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Sequences

Sequence NM_014263

GGCGGATTGTCTGTCGTTGCAGTAGCTGTAGGAAGGGGAGGCCATTTTCCGTTTCTGGGAGGAGTGAGGGGCAACGGGTCGGAGAAAAAGGAAAAAAGAA
GGGCTCAGCGCCTCCCCGCCGGGCCGTGGACAGAGGGGCACAGTTTCGGCAGGCGGGTGAGGTCGCTGAGGGCCCGCCGGAGATGTTTTCCTTGTCGAGC
ACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATCAATGCCTTCCATACACCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTC
AAAACCAGCATCGAGATGTAGTTCCTGAGCATGAGGCTCCCAGCAGTGAGCCTTCACTTAACTTAAGGGACCTTGGATTATCTGAACTAAAAATTGGACA
GATTGATCAGCTGGTAGAAAATCTACTTCCTGGATTTTGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTCTCTGCACAATCCTTCTTT
GAAAATAAATATGGTAACTTAGATATATTTAGTACATTACGTTCCTCTTGCTTGTATCGACATCATTCAAGAGCTCTTCAAAGCATTTGTTCAGATCTTC
AGTACTGGCCAGTTTTCATACAGTCTCGGGGTTTTAAAACTTTGAAATCAAGGACACGACGTCTCCAGTCTACCTCCGAGAGATTAGCTGAAACACAGAA
TATAGCGCCATCATTCGTGAAGGGGTTTCTTTTGCGGGACAGAGGATCAGATGTTGAGAGTTTGGACAAACTCATGAAAACCAAAAATATACCTGAAGCT
CACCAAGATGCATTTAAAACTGGTTTTGCGGAAGGTTTTCTGAAAGCTCAAGCACTCACACAAAAAACCAATGATTCCCTAAGGCGAACCCGTCTGATTC
TCTTCGTTCTGCTGCTATTCGGCATTTATGGACTTCTAAAAAACCCATTTTTATCTGTCCGCTTCCGGACAACAACAGGGCTTGATTCTGCAGTAGATCC
TGTCCAGATGAAAAATGTCACCTTTGAACATGTTAAAGGGGTGGAGGAAGCTAAACAAGAATTACAGGAAGTTGTTGAATTCTTGAAAAATCCACAAAAA
TTTACTATTCTTGGAGGTAAACTTCCAAAAGGAATTCTTTTAGTTGGACCCCCAGGGACTGGAAAGACACTTCTTGCCCGAGCTGTGGCGGGAGAAGCTG
ATGTTCCTTTTTATTATGCTTCTGGATCCGAATTTGATGAGATGTTTGTGGGTGTGGGAGCCAGCCGTATCAGAAATCTTTTTAGGGAAGCAAAGGCGAA
TGCTCCTTGTGTTATATTTATTGATGAATTAGATTCTGTTGGTGGGAAGAGAATTGAATCTCCAATGCATCCATATTCAAGGCAGACCATAAATCAACTT
CTTGCTGAAATGGATGGTTTTAAACCCAATGAAGGAGTTATCATAATAGGAGCCACAAACTTCCCAGAGGCATTAGATAATGCCTTAATACGTCCTGGTC
GTTTTGACATGCAAGTTACAGTTCCAAGGCCAGATGTAAAAGGTCGAACAGAAATTTTGAAATGGTATCTCAATAAAATAAAGTTTGATCAATCCGTTGA
TCCAGAAATTATAGCTCGAGGTACTGTTGGCTTTTCCGGAGCAGAGTTGGAGAATCTTGTGAACCAGGCTGCATTAAAAGCAGCTGTTGATGGAAAAGAA
ATGGTTACCATGAAGGAGCTGGAGTTTTCCAAAGACAAAATTCTAATGGGGCCTGAAAGAAGAAGTGTGGAAATTGATAACAAAAACAAAACCATCACAG
CATATCATGAATCTGGTCATGCCATTATTGCATATTACACAAAAGATGCAATGCCTATCAACAAAGCTACAATCATGCCACGGGGGCCAACACTTGGACA
TGTGTCCCTGTTACCTGAGAATGACAGATGGAATGAAACTAGAGCCCAGCTGCTTGCACAAATGGATGTTAGTATGGGAGGAAGAGTGGCAGAGGAGCTT
ATATTTGGAACCGACCATATTACAACAGGTGCTTCCAGTGATTTTGATAATGCCACTAAAATAGCAAAGCGGATGGTTACCAAATTTGGAATGAGTGAAA
AGCTTGGAGTTATGACCTACAGTGATACAGGGAAACTAAGTCCAGAAACCCAATCTGCCATCGAACAAGAAATAAGAATCCTTCTAAGGGACTCATATGA
ACGAGCAAAACATATCTTGAAAACTCATGCAAAGGAGCATAAGAATCTCGCAGAAGCTTTATTGACCTATGAGACTTTGGATGCCAAAGAGATTCAAATT
GTTCTTGAGGGGAAAAAGTTGGAAGTGAGATGATAACTCTCTTGATATGGATGCTTGCTGGTTTTATTGCAAGAATACAAGTAGCATTGCAGTAGTCTAC
TTTTACAACGCTTTCCCCTCATTCTTGATGTGGTGTAATTGAAGGGTGTGAAATGCTTTGTCAATCATTTGTCACATTTATCCAGTTTGGGTTATTCTCA
TTATGACACCTATTGCAAATTAGCATCCCATGGCAAATATATTTTGAAAAAATAAAGAACTATCAGGATTGAAAACAGCTCTTTTGAGGAATGTCAATTA
GTTATTAAGTTGAAAGTAATTAATGATTTTATGTTTGGTTACTCTACTAGATTTGATAAAAATTGTGCCTTTAGCCTTCTATATACATCAGTGGAAACTT
AAGATGCAGTAATTATGTTCCAGATTGACCATGAATAAAATATTTTTTAATCTAAATGTAGAGAAGTTGGGATTAAAAGCAGTCTCGGAAACACAGAGCC
AGGAATATAGCCTTTTGGCATGGTGCCATGGCTCACATCTGTAATCCCAGCACTTTTGGAGGCTGAGGCGGGTGGATTGCTTGAGGCCAGGAGTTCGAGA
CCAGCCTGGCCAACGTGGTGAAACGCTGTCTCTACTAAAATACAAAAAAATAGGGCTGGGCGCGGTTGCTCACGCCTGTAATCCCAGCACTTTTCAGAGG
CCAAGGCGGGCAAATCACCTGAGGTCAAGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAACATGCAAAAATTACCTGGGCATG
GTGGCAGGTGCTTATAATCCCAGCTACTCTGGGGGCCAAGGCAGGAGAATTGCTTGAGCCTGGGAGATGGAGGTTGCAGTGAGCTGAGATCATGCCACTG
CACTCCAGCCTGGGCAACAGAGCAAGACTCTGCCTCAAAAAAAAATTAAAATAAATTTAAATACAAAAAAAAATAGCCAGGTGTGGGGTGCATGCCTGGA
ATCCCAGCTACTTGAGAGGCTGAGGCACGAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCACAGGAGCCACTGCACTCCAGCCTG
GGTGACAGAGTGAGACTCTGTCTCAAAAAAAAATTAAATAAATTATTATAACCTTTCAGAAATGCTGTGTGCATTTTCATGTTCTTTTTTTTAGCATTAC
TGTCACTCTCCCTAATGAAATGTACTTCAGAGAAGCAGTATTTTGTTAAATAAATACATAACCTCATTCTGAATAATGTCCCTCATTTTGACTATAACTG
TGCTTGGTTTCAAAAGCAAAATTAAACAAAAATCTCAGTCCCCTCCGAAGTGAACTTTGTGTTACCCTGCGTCAGAAATGCCAAGTTGTGTTTACTTTTC
ATTCAGATTTTGTGAATATGAACATGCTGTTATAGGATCTACAGATGAATATTTAACTCAATAGAAAAATTATTTTAGAACACATTGTATTGGTATTACA
ACCAGATTATATTCTTGACGTTGACTTCATTAAAATTATCTACAATTTCCTAATAA
  • refseq_YME1L1.F2 (forward primer)
  • refseq_YME1L1.R2 (reverse primer)
  • Single exon skipping

Frame 0

GGLSVVAVAVGRGGHFPFLGGVRGNGSEKKEKR
RAQRLPAGPWTEGHSFGRRVRSLRARRRCFPCRA
RCNPRLQFL*VISSMPSIHQKTLLFLSVECQFL
KTSIEM*FLSMRLPAVSLHLT*GTLDYLN*KLD
RLISW*KIYFLDFVKAKTFLPIGIHPMSLHNPSL
KINMVT*IYLVHYVPLACIDIIQELFKAFVQIF
STGQFSYSLGVLKL*NQGHDVSSLPPRD*LKHR
I*RHHS*RGFFCGTEDQMLRVWTNS*KPKIYLKL
TKMHLKLVLRKVF*KLKHSHKKPMIP*GEPV*F
SSFCCYSAFMDF*KTHFYLSASGQQQGLILQ*I
LSR*KMSPLNMLKGWRKLNKNYRKLLNS*KIHKN
LLFLEVNFQKEFF*LDPQGLERHFLPELWREKL
MFLFIMLLDPNLMRCLWVWEPAVSEIFLGKQRR
MLLVLYLLMN*ILLVGRELNLQCIHIQGRP*INF
LLKWMVLNPMKELS**EPQTSQRH*IMP*YVLV
VLTCKLQFQGQM*KVEQKF*NGISIK*SLINPL
IQKL*LEVLLAFPEQSWRIL*TRLH*KQLLMEKK
WLP*RSWSFPKTKF*WGLKEEVWKLITKTKPSQ
HIMNLVMPLLHITQKMQCLSTKLQSCHGGQHLD
MCPCYLRMTDGMKLEPSCLHKWMLVWEEEWQRSL
YLEPTILQQVLPVILIMPLK*QSGWLPNLE*VK
SLEL*PTVIQGN*VQKPNLPSNKK*ESF*GTHM
NEQNIS*KLMQRSIRISQKLY*PMRLWMPKRFKL
FLRGKSWK*DDNSLDMDACWFYCKNTSSIAVVY
FYNAFPSFLMWCN*RV*NALSIICHIYPVWVIL
IMTPIAN*HPMANIF*KNKELSGLKTALLRNVN*
LLS*K*LMILCLVTLLDLIKIVPLAFYIHQWKL
KMQ*LCSRLTMNKIFFNLNVEKLGLKAVSETQS
QEYSLLAWCHGSHL*SQHFWRLRRVDCLRPGVRD
QPGQRGETLSLLKYKKIGLGAVAHACNPSTFQR
PRRANHLRSRV*DQPGQHGETPSLLNMQKLPGH
GGRCL*SQLLWGPRQENCLSLGDGGCSELRSCHC
TPAWATEQDSASKKN*NKFKYKKK*PGVGCMPG
IPAT*EAEARELLEPRRWRLQ*AKITGATALQP
G*QSETLSQKKIK*IIITFQKCCVHFHVLFFSIT
VTLPNEMYFREAVFC*INT*PHSE*CPSF*L*L
CLVSKAKLNKNLSPLRSELCVTLRQKCQVVFTF
HSDFVNMNMLL*DLQMNI*LNRKIILEHIVLVLQ
PDYILDVDFIKIIYNFLI

Frame 1

ADCLSLQ*L*EGEAIFRFWEE*GATGRRKRKKE
GLSASPPGRGQRGTVSAGG*GR*GPAGDVFLVE
HGATPGYSSSESSHQCLPYTKKHFCFSQWSVSFS
KPASRCSS*A*GSQQ*AFT*LKGPWII*TKNWT
D*SAGRKSTSWIL*RQKHFFPLAYIPCLCTILL
*K*IW*LRYI*YITFLLLVSTSFKSSSKHLFRSS
VLASFHTVSGF*NFEIKDTTSPVYLREIS*NTE
YSAIIREGVSFAGQRIRC*EFGQTHENQKYT*S
SPRCI*NWFCGRFSESSSTHTKNQ*FPKANPSDS
LRSAAIRHLWTSKKPIFICPLPDNNRA*FCSRS
CPDEKCHL*TC*RGGGS*TRITGSC*ILEKSTK
IYYSWR*TSKRNSFSWTPRDWKDTSCPSCGGRS*
CSFLLCFWIRI**DVCGCGSQPYQKSF*GSKGE
CSLCYIY**IRFCWWEEN*ISNASIFKADHKST
SC*NGWF*TQ*RSYHNRSHKLPRGIR*CLNTSWS
F*HASYSSKARCKRSNRNFEMVSQ*NKV*SIR*
SRNYSSRYCWLFRSRVGESCEPGCIKSSC*WKR
NGYHEGAGVFQRQNSNGA*KKKCGN**QKQNHHS
IS*IWSCHYCILHKRCNAYQQSYNHATGANTWT
CVPVT*E*QME*N*SPAACTNGC*YGRKSGRGA
YIWNRPYYNRCFQ*F**CH*NSKADGYQIWNE*K
AWSYDLQ*YRETKSRNPICHRTRNKNPSKGLI*
TSKTYLENSCKGA*ESRRSFIDL*DFGCQRDSN
CS*GEKVGSEMITLLIWMLAGFIARIQVALQ*ST
FTTLSPHS*CGVIEGCEMLCQSFVTFIQFGLFS
L*HLLQISIPWQIYFEKIKNYQD*KQLF*GMSI
SY*VESN**FYVWLLY*I**KLCL*PSIYISGNL
RCSNYVPD*P*IKYFLI*M*RSWD*KQSRKHRA
RNIAFWHGAMAHICNPSTFGG*GGWIA*GQEFE
TSLANVVKRCLY*NTKK*GWARLLTPVIPALFRG
QGGQIT*GQEFETSLANMVKPHLY*TCKNYLGM
VAGAYNPSYSGGQGRRIA*AWEMEVAVS*DHAT
ALQPGQQSKTLPQKKIKINLNTKKNSQVWGACLE
SQLLERLRHENCLNPGGGGCSEPRSQEPLHSSL
GDRVRLCLKKKLNKLL*PFRNAVCIFMFFFLAL
LSLSLMKCTSEKQYFVK*IHNLILNNVPHFDYNC
AWFQKQN*TKISVPSEVNFVLPCVRNAKLCLLF
IQIL*I*TCCYRIYR*IFNSIEKLF*NTLYWYY
NQIIFLTLTSLKLSTIS**

Frame 2

RIVCRCSSCRKGRPFSVSGRSEGQRVGEKGKKK
GSAPPRRAVDRGAQFRQAGEVAEGPPEMFSLSS
TVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVS
QNQHRDVVPEHEAPSSEPSLNLRDLGLSELKIGQ
IDQLVENLLPGFCKGKNISSHWHTSHVSAQSFF
ENKYGNLDIFSTLRSSCLYRHHSRALQSICSDL
QYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQN
IAPSFVKGFLLRDRGSDVESLDKLMKTKNIPEA
HQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLI
LFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDP
VQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQK
FTILGGKLPKGILLVGPPGTGKTLLARAVAGEA
DVPFYYASGSEFDEMFVGVGASRIRNLFREAKAN
APCVIFIDELDSVGGKRIESPMHPYSRQTINQL
LAEMDGFKPNEGVIIIGATNFPEALDNALIRPG
RFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVD
PEIIARGTVGFSGAELENLVNQAALKAAVDGKE
MVTMKELEFSKDKILMGPERRSVEIDNKNKTIT
AYHESGHAIIAYYTKDAMPINKATIMPRGPTLGH
VSLLPENDRWNETRAQLLAQMDVSMGGRVAEEL
IFGTDHITTGASSDFDNATKIAKRMVTKFGMSE
KLGVMTYSDTGKLSPETQSAIEQEIRILLRDSYE
RAKHILKTHAKEHKNLAEALLTYETLDAKEIQI
VLEGKKLEVR**LS*YGCLLVLLQEYK*HCSSL
LLQRFPLILDVV*LKGVKCFVNHLSHLSSLGYSH
YDTYCKLASHGKYILKK*RTIRIENSSFEECQL
VIKLKVINDFMFGYSTRFDKNCAFSLLYTSVET
*DAVIMFQIDHE*NIF*SKCREVGIKSSLGNTEP
GI*PFGMVPWLTSVIPALLEAEAGGLLEARSSR
PAWPTW*NAVSTKIQKNRAGRGCSRL*SQHFSE
AKAGKSPEVKSLRPAWPTW*NPISTKHAKITWAW
WQVLIIPATLGAKAGELLEPGRWRLQ*AEIMPL
HSSLGNRARLCLKKKLK*I*IQKKIARCGVHAW
NPSYLRG*GTRIA*TQEVEVAVSQDHRSHCTPAW
VTE*DSVSKKN*INYYNLSEMLCAFSCSFF*HY
CHSP**NVLQRSSILLNKYITSF*IMSLILTIT
VLGFKSKIKQKSQSPPK*TLCYPASEMPSCVYFS
FRFCEYEHAVIGSTDEYLTQ*KNYFRTHCIGIT
TRLYS*R*LH*NYLQFPN

Sequence NM_139313

GGCGGATTGTCTGTCGTTGCAGTAGCTGTAGGAAGGGGAGGCCATTTTCCGTTTCTGGGAGGAGTGAGGGGCAACGGGTCGGAGAAAAAGGAAAAAAGAA
GGGCTCAGCGCCTCCCCGCCGGGCCGTGGACAGAGGGGCACAGTTTCGGCAGGCGGGTGAGGTCGCTGAGGGCCCGCCGGAGATGTTTTCCTTGTCGAGC
ACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATCAATGCCTTCCATACACCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTC
AAAACCAGCATCGAGATGTAGTTCCTGAGCATGAGGCTCCCAGCAGTGAGTGTATGTTCAGTGACTTCCTGACGAAGCTTAACATTGTTTCAATTGGCAA
AGGAAAAATATTCGAAGGGTACAGATCCATGTTCATGGAGCCAGCAAAAAGGATGAAGAAGAGCTTGGACACAACCGATAACTGGCACATCCGTCCAGAA
CCCTTCTCCCTCTCAATCCCTCCTTCACTTAACTTAAGGGACCTTGGATTATCTGAACTAAAAATTGGACAGATTGATCAGCTGGTAGAAAATCTACTTC
CTGGATTTTGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTCTCTGCACAATCCTTCTTTGAAAATAAATATGGTAACTTAGATATATT
TAGTACATTACGTTCCTCTTGCTTGTATCGACATCATTCAAGAGCTCTTCAAAGCATTTGTTCAGATCTTCAGTACTGGCCAGTTTTCATACAGTCTCGG
GGTTTTAAAACTTTGAAATCAAGGACACGACGTCTCCAGTCTACCTCCGAGAGATTAGCTGAAACACAGAATATAGCGCCATCATTCGTGAAGGGGTTTC
TTTTGCGGGACAGAGGATCAGATGTTGAGAGTTTGGACAAACTCATGAAAACCAAAAATATACCTGAAGCTCACCAAGATGCATTTAAAACTGGTTTTGC
GGAAGGTTTTCTGAAAGCTCAAGCACTCACACAAAAAACCAATGATTCCCTAAGGCGAACCCGTCTGATTCTCTTCGTTCTGCTGCTATTCGGCATTTAT
GGACTTCTAAAAAACCCATTTTTATCTGTCCGCTTCCGGACAACAACAGGGCTTGATTCTGCAGTAGATCCTGTCCAGATGAAAAATGTCACCTTTGAAC
ATGTTAAAGGGGTGGAGGAAGCTAAACAAGAATTACAGGAAGTTGTTGAATTCTTGAAAAATCCACAAAAATTTACTATTCTTGGAGGTAAACTTCCAAA
AGGAATTCTTTTAGTTGGACCCCCAGGGACTGGAAAGACACTTCTTGCCCGAGCTGTGGCGGGAGAAGCTGATGTTCCTTTTTATTATGCTTCTGGATCC
GAATTTGATGAGATGTTTGTGGGTGTGGGAGCCAGCCGTATCAGAAATCTTTTTAGGGAAGCAAAGGCGAATGCTCCTTGTGTTATATTTATTGATGAAT
TAGATTCTGTTGGTGGGAAGAGAATTGAATCTCCAATGCATCCATATTCAAGGCAGACCATAAATCAACTTCTTGCTGAAATGGATGGTTTTAAACCCAA
TGAAGGAGTTATCATAATAGGAGCCACAAACTTCCCAGAGGCATTAGATAATGCCTTAATACGTCCTGGTCGTTTTGACATGCAAGTTACAGTTCCAAGG
CCAGATGTAAAAGGTCGAACAGAAATTTTGAAATGGTATCTCAATAAAATAAAGTTTGATCAATCCGTTGATCCAGAAATTATAGCTCGAGGTACTGTTG
GCTTTTCCGGAGCAGAGTTGGAGAATCTTGTGAACCAGGCTGCATTAAAAGCAGCTGTTGATGGAAAAGAAATGGTTACCATGAAGGAGCTGGAGTTTTC
CAAAGACAAAATTCTAATGGGGCCTGAAAGAAGAAGTGTGGAAATTGATAACAAAAACAAAACCATCACAGCATATCATGAATCTGGTCATGCCATTATT
GCATATTACACAAAAGATGCAATGCCTATCAACAAAGCTACAATCATGCCACGGGGGCCAACACTTGGACATGTGTCCCTGTTACCTGAGAATGACAGAT
GGAATGAAACTAGAGCCCAGCTGCTTGCACAAATGGATGTTAGTATGGGAGGAAGAGTGGCAGAGGAGCTTATATTTGGAACCGACCATATTACAACAGG
TGCTTCCAGTGATTTTGATAATGCCACTAAAATAGCAAAGCGGATGGTTACCAAATTTGGAATGAGTGAAAAGCTTGGAGTTATGACCTACAGTGATACA
GGGAAACTAAGTCCAGAAACCCAATCTGCCATCGAACAAGAAATAAGAATCCTTCTAAGGGACTCATATGAACGAGCAAAACATATCTTGAAAACTCATT
CTTGATGTGGTGTAATTGAAGGGTGTGAAATGCTTTGTCAATCATTTGTCACATTTATCCAGTTTGGGTTATTCTCATTATGACACCTATTGCAAATTAG
CATCCCATGGCAAATATATTTTGAAAAAATAAAGAACTATCAGGATTGAAAACAGCTCTTTTGAGGAATGTCAATTAGTTATTAAGTTGAAAGTAATTAA
TGATTTTATGTTTGGTTACTCTACTAGATTTGATAAAAATTGTGCCTTTAGCCTTCTATATACATCAGTGGAAACTTAAGATGCAGTAATTATGTTCCAG
ATTGACCATGAATAAAATATTTTTTAATCTAAATGTAGAGAAGTTGGGATTAAAAGCAGTCTCGGAAACACAGAGCCAGGAATATAGCCTTTTGGCATGG
TGCCATGGCTCACATCTGTAATCCCAGCACTTTTGGAGGCTGAGGCGGGTGGATTGCTTGAGGCCAGGAGTTCGAGACCAGCCTGGCCAACGTGGTGAAA
CGCTGTCTCTACTAAAATACAAAAAAATAGGGCTGGGCGCGGTTGCTCACGCCTGTAATCCCAGCACTTTTCAGAGGCCAAGGCGGGCAAATCACCTGAG
GTCAAGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAACATGCAAAAATTACCTGGGCATGGTGGCAGGTGCTTATAATCCCAG
CTACTCTGGGGGCCAAGGCAGGAGAATTGCTTGAGCCTGGGAGATGGAGGTTGCAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTGGGCAACAGAGC
AAGACTCTGCCTCAAAAAAAAATTAAAATAAATTTAAATACAAAAAAAAATAGCCAGGTGTGGGGTGCATGCCTGGAATCCCAGCTACTTGAGAGGCTGA
GGCACGAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCACAGGAGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTCT
CAAAAAAAAATTAAATAAATTATTATAACCTTTCAGAAATGCTGTGTGCATTTTCATGTTCTTTTTTTTAGCATTACTGTCACTCTCCCTAATGAAATGT
ACTTCAGAGAAGCAGTATTTTGTTAAATAAATACATAACCTCATTCTGAATAATGTCCCTCATTTTGACTATAACTGTGCTTGGTTTCAAAAGCAAAATT
AAACAAAAATCTCAGTCCCCTCCGAAGTGAACTTTGTGTTACCCTGCGTCAGAAATGCCAAGTTGTGTTTACTTTTCATTCAGATTTTGTGAATATGAAC
ATGCTGTTATAGGATCTACAGATGAATATTTAACTCAATAGAAAAATTATTTTAGAACACATTGTATTGGTATTACAACCAGATTATATTCTTGACGTTG
ACTTCATTAAAATTATCTACAATTTCCTAATAA
  • refseq_YME1L1.F2 (forward primer)
  • refseq_YME1L1.R2 (reverse primer)
  • Single exon skipping

Frame 0

GGLSVVAVAVGRGGHFPFLGGVRGNGSEKKEKR
RAQRLPAGPWTEGHSFGRRVRSLRARRRCFPCRA
RCNPRLQFL*VISSMPSIHQKTLLFLSVECQFL
KTSIEM*FLSMRLPAVSVCSVTS*RSLTLFQLA
KEKYSKGTDPCSWSQQKG*RRAWTQPITGTSVQN
PSPSQSLLHLT*GTLDYLN*KLDRLISW*KIYF
LDFVKAKTFLPIGIHPMSLHNPSLKINMVT*IY
LVHYVPLACIDIIQELFKAFVQIFSTGQFSYSLG
VLKL*NQGHDVSSLPPRD*LKHRI*RHHS*RGF
FCGTEDQMLRVWTNS*KPKIYLKLTKMHLKLVL
RKVF*KLKHSHKKPMIP*GEPV*FSSFCCYSAFM
DF*KTHFYLSASGQQQGLILQ*ILSR*KMSPLN
MLKGWRKLNKNYRKLLNS*KIHKNLLFLEVNFQ
KEFF*LDPQGLERHFLPELWREKLMFLFIMLLDP
NLMRCLWVWEPAVSEIFLGKQRRMLLVLYLLMN
*ILLVGRELNLQCIHIQGRP*INFLLKWMVLNP
MKELS**EPQTSQRH*IMP*YVLVVLTCKLQFQG
QM*KVEQKF*NGISIK*SLINPLIQKL*LEVLL
AFPEQSWRIL*TRLH*KQLLMEKKWLP*RSWSF
PKTKF*WGLKEEVWKLITKTKPSQHIMNLVMPLL
HITQKMQCLSTKLQSCHGGQHLDMCPCYLRMTD
GMKLEPSCLHKWMLVWEEEWQRSLYLEPTILQQ
VLPVILIMPLK*QSGWLPNLE*VKSLEL*PTVIQ
GN*VQKPNLPSNKK*ESF*GTHMNEQNIS*KLI
LDVV*LKGVKCFVNHLSHLSSLGYSHYDTYCKL
ASHGKYILKK*RTIRIENSSFEECQLVIKLKVIN
DFMFGYSTRFDKNCAFSLLYTSVET*DAVIMFQ
IDHE*NIF*SKCREVGIKSSLGNTEPGI*PFGM
VPWLTSVIPALLEAEAGGLLEARSSRPAWPTW*N
AVSTKIQKNRAGRGCSRL*SQHFSEAKAGKSPE
VKSLRPAWPTW*NPISTKHAKITWAWWQVLIIP
ATLGAKAGELLEPGRWRLQ*AEIMPLHSSLGNRA
RLCLKKKLK*I*IQKKIARCGVHAWNPSYLRG*
GTRIA*TQEVEVAVSQDHRSHCTPAWVTE*DSV
SKKN*INYYNLSEMLCAFSCSFF*HYCHSP**NV
LQRSSILLNKYITSF*IMSLILTITVLGFKSKI
KQKSQSPPK*TLCYPASEMPSCVYFSFRFCEYE
HAVIGSTDEYLTQ*KNYFRTHCIGITTRLYS*R*
LH*NYLQFPN

Frame 1

ADCLSLQ*L*EGEAIFRFWEE*GATGRRKRKKE
GLSASPPGRGQRGTVSAGG*GR*GPAGDVFLVE
HGATPGYSSSESSHQCLPYTKKHFCFSQWSVSFS
KPASRCSS*A*GSQQ*VYVQ*LPDEA*HCFNWQ
RKNIRRVQIHVHGASKKDEEELGHNR*LAHPSR
TLLPLNPSFT*LKGPWII*TKNWTD*SAGRKSTS
WIL*RQKHFFPLAYIPCLCTILL*K*IW*LRYI
*YITFLLLVSTSFKSSSKHLFRSSVLASFHTVS
GF*NFEIKDTTSPVYLREIS*NTEYSAIIREGVS
FAGQRIRC*EFGQTHENQKYT*SSPRCI*NWFC
GRFSESSSTHTKNQ*FPKANPSDSLRSAAIRHL
WTSKKPIFICPLPDNNRA*FCSRSCPDEKCHL*T
C*RGGGS*TRITGSC*ILEKSTKIYYSWR*TSK
RNSFSWTPRDWKDTSCPSCGGRS*CSFLLCFWI
RI**DVCGCGSQPYQKSF*GSKGECSLCYIY**I
RFCWWEEN*ISNASIFKADHKSTSC*NGWF*TQ
*RSYHNRSHKLPRGIR*CLNTSWSF*HASYSSK
ARCKRSNRNFEMVSQ*NKV*SIR*SRNYSSRYCW
LFRSRVGESCEPGCIKSSC*WKRNGYHEGAGVF
QRQNSNGA*KKKCGN**QKQNHHSIS*IWSCHY
CILHKRCNAYQQSYNHATGANTWTCVPVT*E*QM
E*N*SPAACTNGC*YGRKSGRGAYIWNRPYYNR
CFQ*F**CH*NSKADGYQIWNE*KAWSYDLQ*Y
RETKSRNPICHRTRNKNPSKGLI*TSKTYLENSF
LMWCN*RV*NALSIICHIYPVWVILIMTPIAN*
HPMANIF*KNKELSGLKTALLRNVN*LLS*K*L
MILCLVTLLDLIKIVPLAFYIHQWKLKMQ*LCSR
LTMNKIFFNLNVEKLGLKAVSETQSQEYSLLAW
CHGSHL*SQHFWRLRRVDCLRPGVRDQPGQRGE
TLSLLKYKKIGLGAVAHACNPSTFQRPRRANHLR
SRV*DQPGQHGETPSLLNMQKLPGHGGRCL*SQ
LLWGPRQENCLSLGDGGCSELRSCHCTPAWATE
QDSASKKN*NKFKYKKK*PGVGCMPGIPAT*EAE
ARELLEPRRWRLQ*AKITGATALQPG*QSETLS
QKKIK*IIITFQKCCVHFHVLFFSITVTLPNEM
YFREAVFC*INT*PHSE*CPSF*L*LCLVSKAKL
NKNLSPLRSELCVTLRQKCQVVFTFHSDFVNMN
MLL*DLQMNI*LNRKIILEHIVLVLQPDYILDV
DFIKIIYNFLI

Frame 2

RIVCRCSSCRKGRPFSVSGRSEGQRVGEKGKKK
GSAPPRRAVDRGAQFRQAGEVAEGPPEMFSLSS
TVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVS
QNQHRDVVPEHEAPSSECMFSDFLTKLNIVSIGK
GKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPE
PFSLSIPPSLNLRDLGLSELKIGQIDQLVENLL
PGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIF
STLRSSCLYRHHSRALQSICSDLQYWPVFIQSR
GFKTLKSRTRRLQSTSERLAETQNIAPSFVKGF
LLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFA
EGFLKAQALTQKTNDSLRRTRLILFVLLLFGIY
GLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFE
HVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPK
GILLVGPPGTGKTLLARAVAGEADVPFYYASGS
EFDEMFVGVGASRIRNLFREAKANAPCVIFIDE
LDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPN
EGVIIIGATNFPEALDNALIRPGRFDMQVTVPR
PDVKGRTEILKWYLNKIKFDQSVDPEIIARGTV
GFSGAELENLVNQAALKAAVDGKEMVTMKELEFS
KDKILMGPERRSVEIDNKNKTITAYHESGHAII
AYYTKDAMPINKATIMPRGPTLGHVSLLPENDR
WNETRAQLLAQMDVSMGGRVAEELIFGTDHITTG
ASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDT
GKLSPETQSAIEQEIRILLRDSYERAKHILKTH
S*CGVIEGCEMLCQSFVTFIQFGLFSL*HLLQIS
IPWQIYFEKIKNYQD*KQLF*GMSISY*VESN*
*FYVWLLY*I**KLCL*PSIYISGNLRCSNYVP
D*P*IKYFLI*M*RSWD*KQSRKHRARNIAFWHG
AMAHICNPSTFGG*GGWIA*GQEFETSLANVVK
RCLY*NTKK*GWARLLTPVIPALFRGQGGQIT*
GQEFETSLANMVKPHLY*TCKNYLGMVAGAYNPS
YSGGQGRRIA*AWEMEVAVS*DHATALQPGQQS
KTLPQKKIKINLNTKKNSQVWGACLESQLLERL
RHENCLNPGGGGCSEPRSQEPLHSSLGDRVRLCL
KKKLNKLL*PFRNAVCIFMFFFLALLSLSLMKC
TSEKQYFVK*IHNLILNNVPHFDYNCAWFQKQN
*TKISVPSEVNFVLPCVRNAKLCLLFIQIL*I*T
CCYRIYR*IFNSIEKLF*NTLYWYYNQIIFLTL
TSLKLSTIS**

Sequence NM_139312

GGCGGATTGTCTGTCGTTGCAGTAGCTGTAGGAAGGGGAGGCCATTTTCCGTTTCTGGGAGGAGTGAGGGGCAACGGGTCGGAGAAAAAGGAAAAAAGAA
GGGCTCAGCGCCTCCCCGCCGGGCCGTGGACAGAGGGGCACAGTTTCGGCAGGCGGGTGAGGTCGCTGAGGGCCCGCCGGAGATGTTTTCCTTGTCGAGC
ACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATCAATGCCTTCCATACACCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTC
AAAACCAGCATCGAGATGTAGTTCCTGAGCATGAGGCTCCCAGCAGTGAGTGTATGTTCAGTGACTTCCTGACGAAGCTTAACATTGTTTCAATTGGCAA
AGGAAAAATATTCGAAGGGTACAGATCCATGTTCATGGAGCCAGCAAAAAGGATGAAGAAGAGCTTGGACACAACCGATAACTGGCACATCCGTCCAGAA
CCCTTCTCCCTCTCAATCCCTCCTTCACTTAACTTAAGGGACCTTGGATTATCTGAACTAAAAATTGGACAGATTGATCAGCTGGTAGAAAATCTACTTC
CTGGATTTTGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTCTCTGCACAATCCTTCTTTGAAAATAAATATGGTAACTTAGATATATT
TAGTACATTACGTTCCTCTTGCTTGTATCGACATCATTCAAGAGCTCTTCAAAGCATTTGTTCAGATCTTCAGTACTGGCCAGTTTTCATACAGTCTCGG
GGTTTTAAAACTTTGAAATCAAGGACACGACGTCTCCAGTCTACCTCCGAGAGATTAGCTGAAACACAGAATATAGCGCCATCATTCGTGAAGGGGTTTC
TTTTGCGGGACAGAGGATCAGATGTTGAGAGTTTGGACAAACTCATGAAAACCAAAAATATACCTGAAGCTCACCAAGATGCATTTAAAACTGGTTTTGC
GGAAGGTTTTCTGAAAGCTCAAGCACTCACACAAAAAACCAATGATTCCCTAAGGCGAACCCGTCTGATTCTCTTCGTTCTGCTGCTATTCGGCATTTAT
GGACTTCTAAAAAACCCATTTTTATCTGTCCGCTTCCGGACAACAACAGGGCTTGATTCTGCAGTAGATCCTGTCCAGATGAAAAATGTCACCTTTGAAC
ATGTTAAAGGGGTGGAGGAAGCTAAACAAGAATTACAGGAAGTTGTTGAATTCTTGAAAAATCCACAAAAATTTACTATTCTTGGAGGTAAACTTCCAAA
AGGAATTCTTTTAGTTGGACCCCCAGGGACTGGAAAGACACTTCTTGCCCGAGCTGTGGCGGGAGAAGCTGATGTTCCTTTTTATTATGCTTCTGGATCC
GAATTTGATGAGATGTTTGTGGGTGTGGGAGCCAGCCGTATCAGAAATCTTTTTAGGGAAGCAAAGGCGAATGCTCCTTGTGTTATATTTATTGATGAAT
TAGATTCTGTTGGTGGGAAGAGAATTGAATCTCCAATGCATCCATATTCAAGGCAGACCATAAATCAACTTCTTGCTGAAATGGATGGTTTTAAACCCAA
TGAAGGAGTTATCATAATAGGAGCCACAAACTTCCCAGAGGCATTAGATAATGCCTTAATACGTCCTGGTCGTTTTGACATGCAAGTTACAGTTCCAAGG
CCAGATGTAAAAGGTCGAACAGAAATTTTGAAATGGTATCTCAATAAAATAAAGTTTGATCAATCCGTTGATCCAGAAATTATAGCTCGAGGTACTGTTG
GCTTTTCCGGAGCAGAGTTGGAGAATCTTGTGAACCAGGCTGCATTAAAAGCAGCTGTTGATGGAAAAGAAATGGTTACCATGAAGGAGCTGGAGTTTTC
CAAAGACAAAATTCTAATGGGGCCTGAAAGAAGAAGTGTGGAAATTGATAACAAAAACAAAACCATCACAGCATATCATGAATCTGGTCATGCCATTATT
GCATATTACACAAAAGATGCAATGCCTATCAACAAAGCTACAATCATGCCACGGGGGCCAACACTTGGACATGTGTCCCTGTTACCTGAGAATGACAGAT
GGAATGAAACTAGAGCCCAGCTGCTTGCACAAATGGATGTTAGTATGGGAGGAAGAGTGGCAGAGGAGCTTATATTTGGAACCGACCATATTACAACAGG
TGCTTCCAGTGATTTTGATAATGCCACTAAAATAGCAAAGCGGATGGTTACCAAATTTGGAATGAGTGAAAAGCTTGGAGTTATGACCTACAGTGATACA
GGGAAACTAAGTCCAGAAACCCAATCTGCCATCGAACAAGAAATAAGAATCCTTCTAAGGGACTCATATGAACGAGCAAAACATATCTTGAAAACTCATG
CAAAGGAGCATAAGAATCTCGCAGAAGCTTTATTGACCTATGAGACTTTGGATGCCAAAGAGATTCAAATTGTTCTTGAGGGGAAAAAGTTGGAAGTGAG
ATGATAACTCTCTTGATATGGATGCTTGCTGGTTTTATTGCAAGAATACAAGTAGCATTGCAGTAGTCTACTTTTACAACGCTTTCCCCTCATTCTTGAT
GTGGTGTAATTGAAGGGTGTGAAATGCTTTGTCAATCATTTGTCACATTTATCCAGTTTGGGTTATTCTCATTATGACACCTATTGCAAATTAGCATCCC
ATGGCAAATATATTTTGAAAAAATAAAGAACTATCAGGATTGAAAACAGCTCTTTTGAGGAATGTCAATTAGTTATTAAGTTGAAAGTAATTAATGATTT
TATGTTTGGTTACTCTACTAGATTTGATAAAAATTGTGCCTTTAGCCTTCTATATACATCAGTGGAAACTTAAGATGCAGTAATTATGTTCCAGATTGAC
CATGAATAAAATATTTTTTAATCTAAATGTAGAGAAGTTGGGATTAAAAGCAGTCTCGGAAACACAGAGCCAGGAATATAGCCTTTTGGCATGGTGCCAT
GGCTCACATCTGTAATCCCAGCACTTTTGGAGGCTGAGGCGGGTGGATTGCTTGAGGCCAGGAGTTCGAGACCAGCCTGGCCAACGTGGTGAAACGCTGT
CTCTACTAAAATACAAAAAAATAGGGCTGGGCGCGGTTGCTCACGCCTGTAATCCCAGCACTTTTCAGAGGCCAAGGCGGGCAAATCACCTGAGGTCAAG
AGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAACATGCAAAAATTACCTGGGCATGGTGGCAGGTGCTTATAATCCCAGCTACTC
TGGGGGCCAAGGCAGGAGAATTGCTTGAGCCTGGGAGATGGAGGTTGCAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACT
CTGCCTCAAAAAAAAATTAAAATAAATTTAAATACAAAAAAAAATAGCCAGGTGTGGGGTGCATGCCTGGAATCCCAGCTACTTGAGAGGCTGAGGCACG
AGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCACAGGAGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTCTCAAAAA
AAAATTAAATAAATTATTATAACCTTTCAGAAATGCTGTGTGCATTTTCATGTTCTTTTTTTTAGCATTACTGTCACTCTCCCTAATGAAATGTACTTCA
GAGAAGCAGTATTTTGTTAAATAAATACATAACCTCATTCTGAATAATGTCCCTCATTTTGACTATAACTGTGCTTGGTTTCAAAAGCAAAATTAAACAA
AAATCTCAGTCCCCTCCGAAGTGAACTTTGTGTTACCCTGCGTCAGAAATGCCAAGTTGTGTTTACTTTTCATTCAGATTTTGTGAATATGAACATGCTG
TTATAGGATCTACAGATGAATATTTAACTCAATAGAAAAATTATTTTAGAACACATTGTATTGGTATTACAACCAGATTATATTCTTGACGTTGACTTCA
TTAAAATTATCTACAATTTCCTAATAA
  • refseq_YME1L1.F2 (forward primer)
  • refseq_YME1L1.R2 (reverse primer)
  • Single exon skipping

Frame 0

GGLSVVAVAVGRGGHFPFLGGVRGNGSEKKEKR
RAQRLPAGPWTEGHSFGRRVRSLRARRRCFPCRA
RCNPRLQFL*VISSMPSIHQKTLLFLSVECQFL
KTSIEM*FLSMRLPAVSVCSVTS*RSLTLFQLA
KEKYSKGTDPCSWSQQKG*RRAWTQPITGTSVQN
PSPSQSLLHLT*GTLDYLN*KLDRLISW*KIYF
LDFVKAKTFLPIGIHPMSLHNPSLKINMVT*IY
LVHYVPLACIDIIQELFKAFVQIFSTGQFSYSLG
VLKL*NQGHDVSSLPPRD*LKHRI*RHHS*RGF
FCGTEDQMLRVWTNS*KPKIYLKLTKMHLKLVL
RKVF*KLKHSHKKPMIP*GEPV*FSSFCCYSAFM
DF*KTHFYLSASGQQQGLILQ*ILSR*KMSPLN
MLKGWRKLNKNYRKLLNS*KIHKNLLFLEVNFQ
KEFF*LDPQGLERHFLPELWREKLMFLFIMLLDP
NLMRCLWVWEPAVSEIFLGKQRRMLLVLYLLMN
*ILLVGRELNLQCIHIQGRP*INFLLKWMVLNP
MKELS**EPQTSQRH*IMP*YVLVVLTCKLQFQG
QM*KVEQKF*NGISIK*SLINPLIQKL*LEVLL
AFPEQSWRIL*TRLH*KQLLMEKKWLP*RSWSF
PKTKF*WGLKEEVWKLITKTKPSQHIMNLVMPLL
HITQKMQCLSTKLQSCHGGQHLDMCPCYLRMTD
GMKLEPSCLHKWMLVWEEEWQRSLYLEPTILQQ
VLPVILIMPLK*QSGWLPNLE*VKSLEL*PTVIQ
GN*VQKPNLPSNKK*ESF*GTHMNEQNIS*KLM
QRSIRISQKLY*PMRLWMPKRFKLFLRGKSWK*
DDNSLDMDACWFYCKNTSSIAVVYFYNAFPSFLM
WCN*RV*NALSIICHIYPVWVILIMTPIAN*HP
MANIF*KNKELSGLKTALLRNVN*LLS*K*LMI
LCLVTLLDLIKIVPLAFYIHQWKLKMQ*LCSRLT
MNKIFFNLNVEKLGLKAVSETQSQEYSLLAWCH
GSHL*SQHFWRLRRVDCLRPGVRDQPGQRGETL
SLLKYKKIGLGAVAHACNPSTFQRPRRANHLRSR
V*DQPGQHGETPSLLNMQKLPGHGGRCL*SQLL
WGPRQENCLSLGDGGCSELRSCHCTPAWATEQD
SASKKN*NKFKYKKK*PGVGCMPGIPAT*EAEAR
ELLEPRRWRLQ*AKITGATALQPG*QSETLSQK
KIK*IIITFQKCCVHFHVLFFSITVTLPNEMYF
REAVFC*INT*PHSE*CPSF*L*LCLVSKAKLNK
NLSPLRSELCVTLRQKCQVVFTFHSDFVNMNML
L*DLQMNI*LNRKIILEHIVLVLQPDYILDVDF
IKIIYNFLI

Frame 1

ADCLSLQ*L*EGEAIFRFWEE*GATGRRKRKKE
GLSASPPGRGQRGTVSAGG*GR*GPAGDVFLVE
HGATPGYSSSESSHQCLPYTKKHFCFSQWSVSFS
KPASRCSS*A*GSQQ*VYVQ*LPDEA*HCFNWQ
RKNIRRVQIHVHGASKKDEEELGHNR*LAHPSR
TLLPLNPSFT*LKGPWII*TKNWTD*SAGRKSTS
WIL*RQKHFFPLAYIPCLCTILL*K*IW*LRYI
*YITFLLLVSTSFKSSSKHLFRSSVLASFHTVS
GF*NFEIKDTTSPVYLREIS*NTEYSAIIREGVS
FAGQRIRC*EFGQTHENQKYT*SSPRCI*NWFC
GRFSESSSTHTKNQ*FPKANPSDSLRSAAIRHL
WTSKKPIFICPLPDNNRA*FCSRSCPDEKCHL*T
C*RGGGS*TRITGSC*ILEKSTKIYYSWR*TSK
RNSFSWTPRDWKDTSCPSCGGRS*CSFLLCFWI
RI**DVCGCGSQPYQKSF*GSKGECSLCYIY**I
RFCWWEEN*ISNASIFKADHKSTSC*NGWF*TQ
*RSYHNRSHKLPRGIR*CLNTSWSF*HASYSSK
ARCKRSNRNFEMVSQ*NKV*SIR*SRNYSSRYCW
LFRSRVGESCEPGCIKSSC*WKRNGYHEGAGVF
QRQNSNGA*KKKCGN**QKQNHHSIS*IWSCHY
CILHKRCNAYQQSYNHATGANTWTCVPVT*E*QM
E*N*SPAACTNGC*YGRKSGRGAYIWNRPYYNR
CFQ*F**CH*NSKADGYQIWNE*KAWSYDLQ*Y
RETKSRNPICHRTRNKNPSKGLI*TSKTYLENSC
KGA*ESRRSFIDL*DFGCQRDSNCS*GEKVGSE
MITLLIWMLAGFIARIQVALQ*STFTTLSPHS*
CGVIEGCEMLCQSFVTFIQFGLFSL*HLLQISIP
WQIYFEKIKNYQD*KQLF*GMSISY*VESN**F
YVWLLY*I**KLCL*PSIYISGNLRCSNYVPD*
P*IKYFLI*M*RSWD*KQSRKHRARNIAFWHGAM
AHICNPSTFGG*GGWIA*GQEFETSLANVVKRC
LY*NTKK*GWARLLTPVIPALFRGQGGQIT*GQ
EFETSLANMVKPHLY*TCKNYLGMVAGAYNPSYS
GGQGRRIA*AWEMEVAVS*DHATALQPGQQSKT
LPQKKIKINLNTKKNSQVWGACLESQLLERLRH
ENCLNPGGGGCSEPRSQEPLHSSLGDRVRLCLKK
KLNKLL*PFRNAVCIFMFFFLALLSLSLMKCTS
EKQYFVK*IHNLILNNVPHFDYNCAWFQKQN*T
KISVPSEVNFVLPCVRNAKLCLLFIQIL*I*TCC
YRIYR*IFNSIEKLF*NTLYWYYNQIIFLTLTS
LKLSTIS**

Frame 2

RIVCRCSSCRKGRPFSVSGRSEGQRVGEKGKKK
GSAPPRRAVDRGAQFRQAGEVAEGPPEMFSLSS
TVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVS
QNQHRDVVPEHEAPSSECMFSDFLTKLNIVSIGK
GKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPE
PFSLSIPPSLNLRDLGLSELKIGQIDQLVENLL
PGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIF
STLRSSCLYRHHSRALQSICSDLQYWPVFIQSR
GFKTLKSRTRRLQSTSERLAETQNIAPSFVKGF
LLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFA
EGFLKAQALTQKTNDSLRRTRLILFVLLLFGIY
GLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFE
HVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPK
GILLVGPPGTGKTLLARAVAGEADVPFYYASGS
EFDEMFVGVGASRIRNLFREAKANAPCVIFIDE
LDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPN
EGVIIIGATNFPEALDNALIRPGRFDMQVTVPR
PDVKGRTEILKWYLNKIKFDQSVDPEIIARGTV
GFSGAELENLVNQAALKAAVDGKEMVTMKELEFS
KDKILMGPERRSVEIDNKNKTITAYHESGHAII
AYYTKDAMPINKATIMPRGPTLGHVSLLPENDR
WNETRAQLLAQMDVSMGGRVAEELIFGTDHITTG
ASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDT
GKLSPETQSAIEQEIRILLRDSYERAKHILKTH
AKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR
**LS*YGCLLVLLQEYK*HCSSLLLQRFPLILD
VV*LKGVKCFVNHLSHLSSLGYSHYDTYCKLAS
HGKYILKK*RTIRIENSSFEECQLVIKLKVINDF
MFGYSTRFDKNCAFSLLYTSVET*DAVIMFQID
HE*NIF*SKCREVGIKSSLGNTEPGI*PFGMVP
WLTSVIPALLEAEAGGLLEARSSRPAWPTW*NAV
STKIQKNRAGRGCSRL*SQHFSEAKAGKSPEVK
SLRPAWPTW*NPISTKHAKITWAWWQVLIIPAT
LGAKAGELLEPGRWRLQ*AEIMPLHSSLGNRARL
CLKKKLK*I*IQKKIARCGVHAWNPSYLRG*GT
RIA*TQEVEVAVSQDHRSHCTPAWVTE*DSVSK
KN*INYYNLSEMLCAFSCSFF*HYCHSP**NVLQ
RSSILLNKYITSF*IMSLILTITVLGFKSKIKQ
KSQSPPK*TLCYPASEMPSCVYFSFRFCEYEHA
VIGSTDEYLTQ*KNYFRTHCIGITTRLYS*R*LH
*NYLQFPN

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