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Sequences

Sequence NM_183360

GGGCGCGCGCCCGCCCATCCGCCCTCCGCCCTCCGCCCTCGCGCCCTCGCGCCGGGGGCGGGCGCTGCGCGTGCCGGGCGGAGAAGCGGCGCGAGCCGGG CGCTGCGAACGTTCGCCGCGGGGGTGGCTCCGGGGCCTGAGTAGGCGCTGCCGCTGCCTCAGCCGAGGGGGCTGGGCCGGAGCGTGCGGAGGAGTGAGGC CGCAGGAGACCTTCCCGACGACCCCTGCTCCGGCGGGGAAGTGAGCAAGGATGATTGAGGAAAGTGGGAACAAGCGGAAGACCATGGCAGAGAAGAGGCA GCTGTTCATAGAAATGCGTGCTCAGAATTTTGATGTCATACGACTATCAACTTACAGAACAGCCTGCAAATTACGATTTGTACAAAAACGATGCAACCTT CATCTTGTTGATATCTGGAACATGATTGAAGCCTTCCGAGACAATGGCCTTAATACACTGGACCATACCACCGAGATCAGTGTGTCCCGCCTCGAAACTG TCATCTCCTCCATCTACTATCAGTTGAACAAGCGCCTTCCTTCTACTCACCAAATTAGTGTGGAACAATCTATCAGCCTCCTCCTCAACTTTATGATTGC TGCATATGACAGTGAGGGCCGAGGCAAGTTGACGGTATTTTCAGTTAAAGCTATGTTAGCAACCATGTGTGGTGGAAAAATGCTGGACAAATTGAGATAT GTTTTCTCCCAGATGTCAGATTCCAATGGCTTAATGATATTTAGCAAGTTTGACCAGTTTCTGAAGGAAGTTCTGAAGCTCCCAACAGCTGTCTTTGAAG GGCCATCTTTTGGTTACACAGAGCACTCAGTCCGCACCTGTTTTCCACAGCAGAGAAAGATAATGCTAAATATGTTTTTAGACACAATGATGGCTGACCC TCCTCCCCAGTGCCTTGTCTGGCTACCTCTCATGCACAGGCTTGCCCATGTTGAGAATGTCTTCCATCCCGTGGAGTGCTCCTACTGCCGATGTGAGAGT ATGATGGGTTTCCGGTACCGATGCCAGCAGTGCCACAACTATCAGCTCTGCCAGAATTGCTTTTGGCGTGGCCATGCCGGCGGCCCTCACAGCAACCAGC ACCAGATGAAGGAGCATTCCTCTTGGAAATCTCCTGCAAAGAAGCTGAGCCATGCAATTAGTAAATCTTTGGGGTGTGTACCCACGAGAGAACCCCCGCA TCCTGTTTTTCCTGAGCAACCAGAGAAACCACTTGACCTTGCACATATAGTTCCTCCTCGCCCTCTGACTAATATGAATGACACCATGGTTAGCCACATG TCCTCTGGAGTGCCCACTCCCACCAAGAGGTTACAGTATAGCCAGGATATACCCAGTCACTTGGCCGATGAGCATGCGCTGATAGCCTCCTATGTGGCCC GTCTGCAGCACTGTGCACGTGTTCTGGACAGTCCTAGCCGACTGGATGAGGAACACCGTCTTATAGCTCGCTATGCTGCCCGGCTGGCTGCAGAAGCAGG AAACGTGACTCGTCCTCCCACTGACTTGAGCTTTAACTTTGATGCCAACAAACAACAAAGACAGCTTATTGCAGAACTGGAAAACAAAAACAGAGAGATC CTGCAGGAGATTCAGCGTCTCCGCCTGGAACACGAGCAGGCCTCCCAGCCCACCCCTGAGAAGGCACAGCAGAACCCCACGCTGCTGGCAGAGCTGCGGC TGCTGAGGCAAAGGAAGGATGAACTGGAGCAGAGGATGTCGGCCCTGCAGGAGAGCAGGCGGGAGCTGATGGTCCAGCTGGAAGAGCTGATGAAGTTGCT GAAGGAGGAAGAGCAAAAGCAGGCAGCTCAGGCCACAGGGTCACCACATACATCGCCCACCCATGGAGGCGGCCGGCCAATGCCCATGCCAGTGCGCTCC ACGTCTGCCGGCTCCACCCCCACCCACTGTCCGCAGGACTCGCTGAGCGGAGTCGGGGGAGACGTGCAGGAGGCCTTCGCACAAGGTACGAGGAGAAACC TCCGCAATGACCTGCTGGTGGCAGCTGACTCCATCACCAACACCATGTCATCCCTGGTGAAGGAGCTCCATTCAGGTTAGCAGAGGAGCCGGACACAGAG GAAGCTCAGGCACAGAGGACGAGGAGCAAGCTGGCGCCGACATGGCGAAGGCAAGGTCTTCCCCCAGAGGCACATTCCTCTCCATCTTTCCACCGCACAC CTGGACCAGGCTTGCAGGCTGCCAGACGTCACTCCACCCGCCAGGGAGAGGGGAGCCAGAGCCGGTGGGAAGCGGGGAGGGGCTGCGTGGCACAGCTAGT GGGCCTCCCCCTGCACAGCCCTGCATGTACTAGCACCTTCATCACTCCCCTCAGGGCATGGTCTCATCTCCGCATCAGGAATTCACCTGGAGGTTGAAAA GAGAAAAGAAAAAGCACCAA

refseq_DTNB.F5 (forward primer)
refseq_DTNB.R5 (reverse primer)
Single exon skipping

Frame 0

GRAPAHPPSALRPRALAPGAGAARAGRRSGASR ALRTFAAGVAPGPE*ALPLPQPRGLGRSVRRSEA AGDLPDDPCSGGEVSKDD*GKWEQAEDHGREEA AVHRNACSEF*CHTTINLQNSLQITICTKTMQP SSC*YLEHD*SLPRQWP*YTGPYHRDQCVPPRNC HLLHLLSVEQAPSFYSPN*CGTIYQPPPQLYDC CI*Q*GPRQVDGIFS*SYVSNHVWWKNAGQIEI CFLPDVRFQWLNDI*QV*PVSEGSSEAPNSCL*R AIFWLHRALSPHLFSTAEKDNAKYVFRHNDG*P SSPVPCLATSHAQACPC*ECLPSRGVLLLPM*E YDGFPVPMPAVPQLSALPELLLAWPCRRPSQQPA PDEGAFLLEISCKEAEPCN**IFGVCTHERTPA SCFS*ATRETT*PCTYSSSSPSD*YE*HHG*PH VLWSAHSHQEVTV*PGYTQSLGR*ACADSLLCGP SAALCTCSGQS*PTG*GTPSYSSLCCPAGCRSR KRDSSSH*LEL*L*CQQTTKTAYCRTGKQKQRD PAGDSASPPGTRAGLPAHP*EGTAEPHAAGRAAA AEAKEG*TGAEDVGPAGEQAGADGPAGRADEVA EGGRAKAGSSGHRVTTYIAHPWRRPANAHASAL HVCRLHPHPLSAGLAERSRGRRAGGLRTRYEEKP PQ*PAGGS*LHHQHHVIPGEGAPFRLAEEPDTE EAQAQRTRSKLAPTWRRQGLPPEAHSSPSFHRT PGPGLQAARRHSTRQGEGSQSRWEAGRGCVAQLV GLPLHSPACTSTFITPLRAWSHLRIRNSPGG*K EKRKST

Frame 1

GARPPIRPPPSALAPSRRGRALRVPGGEAARAG RCERSPRGWLRGLSRRCRCLSRGGWAGACGGVR PQETFPTTPAPAGK*ARMIEESGNKRKTMAEKRQ LFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNL HLVDIWNMIEAFRDNGLNTLDHTTEISVSRLET VISSIYYQLNKRLPSTHQISVEQSISLLLNFMIA AYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRY VFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFE GPSFGYTEHSVRTCFPQQRKIMLNMFLDTMMADP PPQCLVWLPLMHRLAHVENVFHPVECSYCRCES MMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQ HQMKEHSSWKSPAKKLSHAISKSLGCVPTREPPH PVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHM SSGVPTPTKRLQYSQDIPSHLADEHALIASYVA RLQHCARVLDSPSRLDEEHRLIARYAARLAAEAG NVTRPPTDLSFNFDANKQQRQLIAELENKNREI LQEIQRLRLEHEQASQPTPEKAQQNPTLLAELR LLRQRKDELEQRMSALQESRRELMVQLEELMKLL KEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRS TSAGSTPTHCPQDSLSGVGGDVQEAFAQGTRRN LRNDLLVAADSITNTMSSLVKELHSG*QRSRTQR KLRHRGRGASWRRHGEGKVFPQRHIPLHLSTAH LDQACRLPDVTPPARERGARAGGKRGGAAWHS* WASPCTALHVLAPSSLPSGHGLISASGIHLEVEK RKEKAP

Frame 2

ARARPSALRPPPSRPRAGGGRCACRAEKRREPG AANVRRGGGSGA*VGAAAASAEGAGPERAEE*G RRRPSRRPLLRRGSEQG*LRKVGTSGRPWQRRG SCS*KCVLRILMSYDYQLTEQPANYDLYKNDATF ILLISGT*LKPSETMALIHWTIPPRSVCPASKL SSPPSTIS*TSAFLLLTKLVWNNLSASSSTL*L LHMTVRAEAS*RYFQLKLC*QPCVVEKCWTN*DM FSPRCQIPMA**YLASLTSF*RKF*SSQQLSLK GHLLVTQSTQSAPVFHSRER*C*ICF*TQ*WLT LLPSALSGYLSCTGLPMLRMSSIPWSAPTADVRV *WVSGTDASSATTISSARIAFGVAMPAALTATS TR*RSIPLGNLLQRS*AMQLVNLWGVYPRENPR ILFFLSNQRNHLTLHI*FLLAL*LI*MTPWLATC PLECPLPPRGYSIARIYPVTWPMSMR**PPMWP VCSTVHVFWTVLADWMRNTVL*LAMLPGWLQKQ ET*LVLPLT*ALTLMPTNNKDSLLQNWKTKTERS CRRFSVSAWNTSRPPSPPLRRHSRTPRCWQSCG C*GKGRMNWSRGCRPCRRAGGS*WSSWKS**SC *RRKSKSRQLRPQGHHIHRPPMEAAGQCPCQCAP RLPAPPPPTVRRTR*AESGETCRRPSHKVRGET SAMTCWWQLTPSPTPCHPW*RSSIQVSRGAGHR GSSGTEDEEQAGADMAKARSSPRGTFLSIFPPHT WTRLAGCQTSLHPPGRGEPEPVGSGEGLRGTAS GPPPAQPCMY*HLHHSPQGMVSSPHQEFTWRLK REKKKHQ

Sequence NM_021907

GGGCGCGCGCCCGCCCATCCGCCCTCCGCCCTCCGCCCTCGCGCCCTCGCGCCGGGGGCGGGCGCTGCGCGTGCCGGGCGGAGAAGCGGCGCGAGCCGGG CGCTGCGAACGTTCGCCGCGGGGGTGGCTCCGGGGCCTGAGTAGGCGCTGCCGCTGCCTCAGCCGAGGGGGCTGGGCCGGAGCGTGCGGAGGAGTGAGGC CGCAGGAGACCTTCCCGACGACCCCTGCTCCGGCGGGGAAGTGAGCAAGGATGATTGAGGAAAGTGGGAACAAGCGGAAGACCATGGCAGAGAAGAGGCA GCTGTTCATAGAAATGCGTGCTCAGAATTTTGATGTCATACGACTATCAACTTACAGAACAGCCTGCAAATTACGATTTGTACAAAAACGATGCAACCTT CATCTTGTTGATATCTGGAACATGATTGAAGCCTTCCGAGACAATGGCCTTAATACACTGGACCATACCACCGAGATCAGTGTGTCCCGCCTCGAAACTG TCATCTCCTCCATCTACTATCAGTTGAACAAGCGCCTTCCTTCTACTCACCAAATTAGTGTGGAACAATCTATCAGCCTCCTCCTCAACTTTATGATTGC TGCATATGACAGTGAGGGCCGAGGCAAGTTGACGGTATTTTCAGTTAAAGCTATGTTAGCAACCATGTGTGGTGGAAAAATGCTGGACAAATTGAGATAT GTTTTCTCCCAGATGTCAGATTCCAATGGCTTAATGATATTTAGCAAGTTTGACCAGTTTCTGAAGGAAGTTCTGAAGCTCCCAACAGCTGTCTTTGAAG GGCCATCTTTTGGTTACACAGAGCACTCAGTCCGCACCTGTTTTCCACAGCAGAGAAAGATAATGCTAAATATGTTTTTAGACACAATGATGGCTGACCC TCCTCCCCAGTGCCTTGTCTGGCTACCTCTCATGCACAGGCTTGCCCATGTTGAGAATGTCTTCCATCCCGTGGAGTGCTCCTACTGCCGATGTGAGAGT ATGATGGGTTTCCGGTACCGATGCCAGCAGTGCCACAACTATCAGCTCTGCCAGAATTGCTTTTGGCGTGGCCATGCCGGCGGCCCTCACAGCAACCAGC ACCAGATGAAGGAGCATTCCTCTTGGAAATCTCCTGCAAAGAAGCTGAGCCATGCAATTAGTAAATCTTTGGGGTGTGTACCCACGAGAGAACCCCCGCA TCCTGTTTTTCCTGAGCAACCAGAGAAACCACTTGACCTTGCACATATAGTTCCTCCTCGCCCTCTGACTAATATGAATGACACCATGGTTAGCCACATG TCCTCTGGAGTGCCCACTCCCACCAAGAGGTTACAGTATAGCCAGGATATACCCAGTCACTTGGCCGATGAGCATGCGCTGATAGCCTCCTATGTGGCCC GTCTGCAGCACTGTGCACGTGTTCTGGACAGTCCTAGCCGACTGGATGAGGAACACCGTCTTATAGCTCGCTATGCTGCCCGGCTGGCTGCAGAAGCAGG AAACGTGACTCGTCCTCCCACTGACTTGAGCTTTAACTTTGATGCCAACAAACAACAAAGACAGCTTATTGCAGAACTGGAAAACAAAAACAGAGAGATC CTGCAGGAGATTCAGCGTCTCCGCCTGGAACACGAGCAGGCCTCCCAGCCCACCCCTGAGAAGGCACAGCAGAACCCCACGCTGCTGGCAGAGCTGCGGC TGCTGAGGCAAAGGAAGGATGAACTGGAGCAGAGGATGTCGGCCCTGCAGGAGAGCAGGCGGGAGCTGATGGTCCAGCTGGAAGAGCTGATGAAGTTGCT GAAGGAGGAAGAGCAAAAGCAGGCAGCTCAGGCCACAGGGTCACCACATACATCGCCCACCCATGGAGGCGGCCGGCCAATGCCCATGCCAGTGCGCTCC ACGTCTGCCGGCTCCACCCCCACCCACTGTCCGCAGGACTCGCTGAGCGGAGTCGGGGGAGACGTGCAGGAGGCCTTCGCACAAGGTACGAGGAGAAACC TCCGCAATGACCTGCTGGTGGCAGCTGACTCCATCACCAACACCATGTCATCCCTGGTGAAGGAGCTCCATTCAGCAGAGGAAGGTGCAGAGGAAGAAGA AGAGAAGATGCAGAATGGGAAAGACAGAGGTTAGCAGAGGAGCCGGACACAGAGGAAGCTCAGGCACAGAGGACGAGGAGCAAGCTGGCGCCGACATGGC GAAGGCAAGGTCTTCCCCCAGAGGCACATTCCTCTCCATCTTTCCACCGCACACCTGGACCAGGCTTGCAGGCTGCCAGACGTCACTCCACCCGCCAGGG AGAGGGGAGCCAGAGCCGGTGGGAAGCGGGGAGGGGCTGCGTGGCACAGCTAGTGGGCCTCCCCCTGCACAGCCCTGCATGTACTAGCACCTTCATCACT CCCCTCAGGGCATGGTCTCATCTCCGCATCAGGAATTCACCTGGAGGTTGAAAAGAGAAAAGAAAAAGCACCAA

refseq_DTNB.F5 (forward primer)
refseq_DTNB.R5 (reverse primer)
Single exon skipping

Frame 0

GRAPAHPPSALRPRALAPGAGAARAGRRSGASR ALRTFAAGVAPGPE*ALPLPQPRGLGRSVRRSEA AGDLPDDPCSGGEVSKDD*GKWEQAEDHGREEA AVHRNACSEF*CHTTINLQNSLQITICTKTMQP SSC*YLEHD*SLPRQWP*YTGPYHRDQCVPPRNC HLLHLLSVEQAPSFYSPN*CGTIYQPPPQLYDC CI*Q*GPRQVDGIFS*SYVSNHVWWKNAGQIEI CFLPDVRFQWLNDI*QV*PVSEGSSEAPNSCL*R AIFWLHRALSPHLFSTAEKDNAKYVFRHNDG*P SSPVPCLATSHAQACPC*ECLPSRGVLLLPM*E YDGFPVPMPAVPQLSALPELLLAWPCRRPSQQPA PDEGAFLLEISCKEAEPCN**IFGVCTHERTPA SCFS*ATRETT*PCTYSSSSPSD*YE*HHG*PH VLWSAHSHQEVTV*PGYTQSLGR*ACADSLLCGP SAALCTCSGQS*PTG*GTPSYSSLCCPAGCRSR KRDSSSH*LEL*L*CQQTTKTAYCRTGKQKQRD PAGDSASPPGTRAGLPAHP*EGTAEPHAAGRAAA AEAKEG*TGAEDVGPAGEQAGADGPAGRADEVA EGGRAKAGSSGHRVTTYIAHPWRRPANAHASAL HVCRLHPHPLSAGLAERSRGRRAGGLRTRYEEKP PQ*PAGGS*LHHQHHVIPGEGAPFSRGRCRGRR REDAEWERQRLAEEPDTEEAQAQRTRSKLAPTW RRQGLPPEAHSSPSFHRTPGPGLQAARRHSTRQG EGSQSRWEAGRGCVAQLVGLPLHSPACTSTFIT PLRAWSHLRIRNSPGG*KEKRKST

Frame 1

GARPPIRPPPSALAPSRRGRALRVPGGEAARAG RCERSPRGWLRGLSRRCRCLSRGGWAGACGGVR PQETFPTTPAPAGK*ARMIEESGNKRKTMAEKRQ LFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNL HLVDIWNMIEAFRDNGLNTLDHTTEISVSRLET VISSIYYQLNKRLPSTHQISVEQSISLLLNFMIA AYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRY VFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFE GPSFGYTEHSVRTCFPQQRKIMLNMFLDTMMADP PPQCLVWLPLMHRLAHVENVFHPVECSYCRCES MMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQ HQMKEHSSWKSPAKKLSHAISKSLGCVPTREPPH PVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHM SSGVPTPTKRLQYSQDIPSHLADEHALIASYVA RLQHCARVLDSPSRLDEEHRLIARYAARLAAEAG NVTRPPTDLSFNFDANKQQRQLIAELENKNREI LQEIQRLRLEHEQASQPTPEKAQQNPTLLAELR LLRQRKDELEQRMSALQESRRELMVQLEELMKLL KEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRS TSAGSTPTHCPQDSLSGVGGDVQEAFAQGTRRN LRNDLLVAADSITNTMSSLVKELHSAEEGAEEEE EKMQNGKDRG*QRSRTQRKLRHRGRGASWRRHG EGKVFPQRHIPLHLSTAHLDQACRLPDVTPPAR ERGARAGGKRGGAAWHS*WASPCTALHVLAPSSL PSGHGLISASGIHLEVEKRKEKAP

Frame 2

ARARPSALRPPPSRPRAGGGRCACRAEKRREPG AANVRRGGGSGA*VGAAAASAEGAGPERAEE*G RRRPSRRPLLRRGSEQG*LRKVGTSGRPWQRRG SCS*KCVLRILMSYDYQLTEQPANYDLYKNDATF ILLISGT*LKPSETMALIHWTIPPRSVCPASKL SSPPSTIS*TSAFLLLTKLVWNNLSASSSTL*L LHMTVRAEAS*RYFQLKLC*QPCVVEKCWTN*DM FSPRCQIPMA**YLASLTSF*RKF*SSQQLSLK GHLLVTQSTQSAPVFHSRER*C*ICF*TQ*WLT LLPSALSGYLSCTGLPMLRMSSIPWSAPTADVRV *WVSGTDASSATTISSARIAFGVAMPAALTATS TR*RSIPLGNLLQRS*AMQLVNLWGVYPRENPR ILFFLSNQRNHLTLHI*FLLAL*LI*MTPWLATC PLECPLPPRGYSIARIYPVTWPMSMR**PPMWP VCSTVHVFWTVLADWMRNTVL*LAMLPGWLQKQ ET*LVLPLT*ALTLMPTNNKDSLLQNWKTKTERS CRRFSVSAWNTSRPPSPPLRRHSRTPRCWQSCG C*GKGRMNWSRGCRPCRRAGGS*WSSWKS**SC *RRKSKSRQLRPQGHHIHRPPMEAAGQCPCQCAP RLPAPPPPTVRRTR*AESGETCRRPSHKVRGET SAMTCWWQLTPSPTPCHPW*RSSIQQRKVQRKK KRRCRMGKTEVSRGAGHRGSSGTEDEEQAGADMA KARSSPRGTFLSIFPPHTWTRLAGCQTSLHPPG RGEPEPVGSGEGLRGTASGPPPAQPCMY*HLHH SPQGMVSSPHQEFTWRLKREKKKHQ