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Sequences

Sequence NM_031372

GTCATCTGGCCAGCCCCCGCCCCTCCTCCCGGCGTCAGCCCGCCAGAGGCCGCGCGGGGCCCGGGCTTCGGCCGATCAGCCCGGGAGGCCCCGCCGCGCC CCCTTGGCCCGCGCGCCCGTGGTCACAGTGGAAGAGGCGCCCGCGCTGCGCTGCCCGGAGGAGCCGTCGCGCGCCCGCTTCCTGTTCGGCTGGTTCCTGC CAGCTCGAGGACAAAACACGCGTGCGCGCGGCGGGCGAGCGCGCTCGCCGCCTCAGTCGCCAGCGCCGGGCGCAGTCCGCCTTTTTCCGGAGCAGACTGG CCGCGGTGCTAGTCGGTAGCAGCGGCCGCCGCAGCGGCTCCGCACTGGCGAACCGAGGGCAGAAAAAGGCGGGGTTGACGGCTTTTTGGTAGGAGTGGGC TGGACCGGACGCCAGAGACAAAGGCTCCCAAGGCAAGAGGGACTGTGGCCCTGCGTCGGCTCTGCTCGGGACTGCTGACCCCAGGAATTTACGCCCCTTC GTTTTTCTCTTCTGATTCTTCTCTTCTCCCAAGCCCGCGTCCCCTCACGCGTGGCCTCTCTCCTTGCCGGGAGGGCCGCGATGGAGGTCCCGCCCAGGCT TTCCCATGTGCCGCCGCCATTGTTCCCCTCCGCTCCCGCTACTTTAGCCTCCCGCAGCCTCTCCCATTGGCGGCCGCGGCCGCCGCGGCAGCTAGCCCCG CTCCTCCCTTCGCTCGCTCCCAGCTCCGCCCGGCAGGGGGCGCGCCGGGCCCAGCGCCACGTCACCGCCCAGCAGCCCTCCCGATTGGCGGGCGGGGCGG CTATAAAGGGAGGGCGCAGGCGGCGCCCGGATCTCTTCCGCCGCCATTTTAAATCCAGCTCCATACAACGCTCCGCCGCCGCTGCTGCCGCGACCCGGAC TGCGCGCCAGCACCCCCCTGCCGACAGCTCCGTCACTATGGAGGATATGAACGAGTACAGCAATATAGAGGAATTCGCAGAGGGATCCAAGATCAACGCG AGCAAGAATCAGCAGGATGACGGTAAAATGTTTATTGGAGGCTTGAGCTGGGATACAAGCAAAAAAGATCTGACAGAGTACTTGTCTCGATTTGGGGAAG TTGTAGACTGCACAATTAAAACAGATCCAGTCACTGGGAGATCAAGAGGATTTGGATTTGTGCTTTTCAAAGATGCTGCTAGTGTTGATAAGGTTTTGGA ACTGAAAGAACACAAACTGGATGGCAAATTGATAGATCCCAAAAGGGCCAAAGCTTTAAAAGGGAAAGAACCTCCCAAAAAGGTTTTTGTGGGTGGATTG AGCCCGGATACTTCTGAAGAACAAATTAAAGAATATTTTGGAGCCTTTGGAGAGATTGAAAATATTGAACTTCCCATGGATACAAAAACAAATGAAAGAA GAGGATTTTGTTTTATCACATATACTGATGAAGAGCCAGTAAAAAAATTGTTAGAAAGCAGATACCATCAAATTGGTTCTGGGAAGTGTGAAATCAAAGT TGCACAACCCAAAGAGGTATATAGGCAGCAACAGCAACAACAAAAAGGTGGAAGAGGTGCTGCAGCTGGTGGACGAGGTGGTACGAGGGGTCGTGGCCGA GGTCAGGGCCAAAACTGGAACCAAGGATTTAATAACTATTATGATCAAGGATATGGAAATTACAATAGTGCCTATGGTGGTGATCAAAACTATAGTGGCT ATGGCGGATATGATTATACTGGGTATAACTATGGGAACTATGGATATGGACAGGGATATGCAGACTACAGTGGCCAACAGAGCACTTATGGCAAGGCATC TCGAGGGGGTGGCAATCACCAAAACAATTACCAGCCATACTAAAGGAGAACATTGGAGAAAACAGGAGGAGATGTTAAAGTAACCCATCTTGCAGGACGA CATTGAAGATTGGTCTTCTGTTGATCTAAGATGATTATTTTGTAAAAGACTTTCTAGTGTACAAGACACCATTGTGTCCAACTGTATATAGCTGCCAATT AGTTTTCTTTGTTTTTACTTTGTCCTTTGCTATCTGTGTTATGACTCAATGTGGATTTGTTTATACACATTTTATTTGTATCATTTCATGTTAAACCTCA AATAAATGCTTCCTTATGTGATTGCTTTTCTGCGTCAGGTACTACATAGCTCTGTAAAAAATGTAATTTAAAATAAGCAATAATTAAGGCACAGTTGATT TTGTAGAGTATTGGTCCATACAGAGAAACTGTGGTCCTTTATAAATAGCCAGCCAGCGTCACCCTCTTCTCCAATTTGTAGGTGTATTTTATGCTCTTAA GGCTTCATCTTCTCCCTGTAACTGAGATTTCTACCACACCTTTGAACAATGTTCTTTCCCTTCTGGTTATCTGAAGACTGTCCTGAAAGGAAGACATAAG TGTTGTGATTAGTAGAAGCTTTGTAATCATAACACAATGAGTAATTCTTGATAAAAGTTCAGATACAAAAGGAGCACTGTAAAACTGGTAGGAGCTATGG TTTAAGAGCATTGGAAGTAGTTACAACTCAAGGATTTTGGTAGAAAGGTATGAGTTTGGTCGAAAAATTAAAATAGTGGCAAAATAAGATTTAGTTGTGT TTTCTCAGAGCCGCCACAAGATTGAACAAAATGTTTTCTGTTTGGGCATCCTGAGGAAGTTGTATTAGCTGTTAATGCTCTGTGAGTTTAGAAAAAGTCT TGATAGTAAATCTAGTTTTTGACACAGTGCATGAACTAAGTAGTTAAATATTTACATATTCAGAAAGGAATAGTGGAAAAGGTATCTTGGTTATGACAAA GTCATTACAAATGTGACTAAGTCATTACAAATGTGACTGAGTCATTACAGTGGACCCTCTGGGTGCATTGAAAAGAATCCGTTTTATATCCAGGTTTCAG AGGACCTGGAATAATAAAAAGCTTTGGATTTTGCATTCAGTGTAGTTGGATTTTGGGACCTTGGCCTCAGTGTTATTTACTGGGATTGGCATACGTGTTC ACAGGCAGAGTAGTTGATCTCACACAACGGGTGATCTCACAAAACTGGTAAGTTTCTTATGCTCATGAGCCCTCCCTTTTTTTTTTTAATTTGGTGCCTG CAACTTTCTTAACAATGATTCTACTTCCTGGGCTATCACATTATAATGCTCTTGGCCTCTTTTTTGCTGCTGTTTTGCTATTCTTAAACTTAGGCCAAGT ACCAATGTTGGCTGTTAGAAGGGATTCTGTTCATTCAACATGCAACTTTAGGGAATGGAAGTAAGTTCATTTTTAAGTTGTGTTGTCAGTAGGTGCGGTG TCTAGGGTAGTGAATCCTGTAAGTTCAAATTTATGATTAGGTGACGAGTTGACATTGAGATTGTCCTTTTCCCTGATCAAAAAATGAATAAAGCCTTTTT AAAC

refseq_HNRPDL.F1 (forward primer)
refseq_HNRPDL.R1 (reverse primer)
Single exon skipping

Frame 0

VIWPAPAPPPGVSPPEAARGPGFGRSAREAPPR PLGPRARGHSGRGARAALPGGAVARPLPVRLVPA SSRTKHACARRASALAASVASAGRSPPFSGADW PRC*SVAAAAAAAPHWRTEGRKRRG*RLFGRSG LDRTPETKAPKARGTVALRRLCSGLLTPGIYAPS FFSSDSSLLPSPRPLTRGLSPCREGRDGGPAQA FPCAAAIVPLRSRYFSLPQPLPLAAAAAAAASP APPFARSQLRPAGGAPGPAPRHRPAALPIGGRGG YKGRAQAAPGSLPPPF*IQLHTTLRRRCCRDPD CAPAPPCRQLRHYGGYERVQQYRGIRRGIQDQR EQESAG*R*NVYWRLELGYKQKRSDRVLVSIWGS CRLHN*NRSSHWEIKRIWICAFQRCC*C**GFG TERTQTGWQIDRSQKGQSFKRERTSQKGFCGWI EPGYF*RTN*RIFWSLWRD*KY*TSHGYKNK*KK RILFYHIY**RASKKIVRKQIPSNWFWEV*NQS CTTQRGI*AATATTKRWKRCCSWWTRWYEGSWP RSGPKLEPRI**LL*SRIWKLQ*CLWW*SKL*WL WRI*LYWV*LWELWIWTGICRLQWPTEHLWQGI SRGWQSPKQLPAILKENIGENRRRC*SNPSCRT TLKIGLLLI*DDYFVKDFLVYKTPLCPTVYSCQL VFFVFTLSFAICVMTQCGFVYTHFICIISC*TS NKCFLM*LLFCVRYYIAL*KM*FKISNN*GTVD FVEYWSIQRNCGPL*IASQRHPLLQFVGVFYALK ASSSPCN*DFYHTFEQCSFPSGYLKTVLKGRHK CCD**KLCNHNTMSNS**KFRYKRSTVKLVGAM V*EHWK*LQLKDFGRKV*VWSKN*NSGKIRFSCV FSEPPQD*TKCFLFGHPEEVVLAVNAL*V*KKS ***I*FLTQCMN*VVKYLHIQKGIVEKVSWL*Q SHYKCD*VITNVTESLQWTLWVH*KESVLYPGFR GPGIIKSFGFCIQCSWILGPWPQCYLLGLAYVF TGRVVDLTQRVISQNW*VSYAHEPSLFFFNLVP ATFLTMILLPGLSHYNALGLFFAAVLLFLNLGQV PMLAVRRDSVHSTCNFREWK*VHF*VVLSVGAV SRVVNPVSSNL*LGDELTLRLSFSLIKK*IKPF *

Frame 1

SSGQPPPLLPASARQRPRGARASADQPGRPRRA PLARAPVVTVEEAPALRCPEEPSRARFLFGWFL PARGQNTRARGGRARSPPQSPAPGAVRLFPEQTG RGASR*QRPPQRLRTGEPRAEKGGVDGFLVGVG WTGRQRQRLPRQEGLWPCVGSARDC*PQEFTPL RFSLLILLFSQARVPSRVASLLAGRAAMEVPPRL SHVPPPLFPSAPATLASRSLSHWRPRPPRQLAP LLPSLAPSSARQGARRAQRHVTAQQPSRLAGGA AIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRT ARQHPPADSSVTMEDMNEYSNIEEFAEGSKINA SKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGE VVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLE LKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGL SPDTSEEQIKEYFGAFGEIENIELPMDTKTNER RGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKV AQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGR GQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSG YGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKAS RGGGNHQNNYQPY*RRTLEKTGGDVKVTHLAGR H*RLVFC*SKMIIL*KTF*CTRHHCVQLYIAAN *FSLFLLCPLLSVL*LNVDLFIHILFVSFHVKPQ INASLCDCFSASGTT*LCKKCNLK*AIIKAQLI L*SIGPYRETVVLYK*PASVTLFSNL*VYFMLL RLHLLPVTEISTTPLNNVLSLLVI*RLS*KEDIS VVISRSFVIITQ*VILDKSSDTKGAL*NW*ELW FKSIGSSYNSRILVERYEFGRKIKIVAK*DLVV FSQSRHKIEQNVFCLGILRKLY*LLMLCEFRKSL DSKSSF*HSA*TK*LNIYIFRKE*WKRYLGYDK VITNVTKSLQM*LSHYSGPSGCIEKNPFYIQVS EDLE**KALDFAFSVVGFWDLGLSVIYWDWHTCS QAE*LISHNG*SHKTGKFLMLMSPPFFFLIWCL QLS*Q*FYFLGYHIIMLLASFLLLFCYS*T*AK YQCWLLEGILFIQHATLGNGSKFIFKLCCQ*VRC LG**IL*VQIYD*VTS*H*DCPFP*SKNE*SLF K

Frame 2

HLASPRPSSRRQPARGRAGPGLRPISPGGPAAP PWPARPWSQWKRRPRCAARRSRRAPASCSAGSC QLEDKTRVRAAGERARRLSRQRRAQSAFFRSRL AAVLVGSSGRRSGSALANRGQKKAGLTAFW*EWA GPDARDKGSQGKRDCGPASALLGTADPRNLRPF VFLF*FFSSPKPASPHAWPLSLPGGPRWRSRPG FPMCRRHCSPPLPLL*PPAASPIGGRGRRGS*PR SSLRSLPAPPGRGRAGPSATSPPSSPPDWRAGR L*REGAGGARISSAAILNPAPYNAPPPLLPRPG LRASTPLPTAPSLWRI*TSTAI*RNSQRDPRSTR ARISRMTVKCLLEA*AGIQAKKI*QSTCLDLGK L*TAQLKQIQSLGDQEDLDLCFSKMLLVLIRFW N*KNTNWMAN**IPKGPKL*KGKNLPKRFLWVD* ARILLKNKLKNILEPLERLKILNFPWIQKQMKE EDFVLSHILMKSQ*KNC*KADTIKLVLGSVKSK LHNPKRYIGSNSNNKKVEEVLQLVDEVVRGVVAE VRAKTGTKDLITIMIKDMEITIVPMVVIKTIVA MADMIILGITMGTMDMDRDMQTTVANRALMARH LEGVAITKTITSHTKGEHWRKQEEMLK*PILQDD IEDWSSVDLR*LFCKRLSSVQDTIVSNCI*LPI SFLCFYFVLCYLCYDSMWICLYTFYLYHFMLNL K*MLPYVIAFLRQVLHSSVKNVI*NKQ*LRHS*F CRVLVHTEKLWSFINSQPASPSSPICRCILCS* GFIFSL*LRFLPHL*TMFFPFWLSEDCPERKT* VL*LVEAL*S*HNE*FLIKVQIQKEHCKTGRSYG LRALEVVTTQGFW*KGMSLVEKLK*WQNKI*LC FLRAATRLNKMFSVWAS*GSCISC*CSVSLEKV LIVNLVFDTVHELSS*IFTYSERNSGKGILVMTK SLQM*LSHYKCD*VITVDPLGALKRIRFISRFQ RTWNNKKLWILHSV*LDFGTLASVLFTGIGIRV HRQSS*SHTTGDLTKLVSFLCS*ALPFFF*FGAC NFLNNDSTSWAITL*CSWPLFCCCFAILKLRPS TNVGC*KGFCSFNMQL*GMEVSSFLSCVVSRCG V*GSESCKFKFMIR*RVDIEIVLFPDQKMNKAFL N

Sequence NM_005463

GTCATCTGGCCAGCCCCCGCCCCTCCTCCCGGCGTCAGCCCGCCAGAGGCCGCGCGGGGCCCGGGCTTCGGCCGATCAGCCCGGGAGGCCCCGCCGCGCC CCCTTGGCCCGCGCGCCCGTGGTCACAGTGGAAGAGGCGCCCGCGCTGCGCTGCCCGGAGGAGCCGTCGCGCGCCCGCTTCCTGTTCGGCTGGTTCCTGC CAGCTCGAGGACAAAACACGCGTGCGCGCGGCGGGCGAGCGCGCTCGCCGCCTCAGTCGCCAGCGCCGGGCGCAGTCCGCCTTTTTCCGGAGCAGACTGG CCGCGGTGCTAGTCGGTAGCAGCGGCCGCCGCAGCGGCTCCGCACTGGCGAACCGAGGGCAGAAAAAGGCGGGGTTGACGGCTTTTTGGTAGGAGTGGGC TGGACCGGACGCCAGAGACAAAGGCTCCCAAGGCAAGAGGGACTGTGGCCCTGCGTCGGCTCTGCTCGGGACTGCTGACCCCAGGAATTTACGCCCCTTC GTTTTTCTCTTCTGATTCTTCTCTTCTCCCAAGCCCGCGTCCCCTCACGCGTGGCCTCTCTCCTTGCCGGGAGGGCCGCGATGGAGGTCCCGCCCAGGCT TTCCCATGTGCCGCCGCCATTGTTCCCCTCCGCTCCCGCTACTTTAGCCTCCCGCAGCCTCTCCCATTGGCGGCCGCGGCCGCCGCGGCAGCTAGCCCCG CTCCTCCCTTCGCTCGCTCCCAGCTCCGCCCGGCAGGGGGCGCGCCGGGCCCAGCGCCACGTCACCGCCCAGCAGCCCTCCCGATTGGCGGGCGGGGCGG CTATAAAGGGAGGGCGCAGGCGGCGCCCGGATCTCTTCCGCCGCCATTTTAAATCCAGCTCCATACAACGCTCCGCCGCCGCTGCTGCCGCGACCCGGAC TGCGCGCCAGCACCCCCCTGCCGACAGCTCCGTCACTATGGAGGATATGAACGAGTACAGCAATATAGAGGAATTCGCAGAGGGATCCAAGATCAACGCG AGCAAGAATCAGCAGGATGACGGTAAAATGTTTATTGGAGGCTTGAGCTGGGATACAAGCAAAAAAGATCTGACAGAGTACTTGTCTCGATTTGGGGAAG TTGTAGACTGCACAATTAAAACAGATCCAGTCACTGGGAGATCAAGAGGATTTGGATTTGTGCTTTTCAAAGATGCTGCTAGTGTTGATAAGGTTTTGGA ACTGAAAGAACACAAACTGGATGGCAAATTGATAGATCCCAAAAGGGCCAAAGCTTTAAAAGGGAAAGAACCTCCCAAAAAGGTTTTTGTGGGTGGATTG AGCCCGGATACTTCTGAAGAACAAATTAAAGAATATTTTGGAGCCTTTGGAGAGATTGAAAATATTGAACTTCCCATGGATACAAAAACAAATGAAAGAA GAGGATTTTGTTTTATCACATATACTGATGAAGAGCCAGTAAAAAAATTGTTAGAAAGCAGATACCATCAAATTGGTTCTGGGAAGTGTGAAATCAAAGT TGCACAACCCAAAGAGGTATATAGGCAGCAACAGCAACAACAAAAAGGTGGAAGAGGTGCTGCAGCTGGTGGACGAGGTGGTACGAGGGGTCGTGGCCGA GGTCAGGGCCAAAACTGGAACCAAGGATTTAATAACTATTATGATCAAGGATATGGAAATTACAATAGTGCCTATGGTGGTGATCAAAACTATAGTGGCT ATGGCGGATATGATTATACTGGGTATAACTATGGGAACTATGGATATGGACAGGGATATGCAGACTACAGTGGCCAACAGAGCACTTATGGCAAGGCATC TCGAGGGGGTGGCAATCACCAAAACAATTACCAGCCATACTAAAGGAGAACATTGGAGAAAACAGCGGGAACTTCATTGCAGGCCGTGTGTCACCCTGAC CACGTCTATCTCTGGGGGTCGCACGTTGCGGGCAGAGCGCAAGGCATACACCAGAAAACGCTGTCCTGTGGAGGAGATGTTAAAGTAACCCATCTTGCAG GACGACATTGAAGATTGGTCTTCTGTTGATCTAAGATGATTATTTTGTAAAAGACTTTCTAGTGTACAAGACACCATTGTGTCCAACTGTATATAGCTGC CAATTAGTTTTCTTTGTTTTTACTTTGTCCTTTGCTATCTGTGTTATGACTCAATGTGGATTTGTTTATACACATTTTATTTGTATCATTTCATGTTAAA CCTCAAATAAATGCTTCCTTATGTGATTGCTTTTCTGCGTCAGGTACTACATAGCTCTGTAAAAAATGTAATTTAAAATAAGCAATAATTAAGGCACAGT TGATTTTGTAGAGTATTGGTCCATACAGAGAAACTGTGGTCCTTTATAAATAGCCAGCCAGCGTCACCCTCTTCTCCAATTTGTAGGTGTATTTTATGCT CTTAAGGCTTCATCTTCTCCCTGTAACTGAGATTTCTACCACACCTTTGAACAATGTTCTTTCCCTTCTGGTTATCTGAAGACTGTCCTGAAAGGAAGAC ATAAGTGTTGTGATTAGTAGAAGCTTTGTAATCATAACACAATGAGTAATTCTTGATAAAAGTTCAGATACAAAAGGAGCACTGTAAAACTGGTAGGAGC TATGGTTTAAGAGCATTGGAAGTAGTTACAACTCAAGGATTTTGGTAGAAAGGTATGAGTTTGGTCGAAAAATTAAAATAGTGGCAAAATAAGATTTAGT TGTGTTTTCTCAGAGCCGCCACAAGATTGAACAAAATGTTTTCTGTTTGGGCATCCTGAGGAAGTTGTATTAGCTGTTAATGCTCTGTGAGTTTAGAAAA AGTCTTGATAGTAAATCTAGTTTTTGACACAGTGCATGAACTAAGTAGTTAAATATTTACATATTCAGAAAGGAATAGTGGAAAAGGTATCTTGGTTATG ACAAAGTCATTACAAATGTGACTAAGTCATTACAAATGTGACTGAGTCATTACAGTGGACCCTCTGGGTGCATTGAAAAGAATCCGTTTTATATCCAGGT TTCAGAGGACCTGGAATAATAAAAAGCTTTGGATTTTGCATTCAGTGTAGTTGGATTTTGGGACCTTGGCCTCAGTGTTATTTACTGGGATTGGCATACG TGTTCACAGGCAGAGTAGTTGATCTCACACAACGGGTGATCTCACAAAACTGGTAAGTTTCTTATGCTCATGAGCCCTCCCTTTTTTTTTTTAATTTGGT GCCTGCAACTTTCTTAACAATGATTCTACTTCCTGGGCTATCACATTATAATGCTCTTGGCCTCTTTTTTGCTGCTGTTTTGCTATTCTTAAACTTAGGC CAAGTACCAATGTTGGCTGTTAGAAGGGATTCTGTTCATTCAACATGCAACTTTAGGGAATGGAAGTAAGTTCATTTTTAAGTTGTGTTGTCAGTAGGTG CGGTGTCTAGGGTAGTGAATCCTGTAAGTTCAAATTTATGATTAGGTGACGAGTTGACATTGAGATTGTCCTTTTCCCTGATCAAAAAATGAATAAAGCC TTTTTAAAC

refseq_HNRPDL.F1 (forward primer)
refseq_HNRPDL.R1 (reverse primer)
Single exon skipping

Frame 0

VIWPAPAPPPGVSPPEAARGPGFGRSAREAPPR PLGPRARGHSGRGARAALPGGAVARPLPVRLVPA SSRTKHACARRASALAASVASAGRSPPFSGADW PRC*SVAAAAAAAPHWRTEGRKRRG*RLFGRSG LDRTPETKAPKARGTVALRRLCSGLLTPGIYAPS FFSSDSSLLPSPRPLTRGLSPCREGRDGGPAQA FPCAAAIVPLRSRYFSLPQPLPLAAAAAAAASP APPFARSQLRPAGGAPGPAPRHRPAALPIGGRGG YKGRAQAAPGSLPPPF*IQLHTTLRRRCCRDPD CAPAPPCRQLRHYGGYERVQQYRGIRRGIQDQR EQESAG*R*NVYWRLELGYKQKRSDRVLVSIWGS CRLHN*NRSSHWEIKRIWICAFQRCC*C**GFG TERTQTGWQIDRSQKGQSFKRERTSQKGFCGWI EPGYF*RTN*RIFWSLWRD*KY*TSHGYKNK*KK RILFYHIY**RASKKIVRKQIPSNWFWEV*NQS CTTQRGI*AATATTKRWKRCCSWWTRWYEGSWP RSGPKLEPRI**LL*SRIWKLQ*CLWW*SKL*WL WRI*LYWV*LWELWIWTGICRLQWPTEHLWQGI SRGWQSPKQLPAILKENIGENSGNFIAGRVSP* PRLSLGVARCGQSARHTPENAVLWRRC*SNPSCR TTLKIGLLLI*DDYFVKDFLVYKTPLCPTVYSC QLVFFVFTLSFAICVMTQCGFVYTHFICIISC* TSNKCFLM*LLFCVRYYIAL*KM*FKISNN*GTV DFVEYWSIQRNCGPL*IASQRHPLLQFVGVFYA LKASSSPCN*DFYHTFEQCSFPSGYLKTVLKGR HKCCD**KLCNHNTMSNS**KFRYKRSTVKLVGA MV*EHWK*LQLKDFGRKV*VWSKN*NSGKIRFS CVFSEPPQD*TKCFLFGHPEEVVLAVNAL*V*K KS***I*FLTQCMN*VVKYLHIQKGIVEKVSWL* QSHYKCD*VITNVTESLQWTLWVH*KESVLYPG FRGPGIIKSFGFCIQCSWILGPWPQCYLLGLAY VFTGRVVDLTQRVISQNW*VSYAHEPSLFFFNLV PATFLTMILLPGLSHYNALGLFFAAVLLFLNLG QVPMLAVRRDSVHSTCNFREWK*VHF*VVLSVG AVSRVVNPVSSNL*LGDELTLRLSFSLIKK*IKP F*

Frame 1

SSGQPPPLLPASARQRPRGARASADQPGRPRRA PLARAPVVTVEEAPALRCPEEPSRARFLFGWFL PARGQNTRARGGRARSPPQSPAPGAVRLFPEQTG RGASR*QRPPQRLRTGEPRAEKGGVDGFLVGVG WTGRQRQRLPRQEGLWPCVGSARDC*PQEFTPL RFSLLILLFSQARVPSRVASLLAGRAAMEVPPRL SHVPPPLFPSAPATLASRSLSHWRPRPPRQLAP LLPSLAPSSARQGARRAQRHVTAQQPSRLAGGA AIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRT ARQHPPADSSVTMEDMNEYSNIEEFAEGSKINA SKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGE VVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLE LKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGL SPDTSEEQIKEYFGAFGEIENIELPMDTKTNER RGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKV AQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGR GQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSG YGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKAS RGGGNHQNNYQPY*RRTLEKTAGTSLQAVCHPD HVYLWGSHVAGRAQGIHQKTLSCGGDVKVTHLA GRH*RLVFC*SKMIIL*KTF*CTRHHCVQLYIAA N*FSLFLLCPLLSVL*LNVDLFIHILFVSFHVK PQINASLCDCFSASGTT*LCKKCNLK*AIIKAQ LIL*SIGPYRETVVLYK*PASVTLFSNL*VYFML LRLHLLPVTEISTTPLNNVLSLLVI*RLS*KED ISVVISRSFVIITQ*VILDKSSDTKGAL*NW*E LWFKSIGSSYNSRILVERYEFGRKIKIVAK*DLV VFSQSRHKIEQNVFCLGILRKLY*LLMLCEFRK SLDSKSSF*HSA*TK*LNIYIFRKE*WKRYLGY DKVITNVTKSLQM*LSHYSGPSGCIEKNPFYIQV SEDLE**KALDFAFSVVGFWDLGLSVIYWDWHT CSQAE*LISHNG*SHKTGKFLMLMSPPFFFLIW CLQLS*Q*FYFLGYHIIMLLASFLLLFCYS*T*A KYQCWLLEGILFIQHATLGNGSKFIFKLCCQ*V RCLG**IL*VQIYD*VTS*H*DCPFP*SKNE*S LFK

Frame 2

HLASPRPSSRRQPARGRAGPGLRPISPGGPAAP PWPARPWSQWKRRPRCAARRSRRAPASCSAGSC QLEDKTRVRAAGERARRLSRQRRAQSAFFRSRL AAVLVGSSGRRSGSALANRGQKKAGLTAFW*EWA GPDARDKGSQGKRDCGPASALLGTADPRNLRPF VFLF*FFSSPKPASPHAWPLSLPGGPRWRSRPG FPMCRRHCSPPLPLL*PPAASPIGGRGRRGS*PR SSLRSLPAPPGRGRAGPSATSPPSSPPDWRAGR L*REGAGGARISSAAILNPAPYNAPPPLLPRPG LRASTPLPTAPSLWRI*TSTAI*RNSQRDPRSTR ARISRMTVKCLLEA*AGIQAKKI*QSTCLDLGK L*TAQLKQIQSLGDQEDLDLCFSKMLLVLIRFW N*KNTNWMAN**IPKGPKL*KGKNLPKRFLWVD* ARILLKNKLKNILEPLERLKILNFPWIQKQMKE EDFVLSHILMKSQ*KNC*KADTIKLVLGSVKSK LHNPKRYIGSNSNNKKVEEVLQLVDEVVRGVVAE VRAKTGTKDLITIMIKDMEITIVPMVVIKTIVA MADMIILGITMGTMDMDRDMQTTVANRALMARH LEGVAITKTITSHTKGEHWRKQRELHCRPCVTLT TSISGGRTLRAERKAYTRKRCPVEEMLK*PILQ DDIEDWSSVDLR*LFCKRLSSVQDTIVSNCI*L PISFLCFYFVLCYLCYDSMWICLYTFYLYHFMLN LK*MLPYVIAFLRQVLHSSVKNVI*NKQ*LRHS *FCRVLVHTEKLWSFINSQPASPSSPICRCILC S*GFIFSL*LRFLPHL*TMFFPFWLSEDCPERKT *VL*LVEAL*S*HNE*FLIKVQIQKEHCKTGRS YGLRALEVVTTQGFW*KGMSLVEKLK*WQNKI* LCFLRAATRLNKMFSVWAS*GSCISC*CSVSLEK VLIVNLVFDTVHELSS*IFTYSERNSGKGILVM TKSLQM*LSHYKCD*VITVDPLGALKRIRFISR FQRTWNNKKLWILHSV*LDFGTLASVLFTGIGIR VHRQSS*SHTTGDLTKLVSFLCS*ALPFFF*FG ACNFLNNDSTSWAITL*CSWPLFCCCFAILKLR PSTNVGC*KGFCSFNMQL*GMEVSSFLSCVVSRC GV*GSESCKFKFMIR*RVDIEIVLFPDQKMNKA FLN