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Sequences

Sequence NM_012161

GCGGGCGCATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGGCCGCGGCTGCTGAGGCGGAGGCTGAGGCAGTG GCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGAAGCAGCTGGTGGGGCTCTACTGCGACAAGCTTTCTAAAACCA ATTTTTCCAACAACAACGATTTCCGTGCTCTTCTGCAGTCTTTGTATGCTACTTTCAAGGAGTTCAAAATGCATGAGCAGATTGAAAATGAATACATTAT TGGTTTGCTTCAACAACGCAGCCAGACCATTTATAATGTACATTCTGACAATAAACTCTCCGAGATGCTTAGCCTCTTTGAAAAGGGACTGAAGAATGTT AAGAATGAATATGAACAGTTAAATTATGCAAAACAACTGAAAGAGAGATTGGAGGCTTTTACAAGAGATTTTCTTCCTCACATGAAAGAGGAAGAGGAGG TTTTTCAGCCCATGTTAATGGAATATTTTACCTATGAAGAGCTTAAGGATATTAAAAAGAAAGTGATTGCACAACACTGCTCTCAGAAGGATACTGCAGA ACTCCTTAGAGGTCTTAGCCTATGGAATCATGCTGAAGAGCGACAGAAGTTTTTTAAATATTCCGTGGATGAAAAGTCAGATAAAGAAGCAGAAGTGTCA GAACACTCCACAGGTATAACCCATCTTCCTCCTGAGGTAATGCTGTCAATTTTCAGCTATCTTAATCCTCAAGAGTTATGTCGATGCAGTCAAGTAAGCA TGAAATGGTCTCAGCTGACAAAAACGGGATCGCTTTGGAAACATCTTTACCCTGTTCATTGGGCCAGAGGTGACTGGTATAGTGGTCCCGCAACTGAACT TGATACTGAACCTGATGATGAATGGGTGAAAAATAGGAAAGATGAAAGTCGTGCTTTTCATGAGTGGGATGAAGATGCTGACATTGATGAATCTGAAGAG TCTGCGGAGGAATCAATTGCTATCAGCATTGCACAAATGGAAAAACGTTTACTCCATGGCTTAATTCATAACGTTCTACCATATGTTGGTACTTCTGTAA AAACCTTAGTATTAGCATACAGCTCTGCAGTTTCCAGCAAAATGGTTAGGCAGATTTTAGAGCTTTGTCCTAACCTGGAGCATCTGGATCTTACCCAGAC TGACATTTCAGATTCTGCATTTGACAGTTGGTCTTGGCTTGGTTGCTGCCAGAGTCTTCGGCATCTTGATCTGTCTGGTTGTGAGAAAATCACAGATGTG GCCCTAGAGAAGATTTCCAGAGCTCTTGGAATTCTGACATCTCATCAAAGTGGCTTTTTGAAAACATCTACAAGCAAAATTACTTCAACTGCGTGGAAAA ATAAAGACATTACCATGCAGTCCACCAAGCAGTATGCCTGTTTGCACGATTTAACTAACAAGGGCATTGGAGAAGAAATAGATAATGAACACCCCTGGAC TAAGCCTGTTTCTTCTGAGAATTTCACTTCTCCTTATGTGTGGATGTTAGATGCTGAAGATTTGGCTGATATTGAAGATACTGTGGAATGGAGACATAGA AATGTTGAAAGTCTTTGTGTAATGGAAACAGCATCCAACTTTAGTTGTTCCACCTCTGGTTGTTTTAGTAAGGACATTGTTGGACTAAGGACTAGTGTCT GTTGGCAGCAGCATTGTGCTTCTCCAGCCTTTGCGTATTGTGGTCACTCATTTTGTTGTACAGGAACAGCTTTAAGAACTATGTCATCACTCCCAGAATC TTCTGCAATGTGTAGAAAAGCAGCAAGGACTAGATTGCCTAGGGGAAAAGACTTAATTTACTTTGGGAGTGAAAAATCTGATCAAGAGACTGGACGTGTA CTTCTGTTTCTCAGTTTATCTGGATGTTATCAGATCACAGACCATGGTCTCAGGGTTTTGACTCTGGGAGGAGGGCTGCCTTATTTGGAGCACCTTAATC TCTCTGGTTGTCTTACTATAACTGGTGCAGGCCTGCAGGATTTGGTTTCAGCATGTCCTTCTCTGAATGATGAATACTTTTACTACTGTGACAACATTAA CGGTCCTCATGCTGATACCGCCAGTGGATGCCAGAATTTGCAGTGTGGTTTTCGAGCCTGCTGCCGCTCTGGCGAATGACCCTTGACTTCTGATCTTTGT CTACTTCATTTAGCTGAGCAGGCTTTCTTTCATGCACTTTACTCATAGCACATTTCTTGTGTTAACCATCCCTTTTTGAGCGTGACTTGTTTTGGCCCCA TTTCTTACAACTTCAGAAATCTTAATTTACCAGTGAATTGTAATGTTGTTTCTCTTGCAAATTATACTTTTGGTTTAGAAAGGGATTAGGTCTTTTCAAA AGGGTGAGAACAGTCTTACATTTTTCTTTTAAATGAAATGCTTTAAAGAATGTTGGTAATGCCATGTCATTTAAAGTATTTCATAGATAATTTTGAGTTT TAAAGTCCATGGAGGTGATTGGTTCTCTTTACACATTAACACTGTACCAAGCTTTGCAGATCTTTTCCGACACACATGTCTGAAGACTTATTTTCAAAGA CAGCACATTTTTGGAAACTAATCTCTTTTCCGTAATATTTCCTTTATTTCAATGATTCTCAGAAGGCCAATTCAAACAAACCCACATTTAAGGTTCTTTA GGATTATAGAATAAATTGGCTTCTGAGTGTTAGCTCAGTGAGCTAGGAAAGCACCAATCGATATTTGTTTCCTTTAGGGATACTTTGTTCTCACCACTGT CCCTATGTCATCAAATTTGGGAGAGATTTTTTAAAATACCACAATCATTTGAAGAAATGTATAAATAAAATCTACTTTGAGGACTTTACCAAGTAATACT GTTGTGTTGTGATTTTTATTATAAATCTCAATCCAGGTTTACTTTAGTATAGAATAGGACTACATACTTTGTCTTTGGACCTCCCATGAACTTATTACCC TGACAAATAGTTTTAGACAGATACTGAATTTTATTGAGCTGAATTTTCTTTTTGAAATGAGTTATTCAGTAGTCAAAATTTGAATCCGTAAGTATATCTA CTTTGCTTTGTTAAAACATCATGAGAGTGGAGGCCTGCCACCCAGAAAGGCACATACTAGTGCCTTTTAGTACAATTTTATGTCATGTAGAAGAAAATGG CAATGTTCCTCCTATTGATACAGATACAGGCATATGTCATCTTATTGCGTTTTGCTTTATTGCACTTTGCAAATAATGCATTTTTTACAAATGGAAGGTT TATGGCAACTCTGCGTTGAGCCAGTCTATTGGTGCCATGTTTCCAATAAAACTTCTCCTTTCATGTCTCGT

refseq_FBXL5.F1 (forward primer)
refseq_FBXL5.R1 (reverse primer)
Single exon skipping

Frame 0

AGACARGRAASAPRRGCLWRGGGRGC*GGG*GS GDGALS*RSGRLHRPTLADEAAGGALLRQAF*NQ FFQQQRFPCSSAVFVCYFQGVQNA*AD*K*IHY WFASTTQPDHL*CTF*Q*TLRDA*PL*KGTEEC *E*I*TVKLCKTTEREIGGFYKRFSSSHERGRGG FSAHVNGIFYL*RA*GY*KESDCTTLLSEGYCR TP*RS*PMESC*RATEVF*IFRG*KVR*RSRSV RTLHRYNPSSS*GNAVNFQLS*SSRVMSMQSSKH EMVSADKNGIALETSLPCSLGQR*LV*WSRN*T *Y*T***MGEK*ER*KSCFS*VG*RC*H**I*R VCGGINCYQHCTNGKTFTPWLNS*RSTICWYFCK NLSISIQLCSFQQNG*ADFRALS*PGASGSYPD *HFRFCI*QLVLAWLLPESSAS*SVWL*ENHRC GPREDFQSSWNSDISSKWLFENIYKQNYFNCVEK *RHYHAVHQAVCLFARFN*QGHWRRNR**TPLD *ACFF*EFHFSLCVDVRC*RFG*Y*RYCGMET* KC*KSLCNGNSIQL*LFHLWLF**GHCWTKD*CL LAAALCFSSLCVLWSLILLYRNSFKNYVITPRI FCNV*KSSKD*IA*GKRLNLLWE*KI*SRDWTC TSVSQFIWMLSDHRPWSQGFDSGRRAALFGAP*S LWLSYYNWCRPAGFGFSMSFSE**ILLLL*QH* RSSC*YRQWMPEFAVWFSSLLPLWRMTLDF*SL STSFS*AGFLSCTLLIAHFLC*PSLFERDLFWPH FLQLQKS*FTSEL*CCFSCKLYFWFRKGLGLFK RVRTVLHFSFK*NALKNVGNAMSFKVFHR*F*V LKSMEVIGSLYTLTLYQALQIFSDTHV*RLIFKD STFLETNLFSVIFPLFQ*FSEGQFKQTHI*GSL GL*NKLASEC*LSELGKHQSIFVSFRDTLFSPL SLCHQIWERFFKIPQSFEEMYK*NLL*GLYQVIL LCCDFYYKSQSRFTLV*NRTTYFVFGPPMNLLP *QIVLDRY*ILLS*IFFLK*VIQ*SKFESVSIS TLLC*NIMRVEACHPERHILVPFSTILCHVEENG NVPPIDTDTGICHLIAFCFIALCK*CIFYKWKV YGNSALSQSIGAMFPIKLLLSCL

Frame 1

RAHAQGGAPPLPRGEGVYGEAAAAAAEAEAEAV AMAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKT NFSNNNDFRALLQSLYATFKEFKMHEQIENEYII GLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNV KNEYEQLNYAKQLKERLEAFTRDFLPHMKEEEE VFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAE LLRGLSLWNHAEERQKFFKYSVDEKSDKEAEVS EHSTGITHLPPEVMLSIFSYLNPQELCRCSQVS MKWSQLTKTGSLWKHLYPVHWARGDWYSGPATEL DTEPDDEWVKNRKDESRAFHEWDEDADIDESEE SAEESIAISIAQMEKRLLHGLIHNVLPYVGTSV KTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQT DISDSAFDSWSWLGCCQSLRHLDLSGCEKITDV ALEKISRALGILTSHQSGFLKTSTSKITSTAWK NKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWT KPVSSENFTSPYVWMLDAEDLADIEDTVEWRHR NVESLCVMETASNFSCSTSGCFSKDIVGLRTSV CWQQHCASPAFAYCGHSFCCTGTALRTMSSLPES SAMCRKAARTRLPRGKDLIYFGSEKSDQETGRV LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLN LSGCLTITGAGLQDLVSACPSLNDEYFYYCDNIN GPHADTASGCQNLQCGFRACCRSGE*PLTSDLC LLHLAEQAFFHALYS*HISCVNHPFLSVTCFGP ISYNFRNLNLPVNCNVVSLANYTFGLERD*VFSK G*EQSYIFLLNEML*RMLVMPCHLKYFIDNFEF *SPWR*LVLFTH*HCTKLCRSFPTHMSEDLFSK TAHFWKLISFP*YFLYFNDSQKANSNKPTFKVL* DYRINWLLSVSSVS*ESTNRYLFPLGILCSHHC PYVIKFGRDFLKYHNHLKKCINKIYFEDFTK*Y CCVVIFIINLNPGLL*YRIGLHTLSLDLP*TYYP DK*F*TDTEFY*AEFSF*NELFSSQNLNP*VYL LCFVKTS*EWRPATQKGTY*CLLVQFYVM*KKM AMFLLLIQIQAYVILLRFALLHFANNAFFTNGRF MATLR*ASLLVPCFQ*NFSFHVS

Frame 2

GRMRKGARRLCPAARVSMERRRPRLLRRRLRQW RWRPFLKKWTSSPPHTGG*SSWWGSTATSFLKP IFPTTTISVLFCSLCMLLSRSSKCMSRLKMNTL LVCFNNAARPFIMYILTINSPRCLASLKRD*RML RMNMNS*IMQNN*KRDWRLLQEIFFLT*KRKRR FFSPC*WNILPMKSLRILKRK*LHNTALRRILQ NSLEVLAYGIMLKSDRSFLNIPWMKSQIKKQKCQ NTPQV*PIFLLR*CCQFSAILILKSYVDAVK*A *NGLS*QKRDRFGNIFTLFIGPEVTGIVVPQLN LILNLMMNG*KIGKMKVVLFMSGMKMLTLMNLKS LRRNQLLSALHKWKNVYSMA*FITFYHMLVLL* KP*Y*HTALQFPAKWLGRF*SFVLTWSIWILPR LTFQILHLTVGLGLVAARVFGILICLVVRKSQMW P*RRFPELLEF*HLIKVAF*KHLQAKLLQLRGK IKTLPCSPPSSMPVCTI*LTRALEKK*IMNTPG LSLFLLRISLLLMCGC*MLKIWLILKILWNGDIE MLKVFV*WKQHPTLVVPPLVVLVRTLLD*GLVS VGSSIVLLQPLRIVVTHFVVQEQL*ELCHHSQN LLQCVEKQQGLDCLGEKT*FTLGVKNLIKRLDVY FCFSVYLDVIRSQTMVSGF*LWEEGCLIWSTLI SLVVLL*LVQACRIWFQHVLL*MMNTFTTVTTL TVLMLIPPVDARICSVVFEPAAALANDP*LLIFV YFI*LSRLSFMHFTHSTFLVLTIPF*A*LVLAP FLTTSEILIYQ*IVMLFLLQIILLV*KGIRSFQ KGENSLTFFF*MKCFKECW*CHVI*SIS*IILSF KVHGGDWFSLHINTVPSFADLFRHTCLKTYFQR QHIFGN*SLFRNISFISMILRRPIQTNPHLRFF RIIE*IGF*VLAQ*ARKAPIDICFL*GYFVLTTV PMSSNLGEIF*NTTII*RNV*IKSTLRTLPSNT VVL*FLL*ISIQVYFSIE*DYILCLWTSHELIT LTNSFRQILNFIELNFLFEMSYSVVKI*IRKYIY FALLKHHESGGLPPRKAHTSAF*YNFMSCRRKW QCSSY*YRYRHMSSYCVLLYCTLQIMHFLQMEG LWQLCVEPVYWCHVSNKTSPFMSR

Sequence NM_033535

GCGGGCGCATGCGCAAGGGGGCGCGCCGCCTCTGCCCCGCGGCGAGGGTGTCTATGGAGAGGCGGCGGCCGCGGCTGCTGAGGCGGAGGCTGAGGCAGTG GCGATGGCGCCCTTTCCTGAAGAAGTGGACGTCTTCACCGCCCCACACTGGCGGATGAAGCAGCTGGTGGGGCTCTACTGCGACAAGCTTTCTAAAACCA ATTTTTCCAACAACAACGATTTCCGTGCTCTTCTGCAGTCTTTGTATGCTACTTTCAAGGAGTTCAAAATGCATGAGCAGATTGAAAATGAATACATTAT TGGTTTGCTTCAACAACGCAGCCAGACCATTTATAATGTACATTCTGACAATAAACTCTCCGAGATGCTTAGCCTCTTTGAAAAGGGACTGAAGAATGTT AAGCCTACTACTGTTGACTGGAAGCCTTACCAATAACATAAAACAATCGAATAACAATTATTTCATGTATTATATGTAAAATATATATACTGGATTCTTA CAGTAAGAATGAATATGAACAGTTAAATTATGCAAAACAACTGAAAGAGAGATTGGAGGCTTTTACAAGAGATTTTCTTCCTCACATGAAAGAGGAAGAG GAGGTTTTTCAGCCCATGTTAATGGAATATTTTACCTATGAAGAGCTTAAGGATATTAAAAAGAAAGTGATTGCACAACACTGCTCTCAGAAGGATACTG CAGAACTCCTTAGAGGTCTTAGCCTATGGAATCATGCTGAAGAGCGACAGAAGTTTTTTAAATATTCCGTGGATGAAAAGTCAGATAAAGAAGCAGAAGT GTCAGAACACTCCACAGGTATAACCCATCTTCCTCCTGAGGTAATGCTGTCAATTTTCAGCTATCTTAATCCTCAAGAGTTATGTCGATGCAGTCAAGTA AGCATGAAATGGTCTCAGCTGACAAAAACGGGATCGCTTTGGAAACATCTTTACCCTGTTCATTGGGCCAGAGGTGACTGGTATAGTGGTCCCGCAACTG AACTTGATACTGAACCTGATGATGAATGGGTGAAAAATAGGAAAGATGAAAGTCGTGCTTTTCATGAGTGGGATGAAGATGCTGACATTGATGAATCTGA AGAGTCTGCGGAGGAATCAATTGCTATCAGCATTGCACAAATGGAAAAACGTTTACTCCATGGCTTAATTCATAACGTTCTACCATATGTTGGTACTTCT GTAAAAACCTTAGTATTAGCATACAGCTCTGCAGTTTCCAGCAAAATGGTTAGGCAGATTTTAGAGCTTTGTCCTAACCTGGAGCATCTGGATCTTACCC AGACTGACATTTCAGATTCTGCATTTGACAGTTGGTCTTGGCTTGGTTGCTGCCAGAGTCTTCGGCATCTTGATCTGTCTGGTTGTGAGAAAATCACAGA TGTGGCCCTAGAGAAGATTTCCAGAGCTCTTGGAATTCTGACATCTCATCAAAGTGGCTTTTTGAAAACATCTACAAGCAAAATTACTTCAACTGCGTGG AAAAATAAAGACATTACCATGCAGTCCACCAAGCAGTATGCCTGTTTGCACGATTTAACTAACAAGGGCATTGGAGAAGAAATAGATAATGAACACCCCT GGACTAAGCCTGTTTCTTCTGAGAATTTCACTTCTCCTTATGTGTGGATGTTAGATGCTGAAGATTTGGCTGATATTGAAGATACTGTGGAATGGAGACA TAGAAATGTTGAAAGTCTTTGTGTAATGGAAACAGCATCCAACTTTAGTTGTTCCACCTCTGGTTGTTTTAGTAAGGACATTGTTGGACTAAGGACTAGT GTCTGTTGGCAGCAGCATTGTGCTTCTCCAGCCTTTGCGTATTGTGGTCACTCATTTTGTTGTACAGGAACAGCTTTAAGAACTATGTCATCACTCCCAG AATCTTCTGCAATGTGTAGAAAAGCAGCAAGGACTAGATTGCCTAGGGGAAAAGACTTAATTTACTTTGGGAGTGAAAAATCTGATCAAGAGACTGGACG TGTACTTCTGTTTCTCAGTTTATCTGGATGTTATCAGATCACAGACCATGGTCTCAGGGTTTTGACTCTGGGAGGAGGGCTGCCTTATTTGGAGCACCTT AATCTCTCTGGTTGTCTTACTATAACTGGTGCAGGCCTGCAGGATTTGGTTTCAGCATGTCCTTCTCTGAATGATGAATACTTTTACTACTGTGACAACA TTAACGGTCCTCATGCTGATACCGCCAGTGGATGCCAGAATTTGCAGTGTGGTTTTCGAGCCTGCTGCCGCTCTGGCGAATGACCCTTGACTTCTGATCT TTGTCTACTTCATTTAGCTGAGCAGGCTTTCTTTCATGCACTTTACTCATAGCACATTTCTTGTGTTAACCATCCCTTTTTGAGCGTGACTTGTTTTGGC CCCATTTCTTACAACTTCAGAAATCTTAATTTACCAGTGAATTGTAATGTTGTTTCTCTTGCAAATTATACTTTTGGTTTAGAAAGGGATTAGGTCTTTT CAAAAGGGTGAGAACAGTCTTACATTTTTCTTTTAAATGAAATGCTTTAAAGAATGTTGGTAATGCCATGTCATTTAAAGTATTTCATAGATAATTTTGA GTTTTAAAGTCCATGGAGGTGATTGGTTCTCTTTACACATTAACACTGTACCAAGCTTTGCAGATCTTTTCCGACACACATGTCTGAAGACTTATTTTCA AAGACAGCACATTTTTGGAAACTAATCTCTTTTCCGTAATATTTCCTTTATTTCAATGATTCTCAGAAGGCCAATTCAAACAAACCCACATTTAAGGTTC TTTAGGATTATAGAATAAATTGGCTTCTGAGTGTTAGCTCAGTGAGCTAGGAAAGCACCAATCGATATTTGTTTCCTTTAGGGATACTTTGTTCTCACCA CTGTCCCTATGTCATCAAATTTGGGAGAGATTTTTTAAAATACCACAATCATTTGAAGAAATGTATAAATAAAATCTACTTTGAGGACTTTACCAAGTAA TACTGTTGTGTTGTGATTTTTATTATAAATCTCAATCCAGGTTTACTTTAGTATAGAATAGGACTACATACTTTGTCTTTGGACCTCCCATGAACTTATT ACCCTGACAAATAGTTTTAGACAGATACTGAATTTTATTGAGCTGAATTTTCTTTTTGAAATGAGTTATTCAGTAGTCAAAATTTGAATCCGTAAGTATA TCTACTTTGCTTTGTTAAAACATCATGAGAGTGGAGGCCTGCCACCCAGAAAGGCACATACTAGTGCCTTTTAGTACAATTTTATGTCATGTAGAAGAAA ATGGCAATGTTCCTCCTATTGATACAGATACAGGCATATGTCATCTTATTGCGTTTTGCTTTATTGCACTTTGCAAATAATGCATTTTTTACAAATGGAA GGTTTATGGCAACTCTGCGTTGAGCCAGTCTATTGGTGCCATGTTTCCAATAAAACTTCTCCTTTCATGTCTCGT

refseq_FBXL5.F1 (forward primer)
refseq_FBXL5.R1 (reverse primer)
Single exon skipping

Frame 0

AGACARGRAASAPRRGCLWRGGGRGC*GGG*GS GDGALS*RSGRLHRPTLADEAAGGALLRQAF*NQ FFQQQRFPCSSAVFVCYFQGVQNA*AD*K*IHY WFASTTQPDHL*CTF*Q*TLRDA*PL*KGTEEC *AYYC*LEALPIT*NNRITIISCIICKIYILDSY SKNEYEQLNYAKQLKERLEAFTRDFLPHMKEEE EVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDT AELLRGLSLWNHAEERQKFFKYSVDEKSDKEAEV SEHSTGITHLPPEVMLSIFSYLNPQELCRCSQV SMKWSQLTKTGSLWKHLYPVHWARGDWYSGPAT ELDTEPDDEWVKNRKDESRAFHEWDEDADIDESE ESAEESIAISIAQMEKRLLHGLIHNVLPYVGTS VKTLVLAYSSAVSSKMVRQILELCPNLEHLDLT QTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITD VALEKISRALGILTSHQSGFLKTSTSKITSTAW KNKDITMQSTKQYACLHDLTNKGIGEEIDNEHP WTKPVSSENFTSPYVWMLDAEDLADIEDTVEWRH RNVESLCVMETASNFSCSTSGCFSKDIVGLRTS VCWQQHCASPAFAYCGHSFCCTGTALRTMSSLP ESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGR VLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHL NLSGCLTITGAGLQDLVSACPSLNDEYFYYCDN INGPHADTASGCQNLQCGFRACCRSGE*PLTSDL CLLHLAEQAFFHALYS*HISCVNHPFLSVTCFG PISYNFRNLNLPVNCNVVSLANYTFGLERD*VF SKG*EQSYIFLLNEML*RMLVMPCHLKYFIDNFE F*SPWR*LVLFTH*HCTKLCRSFPTHMSEDLFS KTAHFWKLISFP*YFLYFNDSQKANSNKPTFKV L*DYRINWLLSVSSVS*ESTNRYLFPLGILCSHH CPYVIKFGRDFLKYHNHLKKCINKIYFEDFTK* YCCVVIFIINLNPGLL*YRIGLHTLSLDLP*TY YPDK*F*TDTEFY*AEFSF*NELFSSQNLNP*VY LLCFVKTS*EWRPATQKGTY*CLLVQFYVM*KK MAMFLLLIQIQAYVILLRFALLHFANNAFFTNG RFMATLR*ASLLVPCFQ*NFSFHVS

Frame 1

RAHAQGGAPPLPRGEGVYGEAAAAAAEAEAEAV AMAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKT NFSNNNDFRALLQSLYATFKEFKMHEQIENEYII GLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNV KPTTVDWKPYQ*HKTIE*QLFHVLYVKYIYWIL TVRMNMNS*IMQNN*KRDWRLLQEIFFLT*KRKR RFFSPC*WNILPMKSLRILKRK*LHNTALRRIL QNSLEVLAYGIMLKSDRSFLNIPWMKSQIKKQK CQNTPQV*PIFLLR*CCQFSAILILKSYVDAVK* A*NGLS*QKRDRFGNIFTLFIGPEVTGIVVPQL NLILNLMMNG*KIGKMKVVLFMSGMKMLTLMNL KSLRRNQLLSALHKWKNVYSMA*FITFYHMLVLL *KP*Y*HTALQFPAKWLGRF*SFVLTWSIWILP RLTFQILHLTVGLGLVAARVFGILICLVVRKSQ MWP*RRFPELLEF*HLIKVAF*KHLQAKLLQLRG KIKTLPCSPPSSMPVCTI*LTRALEKK*IMNTP GLSLFLLRISLLLMCGC*MLKIWLILKILWNGD IEMLKVFV*WKQHPTLVVPPLVVLVRTLLD*GLV SVGSSIVLLQPLRIVVTHFVVQEQL*ELCHHSQ NLLQCVEKQQGLDCLGEKT*FTLGVKNLIKRLD VYFCFSVYLDVIRSQTMVSGF*LWEEGCLIWSTL ISLVVLL*LVQACRIWFQHVLL*MMNTFTTVTT LTVLMLIPPVDARICSVVFEPAAALANDP*LLI FVYFI*LSRLSFMHFTHSTFLVLTIPF*A*LVLA PFLTTSEILIYQ*IVMLFLLQIILLV*KGIRSF QKGENSLTFFF*MKCFKECW*CHVI*SIS*IIL SFKVHGGDWFSLHINTVPSFADLFRHTCLKTYFQ RQHIFGN*SLFRNISFISMILRRPIQTNPHLRF FRIIE*IGF*VLAQ*ARKAPIDICFL*GYFVLT TVPMSSNLGEIF*NTTII*RNV*IKSTLRTLPSN TVVL*FLL*ISIQVYFSIE*DYILCLWTSHELI TLTNSFRQILNFIELNFLFEMSYSVVKI*IRKY IYFALLKHHESGGLPPRKAHTSAF*YNFMSCRRK WQCSSY*YRYRHMSSYCVLLYCTLQIMHFLQME GLWQLCVEPVYWCHVSNKTSPFMSR

Frame 2

GRMRKGARRLCPAARVSMERRRPRLLRRRLRQW RWRPFLKKWTSSPPHTGG*SSWWGSTATSFLKP IFPTTTISVLFCSLCMLLSRSSKCMSRLKMNTL LVCFNNAARPFIMYILTINSPRCLASLKRD*RML SLLLLTGSLTNNIKQSNNNYFMYYM*NIYTGFL Q*E*I*TVKLCKTTEREIGGFYKRFSSSHERGR GGFSAHVNGIFYL*RA*GY*KESDCTTLLSEGYC RTP*RS*PMESC*RATEVF*IFRG*KVR*RSRS VRTLHRYNPSSS*GNAVNFQLS*SSRVMSMQSS KHEMVSADKNGIALETSLPCSLGQR*LV*WSRN* T*Y*T***MGEK*ER*KSCFS*VG*RC*H**I* RVCGGINCYQHCTNGKTFTPWLNS*RSTICWYF CKNLSISIQLCSFQQNG*ADFRALS*PGASGSYP D*HFRFCI*QLVLAWLLPESSAS*SVWL*ENHR CGPREDFQSSWNSDISSKWLFENIYKQNYFNCV EK*RHYHAVHQAVCLFARFN*QGHWRRNR**TPL D*ACFF*EFHFSLCVDVRC*RFG*Y*RYCGMET *KC*KSLCNGNSIQL*LFHLWLF**GHCWTKD* CLLAAALCFSSLCVLWSLILLYRNSFKNYVITPR IFCNV*KSSKD*IA*GKRLNLLWE*KI*SRDWT CTSVSQFIWMLSDHRPWSQGFDSGRRAALFGAP *SLWLSYYNWCRPAGFGFSMSFSE**ILLLL*QH *RSSC*YRQWMPEFAVWFSSLLPLWRMTLDF*S LSTSFS*AGFLSCTLLIAHFLC*PSLFERDLFW PHFLQLQKS*FTSEL*CCFSCKLYFWFRKGLGLF KRVRTVLHFSFK*NALKNVGNAMSFKVFHR*F* VLKSMEVIGSLYTLTLYQALQIFSDTHV*RLIF KDSTFLETNLFSVIFPLFQ*FSEGQFKQTHI*GS LGL*NKLASEC*LSELGKHQSIFVSFRDTLFSP LSLCHQIWERFFKIPQSFEEMYK*NLL*GLYQV ILLCCDFYYKSQSRFTLV*NRTTYFVFGPPMNLL P*QIVLDRY*ILLS*IFFLK*VIQ*SKFESVSI STLLC*NIMRVEACHPERHILVPFSTILCHVEE NGNVPPIDTDTGICHLIAFCFIALCK*CIFYKWK VYGNSALSQSIGAMFPIKLLLSCL