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Sequences

Sequence NM_032981

GTGAGTGTTGCCCAGAGTTAAAGGGAATATCAAGGATGGTGGCAGAATTAAAGGGCAAACTTACCTTCCATCCCAGGTCTAGTATTCAGTCCCCCTTCCT
CCCACTCTCCACCCTACTGCGTGCTCTTACTTATTCTGTTGGAACCCAGTGTAGCTTCCTGAGATTTAAAATATAGGAAGACTCAAAACTATGTTACTTC
TTGGAATATAGATAATTCAGTACTGATTTAAATAACAACTGAATAGCAAGGACCTTCTGGAACATAATCTTACATTCACAAAATCACCTGCTAAGAAGCT
GACTAATGCATTAAGCAAGTCCCTGAGCTGTGCTTCCAGCCGTGAACCTTTGCACCCCATGTTCCCAGATCAGCCTGAGAAGCCACTCAACTTGGCTCAC
ATCGTGCCTCCCAGACCTGTAACCAGCATGAACGACACCCTGTTCTCCCACTCTGTTCCCTCCTCAGGAAGTCCTTTTATTACCAGGAGCATGCTTGAGA
GTTCAAACCGGCTTGATGAAGAACACAGGCTAATTGCCAGGTATGCGGCAAGGCTGGCAGCAGAGTCCTCTTCGTCTCAGCCACCTCAGCAGAGAAGTGC
TCCTGACATCTCTTTCACCATCGATGCGAATAAGCAGCAAAGGCAGCTGATTGCTGAGCTAGAAAACAAGAACAGAGAAATCTTACAGGAGATCCAGAGA
CTTCGGCTAGAGCATGAACAAGCTTCTCAGCCCACGCCAGAGAAGGCACAGCAAAACCCCACCCTGCTGGCAGAACTCCGGCTCCTCAGACAGCGCAAAG
ATGAGCTGGAACAGAGAATGTCTGCTCTCCAGGAGAGCCGGAGAGAGCTAATGGTCCAGTTGGAGGGTCTCATGAAGCTACTAAAGGAAGAAGAACTGAA
GCAGGGAGTAAGTTATGTCCCCTACTGCAGGTCTTAACTAACAGTGGAGGGGCCTGCCGACCTGCGGTTTTCTCATTGCTTTTGCTCTAATGTATGTTCA
TGCTTCAGTTTGGAAAGAGAAAAAAGTCATACTAATTTGCTTCTTTTTCAATGTAGTGCTTGAATTGAGATATATAAATTTAGCATTTTTTATAACTATC
ACTACTATCCACATCAAAAGAAGAACTATGACATCTTTTAGAAAAGGGAACGAATTGTCATTTATTGGAAACATTTTAGATCCCCAGAGGTATAAGTTTC
AAACCAGTCTTAGCTTTTCAAGTTGTTGATCAGACCCTTCTCTTAACAGAGAGATACCACAGTCACTAGAGATACCCTGAGGTTCATGTCATCCCAAAAC
CCACAGCACTCAGAAGCTAACCTCTACACCCACTCACACTGTGAGTATTCAGTTCGGTTTCATTTTACTGAAAACCTGTGAAACCTCTTTTTATAAAAAT
CAGGCAATTAAATCCCTTTTCATCACACAATTATTGAGCCTTGTTCCCCATGGCTCACCAAAATGTGCTCAATTTTGTGAGAGAAAGACTGTACTCCATA
ACTGACTATTCACGTCCCATCTTTTTGGCTCTTCCCCAAAGCAGAATCCTTACTGTTGGTTGACAGTAATCTCTTTTTAAAAAGTAACTCTCAGCTTTTT
CCTTAGCACCAGAGCCTTTCGGCTCCGGGAGACGAGAGGGTCATTACATACTTTTTTTTTTTTCTGGAAATAGGGGCATTGTGACTTTATAGCCTAAACT
GGAGCTGTCTGAACCTGTGGTCAGGCTCAAGAGCCAGCAGGGGGAGCAGCAAACTCAAAAAAAAAAACAAATTAAATTAAATTAAATTAAATTAAATAGA
AGCAAAATAAAAGCAGCTTTAATTTCAAGTGCATGTACCACGCTATGTATGACAATATATCCCACTCACTAGCATTATTTAAAAGTTTCACATTATTTCC
ATGGATCAATTAGAACCACAACCTGTCCAATTTCAACGTATCTTTCATTTCTTCTGTATGCTCTTTTCTATTATTCATTATGTGTGTTTGTGTGTAACAA
AGAATGTTTGGAAAATGCTGGACACATTTTTACCCTTCATTCCCATGGTCTGTAAAAAAGGAAAGTGTAAAATCAATCTGTAATGTCAGACAATAAAGAT
AATGTATTACATTATTTTGTATTTTGTGAAAAAAATTACTTTACTAAATTAAAGTCAAATTTTAACAGAAGACAGTCCCCC
  • refseq_DTNA.F1 (forward primer)
  • refseq_DTNA.R1 (reverse primer)
  • Single exon skipping

Frame 0

VSVAQS*REYQGWWQN*RANLPSIPGLVFSPPS
SHSPPYCVLLLILLEPSVAS*DLKYRKTQNYVTS
WNIDNSVLI*ITTE*QGPSGT*SYIHKITC*EA
D*CIKQVPELCFQP*TFAPHVPRSA*EATQLGS
HRASQTCNQHERHPVLPLCSLLRKSFYYQEHA*E
FKPA**RTQANCQVCGKAGSRVLFVSATSAEKC
S*HLFHHRCE*AAKAADC*ARKQEQRNLTGDPE
TSARA*TSFSAHAREGTAKPHPAGRTPAPQTAQR
*AGTENVCSPGEPERANGPVGGSHEATKGRRTE
AGSKLCPLLQVLTNSGGACRPAVFSLLLL*CMF
MLQFGKRKKSY*FASFSM*CLN*DI*I*HFL*LS
LLSTSKEEL*HLLEKGTNCHLLETF*IPRGISF
KPVLAFQVVDQTLLLTERYHSH*RYPEVHVIPK
PTALRS*PLHPLTL*VFSSVSFY*KPVKPLFIKI
RQLNPFSSHNY*ALFPMAHQNVLNFVRERLYSI
TDYSRPIFLALPQSRILTVG*Q*SLFKK*LSAF
SLAPEPFGSGRREGHYILFFFSGNRGIVTL*PKL
ELSEPVVRLKSQQGEQQTQKKKQIKLN*IKLNR
SKIKAALISSACTTLCMTIYPTH*HYLKVSHYF
HGSIRTTTCPISTYLSFLLYALFYYSLCVFVCNK
ECLENAGHIFTLHSHGL*KRKV*NQSVMSDNKD
NVLHYFVFCEKNYFTKLKSNFNRRQSP

Frame 1

*VLPRVKGNIKDGGRIKGQTYLPSQV*YSVPLP
PTLHPTACSYLFCWNPV*LPEI*NIGRLKTMLL
LGI*IIQY*FK*QLNSKDLLEHNLTFTKSPAKKL
TNALSKSLSCASSREPLHPMFPDQPEKPLNLAH
IVPPRPVTSMNDTLFSHSVPSSGSPFITRSMLE
SSNRLDEEHRLIARYAARLAAESSSSQPPQQRSA
PDISFTIDANKQQRQLIAELENKNREILQEIQR
LRLEHEQASQPTPEKAQQNPTLLAELRLLRQRK
DELEQRMSALQESRRELMVQLEGLMKLLKEEELK
QGVSYVPYCRS*LTVEGPADLRFSHCFCSNVCS
CFSLEREKSHTNLLLFQCSA*IEIYKFSIFYNY
HYYPHQKKNYDIF*KRERIVIYWKHFRSPEV*VS
NQS*LFKLLIRPFS*QRDTTVTRDTLRFMSSQN
PQHSEANLYTHSHCEYSVRFHFTENL*NLFL*K
SGN*IPFHHTIIEPCSPWLTKMCSIL*EKDCTP*
LTIHVPSFWLFPKAESLLLVDSNLFLKSNSQLF
P*HQSLSAPGDERVITYFFFFLEIGAL*LYSLN
WSCLNLWSGSRASRGSSKLKKKNKLN*IKLN*IE
AK*KQL*FQVHVPRYV*QYIPLTSII*KFHIIS
MDQLEPQPVQFQRIFHFFCMLFSIIHYVCLCVT
KNVWKMLDTFLPFIPMVCKKGKCKINL*CQTIKI
MYYIILYFVKKITLLN*SQILTEDSP

Frame 2

ECCPELKGISRMVAELKGKLTFHPRSSIQSPFL
PLSTLLRALTYSVGTQCSFLRFKI*EDSKLCYF
LEYR*FSTDLNNN*IARTFWNIILHSQNHLLRS
*LMH*ASP*AVLPAVNLCTPCSQISLRSHSTWLT
SCLPDL*PA*TTPCSPTLFPPQEVLLLPGACLR
VQTGLMKNTG*LPGMRQGWQQSPLRLSHLSREV
LLTSLSPSMRISSKGS*LLS*KTRTEKSYRRSRD
FG*SMNKLLSPRQRRHSKTPPCWQNSGSSDSAK
MSWNRECLLSRRAGES*WSSWRVS*SY*RKKN*
SRE*VMSPTAGLN*QWRGLPTCGFLIAFALMYVH
ASVWKEKKVILICFFFNVVLELRYINLAFFITI
TTIHIKRRTMTSFRKGNELSFIGNILDPQRYKF
QTSLSFSSC*SDPSLNREIPQSLEIP*GSCHPKT
HSTQKLTSTPTHTVSIQFGFILLKTCETSFYKN
QAIKSLFITQLLSLVPHGSPKCAQFCERKTVLH
N*LFTSHLFGSSPKQNPYCWLTVISF*KVTLSFF
LSTRAFRLRETRGSLHTFFFFWK*GHCDFIA*T
GAV*TCGQAQEPAGGAANSKKKTN*IKLN*IK*
KQNKSSFNFKCMYHAMYDNISHSLALFKSFTLFP
WIN*NHNLSNFNVSFISSVCSFLLFIMCVCV*Q
RMFGKCWTHFYPSFPWSVKKESVKSICNVRQ*R
*CITLFCIL*KKLLY*IKVKF*QKTVP

Sequence NM_032980

GTGAGTGTTGCCCAGAGTTAAAGGGAATATCAAGGATGGTGGCAGAATTAAAGGGCAAACTTACCTTCCATCCCAGGTCTAGTATTCAGTCCCCCTTCCT
CCCACTCTCCACCCTACTGCGTGCTCTTACTTATTCTGTTGGAACCCAGTGTAGCTTCCTGAGATTTAAAATATAGGAAGACTCAAAACTATGTTACTTC
TTGGAATATAGATAATTCAGTACTGATTTAAATAACAACTGAATAGCAAGGACCTTCTGGAACATAATCTTACATTCACAAAATCACCTGCTAAGAAGCT
GACTAATGCATTAAGCAAGTCCCTGAGCTGTGCTTCCAGCCGTGAACCTTTGCACCCCATGTTCCCAGATCAGCCTGAGAAGCCACTCAACTTGGCTCAC
ATCGTGCCTCCCAGACCTGTAACCAGCATGAACGACACCCTGTTCTCCCACTCTGTTCCCTCCTCAGGAAGTCCTTTTATTACCAGGAGCTCTCCTCCCA
AGGACAGTGAAGTAGAGCAGAACAAACTGCTGGCTAGGGCTGCTCCAGCTTTTCTGAAGGGCAAAGGCATGCTTGAGAGTTCAAACCGGCTTGATGAAGA
ACACAGGCTAATTGCCAGGTATGCGGCAAGGCTGGCAGCAGAGTCCTCTTCGTCTCAGCCACCTCAGCAGAGAAGTGCTCCTGACATCTCTTTCACCATC
GATGCGAATAAGCAGCAAAGGCAGCTGATTGCTGAGCTAGAAAACAAGAACAGAGAAATCTTACAGGAGATCCAGAGACTTCGGCTAGAGCATGAACAAG
CTTCTCAGCCCACGCCAGAGAAGGCACAGCAAAACCCCACCCTGCTGGCAGAACTCCGGCTCCTCAGACAGCGCAAAGATGAGCTGGAACAGAGAATGTC
TGCTCTCCAGGAGAGCCGGAGAGAGCTAATGGTCCAGTTGGAGGGTCTCATGAAGCTACTAAAGACTCAGGGGGCAGGCTCTCCCCGCTCCTCCCCCAGC
CACACCATCAGCAGGCCAATTCCCATGCCCATCCGGTCAGCGTCAGCCTGCTCCACCCCGACGCACACGCCGCAGGACTCCCTCACAGGAGTAGGGGGAG
ATGTACAAGAGGCATTTGCACAAAGTTCAAGAAGAAACTTAAGGAATGACTTGCTAGTGGCTGCAGATTCCATCACTAACACTATGTCCTCTCTTGTGAA
AGAGCTGAATTCTGAGGTTGGGAGTGAAACAGAGAGTAATGTGGATTCTGAATTTGCACGGACTCAGTTTGAGGATCTTGTTCCCTCACCAACCTCTGAA
AAGGCTTTTCTAGCGCAAATCCATGCCCGAAAACCTGGGTACATTCACAGTGGAGCTACCACAAGTACCATGCGTGGCGACATGGTTACGGAGGATGCAG
ATCCCTATGTGCAGCCTGAAGATGAAAACTATGAAAATGACTCTGTCCGGCAGCTGGAGAATGAGCTCCAGATGGAGGAATACCTGAAACAGAAGCTGCA
AGATGAAGCTTATCAGGTCAGCTTGCAAGGTTGAATGCAATATCCTTTTATCACACTCCTCTCAAGCAAGCTATAGTCAGACAGATGATGAAAGTAACAT
GAAAACTGGTGATGATGGAGAGCCCTGTGGCCACACAGAGGAGGAAGACAGCAGCCTGGCAGCAGCCTCACCGAAGAGAGGAACCACCACACCCAGCAGC
TCCTGACAGACCCCCACCCCTAAAGATGTGTCCTGATGACTATAGTGCAGCTAACTTTTTGTTCTCAGATTTGTAGTGCATAGGTGTGTGTTTCAAGAAG
GAAAAAAAAAGACTTCTGTTCAAAGTTAACTTATCAGCTACATCCTCTGTAACGTGGTTCATCCCTGGTTAAAAAGCAAACAAACACAGGCTGAAAACCC
ATGCTGCTGTTATACACAATGGCAGTATTAACAAGCATTTTAAACCTTTGCACATGATATTGAACCTGTTCAGTTTACAATGACAATATTAATACTGTTT
ATAGCTAGAAGTTTGATTTCTGAATTCTTTGAGATTTTAGCAAAACAGTTTATTATACACTGTACATTTTTTTCACAGCAATTGGAAAAAAACAACCACT
TGCAATCATTCAATAACCCTGAAGAATTTGGTTCCTGAGTGTACAAACTCAGAGCCCGGAAGCCAAGAAGGGTCCTTGGCCTGCACGGTCTGTAGTTGAC
TCCAAGTCTCTGTGAGCAGTGACTTGAACCAAACACACCAGGAATAATCCATTCTTTGGGGCCTCTTTCCAACTCGAGGTTGTTTTCTTTCAAGATACTC
TAATCAGCCATAGAATTTAGTGTAAATATTTTTTTTTCCAAATAGATATCATATTCAAAAAAGGCAGCATTCAAATTATATAGAATCTAGTTTTTAAAAT
CAGCACAGATCTTCTTAAAAACTGTGAACTATGTTTTGAAATACTCGTTACTAAAGCTGTTTATAAACCACAGGTGCCATAAGATCCCCAAACGGACTAA
AGTTATCTCTGCTCTTCCATGGTCTTGTTCCTCTCGTTTTGGCTTTAGGAAGCATGTCTTTAACAGCACCGCTCGTTCACAAGTTCCCCCATCAAGTTGT
TTGGAGGCCTTCAGCTTTAAATGTACAGGCTTAAAGTGCGCTTGCAAACGTTTGCTCTCCTTTTTTTCTGAATGTTGATTGCCTTAGCTGGCCACCTGGT
GTTCTGCATGTAGCCTTCTGTGGTCATGTGAAAGGAGACAGGCTCTTCTAAGTTGAGTTGGGATTTTTGCACTCAGTGAAAAGCTGAAGTGCAAAAGAGC
TATCAAAGACAAGAGGATAAAAGACTGGGATAGTCTTTTCCAAGGACCCTCTTTAGAGGGCCCTAAAGACCTCCTTTGGGAATTCTGGGGAAAAAGAAAA
AGTAATCTTCTACTTGCTTCAAGATTTGATTTTTTTAAAAAAGCCTGCGACCTATTCAATACATTATGCTTAAATTAGCAGTTTCTCTGGAATTCCTGTC
TCTCCTTTAAAAGAAAGGAGAGAACATTTTAGAACAATAGTTCTCAAAGTGTGTTCCCCGGACAAGCAGCATCTGCAACACTTAGGAAGGTCTTCGAAAT
ACTAATTTGTAAGCCCCACCTCAGGCCTACTGAATCAGAAGCTCTGGGGGTTGGGTCCAGAAGTCTGTTTTAGTCAACCCTCTAGGTGATTCTGATGCTC
GCTAAAGGTTGAGAACTACTGCTTTAGAATGAAGTCGTATAATAAAGTCTCTGAAAAGGCCTTATTCAGAATAAGCAAGAAAGGTTCTGTGATTCACTTT
TGCTTCTGGGGCTGGCAAAAACCTTCTCTGAACCCACACACCAAGTTCGTAGTTGGTAGGTGCCCAGCCAAGTCCTGACATCTTCATGCCCCCTCTGCAG
AGGGCGGCTGTACGATGTTCACATGTCTGCGTTTGGTCAGACATCATCTCCTTGGCTGCCCTTTGAAACCAAATCACTTGCCTTGGGGATAAAGTGCTCA
ATTGGCATTAGTGAGAAGCCCATCCTATCCCTTGACATACTTAATCATATATCTCTCCAGAGAACTCACCTGACAAATGTCTCTGAGCACAGGCTGACAC
CAAAGTGGCACAACTGCACAGTTCTCAGATTTCTTTGCACAGATTGATTTTTATTGCGGGTTTTGTTGGGGTGTCTTAATGTTCATCTCTTTTCCACTGC
CCATCCTCTGTGAACCCATACCTCTCTAGATGGAGCAGGTGGCCACTGGTGCCTCATACTCAGTATTGAAAACCACTACATCCCAGCTACCTATAATGCT
GTCAGCTCAAAATCATAGCCAGGTAGTTCTTGAACTCAGAACTTAAATCCTGCACGTGGCACTCCACCACTGACTGGACCGAGCTGGCATATGTTGTTTC
TTTGTGTTTCTACATCAAAATGTTCGTCTAAGATTTGAACTGTTCTGCTGATAACCTTCCCCGTTGTCATAGCTATTTCATTGCCAACCAACTCCATCAC
ATGGTTGTTGATATCGTCATATAAAGCCATTGCAAGGACTCTGGAAACTGCCGCCAATGACCAATTTCTGACTAACCAGCCACCTTTTCTCTCTCTTAGC
TCCACGTCAGCACTGAGACCAGACTCGAGCACCCCTGTCCTGTAAGCGAGACAAAATGGCGTGTGTTATTTTGGGGTTTTGTGTTTTTTGGTGGGTTTCT
TTCCTTGGCTCTCCAGATTTACTTTTGGGGCCTGTTCTAAGTGCAAACCCAGCAAGTTTCACTTGTCCTGTCCATTAGATACAACTACATCTTGCGGGGG
TTGTTTCTTTCTTGTTCCACAATGAATTGCACATCCATCTCCATCAGAGCTGATAGCCTGTTAATAAGCACTGGTCTAACACAGCCAACCCTCCTCCACA
GCGCCATATTAATGGAGGAGGGGAGGAAGGTGAAATCTACTGCATGGGATTCAGGAAACAGTTGTGGTTGGTCAGGACGGAAGTTGGGGTAAGTTTGGTT
GGTCAGAGGGAGTTGTGCTGGAGATTGTGAAAAATGGGTTCTTGAATGATCTACTATAAGGCAGGGAAGGTTCATTTGTAAGTAGTAATGTGAACTGAAT
TGCATTAAGAGTGTGTGGCCTTTGTTGTGATATACTATGTATTTTCTTATATGCATGAGCCAAACTGTTGCATCATAATTTAGCACTGATGTCTGCTTTT
ATTTTGATCATCTTTGTCCACCCTTATTAGTTCTTGGCTGTTAACCGTAGATAGATCTTGTAAATCCAGCAACCTTTGGTTGCTGCATTCCCCTTGGTTC
GATTCCACGCAAGGAGCCACAAGTGAGAACTCCACTGTCCTTAGAAGAAAGGGCATTTTTACTTTTGAACCAAAAAGAGAAAAAAAAATCAGAAGTGTTG
CATCTTGAGGCGAATTAACTGTAAGACATTTTTAATTATGACTACTGCAATTTGACACCATTTGAAATAATCAATTCAGAGACACTAAAGATTTCACAAT
ATTCATTGGTATTGTAAAAAAAAAATACTATTGTATGGATTTTTGTATTGCTGTTAAGTATTGTTTTGTGTGTGTGTGTGTGTGTGTGTGTTGGAACCTC
CTGGGGACATGTTATATTTTGAAGTGATTAAACTATTTAATTGTGTGTCTATATTTTGGAGTGGAATAATTTCTTCATTAAAAAATGTTTTTAAAAACAC
TA
  • refseq_DTNA.F1 (forward primer)
  • refseq_DTNA.R1 (reverse primer)
  • Single exon skipping

Frame 0

VSVAQS*REYQGWWQN*RANLPSIPGLVFSPPS
SHSPPYCVLLLILLEPSVAS*DLKYRKTQNYVTS
WNIDNSVLI*ITTE*QGPSGT*SYIHKITC*EA
D*CIKQVPELCFQP*TFAPHVPRSA*EATQLGS
HRASQTCNQHERHPVLPLCSLLRKSFYYQELSSQ
GQ*SRAEQTAG*GCSSFSEGQRHA*EFKPA**R
TQANCQVCGKAGSRVLFVSATSAEKCS*HLFHH
RCE*AAKAADC*ARKQEQRNLTGDPETSARA*TS
FSAHAREGTAKPHPAGRTPAPQTAQR*AGTENV
CSPGEPERANGPVGGSHEATKDSGGRLSPLLPQ
PHHQQANSHAHPVSVSLLHPDAHAAGLPHRSRGR
CTRGICTKFKKKLKE*LASGCRFHH*HYVLSCE
RAEF*GWE*NRE*CGF*ICTDSV*GSCSLTNL*
KGFSSANPCPKTWVHSQWSYHKYHAWRHGYGGCR
SLCAA*R*KL*K*LCPAAGE*APDGGIPETEAA
R*SLSGQLARLNAISFYHTPLKQAIVRQMMKVT
*KLVMMESPVATQRRKTAAWQQPHRREEPPHPAA
PDRPPPLKMCPDDYSAANFLFSDL*CIGVCFKK
EKKRLLFKVNLSATSSVTWFIPG*KANKHRLKT
HAAVIHNGSINKHFKPLHMILNLFSLQ*QY*YCL
*LEV*FLNSLRF*QNSLLYTVHFFHSNWKKTTT
CNHSITLKNLVPECTNSEPGSQEGSLACTVCS*
LQVSVSSDLNQTHQE*SILWGLFPTRGCFLSRYS
NQP*NLV*IFFFPNRYHIQKRQHSNYIESSF*N
QHRSS*KL*TMF*NTRY*SCL*TTGAIRSPNGL
KLSLLFHGLVPLVLALGSMSLTAPLVHKFPHQVV
WRPSALNVQA*SALANVCSPFFLNVDCLSWPPG
VLHVAFCGHVKGDRLF*VELGFLHSVKS*SAKE
LSKTRG*KTGIVFSKDPL*RALKTSFGNSGEKEK
VIFYLLQDLIFLKKPATYSIHYA*ISSFSGIPV
SPLKERREHFRTIVLKVCSPDKQHLQHLGRSSK
Y*FVSPTSGLLNQKLWGLGPEVCFSQPSR*F*CS
LKVENYCFRMKSYNKVSEKALFRISKKGSVIHF
CFWGWQKPSLNPHTKFVVGRCPAKS*HLHAPSA
EGGCTMFTCLRLVRHHLLGCPLKPNHLPWG*SAQ
LALVRSPSYPLTYLIIYLSRELT*QMSLSTG*H
QSGTTAQFSDFFAQIDFYCGFCWGVLMFISFPL
PILCEPIPL*MEQVATGASYSVLKTTTSQLPIML
SAQNHSQVVLELRT*ILHVALHH*LDRAGICCF
FVFLHQNVRLRFELFC**PSPLS*LFHCQPTPS
HGC*YRHIKPLQGLWKLPPMTNF*LTSHLFSLLA
PRQH*DQTRAPLSCKRDKMACVILGFCVFWWVS
FLGSPDLLLGPVLSANPASFTCPVH*IQLHLAG
VVSFLFHNELHIHLHQS**PVNKHWSNTANPPPQ
RHINGGGEEGEIYCMGFRKQLWLVRTEVGVSLV
GQRELCWRL*KMGS*MIYYKAGKVHL*VVM*TE
LH*ECVAFVVIYYVFSYMHEPNCCIII*H*CLLL
F*SSLSTLISSWLLTVDRSCKSSNLWLLHSPWF
DSTQGATSENSTVLRRKGIFTFEPKREKKIRSV
AS*GELTVRHF*L*LLQFDTI*NNQFRDTKDFTI
FIGIVKKKYYCMDFCIAVKYCFVCVCVCVCWNL
LGTCYILK*LNYLIVCLYFGVE*FLH*KMFLKT
L

Frame 1

*VLPRVKGNIKDGGRIKGQTYLPSQV*YSVPLP
PTLHPTACSYLFCWNPV*LPEI*NIGRLKTMLL
LGI*IIQY*FK*QLNSKDLLEHNLTFTKSPAKKL
TNALSKSLSCASSREPLHPMFPDQPEKPLNLAH
IVPPRPVTSMNDTLFSHSVPSSGSPFITRSSPP
KDSEVEQNKLLARAAPAFLKGKGMLESSNRLDEE
HRLIARYAARLAAESSSSQPPQQRSAPDISFTI
DANKQQRQLIAELENKNREILQEIQRLRLEHEQ
ASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMS
ALQESRRELMVQLEGLMKLLKTQGAGSPRSSPS
HTISRPIPMPIRSASACSTPTHTPQDSLTGVGG
DVQEAFAQSSRRNLRNDLLVAADSITNTMSSLVK
ELNSEVGSETESNVDSEFARTQFEDLVPSPTSE
KAFLAQIHARKPGYIHSGATTSTMRGDMVTEDA
DPYVQPEDENYENDSVRQLENELQMEEYLKQKLQ
DEAYQVSLQG*MQYPFITLLSSKL*SDR**K*H
ENW**WRALWPHRGGRQQPGSSLTEERNHHTQQ
LLTDPHP*RCVLMTIVQLTFCSQICSA*VCVSRR
KKKDFCSKLTYQLHPL*RGSSLVKKQTNTG*KP
MLLLYTMAVLTSILNLCT*Y*TCSVYNDNINTV
YS*KFDF*IL*DFSKTVYYTLYIFFTAIGKKQPL
AIIQ*P*RIWFLSVQTQSPEAKKGPWPARSVVD
SKSL*AVT*TKHTRNNPFFGASFQLEVVFFQDT
LISHRI*CKYFFFQIDIIFKKGSIQII*NLVFKI
STDLLKNCELCFEILVTKAVYKPQVP*DPQTD*
SYLCSSMVLFLSFWL*EACL*QHRSFTSSPIKL
FGGLQL*MYRLKVRLQTFALLFF*MLIALAGHLV
FCM*PSVVM*KETGSSKLSWDFCTQ*KAEVQKS
YQRQEDKRLG*SFPRTLFRGP*RPPLGILGKKK
K*SSTCFKI*FF*KSLRPIQYIMLKLAVSLEFLS
LL*KKGENILEQ*FSKCVPRTSSICNT*EGLRN
TNL*APPQAY*IRSSGGWVQKSVLVNPLGDSDA
R*RLRTTALE*SRIIKSLKRPYSE*ARKVL*FTF
ASGAGKNLL*THTPSS*LVGAQPSPDIFMPPLQ
RAAVRCSHVCVWSDIISLAAL*NQITCLGDKVL
NWH**EAHPIP*HT*SYISPENSPDKCL*AQADT
KVAQLHSSQISLHRLIFIAGFVGVS*CSSLFHC
PSSVNPYLSRWSRWPLVPHTQY*KPLHPSYL*C
CQLKIIAR*FLNSELKSCTWHSTTDWTELAYVVS
LCFYIKMFV*DLNCSADNLPRCHSYFIANQLHH
MVVDIVI*SHCKDSGNCRQ*PISD*PATFSLS*
LHVSTETRLEHPCPVSETKWRVLFWGFVFFGGFL
SLALQIYFWGLF*VQTQQVSLVLSIRYNYILRG
LFLSCSTMNCTSISIRADSLLISTGLTQPTLLH
SAILMEEGRKVKSTAWDSGNSCGWSGRKLG*VWL
VRGSCAGDCEKWVLE*STIRQGRFICK**CELN
CIKSVWPLL*YTMYFLICMSQTVAS*FSTDVCF
YFDHLCPPLLVLGC*P*IDLVNPATFGCCIPLGS
IPRKEPQVRTPLSLEERAFLLLNQKEKKKSEVL
HLEAN*L*DIFNYDYCNLTPFEIINSETLKISQ
YSLVL*KKNTIVWIFVLLLSIVLCVCVCVCVGTS
WGHVIF*SD*TI*LCVYILEWNNFFIKKCF*KH

Frame 2

ECCPELKGISRMVAELKGKLTFHPRSSIQSPFL
PLSTLLRALTYSVGTQCSFLRFKI*EDSKLCYF
LEYR*FSTDLNNN*IARTFWNIILHSQNHLLRS
*LMH*ASP*AVLPAVNLCTPCSQISLRSHSTWLT
SCLPDL*PA*TTPCSPTLFPPQEVLLLPGALLP
RTVK*SRTNCWLGLLQLF*RAKACLRVQTGLMK
NTG*LPGMRQGWQQSPLRLSHLSREVLLTSLSPS
MRISSKGS*LLS*KTRTEKSYRRSRDFG*SMNK
LLSPRQRRHSKTPPCWQNSGSSDSAKMSWNREC
LLSRRAGES*WSSWRVS*SY*RLRGQALPAPPPA
TPSAGQFPCPSGQRQPAPPRRTRRRTPSQE*GE
MYKRHLHKVQEET*GMTC*WLQIPSLTLCPLL*
KS*ILRLGVKQRVMWILNLHGLSLRILFPHQPLK
RLF*RKSMPENLGTFTVELPQVPCVATWLRRMQ
IPMCSLKMKTMKMTLSGSWRMSSRWRNT*NRSC
KMKLIRSACKVECNILLSHSSQASYSQTDDESNM
KTGDDGEPCGHTEEEDSSLAAASPKRGTTTPSS
S*QTPTPKDVS**L*CS*LFVLRFVVHRCVFQE
GKKKTSVQS*LISYILCNVVHPWLKSKQTQAENP
CCCYTQWQY*QAF*TFAHDIEPVQFTMTILILF
IARSLISEFFEILAKQFIIHCTFFSQQLEKNNH
LQSFNNPEEFGS*VYKLRARKPRRVLGLHGL*LT
PSLCEQ*LEPNTPGIIHSLGPLSNSRLFSFKIL
*SAIEFSVNIFFSK*ISYSKKAAFKLYRI*FLK
SAQIFLKTVNYVLKYSLLKLFINHRCHKIPKRTK
VISALPWSCSSRFGFRKHVFNSTARSQVPPSSC
LEAFSFKCTGLKCACKRLLSFFSEC*LP*LATW
CSACSLLWSCERRQALLS*VGIFALSEKLKCKRA
IKDKRIKDWDSLFQGPSLEGPKDLLWEFWGKRK
SNLLLASRFDFFKKACDLFNTLCLN*QFLWNSC
LSFKRKERTF*NNSSQSVFPGQAASATLRKVFEI
LICKPHLRPTESEALGVGSRSLF*STL*VILML
AKG*ELLL*NEVV**SL*KGLIQNKQERFCDSL
LLLGLAKTFSEPTHQVRSW*VPSQVLTSSCPLCR
GRLYDVHMSAFGQTSSPWLPFETKSLALGIKCS
IGISEKPILSLDILNHISLQRTHLTNVSEHRLT
PKWHNCTVLRFLCTD*FLLRVLLGCLNVHLFSTA
HPL*THTSLDGAGGHWCLILSIENHYIPATYNA
VSSKS*PGSS*TQNLNPARGTPPLTGPSWHMLF
LCVSTSKCSSKI*TVLLITFPVVIAISLPTNSIT
WLLISSYKAIARTLETAANDQFLTNQPPFLSLS
STSALRPDSSTPVL*ARQNGVCYFGVLCFLVGF
FPWLSRFTFGACSKCKPSKFHLSCPLDTTTSCGG
CFFLVPQ*IAHPSPSELIAC**ALV*HSQPSST
APY*WRRGGR*NLLHGIQETVVVGQDGSWGKFG
WSEGVVLEIVKNGFLNDLL*GREGSFVSSNVN*I
ALRVCGLCCDILCIFLYA*AKLLHHNLALMSAF
ILIIFVHPY*FLAVNRR*IL*IQQPLVAAFPLV
RFHARSHK*ELHCP*KKGHFYF*TKKRKKNQKCC
ILRRINCKTFLIMTTAI*HHLK*SIQRH*RFHN
IHWYCKKKILLYGFLYCC*VLFCVCVCVCVLEP
PGDMLYFEVIKLFNCVSIFWSGIISSLKNVFKNT

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