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Sequences

Sequence NM_001005366

CCAACAACAAAACAGCGATGCCACGGCGCTAACGGCGCCCGGTGCCTCCCGGGCTCCCTCCCCGCCCCATACCTCCTCGGGCCGCCGCCCCCACCCCCCC
AAGCCCGGGCCGAGAGCCCCCCCAAATAGCCCGGCCGCGGGCTCCGAGCGCGATCGGCAACAATGTTTACGTTCCGGGGATTATGACGTCGACGCCTCCC
CCCCCCCACAACTGCTGAAAATGGTTTCCTAGGACTTTGCAAACGGATCTGCCTAAGTGTTGGTGCAAAACTTTGTAGATCTCGGCTCTGGCTTGCTTTA
TTTATTTATTTTTTGGTTTGTTTTCTTTGGTCTTCCCTCCTTCCCCCCTCGGCCAAAATGCAGGGGGCAGGAGTGTTGACAATTAATTGGTGAACTCTCC
TAAAAAAATGGAGGCAGAGAAAGACTCTGGAAGAAGATTGCGCCCGATTGACCGCCAGCGATACGACGAGAACGAGGACTTGTCGGACGTGGAGGAGATC
GTCAGCGTCCGCGGCTTCAGCCTGGAGGAGAAGCTTCGCAGCCAGCTGTACCAGGGGGACTTCGTGCACGCCATGGAGGGCAAAGATTTCAACTATGAGT
ACGTACAGAGAGAAGCTCTCAGGGTTCCCCTGATATTTCGAGAAAAGGATGGACTGGGAATTAAGATGCCTGACCCTGATTTCACAGTCCGAGACGTCAA
ACTCCTAGTGGGGAGCCGGCGGCTTGTGGACGTGATGGATGTGAACACCCAGAAGGGCACGGAGATGAGCATGTCCCAGTTTGTGCGTTACTACGAGACG
CCCGAGGCCCAGCGGGACAAGCTGTACAACGTCATCAGCCTAGAGTTCAGCCACACCAAGCTGGAGCACTTGGTCAAGCGTCCGACTGTGGTAGACCTGG
TGGACTGGGTGGACAACATGTGGCCCCAGCATCTGAAGGAGAAGCAGACAGAAGCCACGAACGCCATTGCAGAGATGAAGTACCCGAAAGTGAAAAAGTA
CTGTCTGATGAGCGTGAAAGGTTGTTTCACCGACTTCCACATCGACTTTGGAGGCACTTCCGTTTGGTACCATGTTTTCCGGGGTGGGAAGATTTTTTGG
CTGATTCCTCCAACGCTGCACAATTTGGCGCTGTACGAGGAGTGGGTGCTGTCAGGCAAACAGAGTGACATCTTTCTGGGAGACCGTGTGGAACGATGCC
AAAGAATTGAGCTGAAGCAGGGCTACACATTTTTCATCCCTTCCGGTTGGATCCATGCCGTCTACACCCCTGTAGACTCTTTGGTGTTCGGCGGAAACAT
CCTGCACAGCTTTAACGTGCCCATGCAGCTGCGGATCTACGAGATCGAGGACAGGACGCGGGTGCAGCCCAAATTCCGTTACCCCTTCTACTATGAGATG
TGCTGGTATGTCCTGGAGAGATACGTGTACTGTGTGACCCAGCGCTCCCACCTCACTCAGGAATACCAGAGGGAGTCGATGCTTATTGATGCCCCGAGGA
AGCCCAGCATAGACGGCTTCTCTTCGGATTCCTGGCTGGAGATGGAGGAGGAGGCCTGTGATCAGCAGCCTCAGGAGGAGGAGGAGAAGGACGAGGAGGG
CGAGGGCAGGGACAGGGCACCCAAACCGCCCACCGATGGCTCCACTTCACCCACCAGCACGCCCTCTGAGGACCAGGAGGCCCTCGGGAAGAAGCCCAAA
GCACCTGCCCTGCGATTCCTCAAAAGGACTTTGTCTAATGAGTCGGAGGAAAGTGTGAAGTCCACCACATTGGCCGTAGACTACCCCAAGACCCCCACCG
GCTCTCCCGCCACGGAGGTCTCTGCCAAATGGACCCATCTCACTGAGTTTGAACTGAAGGGCCTGAAAGCTCTGGTGGAGAAACTGGAATCCCTCCCGGA
GAACAAGAAGTGTGTCCCCGAGGGCATCGAGGACCCCCAGGCACTCCTGGAGGGTGTGAAGAACGTCCTGAAGGAGCACGCAGATGATGACCCTAGTCTG
GCCATCACTGGGGTCCCTGTGGTGACTTGGCCAAAGAAGACTCCAAAGAACCGGGCTGTGGGTCGGCCCAAGGGGAAGCTGGGCCCGGCCTCCGCGGTGA
AGTTGGCCGCCAACCGGACAACGGCAGGAGCTCGGCGGCGCCGGACGCGATGCCGCAAGTGCGAGGCCTGCCTGCGGACCGAGTGCGGAGAGTGCCACTT
CTGCAAGGACATGAAGAAGTTCGGGGGCCCCGGGCGCATGAAGCAGAGCTGCATCATGCGGCAGTGCATCGCGCCAGTGCTGCCCCACACCGCCGTGTGC
CTTGTGTGTGGCGAGGCGGGGAAGGAAGACACGGTGGAAGAGGAGGAAGGCAAGTTTAACCTCATGCTCATGGAGTGCTCCATCTGCAATGAAATCATCC
ACCCTGGATGCCTTAAGATTAAGGAGTCAGAGGGTGTGGTCAACGACGAGCTTCCAAACTGCTGGGAGTGTCCGAAGTGTAACCACGCCGGCAAGACCGG
GAAACAAAAGCGTGGCCCTGGCTTTAAGTACGCCTCCAACCTGCCCGGCTCCCTGCTCAAGGAGCAGAAGATGAACCGGGACAACAAGGAAGGGCAGGAA
CCTGCCAAGCGGAGGAGTGAGTGTGAGGAGGCGCCCCGGCGCAGGTCGGATGAGCACTCGAAGAAGGTGCCGCCGGACGGCCTTCTGCGCAGAAAGTCTG
ACGACGTGC
ACCTGAGGAAGAAGCGGAAATACGAGAAGCCCCAGGAGCTGAGTGGACGCAAGCGGCTCAAACCTGGCAAAGAAGATAAGCTTTTCAGGAA
AAAGCGGCGGTCCTGGAAGAACGCCGAGGACCGCATGGCGCTGGCCAACAAGCCCCTCCGGCGCTTCAAGCAGGAACCCGAGGACGAACTGCCCGAGGCG
CCCCCCAAGACCAGGGAGAGCGACCACTCCCGCTCCAGCTCCCCCACCGCGGGACCCAGCACCGAAGGGGCCGAGGGCCCGGAGGAGAAGAAGAAGGTGA
AGATGCGCCGGAAGCGGCGGCTTCCCAACAAGGAGCTGAGCAGGGAGCTGAGCAAGGAGCTCAACCACGAGATCCAGAGGACGGAGAACAGCCTGGCCAA
CGAGAACCAGCAGCCCATCAAGTCGGAGCCTGAGAGCGAGGGCGAGGAGCCCAAGCGGCCCCCGGGCATCTGCGAGCGTCCCCACCGCTTCAGCAAGGGG
CTCAACGGCACCCCCCGGGAGCTGCGGCACCAGCTGGGGCCCAGCCTGCGCAGCCCGCCCCGTGTCATCTCCCGGCCCCCACCCTCCGTGTCCCCGCCCA
AGTGTATCCAGATGGAGCGCCATGTGATCCGGCCACCCCCCATCAGCCCCCCGCCTGACTCGCTACCCCTGGACGATGGGGCAGCCCACGTCATGCACAG
GGAGGTGTGGATGGCCGTCTTCAGCTACCTCAGCCACCAAGACCTGTGTGTGTGCATGCGGGTCTGCAGGACCTGGAACCGCTGGTGCTGCGATAAGCGG
TTGTGGACCCGCATTGACCTGAACCACTGCAAGTCTATCACACCCCTGATGCTGAGTGGCATCATCCGGCGACAGCCCGTCTCCCTCGACCTCAGCTGGA
CCAATATCTCCAAGAAGCAGCTGAGCTGGCTCATCAACCGGCTGCCTGGGCTCCGGGACTTGGTGCTGTCAGGCTGCTCATGGATCGCGGTCTCGGCCCT
TTGCAGCTCCAGTTGTCCGCTGCTCCGGACCCTGGATGTCCAGTGGGTGGAGGGACTAAAGGATGCCCAGATGCGGGATCTCCTGTCCCCGCCCACAGAC
AACAGGCCAGGTCAGATGGACAATCGGAGCAAGCTCCGGAACATCGTGGAGCTGCGCCTGGCAGGCCTGGACATCACAGATGCCTCCCTGCGGCTCATCA
TCCGCCACATGCCCCTGCTCTCCAAGCTCCACCTCAGTTACTGTAACCACGTCACCGACCAGTCTATCAACCTGCTCACTGCTGTTGGCACCACCACCCG
AGACTCCTTAACCGAGATCAACCTGTCTGACTGCAATAAGGTCACTGATCAGTGCCTGTCCTTCTTCAAACGCTGTGGAAACATCTGTCATATTGACCTG
AGGTACTGCAAGCAAGTCACCAAGGAAGGCTGTGAGCAGTTCATAGCCGAGATGTCTTCTTTCCAAGGGAGAAGCTGTTCAACCACCCGTTTGGGGGATG
AGTGAGCCGACACTTTCCTTTGGTCTTTCTGAATCGTAACTGCACTGCTTTCTGGACCATTTCTAAGGCGGCCTTTACAAGAAGACATTCCTGTCGGAGA
GGAGGGTGGACTTCGGAGAAATTCTCATACTGAAGCATGAGCTTAGGAGTTTCTGTTAGTGGTAGTGGTGTTTTGGACACTTCATTCCTTGCAACACCGA
GGTTTTGGGTGTTGACATAAAGTGGACCACACACCACATCTGCTGCCGTCTTGACACTTTTTTTTGTTTGGTTGGTTTTGTTACATCTTACATTATGCAG
AACTATTTTTGTACAAATTGTTTAAAAGTTATTTATGCAAGGTTTGAATGCATACCAGTGTTTTTATTGTTTTGAGATTGCCAATTTTCCTGATTTCCTT
AAGGTAGGAGAGAATTTAACGTGTACTTCATCGACACAACCCATCTACAAATGTGCCCAGATCTAACAAAGTAGGCTAAGACCTTCCACTTAAAAGCATG
TTTAACTGGAAGTTGAGAGTCTGCTTTGTACCTCAAGAGTTACATGAGCATGTTGTGGATAAATGTAAATTATAGTCAAAGTAAGATACTCTGCCAAGTT
TCCTCTGTAGAGAATTCACTTTTCTCAAATTTTAAAATTTCGACTTCAGCCTTTGCACTCAGGAGGTTCTGCTCCAGCATGAGCTCTTGTACTTACATAG
ATCTAATTTATACAGTGAGTCAAGACGTAGAATAAATGCTCCCACATAGCCTTTCTTTTGCTTTTGCTTCTCTCCTCTGAAGTGTGAGTTGAGTTCTCAT
TTAGGTTTGTAACATGGCTATTTCCTAGTTGTAAAGTTCTGCATTTATAAGTGCCATTGTTGTAAGGTGGTGTTTCCTAGACCTTCCCTGATGCGATTTT
ACCTTTGTTGAATTTGTATAAACAATTGTACAAAAAAAACCACTCTTGAACTTTGAGGGTTTCTGTTCTAGGAGTGGACTAGAAGTTTAAGCCCAGAGTC
AGTAAACACTGTTTTGAAGTCCAAA
  • refseq_FBXL10.F1 (forward primer)
  • refseq_FBXL10.R1 (reverse primer)
  • Single exon skipping

Frame 0

PTTKQRCHGANGARCLPGSLPAPYLLGPPPPPP
QARAESPPK*PGRGLRARSATMFTFRGL*RRRLP
PPTTAENGFLGLCKRICLSVGAKLCRSRLWLAL
FIYFLVCFLWSSLLPPSAKMQGAGVLTINW*TL
LKKWRQRKTLEEDCARLTASDTTRTRTCRTWRRS
SASAASAWRRSFAASCTRGTSCTPWRAKISTMS
TYREKLSGFP*YFEKRMDWELRCLTLISQSETS
NS*WGAGGLWT*WM*TPRRARR*ACPSLCVTTRR
PRPSGTSCTTSSA*SSATPSWSTWSSVRLW*TW
WTGWTTCGPSI*RRSRQKPRTPLQR*STRK*KS
TV**A*KVVSPTSTSTLEALPFGTMFSGVGRFFG
*FLQRCTIWRCTRSGCCQANRVTSFWETVWNDA
KELS*SRATHFSSLPVGSMPSTPL*TLWCSAET
SCTALTCPCSCGSTRSRTGRGCSPNSVTPSTMRC
AGMSWRDTCTV*PSAPTSLRNTRGSRCLLMPRG
SPA*TASLRIPGWRWRRRPVISSLRRRRRRTRR
ARAGTGHPNRPPMAPLHPPARPLRTRRPSGRSPK
HLPCDSSKGLCLMSRRKV*SPPHWP*TTPRPPP
ALPPRRSLPNGPISLSLN*RA*KLWWRNWNPSR
RTRSVSPRASRTPRHSWRV*RTS*RSTQMMTLVW
PSLGSLW*LGQRRLQRTGLWVGPRGSWARPPR*
SWPPTGQRQELGGAGRDAASARPACGPSAESAT
SART*RSSGAPGA*SRAASCGSASRQCCPTPPCA
LCVARRGRKTRWKRRKASLTSCSWSAPSAMKSS
TLDALRLRSQRVWSTTSFQTAGSVRSVTTPARP
GNKSVALALSTPPTCPAPCSRSRR*TGTTRKGRN
LPSGGVSVRRRPGAGRMSTRRRCRRTAFCAESL
TTC
T*GRSGNTRSPRS*VDASGSNLAKKISFSG
KSGGPGRTPRTAWRWPTSPSGASSRNPRTNCPRR
PPRPGRATTPAPAPPPRDPAPKGPRARRRRRR*
RCAGSGGFPTRS*AGS*ARSSTTRSRGRRTAWP
TRTSSPSSRSLRARARSPSGPRASASVPTASARG
STAPPGSCGTSWGPACAARPVSSPGPHPPCPRP
SVSRWSAM*SGHPPSAPRLTRYPWTMGQPTSCT
GRCGWPSSATSATKTCVCACGSAGPGTAGAAISG
CGPALT*TTASLSHP*C*VASSGDSPSPSTSAG
PISPRSS*AGSSTGCLGSGTWCCQAAHGSRSRP
FAAPVVRCSGPWMSSGWRD*RMPRCGISCPRPQT
TGQVRWTIGASSGTSWSCAWQAWTSQMPPCGSS
SATCPCSPSSTSVTVTTSPTSLSTCSLLLAPPP
ETP*PRSTCLTAIRSLISACPSSNAVETSVILT*
GTASKSPRKAVSSS*PRCLLSKGEAVQPPVWGM
SEPTLSFGLSES*LHCFLDHF*GGLYKKTFLSE
RRVDFGEILILKHELRSFC*W*WCFGHFIPCNTE
VLGVDIKWTTHHICCRLDTFFCLVGFVTSYIMQ
NYFCTNCLKVIYARFECIPVFLLF*DCQFS*FP
*GRREFNVYFIDTTHLQMCPDLTK*AKTFHLKAC
LTGS*ESALYLKSYMSMLWINVNYSQSKILCQV
SSVENSLFSNFKISTSAFALRRFCSSMSSCTYI
DLIYTVSQDVE*MLPHSLSFAFASLL*SVS*VLI
*VCNMAIS*L*SSAFISAIVVRWCFLDLP*CDF
TFVEFV*TIVQKKPLLNFEGFCSRSGLEV*AQS
Q*TLF*SP

Frame 1

QQQNSDATALTAPGASRAPSPPHTSSGRRPHPP
KPGPRAPPNSPAAGSERDRQQCLRSGDYDVDAS
PPPQLLKMVS*DFANGSA*VLVQNFVDLGSGLLY
LFIFWFVFFGLPSFPPRPKCRGQEC*QLIGELS
*KNGGRERLWKKIAPD*PPAIRRERGLVGRGGD
RQRPRLQPGGEASQPAVPGGLRARHGGQRFQL*V
RTERSSQGSPDISRKGWTGN*DA*P*FHSPRRQ
TPSGEPAACGRDGCEHPEGHGDEHVPVCALLRD
ARGPAGQAVQRHQPRVQPHQAGALGQASDCGRPG
GLGGQHVAPASEGEADRSHERHCRDEVPESEKV
LSDERERLFHRLPHRLWRHFRLVPCFPGWEDFL
ADSSNAAQFGAVRGVGAVRQTE*HLSGRPCGTMP
KN*AEAGLHIFHPFRLDPCRLHPCRLFGVRRKH
PAQL*RAHAAADLRDRGQDAGAAQIPLPLLL*D
VLVCPGEIRVLCDPALPPHSGIPEGVDAY*CPEE
AQHRRLLFGFLAGDGGGGL*SAASGGGGEGRGG
RGQGQGTQTAHRWLHFTHQHAL*GPGGPREEAQ
STCPAIPQKDFV**VGGKCEVHHIGRRLPQDPHR
LSRHGGLCQMDPSH*V*TEGPESSGGETGIPPG
EQEVCPRGHRGPPGTPGGCEERPEGARR**P*S
GHHWGPCGDLAKEDSKEPGCGSAQGEAGPGLRGE
VGRQPDNGRSSAAPDAMPQVRGLPADRVRRVPL
LQGHEEVRGPRAHEAELHHAAVHRASAAPHRRV
PCVWRGGEGRHGGRGGRQV*PHAHGVLHLQ*NHP
PWMP*D*GVRGCGQRRASKLLGVSEV*PRRQDR
ETKAWPWL*VRLQPARLPAQGAEDEPGQQGRAG
TCQAEE*V*GGAPAQVG*ALEEGAAGRPSAQKV*
RRA
PEEEAEIREAPGAEWTQAAQTWQRR*AFQE
KAAVLEERRGPHGAGQQAPPALQAGTRGRTARG
APQDQGERPLPLQLPHRGTQHRRGRGPGGEEEGE
DAPEAAASQQGAEQGAEQGAQPRDPEDGEQPGQ
REPAAHQVGA*ERGRGAQAAPGHLRASPPLQQG
AQRHPPGAAAPAGAQPAQPAPCHLPAPTLRVPAQ
VYPDGAPCDPATPHQPPA*LATPGRWGSPRHAQ
GGVDGRLQLPQPPRPVCVHAGLQDLEPLVLR*A
VVDPH*PEPLQVYHTPDAEWHHPATARLPRPQLD
QYLQEAAELAHQPAAWAPGLGAVRLLMDRGLGP
LQLQLSAAPDPGCPVGGGTKGCPDAGSPVPAHR
QQARSDGQSEQAPEHRGAAPGRPGHHRCLPAAHH
PPHAPALQAPPQLL*PRHRPVYQPAHCCWHHHP
RLLNRDQPV*LQ*GH*SVPVLLQTLWKHLSY*P
EVLQASHQGRL*AVHSRDVFFPREKLFNHPFGG*
VSRHFPLVFLNRNCTAFWTISKAAFTRRHSCRR
GGWTSEKFSY*SMSLGVSVSGSGVLDTSFLATP
RFWVLT*SGPHTTSAAVLTLFFVWLVLLHLTLCR
TIFVQIV*KLFMQGLNAYQCFYCFEIANFPDFL
KVGENLTCTSSTQPIYKCAQI*QSRLRPST*KH
V*LEVESLLCTSRVT*ACCG*M*IIVKVRYSAKF
PL*RIHFSQILKFRLQPLHSGGSAPA*ALVLT*
I*FIQ*VKT*NKCSHIAFLLLLLLSSEV*VEFS
FRFVTWLFPSCKVLHL*VPLL*GGVS*TFPDAIL
PLLNLYKQLYKKNHS*TLRVSVLGVD*KFKPRV
SKHCFEVQ

Frame 2

NNKTAMPRR*RRPVPPGLPPRPIPPRAAAPTPP
SPGREPPQIARPRAPSAIGNNVYVPGIMTSTPP
PPHNC*KWFPRTLQTDLPKCWCKTL*ISALACF
IYLFFGLFSLVFPPSPLGQNAGGRSVDN*LVNSP
KKMEAEKDSGRRLRPIDRQRYDENEDLSDVEEI
VSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYE
YVQREALRVPLIFREKDGLGIKMPDPDFTVRDVK
LLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYET
PEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDL
VDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKY
CLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFW
LIPPTLHNLALYEEWVLSGKQSDIFLGDRVERC
QRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNI
LHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEM
CWYVLERYVYCVTQRSHLTQEYQRESMLIDAPR
KPSIDGFSSDSWLEMEEEACDQQPQEEEEKDEEG
EGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPK
APALRFLKRTLSNESEESVKSTTLAVDYPKTPT
GSPATEVSAKWTHLTEFELKGLKALVEKLESLPE
NKKCVPEGIEDPQALLEGVKNVLKEHADDDPSL
AITGVPVVTWPKKTPKNRAVGRPKGKLGPASAV
KLAANRTTAGARRRRTRCRKCEACLRTECGECHF
CKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVC
LVCGEAGKEDTVEEEEGKFNLMLMECSICNEII
HPGCLKIKESEGVVNDELPNCWECPKCNHAGKTG
KQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQE
PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKS
DDV
HLRKKRKYEKPQELSGRKRLKPGKEDKLFRK
KRRSWKNAEDRMALANKPLRRFKQEPEDELPEA
PPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKV
KMRRKRRLPNKELSRELSKELNHEIQRTENSLAN
ENQQPIKSEPESEGEEPKRPPGICERPHRFSKG
LNGTPRELRHQLGPSLRSPPRVISRPPPSVSPP
KCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHR
EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKR
LWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSW
TNISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL
CSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTD
NRPGQMDNRSKLRNIVELRLAGLDITDASLRLI
IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTR
DSLTEINLSDCNKVTDQCLSFFKRCGNICHIDL
RYCKQVTKEGCEQFIAEMSSFQGRSCSTTRLGD
E*ADTFLWSF*IVTALLSGPFLRRPLQEDIPVGE
EGGLRRNSHTEA*A*EFLLVVVVFWTLHSLQHR
GFGC*HKVDHTPHLLPS*HFFLFGWFCYILHYA
ELFLYKLFKSYLCKV*MHTSVFIVLRLPIFLISL
R*ERI*RVLHRHNPSTNVPRSNKVG*DLPLKSM
FNWKLRVCFVPQELHEHVVDKCKL*SK*DTLPS
FLCREFTFLKF*NFDFSLCTQEVLLQHELLYLHR
SNLYSESRRRINAPT*PFFCFCFSPLKCELSSH
LGL*HGYFLVVKFCIYKCHCCKVVFPRPSLMRF
YLC*ICINNCTKKTTLEL*GFLF*EWTRSLSPES
VNTVLKSK

Sequence NM_032590

AAAAGTTAGGCAGTCCTTATAGGTATGGAAGCCGAGCTAATTTCCTTCTGAGCCCCCCAAATGCCTCCTCCACATGGCGGGTCCGCAAATGGGGGGATCT
GCAGAGGATCACCCCCCACGAAAAAGACATGCAGCAGAAAAGCAAAAAAAGAAAACAGTTATATATACAAAATGCTTTGAATTTGAGTCGGCCACACAGC
GCCCGATTGACCGCCAGCGATACGACGAGAACGAGGACTTGTCGGACGTGGAGGAGATCGTCAGCGTCCGCGGCTTCAGCCTGGAGGAGAAGCTTCGCAG
CCAGCTGTACCAGGGGGACTTCGTGCACGCCATGGAGGGCAAAGATTTCAACTATGAGTACGTACAGAGAGAAGCTCTCAGGGTTCCCCTGATATTTCGA
GAAAAGGATGGACTGGGAATTAAGATGCCTGACCCTGATTTCACAGTCCGAGACGTCAAACTCCTAGTGGGGAGCCGGCGGCTTGTGGACGTGATGGATG
TGAACACCCAGAAGGGCACGGAGATGAGCATGTCCCAGTTTGTGCGTTACTACGAGACGCCCGAGGCCCAGCGGGACAAGCTGTACAACGTCATCAGCCT
AGAGTTCAGCCACACCAAGCTGGAGCACTTGGTCAAGCGTCCGACTGTGGTAGACCTGGTGGACTGGGTGGACAACATGTGGCCCCAGCATCTGAAGGAG
AAGCAGACAGAAGCCACGAACGCCATTGCAGAGATGAAGTACCCGAAAGTGAAAAAGTACTGTCTGATGAGCGTGAAAGGTTGTTTCACCGACTTCCACA
TCGACTTTGGAGGCACTTCCGTTTGGTACCATGTTTTCCGGGGTGGGAAGATTTTTTGGCTGATTCCTCCAACGCTGCACAATTTGGCGCTGTACGAGGA
GTGGGTGCTGTCAGGCAAACAGAGTGACATCTTTCTGGGAGACCGTGTGGAACGATGCCAAAGAATTGAGCTGAAGCAGGGCTACACATTTTTCATCCCT
TCCGGTTGGATCCATGCCGTCTACACCCCTGTAGACTCTTTGGTGTTCGGCGGAAACATCCTGCACAGCTTTAACGTGCCCATGCAGCTGCGGATCTACG
AGATCGAGGACAGGACGCGGGTGCAGCCCAAATTCCGTTACCCCTTCTACTATGAGATGTGCTGGTATGTCCTGGAGAGATACGTGTACTGTGTGACCCA
GCGCTCCCACCTCACTCAGGAATACCAGAGGGAGTCGATGCTTATTGATGCCCCGAGGAAGCCCAGCATAGACGGCTTCTCTTCGGATTCCTGGCTGGAG
ATGGAGGAGGAGGCCTGTGATCAGCAGCCTCAGGAGGAGGAGGAGAAGGACGAGGAGGGCGAGGGCAGGGACAGGGCACCCAAACCGCCCACCGATGGCT
CCACTTCACCCACCAGCACGCCCTCTGAGGACCAGGAGGCCCTCGGGAAGAAGCCCAAAGCACCTGCCCTGCGATTCCTCAAAAGGACTTTGTCTAATGA
GTCGGAGGAAAGTGTGAAGTCCACCACATTGGCCGTAGACTACCCCAAGACCCCCACCGGCTCTCCCGCCACGGAGGTCTCTGCCAAATGGACCCATCTC
ACTGAGTTTGAACTGAAGGGCCTGAAAGCTCTGGTGGAGAAACTGGAATCCCTCCCGGAGAACAAGAAGTGTGTCCCCGAGGGCATCGAGGACCCCCAGG
CACTCCTGGAGGGTGTGAAGAACGTCCTGAAGGAGCACGCAGATGATGACCCTAGTCTGGCCATCACTGGGGTCCCTGTGGTGACTTGGCCAAAGAAGAC
TCCAAAGAACCGGGCTGTGGGTCGGCCCAAGGGGAAGCTGGGCCCGGCCTCCGCGGTGAAGTTGGCCGCCAACCGGACAACGGCAGGAGCTCGGCGGCGC
CGGACGCGATGCCGCAAGTGCGAGGCCTGCCTGCGGACCGAGTGCGGAGAGTGCCACTTCTGCAAGGACATGAAGAAGTTCGGGGGCCCCGGGCGCATGA
AGCAGAGCTGCATCATGCGGCAGTGCATCGCGCCAGTGCTGCCCCACACCGCCGTGTGCCTTGTGTGTGGCGAGGCGGGGAAGGAAGACACGGTGGAAGA
GGAGGAAGGCAAGTTTAACCTCATGCTCATGGAGTGCTCCATCTGCAATGAAATCATCCACCCTGGATGCCTTAAGATTAAGGAGTCAGAGGGTGTGGTC
AACGACGAGCTTCCAAACTGCTGGGAGTGTCCGAAGTGTAACCACGCCGGCAAGACCGGGAAACAAAAGCGTGGCCCTGGCTTTAAGTACGCCTCCAACC
TGCCCGGCTCCCTGCTCAAGGAGCAGAAGATGAACCGGGACAACAAGGAAGGGCAGGAACCTGCCAAGCGGAGGAGTGAGTGTGAGGAGGCGCCCCGGCG
CAGGTCGGATGAGCACTCGAAGAAGGTGCCGCCGGACGGCCTTCTGCGCAGAAAGTCTGACGACGTGCACCTGAGGAAGAAGCGGAAATACGAGAAGCCC
CAGGAGCTGAGTGGACGCAAGCGGGCCTCATCGCTTCAAACGTCCCCCGGTTCCTCCTCTCACCTCTCGCCGAGGCCCCCTCTAGGCAGCAGCCTCAGCC
CCTGGTGGAGATCCAGTCTCACTTACTTCCAGCAGCAG
CTCAAACCTGGCAAAGAAGATAAGCTTTTCAGGAAAAAGCGGCGGTCCTGGAAGAACGCCGA
GGACCGCATGGCGCTGGCCAACAAGCCCCTCCGGCGCTTCAAGCAGGAACCCGAGGACGAACTGCCCGAGGCGCCCCCCAAGACCAGGGAGAGCGACCAC
TCCCGCTCCAGCTCCCCCACCGCGGGACCCAGCACCGAAGGGGCCGAGGGCCCGGAGGAGAAGAAGAAGGTGAAGATGCGCCGGAAGCGGCGGCTTCCCA
ACAAGGAGCTGAGCAGGGAGCTGAGCAAGGAGCTCAACCACGAGATCCAGAGGACGGAGAACAGCCTGGCCAACGAGAACCAGCAGCCCATCAAGTCGGA
GCCTGAGAGCGAGGGCGAGGAGCCCAAGCGGCCCCCGGGCATCTGCGAGCGTCCCCACCGCTTCAGCAAGGGGCTCAACGGCACCCCCCGGGAGCTGCGG
CACCAGCTGGGGCCCAGCCTGCGCAGCCCGCCCCGTGTCATCTCCCGGCCCCCACCCTCCGTGTCCCCGCCCAAGTGTATCCAGATGGAGCGCCATGTGA
TCCGGCCACCCCCCATCAGCCCCCCGCCTGACTCGCTACCCCTGGACGATGGGGCAGCCCACGTCATGCACAGGGAGGTGTGGATGGCCGTCTTCAGCTA
CCTCAGCCACCAAGACCTGTGTGTGTGCATGCGGGTCTGCAGGACCTGGAACCGCTGGTGCTGCGATAAGCGGTTGTGGACCCGCATTGACCTGAACCAC
TGCAAGTCTATCACACCCCTGATGCTGAGTGGCATCATCCGGCGACAGCCCGTCTCCCTCGACCTCAGCTGGACCAATATCTCCAAGAAGCAGCTGAGCT
GGCTCATCAACCGGCTGCCTGGGCTCCGGGACTTGGTGCTGTCAGGCTGCTCATGGATCGCGGTCTCGGCCCTTTGCAGCTCCAGTTGTCCGCTGCTCCG
GACCCTGGATGTCCAGTGGGTGGAGGGACTAAAGGATGCCCAGATGCGGGATCTCCTGTCCCCGCCCACAGACAACAGGCCAGGTCAGATGGACAATCGG
AGCAAGCTCCGGAACATCGTGGAGCTGCGCCTGGCAGGCCTGGACATCACAGATGCCTCCCTGCGGCTCATCATCCGCCACATGCCCCTGCTCTCCAAGC
TCCACCTCAGTTACTGTAACCACGTCACCGACCAGTCTATCAACCTGCTCACTGCTGTTGGCACCACCACCCGAGACTCCTTAACCGAGATCAACCTGTC
TGACTGCAATAAGGTCACTGATCAGTGCCTGTCCTTCTTCAAACGCTGTGGAAACATCTGTCATATTGACCTGAGGTACTGCAAGCAAGTCACCAAGGAA
GGCTGTGAGCAGTTCATAGCCGAGATGTCTGTGAGTGTCCAGTTTGGGCAAGTAGAAGAAAAACTCCTGCAAAAACTGAGTTAGTCCAAGGATAAGTATG
TAAATACGGGGCGGGCTCTGGGAGGGGAGAGACTTTACAAAAATGAGGGCTTTTATTTTCCATTTGGAACGTGGGACAACAGACCACAACGCAATTCCAT
TTTGCAAGTCTTTCCAAGGGAGAAGCTGTTCAACCACCCGTTTGGGGGATGAGTGAGCCGACACTTTCCTTTGGTCTTTCTGAATCGTAACTGCACTGCT
TTCTGGACCATTTCTAAGGCGGCCTTTACAAGAAGACATTCCTGTCGGAGAGGAGGGTGGACTTCGGAGAAATTCTCATACTGAAGCATGAGCTTAGGAG
TTTCTGTTAGTGGTAGTGGTGTTTTGGACACTTCATTCCTTGCAACACCGAGGTTTTGGGTGTTGACATAAAGTGGACCACACACCACATCTGCTGCCGT
CTTGACACTTTTTTTTGTTTGGTTGGTTTTGTTACATCTTACATTATGCAGAACTATTTTTGTACAAATTGTTTAAAAGTTATTTATGCAAGGTTTGAAT
GCATACCAGTGTTTTTATTGTTTTGAGATTGCCAATTTTCCTGATTTCCTTAAGGTAGGAGAGAATTTAACGTGTACTTCATCGACACAACCCATCTACA
AATGTGCCCAGATCTAACAAAGTAGGCTAAGACCTTCCACTTAAAAGCATGTTTAACTGGAAGTTGAGAGTCTGCTTTGTACCTCAAGAGTTACATGAGC
ATGTTGTGGATAAATGTAAATTATAGTCAAAGTAAGATACTCTGCCAAGTTTCCTCTGTAGAGAATTCACTTTTCTCAAATTTTAAAATTTCGACTTCAG
CCTTTGCACTCAGGAGGTTCTGCTCCAGCATGAGCTCTTGTACTTACATAGATCTAATTTATACAGTGAGTCAAGACGTAGAATAAATGCTCCCACATAG
CCTTTCTTTTGCTTTTGCTTCTCTCCTCTGAAGTGTGAGTTGAGTTCTCATTTAGGTTTGTAACATGGCTATTTCCTAGTTGTAAAGTTCTGCATTTATA
AGTGCCATTGTTGTAAGGTGGTGTTTCCTAGACCTTCCCTGATGCGATTTTACCTTTGTTGAATTTGTATAAACAATTGTACAAAAAAAACCACTCTTGA
ACTTTGAGGGTTTCTGTTCTAGGAGTGGACTAGAAGTTTAAGCCCAGAGTCAGTAAACACTGTTTTGAAGTCCAAA
  • refseq_FBXL10.F1 (forward primer)
  • refseq_FBXL10.R1 (reverse primer)
  • Single exon skipping

Frame 0

KS*AVLIGMEAELISF*APQMPPPHGGSANGGI
CRGSPPTKKTCSRKAKKENSYIYKML*I*VGHTA
PD*PPAIRRERGLVGRGGDRQRPRLQPGGEASQ
PAVPGGLRARHGGQRFQL*VRTERSSQGSPDIS
RKGWTGN*DA*P*FHSPRRQTPSGEPAACGRDGC
EHPEGHGDEHVPVCALLRDARGPAGQAVQRHQP
RVQPHQAGALGQASDCGRPGGLGGQHVAPASEG
EADRSHERHCRDEVPESEKVLSDERERLFHRLPH
RLWRHFRLVPCFPGWEDFLADSSNAAQFGAVRG
VGAVRQTE*HLSGRPCGTMPKN*AEAGLHIFHP
FRLDPCRLHPCRLFGVRRKHPAQL*RAHAAADLR
DRGQDAGAAQIPLPLLL*DVLVCPGEIRVLCDP
ALPPHSGIPEGVDAY*CPEEAQHRRLLFGFLAG
DGGGGL*SAASGGGGEGRGGRGQGQGTQTAHRWL
HFTHQHAL*GPGGPREEAQSTCPAIPQKDFV**
VGGKCEVHHIGRRLPQDPHRLSRHGGLCQMDPS
H*V*TEGPESSGGETGIPPGEQEVCPRGHRGPPG
TPGGCEERPEGARR**P*SGHHWGPCGDLAKED
SKEPGCGSAQGEAGPGLRGEVGRQPDNGRSSAA
PDAMPQVRGLPADRVRRVPLLQGHEEVRGPRAHE
AELHHAAVHRASAAPHRRVPCVWRGGEGRHGGR
GGRQV*PHAHGVLHLQ*NHPPWMP*D*GVRGCG
QRRASKLLGVSEV*PRRQDRETKAWPWL*VRLQP
ARLPAQGAEDEPGQQGRAGTCQAEE*V*GGAPA
QVG*ALEEGAAGRPSAQKV*RRAPEEEAEIREA
PGAEWTQAGLIASNVPRFLLSPLAEAPSRQQPQP
LVEIQSHLLPAA
AQTWQRR*AFQEKAAVLEERR
GPHGAGQQAPPALQAGTRGRTARGAPQDQGERP
LPLQLPHRGTQHRRGRGPGGEEEGEDAPEAAASQ
QGAEQGAEQGAQPRDPEDGEQPGQREPAAHQVG
A*ERGRGAQAAPGHLRASPPLQQGAQRHPPGAA
APAGAQPAQPAPCHLPAPTLRVPAQVYPDGAPCD
PATPHQPPA*LATPGRWGSPRHAQGGVDGRLQL
PQPPRPVCVHAGLQDLEPLVLR*AVVDPH*PEP
LQVYHTPDAEWHHPATARLPRPQLDQYLQEAAEL
AHQPAAWAPGLGAVRLLMDRGLGPLQLQLSAAP
DPGCPVGGGTKGCPDAGSPVPAHRQQARSDGQS
EQAPEHRGAAPGRPGHHRCLPAAHHPPHAPALQA
PPQLL*PRHRPVYQPAHCCWHHHPRLLNRDQPV
*LQ*GH*SVPVLLQTLWKHLSY*PEVLQASHQG
RL*AVHSRDVCECPVWASRRKTPAKTELVQG*VC
KYGAGSGRGETLQK*GLLFSIWNVGQQTTTQFH
FASLSKGEAVQPPVWGMSEPTLSFGLSES*LHC
FLDHF*GGLYKKTFLSERRVDFGEILILKHELRS
FC*W*WCFGHFIPCNTEVLGVDIKWTTHHICCR
LDTFFCLVGFVTSYIMQNYFCTNCLKVIYARFE
CIPVFLLF*DCQFS*FP*GRREFNVYFIDTTHLQ
MCPDLTK*AKTFHLKACLTGS*ESALYLKSYMS
MLWINVNYSQSKILCQVSSVENSLFSNFKISTS
AFALRRFCSSMSSCTYIDLIYTVSQDVE*MLPHS
LSFAFASLL*SVS*VLI*VCNMAIS*L*SSAFI
SAIVVRWCFLDLP*CDFTFVEFV*TIVQKKPLL
NFEGFCSRSGLEV*AQSQ*TLF*SP

Frame 1

KVRQSL*VWKPS*FPSEPPKCLLHMAGPQMGGS
AEDHPPRKRHAAEKQKKKTVIYTKCFEFESATQ
RPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRS
QLYQGDFVHAMEGKDFNYEYVQREALRVPLIFR
EKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMD
VNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISL
EFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKE
KQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFH
IDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEE
WVLSGKQSDIFLGDRVERCQRIELKQGYTFFIP
SGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIY
EIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQ
RSHLTQEYQRESMLIDAPRKPSIDGFSSDSWLE
MEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDG
STSPTSTPSEDQEALGKKPKAPALRFLKRTLSNE
SEESVKSTTLAVDYPKTPTGSPATEVSAKWTHL
TEFELKGLKALVEKLESLPENKKCVPEGIEDPQ
ALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKT
PKNRAVGRPKGKLGPASAVKLAANRTTAGARRR
RTRCRKCEACLRTECGECHFCKDMKKFGGPGRM
KQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEE
EEGKFNLMLMECSICNEIIHPGCLKIKESEGVV
NDELPNCWECPKCNHAGKTGKQKRGPGFKYASN
LPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRR
RSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKP
QELSGRKRASSLQTSPGSSSHLSPRPPLGSSLS
PWWRSSLTYFQQQ
LKPGKEDKLFRKKRRSWKNAE
DRMALANKPLRRFKQEPEDELPEAPPKTRESDH
SRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLP
NKELSRELSKELNHEIQRTENSLANENQQPIKSE
PESEGEEPKRPPGICERPHRFSKGLNGTPRELR
HQLGPSLRSPPRVISRPPPSVSPPKCIQMERHV
IRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSY
LSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNH
CKSITPLMLSGIIRRQPVSLDLSWTNISKKQLS
WLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLR
TLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNR
SKLRNIVELRLAGLDITDASLRLIIRHMPLLSK
LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLS
DCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKE
GCEQFIAEMSVSVQFGQVEEKLLQKLS*SKDKY
VNTGRALGGERLYKNEGFYFPFGTWDNRPQRNSI
LQVFPREKLFNHPFGG*VSRHFPLVFLNRNCTA
FWTISKAAFTRRHSCRRGGWTSEKFSY*SMSLG
VSVSGSGVLDTSFLATPRFWVLT*SGPHTTSAAV
LTLFFVWLVLLHLTLCRTIFVQIV*KLFMQGLN
AYQCFYCFEIANFPDFLKVGENLTCTSSTQPIY
KCAQI*QSRLRPST*KHV*LEVESLLCTSRVT*A
CCG*M*IIVKVRYSAKFPL*RIHFSQILKFRLQ
PLHSGGSAPA*ALVLT*I*FIQ*VKT*NKCSHI
AFLLLLLLSSEV*VEFSFRFVTWLFPSCKVLHL*
VPLL*GGVS*TFPDAILPLLNLYKQLYKKNHS*
TLRVSVLGVD*KFKPRVSKHCFEVQ

Frame 2

KLGSPYRYGSRANFLLSPPNASSTWRVRKWGDL
QRITPHEKDMQQKSKKRKQLYIQNALNLSRPHS
ARLTASDTTRTRTCRTWRRSSASAASAWRRSFA
ASCTRGTSCTPWRAKISTMSTYREKLSGFP*YFE
KRMDWELRCLTLISQSETSNS*WGAGGLWT*WM
*TPRRARR*ACPSLCVTTRRPRPSGTSCTTSSA
*SSATPSWSTWSSVRLW*TWWTGWTTCGPSI*RR
SRQKPRTPLQR*STRK*KSTV**A*KVVSPTST
STLEALPFGTMFSGVGRFFG*FLQRCTIWRCTR
SGCCQANRVTSFWETVWNDAKELS*SRATHFSSL
PVGSMPSTPL*TLWCSAETSCTALTCPCSCGST
RSRTGRGCSPNSVTPSTMRCAGMSWRDTCTV*P
SAPTSLRNTRGSRCLLMPRGSPA*TASLRIPGWR
WRRRPVISSLRRRRRRTRRARAGTGHPNRPPMA
PLHPPARPLRTRRPSGRSPKHLPCDSSKGLCLM
SRRKV*SPPHWP*TTPRPPPALPPRRSLPNGPIS
LSLN*RA*KLWWRNWNPSRRTRSVSPRASRTPR
HSWRV*RTS*RSTQMMTLVWPSLGSLW*LGQRR
LQRTGLWVGPRGSWARPPR*SWPPTGQRQELGGA
GRDAASARPACGPSAESATSART*RSSGAPGA*
SRAASCGSASRQCCPTPPCALCVARRGRKTRWK
RRKASLTSCSWSAPSAMKSSTLDALRLRSQRVWS
TTSFQTAGSVRSVTTPARPGNKSVALALSTPPT
CPAPCSRSRR*TGTTRKGRNLPSGGVSVRRRPG
AGRMSTRRRCRRTAFCAESLTTCT*GRSGNTRSP
RS*VDASGPHRFKRPPVPPLTSRRGPL*AAASA
PGGDPVSLTSSSS
SNLAKKISFSGKSGGPGRTP
RTAWRWPTSPSGASSRNPRTNCPRRPPRPGRATT
PAPAPPPRDPAPKGPRARRRRRR*RCAGSGGFP
TRS*AGS*ARSSTTRSRGRRTAWPTRTSSPSSR
SLRARARSPSGPRASASVPTASARGSTAPPGSCG
TSWGPACAARPVSSPGPHPPCPRPSVSRWSAM*
SGHPPSAPRLTRYPWTMGQPTSCTGRCGWPSSA
TSATKTCVCACGSAGPGTAGAAISGCGPALT*TT
ASLSHP*C*VASSGDSPSPSTSAGPISPRSS*A
GSSTGCLGSGTWCCQAAHGSRSRPFAAPVVRCS
GPWMSSGWRD*RMPRCGISCPRPQTTGQVRWTIG
ASSGTSWSCAWQAWTSQMPPCGSSSATCPCSPS
STSVTVTTSPTSLSTCSLLLAPPPETP*PRSTC
LTAIRSLISACPSSNAVETSVILT*GTASKSPRK
AVSSS*PRCL*VSSLGK*KKNSCKN*VSPRISM
*IRGGLWEGRDFTKMRAFIFHLERGTTDHNAIP
FCKSFQGRSCSTTRLGDE*ADTFLWSF*IVTALL
SGPFLRRPLQEDIPVGEEGGLRRNSHTEA*A*E
FLLVVVVFWTLHSLQHRGFGC*HKVDHTPHLLP
S*HFFLFGWFCYILHYAELFLYKLFKSYLCKV*M
HTSVFIVLRLPIFLISLR*ERI*RVLHRHNPST
NVPRSNKVG*DLPLKSMFNWKLRVCFVPQELHE
HVVDKCKL*SK*DTLPSFLCREFTFLKF*NFDFS
LCTQEVLLQHELLYLHRSNLYSESRRRINAPT*
PFFCFCFSPLKCELSSHLGL*HGYFLVVKFCIY
KCHCCKVVFPRPSLMRFYLC*ICINNCTKKTTLE
L*GFLF*EWTRSLSPESVNTVLKSK

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