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Sequences

Sequence NM_000167

GCGTTCAGCGGACGCGCGCGGCCTCGATCTCTGGACTCGTCACCTGCCCCTCCCCCTCCCGCCGCCGTCACCCAGGAAACCGGCCGCAATCGCCGGCCGA
CCTGAAGCTGGTTTCATGGCAGCCTCAAAGAAGGCAGTTTTGGGGCCATTGGTGGGGGCGGTGGACCAGGGCACCAGTTCGACGCGCTTTTTGGTTTTCA
ATTCAAAAACAGCTGAACTACTTAGTCATCATCAAGTAGAAATAAAACAAGAGTTCCCAAGAGAAGGATGGGTGGAACAGGACCCTAAGGAAATTCTACA
TTCTGTCTATGAGTGTATAGAGAAAACATGTGAGAAACTTGGACAGCTCAATATTGATATTTCCAACATAAAAGCTATTGGTGTCAGCAACCAGAGGGAA
ACCACTGTAGTCTGGGACAAGATAACTGGAGAGCCTCTCTACAATGCTGTGGTGTGGCTTGATCTAAGAACCCAGTCTACCGTTGAGAGTCTTAGTAAAA
GAATTCCAGGAAATAATAACTTTGTCAAGTCCAAGACAGGCCTTCCACTTAGCACTTACTTCAGTGCAGTGAAACTTCGTTGGCTCCTTGACAATGTGAG
AAAAGTTCAAAAGGCCGTTGAAGAAAAACGAGCTCTTTTTGGGACTATTGATTCATGGCTTATTTGGAGTTTGACAGGAGGAGTCAATGGAGGTGTCCAC
TGTACAGATGTAACAAATGCAAGTAGGACTATGCTTTTCAACATTCATTCTTTGGAATGGGATAAACAACTCTGCGAATTTTTTGGAATTCCAATGGAAA
TTCTTCCAAATGTCCGGAGTTCTTCTGAGATCTATGGCCTAATGAAAGCTGGGGCCTTGGAAGGTGTGCCAATATCTGGGTGTTTAGGGGACCAGTCTGC
TGCATTGGTGGGACAAATGTGCTTCCAGATTGGACAAGCCAAAAATACGTATGGAACAGGATGTTTCTTACTATGTAATACAGGCCATAAGTGTGTATTT
TCTGATCATGGCCTTCTCACCACAGTGGCTTACAAACTTGGCAGAGACAAACCAGTATATTATGCTTTGGAAGGTTCTGTAGCTATAGCTGGTGCTGTTA
TTCGCTGGCTAAGAGACAATCTTGGAATTATAAAGACCTCAGAAGAAATTGAAAAACTTGCTAAAGAAGTAGGTACTTCTTATGGCTGCTACTTCGTCCC
AGCATTTTCGGGGTTATATGCACCTTATTGGGAGCCCAGCGCAAGAGGGATAATCTGTGGACTCACTCAGTTCACCAATAAATGCCATATTGCTTTTGCT
GCATTAGAAGCTGTTTGTTTCCAAACTCGAGAGATTTTGGATGCCATGAATCGAGACTGTGGAATTCCACTCAGTCATTTGCAGGTAGATGGAGGAATGA
CCAGCAACAAAATTCTTATGCAGCTACAAGCAGACATTCTGTATATACCAGTAGTGAAGCCCTCAATGCCCGAAACCACTGCACTGGGTGCGGCTATGGC
GGCAGGGGCTGCAGAAGGAGTCGGCGTATGGAGTCTCGAACCCGAGGATTTGTCTGCCGTCACGATGGAGCGGTTTGAACCTCAGATTAATGCGGAGGAA
AGTGAAATTCGTTATTCTACATGGAAGAAAGCTGTGATGAAGTCAATGGGTTGGGTTACAACTCAATCTCCAGAAAGTGGTATTCCATAAAACCTACCAA
CTCATGGATTCCCAAGATGTGAGCTTTTTACATAATGAAAGAACCCAGCAATTCTGTCTCTTAATGCAATGACACTATTCATAGACTTTGATTTTATTTA
TAAGCCACTTGCTGCATGACCCTCCAAGTAGACCTGTGGCTTAAAATAAAGAAAATGCAGCAAAAAGAATGCTATAGAAATATTTGGTGGTTTTTTTTTT
TTTTAAACATCCACAGTTAAGGTTGGGCCAGCTACCTTTGGGGCTGACCCCCTCCATTGCCATAACATCCTGCTCCATTCCCTCTAAGATGTAGGAAGAA
TTCGGATCCTTACCATTGGAATCTTCCATCGAACATACTCAAACACTTTTGGACCAGGATTTGAGTCTCTGCATGACATATACTTGATTAAAAGGTTATT
ACTAACCTGTTAAAAATCAGCAGCTCTTTGCTTTTAACAGACACCCTAAAAGTCTTCTTTTCTACATAGTTGAAGACAGCAACATCTTCACTGAATGTTT
GAATAGAAACCTCTACTAAATTATTAAAATAGACATTTAGTGTTCTCACAGCTTGGATATTTTTCTGAAAAGTTATTTGCCAAAACTGAAATCCTTCAGA
TGTTTTCCATGGTCCCACTAATTATAATGACTTTCTGTCTGGATCTTATAGGAAAAGATACTTTCTTTTTTCTTCCATCTTTCCTTTTTATATTTTTTAC
TTTGTATGTATAACATACATGCCTATATATTTTATACACTGAGGGTAGCCCATTTATAAATTAAGAGCACATTATATTCAGAAGGTTCTAACAGGGCTGG
TCTTAAGTGAACCACTGTGTATATAAATATGTTGGAAAACAGCTGTATACATTTTTGGGCAACGGTTATGCATAATATTTACCAGGAGAATTTTTTTCTT
AACAAGCCAACATTTAAAATTTATGTTTTATGTCAATAAAAGAAAATATACTTTATTGTGACTTCAACTATATTTCTTATCCCTTACATTTTTATTTAAT
TGTCTTAGCTTAAAAAAAGAAGAAACTGTGGAATACTACAGTAAATATTGTTTTCAAACACAAGCAATAATTCAAATAGTTATTTTTCTTTTGAATTAAT
TTTAGACATATTTTGGATCCTATTGAGGGGATAAGAGGATGTCAAAAAAGTTAAATACCTAAGTAGAAAAAAATATAGAAATAAAGCCAAGAATCTCTTT
CAGTTCAAATGTTATCAATTGTTAATAAGAAATTGCTATCTGGGATGACAGAATTACCTCTGCTTAGTATCTCATTATAACTGAAAGAAGGTTTATCATT
ACAAATACCTTCCAATGAAACCAAGAATTTCTCAAAATATTTAATGTCACATATTATAAGAAGTTACCTAATCCTGCTTCTTAACATCAATTTTTAAAAA
TATCTTAAAATTACTTTGTTTTGTAGTAAACAGTGAAGAAAAGATTGCCTCCTAATTATTTTTTTCAATGAGTGCTGAATGGGAAAACATTTATATCTTA
CTATAAAAGGTTCTGTTTTGTTTGGAATCAATGGTAGCTTTATTGACTGTTCTGATTGTGCTGTTTCTAATTTATTGAATCTGCTAGGTTTTATTGATGC
AGCCACCACTTAAGTGACATAAATATTATAGAAAGGTACTGTGAAATGATCACTTTGTGGCAGGGGTACTTTTAAACATAAATGTTTCTACAAAAGTAGG
TTGAGTTCATTGTAAATAATTGTGAAAGCCACTGTTCAAATAATTTTAAGATTACATTAATTTTTCTATAAATTGGAAGATTTATAAATGTTTGAAATTG
TACACATTGATATTTAATGACAAATTTACTTAAAATAAATTGACCCCTTGTTCTTA
  • refseq_GK.F1 (forward primer)
  • refseq_GK.R1 (reverse primer)
  • Single exon skipping

Frame 0

AFSGRARPRSLDSSPAPPPPAAVTQETGRNRRP
T*SWFHGSLKEGSFGAIGGGGGPGHQFDALFGFQ
FKNS*TT*SSSSRNKTRVPKRRMGGTGP*GNST
FCL*VYRENM*ETWTAQY*YFQHKSYWCQQPEG
NHCSLGQDNWRASLQCCGVA*SKNPVYR*ES**K
NSRK**LCQVQDRPST*HLLQCSETSLAP*QCE
KSSKGR*RKTSSFWDY*FMAYLEFDRRSQWRCP
LYRCNKCK*DYAFQHSFFGMG*TTLRIFWNSNGN
SSKCPEFF*DLWPNESWGLGRCANIWVFRGPVC
CIGGTNVLPDWTSQKYVWNRMFLTM*YRP*VCI
F*SWPSHHSGLQTWQRQTSILCFGRFCSYSWCCY
SLAKRQSWNYKDLRRN*KTC*RSRYFLWLLLRP
SIFGVICTLLGAQRKRDNLWTHSVHQ*MPYCFC
CIRSCLFPNSRDFGCHESRLWNSTQSFAGRWRND
QQQNSYAATSRHSVYTSSEALNARNHCTGCGYG
GRGCRRSRRMESRTRGFVCRHDGAV*TSD*CGG
K*NSLFYMEESCDEVNGLGYNSISRKWYSIKPTN
SWIPKM*AFYIMKEPSNSVS*CNDTIHRL*FYL
*ATCCMTLQVDLWLKIKKMQQKECYRNIWWFFF
FLNIHS*GWASYLWG*PPPLP*HPAPFPLRCRKN
SDPYHWNLPSNILKHFWTRI*VSA*HILD*KVI
TNLLKISSSLLLTDTLKVFFST*LKTATSSLNV
*IETSTKLLK*TFSVLTAWIFF*KVICQN*NPSD
VFHGPTNYNDFLSGSYRKRYFLFSSIFPFYIFY
FVCITYMPIYFIH*G*PIYKLRAHYIQKVLTGL
VLSEPLCI*ICWKTAVYIFGQRLCIIFTRRIFFL
TSQHLKFMFYVNKRKYTLL*LQLYFLSLTFLFN
CLSLKKEETVEYYSKYCFQTQAIIQIVIFLLN*
F*TYFGSY*GDKRMSKKLNT*VEKNIEIKPRISF
SSNVINC**EIAIWDDRITSA*YLIITERRFII
TNTFQ*NQEFLKIFNVTYYKKLPNPAS*HQFLK
IS*NYFVL**TVKKRLPPNYFFQ*VLNGKTFISY
YKRFCFVWNQW*LY*LF*LCCF*FIESARFY*C
SHHLSDINIIERYCEMITLWQGYF*T*MFLQK*
VEFIVNNCESHCSNNFKITLIFL*IGRFINV*NC
TH*YLMTNLLKIN*PLVL

Frame 1

RSADARGLDLWTRHLPLPLPPPSPRKPAAIAGR
PEAGFMAASKKAVLGPLVGAVDQGTSSTRFLVF
NSKTAELLSHHQVEIKQEFPREGWVEQDPKEILH
SVYECIEKTCEKLGQLNIDISNIKAIGVSNQRE
TTVVWDKITGEPLYNAVVWLDLRTQSTVESLSK
RIPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVR
KVQKAVEEKRALFGTIDSWLIWSLTGGVNGGVH
CTDVTNASRTMLFNIHSLEWDKQLCEFFGIPME
ILPNVRSSSEIYGLMKAGALEGVPISGCLGDQSA
ALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVF
SDHGLLTTVAYKLGRDKPVYYALEGSVAIAGAV
IRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVP
AFSGLYAPYWEPSARGIICGLTQFTNKCHIAFA
ALEAVCFQTREILDAMNRDCGIPLSHLQVDGGM
TSNKILMQLQADILYIPVVKPSMPETTALGAAMA
AGAAEGVGVWSLEPEDLSAVTMERFEPQINAEE
SEIRYSTWKKAVMKSMGWVTTQSPESGIP*NLP
THGFPRCELFT**KNPAILSLNAMTLFIDFDFIY
KPLAA*PSK*TCGLK*RKCSKKNAIEIFGGFFF
F*TSTVKVGPATFGADPLHCHNILLHSL*DVGR
IRILTIGIFHRTYSNTFGPGFESLHDIYLIKRLL
LTC*KSAALCF*QTP*KSSFLHS*RQQHLH*MF
E*KPLLNY*NRHLVFSQLGYFSEKLFAKTEILQ
MFSMVPLIIMTFCLDLIGKDTFFFLPSFLFIFFT
LYV*HTCLYILYTEGSPFIN*EHIIFRRF*QGW
S*VNHCVYKYVGKQLYTFLGNGYA*YLPGEFFS
*QANI*NLCFMSIKENILYCDFNYISYPLHFYLI
VLA*KKKKLWNTTVNIVFKHKQ*FK*LFFF*IN
FRHILDPIEGIRGCQKS*IPK*KKI*K*SQESL
SVQMLSIVNKKLLSGMTELPLLSISL*LKEGLSL
QIPSNETKNFSKYLMSHIIRSYLILLLNINF*K
YLKITLFCSKQ*RKDCLLIIFFNEC*MGKHLYL
TIKGSVLFGINGSFIDCSDCAVSNLLNLLGFIDA
ATT*VT*IL*KGTVK*SLCGRGTFKHKCFYKSR
LSSL*IIVKATVQIILRLH*FFYKLEDL*MFEI
VHIDI**QIYLK*IDPLFL

Frame 2

VQRTRAASISGLVTCPSPSRRRHPGNRPQSPAD
LKLVSWQPQRRQFWGHWWGRWTRAPVRRAFWFS
IQKQLNYLVIIK*K*NKSSQEKDGWNRTLRKFY
ILSMSV*RKHVRNLDSSILIFPT*KLLVSATRGK
PL*SGTR*LESLSTMLWCGLI*EPSLPLRVLVK
EFQEIITLSSPRQAFHLALTSVQ*NFVGSLTM*
EKFKRPLKKNELFLGLLIHGLFGV*QEESMEVST
VQM*QMQVGLCFSTFILWNGINNSANFLEFQWK
FFQMSGVLLRSMA**KLGPWKVCQYLGV*GTSL
LHWWDKCASRLDKPKIRMEQDVSYYVIQAISVYF
LIMAFSPQWLTNLAETNQYIMLWKVL*L*LVLL
FAG*ETILEL*RPQKKLKNLLKK*VLLMAATSS
QHFRGYMHLIGSPAQEG*SVDSLSSPINAILLLL
H*KLFVSKLERFWMP*IETVEFHSVICR*MEE*
PATKFLCSYKQTFCIYQ**SPQCPKPLHWVRLW
RQGLQKESAYGVSNPRICLPSRWSGLNLRLMRRK
VKFVILHGRKL**SQWVGLQLNLQKVVFHKTYQ
LMDSQDVSFLHNERTQQFCLLMQ*HYS*TLILF
ISHLLHDPPSRPVA*NKENAAKRML*KYLVVFFF
FKHPQLRLGQLPLGLTPSIAITSCSIPSKM*EE
FGSLPLESSIEHTQTLLDQDLSLCMTYT*LKGY
Y*PVKNQQLFAFNRHPKSLLFYIVEDSNIFTECL
NRNLY*IIKIDI*CSHSLDIFLKSYLPKLKSFR
CFPWSH*L**LSVWIL*EKILSFFFHLSFLYFL
LCMYNIHAYIFYTLRVAHL*IKSTLYSEGSNRAG
LK*TTVYINMLENSCIHFWATVMHNIYQENFFL
NKPTFKIYVLCQ*KKIYFIVTSTIFLIPYIFI*
LS*LKKRRNCGILQ*ILFSNTSNNSNSYFSFELI
LDIFWILLRG*EDVKKVKYLSRKKYRNKAKNLF
QFKCYQLLIRNCYLG*QNYLCLVSHYN*KKVYH
YKYLPMKPRISQNI*CHIL*EVT*SCFLTSIFKN
ILKLLCFVVNSEEKIAS*LFFSMSAEWENIYIL
L*KVLFCLESMVALLTVLIVLFLIY*IC*VLLM
QPPLK*HKYYRKVL*NDHFVAGVLLNINVSTKVG
*VHCK*L*KPLFK*F*DYINFSINWKIYKCLKL
YTLIFNDKFT*NKLTPCS

Sequence NM_203391

GCGTTCAGCGGACGCGCGCGGCCTCGATCTCTGGACTCGTCACCTGCCCCTCCCCCTCCCGCCGCCGTCACCCAGGAAACCGGCCGCAATCGCCGGCCGA
CCTGAAGCTGGTTTCATGGCAGCCTCAAAGAAGGCAGTTTTGGGGCCATTGGTGGGGGCGGTGGACCAGGGCACCAGTTCGACGCGCTTTTTGGTTTTCA
ATTCAAAAACAGCTGAACTACTTAGTCATCATCAAGTAGAAATAAAACAAGAGTTCCCAAGAGAAGGATGGGTGGAACAGGACCCTAAGGAAATTCTACA
TTCTGTCTATGAGTGTATAGAGAAAACATGTGAGAAACTTGGACAGCTCAATATTGATATTTCCAACATAAAAGCTATTGGTGTCAGCAACCAGAGGGAA
ACCACTGTAGTCTGGGACAAGATAACTGGAGAGCCTCTCTACAATGCTGTGGTGTGGCTTGATCTAAGAACCCAGTCTACCGTTGAGAGTCTTAGTAAAA
GAATTCCAGGAAATAATAACTTTGTCAAGTCCAAGACAGGCCTTCCACTTAGCACTTACTTCAGTGCAGTGAAACTTCGTTGGCTCCTTGACAATGTGAG
AAAAGTTCAAAAGGCCGTTGAAGAAAAACGAGCTCTTTTTGGGACTATTGATTCATGGCTTATTTGGAGTTTGACAGGAGGAGTCAATGGAGGTGTCCAC
TGTACAGATGTAACAAATGCAAGTAGGACTATGCTTTTCAACATTCATTCTTTGGAATGGGATAAACAACTCTGCGAATTTTTTGGAATTCCAATGGAAA
TTCTTCCAAATGTCCGGAGTTCTTCTGAGATCTATGGCCTAATGAAAATCTCTCATAGCGTGAAAGCTGGGGCCTTGGAAGGTGTGCCAATATCTGGGTG
TTTAGGGGACCAGTCTGCTGCATTGGTGGGACAAATGTGCTTCCAGATTGGACAAGCCAAAAATACGTATGGAACAGGATGTTTCTTACTATGTAATACA
GGCCATAAGTGTGTATTTTCTGATCATGGCCTTCTCACCACAGTGGCTTACAAACTTGGCAGAGACAAACCAGTATATTATGCTTTGGAAGGTTCTGTAG
CTATAGCTGGTGCTGTTATTCGCTGGCTAAGAGACAATCTTGGAATTATAAAGACCTCAGAAGAAATTGAAAAACTTGCTAAAGAAGTAGGTACTTCTTA
TGGCTGCTACTTCGTCCCAGCATTTTCGGGGTTATATGCACCTTATTGGGAGCCCAGCGCAAGAGGGATAATCTGTGGACTCACTCAGTTCACCAATAAA
TGCCATATTGCTTTTGCTGCATTAGAAGCTGTTTGTTTCCAAACTCGAGAGATTTTGGATGCCATGAATCGAGACTGTGGAATTCCACTCAGTCATTTGC
AGGTAGATGGAGGAATGACCAGCAACAAAATTCTTATGCAGCTACAAGCAGACATTCTGTATATACCAGTAGTGAAGCCCTCAATGCCCGAAACCACTGC
ACTGGGTGCGGCTATGGCGGCAGGGGCTGCAGAAGGAGTCGGCGTATGGAGTCTCGAACCCGAGGATTTGTCTGCCGTCACGATGGAGCGGTTTGAACCT
CAGATTAATGCGGAGGAAAGTGAAATTCGTTATTCTACATGGAAGAAAGCTGTGATGAAGTCAATGGGTTGGGTTACAACTCAATCTCCAGAAAGTGGTA
TTCCATAAAACCTACCAACTCATGGATTCCCAAGATGTGAGCTTTTTACATAATGAAAGAACCCAGCAATTCTGTCTCTTAATGCAATGACACTATTCAT
AGACTTTGATTTTATTTATAAGCCACTTGCTGCATGACCCTCCAAGTAGACCTGTGGCTTAAAATAAAGAAAATGCAGCAAAAAGAATGCTATAGAAATA
TTTGGTGGTTTTTTTTTTTTTTAAACATCCACAGTTAAGGTTGGGCCAGCTACCTTTGGGGCTGACCCCCTCCATTGCCATAACATCCTGCTCCATTCCC
TCTAAGATGTAGGAAGAATTCGGATCCTTACCATTGGAATCTTCCATCGAACATACTCAAACACTTTTGGACCAGGATTTGAGTCTCTGCATGACATATA
CTTGATTAAAAGGTTATTACTAACCTGTTAAAAATCAGCAGCTCTTTGCTTTTAACAGACACCCTAAAAGTCTTCTTTTCTACATAGTTGAAGACAGCAA
CATCTTCACTGAATGTTTGAATAGAAACCTCTACTAAATTATTAAAATAGACATTTAGTGTTCTCACAGCTTGGATATTTTTCTGAAAAGTTATTTGCCA
AAACTGAAATCCTTCAGATGTTTTCCATGGTCCCACTAATTATAATGACTTTCTGTCTGGATCTTATAGGAAAAGATACTTTCTTTTTTCTTCCATCTTT
CCTTTTTATATTTTTTACTTTGTATGTATAACATACATGCCTATATATTTTATACACTGAGGGTAGCCCATTTATAAATTAAGAGCACATTATATTCAGA
AGGTTCTAACAGGGCTGGTCTTAAGTGAACCACTGTGTATATAAATATGTTGGAAAACAGCTGTATACATTTTTGGGCAACGGTTATGCATAATATTTAC
CAGGAGAATTTTTTTCTTAACAAGCCAACATTTAAAATTTATGTTTTATGTCAATAAAAGAAAATATACTTTATTGTGACTTCAACTATATTTCTTATCC
CTTACATTTTTATTTAATTGTCTTAGCTTAAAAAAAGAAGAAACTGTGGAATACTACAGTAAATATTGTTTTCAAACACAAGCAATAATTCAAATAGTTA
TTTTTCTTTTGAATTAATTTTAGACATATTTTGGATCCTATTGAGGGGATAAGAGGATGTCAAAAAAGTTAAATACCTAAGTAGAAAAAAATATAGAAAT
AAAGCCAAGAATCTCTTTCAGTTCAAATGTTATCAATTGTTAATAAGAAATTGCTATCTGGGATGACAGAATTACCTCTGCTTAGTATCTCATTATAACT
GAAAGAAGGTTTATCATTACAAATACCTTCCAATGAAACCAAGAATTTCTCAAAATATTTAATGTCACATATTATAAGAAGTTACCTAATCCTGCTTCTT
AACATCAATTTTTAAAAATATCTTAAAATTACTTTGTTTTGTAGTAAACAGTGAAGAAAAGATTGCCTCCTAATTATTTTTTTCAATGAGTGCTGAATGG
GAAAACATTTATATCTTACTATAAAAGGTTCTGTTTTGTTTGGAATCAATGGTAGCTTTATTGACTGTTCTGATTGTGCTGTTTCTAATTTATTGAATCT
GCTAGGTTTTATTGATGCAGCCACCACTTAAGTGACATAAATATTATAGAAAGGTACTGTGAAATGATCACTTTGTGGCAGGGGTACTTTTAAACATAAA
TGTTTCTACAAAAGTAGGTTGAGTTCATTGTAAATAATTGTGAAAGCCACTGTTCAAATAATTTTAAGATTACATTAATTTTTCTATAAATTGGAAGATT
TATAAATGTTTGAAATTGTACACATTGATATTTAATGACAAATTTACTTAAAATAAATTGACCCCTTGTTCTTA
  • refseq_GK.F1 (forward primer)
  • refseq_GK.R1 (reverse primer)
  • Single exon skipping

Frame 0

AFSGRARPRSLDSSPAPPPPAAVTQETGRNRRP
T*SWFHGSLKEGSFGAIGGGGGPGHQFDALFGFQ
FKNS*TT*SSSSRNKTRVPKRRMGGTGP*GNST
FCL*VYRENM*ETWTAQY*YFQHKSYWCQQPEG
NHCSLGQDNWRASLQCCGVA*SKNPVYR*ES**K
NSRK**LCQVQDRPST*HLLQCSETSLAP*QCE
KSSKGR*RKTSSFWDY*FMAYLEFDRRSQWRCP
LYRCNKCK*DYAFQHSFFGMG*TTLRIFWNSNGN
SSKCPEFF*DLWPNENLS*RESWGLGRCANIWV
FRGPVCCIGGTNVLPDWTSQKYVWNRMFLTM*Y
RP*VCIF*SWPSHHSGLQTWQRQTSILCFGRFCS
YSWCCYSLAKRQSWNYKDLRRN*KTC*RSRYFL
WLLLRPSIFGVICTLLGAQRKRDNLWTHSVHQ*
MPYCFCCIRSCLFPNSRDFGCHESRLWNSTQSFA
GRWRNDQQQNSYAATSRHSVYTSSEALNARNHC
TGCGYGGRGCRRSRRMESRTRGFVCRHDGAV*T
SD*CGGK*NSLFYMEESCDEVNGLGYNSISRKWY
SIKPTNSWIPKM*AFYIMKEPSNSVS*CNDTIH
RL*FYL*ATCCMTLQVDLWLKIKKMQQKECYRN
IWWFFFFLNIHS*GWASYLWG*PPPLP*HPAPFP
LRCRKNSDPYHWNLPSNILKHFWTRI*VSA*HI
LD*KVITNLLKISSSLLLTDTLKVFFST*LKTA
TSSLNV*IETSTKLLK*TFSVLTAWIFF*KVICQ
N*NPSDVFHGPTNYNDFLSGSYRKRYFLFSSIF
PFYIFYFVCITYMPIYFIH*G*PIYKLRAHYIQ
KVLTGLVLSEPLCI*ICWKTAVYIFGQRLCIIFT
RRIFFLTSQHLKFMFYVNKRKYTLL*LQLYFLS
LTFLFNCLSLKKEETVEYYSKYCFQTQAIIQIV
IFLLN*F*TYFGSY*GDKRMSKKLNT*VEKNIEI
KPRISFSSNVINC**EIAIWDDRITSA*YLIIT
ERRFIITNTFQ*NQEFLKIFNVTYYKKLPNPAS
*HQFLKIS*NYFVL**TVKKRLPPNYFFQ*VLNG
KTFISYYKRFCFVWNQW*LY*LF*LCCF*FIES
ARFY*CSHHLSDINIIERYCEMITLWQGYF*T*
MFLQK*VEFIVNNCESHCSNNFKITLIFL*IGRF
INV*NCTH*YLMTNLLKIN*PLVL

Frame 1

RSADARGLDLWTRHLPLPLPPPSPRKPAAIAGR
PEAGFMAASKKAVLGPLVGAVDQGTSSTRFLVF
NSKTAELLSHHQVEIKQEFPREGWVEQDPKEILH
SVYECIEKTCEKLGQLNIDISNIKAIGVSNQRE
TTVVWDKITGEPLYNAVVWLDLRTQSTVESLSK
RIPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVR
KVQKAVEEKRALFGTIDSWLIWSLTGGVNGGVH
CTDVTNASRTMLFNIHSLEWDKQLCEFFGIPME
ILPNVRSSSEIYGLMKISHSVKAGALEGVPISGC
LGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNT
GHKCVFSDHGLLTTVAYKLGRDKPVYYALEGSV
AIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSY
GCYFVPAFSGLYAPYWEPSARGIICGLTQFTNK
CHIAFAALEAVCFQTREILDAMNRDCGIPLSHL
QVDGGMTSNKILMQLQADILYIPVVKPSMPETTA
LGAAMAAGAAEGVGVWSLEPEDLSAVTMERFEP
QINAEESEIRYSTWKKAVMKSMGWVTTQSPESG
IP*NLPTHGFPRCELFT**KNPAILSLNAMTLFI
DFDFIYKPLAA*PSK*TCGLK*RKCSKKNAIEI
FGGFFFF*TSTVKVGPATFGADPLHCHNILLHS
L*DVGRIRILTIGIFHRTYSNTFGPGFESLHDIY
LIKRLLLTC*KSAALCF*QTP*KSSFLHS*RQQ
HLH*MFE*KPLLNY*NRHLVFSQLGYFSEKLFA
KTEILQMFSMVPLIIMTFCLDLIGKDTFFFLPSF
LFIFFTLYV*HTCLYILYTEGSPFIN*EHIIFR
RF*QGWS*VNHCVYKYVGKQLYTFLGNGYA*YL
PGEFFS*QANI*NLCFMSIKENILYCDFNYISYP
LHFYLIVLA*KKKKLWNTTVNIVFKHKQ*FK*L
FFF*INFRHILDPIEGIRGCQKS*IPK*KKI*K
*SQESLSVQMLSIVNKKLLSGMTELPLLSISL*L
KEGLSLQIPSNETKNFSKYLMSHIIRSYLILLL
NINF*KYLKITLFCSKQ*RKDCLLIIFFNEC*M
GKHLYLTIKGSVLFGINGSFIDCSDCAVSNLLNL
LGFIDAATT*VT*IL*KGTVK*SLCGRGTFKHK
CFYKSRLSSL*IIVKATVQIILRLH*FFYKLED
L*MFEIVHIDI**QIYLK*IDPLFL

Frame 2

VQRTRAASISGLVTCPSPSRRRHPGNRPQSPAD
LKLVSWQPQRRQFWGHWWGRWTRAPVRRAFWFS
IQKQLNYLVIIK*K*NKSSQEKDGWNRTLRKFY
ILSMSV*RKHVRNLDSSILIFPT*KLLVSATRGK
PL*SGTR*LESLSTMLWCGLI*EPSLPLRVLVK
EFQEIITLSSPRQAFHLALTSVQ*NFVGSLTM*
EKFKRPLKKNELFLGLLIHGLFGV*QEESMEVST
VQM*QMQVGLCFSTFILWNGINNSANFLEFQWK
FFQMSGVLLRSMA**KSLIA*KLGPWKVCQYLG
V*GTSLLHWWDKCASRLDKPKIRMEQDVSYYVIQ
AISVYFLIMAFSPQWLTNLAETNQYIMLWKVL*
L*LVLLFAG*ETILEL*RPQKKLKNLLKK*VLL
MAATSSQHFRGYMHLIGSPAQEG*SVDSLSSPIN
AILLLLH*KLFVSKLERFWMP*IETVEFHSVIC
R*MEE*PATKFLCSYKQTFCIYQ**SPQCPKPL
HWVRLWRQGLQKESAYGVSNPRICLPSRWSGLNL
RLMRRKVKFVILHGRKL**SQWVGLQLNLQKVV
FHKTYQLMDSQDVSFLHNERTQQFCLLMQ*HYS
*TLILFISHLLHDPPSRPVA*NKENAAKRML*KY
LVVFFFFKHPQLRLGQLPLGLTPSIAITSCSIP
SKM*EEFGSLPLESSIEHTQTLLDQDLSLCMTY
T*LKGYY*PVKNQQLFAFNRHPKSLLFYIVEDSN
IFTECLNRNLY*IIKIDI*CSHSLDIFLKSYLP
KLKSFRCFPWSH*L**LSVWIL*EKILSFFFHL
SFLYFLLCMYNIHAYIFYTLRVAHL*IKSTLYSE
GSNRAGLK*TTVYINMLENSCIHFWATVMHNIY
QENFFLNKPTFKIYVLCQ*KKIYFIVTSTIFLI
PYIFI*LS*LKKRRNCGILQ*ILFSNTSNNSNSY
FSFELILDIFWILLRG*EDVKKVKYLSRKKYRN
KAKNLFQFKCYQLLIRNCYLG*QNYLCLVSHYN
*KKVYHYKYLPMKPRISQNI*CHIL*EVT*SCFL
TSIFKNILKLLCFVVNSEEKIAS*LFFSMSAEW
ENIYILL*KVLFCLESMVALLTVLIVLFLIY*I
C*VLLMQPPLK*HKYYRKVL*NDHFVAGVLLNIN
VSTKVG*VHCK*L*KPLFK*F*DYINFSINWKI
YKCLKLYTLIFNDKFT*NKLTPCS

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