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Sequences

Sequence NM_175069

AGCGCCGGAAGCGGTGAGGCACAGATGAGTAACGTGAATTTGTCCGTCTCCGACTTCTGGAGAGTGATGATGCGGGTGTGCTGGTTGGTGAGACAGGACA
GCCGGCACCAGCGAATCAGACTTCCACATTTGGAAGCAGTTGTGATTGGGCGTGGCCCAGAGACCAAGATCACTGATAAGAAATGTTCTCGACAGCAAGT
ACAGTTGAAAGCAGAGTGTAACAAGGGATATGTCAAGGTAAAGCAGGTAGGAGTCAATCCCACCAGCATTGACTCAGTCGTAATTGGGAAGGACCAAGAG
GTGAAGCTGCAGCCTGGCCAGGTTCTCCACATGGTGAATGAACTTTATCCATATATTGTAGAGTTTGAGGAAGAGGCAAAGAACCCTGGCCTGGAAACAC
ACAGGAAGAGAAAGAGATCAGGCAACAGTGATTCTATAGAAAGGGATGCTGCTCAGGAAGCTGAGGCTGGGACAGGGCTGGAACCTGGGAGCAACTCTGG
CCAATGCTCTGTGCCCCTAAAGAAGGGAAAAGATGCACCTATCAAAAAGGAATCCCTGGGCCACTGGAGTCAAGGCTTGAAGATTTCTATGCAGGACCCC
AAAATGCAGGTTTACAAAGATGAGCAGGTGGTGGTGATAAAGGATAAATACCCAAAGGCCCGTTACCATTGGCTGGTCTTACCGTGGACCTCCATTTCCA
GTCTGAAGGCTGTGGCCAGGGAACACCTTGAACTCCTTAAGCATATGCACACTGTGGGGGAAAAGGTGATTGTAGATTTTGCTGGGTCCAGCAAACTCCG
CTTCCGATTGGGCTACCACGCCATTCCGAGTATGAGCCATGTACATCTTCATGTGATCAGCCAGGATTTTGATTCTCCTTGCCTTAAAAACAAAAAACAT
TGGAATTCTTTCAATACAGAATACTTCCTAGAATCACAAGAGTAGCTGGGATTTGACTTTTCTTCCTTGCCTGCAGCTGTGATCGAGATGGTACAAGAGG
CTGGTAGAGTAACTGTCCGAGATGGGATGCCTGAGCTCTTGAAGCTGCCCCTTCGTTGTCATGAGTGCCAGCAGCTGCTGCCTTCCATTCCTCAGCTGAA
AGAACATCTCAGGAAGCACTGGACACAGTGATTCTGCAGAGCCTGAGCTGCTGCTGTGGTGTGGCCCACTGGAGCAAACTGCTGGCACCTATTCTGGGTT
GCTTGTGAACTTCTACTCATTTCCTAAATTAAAACATGCAGCTTTTTCACAAATTTATTCTATTATTGAGTGGCCACAATGTAGAGTGGCTCAAAGTACT
TCAGGATTAGGAATTTGGGTTTGTCATAGATGTATTCTCTGGTGAGGGTGGCTGGGATATACCTGACCCACCATCTTCAGAAGGACCCATGTCAGGTCTG
ACCATTGGGAGCAAAGCCATGTTCACACTGACCTAATGCAGAGTATGGAAGCATTGGGCTGGTTATACATTTCTGTTTCTTAGATTTATCCTCCGCCTCT
GTAGGCATGGACAACCTTTAATCAGAGCATCTAGAGTGGCCTCTTGTTTATCCTGAAGATACTGATGGGTCTTGTTTTCTGTTAGTCTGTTTTGTAATAT
TCTTTTCCCTTCCTTCATGGGGAGGCTTAGTTTGTCCAGTCCTTCCATGCCCTTCTATCCCAGATTACCTAAATGTTCCCTTCTCAGGAATTCTGTCTCA
TCAGTTCTTCACAGTGAGAAAAGAGGCTAGATGATGGTGTGGGGGGTTGGAGTTTTCTTCTAATACCGAGGGTTCCTGGCTGTGAGGAAACAGCCACATG
TTCGTCATGATTGAGCTGTGAAGTCTTCTTGGACCTGTTGTCTGAAAATAAAGTTAATTTGTTTGAGGCATCTCTCTTAAGTAGGTGGAAACTATTGAAG
TTCAGCTAACAATCACAGCATAGGTTCTGATGCATGGAAAGGTGGTTGGTGAATGAAAAAGTTGCGTAGAGCCACTACTTTCTTTTTCCCTGAGAATAAA
TTTGGATAAAACAGTTGTA
  • refseq_APTX.F4 (forward primer)
  • refseq_APTX.R4 (reverse primer)
  • Single exon skipping

Frame 0

SAGSGEAQMSNVNLSVSDFWRVMMRVCWLVRQD
SRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQV
QLKAECNKGYVKVKQVGVNPTSIDSVVIGKDQE
VKLQPGQVLHMVNELYPYIVEFEEEAKNPGLET
HRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSG
QCSVPLKKGKDAPIKKESLGHWSQGLKISMQDP
KMQVYKDEQVVVIKDKYPKARYHWLVLPWTSIS
SLKAVAREHLELLKHMHTVGEKVIVDFAGSSKLR
FRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKH
WNSFNTEYFLESQE*LGFDFSSLPAAVIEMVQE
AGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLK
EHLRKHWTQ*FCRA*AAAVVWPTGANCWHLFWV
ACELLLIS*IKTCSFFTNLFYY*VATM*SGSKY
FRIRNLGLS*MYSLVRVAGIYLTHHLQKDPCQV*
PLGAKPCSH*PNAEYGSIGLVIHFCFLDLSSAS
VGMDNL*SEHLEWPLVYPEDTDGSCFLLVCFVI
FFSLPSWGGLVCPVLPCPSIPDYLNVPFSGILSH
QFFTVRKEAR*WCGGLEFSSNTEGSWL*GNSHM
FVMIEL*SLLGPVV*K*S*FV*GISLK*VETIE
VQLTITA*VLMHGKVVGE*KSCVEPLLSFSLRIN
LDKTVV

Frame 1

APEAVRHR*VT*ICPSPTSGE**CGCAGW*DRT
AGTSESDFHIWKQL*LGVAQRPRSLIRNVLDSK
YS*KQSVTRDMSR*SR*ESIPPALTQS*LGRTKR
*SCSLARFSTW*MNFIHIL*SLRKRQRTLAWKH
TGRERDQATVIL*KGMLLRKLRLGQGWNLGATL
ANALCP*RREKMHLSKRNPWATGVKA*RFLCRTP
KCRFTKMSRWW**RINTQRPVTIGWSYRGPPFP
V*RLWPGNTLNSLSICTLWGKR*L*ILLGPANS
ASDWATTPFRV*AMYIFM*SARILILLALKTKNI
GILSIQNTS*NHKSSWDLTFLPCLQL*SRWYKR
LVE*LSEMGCLSS*SCPFVVMSASSCCLPFLS*
KNISGSTGHSDSAEPELLLWCGPLEQTAGTYSGL
LVNFYSFPKLKHAAFSQIYSIIEWPQCRVAQST
SGLGIWVCHRCILW*GWLGYT*PTIFRRTHVRS
DHWEQSHVHTDLMQSMEALGWLYISVS*IYPPPL
*AWTTFNQSI*SGLLFILKILMGLVFC*SVL*Y
SFPFLHGEA*FVQSFHALLSQIT*MFPSQEFCL
ISSSQ*EKRLDDGVGGWSFLLIPRVPGCEETATC
SS*LSCEVFLDLLSENKVNLFEASLLSRWKLLK
FS*QSQHRF*CMERWLVNEKVA*SHYFLFP*E*
IWIKQL

Frame 2

RRKR*GTDE*REFVRLRLLESDDAGVLVGETGQ
PAPANQTSTFGSSCDWAWPRDQDH**EMFSTAS
TVESRV*QGICQGKAGRSQSHQH*LSRNWEGPR
GEAAAWPGSPHGE*TLSIYCRV*GRGKEPWPGNT
QEEKEIRQQ*FYRKGCCSGS*GWDRAGTWEQLW
PMLCAPKEGKRCTYQKGIPGPLESRLEDFYAGP
QNAGLQR*AGGGDKG*IPKGPLPLAGLTVDLHFQ
SEGCGQGTP*TP*AYAHCGGKGDCRFCWVQQTP
LPIGLPRHSEYEPCTSSCDQPGF*FSLP*KQKT
LEFFQYRILPRITRVAGI*LFFLACSCDRDGTRG
W*SNCPRWDA*ALEAAPSLS*VPAAAAFHSSAE
RTSQEALDTVILQSLSCCCGVAHWSKLLAPILG
CL*TSTHFLN*NMQLFHKFILLLSGHNVEWLKVL
QD*EFGFVIDVFSGEGGWDIPDPPSSEGPMSGL
TIGSKAMFTLT*CRVWKHWAGYTFLFLRFILRL
CRHGQPLIRASRVASCLS*RY*WVLFSVSLFCNI
LFPSFMGRLSLSSPSMPFYPRLPKCSLLRNSVS
SVLHSEKRG*MMVWGVGVFF*YRGFLAVRKQPH
VRHD*AVKSSWTCCLKIKLICLRHLS*VGGNY*S
SANNHSIGSDAWKGGW*MKKLRRATTFFFPENK
FG*NSC

Sequence NM_175071

AGCGCCGGAAGCGGTGAGGCACAGATGAGTAACGTGAATTTGTCCGTCTCCGACTTCTGGAGAGTGATGATGCGGGTGTGCTGGTTGGTGAGACAGGACA
GCCGGCACCAGCGAATCAGACTTCCACATTTGGAAGCAGTTGTGATTGGGCGTGGCCCAGAGACCAAGATCACTGATAAGAAATGTTCTCGACAGCAAGT
ACAGTTGAAAGCAGAGTGTAACAAGGGATATGTCAAGGTAAAGCAGAGTTTGAGGAAGAGGCAAAGAACCCTGGCCTGGAAACACACAGGAAGAGAAAGA
GATCAGGCAACAGTGATTCTATAGAAAGGGATGCTGCTCAGGAAGCTGAGGCTGGGACAGGGCTGGAACCTGGGAGCAACTCTGGCCAATGCTCTGTGCC
CCTAAAGAAGGGAAAAGATGCACCTATCAAAAAGGAATCCCTGGGCCACTGGAGTCAAGGCTTGAAGATTTCTATGCAGGACCCCAAAATGCAGGTTTAC
AAAGATGAGCAGGTGGTGGTGATAAAGGATAAATACCCAAAGGCCCGTTACCATTGGCTGGTCTTACCGTGGACCTCCATTTCCAGTCTGAAGGCTGTGG
CCAGGGAACACCTTGAACTCCTTAAGCATATGCACACTGTGGGGGAAAAGGTGATTGTAGATTTTGCTGGGTCCAGCAAACTCCGCTTCCGATTGGGCTA
CCACGCCATTCCGAGTATGAGCCATGTACATCTTCATGTGATCAGCCAGGATTTTGATTCTCCTTGCCTTAAAAACAAAAAACATTGGAATTCTTTCAAT
ACAGAATACTTCCTAGAATCACAAGCTGTGATCGAGATGGTACAAGAGGCTGGTAGAGTAACTGTCCGAGATGGGATGCCTGAGCTCTTGAAGCTGCCCC
TTCGTTGTCATGAGTGCCAGCAGCTGCTGCCTTCCATTCCTCAGCTGAAAGAACATCTCAGGAAGCACTGGACACAGTGATTCTGCAGAGCCTGAGCTGC
TGCTGTGGTGTGGCCCACTGGAGCAAACTGCTGGCACCTATTCTGGGTTGCTTGTGAACTTCTACTCATTTCCTAAATTAAAACATGCAGCTTTTTCACA
AATTTATTCTATTATTGAGTGGCCACAATGTAGAGTGGCTCAAAGTACTTCAGGATTAGGAATTTGGGTTTGTCATAGATGTATTCTCTGGTGAGGGTGG
CTGGGATATACCTGACCCACCATCTTCAGAAGGACCCATGTCAGGTCTGACCATTGGGAGCAAAGCCATGTTCACACTGACCTAATGCAGAGTATGGAAG
CATTGGGCTGGTTATACATTTCTGTTTCTTAGATTTATCCTCCGCCTCTGTAGGCATGGACAACCTTTAATCAGAGCATCTAGAGTGGCCTCTTGTTTAT
CCTGAAGATACTGATGGGTCTTGTTTTCTGTTAGTCTGTTTTGTAATATTCTTTTCCCTTCCTTCATGGGGAGGCTTAGTTTGTCCAGTCCTTCCATGCC
CTTCTATCCCAGATTACCTAAATGTTCCCTTCTCAGGAATTCTGTCTCATCAGTTCTTCACAGTGAGAAAAGAGGCTAGATGATGGTGTGGGGGGTTGGA
GTTTTCTTCTAATACCGAGGGTTCCTGGCTGTGAGGAAACAGCCACATGTTCGTCATGATTGAGCTGTGAAGTCTTCTTGGACCTGTTGTCTGAAAATAA
AGTTAATTTGTTTGAGGCATCTCTCTTAAGTAGGTGGAAACTATTGAAGTTCAGCTAACAATCACAGCATAGGTTCTGATGCATGGAAAGGTGGTTGGTG
AATGAAAAAGTTGCGTAGAGCCACTACTTTCTTTTTCCCTGAGAATAAATTTGGATAAAACAGTTGTA
  • refseq_APTX.F4 (forward primer)
  • refseq_APTX.R4 (reverse primer)
  • Single exon skipping

Frame 0

SAGSGEAQMSNVNLSVSDFWRVMMRVCWLVRQD
SRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQV
QLKAECNKGYVKVKQSLRKRQRTLAWKHTGRER
DQATVIL*KGMLLRKLRLGQGWNLGATLANALC
P*RREKMHLSKRNPWATGVKA*RFLCRTPKCRFT
KMSRWW**RINTQRPVTIGWSYRGPPFPV*RLW
PGNTLNSLSICTLWGKR*L*ILLGPANSASDWA
TTPFRV*AMYIFM*SARILILLALKTKNIGILSI
QNTS*NHKL*SRWYKRLVE*LSEMGCLSS*SCP
FVVMSASSCCLPFLS*KNISGSTGHSDSAEPEL
LLWCGPLEQTAGTYSGLLVNFYSFPKLKHAAFSQ
IYSIIEWPQCRVAQSTSGLGIWVCHRCILW*GW
LGYT*PTIFRRTHVRSDHWEQSHVHTDLMQSME
ALGWLYISVS*IYPPPL*AWTTFNQSI*SGLLFI
LKILMGLVFC*SVL*YSFPFLHGEA*FVQSFHA
LLSQIT*MFPSQEFCLISSSQ*EKRLDDGVGGW
SFLLIPRVPGCEETATCSS*LSCEVFLDLLSENK
VNLFEASLLSRWKLLKFS*QSQHRF*CMERWLV
NEKVA*SHYFLFP*E*IWIKQL

Frame 1

APEAVRHR*VT*ICPSPTSGE**CGCAGW*DRT
AGTSESDFHIWKQL*LGVAQRPRSLIRNVLDSK
YS*KQSVTRDMSR*SRV*GRGKEPWPGNTQEEKE
IRQQ*FYRKGCCSGS*GWDRAGTWEQLWPMLCA
PKEGKRCTYQKGIPGPLESRLEDFYAGPQNAGL
QR*AGGGDKG*IPKGPLPLAGLTVDLHFQSEGCG
QGTP*TP*AYAHCGGKGDCRFCWVQQTPLPIGL
PRHSEYEPCTSSCDQPGF*FSLP*KQKTLEFFQ
YRILPRITSCDRDGTRGW*SNCPRWDA*ALEAAP
SLS*VPAAAAFHSSAERTSQEALDTVILQSLSC
CCGVAHWSKLLAPILGCL*TSTHFLN*NMQLFH
KFILLLSGHNVEWLKVLQD*EFGFVIDVFSGEGG
WDIPDPPSSEGPMSGLTIGSKAMFTLT*CRVWK
HWAGYTFLFLRFILRLCRHGQPLIRASRVASCL
S*RY*WVLFSVSLFCNILFPSFMGRLSLSSPSMP
FYPRLPKCSLLRNSVSSVLHSEKRG*MMVWGVG
VFF*YRGFLAVRKQPHVRHD*AVKSSWTCCLKI
KLICLRHLS*VGGNY*SSANNHSIGSDAWKGGW*
MKKLRRATTFFFPENKFG*NSC

Frame 2

RRKR*GTDE*REFVRLRLLESDDAGVLVGETGQ
PAPANQTSTFGSSCDWAWPRDQDH**EMFSTAS
TVESRV*QGICQGKAEFEEEAKNPGLETHRKRK
RSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVP
LKKGKDAPIKKESLGHWSQGLKISMQDPKMQVY
KDEQVVVIKDKYPKARYHWLVLPWTSISSLKAV
AREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGY
HAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFN
TEYFLESQAVIEMVQEAGRVTVRDGMPELLKLP
LRCHECQQLLPSIPQLKEHLRKHWTQ*FCRA*AA
AVVWPTGANCWHLFWVACELLLIS*IKTCSFFT
NLFYY*VATM*SGSKYFRIRNLGLS*MYSLVRV
AGIYLTHHLQKDPCQV*PLGAKPCSH*PNAEYGS
IGLVIHFCFLDLSSASVGMDNL*SEHLEWPLVY
PEDTDGSCFLLVCFVIFFSLPSWGGLVCPVLPC
PSIPDYLNVPFSGILSHQFFTVRKEAR*WCGGLE
FSSNTEGSWL*GNSHMFVMIEL*SLLGPVV*K*
S*FV*GISLK*VETIEVQLTITA*VLMHGKVVG
E*KSCVEPLLSFSLRINLDKTVV

Sequence NM_175073

AGCGCCGGAAGCGGTGAGGCACAGATGAGTAACGTGAATTTGTCCGTCTCCGACTTCTGGAGATTTATTTTTTTTAGATGAGGTGTTGCTGTGTTGCCCA
AGCTGGACTTGAACCCCTAGGCTCAAGCAATCCTTCCACCTCAGTCTCCCAAGTAGCAGGGACTACAGAGTGATGATGCGGGTGTGCTGGTTGGTGAGAC
AGGACAGCCGGCACCAGCGAATCAGACTTCCACATTTGGAAGCAGTTGTGATTGGGCGTGGCCCAGAGACCAAGATCACTGATAAGAAATGTTCTCGACA
GCAAGTACAGTTGAAAGCAGAGTGTAACAAGGGATATGTCAAGGTAAAGCAGGTAGGAGTCAATCCCACCAGCATTGACTCAGTCGTAATTGGGAAGGAC
CAAGAGGTGAAGCTGCAGCCTGGCCAGGTTCTCCACATGGTGAATGAACTTTATCCATATATTGTAGAGTTTGAGGAAGAGGCAAAGAACCCTGGCCTGG
AAACACACAGGAAGAGAAAGAGATCAGGCAACAGTGATTCTATAGAAAGGGATGCTGCTCAGGAAGCTGAGGCTGGGACAGGGCTGGAACCTGGGAGCAA
CTCTGGCCAATGCTCTGTGCCCCTAAAGAAGGGAAAAGATGCACCTATCAAAAAGGAATCCCTGGGCCACTGGAGTCAAGGCTTGAAGATTTCTATGCAG
GACCCCAAAATGCAGGTTTACAAAGATGAGCAGGTGGTGGTGATAAAGGATAAATACCCAAAGGCCCGTTACCATTGGCTGGTCTTACCGTGGACCTCCA
TTTCCAGTCTGAAGGCTGTGGCCAGGGAACACCTTGAACTCCTTAAGCATATGCACACTGTGGGGGAAAAGGTGATTGTAGATTTTGCTGGGTCCAGCAA
ACTCCGCTTCCGATTGGGCTACCACGCCATTCCGAGTATGAGCCATGTACATCTTCATGTGATCAGCCAGGATTTTGATTCTCCTTGCCTTAAAAACAAA
AAACATTGGAATTCTTTCAATACAGAATACTTCCTAGAATCACAAGCTGTGATCGAGATGGTACAAGAGGCTGGTAGAGTAACTGTCCGAGATGGGATGC
CTGAGCTCTTGAAGCTGCCCCTTCGTTGTCATGAGTGCCAGCAGCTGCTGCCTTCCATTCCTCAGCTGAAAGAACATCTCAGGAAGCACTGGACACAGTG
ATTCTGCAGAGCCTGAGCTGCTGCTGTGGTGTGGCCCACTGGAGCAAACTGCTGGCACCTATTCTGGGTTGCTTGTGAACTTCTACTCATTTCCTAAATT
AAAACATGCAGCTTTTTCACAAATTTATTCTATTATTGAGTGGCCACAATGTAGAGTGGCTCAAAGTACTTCAGGATTAGGAATTTGGGTTTGTCATAGA
TGTATTCTCTGGTGAGGGTGGCTGGGATATACCTGACCCACCATCTTCAGAAGGACCCATGTCAGGTCTGACCATTGGGAGCAAAGCCATGTTCACACTG
ACCTAATGCAGAGTATGGAAGCATTGGGCTGGTTATACATTTCTGTTTCTTAGATTTATCCTCCGCCTCTGTAGGCATGGACAACCTTTAATCAGAGCAT
CTAGAGTGGCCTCTTGTTTATCCTGAAGATACTGATGGGTCTTGTTTTCTGTTAGTCTGTTTTGTAATATTCTTTTCCCTTCCTTCATGGGGAGGCTTAG
TTTGTCCAGTCCTTCCATGCCCTTCTATCCCAGATTACCTAAATGTTCCCTTCTCAGGAATTCTGTCTCATCAGTTCTTCACAGTGAGAAAAGAGGCTAG
ATGATGGTGTGGGGGGTTGGAGTTTTCTTCTAATACCGAGGGTTCCTGGCTGTGAGGAAACAGCCACATGTTCGTCATGATTGAGCTGTGAAGTCTTCTT
GGACCTGTTGTCTGAAAATAAAGTTAATTTGTTTGAGGCATCTCTCTTAAGTAGGTGGAAACTATTGAAGTTCAGCTAACAATCACAGCATAGGTTCTGA
TGCATGGAAAGGTGGTTGGTGAATGAAAAAGTTGCGTAGAGCCACTACTTTCTTTTTCCCTGAGAATAAATTTGGATAAAACAGTTGTA
  • refseq_APTX.F4 (forward primer)
  • refseq_APTX.R4 (reverse primer)
  • Single exon skipping

Frame 0

SAGSGEAQMSNVNLSVSDFWRFIFFR*GVAVLP
KLDLNP*AQAILPPQSPK*QGLQSDDAGVLVGET
GQPAPANQTSTFGSSCDWAWPRDQDH**EMFST
ASTVESRV*QGICQGKAGRSQSHQH*LSRNWEG
PRGEAAAWPGSPHGE*TLSIYCRV*GRGKEPWPG
NTQEEKEIRQQ*FYRKGCCSGS*GWDRAGTWEQ
LWPMLCAPKEGKRCTYQKGIPGPLESRLEDFYA
GPQNAGLQR*AGGGDKG*IPKGPLPLAGLTVDLH
FQSEGCGQGTP*TP*AYAHCGGKGDCRFCWVQQ
TPLPIGLPRHSEYEPCTSSCDQPGF*FSLP*KQ
KTLEFFQYRILPRITSCDRDGTRGW*SNCPRWDA
*ALEAAPSLS*VPAAAAFHSSAERTSQEALDTV
ILQSLSCCCGVAHWSKLLAPILGCL*TSTHFLN
*NMQLFHKFILLLSGHNVEWLKVLQD*EFGFVID
VFSGEGGWDIPDPPSSEGPMSGLTIGSKAMFTL
T*CRVWKHWAGYTFLFLRFILRLCRHGQPLIRA
SRVASCLS*RY*WVLFSVSLFCNILFPSFMGRLS
LSSPSMPFYPRLPKCSLLRNSVSSVLHSEKRG*
MMVWGVGVFF*YRGFLAVRKQPHVRHD*AVKSS
WTCCLKIKLICLRHLS*VGGNY*SSANNHSIGSD
AWKGGW*MKKLRRATTFFFPENKFG*NSC

Frame 1

APEAVRHR*VT*ICPSPTSGDLFFLDEVLLCCP
SWT*TPRLKQSFHLSLPSSRDYRVMMRVCWLVR
QDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQ
QVQLKAECNKGYVKVKQVGVNPTSIDSVVIGKD
QEVKLQPGQVLHMVNELYPYIVEFEEEAKNPGL
ETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSN
SGQCSVPLKKGKDAPIKKESLGHWSQGLKISMQ
DPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTS
ISSLKAVAREHLELLKHMHTVGEKVIVDFAGSSK
LRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNK
KHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGM
PELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ*
FCRA*AAAVVWPTGANCWHLFWVACELLLIS*I
KTCSFFTNLFYY*VATM*SGSKYFRIRNLGLS*
MYSLVRVAGIYLTHHLQKDPCQV*PLGAKPCSH*
PNAEYGSIGLVIHFCFLDLSSASVGMDNL*SEH
LEWPLVYPEDTDGSCFLLVCFVIFFSLPSWGGL
VCPVLPCPSIPDYLNVPFSGILSHQFFTVRKEAR
*WCGGLEFSSNTEGSWL*GNSHMFVMIEL*SLL
GPVV*K*S*FV*GISLK*VETIEVQLTITA*VL
MHGKVVGE*KSCVEPLLSFSLRINLDKTVV

Frame 2

RRKR*GTDE*REFVRLRLLEIYFF*MRCCCVAQ
AGLEPLGSSNPSTSVSQVAGTTE**CGCAGW*D
RTAGTSESDFHIWKQL*LGVAQRPRSLIRNVLD
SKYS*KQSVTRDMSR*SR*ESIPPALTQS*LGRT
KR*SCSLARFSTW*MNFIHIL*SLRKRQRTLAW
KHTGRERDQATVIL*KGMLLRKLRLGQGWNLGA
TLANALCP*RREKMHLSKRNPWATGVKA*RFLCR
TPKCRFTKMSRWW**RINTQRPVTIGWSYRGPP
FPV*RLWPGNTLNSLSICTLWGKR*L*ILLGPA
NSASDWATTPFRV*AMYIFM*SARILILLALKTK
NIGILSIQNTS*NHKL*SRWYKRLVE*LSEMGC
LSS*SCPFVVMSASSCCLPFLS*KNISGSTGHS
DSAEPELLLWCGPLEQTAGTYSGLLVNFYSFPKL
KHAAFSQIYSIIEWPQCRVAQSTSGLGIWVCHR
CILW*GWLGYT*PTIFRRTHVRSDHWEQSHVHT
DLMQSMEALGWLYISVS*IYPPPL*AWTTFNQSI
*SGLLFILKILMGLVFC*SVL*YSFPFLHGEA*
FVQSFHALLSQIT*MFPSQEFCLISSSQ*EKRL
DDGVGGWSFLLIPRVPGCEETATCSS*LSCEVFL
DLLSENKVNLFEASLLSRWKLLKFS*QSQHRF*
CMERWLVNEKVA*SHYFLFP*E*IWIKQL

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