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Sequences

Sequence NM_032978

refseq_DTNA.F3 (forward primer)
refseq_DTNA.R3 (reverse primer)
Single exon skipping

Frame 0

DCCVLSTRGRMNTAFY*S*RLLWSLFGNV*GQI L*FSAYVVLQRKN*GACWCI*LQNQND*R*WEKR KYHGRKKTAVCRDEGSRSGSHPTLHLQNSMQA* VCSEEMQFAPGGHMECHRSIAGKCSEQPGPKH* TQRVPLRGCALHYFLPAQQTDANHSPNPCGAVHQ PPP*LPACSV*SGRPW*NFSICCQNGFSHIVWR EDHGQIKIYFLNDF*LQWGDGLWTI*PIPSGSS QTTHGSF*RSFIWLHRTVSQILFLPTEKSHVKWF LGHAYVRSSPAVSGLVASSASTSKCGKCLPSG* VFLLPQ*EYDGISLPMPTVSQLPALSGLLLEGT CRWFS*QPAPNERVHVMEITC*EAD*CIKQVPEL CFQP*TFAPHVPRSA*EATQLGSHRASQTCNQH ERHPVLPLCSLLRKSFYYQELSSQGQ*SRAEQT AG*GCSSFSEGQRDTVQPECGRQAS**TCSHRVV CQHAPEQPLMHA*EFKPA**RTQANCQVCGKAG SRVLFVSATSAEKCS*HLFHHRCE*AAKAADC* ARKQEQRNLTGDPETSARA*TSFSAHAREGTAKP HPAGRTPAPQTAQR*AGTENVCSPGEPERANGP VGGSHEATKGRRTEAGSKLCPLLQVLTNSGGAC RPAVFSLLLL*CMFMLQFGKRKKSY*FASFSM*C LN*DI*I*HFL*LSLLSTSKEEL*HLLEKGTNC HLLETF*IPRGISFKPVLAFQVVDQTLLLTERY HSH*RYPEVHVIPKPTALRS*PLHPLTL*VFSSV SFY*KPVKPLFIKIRQLNPFSSHNY*ALFPMAH QNVLNFVRERLYSITDYSRPIFLALPQSRILTV G*Q*SLFKK*LSAFSLAPEPFGSGRREGHYILFF FSGNRGIVTL*PKLELSEPVVRLKSQQGEQQTQ KKKQIKLN*IKLNRSKIKAALISSACTTLCMTI YPTH*HYLKVSHYFHGSIRTTTCPISTYLSFLLY ALFYYSLCVFVCNKECLENAGHIFTLHSHGL*K RKV*NQSVMSDNKDNVLHYFVFCEKNYFTKLKS NFNRRQSP

Frame 1

IAVC*AQGEE*TQLFIEVKGYFGVCLEMCKVKY YSFQHM*YFRGRIKGHVGAFNYKTRMIEDSGKR GNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLR FVQKKCNLHLVDIWNVIEALRENALNNLDPNTE LNVSRLEAVLSTIFYQLNKRMPTTHQIHVEQSI SLLLNFLLAAFDPEGHGKISVFAVKMALATLCGG KIMDKLRYIFSMISDSSGVMVYGRYDQFLREVL KLPTAVFEGPSFGYTEQSARSCFSQQKKVTLNG FLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVE CSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGH AGGSHSNQHQMKEYTSWKSPAKKLTNALSKSLS CASSREPLHPMFPDQPEKPLNLAHIVPPRPVTSM NDTLFSHSVPSSGSPFITRSSPPKDSEVEQNKL LARAAPAFLKGKGIQYSLNVADRLADEHVLIGL YVNMLRNNPSCMLESSNRLDEEHRLIARYAARLA AESSSSQPPQQRSAPDISFTIDANKQQRQLIAE LENKNREILQEIQRLRLEHEQASQPTPEKAQQN PTLLAELRLLRQRKDELEQRMSALQESRRELMVQ LEGLMKLLKEEELKQGVSYVPYCRS*LTVEGPA DLRFSHCFCSNVCSCFSLEREKSHTNLLLFQCS A*IEIYKFSIFYNYHYYPHQKKNYDIF*KRERIV IYWKHFRSPEV*VSNQS*LFKLLIRPFS*QRDT TVTRDTLRFMSSQNPQHSEANLYTHSHCEYSVR FHFTENL*NLFL*KSGN*IPFHHTIIEPCSPWLT KMCSIL*EKDCTP*LTIHVPSFWLFPKAESLLL VDSNLFLKSNSQLFP*HQSLSAPGDERVITYFF FFLEIGAL*LYSLNWSCLNLWSGSRASRGSSKLK KKNKLN*IKLN*IEAK*KQL*FQVHVPRYV*QY IPLTSII*KFHIISMDQLEPQPVQFQRIFHFFC MLFSIIHYVCLCVTKNVWKMLDTFLPFIPMVCKK GKCKINL*CQTIKIMYYIILYFVKKITLLN*SQ ILTEDSP

Frame 2

LLCVEHKGKNEHSFLLKLKVTLEFVWKCVRSNT IVFSICSTSEEELRGMLVHLTTKPE*LKIVGKE EIPWQKEDSCLQR*GLKIWIASDSPPTEQHASL GLFRRNAICTWWTYGMS*KHCGKML*TTWTQTLN STCPA*RLCSPLFFTSSTNGCQPLTKSMWSSPS ASSLTSCLQRLIRKAMVKFQYLLSKWL*PHCVE GRSWTN*DIFSQ*FLTPVG*WFMDDMTNSFGKFS NYPRQFLKVLHLVTQNSQPDPVSPNRKKSR*MV SWTRLCQILPRSVWSGCLFCID*QMWKMSSIRL SVPTATVRV*WDFATDANSVTITSSVRTASGGDM PVVLIATSTK*KSTRHGNHLLRS*LMH*ASP*A VLPAVNLCTPCSQISLRSHSTWLTSCLPDL*PA *TTPCSPTLFPPQEVLLLPGALLPRTVK*SRTNC WLGLLQLF*RAKGYSTA*MWQTG*LMNMFSSGC MSTCSGTTPHACLRVQTGLMKNTG*LPGMRQGW QQSPLRLSHLSREVLLTSLSPSMRISSKGS*LLS *KTRTEKSYRRSRDFG*SMNKLLSPRQRRHSKT PPCWQNSGSSDSAKMSWNRECLLSRRAGES*WS SWRVS*SY*RKKN*SRE*VMSPTAGLN*QWRGLP TCGFLIAFALMYVHASVWKEKKVILICFFFNVV LELRYINLAFFITITTIHIKRRTMTSFRKGNEL SFIGNILDPQRYKFQTSLSFSSC*SDPSLNREIP QSLEIP*GSCHPKTHSTQKLTSTPTHTVSIQFG FILLKTCETSFYKNQAIKSLFITQLLSLVPHGS PKCAQFCERKTVLHN*LFTSHLFGSSPKQNPYCW LTVISF*KVTLSFFLSTRAFRLRETRGSLHTFF FFWK*GHCDFIA*TGAV*TCGQAQEPAGGAANS KKKTN*IKLN*IK*KQNKSSFNFKCMYHAMYDNI SHSLALFKSFTLFPWIN*NHNLSNFNVSFISSV CSFLLFIMCVCV*QRMFGKCWTHFYPSFPWSVK KESVKSICNVRQ*R*CITLFCIL*KKLLY*IKVK F*QKTVP

Sequence NM_001390

GATTGCTGTGTGTTGAGCACAAGGGGAAGAATGAACACAGCTTTTTATTGAAGTTAAAGGTTACTTTGGAGTTTGTTTGGAAATGTGTAAGGTCAAATAC TATAGTTTTCAGCATATGTAGTACTTCAGAGGAAGAATTAAGGGGCATGTTGGTGCATTTAACTACAAAACCAGGTGGCAGGTTGCTGCTCTCTCCTTCA GAACCCCGCTCTGAGGAAAGCTAAGGAAGAGAACAGGACGTCTGAGTGTGTGACTGAGAATGATTGAAGATAGTGGGAAAAGAGGAAATACCATGGCAGA AAGAAGACAGCTGTTTGCAGAGATGAGGGCTCAAGATCTGGATCGCATCCGACTCTCCACCTACAGAACAGCATGCAAGCTTAGGTTTGTTCAGAAGAAA TGCAATTTGCACCTGGTGGACATATGGAATGTCATAGAAGCATTGCGGGAAAATGCTCTGAACAACCTGGACCCAAACACTGAACTCAACGTGTCCCGCT TAGAGGCTGTGCTCTCCACTATTTTTTACCAGCTCAACAAACGGATGCCAACCACTCACCAAATCCATGTGGAGCAGTCCATCAGCCTCCTCCTTAACTT CCTGCTTGCAGCGTTTGATCCGGAAGGCCATGGTAAAATTTCAGTATTTGCTGTCAAAATGGCTTTAGCCACATTGTGTGGAGGGAAGATCATGGACAAA TTAAGATATATTTTCTCAATGATTTCTGACTCCAGTGGGGTGATGGTTTATGGACGATATGACCAATTCCTTCGGGAAGTTCTCAAACTACCCACGGCAG TTTTTGAAGGTCCTTCATTTGGTTACACAGAACAGTCAGCCAGATCCTGTTTCTCCCAACAGAAAAAAGTCACGTTAAATGGTTTCTTGGACACGCTTAT GTCAGATCCTCCCCCGCAGTGTCTGGTCTGGTTGCCTCTTCTGCATCGACTAGCAAATGTGGAAAATGTCTTCCATCCGGTTGAGTGTTCCTACTGCCAC AGTGAGAGTATGATGGGATTTCGCTACCGATGCCAACAGTGTCACAATTACCAGCTCTGTCAGGACTGCTTCTGGAGGGGACATGCCGGTGGTTCTCATA GCAACCAGCACCAAATGAAAGAGTACACGTCATGGAAATCACCTGCTAAGAAGCTGACTAATGCATTAAGCAAGTCCCTGAGCTGTGCTTCCAGCCGTGA ACCTTTGCACCCCATGTTCCCAGATCAGCCTGAGAAGCCACTCAACTTGGCTCACATCGTTGATACTTGGCCTCCCAGACCTGTAACCAGCATGAACGAC ACCCTGTTCTCCCACTCTGTTCCCTCCTCAGGAAGTCCTTTTATTACCAGGAGCTCTCCTCCCAAGGACAGTGAAGTAGAGCAGAACAAACTGCTGGCTA GGGCTGCTCCAGCTTTTCTGAAGGGCAAAGGGATACAGTACAGCCTGAATGTGGCAGACAGGCTAGCTGATGAACATGTTCTCATCGGGTTGTATGTCAA CATGCTCCGGAACAACCCCTCATGCATGCTTGAGAGTTCAAACCGGCTTGATGAAGAACACAGGCTAATTGCCAGGTATGCGGCAAGGCTGGCAGCAGAG TCCTCTTCGTCTCAGCCACCTCAGCAGAGAAGTGCTCCTGACATCTCTTTCACCATCGATGCGAATAAGCAGCAAAGGCAGCTGATTGCTGAGCTAGAAA ACAAGAACAGAGAAATCTTACAGGAGATCCAGAGACTTCGGCTAGAGCATGAACAAGCTTCTCAGCCCACGCCAGAGAAGGCACAGCAAAACCCCACCCT GCTGGCAGAACTCCGGCTCCTCAGACAGCGCAAAGATGAGCTGGAACAGAGAATGTCTGCTCTCCAGGAGAGCCGGAGAGAGCTAATGGTCCAGTTGGAG GGTCTCATGAAGCTACTAAAGACTCAGGGGGCAGGCTCTCCCCGCTCCTCCCCCAGCCACACCATCAGCAGGCCAATTCCCATGCCCATCCGGTCAGCGT CAGCCTGCTCCACCCCGACGCACACGCCGCAGGACTCCCTCACAGGAGTAGGGGGAGATGTACAAGAGGCATTTGCACAAAGTTCAAGAAGAAACTTAAG GAATGACTTGCTAGTGGCTGCAGATTCCATCACTAACACTATGTCCTCTCTTGTGAAAGAGCTGAATTCTGAGGTTGGGAGTGAAACAGAGAGTAATGTG GATTCTGAATTTGCACGGACTCAGTTTGAGGATCTTGTTCCCTCACCAACCTCTGAAAAGGCTTTTCTAGCGCAAATCCATGCCCGAAAACCTGGGTACA TTCACAGTGGAGCTACCACAAGTACCATGCGTGGCGACATGGTTACGGAGGATGCAGATCCCTATGTGCAGCCTGAAGATGAAAACTATGAAAATGACTC TGTCCGGCAGCTGGAGAATGAGCTCCAGATGGAGGAATACCTGAAACAGAAGCTGCAAGATGAAGCTTATCAGGTCAGCTTGCAAGGTTGAATGCAATAT CCTTTTATCACACTCCTCTCAAGCAAGCTATAGTCAGACAGATGATGAAAGTAACATGAAAACTGGTGATGATGGAGAGCCCTGTGGCCACACAGAGGAG GAAGACAGCAGCCTGGCAGCAGCCTCACCGAAGAGAGGAACCACCACACCCAGCAGCTCCTGACAGACCCCCACCCCTAAAGATGTGTCCTGATGACTAT AGTGCAGCTAACTTTTTGTTCTCAGATTTGTAGTGCATAGGTGTGTGTTTCAAGAAGGAAAAAAAAAGACTTCTGTTCAAAGTTAACTTATCAGCTACAT CCTCTGTAACGTGGTTCATCCCTGGTTAAAAAGCAAACAAACACAGGCTGAAAACCCATGCTGCTGTTATACACAATGGCAGTATTAACAAGCATTTTAA ACCTTTGCACATGATATTGAACCTGTTCAGTTTACAATGACAATATTAATACTGTTTATAGCTAGAAGTTTGATTTCTGAATTCTTTGAGATTTTAGCAA AACAGTTTATTATACACTGTACATTTTTTTCACAGCAATTGGAAAAAAACAACCACTTGCAATCATTCAATAACCCTGAAGAATTTGGTTCCTGAGTGTA CAAACTCAGAGCCCGGAAGCCAAGAAGGGTCCTTGGCCTGCACGGTCTGTAGTTGACTCCAAGTCTCTGTGAGCAGTGACTTGAACCAAACACACCAGGA ATAATCCATTCTTTGGGGCCTCTTTCCAACTCGAGGTTGTTTTCTTTCAAGATACTCTAATCAGCCATAGAATTTAGTGTAAATATTTTTTTTTCCAAAT AGATATCATATTCAAAAAAGGCAGCATTCAAATTATATAGAATCTAGTTTTTAAAATCAGCACAGATCTTCTTAAAAACTGTGAACTATGTTTTGAAATA CTCGTTACTAAAGCTGTTTATAAACCACAGGTGCCATAAGATCCCCAAACGGACTAAAGTTATCTCTGCTCTTCCATGGTCTTGTTCCTCTCGTTTTGGC TTTAGGAAGCATGTCTTTAACAGCACCGCTCGTTCACAAGTTCCCCCATCAAGTTGTTTGGAGGCCTTCAGCTTTAAATGTACAGGCTTAAAGTGCGCTT GCAAACGTTTGCTCTCCTTTTTTTCTGAATGTTGATTGCCTTAGCTGGCCACCTGGTGTTCTGCATGTAGCCTTCTGTGGTCATGTGAAAGGAGACAGGC TCTTCTAAGTTGAGTTGGGATTTTTGCACTCAGTGAAAAGCTGAAGTGCAAAAGAGCTATCAAAGACAAGAGGATAAAAGACTGGGATAGTCTTTTCCAA GGACCCTCTTTAGAGGGCCCTAAAGACCTCCTTTGGGAATTCTGGGGAAAAAGAAAAAGTAATCTTCTACTTGCTTCAAGATTTGATTTTTTTAAAAAAG CCTGCGACCTATTCAATACATTATGCTTAAATTAGCAGTTTCTCTGGAATTCCTGTCTCTCCTTTAAAAGAAAGGAGAGAACATTTTAGAACAATAGTTC TCAAAGTGTGTTCCCCGGACAAGCAGCATCTGCAACACTTAGGAAGGTCTTCGAAATACTAATTTGTAAGCCCCACCTCAGGCCTACTGAATCAGAAGCT CTGGGGGTTGGGTCCAGAAGTCTGTTTTAGTCAACCCTCTAGGTGATTCTGATGCTCGCTAAAGGTTGAGAACTACTGCTTTAGAATGAAGTCGTATAAT AAAGTCTCTGAAAAGGCCTTATTCAGAATAAGCAAGAAAGGTTCTGTGATTCACTTTTGCTTCTGGGGCTGGCAAAAACCTTCTCTGAACCCACACACCA AGTTCGTAGTTGGTAGGTGCCCAGCCAAGTCCTGACATCTTCATGCCCCCTCTGCAGAGGGCGGCTGTACGATGTTCACATGTCTGCGTTTGGTCAGACA TCATCTCCTTGGCTGCCCTTTGAAACCAAATCACTTGCCTTGGGGATAAAGTGCTCAATTGGCATTAGTGAGAAGCCCATCCTATCCCTTGACATACTTA ATCATATATCTCTCCAGAGAACTCACCTGACAAATGTCTCTGAGCACAGGCTGACACCAAAGTGGCACAACTGCACAGTTCTCAGATTTCTTTGCACAGA TTGATTTTTATTGCGGGTTTTGTTGGGGTGTCTTAATGTTCATCTCTTTTCCACTGCCCATCCTCTGTGAACCCATACCTCTCTAGATGGAGCAGGTGGC CACTGGTGCCTCATACTCAGTATTGAAAACCACTACATCCCAGCTACCTATAATGCTGTCAGCTCAAAATCATAGCCAGGTAGTTCTTGAACTCAGAACT TAAATCCTGCACGTGGCACTCCACCACTGACTGGACCGAGCTGGCATATGTTGTTTCTTTGTGTTTCTACATCAAAATGTTCGTCTAAGATTTGAACTGT TCTGCTGATAACCTTCCCCGTTGTCATAGCTATTTCATTGCCAACCAACTCCATCACATGGTTGTTGATATCGTCATATAAAGCCATTGCAAGGACTCTG GAAACTGCCGCCAATGACCAATTTCTGACTAACCAGCCACCTTTTCTCTCTCTTAGCTCCACGTCAGCACTGAGACCAGACTCGAGCACCCCTGTCCTGT AAGCGAGACAAAATGGCGTGTGTTATTTTGGGGTTTTGTGTTTTTTGGTGGGTTTCTTTCCTTGGCTCTCCAGATTTACTTTTGGGGCCTGTTCTAAGTG CAAACCCAGCAAGTTTCACTTGTCCTGTCCATTAGATACAACTACATCTTGCGGGGGTTGTTTCTTTCTTGTTCCACAATGAATTGCACATCCATCTCCA TCAGAGCTGATAGCCTGTTAATAAGCACTGGTCTAACACAGCCAACCCTCCTCCACAGCGCCATATTAATGGAGGAGGGGAGGAAGGTGAAATCTACTGC ATGGGATTCAGGAAACAGTTGTGGTTGGTCAGGACGGAAGTTGGGGTAAGTTTGGTTGGTCAGAGGGAGTTGTGCTGGAGATTGTGAAAAATGGGTTCTT GAATGATCTACTATAAGGCAGGGAAGGTTCATTTGTAAGTAGTAATGTGAACTGAATTGCATTAAGAGTGTGTGGCCTTTGTTGTGATATACTATGTATT TTCTTATATGCATGAGCCAAACTGTTGCATCATAATTTAGCACTGATGTCTGCTTTTATTTTGATCATCTTTGTCCACCCTTATTAGTTCTTGGCTGTTA ACCGTAGATAGATCTTGTAAATCCAGCAACCTTTGGTTGCTGCATTCCCCTTGGTTCGATTCCACGCAAGGAGCCACAAGTGAGAACTCCACTGTCCTTA GAAGAAAGGGCATTTTTACTTTTGAACCAAAAAGAGAAAAAAAAATCAGAAGTGTTGCATCTTGAGGCGAATTAACTGTAAGACATTTTTAATTATGACT ACTGCAATTTGACACCATTTGAAATAATCAATTCAGAGACACTAAAGATTTCACAATATTCATTGGTATTGTAAAAAAAAAATACTATTGTATGGATTTT TGTATTGCTGTTAAGTATTGTTTTGTGTGTGTGTGTGTGTGTGTGTGTTGGAACCTCCTGGGGACATGTTATATTTTGAAGTGATTAAACTATTTAATTG TGTGTCTATATTTTGGAGTGGAATAATTTCTTCATTAAAAAATGTTTTTAAAAACACTA

refseq_DTNA.F3 (forward primer)
refseq_DTNA.R3 (reverse primer)
Single exon skipping

Frame 0

DCCVLSTRGRMNTAFY*S*RLLWSLFGNV*GQI L*FSAYVVLQRKN*GACWCI*LQNQVAGCCSLLQ NPALRKAKEENRTSECVTEND*R*WEKRKYHGR KKTAVCRDEGSRSGSHPTLHLQNSMQA*VCSEE MQFAPGGHMECHRSIAGKCSEQPGPKH*TQRVPL RGCALHYFLPAQQTDANHSPNPCGAVHQPPP*L PACSV*SGRPW*NFSICCQNGFSHIVWREDHGQ IKIYFLNDF*LQWGDGLWTI*PIPSGSSQTTHGS F*RSFIWLHRTVSQILFLPTEKSHVKWFLGHAY VRSSPAVSGLVASSASTSKCGKCLPSG*VFLLP Q*EYDGISLPMPTVSQLPALSGLLLEGTCRWFS* QPAPNERVHVMEITC*EAD*CIKQVPELCFQP* TFAPHVPRSA*EATQLGSHR*YLASQTCNQHER HPVLPLCSLLRKSFYYQELSSQGQ*SRAEQTAG* GCSSFSEGQRDTVQPECGRQAS**TCSHRVVCQ HAPEQPLMHA*EFKPA**RTQANCQVCGKAGSR VLFVSATSAEKCS*HLFHHRCE*AAKAADC*ARK QEQRNLTGDPETSARA*TSFSAHAREGTAKPHP AGRTPAPQTAQR*AGTENVCSPGEPERANGPVG GSHEATKDSGGRLSPLLPQPHHQQANSHAHPVSV SLLHPDAHAAGLPHRSRGRCTRGICTKFKKKLK E*LASGCRFHH*HYVLSCERAEF*GWE*NRE*C GF*ICTDSV*GSCSLTNL*KGFSSANPCPKTWVH SQWSYHKYHAWRHGYGGCRSLCAA*R*KL*K*L CPAAGE*APDGGIPETEAAR*SLSGQLARLNAI SFYHTPLKQAIVRQMMKVT*KLVMMESPVATQRR KTAAWQQPHRREEPPHPAAPDRPPPLKMCPDDY SAANFLFSDL*CIGVCFKKEKKRLLFKVNLSAT SSVTWFIPG*KANKHRLKTHAAVIHNGSINKHFK PLHMILNLFSLQ*QY*YCL*LEV*FLNSLRF*Q NSLLYTVHFFHSNWKKTTTCNHSITLKNLVPEC TNSEPGSQEGSLACTVCS*LQVSVSSDLNQTHQE *SILWGLFPTRGCFLSRYSNQP*NLV*IFFFPN RYHIQKRQHSNYIESSF*NQHRSS*KL*TMF*N TRY*SCL*TTGAIRSPNGLKLSLLFHGLVPLVLA LGSMSLTAPLVHKFPHQVVWRPSALNVQA*SAL ANVCSPFFLNVDCLSWPPGVLHVAFCGHVKGDR LF*VELGFLHSVKS*SAKELSKTRG*KTGIVFSK DPL*RALKTSFGNSGEKEKVIFYLLQDLIFLKK PATYSIHYA*ISSFSGIPVSPLKERREHFRTIV LKVCSPDKQHLQHLGRSSKY*FVSPTSGLLNQKL WGLGPEVCFSQPSR*F*CSLKVENYCFRMKSYN KVSEKALFRISKKGSVIHFCFWGWQKPSLNPHT KFVVGRCPAKS*HLHAPSAEGGCTMFTCLRLVRH HLLGCPLKPNHLPWG*SAQLALVRSPSYPLTYL IIYLSRELT*QMSLSTG*HQSGTTAQFSDFFAQ IDFYCGFCWGVLMFISFPLPILCEPIPL*MEQVA TGASYSVLKTTTSQLPIMLSAQNHSQVVLELRT *ILHVALHH*LDRAGICCFFVFLHQNVRLRFEL FC**PSPLS*LFHCQPTPSHGC*YRHIKPLQGLW KLPPMTNF*LTSHLFSLLAPRQH*DQTRAPLSC KRDKMACVILGFCVFWWVSFLGSPDLLLGPVLS ANPASFTCPVH*IQLHLAGVVSFLFHNELHIHLH QS**PVNKHWSNTANPPPQRHINGGGEEGEIYC MGFRKQLWLVRTEVGVSLVGQRELCWRL*KMGS *MIYYKAGKVHL*VVM*TELH*ECVAFVVIYYVF SYMHEPNCCIII*H*CLLLF*SSLSTLISSWLL TVDRSCKSSNLWLLHSPWFDSTQGATSENSTVL RRKGIFTFEPKREKKIRSVAS*GELTVRHF*L*L LQFDTI*NNQFRDTKDFTIFIGIVKKKYYCMDF CIAVKYCFVCVCVCVCWNLLGTCYILK*LNYLI VCLYFGVE*FLH*KMFLKTL

Frame 1

IAVC*AQGEE*TQLFIEVKGYFGVCLEMCKVKY YSFQHM*YFRGRIKGHVGAFNYKTRWQVAALSF RTPL*GKLRKRTGRLSV*LRMIEDSGKRGNTMAE RRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKK CNLHLVDIWNVIEALRENALNNLDPNTELNVSR LEAVLSTIFYQLNKRMPTTHQIHVEQSISLLLNF LLAAFDPEGHGKISVFAVKMALATLCGGKIMDK LRYIFSMISDSSGVMVYGRYDQFLREVLKLPTA VFEGPSFGYTEQSARSCFSQQKKVTLNGFLDTLM SDPPPQCLVWLPLLHRLANVENVFHPVECSYCH SESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSH SNQHQMKEYTSWKSPAKKLTNALSKSLSCASSRE PLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMND TLFSHSVPSSGSPFITRSSPPKDSEVEQNKLLA RAAPAFLKGKGIQYSLNVADRLADEHVLIGLYVN MLRNNPSCMLESSNRLDEEHRLIARYAARLAAE SSSSQPPQQRSAPDISFTIDANKQQRQLIAELE NKNREILQEIQRLRLEHEQASQPTPEKAQQNPTL LAELRLLRQRKDELEQRMSALQESRRELMVQLE GLMKLLKTQGAGSPRSSPSHTISRPIPMPIRSA SACSTPTHTPQDSLTGVGGDVQEAFAQSSRRNLR NDLLVAADSITNTMSSLVKELNSEVGSETESNV DSEFARTQFEDLVPSPTSEKAFLAQIHARKPGY IHSGATTSTMRGDMVTEDADPYVQPEDENYENDS VRQLENELQMEEYLKQKLQDEAYQVSLQG*MQY PFITLLSSKL*SDR**K*HENW**WRALWPHRG GRQQPGSSLTEERNHHTQQLLTDPHP*RCVLMTI VQLTFCSQICSA*VCVSRRKKKDFCSKLTYQLH PL*RGSSLVKKQTNTG*KPMLLLYTMAVLTSIL NLCT*Y*TCSVYNDNINTVYS*KFDF*IL*DFSK TVYYTLYIFFTAIGKKQPLAIIQ*P*RIWFLSV QTQSPEAKKGPWPARSVVDSKSL*AVT*TKHTR NNPFFGASFQLEVVFFQDTLISHRI*CKYFFFQI DIIFKKGSIQII*NLVFKISTDLLKNCELCFEI LVTKAVYKPQVP*DPQTD*SYLCSSMVLFLSFW L*EACL*QHRSFTSSPIKLFGGLQL*MYRLKVRL QTFALLFF*MLIALAGHLVFCM*PSVVM*KETG SSKLSWDFCTQ*KAEVQKSYQRQEDKRLG*SFP RTLFRGP*RPPLGILGKKKK*SSTCFKI*FF*KS LRPIQYIMLKLAVSLEFLSLL*KKGENILEQ*F SKCVPRTSSICNT*EGLRNTNL*APPQAY*IRS SGGWVQKSVLVNPLGDSDAR*RLRTTALE*SRII KSLKRPYSE*ARKVL*FTFASGAGKNLL*THTP SS*LVGAQPSPDIFMPPLQRAAVRCSHVCVWSD IISLAAL*NQITCLGDKVLNWH**EAHPIP*HT* SYISPENSPDKCL*AQADTKVAQLHSSQISLHR LIFIAGFVGVS*CSSLFHCPSSVNPYLSRWSRW PLVPHTQY*KPLHPSYL*CCQLKIIAR*FLNSEL KSCTWHSTTDWTELAYVVSLCFYIKMFV*DLNC SADNLPRCHSYFIANQLHHMVVDIVI*SHCKDS GNCRQ*PISD*PATFSLS*LHVSTETRLEHPCPV SETKWRVLFWGFVFFGGFLSLALQIYFWGLF*V QTQQVSLVLSIRYNYILRGLFLSCSTMNCTSIS IRADSLLISTGLTQPTLLHSAILMEEGRKVKSTA WDSGNSCGWSGRKLG*VWLVRGSCAGDCEKWVL E*STIRQGRFICK**CELNCIKSVWPLL*YTMY FLICMSQTVAS*FSTDVCFYFDHLCPPLLVLGC* P*IDLVNPATFGCCIPLGSIPRKEPQVRTPLSL EERAFLLLNQKEKKKSEVLHLEAN*L*DIFNYD YCNLTPFEIINSETLKISQYSLVL*KKNTIVWIF VLLLSIVLCVCVCVCVGTSWGHVIF*SD*TI*L CVYILEWNNFFIKKCF*KH

Frame 2

LLCVEHKGKNEHSFLLKLKVTLEFVWKCVRSNT IVFSICSTSEEELRGMLVHLTTKPGGRLLLSPS EPRSEES*GREQDV*VCD*E*LKIVGKEEIPWQ KEDSCLQR*GLKIWIASDSPPTEQHASLGLFRRN AICTWWTYGMS*KHCGKML*TTWTQTLNSTCPA *RLCSPLFFTSSTNGCQPLTKSMWSSPSASSLT SCLQRLIRKAMVKFQYLLSKWL*PHCVEGRSWTN *DIFSQ*FLTPVG*WFMDDMTNSFGKFSNYPRQ FLKVLHLVTQNSQPDPVSPNRKKSR*MVSWTRL CQILPRSVWSGCLFCID*QMWKMSSIRLSVPTAT VRV*WDFATDANSVTITSSVRTASGGDMPVVLI ATSTK*KSTRHGNHLLRS*LMH*ASP*AVLPAV NLCTPCSQISLRSHSTWLTSLILGLPDL*PA*TT PCSPTLFPPQEVLLLPGALLPRTVK*SRTNCWL GLLQLF*RAKGYSTA*MWQTG*LMNMFSSGCMS TCSGTTPHACLRVQTGLMKNTG*LPGMRQGWQQS PLRLSHLSREVLLTSLSPSMRISSKGS*LLS*K TRTEKSYRRSRDFG*SMNKLLSPRQRRHSKTPP CWQNSGSSDSAKMSWNRECLLSRRAGES*WSSWR VS*SY*RLRGQALPAPPPATPSAGQFPCPSGQR QPAPPRRTRRRTPSQE*GEMYKRHLHKVQEET* GMTC*WLQIPSLTLCPLL*KS*ILRLGVKQRVMW ILNLHGLSLRILFPHQPLKRLF*RKSMPENLGT FTVELPQVPCVATWLRRMQIPMCSLKMKTMKMT LSGSWRMSSRWRNT*NRSCKMKLIRSACKVECNI LLSHSSQASYSQTDDESNMKTGDDGEPCGHTEE EDSSLAAASPKRGTTTPSSS*QTPTPKDVS**L *CS*LFVLRFVVHRCVFQEGKKKTSVQS*LISYI LCNVVHPWLKSKQTQAENPCCCYTQWQY*QAF* TFAHDIEPVQFTMTILILFIARSLISEFFEILA KQFIIHCTFFSQQLEKNNHLQSFNNPEEFGS*VY KLRARKPRRVLGLHGL*LTPSLCEQ*LEPNTPG IIHSLGPLSNSRLFSFKIL*SAIEFSVNIFFSK *ISYSKKAAFKLYRI*FLKSAQIFLKTVNYVLKY SLLKLFINHRCHKIPKRTKVISALPWSCSSRFG FRKHVFNSTARSQVPPSSCLEAFSFKCTGLKCA CKRLLSFFSEC*LP*LATWCSACSLLWSCERRQA LLS*VGIFALSEKLKCKRAIKDKRIKDWDSLFQ GPSLEGPKDLLWEFWGKRKSNLLLASRFDFFKK ACDLFNTLCLN*QFLWNSCLSFKRKERTF*NNSS QSVFPGQAASATLRKVFEILICKPHLRPTESEA LGVGSRSLF*STL*VILMLAKG*ELLL*NEVV* *SL*KGLIQNKQERFCDSLLLLGLAKTFSEPTHQ VRSW*VPSQVLTSSCPLCRGRLYDVHMSAFGQT SSPWLPFETKSLALGIKCSIGISEKPILSLDIL NHISLQRTHLTNVSEHRLTPKWHNCTVLRFLCTD *FLLRVLLGCLNVHLFSTAHPL*THTSLDGAGG HWCLILSIENHYIPATYNAVSSKS*PGSS*TQN LNPARGTPPLTGPSWHMLFLCVSTSKCSSKI*TV LLITFPVVIAISLPTNSITWLLISSYKAIARTL ETAANDQFLTNQPPFLSLSSTSALRPDSSTPVL *ARQNGVCYFGVLCFLVGFFPWLSRFTFGACSKC KPSKFHLSCPLDTTTSCGGCFFLVPQ*IAHPSP SELIAC**ALV*HSQPSSTAPY*WRRGGR*NLL HGIQETVVVGQDGSWGKFGWSEGVVLEIVKNGFL NDLL*GREGSFVSSNVN*IALRVCGLCCDILCI FLYA*AKLLHHNLALMSAFILIIFVHPY*FLAV NRR*IL*IQQPLVAAFPLVRFHARSHK*ELHCP* KKGHFYF*TKKRKKNQKCCILRRINCKTFLIMT TAI*HHLK*SIQRH*RFHNIHWYCKKKILLYGF LYCC*VLFCVCVCVCVLEPPGDMLYFEVIKLFNC VSIFWSGIISSLKNVFKNT

Sequence NM_032978

Frame 0

Frame 1

Frame 2

Sequence NM_001390

Frame 0

Frame 1

Frame 2

Sequence NM_001391

Frame 0

Frame 1

Frame 2