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Sequences

Sequence NM_153202

GCTGCACCGGGCACGGGTCGGCCGCAATCCAGCCTGGGCGGAGCCGGAGTTGCGAGCCGCTGCCTAGAGGCCGAGGAGCTCACAGCTATGGGCTGGAGGC CCCGGAGAGCTCGGGGGACCCCGTTGCTGCTGCTGCTACTACTGCTGCTGCTCTGGCCAGTGCCAGGCGCCGGGGTGCTTCAAGGACATATCCCTGGGCA GCCAGTCACCCCGCACTGGGTCCTGGATGGACAACCCTGGCGCACCGTCAGCCTGGAGGAGCCGGTCTCGAAGCCAGACATGGGGCTGGTGGCCCTGGAG GCTGAAGGCCAGGAGCTCCTGCTTGAGCTGGAGAAGAACCACAGGCTGCTGGCCCCAGGATACATAGAAACCCACTACGGCCCAGATGGGCAGCCAGTGG TGCTGGCCCCCAACCACACGGATCATTGCCACTACCAAGGGCGAGTAAGGGGCTTCCCCGACTCCTGGGTAGTCCTCTGCACCTGCTCTGGGATGAGTGG CCTGATCACCCTCAGCAGGAATGCCAGCTATTATCTGCGTCCCTGGCCACCCCGGGGCTCCAAGGACTTCTCAACCCACGAGATCTTTCGGATGGAGCAG CTGCTCACCTGGAAAGGAACCTGTGGCCACAGGGATCCTGGGAACAAAGCGGGCATGACCAGCCTTCCTGGTGGTCCCCAGAGCAGGGGCAGGCGAGAAG CGCGCAGGACCCGGAAGTACCTGGAACTGTACATTGTGGCAGACCACACCCTGTTCTTGACTCGGCACCGAAACTTGAACCACACCAAACAGCGTCTCCT GGAAGTCGCCAACTACGTGGACCAGCTTCTCAGGACTCTGGACATTCAGGTGGCGCTGACCGGCCTGGAGGTGTGGACCGAGCGGGACCGCAGCCGCGTC ACGCAGGACGCCAACGCCACGCTCTGGGCCTTCCTGCAGTGGCGCCGGGGGCTGTGGGCGCAGCGGCCCCACGACTCCGCGCAGCTGCTCACGGGCCGCG CCTTCCAGGGCGCCACAGTGGGCCTGGCGCCCGTCGAGGGCATGTGCCGCGCCGAGAGCTCGGGAGGCGTGAGCACGGACCACTCGGAGCTCCCCATCGG CGCCGCAGCCACCATGGCCCATGAGATCGGCCACAGCCTCGGCCTCAGCCACGACCCCGACGGCTGCTGCGTGGAGGCTGCGGCCGAGTCCGGAGGCTGC GTCATGGCTGCGGCCACCGGGCACCCGTTTCCGCGCGTGTTCAGCGCCTGCAGCCGCCGCCAGCTGCGCGCCTTCTTCCGCAAGGGGGGCGGCGCTTGCC TCTCCAATGCCCCGGACCCCGGACTCCCGGTGCCGCCGGCGCTCTGCGGGAACGGCTTCGTGGAAGCGGGCGAGGAGTGTGACTGCGGCCCTGGCCAGGA GTGCCGCGACCTCTGCTGCTTTGCTCACAACTGCTCGCTGCGCCCGGGGGCCCAGTGCGCCCACGGGGACTGCTGCGTGCGCTGCCTGCTGAAGCCGGCT GGAGCGCTGTGCCGCCAGGCCATGGGTGACTGTGACCTCCCTGAGTTTTGCACGGGCACCTCCTCCCACTGTCCCCCAGACGTTTACCTACTGGACGGCT CACCCTGTGCCAGGGGCAGTGGCTACTGCTGGGATGGCGCATGTCCCACGCTGGAGCAGCAGTGCCAGCAGCTCTGGGGGCCTGGCTCCCACCCAGCTCC CGAGGCCTGTTTCCAGGTGGTGAACTCTGCGGGAGATGCTCATGGAAACTGCGGCCAGGACAGCGAGGGCCACTTCCTGCCCTGTGCAGGGAGGGATGCC CTGTGTGGGAAGCTGCAGTGCCAGGGTGGAAAGCCCAGCCTGCTCGCACCGCACATGGTGCCAGTGGACTCTACCGTTCACCTAGATGGCCAGGAAGTGA CTTGTCGGGGAGCCTTGGCACTCCCCAGTGCCCAGCTGGACCTGCTTGGCCTGGGCCTGGTAGAGCCAGGCACCCAGTGTGGACCTAGAATGGTTTGCAA TAGCAACCATAACTGCCACTGTGCTCCAGGCTGGGCTCCACCCTTCTGTGACAAGCCAGGCTTTGGTGGCAGCATGGACAGTGGCCCTGTGCAGGCTGAA AACCATGACACCTTCCTGCTGGCCATGCTCCTCAGCGTCCTGCTGCCTCTGCTCCCAGGGGCCGGCCTGGCCTGGTGTTGCTACCGACTCCCAGGAGCCC ATCTGCAGCGATGCAGCTGGGGCTGCAGAAGGGACCCTGCGTGCAGTGGCCCCAAAGATGGCCCACACAGGGACCACCCCCTGGGCGGCGTTCACCCCAT GGAGTTGGGCCCCACAGCCACTGGACAGCCCTGGCCCCTGGACCCTGAGAACTCTCATGAGCCCAGCAGCCACCCTGAGAAGCCTCTGCCAGCAGTCTCG CCTGACCCCCAAGCAGATCAAGTCCAGATGCCAAGATCCTGCCTCTGGTGAGAGGTAGCTCCTAAAATGAACAGATTTAAAGACAGGTGGCCACTGACAG CCACTCCAGGAACTTGAACTGCAGGGGCAGAGCCAGTGAATCACCGGACCTCCAGCACCTGCAGGCAGCTTGGAAGTTTCTTCCCCGAGTGGAGCTTCGA CCCACCCACTCCAGGAACCCAGAGCCACATTAGAAGTTCCTGAGGGCTGGAGAACACTGCTGGGCACACTCTCCAGCTCAATAAACCATCAGTCCCAGAA GCAAAGGTCACACAGCCCCTGACCTCCCTCACCAGTGGAGGCTGGGTAGTGCTGGCCATCCCAAAAGGGCTCTGTCCTGGGAGTCTGGTGTGTCTCCTAC ATGCAATTTCCACGGACCCAGCTCTGTGGAGGGCATGACTGCTGGCCAGAAGCTAGTGGTCCTGGGGCCCTATGGTTCGACTGAGTCCACACTCCCCTGG AGCCTGGCTGGCCTCTGCAAACAAACATAATTTTGGGGACCTTCCTTCCTGTTTCTTCCCACCCTGTCTTCTCCCCTAGGTGGTTCCTGAGCCCCCACCC CCAATCCCAGTGCTACACCTGAGGTTCTGGAGCTCAGAATCTGACAGCCTCTCCCCCATTCTGTGTGTGTCGGGGGGACAGAGGGAACCATTTAAGAAAA GATACCAAAGTAGAAGTCAAAAGAAAGACATGTTGGCTATAGGCGTGGTGGCTCATGCCTATAATCCCAGCACTTTGGGAAGCCGGGGTAGGAGGATCAC CAGAGGCCAGCAGGTCCACACCAGCCTGGGCAACACAGCAAGACACCGCATCTACAGAAAAATTTTAAAATTAGCTGGGCGTGGTGGTGTGTACCTGTAG GCCTAGCTGCTCAGGAGGCTGAAGCAGGAGGATCACTTGAGCCTGAGTTCAACACTGCAGTGAGCTATGGTGGCACCACTGCACTCCAGCCTGGGTGACA GAGCAAGACCCTGTCTCTAAAATAAATTTTAAAAAGACATA

refseq_ADAM33.F1 (forward primer)
refseq_ADAM33.R1 (reverse primer)
Single exon skipping

Frame 0

AAPGTGRPQSSLGGAGVASRCLEAEELTAMGWR PRRARGTPLLLLLLLLLLWPVPGAGVLQGHIPGQ PVTPHWVLDGQPWRTVSLEEPVSKPDMGLVALE AEGQELLLELEKNHRLLAPGYIETHYGPDGQPV VLAPNHTDHCHYQGRVRGFPDSWVVLCTCSGMSG LITLSRNASYYLRPWPPRGSKDFSTHEIFRMEQ LLTWKGTCGHRDPGNKAGMTSLPGGPQSRGRRE ARRTRKYLELYIVADHTLFLTRHRNLNHTKQRLL EVANYVDQLLRTLDIQVALTGLEVWTERDRSRV TQDANATLWAFLQWRRGLWAQRPHDSAQLLTGR AFQGATVGLAPVEGMCRAESSGGVSTDHSELPIG AAATMAHEIGHSLGLSHDPDGCCVEAAAESGGC VMAAATGHPFPRVFSACSRRQLRAFFRKGGGAC LSNAPDPGLPVPPALCGNGFVEAGEECDCGPGQE CRDLCCFAHNCSLRPGAQCAHGDCCVRCLLKPA GALCRQAMGDCDLPEFCTGTSSHCPPDVYLLDG SPCARGSGYCWDGACPTLEQQCQQLWGPGSHPAP EACFQVVNSAGDAHGNCGQDSEGHFLPCAGRDA LCGKLQCQGGKPSLLAPHMVPVDSTVHLDGQEV TCRGALALPSAQLDLLGLGLVEPGTQCGPRMVCN SNHNCHCAPGWAPPFCDKPGFGGSMDSGPVQAE NHDTFLLAMLLSVLLPLLPGAGLAWCCYRLPGA HLQRCSWGCRRDPACSGPKDGPHRDHPLGGVHPM ELGPTATGQPWPLDPENSHEPSSHPEKPLPAVS PDPQADQVQMPRSCLW*EVAPKMNRFKDRWPLT ATPGT*TAGAEPVNHRTSSTCRQLGSFFPEWSFD PPTPGTQSHIRSS*GLENTAGHTLQLNKPSVPE AKVTQPLTSLTSGGWVVLAIPKGLCPGSLVCLL HAISTDPALWRA*LLARS*WSWGPMVRLSPHSPG AWLASANKHNFGDLPSCFFPPCLLP*VVPEPPP PIPVLHLRFWSSESDSLSPILCVSGGQREPFKK RYQSRSQKKDMLAIGVVAHAYNPSTLGSRGRRIT RGQQVHTSLGNTARHRIYRKILKLAGRGGVYL* A*LLRRLKQEDHLSLSSTLQ*AMVAPLHSSLGD RARPCL*NKF*KDI

Frame 1

LHRARVGRNPAWAEPELRAAA*RPRSSQLWAGG PGELGGPRCCCCYYCCCSGQCQAPGCFKDISLG SQSPRTGSWMDNPGAPSAWRSRSRSQTWGWWPWR LKARSSCLSWRRTTGCWPQDT*KPTTAQMGSQW CWPPTTRIIATTKGE*GASPTPG*SSAPALG*V A*SPSAGMPAIICVPGHPGAPRTSQPTRSFGWSS CSPGKEPVATGILGTKRA*PAFLVVPRAGAGEK RAGPGSTWNCTLWQTTPCS*LGTET*TTPNSVS WKSPTTWTSFSGLWTFRWR*PAWRCGPSGTAAAS RRTPTPRSGPSCSGAGGCGRSGPTTPRSCSRAA PSRAPQWAWRPSRACAAPRAREA*ARTTRSSPS APQPPWPMRSATASASATTPTAAAWRLRPSPEAA SWLRPPGTRFRACSAPAAAASCAPSSARGAALA SPMPRTPDSRCRRRSAGTASWKRARSVTAALAR SAATSAALLTTARCARGPSAPTGTAACAAC*SRL ERCAARPWVTVTSLSFARAPPPTVPQTFTYWTA HPVPGAVATAGMAHVPRWSSSASSSGGLAPTQL PRPVSRW*TLREMLMETAARTARATSCPVQGGMP CVGSCSARVESPACSHRTWCQWTLPFT*MARK* LVGEPWHSPVPSWTCLAWAW*SQAPSVDLEWFA IATITATVLQAGLHPSVTSQALVAAWTVALCRLK TMTPSCWPCSSASCCLCSQGPAWPGVATDSQEP ICSDAAGAAEGTLRAVAPKMAHTGTTPWAAFTP WSWAPQPLDSPGPWTLRTLMSPAATLRSLCQQSR LTPKQIKSRCQDPASGER*LLK*TDLKTGGH*Q PLQELELQGQSQ*ITGPPAPAGSLEVSSPSGAS THPLQEPRATLEVPEGWRTLLGTLSSSINHQSQK QRSHSP*PPSPVEAG*CWPSQKGSVLGVWCVSY MQFPRTQLCGGHDCWPEASGPGALWFD*VHTPL EPGWPLQTNIILGTFLPVSSHPVFSPRWFLSPHP QSQCYT*GSGAQNLTASPPFCVCRGDRGNHLRK DTKVEVKRKTCWL*AWWLMPIIPALWEAGVGGS PEASRSTPAWATQQDTASTEKF*N*LGVVVCTCR PSCSGG*SRRIT*A*VQHCSELWWHHCTPAWVT EQDPVSKINFKKT

Frame 2

CTGHGSAAIQPGRSRSCEPLPRGRGAHSYGLEA PESSGDPVAAAATTAAALASARRRGASRTYPWA ASHPALGPGWTTLAHRQPGGAGLEARHGAGGPG G*RPGAPA*AGEEPQAAGPRIHRNPLRPRWAASG AGPQPHGSLPLPRASKGLPRLLGSPLHLLWDEW PDHPQQECQLLSASLATPGLQGLLNPRDLSDGA AAHLERNLWPQGSWEQSGHDQPSWWSPEQGQARS AQDPEVPGTVHCGRPHPVLDSAPKLEPHQTASP GSRQLRGPASQDSGHSGGADRPGGVDRAGPQPR HAGRQRHALGLPAVAPGAVGAAAPRLRAAAHGPR LPGRHSGPGARRGHVPRRELGRREHGPLGAPHR RRSHHGP*DRPQPRPQPRPRRLLRGGCGRVRRL RHGCGHRAPVSARVQRLQPPPAARLLPQGGRRLP LQCPGPRTPGAAGALRERLRGSGRGV*LRPWPG VPRPLLLCSQLLAAPGGPVRPRGLLRALPAEAG WSAVPPGHG*L*PP*VLHGHLLPLSPRRLPTGRL TLCQGQWLLLGWRMSHAGAAVPAALGAWLPPSS RGLFPGGELCGRCSWKLRPGQRGPLPALCREGC PVWEAAVPGWKAQPARTAHGASGLYRSPRWPGSD LSGSLGTPQCPAGPAWPGPGRARHPVWT*NGLQ *QP*LPLCSRLGSTLL*QARLWWQHGQWPCAG* KP*HLPAGHAPQRPAASAPRGRPGLVLLPTPRSP SAAMQLGLQKGPCVQWPQRWPTQGPPPGRRSPH GVGPHSHWTALAPGP*ELS*AQQPP*EASASSL A*PPSRSSPDAKILPLVRGSS*NEQI*RQVATDS HSRNLNCRGRASESPDLQHLQAAWKFLPRVELR PTHSRNPEPH*KFLRAGEHCWAHSPAQ*TISPR SKGHTAPDLPHQWRLGSAGHPKRALSWESGVSPT CNFHGPSSVEGMTAGQKLVVLGPYGSTESTLPW SLAGLCKQT*FWGPSFLFLPTLSSPLGGS*APT PNPSATPEVLELRI*QPLPHSVCVGGTEGTI*EK IPK*KSKERHVGYRRGGSCL*SQHFGKPG*EDH QRPAGPHQPGQHSKTPHLQKNFKISWAWWCVPV GLAAQEAEAGGSLEPEFNTAVSYGGTTALQPG*Q SKTLSLK*ILKRH

Sequence NM_025220

GCTGCACCGGGCACGGGTCGGCCGCAATCCAGCCTGGGCGGAGCCGGAGTTGCGAGCCGCTGCCTAGAGGCCGAGGAGCTCACAGCTATGGGCTGGAGGC CCCGGAGAGCTCGGGGGACCCCGTTGCTGCTGCTGCTACTACTGCTGCTGCTCTGGCCAGTGCCAGGCGCCGGGGTGCTTCAAGGACATATCCCTGGGCA GCCAGTCACCCCGCACTGGGTCCTGGATGGACAACCCTGGCGCACCGTCAGCCTGGAGGAGCCGGTCTCGAAGCCAGACATGGGGCTGGTGGCCCTGGAG GCTGAAGGCCAGGAGCTCCTGCTTGAGCTGGAGAAGAACCACAGGCTGCTGGCCCCAGGATACATAGAAACCCACTACGGCCCAGATGGGCAGCCAGTGG TGCTGGCCCCCAACCACACGGATCATTGCCACTACCAAGGGCGAGTAAGGGGCTTCCCCGACTCCTGGGTAGTCCTCTGCACCTGCTCTGGGATGAGTGG CCTGATCACCCTCAGCAGGAATGCCAGCTATTATCTGCGTCCCTGGCCACCCCGGGGCTCCAAGGACTTCTCAACCCACGAGATCTTTCGGATGGAGCAG CTGCTCACCTGGAAAGGAACCTGTGGCCACAGGGATCCTGGGAACAAAGCGGGCATGACCAGCCTTCCTGGTGGTCCCCAGAGCAGGGGCAGGCGAGAAG CGCGCAGGACCCGGAAGTACCTGGAACTGTACATTGTGGCAGACCACACCCTGTTCTTGACTCGGCACCGAAACTTGAACCACACCAAACAGCGTCTCCT GGAAGTCGCCAACTACGTGGACCAGCTTCTCAGGACTCTGGACATTCAGGTGGCGCTGACCGGCCTGGAGGTGTGGACCGAGCGGGACCGCAGCCGCGTC ACGCAGGACGCCAACGCCACGCTCTGGGCCTTCCTGCAGTGGCGCCGGGGGCTGTGGGCGCAGCGGCCCCACGACTCCGCGCAGCTGCTCACGGGCCGCG CCTTCCAGGGCGCCACAGTGGGCCTGGCGCCCGTCGAGGGCATGTGCCGCGCCGAGAGCTCGGGAGGCGTGAGCACGGACCACTCGGAGCTCCCCATCGG CGCCGCAGCCACCATGGCCCATGAGATCGGCCACAGCCTCGGCCTCAGCCACGACCCCGACGGCTGCTGCGTGGAGGCTGCGGCCGAGTCCGGAGGCTGC GTCATGGCTGCGGCCACCGGGCACCCGTTTCCGCGCGTGTTCAGCGCCTGCAGCCGCCGCCAGCTGCGCGCCTTCTTCCGCAAGGGGGGCGGCGCTTGCC TCTCCAATGCCCCGGACCCCGGACTCCCGGTGCCGCCGGCGCTCTGCGGGAACGGCTTCGTGGAAGCGGGCGAGGAGTGTGACTGCGGCCCTGGCCAGGA GTGCCGCGACCTCTGCTGCTTTGCTCACAACTGCTCGCTGCGCCCGGGGGCCCAGTGCGCCCACGGGGACTGCTGCGTGCGCTGCCTGCTGAAGCCGGCT GGAGCGCTGTGCCGCCAGGCCATGGGTGACTGTGACCTCCCTGAGTTTTGCACGGGCACCTCCTCCCACTGTCCCCCAGACGTTTACCTACTGGACGGCT CACCCTGTGCCAGGGGCAGTGGCTACTGCTGGGATGGCGCATGTCCCACGCTGGAGCAGCAGTGCCAGCAGCTCTGGGGGCCTGGCTCCCACCCAGCTCC CGAGGCCTGTTTCCAGGTGGTGAACTCTGCGGGAGATGCTCATGGAAACTGCGGCCAGGACAGCGAGGGCCACTTCCTGCCCTGTGCAGGGAGGGATGCC CTGTGTGGGAAGCTGCAGTGCCAGGGTGGAAAGCCCAGCCTGCTCGCACCGCACATGGTGCCAGTGGACTCTACCGTTCACCTAGATGGCCAGGAAGTGA CTTGTCGGGGAGCCTTGGCACTCCCCAGTGCCCAGCTGGACCTGCTTGGCCTGGGCCTGGTAGAGCCAGGCACCCAGTGTGGACCTAGAATGGTGTGCCA GAGCAGGCGCTGCAGGAAGAATGCCTTCCAGGAGCTTCAGCGCTGCCTGACTGCCTGCCACAGCCACGGGGTTTGCAATAGCAACCATAACTGCCACTGT GCTCCAGGCTGGGCTCCACCCTTCTGTGACAAGCCAGGCTTTGGTGGCAGCATGGACAGTGGCCCTGTGCAGGCTGAAAACCATGACACCTTCCTGCTGG CCATGCTCCTCAGCGTCCTGCTGCCTCTGCTCCCAGGGGCCGGCCTGGCCTGGTGTTGCTACCGACTCCCAGGAGCCCATCTGCAGCGATGCAGCTGGGG CTGCAGAAGGGACCCTGCGTGCAGTGGCCCCAAAGATGGCCCACACAGGGACCACCCCCTGGGCGGCGTTCACCCCATGGAGTTGGGCCCCACAGCCACT GGACAGCCCTGGCCCCTGGACCCTGAGAACTCTCATGAGCCCAGCAGCCACCCTGAGAAGCCTCTGCCAGCAGTCTCGCCTGACCCCCAAGCAGATCAAG TCCAGATGCCAAGATCCTGCCTCTGGTGAGAGGTAGCTCCTAAAATGAACAGATTTAAAGACAGGTGGCCACTGACAGCCACTCCAGGAACTTGAACTGC AGGGGCAGAGCCAGTGAATCACCGGACCTCCAGCACCTGCAGGCAGCTTGGAAGTTTCTTCCCCGAGTGGAGCTTCGACCCACCCACTCCAGGAACCCAG AGCCACATTAGAAGTTCCTGAGGGCTGGAGAACACTGCTGGGCACACTCTCCAGCTCAATAAACCATCAGTCCCAGAAGCAAAGGTCACACAGCCCCTGA CCTCCCTCACCAGTGGAGGCTGGGTAGTGCTGGCCATCCCAAAAGGGCTCTGTCCTGGGAGTCTGGTGTGTCTCCTACATGCAATTTCCACGGACCCAGC TCTGTGGAGGGCATGACTGCTGGCCAGAAGCTAGTGGTCCTGGGGCCCTATGGTTCGACTGAGTCCACACTCCCCTGGAGCCTGGCTGGCCTCTGCAAAC AAACATAATTTTGGGGACCTTCCTTCCTGTTTCTTCCCACCCTGTCTTCTCCCCTAGGTGGTTCCTGAGCCCCCACCCCCAATCCCAGTGCTACACCTGA GGTTCTGGAGCTCAGAATCTGACAGCCTCTCCCCCATTCTGTGTGTGTCGGGGGGACAGAGGGAACCATTTAAGAAAAGATACCAAAGTAGAAGTCAAAA GAAAGACATGTTGGCTATAGGCGTGGTGGCTCATGCCTATAATCCCAGCACTTTGGGAAGCCGGGGTAGGAGGATCACCAGAGGCCAGCAGGTCCACACC AGCCTGGGCAACACAGCAAGACACCGCATCTACAGAAAAATTTTAAAATTAGCTGGGCGTGGTGGTGTGTACCTGTAGGCCTAGCTGCTCAGGAGGCTGA AGCAGGAGGATCACTTGAGCCTGAGTTCAACACTGCAGTGAGCTATGGTGGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGTCTCTAAAA TAAATTTTAAAAAGACATA

refseq_ADAM33.F1 (forward primer)
refseq_ADAM33.R1 (reverse primer)
Single exon skipping

Frame 0

AAPGTGRPQSSLGGAGVASRCLEAEELTAMGWR PRRARGTPLLLLLLLLLLWPVPGAGVLQGHIPGQ PVTPHWVLDGQPWRTVSLEEPVSKPDMGLVALE AEGQELLLELEKNHRLLAPGYIETHYGPDGQPV VLAPNHTDHCHYQGRVRGFPDSWVVLCTCSGMSG LITLSRNASYYLRPWPPRGSKDFSTHEIFRMEQ LLTWKGTCGHRDPGNKAGMTSLPGGPQSRGRRE ARRTRKYLELYIVADHTLFLTRHRNLNHTKQRLL EVANYVDQLLRTLDIQVALTGLEVWTERDRSRV TQDANATLWAFLQWRRGLWAQRPHDSAQLLTGR AFQGATVGLAPVEGMCRAESSGGVSTDHSELPIG AAATMAHEIGHSLGLSHDPDGCCVEAAAESGGC VMAAATGHPFPRVFSACSRRQLRAFFRKGGGAC LSNAPDPGLPVPPALCGNGFVEAGEECDCGPGQE CRDLCCFAHNCSLRPGAQCAHGDCCVRCLLKPA GALCRQAMGDCDLPEFCTGTSSHCPPDVYLLDG SPCARGSGYCWDGACPTLEQQCQQLWGPGSHPAP EACFQVVNSAGDAHGNCGQDSEGHFLPCAGRDA LCGKLQCQGGKPSLLAPHMVPVDSTVHLDGQEV TCRGALALPSAQLDLLGLGLVEPGTQCGPRMVCQ SRRCRKNAFQELQRCLTACHSHGVCNSNHNCHC APGWAPPFCDKPGFGGSMDSGPVQAENHDTFLL AMLLSVLLPLLPGAGLAWCCYRLPGAHLQRCSWG CRRDPACSGPKDGPHRDHPLGGVHPMELGPTAT GQPWPLDPENSHEPSSHPEKPLPAVSPDPQADQ VQMPRSCLW*EVAPKMNRFKDRWPLTATPGT*TA GAEPVNHRTSSTCRQLGSFFPEWSFDPPTPGTQ SHIRSS*GLENTAGHTLQLNKPSVPEAKVTQPL TSLTSGGWVVLAIPKGLCPGSLVCLLHAISTDPA LWRA*LLARS*WSWGPMVRLSPHSPGAWLASAN KHNFGDLPSCFFPPCLLP*VVPEPPPPIPVLHL RFWSSESDSLSPILCVSGGQREPFKKRYQSRSQK KDMLAIGVVAHAYNPSTLGSRGRRITRGQQVHT SLGNTARHRIYRKILKLAGRGGVYL*A*LLRRL KQEDHLSLSSTLQ*AMVAPLHSSLGDRARPCL*N KF*KDI

Frame 1

LHRARVGRNPAWAEPELRAAA*RPRSSQLWAGG PGELGGPRCCCCYYCCCSGQCQAPGCFKDISLG SQSPRTGSWMDNPGAPSAWRSRSRSQTWGWWPWR LKARSSCLSWRRTTGCWPQDT*KPTTAQMGSQW CWPPTTRIIATTKGE*GASPTPG*SSAPALG*V A*SPSAGMPAIICVPGHPGAPRTSQPTRSFGWSS CSPGKEPVATGILGTKRA*PAFLVVPRAGAGEK RAGPGSTWNCTLWQTTPCS*LGTET*TTPNSVS WKSPTTWTSFSGLWTFRWR*PAWRCGPSGTAAAS RRTPTPRSGPSCSGAGGCGRSGPTTPRSCSRAA PSRAPQWAWRPSRACAAPRAREA*ARTTRSSPS APQPPWPMRSATASASATTPTAAAWRLRPSPEAA SWLRPPGTRFRACSAPAAAASCAPSSARGAALA SPMPRTPDSRCRRRSAGTASWKRARSVTAALAR SAATSAALLTTARCARGPSAPTGTAACAAC*SRL ERCAARPWVTVTSLSFARAPPPTVPQTFTYWTA HPVPGAVATAGMAHVPRWSSSASSSGGLAPTQL PRPVSRW*TLREMLMETAARTARATSCPVQGGMP CVGSCSARVESPACSHRTWCQWTLPFT*MARK* LVGEPWHSPVPSWTCLAWAW*SQAPSVDLEWCA RAGAAGRMPSRSFSAA*LPATATGFAIATITATV LQAGLHPSVTSQALVAAWTVALCRLKTMTPSCW PCSSASCCLCSQGPAWPGVATDSQEPICSDAAG AAEGTLRAVAPKMAHTGTTPWAAFTPWSWAPQPL DSPGPWTLRTLMSPAATLRSLCQQSRLTPKQIK SRCQDPASGER*LLK*TDLKTGGH*QPLQELEL QGQSQ*ITGPPAPAGSLEVSSPSGASTHPLQEPR ATLEVPEGWRTLLGTLSSSINHQSQKQRSHSP* PPSPVEAG*CWPSQKGSVLGVWCVSYMQFPRTQ LCGGHDCWPEASGPGALWFD*VHTPLEPGWPLQT NIILGTFLPVSSHPVFSPRWFLSPHPQSQCYT* GSGAQNLTASPPFCVCRGDRGNHLRKDTKVEVK RKTCWL*AWWLMPIIPALWEAGVGGSPEASRSTP AWATQQDTASTEKF*N*LGVVVCTCRPSCSGG* SRRIT*A*VQHCSELWWHHCTPAWVTEQDPVSK INFKKT

Frame 2

CTGHGSAAIQPGRSRSCEPLPRGRGAHSYGLEA PESSGDPVAAAATTAAALASARRRGASRTYPWA ASHPALGPGWTTLAHRQPGGAGLEARHGAGGPG G*RPGAPA*AGEEPQAAGPRIHRNPLRPRWAASG AGPQPHGSLPLPRASKGLPRLLGSPLHLLWDEW PDHPQQECQLLSASLATPGLQGLLNPRDLSDGA AAHLERNLWPQGSWEQSGHDQPSWWSPEQGQARS AQDPEVPGTVHCGRPHPVLDSAPKLEPHQTASP GSRQLRGPASQDSGHSGGADRPGGVDRAGPQPR HAGRQRHALGLPAVAPGAVGAAAPRLRAAAHGPR LPGRHSGPGARRGHVPRRELGRREHGPLGAPHR RRSHHGP*DRPQPRPQPRPRRLLRGGCGRVRRL RHGCGHRAPVSARVQRLQPPPAARLLPQGGRRLP LQCPGPRTPGAAGALRERLRGSGRGV*LRPWPG VPRPLLLCSQLLAAPGGPVRPRGLLRALPAEAG WSAVPPGHG*L*PP*VLHGHLLPLSPRRLPTGRL TLCQGQWLLLGWRMSHAGAAVPAALGAWLPPSS RGLFPGGELCGRCSWKLRPGQRGPLPALCREGC PVWEAAVPGWKAQPARTAHGASGLYRSPRWPGSD LSGSLGTPQCPAGPAWPGPGRARHPVWT*NGVP EQALQEECLPGASALPDCLPQPRGLQ*QP*LPL CSRLGSTLL*QARLWWQHGQWPCAG*KP*HLPAG HAPQRPAASAPRGRPGLVLLPTPRSPSAAMQLG LQKGPCVQWPQRWPTQGPPPGRRSPHGVGPHSH WTALAPGP*ELS*AQQPP*EASASSLA*PPSRSS PDAKILPLVRGSS*NEQI*RQVATDSHSRNLNC RGRASESPDLQHLQAAWKFLPRVELRPTHSRNP EPH*KFLRAGEHCWAHSPAQ*TISPRSKGHTAPD LPHQWRLGSAGHPKRALSWESGVSPTCNFHGPS SVEGMTAGQKLVVLGPYGSTESTLPWSLAGLCK QT*FWGPSFLFLPTLSSPLGGS*APTPNPSATPE VLELRI*QPLPHSVCVGGTEGTI*EKIPK*KSK ERHVGYRRGGSCL*SQHFGKPG*EDHQRPAGPH QPGQHSKTPHLQKNFKISWAWWCVPVGLAAQEAE AGGSLEPEFNTAVSYGGTTALQPG*QSKTLSLK *ILKRH