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Sequences

Sequence NM_145642

ACTCTGGGGAAAGGAGGGTACAACCACATGTAAATTTTATTATAATGATGGTATAATGAACTTGGGGTGACCTGAGGGCATGTTTTTGTGTTACTGGGCA TGTGCCCCTTTAGGAGACTTCCACCTGTGCCTTACTTTCTCTTTCTTTGGGATGTGCTGGCCACAGACTTTACCAAAAACTCCATCCATTAGGATGGCAT TAGGACGGTTCTGGGGCTAAACTTAGGTGGGCCAGGGGCTGTTTCACTGTCAGCCTTTCTACTCTCTTTTCTTACCCACTCCTAGCTGCTAATGTCTATT TAACTACCTAATATTTCCCCCTTTAGAGAAAAAAAGCCAAATTTTTGGGTAGATCGGTGACAATTAATCTGGCTACTTCCTGCTGACAAGAGGCAGTGGT AATAATTGGGTTCTCTTTTTTGCTCTCTTGTAGCTGGTAGGTTGGGCAGAGAAAAGTGGTGGCCATCCAAGGGGCCCACGTAGATATCAGACATGGTTGA GACCTCGCGGTAACCTTGTGTAGAATCATTTGGAGTTTTATGGATTCTAGGTGGGAAGAAACAAAACAACCTTGTAAATCAAATGAGCATCGTTTGAAAG CTATAAGTTGTATAAAGCTGTTTTAGGACCAAGAAAGGGGGCTAACCAGGAAAACCAGGACCAGTTGTTAAATTTCCACCAGTCAAAGCCTCCTGAAACT CTGTTTTCCATTAACTTGTTGGCCCTGTCTGTAATTTTTTTAAGTTGGTTTGCACTTTACCTGATTGGTTGATGAAAACAGCAATGTTTATCAAGTGTTG CACAAGCTCCCCCTTGATTGGCTGTGAGCAAATTAAAAGCTCATCAATTTCATAAGACTATGCTTGCTAATGAAGCAATTTGTTCTGAAAGGGTATTGAC CTGGTTAGTTAGATTAATAATTTGTTGAGTAATTTTTAAGAAGAGTTTCTGGGCAGTAAAAATGGAGTTAAGGAGGTCCTCCAGTTCCCGTGCCAATACC AGCCAGAACGCCAATTATAGTCAGTGCTGTTAAAACTCCTCTTTCAGTTTTACCAGATTGAGCGTGTATAGGGAGGGGAATGCTATCGATAAGAGTGAGT TTGGGGATGATGTAAACTAGGGCCAAATCCCCGTTTAATTAGCAGACAAGCAGAGATATGCCTTGTTTCTATACAAAAATGTGATTTGTCATGTTAAGAC AAATATCAACAGTGATACTAAAGTAGGGTTTTTCCATGCTGTGTAAGTCTGCTTTAATACCCTCAGAAGTGGAAGTCAAGGCTAGTTCATGTAATGGGGG AACACAGGCAGTACTTGACAGAATGAAAGAGGAATCAAAAGCCCAATTAGAGGAAGGAGTGATGGGATCCCAACCAATATTGTGAAATTATGGGGAGCTG CAGTTTTTTGCAATGATTTTGCCCGAAGTTGTGAGACTGAAACCAGAAGTTGTTATGTTTAAAATGATATTCTGGTGTGGGTCTGGGGAAAAGGGTAGAT CCAGAATAGCTGGCTTCTTTCCACATAGTGGTTCTGTTGGGGGGCTTGGGAAATGAATAAAACACAAAGAAGAATTAGAATATCAGGGTATATCTCAGAG CCTGGAGAACGTGTCTGGTTATTATGCAGATGCACGGCTGGAGGTGGGATCCACACAGCTCAGAACAGCTGGATCTTGCTCACACTCTTTCAAGAGAAGC TTCCTTGAAAAGAAACGCTTTACTGAAGAGGCCACCAAATACTTCCGGGAGAGAGTCAGCCCAGTGCATCTGCAAATCCTGCTGACTAACAATGAAGCCT GGAAGAGATTCGTGACTGCGGCTGAATTGCCCAGGGATGAGGCAGATGCTCTCTACGAAGCTCTGAAGAAGCTTAGAACATATGCAGCTATTGAGGACGA ATATGTGCAGCAGAAAGATGAGCAGTTTAGGGAATGGTTTTTGAAAGAGTTTCCCCAAGTCAAGAGGAAGATCCAGGAGTCCATAGAAAAGCTTCGTGCC CTTGCAAATGGTATTGAAGAGGTCCACAGAGGCTGCACCATCTCCAATGTGGTGTCCAGCTCCACTGGCGCTGCCTCTGGCATCATGTCCCTTGCTGGTC TTGTTTTGGCACCATTTACAGCAGGGACGAGTCTGGCCCTTACTGCAGCTGGGGTAGGGCTGGGAGCAGCGTCTGCTGTGACTGGGATCACCACCAGCAT CGTGGAGCACTCATACACATCATCAGCAGAAGCTGAAGCCAGCAGGCTGACTGCAACCAGCATTGACCGATTGAAGGTATTTAAGGAAGTTATGCGTGAC ATCACACCCAACTTACTTTCCCTTCTTAATAATTATTACGAAGCCACACAAACCATTGGGAGTGAAATCCGTGCCATCAGGCAAGCCAGAGCCAGGGCCC GACTCCCTGTGACCACCTGGCGAATCTCAGCTGGAAGTGGTGGTCAAGCAGAGAGAACGATTGCAGGCACCACCCGGGCAGTGAGCAGAGGAGCCCGGAT CCTGAGTGCGACCACTTCAGGCATCTTCCTTGCACTGGATGTGGTCAACCTTGTATACGAGTCAAAGCACTTGCATGAGGGGGCAAAGTCTGCATCTGCT GAGGAGCTGAGGCGGCAGGCTCAGGAGCTGGAGGAGAATCTAATGGAGCTCACTCAGATCTATCAGCGTCTGAATCCATGCCATACCCACTGACCCCAGA CCAGTGCAGCCAGCAGGGGAGGTGAGCCATACACAGGCCACGACAAAATGCAGGCATTTTATTAGGGGGATAAAGAGGGCAAGGTAAAGTTTATGGAGCT GAGTGTTAGTGACTTTGGCATTTCTGTAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAAGTGCACCAAGGAGAAGGCAGGAATGCTGGAGCCT GGAATAAGGGAGGAGAGGGGACTGGAGAGTGTGGGGAATAGGAAGAAGAAATTTCCTTTAGACTAACGAATATATTGGGGGGAGGAATAGAGGGGAGGTG TGCAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGCAGAAAGCCGAAGAGTTAGAACTTTTGGATACAGCAGAAGAAACAGCGGCTC CACTACCGACCTGCCCCCGGTTCGATGTCCTTCCAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCTGTCTTGTC CTCCTGGAAGTGTATCTCAGTCAGCCAGTGGCTTCTTGATGATGGCGGTGGAGGTGGTGGTTGTAGTGTGATGGATCCCCTTTAGGTTATTTAGGGGTAT ATGTCCCCTGCTTGAACCCTGAAGGCCAGGTAATGAGCCATGGCCATTGTCCCCAGCTGAGGACCAGGTGTCTCTAAAAACCCAAACATCCTGGAGAGTA TGCGAGAACCTACCAAGAAAAACAGTCTCATTACTCATATACAGCAGGCAAAGAGACAGAAAATTAACTGAAAAGCAGTTTAGAGACTGGGGGAGGCCGG ATCTCTAGAGCCATCCTGCTGAGTGCCCTGTGTGTAAGTCCTAATAAACTCACCTACTCACCAA

refseq_APOL3.F1 (forward primer)
refseq_APOL3.R1 (reverse primer)
Single exon skipping

Frame 0

TLGKGGYNHM*ILL**WYNELGVT*GHVFVLLG MCPFRRLPPVPYFLFLWDVLATDFTKNSIH*DGI RTVLGLNLGGPGAVSLSAFLLSFLTHS*LLMSI *LPNISPFREKKPNFWVDR*QLIWLLPADKRQW **LGSLFCSLVAGRLGREKWWPSKGPT*ISDMVE TSR*PCVESFGVLWILGGKKQNNLVNQMSIV*K L*VV*SCFRTKKGG*PGKPGPVVKFPPVKAS*N SVFH*LVGPVCNFFKLVCTLPDWLMKTAMFIKCC TSSPLIGCEQIKSSSIS*DYAC**SNLF*KGID LVS*INNLLSNF*EEFLGSKNGVKEVLQFPCQY QPERQL*SVLLKLLFQFYQIERV*GGECYR*E*V WG*CKLGPNPRLISRQAEICLVSIQKCDLSC*D KYQQ*Y*SRVFPCCVSLL*YPQKWKSRLVHVMG EHRQYLTE*KRNQKPN*RKE*WDPNQYCEIMGSC SFLQ*FCPKL*D*NQKLLCLK*YSGVGLGKRVD PE*LASFHIVVLLGGLGNE*NTKKN*NIRVYLR AWRTCLVIMQMHGWRWDPHSSEQLDLAHTLSREA SLKRNALLKRPPNTSGRESAQCICKSC*LTMKP GRDS*LRLNCPGMRQMLSTKL*RSLEHMQLLRT NMCSRKMSSLGNGF*KSFPKSRGRSRSP*KSFVP LQMVLKRSTEAAPSPMWCPAPLALPLASCPLLV LFWHHLQQGRVWPLLQLG*GWEQRLL*LGSPPA SWSTHTHHQQKLKPAG*LQPALTD*RYLRKLCVT SHPTYFPFLIIITKPHKPLGVKSVPSGKPEPGP DSL*PPGESQLEVVVKQRERLQAPPGQ*AEEPG S*VRPLQASSLHWMWSTLYTSQSTCMRGQSLHLL RS*GGRLRSWRRI*WSSLRSISV*IHAIPTDPR PVQPAGEVSHTQATTKCRHFIRGIKRAR*SLWS *VLVTLAFL*LSTAGEGLMQMASAPRRRQECWSL E*GRRGDWRVWGIGRRNFL*TNEYIGGRNRGEV CRNQQ*EGQEKKELKMQKAEELELLDTAEETAA PLPTCPRFDVLPRMKSFPGDGPLPCLSSIHSVLS SWKCISVSQWLLDDGGGGGGCSVMDPL*VI*GY MSPA*TLKAR**AMAIVPS*GPGVSKNPNILES MREPTKKNSLITHIQQAKRQKIN*KAV*RLGEAG SLEPSC*VPCV*VLINSPTHQ

Frame 1

LWGKEGTTTCKFYYNDGIMNLG*PEGMFLCYWA CAPLGDFHLCLTFSFFGMCWPQTLPKTPSIRMA LGRFWG*T*VGQGLFHCQPFYSLFLPTPSC*CLF NYLIFPPLEKKSQIFG*IGDN*SGYFLLTRGSG NNWVLFFALL*LVGWAEKSGGHPRGPRRYQTWL RPRGNLV*NHLEFYGF*VGRNKTTL*IK*ASFES YKLYKAVLGPRKGANQENQDQLLNFHQSKPPET LFSINLLALSVIFLSWFALYLIG**KQQCLSSV AQAPP*LAVSKLKAHQFHKTMLANEAICSERVLT WLVRLIIC*VIFKKSFWAVKMELRRSSSSRANT SQNANYSQCC*NSSFSFTRLSVYREGNAIDKSE FGDDVN*GQIPV*LADKQRYALFLYKNVICHVKT NINSDTKVGFFHAV*VCFNTLRSGSQG*FM*WG NTGST*QNERGIKSPIRGRSDGIPTNIVKLWGA AVFCNDFARSCETETRSCYV*NDILVWVWGKG*I QNSWLLST*WFCWGAWEMNKTQRRIRISGYISE PGERVWLLCRCTAGGGIHTAQNSWILLTLFQEK LP*KETLY*RGHQILPGESQPSASANPAD*Q*SL EEIRDCG*IAQG*GRCSLRSSEEA*NICSY*GR ICAAER*AV*GMVFERVSPSQEEDPGVHRKASC PCKWY*RGPQRLHHLQCGVQLHWRCLWHHVPCWS CFGTIYSRDESGPYCSWGRAGSSVCCDWDHHQH RGALIHIISRS*SQQADCNQH*PIEGI*GSYA* HHTQLTFPS**LLRSHTNHWE*NPCHQASQSQGP TPCDHLANLSWKWWSSRENDCRHHPGSEQRSPD PECDHFRHLPCTGCGQPCIRVKALA*GGKVCIC *GAEAAGSGAGGESNGAHSDLSASESMPYPLTPD QCSQQGR*AIHRPRQNAGILLGG*RGQGKVYGA EC**LWHFCS*AQQGRG*CRWQVHQGEGRNAGA WNKGGEGTGECGE*EEEISFRLTNILGGGIEGRC AGTSNEKARKRKS*KCRKPKS*NFWIQQKKQRL HYRPAPGSMSFQE*SLSLVMVPCPVFPASTLSC PPGSVSQSASGFLMMAVEVVVVV*WIPFRLFRGI CPLLEP*RPGNEPWPLSPAEDQVSLKTQTSWRV CENLPRKTVSLLIYSRQRDRKLTEKQFRDWGRP DL*SHPAECPVCKS**THLLT

Frame 2

SGERRVQPHVNFIIMMV**TWGDLRACFCVTGH VPL*ETSTCALLSLSLGCAGHRLYQKLHPLGWH *DGSGAKLRWARGCFTVSLSTLFSYPLLAANVY LTT*YFPL*RKKAKFLGRSVTINLATSC*QEAVV IIGFSFLLSCSW*VGQRKVVAIQGAHVDIRHG* DLAVTLCRIIWSFMDSRWEETKQPCKSNEHRLK AISCIKLF*DQERGLTRKTRTSC*ISTSQSLLKL CFPLTCWPCL*FF*VGLHFT*LVDENSNVYQVL HKLPLDWL*AN*KLINFIRLCLLMKQFVLKGY* PG*LD**FVE*FLRRVSGQ*KWS*GGPPVPVPIP ARTPIIVSAVKTPLSVLPD*ACIGRGMLSIRVS LGMM*TRAKSPFN*QTSRDMPCFYTKM*FVMLR QISTVILK*GFSMLCKSALIPSEVEVKASSCNGG TQAVLDRMKEESKAQLEEGVMGSQPIL*NYGEL QFFAMILPEVVRLKPEVVMFKMIFWCGSGEKGR SRIAGFFPHSGSVGGLGK*IKHKEELEYQGISQS LENVSGYYADARLEVGSTQLRTAGSCSHSFKRS FLEKKRFTEEATKYFRERVSPVHLQILLTNNEA WKRFVTAAELPRDEADALYEALKKLRTYAAIEDE YVQQKDEQFREWFLKEFPQVKRKIQESIEKLRA LANGIEEVHRGCTISNVVSSSTGAASGIMSLAG LVLAPFTAGTSLALTAAGVGLGAASAVTGITTSI VEHSYTSSAEAEASRLTATSIDRLKVFKEVMRD ITPNLLSLLNNYYEATQTIGSEIRAIRQARARA RLPVTTWRISAGSGGQAERTIAGTTRAVSRGARI LSATTSGIFLALDVVNLVYESKHLHEGAKSASA EELRRQAQELEENLMELTQIYQRLNPCHTH*PQ TSAASRGGEPYTGHDKMQAFY*GDKEGKVKFMEL SVSDFGISVAEHSRGGVNADGKCTKEKAGMLEP GIREERGLESVGNRKKKFPLD*RIYWGEE*RGG VQEPAMRRPGKERAENAESRRVRTFGYSRRNSGS TTDLPPVRCPSKNEVFPW*WSPALSFQHPLCLV LLEVYLSQPVAS**WRWRWWL*CDGSPLGYLGV YVPCLNPEGQVMSHGHCPQLRTRCL*KPKHPGEY ARTYQEKQSHYSYTAGKETEN*LKSSLETGGGR ISRAILLSALCVSPNKLTYSP

Sequence NM_145641

ACTCTGGGGAAAGGAGGGTACAACCACATGTAAATTTTATTATAATGATGGTATAATGAACTTGGGGTGACCTGAGGGCATGTTTTTGTGTTACTGGGCA TGTGCCCCTTTAGGAGACTTCCACCTGTGCCTTACTTTCTCTTTCTTTGGGATGTGCTGGCCACAGACTTTACCAAAAACTCCATCCATTAGGATGGCAT TAGGACGGTTCTGGGGCTAAACTTAGGTGGGCCAGGGGCTGTTTCACTGTCAGCCTTTCTACTCTCTTTTCTTACCCACTCCTAGCTGCTAATGTCTATT TAACTACCTAATATTTCCCCCTTTAGAGAAAAAAAGCCAAATTTTTGGGTAGATCGGTGACAATTAATCTGGCTACTTCCTGCTGACAAGAGGCAGTGGT AATAATTGGGTTCTCTTTTTTGCTCTCTTGTAGCTGGTAGGTTGGGCAGAGAAAAGTGGTGGCCATCCAAGGGGCCCACGTAGATATCAGACATGGTTGA GACCTCGCGGTAACCTTGTGTAGAATCATTTGGAGTTTTATGGATTCTAGGTGGGAAGAAACAAAACAACCTTGTAAATCAAATGAGCATCGTTTGAAAG CTATAAGTTGTATAAAGCTGTTTTAGGACCAAGAAAGGGGGCTAACCAGGAAAACCAGGACCAGTTGTTAAATTTCCACCAGTCAAAGCCTCCTGAAACT CTGTTTTCCATTAACTTGTTGGCCCTGTCTGTAATTTTTTTAAGTTGGTTTGCACTTTACCTGATTGGTTGATGAAAACAGCAATGTTTATCAAGTGTTG CACAAGCTCCCCCTTGATTGGCTGTGAGCAAATTAAAAGCTCATCAATTTCATAAGACTATGCTTGCTAATGAAGCAATTTGTTCTGAAAGGGTATTGAC CTGGTTAGTTAGATTAATAATTTGTTGAGTAATTTTTAAGAAGAGTTTCTGGGCAGTAAAAATGGAGTTAAGGAGGTCCTCCAGTTCCCGTGCCAATACC AGCCAGAACGCCAATTATAGTCAGTGCTGTTAAAACTCCTCTTTCAGTTTTACCAGATTGAGCGTGTATAGGGAGGGGAATGCTATCGATAAGAGTGAGT TTGGGGATGATGTAAACTAGGGCCAAATCCCCGTTTAATTAGCAGACAAGCAGAGATATGCCTTGTTTCTATACAAAAATGTGATTTGTCATGTTAAGAC AAATATCAACAGTGATACTAAAGTAGGGTTTTTCCATGCTGTGTAAGTCTGCTTTAATACCCTCAGAAGTGGAAGTCAAGGCTAGTTCATGTAATGGGGG AACACAGGCAGTACTTGACAGAATGAAAGAGGAATCAAAAGCCCAATTAGAGGAAGGAGTGATGGGATCCCAACCAATATTGTGAAATTATGGGGAGCTG CAGTTTTTTGCAATGATTTTGCCCGAAGTTGTGAGACTGAAACCAGAAGTTGTTATGTTTAAAATGATATTCTGGTGTGGGTCTGGGGAAAAGGGTAGAT CCAGAATAGCTGGCTTCTTTCCACATAGTGGTTCTGTTGGGGGGCTTGGGAAATGAATAAAACACAAAGAAGAATTAGAATATCAGGTGAAGGTAGCAGG TGCTCCTGGCAGAAGAACCCACATAAGGAAGTGTCCAGAAGCCACACAGGGTATATCTCAGAGCCTGGAGAACGTGTCTGGTTATTATGCAGATGCACGG CTGGAGGTGGGATCCACACAGCTCAGAACAGCTGGATCTTGCTCACACTCTTTCAAGAGAAGCTTCCTTGAAAAGAAACGCTTTACTGAAGAGGCCACCA AATACTTCCGGGAGAGAGTCAGCCCAGTGCATCTGCAAATCCTGCTGACTAACAATGAAGCCTGGAAGAGATTCGTGACTGCGGCTGAATTGCCCAGGGA TGAGGCAGATGCTCTCTACGAAGCTCTGAAGAAGCTTAGAACATATGCAGCTATTGAGGACGAATATGTGCAGCAGAAAGATGAGCAGTTTAGGGAATGG TTTTTGAAAGAGTTTCCCCAAGTCAAGAGGAAGATCCAGGAGTCCATAGAAAAGCTTCGTGCCCTTGCAAATGGTATTGAAGAGGTCCACAGAGGCTGCA CCATCTCCAATGTGGTGTCCAGCTCCACTGGCGCTGCCTCTGGCATCATGTCCCTTGCTGGTCTTGTTTTGGCACCATTTACAGCAGGGACGAGTCTGGC CCTTACTGCAGCTGGGGTAGGGCTGGGAGCAGCGTCTGCTGTGACTGGGATCACCACCAGCATCGTGGAGCACTCATACACATCATCAGCAGAAGCTGAA GCCAGCAGGCTGACTGCAACCAGCATTGACCGATTGAAGGTATTTAAGGAAGTTATGCGTGACATCACACCCAACTTACTTTCCCTTCTTAATAATTATT ACGAAGCCACACAAACCATTGGGAGTGAAATCCGTGCCATCAGGCAAGCCAGAGCCAGGGCCCGACTCCCTGTGACCACCTGGCGAATCTCAGCTGGAAG TGGTGGTCAAGCAGAGAGAACGATTGCAGGCACCACCCGGGCAGTGAGCAGAGGAGCCCGGATCCTGAGTGCGACCACTTCAGGCATCTTCCTTGCACTG GATGTGGTCAACCTTGTATACGAGTCAAAGCACTTGCATGAGGGGGCAAAGTCTGCATCTGCTGAGGAGCTGAGGCGGCAGGCTCAGGAGCTGGAGGAGA ATCTAATGGAGCTCACTCAGATCTATCAGCGTCTGAATCCATGCCATACCCACTGACCCCAGACCAGTGCAGCCAGCAGGGGAGGTGAGCCATACACAGG CCACGACAAAATGCAGGCATTTTATTAGGGGGATAAAGAGGGCAAGGTAAAGTTTATGGAGCTGAGTGTTAGTGACTTTGGCATTTCTGTAGCTGAGCAC AGCAGGGGAGGGGTTAATGCAGATGGCAAGTGCACCAAGGAGAAGGCAGGAATGCTGGAGCCTGGAATAAGGGAGGAGAGGGGACTGGAGAGTGTGGGGA ATAGGAAGAAGAAATTTCCTTTAGACTAACGAATATATTGGGGGGAGGAATAGAGGGGAGGTGTGCAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAG AGCTGAAAATGCAGAAAGCCGAAGAGTTAGAACTTTTGGATACAGCAGAAGAAACAGCGGCTCCACTACCGACCTGCCCCCGGTTCGATGTCCTTCCAAG AATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCTGTCTTGTCCTCCTGGAAGTGTATCTCAGTCAGCCAGTGGCTTCTT GATGATGGCGGTGGAGGTGGTGGTTGTAGTGTGATGGATCCCCTTTAGGTTATTTAGGGGTATATGTCCCCTGCTTGAACCCTGAAGGCCAGGTAATGAG CCATGGCCATTGTCCCCAGCTGAGGACCAGGTGTCTCTAAAAACCCAAACATCCTGGAGAGTATGCGAGAACCTACCAAGAAAAACAGTCTCATTACTCA TATACAGCAGGCAAAGAGACAGAAAATTAACTGAAAAGCAGTTTAGAGACTGGGGGAGGCCGGATCTCTAGAGCCATCCTGCTGAGTGCCCTGTGTGTAA GTCCTAATAAACTCACCTACTCACCAA

refseq_APOL3.F1 (forward primer)
refseq_APOL3.R1 (reverse primer)
Single exon skipping

Frame 0

TLGKGGYNHM*ILL**WYNELGVT*GHVFVLLG MCPFRRLPPVPYFLFLWDVLATDFTKNSIH*DGI RTVLGLNLGGPGAVSLSAFLLSFLTHS*LLMSI *LPNISPFREKKPNFWVDR*QLIWLLPADKRQW **LGSLFCSLVAGRLGREKWWPSKGPT*ISDMVE TSR*PCVESFGVLWILGGKKQNNLVNQMSIV*K L*VV*SCFRTKKGG*PGKPGPVVKFPPVKAS*N SVFH*LVGPVCNFFKLVCTLPDWLMKTAMFIKCC TSSPLIGCEQIKSSSIS*DYAC**SNLF*KGID LVS*INNLLSNF*EEFLGSKNGVKEVLQFPCQY QPERQL*SVLLKLLFQFYQIERV*GGECYR*E*V WG*CKLGPNPRLISRQAEICLVSIQKCDLSC*D KYQQ*Y*SRVFPCCVSLL*YPQKWKSRLVHVMG EHRQYLTE*KRNQKPN*RKE*WDPNQYCEIMGSC SFLQ*FCPKL*D*NQKLLCLK*YSGVGLGKRVD PE*LASFHIVVLLGGLGNE*NTKKN*NIR*R*Q VLLAEEPT*GSVQKPHRVYLRAWRTCLVIMQMHG WRWDPHSSEQLDLAHTLSREASLKRNALLKRPP NTSGRESAQCICKSC*LTMKPGRDS*LRLNCPG MRQMLSTKL*RSLEHMQLLRTNMCSRKMSSLGNG F*KSFPKSRGRSRSP*KSFVPLQMVLKRSTEAA PSPMWCPAPLALPLASCPLLVLFWHHLQQGRVW PLLQLG*GWEQRLL*LGSPPASWSTHTHHQQKLK PAG*LQPALTD*RYLRKLCVTSHPTYFPFLIII TKPHKPLGVKSVPSGKPEPGPDSL*PPGESQLE VVVKQRERLQAPPGQ*AEEPGS*VRPLQASSLHW MWSTLYTSQSTCMRGQSLHLLRS*GGRLRSWRR I*WSSLRSISV*IHAIPTDPRPVQPAGEVSHTQ ATTKCRHFIRGIKRAR*SLWS*VLVTLAFL*LST AGEGLMQMASAPRRRQECWSLE*GRRGDWRVWG IGRRNFL*TNEYIGGRNRGEVCRNQQ*EGQEKK ELKMQKAEELELLDTAEETAAPLPTCPRFDVLPR MKSFPGDGPLPCLSSIHSVLSSWKCISVSQWLL DDGGGGGGCSVMDPL*VI*GYMSPA*TLKAR** AMAIVPS*GPGVSKNPNILESMREPTKKNSLITH IQQAKRQKIN*KAV*RLGEAGSLEPSC*VPCV* VLINSPTHQ

Frame 1

LWGKEGTTTCKFYYNDGIMNLG*PEGMFLCYWA CAPLGDFHLCLTFSFFGMCWPQTLPKTPSIRMA LGRFWG*T*VGQGLFHCQPFYSLFLPTPSC*CLF NYLIFPPLEKKSQIFG*IGDN*SGYFLLTRGSG NNWVLFFALL*LVGWAEKSGGHPRGPRRYQTWL RPRGNLV*NHLEFYGF*VGRNKTTL*IK*ASFES YKLYKAVLGPRKGANQENQDQLLNFHQSKPPET LFSINLLALSVIFLSWFALYLIG**KQQCLSSV AQAPP*LAVSKLKAHQFHKTMLANEAICSERVLT WLVRLIIC*VIFKKSFWAVKMELRRSSSSRANT SQNANYSQCC*NSSFSFTRLSVYREGNAIDKSE FGDDVN*GQIPV*LADKQRYALFLYKNVICHVKT NINSDTKVGFFHAV*VCFNTLRSGSQG*FM*WG NTGST*QNERGIKSPIRGRSDGIPTNIVKLWGA AVFCNDFARSCETETRSCYV*NDILVWVWGKG*I QNSWLLST*WFCWGAWEMNKTQRRIRISGEGSR CSWQKNPHKEVSRSHTGYISEPGERVWLLCRCT AGGGIHTAQNSWILLTLFQEKLP*KETLY*RGHQ ILPGESQPSASANPAD*Q*SLEEIRDCG*IAQG *GRCSLRSSEEA*NICSY*GRICAAER*AV*GM VFERVSPSQEEDPGVHRKASCPCKWY*RGPQRLH HLQCGVQLHWRCLWHHVPCWSCFGTIYSRDESG PYCSWGRAGSSVCCDWDHHQHRGALIHIISRS* SQQADCNQH*PIEGI*GSYA*HHTQLTFPS**LL RSHTNHWE*NPCHQASQSQGPTPCDHLANLSWK WWSSRENDCRHHPGSEQRSPDPECDHFRHLPCT GCGQPCIRVKALA*GGKVCIC*GAEAAGSGAGGE SNGAHSDLSASESMPYPLTPDQCSQQGR*AIHR PRQNAGILLGG*RGQGKVYGAEC**LWHFCS*A QQGRG*CRWQVHQGEGRNAGAWNKGGEGTGECGE *EEEISFRLTNILGGGIEGRCAGTSNEKARKRK S*KCRKPKS*NFWIQQKKQRLHYRPAPGSMSFQ E*SLSLVMVPCPVFPASTLSCPPGSVSQSASGFL MMAVEVVVVV*WIPFRLFRGICPLLEP*RPGNE PWPLSPAEDQVSLKTQTSWRVCENLPRKTVSLL IYSRQRDRKLTEKQFRDWGRPDL*SHPAECPVCK S**THLLT

Frame 2

SGERRVQPHVNFIIMMV**TWGDLRACFCVTGH VPL*ETSTCALLSLSLGCAGHRLYQKLHPLGWH *DGSGAKLRWARGCFTVSLSTLFSYPLLAANVY LTT*YFPL*RKKAKFLGRSVTINLATSC*QEAVV IIGFSFLLSCSW*VGQRKVVAIQGAHVDIRHG* DLAVTLCRIIWSFMDSRWEETKQPCKSNEHRLK AISCIKLF*DQERGLTRKTRTSC*ISTSQSLLKL CFPLTCWPCL*FF*VGLHFT*LVDENSNVYQVL HKLPLDWL*AN*KLINFIRLCLLMKQFVLKGY* PG*LD**FVE*FLRRVSGQ*KWS*GGPPVPVPIP ARTPIIVSAVKTPLSVLPD*ACIGRGMLSIRVS LGMM*TRAKSPFN*QTSRDMPCFYTKM*FVMLR QISTVILK*GFSMLCKSALIPSEVEVKASSCNGG TQAVLDRMKEESKAQLEEGVMGSQPIL*NYGEL QFFAMILPEVVRLKPEVVMFKMIFWCGSGEKGR SRIAGFFPHSGSVGGLGK*IKHKEELEYQVKVAG APGRRTHIRKCPEATQGISQSLENVSGYYADAR LEVGSTQLRTAGSCSHSFKRSFLEKKRFTEEAT KYFRERVSPVHLQILLTNNEAWKRFVTAAELPRD EADALYEALKKLRTYAAIEDEYVQQKDEQFREW FLKEFPQVKRKIQESIEKLRALANGIEEVHRGC TISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLA LTAAGVGLGAASAVTGITTSIVEHSYTSSAEAE ASRLTATSIDRLKVFKEVMRDITPNLLSLLNNY YEATQTIGSEIRAIRQARARARLPVTTWRISAGS GGQAERTIAGTTRAVSRGARILSATTSGIFLAL DVVNLVYESKHLHEGAKSASAEELRRQAQELEE NLMELTQIYQRLNPCHTH*PQTSAASRGGEPYTG HDKMQAFY*GDKEGKVKFMELSVSDFGISVAEH SRGGVNADGKCTKEKAGMLEPGIREERGLESVG NRKKKFPLD*RIYWGEE*RGGVQEPAMRRPGKER AENAESRRVRTFGYSRRNSGSTTDLPPVRCPSK NEVFPW*WSPALSFQHPLCLVLLEVYLSQPVAS **WRWRWWL*CDGSPLGYLGVYVPCLNPEGQVMS HGHCPQLRTRCL*KPKHPGEYARTYQEKQSHYS YTAGKETEN*LKSSLETGGGRISRAILLSALCV SPNKLTYSP