACCAGGCTCTGCACCTGCTCCGTCCACAACAACATCACCTGCTTCCAGAGCACCTGCAAACCCAACCA GATATGCTGGGCCCTGGATGGGCTGCTCCGTTTCGGGCCTCAGGTGTGGGAGTGTGTCAGCTCCCAGGGGAGTCCCACTACGTGAGCTTTGATGGTAGTA ACCATTCTATCCCGGACGCCTGCACTCTTGTCCTGGTGAAAGTGTGCCACCCCGCCATGGCCTTGCCCTTCTTCAAGATCAGTGCCAAGCATGAGAAGGA GGAAGGTGGAACTGAGGCTTTCCGCCTTCATGAGGTCTACATTGACATCTACGATGCCCAGGTCACCCTGCAGAAGGGCCACCGTGTGCTAATCAACAGC AAACAGGTCACCCTCCCCGCCATCTCCCAGATCCCTGGGGTCAGTGTCAAGTCCAGCAGCATCTACAGCATTGTTAACATCAAGATCGGGGTGCAAGTCA AGTTTGACGGGAATCATCTCTTAGAGATTGAAATCCCCACAACCTACTATGGAAAGGTCTGCGGCATGTGTGGGAACTTCAATGATGAGGAAGAGGACGA ACTAATGATGCCCAGCGATGAAGTAGCAAATAGTGACAGTGAATTTGTGAACAGTTGGAAAGATAAGGACATTGACCCAAGTTGTCAGAGTCTCCTGGTA GATGAGCAGCAGATTCCAGCGGAACAGCAGGAGAACCCGAGTGGAAACTGCAGGGCGGCCGACCTCCGCAGGGCGCGGGAAAAGTGCGAGGCAGCGCTCC GGGCTCCTGTGTGGGCCCAGTGCGCCTCCCGCATAGACCTCACGCCCTTCCTGGTGGACTGTGCAAACACCCTCTGTGAGTTCGGAGGTCTCTACCAGGC CCTCTGCCAGGCTCTGCAAGCCTTCGGGGCCACCTGCCAGAGCCAGGGGCTCAAGCCCCCACTCTGGAGAAACAGCAGCTTCTGCCCTCTGGAATGCCCT GCCTACAGCAGCTACACCAACTGCCTTCCCTCCTGCTCACCCTCCTGCTGGGACCTGGATGGCCGGTGTGAGGGCGCCAAAGTCCCCTCTGCCTGCGCTG AGGGCTGCATTTGTCAGCCCGGCTATGTGCTGAGTGAAGACAAGTGTGTCCCCAGAAGTCAGTGTGGCTGCAAGGATGCCCATGGTGGCTCCATCCCTCT GGGCAAGAGCTGGGTCTCCAGCGGTTGCACGGAGAAGTGTGTCTGCACGGGAGGAGCCATTCAGTGCGGGGACTTCCGATGCCCCTCTGGGTCCCACTGC CAGCTCACTTCCGACAACAGCAACAGCAATTGTGTCTCAGACAAGTCTGAACAATGCTCAGTCTATGGCGACCCCCGTTACCTCACATTTGACGGCTTCA GCTACCGCTTGCAAGGCCGCATGACCTATGTTCTGATCAAGACTGTGGACGTACTGCCTGAGGGGGTGGAGCCCCTCCTCGTGGAAGGACGCAACAAGAT GGATCCGCCCAGGAGCTCCATCTTCTTGCAGGAAGTGATTACCACCGTCTACGGCTATAAAGTGCAGCTCCAAGCTGGTCTGGAGCTTGTGGTCAACAAC CAGAAGATGGCCGTCCCCTACAGGCCAAATGAACACCTGCGGGTCACCCTGTGGGGCCAACGGCTCTACCTGGTCACCGACTTTGAGCTGGTCGTCAGCT TTGGTGGAAGGAAAAATGCAGTGATCTCCCTACCCAGCATGTACGAGGGGCTTGTGAGTGGCCTGTGCGGAAACTACGACAAGAACCGCAAGAATGACAT GATGCTGCCCAGTGGCGCCCTGACCCAGAACCTCAACACCTTTGGCAACAGCTGGGAGGTGAAGACCGAGGACGCACTCCTGCGCTTCCCCAGGGCTATA CCAGCGGAGGAGGAGGGACAAGGGGCGGAGCTGGGCCTCCGCACGGGCCTCCAAGTGTCCGAATGTAGCCCGGAGCAGCTGGCGAGCAACAGCACCCAGG CCTGTAGGGTGCTGGCAGACCCCCAGGGCCCCTTTGCTGCCTGTCACCAGACGGTGGCCCCAGAGCCCTTCCAAGAGCACTGCGTGCTGGATCTGTGCTC TGCTCAGGACCCAAGAGAGCAAGAGGAGCTGCGTTGCCAGGTCCTCAGTGGCCATGGAGTGTCCAGCAGGTACCATATATCAGAGCTGTATGACACCCTG CCCAGCATCCTGTGCCAACCTGGCAGACCCCGGGGACTGCGAGGGCCCCTGCGTGGAAGGCTGCGCCAGCATCCCAGGCTATGCCTACAGTGGCACCCAG AGCCTCCCCTGGCTGACTGTGGCTGCACCAGCAATGGCATCTACTACCAGCTGGGCAGCAGCTTTCTGACTGAGGACTGCTCTCAGCGGTGCACCTGTGC CAGCTCACGGATCCTGCTGTGTGAGCCCTTCAGCTGCAGAGCGGGGGAGGTCTGCACCCTGGGGAACCACACCCAAGGCTGCTTTCCAGAAAGCCCGTGT CTGCAGAACCCCTGTCAGAATGACGGGCAGTGTCGGGAGCAGGGAGCCACCTTCACCTGCGAGTGTGAAGTTGGTTACGGGGGAGGCCTGTGTATGGAGC CTCGAGATGCGCCACCTCCCAGAAAGCCAGCATCTAACCTGGTGGGCGTCCTACTGGGACTGCTGGTGCCTGTGGTGGTCGTACTACTGGCCGTGACCAG AGAGTGCATTTACAGAACGAGGAGGAAGAGAGAGAAAACGCAGGAGGGAGACAGACTGGCCAGGCTGGTGGACACAGATACTGTTCTGGACTGTGCCTGT TAAGTTGCTCAGTTTTGAGCTGTCTTCAGACAAGAAGATTAAATAAATTTATATATTTATTTATTTGA

refseq_ZAN.F1 (forward primer)
refseq_ZAN.R1 (reverse primer)
Exon skipping and alternative donor or acceptor

Frame 0

AMLISDP*AFLCFSVHSSWHPWKDAKLRRPGGN KRSPGSQLCPSPLPWEQPLRVLMVPPVWTLLLLV GAALFRKEKPPDQKLVVRSSRDNYVLTQCDFED DAKPLCDWSQVSADDEDWVRASGPSPTGSTGAP GGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQ GPLCVHFAHHMFGLSWGAQLRLLLLSGEEGRRP DVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMF EGTRGSTAYLDIALDALSIRRGSCNRVCMMQTCS FDIPNDLCDWTWIPTASGAKWTQKKGSSGKPGV GPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSP VSLSSGCLSFSFHYILRGQSPGAALHIYASVLGS IRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVV GVFGKTPEPAVAVDATSIAPCGEGFPQCDFEDN AHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGG FPNAGGHYIYLEADEFSQAGQSVRLVSRPFCAP GDICVEFAYHMYGLGEGTMLELLLGSPAGSPPI PLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKG IQGSNTASVVAMGFILINPGTCPVKVLPELPPV SPVSSTGPSETTGLTENPTISTKKPTVSIEKPS VTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKP NMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIP TEKPSIPTEKPSIPTEKPTISMEETIISTEKPTI SPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP TIPTEKPTISPEKPTTPTEKPTISPEKLTIPTE KPTIPTEKPTIPTEKPTISTEEPTTPTEETTIST EKPSIPMEKPTLPTEETTTSVEETTISTEKLTI PMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEK PTISTEKPTIPTEKPTIPTEETTISTEKLTIPT EKPTISPEKLTIPTEKPTISTEKPTIPTEKLTI PTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGL AALVMSPHAPSTPMTSVILGTTTTSRSSTERCP PNARYESCACPASCKSPRPSCGPLCREGCVCNP GFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPN CTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKC TYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLS KVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS KGVFLGASGRFVELQTEFGLRVRWDGDQQLYVT VSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGD KEELGNSWQTDQDEDQECQKYQVVNSPSCDSSL QSSMSGPGFCGRLVDTHGPFETCLLHVKAASFF DSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHA VKPWREPHFCPMACPPNSKYSLCAKPCPDTCHS GFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ CGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTAS GDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQD SYFVVSATNENRGGILEVSYIKAVHVTVFDLSIS LLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNL VLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCG LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLP ESSEPGCFLVGGKPSSCQENSMADAWNKNCAIL INPQGPFSQCHQVVPPQSSFASCVHGQCGTKGD TTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC PPGSSYSPCSSPCPDTCSSINNPRDCPKALPCA ESCECQKGHILSGTSCVPLGQCGCTDPAGSYHP VGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQ ICWALDGLLRFGPQVWECVSSQGSPTT*ALMVV TILSRTPALLSW*KCATPPWPCPSSRSVPSMRR RKVELRLSAFMRSTLTSTMPRSPCRRATVC*STA NRSPSPPSPRSLGSVSSPAASTALLTSRSGCKS SLTGIIS*RLKSPQPTMERSAACVGTSMMRKRT N**CPAMK*QIVTVNL*TVGKIRTLTQVVRVSW* MSSRFQRNSRRTRVETAGRPTSAGRGKSARQRS GLLCGPSAPPA*TSRPSWWTVQTPSVSSEVSTR PSARLCKPSGPPARARGSSPHSGETAASALWNAL PTAATPTAFPPAHPPAGTWMAGVRAPKSPLPAL RAAFVSPAMC*VKTSVSPEVSVAARMPMVAPSL WARAGSPAVARRSVSAREEPFSAGTSDAPLGPTA SSLPTTATAIVSQTSLNNAQSMATPVTSHLTAS ATACKAA*PMF*SRLWTYCLRGWSPSSWKDATR WIRPGAPSSCRK*LPPSTAIKCSSKLVWSLWSTT RRWPSPTGQMNTCGSPCGANGSTWSPTLSWSSA LVEGKMQ*SPYPACTRGL*VACAETTTRTARMT *CCPVAP*PRTSTPLATAGR*RPRTHSCASPGLY QRRRRDKGRSWASARASKCPNVARSSWRATAPR PVGCWQTPRAPLLPVTRRWPQSPSKSTACWICA LLRTQESKRSCVARSSVAMECPAGTIYQSCMTPC PASCANLADPGDCEGPCVEGCASIPGYAYSGTQ SLPWLTVAAPAMASTTSWAAAF*LRTALSGAPV PAHGSCCVSPSAAERGRSAPWGTTPKAAFQKARV CRTPVRMTGSVGSREPPSPASVKLVTGEACVWS LEMRHLPESQHLTWWASYWDCWCLWWSYYWP*P ESAFTERGGRERKRRRETDWPGWWTQILFWTVPV KLLSFELSSDKKIK*IYIFIYL

Frame 1

PC*FLILELFCVSLFILHGILGRMPS*GGQGGI KGVQAPNCALPLSPGSNHLGSSWFLQSGLCCFW WGLPFSGKRSLRTRSWLFAALGTTMSSPSVILRM TPNPSVTGPKCPQTMKTGFEPVGPLPPAPPGPP GGTLTERAAICIWNRTASTVGEWPACSAPTYGS KAPSVCTLPTTCSGCLGAPSSGCCCSRVKRAAAP MCSGNTGTPRDPPGCSPPSLCPQGSPCPPG*CL REHGVALPTWTSPWMPSLSAGAPVIASV*CKHA ALTFQMTSVTGPGSQLPPGPSGLRRKGHQESQAW GLMATSLALVVAATCSWTPRMQDLGRKLSS*AP *ACPLAV*AFPSTTSSGASLLVQPSTFMLQSWG VSGNTLSSQDNLGPTGRLFLSITQPWDGYSLPW* AFLERPQSQLWQLMQPALLLVGRVFLSVTLKTT PIPSVTGSRLPGMVDTGPSDIKMDPSMAWALRE VSLMQGVTISTLRLTSSPRQASQSDW*AGPSAPQ VTSAWSSHTTCMALGRVLCSNSSWEVLRGVPRF LSGNAWGLSALTGRTPPSPSPQDTNSPCSLFSR ASREATRPLWLLWVSS*SILGLVQ*KCYQSFLPY LQFLPLALLKPLASQKTLQSPPRNLQFP*KNPV SPQKSPQSPKKSPPFPQKNPPSPQKNPPFLQKN PTCPQKNPPFPQKNPPSSQKNPPFPQKNPPFPQK NPPFPQKNPPSPQKSPPPPLRRPPPPWKSLSSL QKNPASLQKNPASPRKNPPSPWKRLSSPQKNPP SPQKNPPSPQKNPPSPQKNPPSPQKNPPPPQKNP PSPQKNPPSPQKNPPPPQKNPPSPQKNSPSPQK NPPSPQKNPPFPQKNPPSPQKSPPPPLRRPPSP QKNPASPWKNPLSPLKKPPPLLKRLPSLQKNSPS PWKNPPSPQKNPPSPQKNPPSPQKNSPSPRKNS PSPRKNPPSPLKRLPSPQKNSPSPQKNPPSPQK NPPSPRKNPPSPRKNPPSPLKRLPSPQKNSPSPQ KNPPSPQKNSPSPQKNPPSPRKNPPSPRKNLPS PRKNPPSPQKNPPFPQRSSQP*GHPIPAPQPLG WQPW*CLHMLQVPL*PV*FWALPQPPDPVQSAAL QMPATNPVLVLLRARAPGLAVGPSVGRAVSATL AFCLVTTTASRPLPAIASTTTTTMSLGQSGSAP TAQNIAAAGPAVGSSARSLSVGHTPCASLRMASM DATPTQALPPAWSTETLIMSPLTGGTLASWASA LTSWPSPVATQQTHSSG*QPRMRSRDRKACPA* AKST*PCPRAPSPCLRADALWLGVSKLLSQPYPL KASSWVQAGGLWSCRRSSVCG*DGMVTSSCMLL CPAHTLANSVVCVGTMTATVTMTT*SWTAAQQE TRRSWGTAGRRTRTRTRSVRSTRW*IPRLVIHLC RAACRGQGSVDGWSTLMAHLRHACCT*RPLPSS TAACLICADSRGCSTCCAHTCPP*PPPARTQAT L*SPGGNPTSAQWPARPTASTPCVRSHALTPAIQ DSPACSAQTGAWRPVNAIRASSSVASSAYLAPS VGASTLQAATSR*GSGGTSQAAKSCASVKATTE FAASPGGVGPRSSVANRMVSMAAMPKVPPPAQPR VTPTT*PSMAPCTTSWAPAPMS*PGLAGPGPKT AILL*APPTRTAGGSWRSPTSKPST*QSLTSAS HCSEAVRSC*MAIGWPYLCGLHKAG*P*GSAATS SSSTRTLGSKFATTGATWWK*QSPPPMAASSVG CVGTTTTTAWMTTCAPTESLQAIPCSWGPPGSY LNPLNLAVSLWVASPPAARRTAWQTPGTRTVRS* *TLRDPSLNVTRWCLPSPALPVACMVSVGPRAT PQPCAAPCRPTRPCVPRLARPLPGGTEPSAL*G AHLAAATAPAAAPAQTPAAA*TTRGTAPKHCPVL RAVNVRKATS*VEPPACPLASVAALTQRAPTTR SGSAGTQRTPAPGSAPAPSTTTSPASRAPANPT RYAGPWMGCSVSGLRCGSVSAPRGVPLREL*W** PFYPGRLHSCPGESVPPRHGLALLQDQCQA*EG GRWN*GFPPS*GLH*HLRCPGHPAEGPPCANQQ QTGHPPRHLPDPWGQCQVQQHLQHC*HQDRGASQ V*RESSLRD*NPHNLLWKGLRHVWELQ**GRGR TNDAQR*SSK**Q*ICEQLER*GH*PKLSESPG R*AADSSGTAGEPEWKLQGGRPPQGAGKVRGSAP GSCVGPVRLPHRPHALPGGLCKHPL*VRRSLPG PLPGSASLRGHLPEPGAQAPTLEKQQLLPSGMP CLQQLHQLPSLLLTLLLGPGWPV*GRQSPLCLR* GLHLSARLCAE*RQVCPQKSVWLQGCPWWLHPS GQELGLQRLHGEVCLHGRSHSVRGLPMPLWVPL PAHFRQQQQQLCLRQV*TMLSLWRPPLPHI*RLQ LPLARPHDLCSDQDCGRTA*GGGAPPRGRTQQD GSAQELHLLAGSDYHRLRL*SAAPSWSGACGQQ PEDGRPLQAK*TPAGHPVGPTALPGHRL*AGRQL WWKEKCSDLPTQHVRGACEWPVRKLRQEPQE*H DAAQWRPDPEPQHLWQQLGGEDRGRTPALPQGY TSGGGGTRGGAGPPHGPPSVRM*PGAAGEQQHPG L*GAGRPPGPLCCLSPDGGPRALPRALRAGSVL CSGPKRARGAALPGPQWPWSVQQVPYIRAV*HP AQHPVPTWQTPGTARAPAWKAAPASQAMPTVAPR ASPG*LWLHQQWHLLPAGQQLSD*GLLSAVHLC QLTDPAV*ALQLQSGGGLHPGEPHPRLLSRKPV SAEPLSE*RAVSGAGSHLHLRV*SWLRGRPVYGA SRCATSQKASI*PGGRPTGTAGACGGRTTGRDQ RVHLQNEEEERENAGGRQTGQAGGHRYCSGLCL LSCSVLSCLQTRRLNKFIYLFI*

Frame 2

HVDF*SLSFSVFLCSFFMASLEGCQAKEARGE* KESRLPTVPFPSPLGATT*GPHGSSSLDSAASG GGCPFQEREASGPEAGCSQL*GQLCPHPV*F*G *RQTPL*LVPSVRRR*RLGSSQWALSHRLHRGPR GVP*RRGQLSAYGIEQLPPWGSGPPAQPRPMGA RPPLCALCPPHVRAVLGRPAQAAAALG*RGPPP RCALETLEHPETLLDAHHRHCARRVHPAHPADV* GNTG*HCLPGHRPGCPLYPPGLL*SRLYDANMQ L*HSK*PL*LDLDPNCLRGQVDSEERVIRKARR GA*WRLL*PW*WLLHAPGPQECKTWAESCPPEPR EPVLWLSELFLPLHPPGPVSWCSPPHLCFSLGE YPETHSLLRTTWAQLAGCFCQLHSRGTDTVCRG RRFWKDPRASCGS*CNQHCSLWGGFSSV*L*RQR PSLL*LGPDFRGWWTLGPRT*KWTRPWHGPCGR FP*CRGSLYLP*G*RVLPGRPVSQTGEPALLRP R*HLRGVRIPHVWPWGGYYARTPPGKSCGESPDS SLETRGVSAPLLAEHLRHRPLRTPTAHAAYFQG HPGKQHGLCGCYGFHLDQSWDLSSKSATRASSR ISSFFHWPF*NHWPHRKPYNLHQETYSFHRKTQC HHRKAHSPQRKAHHSHRKTHHLHRKTHHSFRKT QHALRKTHHSLRKTHHPHRKTHHSLRKTHHSLR KTHHFHRKTHRPHRRAHHPH*GDHHLHGRACHPY RKTQHPYRKTQHPHGKTHHLHGRDYHLHRKTHH LPRKTHHPHRKTHHPHRKIHHLPRKTHHPHRKT HHPHRKTHHLPRKTHHPHRKTHHLPRKTHHPHRK THHPHRKTHHSHRKTHHLHRRAHHPH*GDHHLH RKTQHPHGKTHSPH*RNHHLC*RDYHLYRKTHH PHGKTHHLHRKTHHPHRKTHHLPRKTHHPHGKTH HPHGKTHHPH*RDYHLHRKTHHPHRKTHHLPRK THHLHGKTHHPHGKTHHPH*RDYHLHRKTHHPH RKTHHLPRKTHHPHRKTHHLHGKTHHPHGKTYHP HGKTHHPHRKTHHSHREAHSPEATPSQPHSHWA GSLGDVSTCSKYPYDQCDSGHYHNLQIQYRALP SKCPLRILCLSCFVQEPQA*LWAPLSGGLCLQPW LFV**QPLHPGLFLQLLLQQRLL*AWGRVVQPQ LHRTLPLLARQSGRVPDLSVWDTHRVPA*EWPV WMPPLRRHCHLLGLRRPSLCHL*REALWLHGQVH LHLGPALWQLNRPILQGDSQE*GAGTGRRVLPE QSLRDPAREHRHPA*GQTHSGWGSASYSPSHTL *RRLPGCKRAVCGAADGVRFAGEMGW*PAAVCYC VQHILWQTLWFVWEL*RQQ*Q*PPEVGRQPSRR QGGAGEQLADGPGRGPGVSEVPGGEFPVL*FIS AEQHVGARVLWTAGRHSWPI*DMPAAREGRFLLR QLHA*YVRIPGAAAPAVHTHVHHDHHLPGRRPR CEALEGTPLLPNGLPAQQQVLPVCEAMP*HLPF RILRHVLLRPVRGGL*MQSGLRPQWPRVHTSLPV WVPPPCRQLLQGRGAVVQARLQRVVRL*KQQQN SLPALEV*GPGVLWPTGWYLWLPCPRCRHLHSL G*PPLPDLRWRLAPLHGHLHLCPDPALLVQVPRQ LFCCERHQREPRGDPGGLLHQSRPRDSL*PQHL TAQRL*GHAEWPSGGPTCVACTRPGDHKAQQQP RPPLHELWAPSSLRREPLGGSDSPLLLWRPALWA VWELQQQQLG*QPAPRQKACRRFHAAGGRLEVT *IL*TWLFPCGWQALQLPGEQHGRRLEQELCDL NKPSGTLLSMSPGGASPVQLCQLRAWSVWDQGRH HSPVPLPAGLRVPVCPGWPGPCLAEQNLLPYEV PTWQQLQPLQQPLPRHLQQHKQPEGLPQSTALC *EL*MSERPHLEWNLLRAPWPVWLH*PSGLLPPG RGALVHREHLHQALHLLRPQQHHLLPEHLQTQP DMLGPGWAAPFRASGVGVCQLPGESHYVSFDGS NHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE EGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINS KQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQV KFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLV DEQQIPAEQQENPSGNCRAADLRRAREKCEAAL RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQA LCQALQAFGATCQSQGLKPPLWRNSSFCPLECP AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACA EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL GKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHC QLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGF SYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKM DPPRSSIFLQEVITTVYGYKVQLQAGLELVVNN QKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVS FGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDM MLPSGALTQNLNTFGNSWEVKTEDALLRFPRAI PAEEEGQGAELGLRTGLQVSECSPEQLASNSTQ ACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCS AQDPREQEELRCQVLSGHGVSSRYHISELYDTL PSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHP EPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCA SSRILLCEPFSCRAGEVCTLGNHTQGCFPESPC LQNPCQNDGQCREQGATFTCECEVGYGGGLCME PRDAPPPRKPASNLVGVLLGLLVPVVVVLLAVTR ECIYRTRRKREKTQEGDRLARLVDTDTVLDCAC *VAQF*AVFRQED*INLYIYLF